Advances in Carbohydrate Chemistry and Biochemistry

Obituaries 1. Stephen John Charles Angyal

The Andrews Lectures

Administration

Acknowledgments

List of Publications by S. J. Angyal

Obituaries 2. John Grant Buchanan

List of Publications by J. Grant Buchanan

Obituaries 3. Saul Roseman

Biosynthesis and Metabolism of Simple Sugars

Biosynthesis of Mucin Glycoproteins and Brain Gangliosides

Discovery of the Sialyltransferase Catalyzing the In Vitro Biosynthesis of Sialyl-Lactose

Biosynthesis of Oligoglycosyl-Glycoproteins Studied at the Johns Hopkins University (1965–1970)

Bacterial Phosphotransferase System (PTS) Studied at the Johns Hopkins University (1965–1985)

Intercellular Adhesion and the “Fish Theory” from the Johns Hopkins University (1966–1972)

Degradation of Chitin and Hexosamine Metabolism in the Sea World (1985–2011)

Acknowledgments

References

Chapter 4. De novo asymmetric synthesis of the pyranoses: From monosaccharides to oligosaccharides

Abstract

Abbreviations

I Introduction

II Masamune–Sharpless Approach to the Hexoses

III Danishefsky Hetereo-Diels–Alder Approach to Various Pyranoses

IV MacMillan Iterative Aldol Approach to Various Pyranoses

V Asymmetric Oxidative Biocatalytic Aldol Approach to Various Pyranoses

VI Sharpless Dihydroxylation/Enzymatic Aldol Approach 2-Ketoses

VII Non-De Novo Asymmetric Approaches to Pyranoses

VIII O’Doherty De Novo Approach to Pyranoses

Acknowledgments

References

Chapter 5. Recent advances toward the development of inhibitors to attenuate tumor metastasis via the interruption of lectin–ligand interactions

Abstract

Abbreviations

I Introduction

II Roles of Carbohydrates in Tumor Development

III Roles of Lectins in Tumor Development

IV Developing Anticancer Approaches by Targeting Tumor-Associated Carbohydrate–Lectin Systems

V Conclusions

References

Chapter 6. Bacterial cell-envelope glycoconjugates

Abstract

Abbreviations

I Introduction

II Surface-Layer Glycoproteins

III Nonclassical Secondary Cell-Envelope Polysaccharides

IV Structural Analysis

V Cell-Envelope Glycan Biosynthesis

VI Glycan Engineering and Applications

VII Concluding Remarks

References

Author Index

Subject Index