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Elsevier

Libros en Microbiología y Virología

  • Functional Microbial Genomics

    • 1 Edición
    • Volumen 33
    • Inglés
    Functional Microbial Genomics, edited by two leading experts in the field, provides the researcher with an up-to-date collection of articles on post-genome technologies central to studying the function of microorganisms.Since the release of the first complete genome sequence of a free-living organism in 1995, over 100 microbial genomes have been completely sequenced. The advent of new technologies for post-genomic analyses has allowed the rapid exploitation of this genome sequence information, heralding a golden era in microbial research. Functional Microbial Genomics provides in-depth accounts from scientists working with these new technologies explaining both the techniques and the ways in which they have been applied to the study of gene function in different microbial species.Methods in Microbiology is the most prestigious series devoted to techniques and methodology in the field. Established for over 30 years, Methods in Microbiology will continue to provide you with tried and tested, cutting edge protocols to directly benefit your research.

  • The Vaccine Book

    • 1 Edición
    • Barry R. Bloom + 1 más
    • Inglés
    The Vaccine Book provides comprehensive information on the current and future world of vaccines. It reveals the scientific opportunities and potential impact of vaccines, including economic and ethical challenges, problems encountered when producing vaccines, how clinical vaccine trials are designed, and how to introduce vaccines into widespread use. Although vaccines are now available for many diseases, there are still challenges ahead for major diseases such as AIDS, tuberculosis, and malaria. The Vaccine Book is designed for students, researchers, public health officials, and all others interested in increasing their understanding of vaccines.

  • Immunology of Infection

    • 2 Edición
    • Volumen 32
    • Inglés
    Immunology of Infection, 2nd Edition, edited by two leading experts in the field, presents the most appropriate up-to-date experimental approaches in the detail required for modern microbiological research. Focusing on the methods most useful for the Microbiologist interested in analysing host-pathogen relationships, this volume will be essential reading for all researchers working in microbiology, immunology, virology, mycology and parasitology.This new edition of Immunology of Infection provides ready-to-use "recipes", and the latest emerging techniques as well as novel approaches to the tried and tested, established methods included in the successful first edition.Methods in Microbiologyis the most prestigious series devoted to techniques and methodology in the field. Established for over 30 years, Methods in Microbiology will continue to provide you with tried and tested, cutting edge protocols to directly benefit your research.

  • Bacterial Pathogenesis, Part C: Identification, Regulation and Function of Virulence Factors

    • 1 Edición
    • Volumen 358
    • Inglés
    The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today—truly an essential publication for researchers in all fields of life sciences.

  • Histidine Kinases in Signal Transduction

    • 1 Edición
    • Masayori Inouye + 1 más
    • Inglés
    Living cells are constantly sensing environmental changes, and their abilities to sense these changes and adapt to them are essential for their survival. In bacteria, histidine kinases are the major sensors for these environmental stresses, enabling cells to adapt to new growth conditions. Written by leading experts in the field, this book provides an up-to-date and comprehensive review on the structure and function of histidine kinases. It also provides extensive information on the physiological roles of histidine kinases in bacteria and eukaryotes. An an essential reference for cell biologists, microbiologists, molecular biologists, and biochemists interested in signal transduction. Experimental biologists and pharmacologists studying signal transduction systems in living organisms will also find it a valuable research tool.

  • Human Papilloma Viruses

    • 1 Edición
    • Volumen 8
    • D.J. McCance
    • Inglés
    This book describes up-to-date information on the pathogenesis and molecular biology of human papillomaviruses and describes the mechanistic role of the viruses in epithelial cancers. Included in the book are chapters on the epidemiology of human papillomaviruses, the factors that control replication and transcription and the viral proteins, which are involved in modulating the biology of the host cell leading to cancer. Details of the immune response to the viruses and potential vaccine strategies are discussed.

