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Elsevier

Indole Alkaloids

Spirooxindole

  • 1 Edición - 30 de enero de 2022
  • Última edición
  • Autores: Maliha Uroos, Abdul Hameed, Sadia Naz, Muhammad Raza Shah
  • Idioma: Inglés

Indole Alkaloids: Spirooxindole details the multistep synthesis of natural products using schematic diagrams, providing a quick-and-easy way to review and understand new and novel… Leer más

Descripción

Indole Alkaloids: Spirooxindole details the multistep synthesis of natural products using schematic diagrams, providing a quick-and-easy way to review and understand new and novel synthetic strategies to construct structural frameworks of natural products. As a volume in the Visual Guides to Natural Product Synthesis series, this book presents the schematic total syntheses of natural products containing a “spirooxindole” core structure. It covers spirooxindole molecules through visual diagrams, highlighting key steps involved in total, formal and semi-syntheses. Sections cover Brevianamide A and B, Citrinadin A and B, Coerulescine and Horsfiline, Elacomine and Isoelacomine, Gelsemine, Paraherquamide A and B, Rynchophylline, Isorynchophylline, and more.

Visual layouts provide quick-and- easy access to developed synthetic routes towards the targeted spirooxindoles.

Puntos claves

  • Outlines synthetic strategies for natural products bearing a spirooxindole core structure
  • Includes schematic diagrams of multistep synthetic routes, highlighting key steps along the way
  • Describes all routes for the formal synthesis, semi-synthesis and total synthesis of spirooxindole alkaloids

De interès para

Researchers working in the area of organic synthesis and natural products, especially those who are involved in the development of new, efficient and novel methodologies for natural product synthesis

Índice

1. Indole alkaloids; Spirooxindoles

2. Brevianamide A and B

3. Citrinadin A and B

4. Coerulescine and Horsfiline

5. (±)-Elacomine and (±)-Isoelacomine

6. Gelsemine

7. Paraherquamide A and B

8. Rynchophylline and Isorynchophylline

9. Spirotryprostatin A

10. (‒)-Spirotryprostatin B

11. Strychnofoline

Detalles del producto

  • Edición: 1
  • Última edición
  • Publicado: 4 de febrero de 2022
  • Idioma: Inglés

Sobre los autores

MU

Maliha Uroos

Dr. Maliha Uroos completed her PhD in synthetic organic chemistry in 2012 from the University of Nottingham under HEC Faculty Development Scholarship. She was awarded EPSRC post-doctoral fellowship (2012-13) at the University of Nottingham, UK. She was appointed Lecturer at University of the Punjab in 2007 and currently working as Associate Professor (2020 to date) and Director, Centre for Research Ionic Liquid, School of Chemistry, University of the Punjab. Her main focus is synthetic organic chemistry and research interests include synthesis and applications of ionic liquids, synthesis of biologically active molecules, sustainable energy production and development of green processes for setting up bio-refinery from agricultural waste.
Afiliaciones y experiencia
Associate Professor and Director, Centre for Research Ionic Liquid, School of Chemistry, University of the Punjab, Pakistan

AH

Abdul Hameed

Dr. Abdul Hameed Dr. Abdul Hameed completed his PhD in Organic Chemistry from The University of Nottingham, UK. He worked in the area of natural products synthesis. He was a post-doc fellow in Max-Planck Institut für Polymerforschung, Germany in synthetic division headed by Prof. Dr. Klaus Müllen. There he worked on the functionalization of adenylyl cyclsase inhibitors via chemical methods to conjugate them with monoclonal antibody to study their biological potential in Regulatory T cells (Treg). His current research interests are including the development of novel methodologies, their utilization in natural products synthesis, the synthesis heterocyclic compound compounds to evaluate their biological potential.
Afiliaciones y experiencia
Department of Chemistry, University of Sahiwal, Sahiwal, Pakistan

SN

Sadia Naz

Sadia Naz is currently a PhD student at Centre for Research Ionic Liquid, School of Chemistry, University of the Punjab (2018 to onwards) and is working as research assistant in HEC NRPU project with Dr. Maliha Uroos (2019 to onwards). She has publications in international journals and presented her work in various international and national conferences. Her research interests include synthetic organic chemistry, ionic liquids, conversion of agricultural waste materials into valuable platform chemicals.
Afiliaciones y experiencia
Centre for Research Ionic Liquid, School of Chemistry, University of the Punjab, Pakistan

MS

Muhammad Raza Shah

Prof. Muhammad Raza Shah is Professor at the International Center for Chemical and Biological Sciences (ICCBS), University of Karachi, Pakistan. His research focuses on nanotechnology, materials science, supramolecular chemistry, nanomedicine, and advanced drug delivery systems, with particular emphasis on nanocarriers for targeted therapeutic applications. He has made significant contributions to the development of novel biomedical and pharmaceutical technologies and holds multiple national and international patents. Prof. Shah has authored and edited several scholarly books and contributed extensively to the scientific literature. He has supervised a large number of postgraduate researchers and maintains active international research collaborations. He is a Fellow of the Pakistan Academy of Sciences and the Islamic World Academy of Sciences and has received national recognition for his contributions to chemical sciences.
Afiliaciones y experiencia
Professor, International Center for Chemical and Biological Sciences, H.E.J. Research Institute of Chemistry University, Karachi, Pakistan

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