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Poly(lactic-co-glycolic acid) (PLGA) Nanoparticles for Drug Delivery

  • 1 Edición - 2 de marzo de 2022
  • Última edición
  • Editor: Prashant Kesharwani
  • Idioma: Inglés

Poly(lactic-co-glycolic acid) (PLGA) Nanoparticles for Drug Delivery is a comprehensive guide to PLGA nanoparticles for targeting various diseases, covering principles, formation… Leer más

Descripción

Poly(lactic-co-glycolic acid) (PLGA) Nanoparticles for Drug Delivery is a comprehensive guide to PLGA nanoparticles for targeting various diseases, covering principles, formation, characterization, applications, regulations and the latest advances. Sections introduce the fundamental aspects of PLGA nanoparticles for drug delivery, including properties, preparation methods, characterization, drug loading methods, and drug release mechanisms, along with a focus on applications. Application of PLGA nanoparticles for the treatment of cancer, inflammatory, cerebral, cardiovascular, and infectious diseases, as well as in regenerative medicine, photodynamic and photothermal therapy, and gene therapy, are all explained in detail.

The final chapters explore recent advances and regulatory aspects. This book is a valuable resource for researchers and advanced students across nanomedicine, polymer science, bio-based materials, chemistry, biomedicine, biotechnology, and materials engineering, as well as for industrial scientists and R&D professionals with an interest in nanoparticles for drug delivery, pharmaceutical formulations and regulations, and development of innovative biodegradable materials.

Puntos claves

  • Presents the fundamentals of PLGA nanoparticles, including properties, preparation, characterization, and biofate and cellular interactions
  • Provides in-depth coverage of a broad range of specific applications of PLGA nanoparticles across disease treatment, regenerative medicine and therapeutic areas
  • Offers a methodical approach to PLGA nanoparticles in drug delivery that is supported by data tables, illustrative figures and flowcharts

De interès para

Researchers and advanced students in nanoparticles, nanomedicine, polymer science, bio-based materials, chemistry, biomedicine, biotechnology, and materials engineering, Scientists, R&D professionals, and clinicians with an interest in pharmaceutical formulations and regulations, and development of innovative plant-derived materials

Índice

PART A Synthesis and characterization of PLGA nanoparticles for drug delivery

1. History, introduction, and properties of PLGA nanoparticles as drug delivery carriers
Gulsel Yurtdas¸ Kirimlio>glu

2. Preparation and characterization of PLGA nanoparticles
Raphaël Cornu, Gautier Laurent, and Arnaud Beduneau

3. Drug loading methods and mechanism of drug release from PLGA nanoparticles
Gulsel Yurtdas¸ Kirimlio>glu

4. Biofate and cellular interactions of PLGA nanoparticles
Letícia Bueno Macedo, Cristiane Franco Codevilla, Daniela Mathes, Bianca Costa Maia,
Clarice Madalena Bueno Rolim, and Daniele Rubert Nogueira-Librelotto

PART B Application of PLGA nanoparticles in drug delivery

5. Targeting strategies using PLGA nanoparticles for efficient drug delivery
Priyanka Sharma, Navneet Kaur, and Asifkhan Shanavas

6. Current progress in PLGA-based nanoparticles for treatment of cancer diseases
Irem Karasu, Sedenay Akbas¸, and Yılmaz Çapan

7. PLGA-based nanoparticles for enhanced diagnosis and cancer therapy
Archana Kumari, Arijit Mal, Roly Yogendra Kaushik, and Rajdip Bandyopadhyaya

8. PLGA-based nanoparticles for the treatment of inflammatory diseases
Deepti Singh, Mohammad Afsar Khan, and Hifzur R. Siddique

9. PLGA-based nanoparticles for treatment of cerebral diseases
Juna Brigit Chacko and Sajan Jose

10. PLGA-based nanoparticles for treatment of cardiovascular diseases
JulyanaNoval de Souza Ferreira, VannylaViktória Viana Vasconcelos, Barbara Silva Figueiredo,
Demian Paiva Alves, Antony Luca Luna Vieira de Abreu, Priscila Ponate de Souza,
Dayana Laura Nascimento Costa, and Andre Romero da Silva

11. PLGA-based nanoparticles for treatment of infectious diseases
Johannes Buescher, Armin Walter Novak, Saeed Ahmed Khan, Agnes-Valencia Weiß, Sangeun Lee, and Marc Schneider

12. PLGA-based nanoparticles as regenerative medicine
Deepika Sharma, Smruti Rekha Rout, Gowtham Kenguva, Mahender Khatravath, Gaurav K. Jain, Geeta Aggarwal, Prashant Kesharwani, and Rambabu Dandela

13. Photodynamic and photothermal therapy using PLGA nanoparticles
Deepak Dinakaran, Abul Kalam Azad, and Brian C. Wilson

14. Gene therapy using PLGA nanoparticles
Smruti Rekha Rout, Gowtham Kenguva, Deepika Sharma, Amirhossein Sahebkar, Vidhu Aeri, Prashant Kesharwani, and Rambabu Dandela

PART C Recent advances and regulatory aspects in PLGA nanoparticles

15. Hybrid PLGA nanoparticles as advanced drug delivery and theranostic applications
Hayrettin Tonbul and Yılmaz Çapan

16. Clinical translation of PLGA nanoparticles into the market
Khushboo Jani and Neeraj Kaushal

17. Biological toxicity and environmental hazards associated with PLGA nanoparticles
Zachary R. Stromberg, Daniel E. Jacobsen, Philip A. Kocheril, and Jessica Z. Kubicek-Sutherland

18. PLGA nanoparticles: Current uses and emerging trends
Itaciara Larroza Nunes, Flávia Barbosa Schappo, Larissa Santos Assuncão, and Camila Duarte Ferreira Ribeiro

Detalles del producto

  • Edición: 1
  • Última edición
  • Publicado: 2 de marzo de 2022
  • Idioma: Inglés

Sobre el editor

PK

Prashant Kesharwani

Dr. Prashant Kesharwani is an Assistant Professor of Pharmaceutics at Dr. Harisingh Gour Vishwavidyalaya (A Central University), Sagar, India. His work focuses on translational nanomedicine, polymeric biomaterials, targeted drug delivery, nanoengineered drug delivery systems, and translational pharmaceutical research. He has contributed extensively to the scientific literature and has served as an editor of scholarly books. Dr. Kesharwani has received research funding from national agencies and has been recognized with awards and fellowships for his contributions to the field. His research interests include nanomedicine, targeted and stimuli-responsive drug delivery, polymeric nanocarriers, and related pharmaceutical applications. He is actively involved in scientific research, academic mentoring, and scholarly publishing.

Afiliaciones y experiencia
Dr. Harisingh Gour Vishwavidyalaya University, India

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