  • Recent Advances in Nucleosides: Chemistry and Chemotherapy

    • 1 Edición
    • C.K. Chu
    • Inglés
    The book covers up-to-date information on nucleosides and antiviral chemotherapy contributed by the world experts in the field of nucleoside. This book is the result of a meeting honoring Dr. Jack J. Fox, who was one of the pioneers in nucleoside chemistry and chemotherapy. This book consists of 15 excellent chapters in the area, which include topics from recent synthetic methodologies, nucleoside kinase implicated in chemotherapy and drug design, excellent reviews on antiviral agents, nucleoside metabolism/mode of action in parasites, new compounds under clinical and pre-clinical trials, IMPDH inhibitors to review on nucleoside prodrugs.

  • Advances in Applied Microbiology

    • 1 Edición
    • Volumen 51
    • Allen I. Laskin + 2 más
    • Inglés
    Advances in Applied Microbiology offers intensive reviews of the latest techniques and discoveries in this rapidly moving field. The editors are recognized experts and the format is comprehensive and instructive.

  • Advances in Parasitology

    • 1 Edición
    • Volumen 51
    • John R. Baker + 2 más
    • Inglés
    First published in 1963, Advances in Parasitology contains comprehensive and up-to-date reviews in all areas of interest in contemporary parasitology. Now edited by J.R. Baker (Royal School of Tropical Medicine and Hygiene, UK), R. Muller (International Institute of Parasitology, UK) and D. Rollinson (The Natural History Museum, UK), supported by an international Editorial Board, Advances in Parasitology includes medical studies on parasites of major influence, such as typanosomiasis and scabies, and reviews of more traditional areas, such as zoology, taxonomy, and life history, which shape current thinking and applications. Eclectic volumes are supplemented by thematic volumes on such topics as Remote Sensing and Geographical Information Systems in Epidemiology. In 1999, the Institute for Scientific Information released figures showing that Advances in Parasitology has an Impact Factor of 4.913, placing it 2nd in the highly competitive category of Parasitology.

  • Advances in Virus Research

    • 1 Edición
    • Volumen 58
    • Inglés
    This latest volume in the Advances in Virus Research series presents articles on topics such as the role of lipid rafts in virus assembly and budding; novel vaccine strategies; treatment of arenavirus infections; the evaluation of drug resistance in HIV infection; perspectives on polydnavirus origin and evolution; bateriophage 29 DNA packaging; the potential of plant viral vectors and transgenic plants for subunit vaccine production; and the interaction of orthopoxviruses with interferon-treated cultured cells. This timely and informative compilation of articles will be of interest to researchers in the fields of virology, immunology, microbiology, and plant science.

  • Bioenergetics

    • 3 Edición
    • David G. Nicholls + 1 más
    • Inglés
    This new edition of Bioenergetics presents a clear and up-to-date explanation of the chemiosmotic theory and covers mitochondria, bacteria, and chloroplasts. It takes account of the many newly determined structures, such as ATP synthase and the two photosystems of photosynthesis, that provide molecular insight into chemiosmotic energy transduction. This edition includes additional color figures of protein structures and many newly drawn illustrations designed to enable the reader to grasp the fundamental insights that are derived from knowing the structure. Every chapter has been extensively revised and updated and a new chapter on the study of the bioenergetics of mitochondria in the intact cell is included to satisfy the enormous interest in this topic. Written for students and researchers alike, this book is the most current text on the chemiosmotic theory and membrane bioenergetics available.

  • Guide to Yeast Genetics and Molecular Cell Biology, Part B

    • 1 Edición
    • Volumen 350
    • Inglés
    This volume and its companion, Volume 351, are specifically designed to meet the needs of graduate students and postdoctoral students as well as researchers, by providing all the up-to-date methods necessary to study genes in yeast. Procedures are included that enable newcomers to set up a yeast laboratory and to master basic manipulations. Relevant background and reference information given for procedures can be used as a guide to developing protocols in a number of disciplines. Specific topics addressed in this book include basic techniques, making mutants, genomics, and proteomics.

  • Adenoviral Vectors for Gene Therapy

    • 1 Edición
    • David T. Curiel + 1 más
    • Inglés
    Adenoviral Vectors for Gene Therapy provides detailed and comprehensive coverage of these important therapeutic agents. The topics covered in this book range from the basic biology of adenoviruses, through the construction and purification of adenoviral vectors, cutting-edge vectorology and the use of adenoviral vectors in preclinical animal models, to regulatory issues which must be considered prior to the initiation of human clinical gene therapy trials. The broad scope of this unique volume provides the reader with a complete understanding of the development and use of adenoviral vectors.

