Advances in Mitochondrial Drug Delivery
From Molecular Mechanisms to Clinical Translation
- 1 Edición - 1 de marzo de 2027
- Última edición
- Editor: Prashant Kesharwani
- Idioma: Inglés
Advances in Mitochondrial Drug Delivery: From Molecular Mechanisms to Clinical Translation addresses the critical need for a comprehensive resource on mitochondrial-targeted drug d… Leer más
Descripción
Descripción
Advances in Mitochondrial Drug Delivery: From Molecular Mechanisms to Clinical Translation addresses the critical need for a comprehensive resource on mitochondrial-targeted drug delivery systems. As recent advancements in drug delivery systems (DDS) have shown substantial promise in treating diseases linked to mitochondrial dysfunction, there is a pressing demand for a consolidated reference that covers both the foundational aspects and the latest innovations in this field. The book's Table of Contents encompasses a wide range of topics, beginning with the fundamentals of mitochondrial biology and drug delivery, followed by various mitochondrial-targeted drug delivery strategies. It further explores advanced applications of these systems in treating cancer, neurodegenerative diseases, cardiovascular conditions, and more. Additionally, the book discusses future directions, clinical translation, and regulatory challenges, ensuring a holistic view of the subject matter. Advances in Mitochondrial Drug Delivery offers significant benefits to researchers, students, and professionals in pharmaceutical sciences and nanotechnology. By integrating diverse perspectives from leading experts, the book serves as an essential resource for understanding the complexities of mitochondrial-targeted therapies, thereby fostering advancements in drug delivery systems and therapeutic strategies.
Puntos claves
Puntos claves
- Provides a comprehensive exploration of mitochondrial targeting strategies from fundamentals to advanced applications
- Analyses novel drug delivery systems utilizing mitochondria for therapeutic benefits
- Organizes content with illustrative figures and tables enhancing reader comprehension and engagement
- Addresses current challenges in clinical translation and regulatory aspects of mitochondrial drug delivery
De interès para
De interès para
Graduate and postgraduate students in pharmaceutical sciences
Índice
Índice
SECTION 1: Fundamentals of Mitochondrial Biology & Drug Delivery
1. Introduction to Mitochondrial Structure and Function
2. Mitochondrial Dysfunction and Its Role in Disease Pathophysiology
3. Role of Mitochondria in Cancer Metabolism
4. Cellular and Subcellular Targeting: Challenges in Mitochondrial Drug Delivery
5. Mechanisms of Mitochondrial Targeting
6. Mitochondrial Biogenesis and Metabolic Reprogramming
SECTION 2: Mitochondria-Targeted Drug Delivery Strategies
7. Concept of Mito-Porters, Mitochondriotropics, and Mitocans
8. Lipophilic Cation-Based Mitochondrial Targeting
9. Mitochondria-Penetrating Peptides (MPPs) and Peptide-Based Targeting
10. Nanoparticle-Based Mitochondrial Targeting
11. Mitochondria-Targeted Prodrugs and Small Molecule Therapeutics
12. Transporter-Mediated Mitochondrial Drug Delivery
13. Mitochondria-Targeted Gene Therapy and RNA Delivery
14. Stimuli-Responsive Mitochondria-Targeted Drug Delivery
15. Mitochondria-Targeted Photodynamic and Photothermal Therapy
SECTION 3: Applications of Mitochondria-Targeted Therapeutics
16. Mitochondria-Targeted Drug Delivery for Cancer Therapy
17. Mitochondria-Targeted Therapeutics for Neurodegenerative Diseases
18. Mitochondria in Cardiovascular and Metabolic Diseases
19. Mitochondria-Targeted Approaches for Infectious Diseases
20. Emerging Therapies for Mitochondrial Genetic Disorders
SECTION 4: Future Directions, Clinical Translation, and Regulatory Aspects
21. Ethical Considerations in Mitochondrial Gene Therapy
22. Advances in Mitochondria-Targeted Drug Discovery and Development
23. Clinical Translation, Regulatory Challenges, and Future Perspectives
1. Introduction to Mitochondrial Structure and Function
2. Mitochondrial Dysfunction and Its Role in Disease Pathophysiology
3. Role of Mitochondria in Cancer Metabolism
4. Cellular and Subcellular Targeting: Challenges in Mitochondrial Drug Delivery
5. Mechanisms of Mitochondrial Targeting
6. Mitochondrial Biogenesis and Metabolic Reprogramming
SECTION 2: Mitochondria-Targeted Drug Delivery Strategies
7. Concept of Mito-Porters, Mitochondriotropics, and Mitocans
8. Lipophilic Cation-Based Mitochondrial Targeting
9. Mitochondria-Penetrating Peptides (MPPs) and Peptide-Based Targeting
10. Nanoparticle-Based Mitochondrial Targeting
11. Mitochondria-Targeted Prodrugs and Small Molecule Therapeutics
12. Transporter-Mediated Mitochondrial Drug Delivery
13. Mitochondria-Targeted Gene Therapy and RNA Delivery
14. Stimuli-Responsive Mitochondria-Targeted Drug Delivery
15. Mitochondria-Targeted Photodynamic and Photothermal Therapy
SECTION 3: Applications of Mitochondria-Targeted Therapeutics
16. Mitochondria-Targeted Drug Delivery for Cancer Therapy
17. Mitochondria-Targeted Therapeutics for Neurodegenerative Diseases
18. Mitochondria in Cardiovascular and Metabolic Diseases
19. Mitochondria-Targeted Approaches for Infectious Diseases
20. Emerging Therapies for Mitochondrial Genetic Disorders
SECTION 4: Future Directions, Clinical Translation, and Regulatory Aspects
21. Ethical Considerations in Mitochondrial Gene Therapy
22. Advances in Mitochondria-Targeted Drug Discovery and Development
23. Clinical Translation, Regulatory Challenges, and Future Perspectives
Detalles del producto
Detalles del producto
- Edición: 1
- Última edición
- Publicado: 1 de marzo de 2027
- Idioma: Inglés
Sobre el editor
Sobre el editor
PK
Prashant Kesharwani
Dr. Prashant Kesharwani is an Assistant Professor of Pharmaceutics at Dr. Harisingh Gour Vishwavidyalaya (A Central University), Sagar, India. His work focuses on translational nanomedicine, polymeric biomaterials, targeted drug delivery, nanoengineered drug delivery systems, and translational pharmaceutical research. He has contributed extensively to the scientific literature and has served as an editor of scholarly books. Dr. Kesharwani has received research funding from national agencies and has been recognized with awards and fellowships for his contributions to the field. His research interests include nanomedicine, targeted and stimuli-responsive drug delivery, polymeric nanocarriers, and related pharmaceutical applications. He is actively involved in scientific research, academic mentoring, and scholarly publishing.
Afiliaciones y experiencia
Dr. Harisingh Gour Vishwavidyalaya University, India