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Elsevier

Microbiome-Modulating Strategies in Diabetic Wound Healing

  • 1 Edición - 1 de mayo de 2027
  • Última edición
  • Editores: Jeena Gupta, Ashish Vyas, Pranav Kumar Prabhakar
  • Idioma: Inglés

Microbiome-Modulating Strategies in Diabetic Wound Healing provides researchers with an in-depth analysis of the wound microbiome’s role in diabetic foot ulcers and chronic woun… Leer más

Descripción

Microbiome-Modulating Strategies in Diabetic Wound Healing provides researchers with an in-depth analysis of the wound microbiome’s role in diabetic foot ulcers and chronic wound pathology. This reference elucidates microbial dysbiosis, biofilm formation, and host–microbe interactions that exacerbate impaired healing in diabetic patients. It critically evaluates emerging microbiome-targeted interventions—including probiotics, bacteriophages, antimicrobial peptides, and nanotechnology-enabled drug delivery—supported by the latest molecular, microbiological, and clinical research. The book integrates advanced diagnostic methodologies such as next-generation sequencing and bioinformatics to facilitate precise microbial profiling and personalized therapeutic design. By bridging mechanistic insights with translational and clinical evidence, this resource equips diabetic researchers with comprehensive knowledge to innovate and optimize microbiome-based strategies, ultimately aiming to reduce infection rates, combat antibiotic resistance, and improve regenerative outcomes in diabetic wound management.

Puntos claves

  • Provides a detailed exploration of probiotics, prebiotics, phage therapy, antimicrobial peptides, and nanotechnology-driven interventions tailored for diabetic wounds
  • Presents an interdisciplinary approach to appeal to both laboratory researchers and clinicians by combining molecular biology, microbiology, immunology, and clinical wound management perspective
  • Includes advanced microbiome profiling techniques, including next-generation sequencing and bioinformatics, to inform therapy design

De interès para

Biomedical researchers specializing in endocrinology, diabetes, microbiology, immunology, and wound healing, wound care specialists managing diabetic ulcers Diabetologists interested in complications and integrative therapies

Índice

1. Introduction to Diabetic Wounds and Healing Challenges

2. The Wound Microbiome: Composition and Dynamics

3. Microbial Dysbiosis in Diabetic Wounds

4. Biofilms and Chronic Infections in Diabetes DFUs

5. Diagnostic Techniques for Wound Microbiome Profiling

6. Antibiotic Resistance and Limitations in Current Treatments

7. Probiotic and Prebiotic Therapies in Diabetic Wound Healing

8. Bacteriophage and Enzybiotic Approaches

9. Fecal and Skin Microbiota Transplants

10. Peptide-Based and Nanotechnology-Driven Microbiome Modulators

11. Host-Directed Therapies and Immunomodulation for Diabetic Patients

12. Regulatory and Ethical Aspects of Microbiome Therapeutics

13. Clinical Trials, Outcomes, and Meta-Analysis

14. Future Perspectives: Personalized Microbiome Therapies for Diabetic Wounds

Detalles del producto

  • Edición: 1
  • Última edición
  • Publicado: 1 de mayo de 2027
  • Idioma: Inglés

Sobre los editores

JG

Jeena Gupta

Dr. Jeena Gupta is a faculty member at Lovely Professional University, Punjab, India, with over 20 years of research experience in epigenetics and diabetes. Her research encompasses metabolic memory, chronic diseases, phyto-nanomedicine for diabetes, wound healing, breast cancer, and epigenetic regulatory mechanisms, including histone post-translational modifications in regulating gene expression in diabetes and its associated complications. Dr. Gupta is an active member of several professional societies and serves on the editorial reviewer board for the Frontiers Journal of Endocrinology. She continues to contribute to her field through research, teaching, and academic service.

Afiliaciones y experiencia
Lovely Professional University, India

AV

Ashish Vyas

Professor Ashish Vyas is an academic leader with 20+ years of experience, dedicated to fostering research, education, and institutional growth. Dr. Vyas is presently the Director of the Saraswati Group of Colleges, Mohali, Punjab. He was Formerly the Head, Department of Microbiology and Biochemistry Lovely Professional University, Punjab, India. His area of expertise and research Interests includes Fermentation Technology and Microbial Enzymes, Biocontrol Strategies for Plant Pathogens, Microbial Pigments and Green Nano Synthesis, Bioinformatics and Bioprocess Engineering. His academic and research experience spans 20+ years of teaching and research publishing 65+ research papers and authoring 10+ book chapters. He has supervised 11 Ph.D and 5 MPhil scholars. He has been awarded 3 international patents(granted), 7 patents(published) and 5 copyrights (granted). Prof. Vyas has also served as Advisory Board Member and delivered Invited lectures in multiple national and international conferences along with a grant from Department of Biotechnology Government of India for International Conferences.
Afiliaciones y experiencia
Director, Saraswati Group of Colleges, Mohali, Punjab, India

PP

Pranav Kumar Prabhakar

Pranav Kumar Prabhakar is Professor and Head of the Department of Biotechnology, School of Engineering and Technology, Nagaland University, Kohima, India. His research focuses on understanding molecular mechanisms involved in metabolic disorders, particularly diabetes, and on developing strategies for oral insulin delivery using natural products and biotechnology-based approaches. He is actively involved in research, academic mentoring, peer review, and editorial activities within the biomedical and biotechnology fields. His professional interests include translational research, signaling pathways associated with metabolic diseases, and the application of biotechnology to improve therapeutic outcomes. He contributes to scientific and academic initiatives that support advancements in biotechnology and healthcare research.

Afiliaciones y experiencia
Professor & Head, Department of Biotechnology, School of Engineering and Technology, Nagaland University, Meriema, Kohima, Nagaland, India