  • Agriculture and Food Production

    • 1 Edición
    • Volumen 2
    • Inglés
    This volume of Applied Mycology and Biotechnology completes the set of two volumes dedicated to the coverage of recent developments on the theme "Agriculture and Food Production". The first volume provided overview on fungal physiology, metabolism, genetics and biotechnology and highlighted their connection with particular applications to food production. The second volume examines various specific applications of mycology and fungal biotechnology to food production and processing. In the second volume coverage on two remaining areas of the theme, food crop production and applications in the foods and beverages sector, is presented.The interdisciplinary and complex nature of the subject area, combined with the need to consider the sustainability of agri-food practices, its economics and industrial perspectives, requires a certain focus and selectivity of subjects. In this context the recent literature contained in this work will help readers arrive at comprehensive, in depth information on the role of fungi in agricultural food and feed technology.As a professional reference this book is targeted towards agri-food producer research establishments, government and academic units. Teachers and students, both in undergraduate and graduate studies, in departments of food science, food technology, food engineering, microbiology, applied molecular genetics and biotechnology will also find this work useful.

  • Biotransformations: Bioremediation Technology for Health and Environmental Protection

    • 1 Edición
    • Volumen 36
    • R.D. Stapleton Jr. + 1 más
    • Inglés
    This volume provides a clear understanding of how microbes, following their degradative processes, contribute maximally to the benefit of mankind through biotransformations of waste materials as well as a wide variety of health-risk compounds.The book contains twenty four chapters contributed by leading scientists from different parts of the world, covering various aspects of bioremediation of xenobiotics such as toxic, carcinogenic, teratogenic, and mutagenic compounds, which include halogenated aromatics, derivatives of heavy metals, microbial toxins, tannins, dyes, sulfur compounds of coal and petroleum and pesticides. The bioremediation of agricultural residue, industrial as well as municipal wastes, fuel oils, lubricants, natural rubber products, and other synthetic polymers, which pollute the environment substantially, also constitutes an important component of the book. All biotechnological aspects of microbial transformations pertaining to biodegradation/biore... of hazardous wastes, ranging from screening methods for microbes with degradative potential, processes of degradation, strain improvement for enhanced biodegradation and elimination of xenobiotics of health and environmental concern have been dealt with. The book intends to widen the scope of Applied Microbiology and Biotechnology in general and biotransformations in particular. It will provide an opportunity for scientists in the areas of biochemistry, food industry, environmental science and engineering and their implications in technologically feasible, environment friendly and economically viable bioremediation options. Also, it forms an interface between agro-industrial establishments and the academic world and will generate new thought provoking ideas for scientists of future generations for the safeguard of both human and animal health as well as the environment.

  • Wine Tasting

    A Professional Handbook
    • 1 Edición
    • Ronald S. Jackson
    • Inglés
    One of the most respected professionals in the wine industry-Ron Jackson, author of Wine Science (now in its second edition)- covers all practical and theoretical aspects of wine tasting in his new book. It details the basic techniques used by professionals to sense all visual, gustatory, and olfactory wine properties (sight, taste, and smell). It also describes the physiologic, psychologic, and physicochemical origins of sensory perception and discusses wine types to illustrate the characteristic features that distinguish the majority of wines. A large portion of the book is dedicated to the practical concerns of preparing and performing wine assessments. Readers are instructed in how to differentiate between the various types of wine tastings (each requiring its own design, tasting sheets, training, skill measurement, and analysis). Included is a general overview of the types and sources of wine quality and how wine is most appropriately paired with food. Special features include a flow chart of wine tasting steps, details of errors to avoid, procedures for training and testing sensory skills, sample tasting sheets, original data from 14+ years of training tasters, and numerous tables, charts, and figures.

  • Viruses and Human Disease

    • 1 Edición
    • Ellen G. Strauss + 1 más
    • Inglés
    This is the first text to examine the connection between virology and human disease. It is also the first book to integrate basic virology with pathophysiological conditions. By contrast, most virology textbooks focus on the molecular biology involved without adequate reference to physiology. Viruses and Human Disease is four-color throughout and contains clearly labeled figures and tables.

