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Elsevier

Advances in Genetics

  • 1 Edición, Volumen 87 - 9 de octubre de 2014
  • Última edición
  • Editores: Theodore Friedmann, Jay C. Dunlap, Stephen F. Goodwin
  • Idioma: Inglés

The field of genetics is rapidly evolving, and new medical breakthroughs are occurring as a result of advances in our knowledge of genetics. Advances in Genetics continual… Leer más

Descripción

The field of genetics is rapidly evolving, and new medical breakthroughs are occurring as a result of advances in our knowledge of genetics. Advances in Genetics continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines.

Volume 87 presents an eclectic mix of articles of use to all human and molecular geneticists on topics including: gene transfer, fruiting body development and the genetics of Alzheimer’s disease; and more.

Puntos claves

  • Includes methods for testing with ethical, legal, and social implications
  • Critically analyzes future directions
  • Written and edited by recognized leaders in the field

De interès para

Molecular geneticists, clinical geneticists, neurologists, neuroscientists, molecular biologists, and biochemists.

Índice

  • Advances in Genetics, Volume 87
  • Chapter One. Opportunity for Selection in Human Health
    • 1. Introduction
    • 2. Genetic Variation and Demographic Selection
    • 3. Episodes of Selection
    • 4. Selection Spectra
    • 5. Place of Multilevel Selection in Medical Practice and Public Health
    • 6. Discussion
  • Chapter Two. Clinical Applications Involving CNS Gene Transfer
    • 1. Introduction
    • 2. CNS Clinical Trials Utilizing Retroviral Vectors
    • 3. CNS Clinical Trials Utilizing AAV Vectors
    • 4. Lessons Learned from Related Studies
    • 5. Conclusion
  • Chapter Three. Methods for Gene Transfer to the Central Nervous System
    • 1. Introduction
    • 2. Vectors for CNS Gene Transfer
    • 3. Genome Designs for Optimal Expressions
    • 4. Conclusions
  • Chapter Four. The Filamentous Fungus Sordaria macrospora as a Genetic Model to Study Fruiting Body Development
    • 1. Introduction
    • 2. Genetic and Genomic Tools
    • 3. The Striatin-Interacting Phosphatase and Kinase Complex, a Multisubunit Protein Complex Governing Fruiting Body Development
    • 4. Chromatin-Related Processes
    • 5. Metabolism-Related Developmental Processes
    • 6. Autophagy
    • 7. Concluding Remarks and Outlook
  • Chapter Five. Genetics of Alzheimer’s Disease
    • 1. Introduction
    • 2. Heritability of Alzheimer’s Disease
    • 3. Genetic Causes of Early-Onset Alzheimer’s Disease
    • 4. Genetic Risk Factors for Late-Onset Alzheimer’s Disease
    • 5. Discussion
  • Index

Reseñas

Praise for previous volumes in the series: "Outstanding both in variety and in the quality of its contributions."–Nature

"Can be highly recommended to geneticists, and biologists in general...will prove to be of high importance for the development of the science of genetics."—Science

Detalles del producto

  • Edición: 1
  • Última edición
  • Volumen: 87
  • Publicado: 9 de octubre de 2014
  • Idioma: Inglés

Sobre los editores

TF

Theodore Friedmann

School of Medicine, University of California at San Diego, USA
Afiliaciones y experiencia
School of Medicine, University of California at San Diego, USA

JD

Jay C. Dunlap

Dr. Jay Dunlap works at the Geisel School of Medicine at Dartmouth.
Afiliaciones y experiencia
The Geisel School of Medicine, Dartmouth, NH, USA

SG

Stephen F. Goodwin

Dr. Stephen Goodwin works at the University of Oxford.
Afiliaciones y experiencia
University of Oxford, UK

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