The Blood–Brain Barrier and Nanomedicine
- 1 Edición - 1 de abril de 2027
- Última edición
- Editor: Prashant Kesharwani
- Idioma: Inglés
The Blood–Brain Barrier and Nanomedicine reviews the development of nanomedicine approaches aimed at crossing the blood–brain barrier (BBB), a significant obstacle in delive… Leer más
Descripción
Descripción
The Blood–Brain Barrier and Nanomedicine reviews the development of nanomedicine approaches aimed at crossing the blood–brain barrier (BBB), a significant obstacle in delivering therapeutic agents to the brain and in treating neurological disorders. Key topics such as the physiology of the BBB, alternative protective strategies, and the blood–tumor barrier are covered, providing a thorough overview of key concepts and challenges. Various nanocarriers - including liposomes, niosomes, dendrimers, and metal-based nanoparticles – are detailed, along with different delivery methods, such as nanoemulsions, nanocrystals, and nose-to-brain delivery. Finally, considerations for toxicity, regulatory approval, and clinical trial design, as well as associated challenges are assessed, providing insights into technological developments and translational hurdles.
The Blood–Brain Barrier and Nanomedicine is of interest to researchers and academics in the fields of materials science, nanotechnology, pharmaceutical science and pharmacology, as well as clinicians with an interest in nanomedicine.
The Blood–Brain Barrier and Nanomedicine is of interest to researchers and academics in the fields of materials science, nanotechnology, pharmaceutical science and pharmacology, as well as clinicians with an interest in nanomedicine.
Puntos claves
Puntos claves
- Details various nanocarriers and delivery methods to enhance drug crossing of the blood–brain barrier
- Discusses toxicity, regulatory considerations, and clinical trial strategies for translating nanomedicine into therapies
- Highlights current challenges and future directions to support research and development of CNS-targeted nanomedicine solutions
De interès para
De interès para
Researchers and academics in the fields of materials science, nanotechnology, pharmaceutical science and pharmacology, as well as clinicians with an interest in nanomedicine
Índice
Índice
1. Impact of the Blood–Brain Barrier (BBB) in Central Nervous System Disorders
2. Alternative Protective Strategies of the Blood–Brain Barrier
3. Understanding the Blood–Tumor Barrier (BTB)
4. Exploiting Blood–Brain Barrier Properties for Effective Nanodelivery
5. Overcoming the Blood–Brain Barrier Using Nanomedicines
6. Nanoemulsions and Nanocrystals in Overcoming the Blood–Brain Barrier
7. Liposomes and Niosomes in Overcoming the Blood–Brain Barrier
8. Nanomicelles in Overcoming the Blood–Brain Barrier
9. Gold Nanoparticles in Overcoming the Blood–Brain Barrier
10. Silver Nanoparticles in Overcoming the Blood–Brain Barrier
11. Iron Oxide Nanoparticles in Overcoming the Blood–Brain Barrier
12. Mesoporous Silica Nanoparticles in Overcoming the Blood–Brain Barrier
13. Metal–Organic Framework-Based Nanomedicine in Overcoming the Blood–Brain Barrier
14. PLGA Nanoparticles in Overcoming the Blood–Brain Barrier
15. Chitosan Nanoparticles in Overcoming the Blood–Brain Barrier
16. Dendrimers in Overcoming the Blood–Brain Barrier
17. Carbon Nano Materials in Overcoming the Blood–Brain Barrier
18. Drug Delivery Approaches from Nose to Brain
19. Overview of Blood–Brain Barrier-Related Clinical Trials
20. Challenges of Delivering Nanomedicines Across the Blood–Brain Barrier
21. Concluding Remarks and Future Outlook for Blood–Brain Barrier-Targeted Therapies
2. Alternative Protective Strategies of the Blood–Brain Barrier
3. Understanding the Blood–Tumor Barrier (BTB)
4. Exploiting Blood–Brain Barrier Properties for Effective Nanodelivery
5. Overcoming the Blood–Brain Barrier Using Nanomedicines
6. Nanoemulsions and Nanocrystals in Overcoming the Blood–Brain Barrier
7. Liposomes and Niosomes in Overcoming the Blood–Brain Barrier
8. Nanomicelles in Overcoming the Blood–Brain Barrier
9. Gold Nanoparticles in Overcoming the Blood–Brain Barrier
10. Silver Nanoparticles in Overcoming the Blood–Brain Barrier
11. Iron Oxide Nanoparticles in Overcoming the Blood–Brain Barrier
12. Mesoporous Silica Nanoparticles in Overcoming the Blood–Brain Barrier
13. Metal–Organic Framework-Based Nanomedicine in Overcoming the Blood–Brain Barrier
14. PLGA Nanoparticles in Overcoming the Blood–Brain Barrier
15. Chitosan Nanoparticles in Overcoming the Blood–Brain Barrier
16. Dendrimers in Overcoming the Blood–Brain Barrier
17. Carbon Nano Materials in Overcoming the Blood–Brain Barrier
18. Drug Delivery Approaches from Nose to Brain
19. Overview of Blood–Brain Barrier-Related Clinical Trials
20. Challenges of Delivering Nanomedicines Across the Blood–Brain Barrier
21. Concluding Remarks and Future Outlook for Blood–Brain Barrier-Targeted Therapies
Detalles del producto
Detalles del producto
- Edición: 1
- Última edición
- Publicado: 1 de abril de 2027
- Idioma: Inglés
Sobre el editor
Sobre el editor
PK
Prashant Kesharwani
Dr. Prashant Kesharwani is an Assistant Professor of Pharmaceutics at Dr. Harisingh Gour Vishwavidyalaya (A Central University), Sagar, India. His work focuses on translational nanomedicine, polymeric biomaterials, targeted drug delivery, nanoengineered drug delivery systems, and translational pharmaceutical research. He has contributed extensively to the scientific literature and has served as an editor of scholarly books. Dr. Kesharwani has received research funding from national agencies and has been recognized with awards and fellowships for his contributions to the field. His research interests include nanomedicine, targeted and stimuli-responsive drug delivery, polymeric nanocarriers, and related pharmaceutical applications. He is actively involved in scientific research, academic mentoring, and scholarly publishing.
Afiliaciones y experiencia
Dr. Harisingh Gour Vishwavidyalaya University, India