  • Molecular Medical Microbiology, Three-Volume Set

    • 1 Edición
    • Max Sussman
    • Inglés
    The molecular age has brought about dramatic changes in medical microbiology, and great leaps in our understanding of the mechanisms of infectious disease. Molecular Medical Microbiology is the first book to synthesise the many new developments in both molecular and clinical research in a single comprehensive resource. This timely and authoritative 3-volume work is an invaluable reference source of medical bacteriology. Comprising over 100 chapters, organised into 17 major sections, the scope of this impressive work is wide-ranging.Written by experts in the field, chapters include cutting edge information, and clinical overviews for each major bacterial group, in addition to the latest updates on vaccine development, molecular technology and diagnostic technology.

  • Tumor Suppressing Viruses, Genes, and Drugs

    Innovative Cancer Therapy Approaches
    • 1 Edición
    • Hiroshi Maruta
    • Inglés
    Tumor Suppressing Viruses, Genes, and Drugs profiles the new generation of cancer treatments now in development. The book examines the innovative new approaches of viral, gene, and signal therapies that promise to replace or enhance conventional methods such as surgery, radiation, and chemotherapy. The timely information presented by this book should be of interest to anyone concerned with advancing cancer treatment beyond current medical practices.

  • Advances in Applied Microbiology

    • 1 Edición
    • Volumen 49
    • Inglés
    Advances in Applied Microbiology offers intensive reviews of the latest techniques and discoveries in this rapidly moving field. The editors are recognized experts and the format is comprehensive and instructive. @from:PRAISE FOR THE SERIES @qu:"No laboratory scientist, field worker or technical administrator can afford to pass it up." @source:—ASM NEWS @qu:"The topics are well supported by an extensive bibliography and provide a rich source of current information." @source:—BIOPHARM

  • Plant Virology

    • 4 Edición
    • Roger Hull
    • Inglés
    It has been ten years since the publication of the third edition of this seminal text on plant virology, during which there has been an explosion of conceptual and factual advances. The fourth edition updates and revises many details of the previous editon, while retaining the important older results that constitute the field's conceptual foundation.

  • A Dictionary of Virology

    • 3 Edición
    • Bozzano G Luisa
    • Inglés
    This third edition of A Dictionary of Virology offers an authoritative, concise, and up-to-date list of all viruses affecting vertebrate species, from humans to fish. It has been completely revised since the 1997 edition to include 25% more entries, including many completely new viruses. The entries have been restructured so that all viruses are listed and classified in accordance with the standards set by the 7th Report of the ICTV. The extensive cross-referencing and illustrative tables further enhance the utility of this reference.

  • New Approaches for the Generation and Analysis of Microbial Typing Data

    • 1 Edición
    • L. Dijkshoorn + 2 más
    • Inglés
    Rapid molecular identification and typing of micro-organisms is extremely important in efforts to monitor the geographical spread of virulent, epidemic or antibiotic-resistant pathogens. It has become a mainstay of integrated hospital infection control service. In addition, numerous industrial and biotechnological applications require the study of the diversity of organisms. Conventional phenotypic identification and typing methods have long been the mainstay of microbial population and epidemiological studies, but such methods often lack adequate discrimination and their use is normally confined to the group of organisms for which they were originally devised. Molecular fingerprinting methods have flourished in recent years and many of these new methods can be applied to numerous different organisms for a variety of purposes. Standardisation of these methods is vitally important. In addition, the generation of large numbers of complex fingerprint profiles requires that a computer-assisted strategy is used for the formation and analysis of databases. The purpose of this book is to describe the best fingerprinting methods that are currently available and the computer-assisted strategies that can be used for analysis and exchange of data between laboratories.This book is dedicated to the memory of Jan Ursing (1926 - 2000), Swedish microbiologist, taxonomist and philosopher."...taxo... is on the borders of philosophy because we do not know the natural continuities and discontinuities..."

  • Neurovirology: Viruses and the Brain

    • 1 Edición
    • Volumen 56
    • Inglés
    This volume is the first in a planned series of thematic volumes for Advances in Virus Research. It covers the etiology, pathogenetic mechanisms, and clincial consequences of human neurotropic viruses. Buchmeier is a virologist, Campbell an immunologist, and both are extremely well known in their fields.

