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Mesenchymal Stem Cells and Extracellular Vesicles as Next-Generation Therapeutics

Basic Concepts, Clinical Applications, and Cross-Disciplinary Innovations

  • 1 Edición - 24 de junio de 2026
  • Última edición
  • Editores: Naresh Kasoju, Ramesh Bhonde
  • Idioma: Inglés

Mesenchymal Stem Cells and Extracellular Vesicles as Next-Generation Therapeutics: Basic Concepts, Clinical Applications, and Cross-Disciplinary Innovations provides a compre… Leer más

Descripción

Mesenchymal Stem Cells and Extracellular Vesicles as Next-Generation Therapeutics: Basic Concepts, Clinical Applications, and Cross-Disciplinary Innovations provides a comprehensive exploration of the groundbreaking roles stem cells and extracellular vesicles (EVs) play in regenerative medicine. The book examines the fundamental biology of stem cells and EVs, their therapeutic applications across tissues - including skin, neural, cardiac, ocular, and more and the innovative, interdisciplinary approaches shaping the future of healthcare. Sections cover Basic and Emerging Concepts, Therapeutic Applications and Disease Focus, and Cross-disciplinary Innovations and Future Directions the field will encounter in this rapidly growing branch of medicine.

Written by experts in the field for researchers and academics engaged in regenerative medicine, stem cell biology, and biomedical engineering, this book will be of interest to healthcare professionals such as physicians, surgeons, and specialists interested in tissue repair and regeneration.

Puntos claves

  • Integrates knowledge from bioengineering, nanotechnology, and artificial intelligence, offering innovative perspectives for advancing regenerative medicine
  • Provides practical applications, thus empowering researchers and practitioners to make informed decisions and drive innovation in tissue regeneration
  • Includes case studies that demonstrate how theoretical concepts translate into tangible therapies, providing actionable insights for healthcare professionals and industry practitioners

De interès para

Researchers and academics in regenerative medicine, stem cell biology, and biomedical engineering, as well as healthcare professionals such as physicians, surgeon and those specializing in tissue repair and regeneration

Índice

SECTION I: Basic and emerging concepts

1 Introduction to mesenchymal stem cells and extracellular vesicles as next-generation therapeutics
Naresh Kasoju, Ramesh Bhonde

2 Introduction to mesenchymal stem cell and extracellular vesicle biology
Ganga Anand, Manoj Komath, Madhusoodanan Urulangodi

3 An overview on mesenchymal stem cells and extracellular vesicles in regenerative medicine
Meenakshi Mendiratta, Mayank Kashyap, Sujata Mohanty

4 Engineering extracellular vesicles and mesenchymal stem cells for enhanced organ retention
Muskaan Belani, Sarita Sharadchandra Gupta

5 Biomanufacturing of mesenchymal stem cells and extracellular vesicles: challenges and advances in isolation, scale-up, storage, transportation, and beyond
Avinash Haribhau Kharat, Ramesh Bhonde

6 Quality, commercialization, and equity in mesenchymal stem cell and extracellular vesicle therapies
Madhan Jeyaraman, Naveen Jeyaraman, Swaminathan Ramasubramanian, Arulkumar Nallakumarasamy

7 Regulatory pathways for mesenchymal stem cell and extracellular vesicle-based therapies: comparative perspectives from India, Europe, and the United States
Amrutha C., Mahima R.
SECTION II: Therapeutic applications and disease focus

8 Mesenchymal stem cells and extracellular vesicles in skin regeneration
Reshma Murali, Anugya Bhatt

9 Mesenchymal stem cells and extracellular vesicles in neural regeneration
Gayathri P.S., Sreelekshmi B.S., Geethu S. Nair, Divya M.S.

10 Mesenchymal stem cells and extracellular vesicles in neurodegenerative diseases
Praveena Ganji, Meghana Hanagodu, Prasad G. Rao, Dharshitha Varigonda, Subhashini Prabhakar, Sasidhar Manda Venkata

11 Mesenchymal stem cells and extracellular vesicles in cardiac regeneration
R. Dhanya, Neethu Mohan

12 Mesenchymal stem cells and extracellular vesicles in ocular regeneration
Naresh Kasoju, Shyama Sukumaran Nair, Varsha Anilkumar Mayadevi

13 Mesenchymal stem cells and extracellular vesicles in bone regeneration
Saranya S.S., Heba Baby, Francis B. Fernandez

14 Mesenchymal stem cells and extracellular vesicles in cartilage regeneration
Amrita Natarajan, Anjali Sudha, Aswathy Jalaja

