Precision Care in Gastroesophageal Reflux Disease

Using Pathophysiology and Clinical Insights towards a Personalized Approach

1 Edición - 1 de marzo de 2027
Última edición
Editores: Walter W. Chan, Prakash Gyawali
Idioma: Inglés

Precision Care in Gastroesophageal Reflux Disease: Using Pathophysiology and Clinical Insights towards a Personalized Approach addresses the urgent need for personalized approa… Leer más

Descripción

Precision Care in Gastroesophageal Reflux Disease: Using Pathophysiology and Clinical Insights towards a Personalized Approach addresses the urgent need for personalized approaches in managing GERD. This reference explores the evolving understanding of GERD pathophysiology and the necessity to move beyond generalized treatments toward disease phenotyping and targeted therapy. It emphasizes integrating clinical insights with emerging diagnostic technologies to optimize patient outcomes. The book’s content is organized into sections covering disease phenotypes and pathophysiology, clinical presentation, diagnostic techniques, and management approaches. Chapters include detailed discussions on symptom mechanisms, hypervigilance, diagnostic endoscopy, esophageal function testing, and both medical and surgical treatment options. Contributions from international experts provide evidence-based perspectives on utilizing scoring systems, ancillary tests, and adjunctive therapies to support precision care. Precision Care in Gastroesophageal Reflux Disease equips clinicians, advanced practice providers, and trainees with state-of-the-art knowledge to tailor evaluation and treatment strategies for diverse GERD phenotypes. It is an essential resource for those seeking to apply precision medicine principles in gastroenterology, enhancing diagnostic accuracy and therapeutic effectiveness in clinical practice.

Puntos claves

Explains GERD pathophysiology influencing clinical evaluation and management
Highlights cutting-edge diagnostics for precision GERD phenotyping
Integrates clinical presentations with diagnostic metrics for personalized care

De interès para

Clinicians managing patients with GERD symptoms

Índice

I. Disease Phenotypes and Pathophysiology

1. Mechanisms of Typical and Atypical Reflux Symptoms

2. Reflux Symptom-Specific Hypervigilance and Hypersensitivity

3. Typical and Atypical GERD Phenotypes

II. Clinical Presentation

4. Clinical History and Patient-Reported Outcome Measures

5. Differential Diagnoses of Typical and Atypical Reflux Symptoms

III. Diagnostic Techniques

6. Endoscopy in the Diagnosis of GERD

7. Esophageal Function Testing for GERD: Reflux Monitoring and Manometry

8. Ancillary Techniques for Typical and Atypical GERD

9. Integration of Clinical and Diagnostic Data: The Value of Clinical Scores and Algorithms in Phenotyping GERD

IV. Management Approaches

10. Medical Therapy of Typical and Atypical Reflux Symptoms

11. Surgical and Invasive Management of GERD

12. Adjunctive and Complementary Approaches to Managing Reflux Symptoms

Detalles del producto

Edición: 1
Última edición
Publicado: 1 de marzo de 2027
Idioma: Inglés

Sobre los editores

Walter W. Chan

Dr. Walter Chan is the Director of the Center for Gastrointestinal Motility at Brigham and Women's Hospital, Director of Clinical Research Education at the Division of Gastroenterology, Hepatology and Endoscopy, and Associate Professor of Medicine at Harvard Medical School in Boston, USA. He is a gastroenterologist specializing in esophageal, gastrointestinal motility, and gut-brain disorders. His academic interests center around understanding the pathophysiology and optimizing the management of esophageal and gastrointestinal motility disorders, particularly in gastroesophageal reflux disease (GERD) and its extraesophageal manifestations. He is an active clinical investigator and has authored over 150 peer-reviewed publications, 22 book chapters, and 200 presentations at major national/international scientific meetings. He currently serves as Associate Editor for two peer-reviewed gastroenterology journals (Digestive Diseases and Science, Diseases of the Esophagus), as well as Section Editor for the ASGE journal iGIE.

Afiliaciones y experiencia

Director of the Center for Gastrointestinal Motility at Brigham and Women's Hospital, Director of Clinical Research Education at the Division of Gastroenterology, Hepatology and Endoscopy, and Associate Professor of Medicine at Harvard Medical School in Boston, USA

Prakash Gyawali

Dr. Prakash Gyawali is Professor of Medicine, and Director of Neurogastroenterology and Motility at the Division of Gastroenterology, Washington University School of Medicine, St. Louis, USA. Dr. Gyawali's academic interests include esophageal motility disorders, gastroesophageal reflux disease, and functional disorders. He directs gastrointestinal motility centers affiliated with Washington Universit and is involved in motility testing using high resolution manometry, esophageal ambulatory esophageal pH and impedance monitoring, wireless pH monitoring and endoscopic functional lumen imaging probe (FLIP). He is actively involved in clinical research involving neurogastroenterology and motility, and has published over 325 original articles, several invited reviews and book chapters. He is an Associate Editor for three peer-reviewed gastroenterology journals (American Journal of Gastroenterology, Diseases of the Esophagus, Dysphagia). He is the editor of two handbooks: four editions for the Washington University Subspecialty Series for Gastroenterology, and A Therapeutic Guide to Common Problems in Gastroenterology.