  • Advances in Cancer Research

    • 1 Edición
    • Volumen 82
    • Inglés
    Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. Here, once again, outstanding and original reviews are presented on a variety of topics, including nitric oxide-induced apoptosis in tumor cells, detection of minimal residual disease, immunity to oncogenetic human papilloma viruses, and modeling prostate cancer in the mouse.

  • Advances in Microbial Physiology

    • 1 Edición
    • Volumen 45
    • Inglés
    First published in 1967, Advances in Microbial Physiology is one of Academic Press's most renowned and acclaimed series. The Editors have always striven to provide a diverse range of top-quality papers on all aspects of microbial physiology. Coverage of 'holistic' topics or whole cell studies such as ion fluxes, stress responses and motility have gone hand-in-hand with detailed biochemical analyses of individual transport systems, electron transport pathways and many aspects of metabolism. Now edited by Professor Robert Poole, University of Sheffield, Advances in Microbial Physiology continues to publish topical and important reviews, interpreting physiology in its broadest context, to include all material that contributes to our understanding of how microorganisms and their component parts work. In 1999, the Institute for Scientific Information released figures showing that the series has an Impact Factor of 5.35, with a half life of 8 years, placing it 5th in the highly competitive category of Microbiology; testimony to the high regard in which it is held.

  • Microbial Growth in Biofilms, Part A: Developmental and Molecular Biological Aspects

    • 1 Edición
    • Volumen 336
    • Inglés
    This volume and its companion, Volume 337, supplement Volume 310,. These volumes provide a contemporary sourcebook for virtually any kind of experimental approach involving biofilms. They cover bioengineering, molecular, genetic, microscopic, chemical, and physical methods.

  • Marine Microbiology

    • 1 Edición
    • Volumen 30
    • Inglés
    Written by experts in the field, Marine Microbiology presents the latest experimental techniques in the detail required for modern environmental microbiological research. Chapters start with the introduction and background of a particular method, followed by a concise description of the procedures involved. There is also a list of vendors who supply critical components which includes names, addresses, and websites at the end of each chapter.

  • Principles of Molecular Virology (Standard Edition)

    • 3 Edición
    • Alan J. Cann
    • Inglés
    Principles of Molecular Virology, Third Edition provides an essential introduction to modern virology in a clear and concise manner. It is a highly enjoyable and readable text with numerous illustrations that enhance the reader's understanding of important principles. This edition has been updated and revised with new figures and text.

  • Agriculture and Food Production

    • 1 Edición
    • Volumen 1
    • Inglés
    Presenting a stimulating synthesis of rapidly growing research interests and publications by scholars in the field of applied mycology and biotechnology.The surge of research and development activity in applied mycology and fungal biotechnology relates to the need and utility of fungi in many contexts. These contexts are wide in scope, and include agriculture, animal and plant health, biotransformation of organic or inorganic matter, food safety, composition of nutrients and micronutrients, and human and animal infectious disease.Containing a balanced treatment of principles, biotechnological manipulations and applications of major groups of fungi in agriculture and food, this book will serve as a practical resource for mycologists, microbiologists, biotechnologists, bioengineers, scientists from agri-food industry, biochemists, botanists and agriculturists.

  • Principles of Bacterial Pathogenesis

    • 1 Edición
    • Eduardo A. Groisman
    • Inglés
    Principles of Bacterial Pathogenesis presents a molecular perspective on a select group of bacterial pathogens by having the leaders of the field present their perspective in a clear and authoritative manner. Each chapter contains a comprehensive review devoted to a single pathogen. Several chapters include work from authors outside the pathogenesis field, providing general perspectives on the evolution, regulation, and secretion of virulence and determinants.

  • The Fungi

    • 2 Edición
    • Michael J. Carlile + 1 más
    • Inglés
    The fungi are one of the great groups of living organisms, comparable in numbers of species, diversity and ecological significance with animals, plants, protists and bacteria. This textbook deals with all fundamental and applied aspects of mycology, illustrated by reference to well studied species from major fungal groups. Since the publication of the first edition of The Fungi, there have been many important advances in the field of mycology. This second up-to-date edition has been revised and substantially expanded, and incorporates the application of methods of molecular biology, especially DNA technology to mycology.