15 Mesenchymal stem cells and extracellular vesicles in liver regeneration
Khushi Karnawat, Neethu Puthiyattil, Rithika Parthasarathy, Anupama Sekar J., Priyanka Elangbam, Nabanita Roy, Kapish Gupta, Gowri Manohari Balachander, Roopesh R. Pai

16 Mesenchymal stem cells and their extracellular vesicles in pancreatic regeneration
Bhawna Chandravanshi, Nishant Mante

17 Mesenchymal stem cells and extracellular vesicles in lung regeneration
Monique Martins Melo, Renata Trabach Santos, Johnatas Dutra Silva

18 Mesenchymal stem cell-derived extracellular vesicles in cancer immunotherapy
Arka Sanyal, Vinith Johnson, Uday Kumar S.
SECTION III: Cross-disciplinary innovations and future directions

19 Biomaterials in mesenchymal stem cell and extracellular vesicle research
Banani Kundu

20 Bioreactors in mesenchymal stem cells and extracellular vesicles for therapeutic applications
Avinash Purushottam Sanap, Ramesh Bhonde, Avinash Haribhau Kharat

21 Nanotechnology in mesenchymal stem cell and extracellular vesicle research
Nasera Rizwana, Kaustubh Raundal, D.A. Sanjana, M. Vaishnavi, Manasa Nune

22 Microfluidics in mesenchymal stem cell and extracellular vesicle research
Arjun Jayachandran, Avinash Kotkar, Ganji Praveena, Sachin Chandankar, Sasidhar Manda Venkata, Amit Asthana

23 Artificial intelligence and machine learning in mesenchymal stem cell and extracellular vesicle research
Triptish Bhattacharjee, Ayona Gupta, Uttara Chakraborty

24 Mesenchymal stem cells derived extracellular vesicles in radiation response
Parichita Mishra, Bhisham Narayan Singh, Kamalesh Dattaram Mumbrekar

25 Mesenchymal stem cells and extracellular vesicles in space medicine
Naresh Kasoju, Sujata Mohanty, Ramesh Bhonde

Detalles del producto

  • Edición: 1
  • Última edición
  • Publicado: 25 de junio de 2026
  • Idioma: Inglés

Sobre los editores

NK

Naresh Kasoju

Dr. Naresh Kasoju is a Scientist at Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala. He obtained his Ph.D. in Biotechnology from Indian Institute of Technology and postdoctoral experience from Institute of Macromolecular Chemistry, Prague, Czech Republic and University of Oxford, Oxford, UK. His research interests include mesenchymal stem cells-based therapeutics for regenerative medicine, natural polymers-based biomaterials for biomedical applications, and 3D bioprinting based approaches for tissue engineering. He filed 06 Indian patents and 03 Indian design registrations and has published 70+ articles, with 4500+ citations. He's editor of 3 books, guest editor for 3 special issues, editorial board member for 2 journals and reviewer for 50+ journals. He's a member of National Academy of Science, India and Royal Society of Biology, UK. Recently, he received Young Scientist Award by Indian Academy of Biomedical Sciences, Lucknow for his outstanding contributions in biomaterials, stem cells and tissue engineering.
Afiliaciones y experiencia
Deputy Quality Manager, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, India

RB

Ramesh Bhonde

Dr. Ramesh Bhonde joined Dr D Y Patil University, Pune, as Director (Research) in September 2016. Prior to that he served as Professor & Dean, at the School of Regenerative Medicine, Bangalore for the last 5 years. He retired from National Center for Cell Science Pune as Scientist ‘F’ and joined Stempeutics Research Pvt. Ltd. Bangalore as Technical Director, moving to Stempeutics Research Malaysia branch in Kuala Lumpur, Malaysia. He’s worked in the field of pancreatic regeneration in diabetes for the past 25 years. His areas of interest and expertise include stem cells, regenerative biology, tissue banking and engineering, with special reference to the cultivation of fastidious cells such as hepatocytes, vascular endothelial cells, and islets of Langerhans. He’s well trained in hESC and iPS technology. Dr. Bhonde authored 7 book chapters, and is a recipient of Dr. TMA Pai Endowment Chair in Islet Engineering & Banking in October 2013.

Afiliaciones y experiencia
Director, Research, Dr D Y Patil University, Pune, India