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The Chemokine Factsbook

Ligands and Receptors

  • 1 Edición - 1 de abril de 1997
  • Última edición
  • Autores: Krishna Vaddi, Margaret Keller, Matthew Newton
  • Idioma: Inglés

How do you keep track of basic information on the proteins you work with? Where do you find details of their physicochemical properties, amino acid sequences, gene organization? Ar… Leer más

Descripción

How do you keep track of basic information on the proteins you work with? Where do you find details of their physicochemical properties, amino acid sequences, gene organization? Are you tired of scanning review articles, primary papers and databases to locate that elusive fact?

The Academic Press FactsBook series will satisfy scientists and clinical researchers suffering from information overload. Each volume provides a catalog of the essential properties of families of molecules. Gene organization, amino acid sequences, physicochemical properties, and biological activity are presented using a common, easy-to-follow format. Taken together they compile everything you want to know about proteins but are too busy to look for. The Chemokine FactsBook contains more than 40 entries on chemokines, and chemokine receptors from human or other origin, including IL-8, MCP-1, C5-a, RANTES, Lymphotactin, and CC CKR-1.

The text provides information on tissue sources, target cells, physicochemical properties, transcription factors, regulation of expression in disease, receptor-binding characteristics, gene structure and location, amino acid sequences, and accession numbers and references.

Puntos claves

  • Contains over 40 entries on chemokines and chemokine receptors from human or other origin, including:
    • IL-8
    • MCP-1
    • C5-a
    • RANTES
    • Lymphotactin
    • CC CKR-1
  • Entries provide information on:
    • Tissue sources
    • Target cells
    • Physicochemical properties
    • Transcription factors
    • Regulation of expression
    • Expression in disease
    • Receptor-binding characteristics
    • Gene structure and location
    • Amino acid sequences
    • Database accession numbers
    • References

De interès para

Ideal for immunologists, cell biologists, biochemists, molecular biologists, pharmacologists, cancer biologists, developmental biologists, biotechnologists, members of the pharmaceutical industry, and to medical researchers. Potential for bulk sales to pharmaceutical companies.

Índice

Introductory Chapters:Introduction.Organization of the Data.Chemokines, An Overview.Chemokine Families.CXC Chemokines.CC Chemokines.Structural Features of Chemokines.Chemokines as Angiogenic and Angiostatic Agents.Chemokines as HIV Suppressive Factors.Chemokine Receptors, An Overview.Chemokines:CXC or I Family Chemokines: IL-8, MGSA, PF4, NAP-2, IP-10, MIP-2, ENA-78, EMF-1, GCP-2, SDF-1, CC or J Family Chemokines: MCP-1, MCP-2, MCP-3, MIP-1a, MIP-1b, RANTES, I-309, C10, HCC-1, C or K Family Chemokines: Lymphotactin, SCM-1.Chemokine Receptors: XC or I Chemokine Receptors: IL-8 Receptor A, IL-8 Receptor B. CC or J Chemokine Receptors: CC CKR-1, CC CKR-2, CC CKR-3, CC CKR-4. Chemoattractant Receptors: C5a Receptor, FPR. Chemoattractant Receptors: PAF Receptor, DARC.Viral Chemokine Receptors: US28, RCRF3.Orphan Chemokine Receptors: CMK-BRL-1, BLR-1/MDR15, HUMSTR, V28, EBI1.Subject Index.

Detalles del producto

  • Edición: 1
  • Última edición
  • Publicado: 1 de abril de 1997
  • Idioma: Inglés

Sobre los autores

KV

Krishna Vaddi

Afiliaciones y experiencia
Postcript, Inc., Cambridge, Massachusetts, U.S.A.

MK

Margaret Keller

Afiliaciones y experiencia
Children's Hospital of Philadelphia, Pennsylvania, U.S.A.

MN

Matthew Newton

Afiliaciones y experiencia
Orthopaedic Physiotherapy Practitioner & Private Practitioner, Doncaster Royal Infirmary, Doncaster, UK

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