  • Advances in Immunology

    • 1 Edición
    • Volumen 76
    • Inglés
    Advances in Immunology presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for future research.

  • Advances in Cancer Research

    • 1 Edición
    • Volumen 80
    • Inglés
    Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. Here once again, outstanding and original reviews are presented on a variety of topics including platelet-derived growth factor in disease, genetic predisposition in tumor development, primary effusion lymphoma, and many more.

  • The Neurospora Compendium

    Chromosomal Loci
    • 1 Edición
    • David D. Perkins + 2 más
    • Inglés
    The fungi have been major players in the molecular revolution that has transformed biology. Because they can be manipulated as microorganisms, yeast and Neurospora provide information that is difficult to acquire with plants and animals, and experimental findings with fungi often throw light on corresponding processes in plants and animals. The filamentous fungus Neurospora crassa has become a valuable model organism because of its favorable features for genetic analysis and because of the vast store of information that has been acquired during 75 years of research. This compendium provides researchers and students with a concise account of current knowledge about the genes and genome of Neurospora, setting the stage for research that will follow completion of the genome sequence.This book, which is fully documented and abundantly illustrated, will be an indispensable tool in any laboratory that uses fungi for research in molecular genetics, classical genetics, developmental genetics, or cell biology.

  • Mims' Pathogenesis of Infectious Disease

    • 5 Edición
    • Anthony A. Nash + 2 más
    • Inglés
    Mims' Pathogenesis of Infectious Disease is the landmark book in the field of infectious disease. The new, revised edition of this work provides a comprehensive, up-to-date description of the mechanisms of microbial infection and the pathogenesis of infectious disease. Presented in a clear, accessible style, it deals in an integrated manner with the spectrum of microorganisms, describing the factors common to all infectious diseases. Molecular biology, pathology, and immunology are brought together to explain the mechanisms for spread, immune response, and recovery.

  • HIV I: Molecular Biology and Pathogenesis: Clinical Applications

    • 1 Edición
    • Volumen 49
    • Inglés
    The cumulative death toll from AIDS has reached 16.3 million individuals, and more than 33 million persons are currently living with HIV-1. Although it is one of the most-widely studied viruses, many mysteries remain about this pathogen. In this comprehensive two-volume set, HIV-1: Molecular Biology and Pathogenesis, leading investigators in HIV research present a timely picture of the molecular mechanisms which guide HIV-1 expression and replication and provide the most current clinical strategies for combating this virus. Twenty-six teams of experts unravel structure-function interactions of HIV-1 with host cells and the resulting pathological consequences, review strategies fo treatment, and describe ongoing progress in developing animal models and prophylactic vaccines.The two volumes, covering viral mechanisms and clinical applications, respectively, are written by an international collection of AIDS expers from North America, Europe, Australia, and Asia.

  • The Quinolones

    • 3 Edición
    • Vincent T. Andriole
    • Inglés
    Quinolones constitute a large class of synthetic antimicrobial agents that are highly effective in the treatment of many types of infectious diseases, particularly those caused by bacteria. New quinolones are continually being developed as bacterial species develop resistance to existing quinolones. This book presents the most current information available in our continual struggle to conquer disease. Over time, bacteria become resistant to medicines that are used to combat them. Because of this, the medical world is always in search of new and improved ways to battle these disease-causing bacteria. Quinolones are at the forefront of this research. Edited by one of the world's foremost authorities on the subject, the third edition of this highly successful title will serve as a valuable tool for primary care physicians and researchers interested in a comprehensive, up-to-date reference on the chemistry, mechanisms of action, development of resistance, and clinical efficacy of both currently available and newer quinolone compounds under investigation. This is the eagerly anticipated fully revised edition of the standard reference in the field.

