International Review of Cell and Molecular Biology

Chapter One: New Insights Into Roles of Ubiquitin Modification in Regulating Plastids and Other Endosymbiotic Organelles

• Abstract
• 1. Introduction
• 2. Ubiquitin–Proteasome System
• 3. Regulation of Endosymbiotic Organelles by Ubiquitin
• 4. Concluding Remarks
• Acknowledgments

Chapter Two: New Insights Into the Role of Ubiquitylation of Proteins

• Abstract
• 1. Introduction
• 2. Protein Ubiquitylation
• 3. New Insights Into Noncanonical Ubiquitylation
• 4. New Insights Into Chain Formation and Unconventional Ubiquitin Chains
• 5. Crosstalk Between Ubiquitin and Other Posttranslational Modifications
• 6. New Tools and Developments for Ubiquitylation Studies
• 7. Concluding Remarks
• Acknowledgments

Chapter Three: Heterogeneity, Cell Biology and Tissue Mechanics of Pseudostratified Epithelia: Coordination of Cell Divisions and Growth in Tightly Packed Tissues

• Abstract
• 1. Introduction
• 2. Apical Nuclear Migration in Pseudostratified Epithelia
• 3. Tissue-Wide Properties of PSE
• 4. Conclusions
• Acknowledgments

Chapter Four: New Insight Into the Roles of Membrane Microdomains in Physiological Activities of Fungal Cells

• Abstract
• 1. Introduction: History of Lateral Microdomains in Fungal Membranes
• 2. Contemporary List of Fungal Membrane Microdomains
• 3. Formation and Maintenance of Membrane Microdomains
• 4. Physiological Relevance of Laterally Segregated Membrane Contents
• 5. Concluding Remarks and Perspectives
• Acknowledgments

Chapter Five: Development and Application of Functionalized Protein Binders in Multicellular Organisms

• Abstract
• 1. Introduction
• 2. Protein Binder Scaffolds
• 3. Use of Protein Binders in Basic Science
• 4. Use of Protein Binders in Multicellular Organisms
• 5. Conclusions and Outlook
• Acknowledgment

Chapter Six: Heparan Sulfate: Biosynthesis, Structure, and Function

• Abstract
• 1. Introduction
• 2. Heparan Sulfate Proteoglycans
• 3. Biosynthesis of Heparan Sulfate
• 4. Genetic Defects in Heparan Sulfate
• 5. Structural Properties of Heparan Sulfate in Interaction With Proteins
• 6. Heparan Sulfate Proteoglycans and Diseases
• 7. Therapeutical Potential
• 8. Concluding Remarks
• Acknowledgments

Chapter Seven: Functions of Heparan Sulfate Proteoglycans in Development: Insights From Drosophila Models

• Abstract
• 1. Introduction
• 2. Glypicans
• 3. Syndecan and Perlecan
• 4. Heparan Sulfate Biosynthesis
• 5. Concluding Remarks