Hereditary Syndromes Associated with Endocrine Tumors

Volume 134, Hereditary Syndromes Associated with Endocrine Tumors, provides a comprehensive and up-to-date overview of the genetic, molecular, clinical, diagnostic, and therapeutic aspects of inherited endocrine neoplasia syndromes. Over the past two decades, remarkable advances in genomics, molecular diagnostics, and precision medicine have transformed the understanding and management of hereditary endocrine tumor syndromes, enabling earlier diagnosis, individualized surveillance strategies, targeted therapies, and improved patient outcomes. This volume brings together contributions from internationally recognized experts to review the current state of knowledge on both well-established and emerging hereditary syndromes affecting the endocrine system. The chapters cover the genetic basis, genotype–phenotype correlations, clinical manifestations, screening recommendations, multidisciplinary management, and future therapeutic perspectives for syndromes predisposing to tumors of the adrenal glands, pituitary, thyroid, parathyroid, pancreas, and neuroendocrine tissues. Special emphasis is placed on recent discoveries in cancer predisposition genes, advances in molecular pathology, the integration of next-generation sequencing into clinical practice, and the implications of hereditary cancer syndromes for patients and their families.