Saltar al contenido principal
Elsevier

Nanocarriers for Drug-Targeting Brain Tumors

  • 1 Edición - 21 de junio de 2022
  • Última edición
  • Editores: Lalit Kumar, Yashwant Pathak
  • Idioma: Inglés

Nanocarriers for Drug-Targeting Brain Tumors covers different types of nanocarriers and  their design and development for targeting drugs to the brain. The book also presents case… Leer más

Descripción

Nanocarriers for Drug-Targeting Brain Tumors covers different types of nanocarriers and their design and development for targeting drugs to the brain. The book also presents case studies and the mechanism of action of nanocarriers in drug targeting to a specific site. This helps researchers and clinicians understand the design, development and mechanism of action of nanocarriers. As brain tumors continue to be a significant health problem globally, and very complex for targeting drugs, conventional dosage forms are not very effective and side-effects are a major concern. Functionalized nanocarriers can address these problems.

Furthermore, the targeting of nanocarriers is preferred for reducing toxicity and improving the effectiveness of the drugs. However, there is a need for understanding the design and development of formulation with the mechanism of action of nanocarriers for brain targeting.

Puntos claves

  • Provides information on the design and development of nanocarriers for targeting brain tumors
  • Outlines the working principles of different nanocarriers for targeting brain tumors
  • Includes case studies of different nanocarriers for targeting brain tumors

De interès para

Materials scientists and engineers

Índice

Part A Anatomy and physiology of the brain

1. An overview of the anatomy and physiology of the brain

2. Blood-brain barrier and central nervous system drug delivery: Opportunities and challenges

Part B Pharmacological and clinical problems

3.Challenges in targeting to brain and brain tumors

4. Potential targeting sites in brain and brain tumors

5. Drug resistance problems in chemotherapy

Part C Introduction and biomedical applications of nanocarriers

6. An overview on nanocarriers

7. Biomedical applications of nanocarriers in brain tumor targeting

Part D Lipophilic nanocarriers

8. Solid lipid nanoparticle-based drug delivery for targeting brain tumors

9. Nanostructured lipid carriers as an alternative carrier with high drug loading for targeting to brain tumors

10. Design, development, and mechanism of liposomes in drug targeting to brain tumors

11. Niosomes based drug delivery in targeting brain tumors

12. Nanoemulsions as effective carriers for targeting brain tumors

Part E Polymeric nanocarriers

13. Mechanism of polymeric micelles for drug targeting to brain tumors

14. Dendrimers as carriers for active targeting of brain tumors

15. Multifunctional polymeric nanocarriers for targeting and treatment of brain tumors

16. Polymersomes for targeting to brain tumors

Part F Metallic nanocarriers systems

17. Development and applications of gold nanoparticles for drug targeting to brain tumors

18. Gold nanoparticles in cancer theranostics

19. Targeting of silver nanoparticles to brain tumors

Part G Hybrid nanocarriers

20. Hybrid nanoparticles to cross the blood–brain barrier

21. Targeting of lipid-polymer (hybrid) nanoparticles to brain tumors

22. Nano-enabled systems for neural tissue regenerative applications

23. Multifunctional liposome-quantum dot hybrid nanocarriers for drug targeting to brain tumors

24. Drug-loaded nanoclusters for brain targeting

25. Nano-enabled platforms for tropical diseases affecting the CNS

26. Phytoconstituents in brain delivery using nanodrug delivery

27. Multifunctional nanocarrier systems targeting brain tumors: A review

Part H Future directions and toxic concerns

28. Expert opinion on current challenges and future directions related to nanocarriers for drug targeting to the brain

29. Biological nanodrugs for brain targeting

Detalles del producto

  • Edición: 1
  • Última edición
  • Publicado: 23 de junio de 2022
  • Idioma: Inglés

Sobre los editores

LK

Lalit Kumar

Lalit Kumar is an Assistant Professor in the Department of Pharmaceutics at the National Institute of Pharmaceutical Education and Research, Hajipur, Vaishali, Bihar, India. His area of research includes the development of nanocarriers for drug-targeting tumor cells in the colon, brain, breast, and lungs.
Afiliaciones y experiencia
Assistant Professor, Department of Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal, India

YP

Yashwant Pathak

Yashwant Pathak is a Professor at Taneja College of Pharmacy at the University of South Florida, FL, United States. His area of research is nanotechnology, drug delivery systems, and nutraceuticals. He is also an Ad junct Professor at the Faculty of Pharmacy, Airlangga University, Surabaya, Indonesia.
Afiliaciones y experiencia
College of Pharmacy, University of South Florida, Tampa, FL, USA

Ver libro en ScienceDirect

Lee Nanocarriers for Drug-Targeting Brain Tumors en ScienceDirect