  • Hepatitis C

    • 1 Edición
    • Volumen 2
    • Inglés
    The anticipated encore volume of the Biomedical Research Reports Series, Hepatitis C is the first book that offers comprehensive and up-to-date coverage of this "silent epidemic." The subject matter ranges from basic science to clinical medicine, with contributions from more than 30 international experts in the field. This important new book details the hepatitis C virus and the disease that it causes, including its prevalence, means of spread, symptoms, complications, natural history, prevention, and therapy.The editors, T. Jake Liang, M.D., and Jay H. Hoofnagle, M.D., are both hepatologists and clinical and laboratory researchers who are well known leaders in the hepatitis field. Their team of authors provide the latest information on key issues such as the role of hepatitis C in liver cancer and evolving therapy for hepatitis C, including special subgroups of patients such as children, patients with renal failure, patients undergoing liver transplantation, and patients with HIV coinfection. The book also addresses future directions in antiviral therapy of hepatitis C and the real challenges of developing a vaccine. Hepatitis C is the integrated reference book for all researchers, clinicians, and students dealing with this troubling virus.

  • HIV: Molecular Biology and Pathogenesis: Viral Mechanisms

    • 1 Edición
    • Volumen 48
    • Inglés
    The cumulative death toll from AIDS has reached 16.3 million individuals, and more than 33 million persons are currently living with HIV-1. Although it is one of the most-widely studied viruses, many mysteries remain about this pathogen. In this comprehensive two-volume set, HIV-1: Molecular Biology and Pathogenesis, leading investigators in HIV research present a timely picture of the molecular mechanisms which guide HIV-1 expression and replication and provide the most current clinical strategies for combating this virus. Twenty-six teams of experts unravel structure-function interactions of HIV-1 with host cells and the resulting pathological consequences, review strategies fo treatment, and describe ongoing progress in developing animal models and prophylactic vaccines.The two volumes, covering viral mechanisms and clinical applications, respectively, are written by an international collection of AIDS expers from North America, Europe, Australia, and Asia.

  • Advances in Immunology

    • 1 Edición
    • Volumen 75
    • Inglés
    Advances in Immunology presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for future research.

  • Wine Science

    Principles, Practice, Perception
    • 2 Edición
    • Ronald S. Jackson
    • Inglés
    The second edition of Wine Science: Principles, Practice, Perception updates the reader with current processes and methods of wine science, including an analysis of the advantages and disadvantages of various new grape cultivar clones, wine yeast strains, and malolactic bacteria. It also addresses current research in wine consumption as related to health. The many added beautiful color photographs, graphs, and charts help to make the sophisticated techniques described easily understandable. This book is an essential part of a any library.

  • Viral Ecology

    • 1 Edición
    • Christon J. Hurst
    • Inglés
    Viral Ecology defines and explains the ecology of viruses by examining their interactions with their hosting species, including the types of transmission cycles that have evolved, encompassing principal and alternate hosts, vehicles, and vectors. It examines virology from an organismal biology approach, focusing on the concept that viral infections represent areas of overlap in the ecology of viruses, their hosts, and their vectors.

  • Pathology and Pathogenesis of Human Viral Disease

    • 1 Edición
    • John E. Craighead
    • Inglés
    Pathology and Pathogenesis of Human Viral Disease is a comprehensive reference that examines virus-induced clinical disease of humans in the context of the responsible virus and its epidemiology. Encompassing everything from cold and flu viruses to sexually transmitted diseases, this important resource describes the cellular and tissue pathological changes attributable to infection in the context of the pathogenic mechanisms involved. The author provides a comprehensive review of the older and contemporary literature, considering both the common and much rarer complications of infection. Pathology and Pathogenesis of Human Viral Disease is written from the unique perspective of the clinical pathologist. It will help clinicians and pathologists gain a better understanding of changes that occur in viral infected cells, tissues, and organs. It will also serve as a pathology source book for virologists, internists, and pediatricians.

  • Phagocytosis: Microbial Invasion

    • 1 Edición
    • Volumen 6
    • S. Gordon
    • Inglés
    The present volume focuses on microbial invasion strategies of pathogen uptake. An accompanying volume (Vol. 5) in the series presents the phagocytic process from the viewpiont of the host cell. This field of study is growing rapidly after a somewhat slow start over recent decades. This collection of invited chapters attempts to reflect current research and brings together cell biologists, microbiologists, and immunologists wiht disthemes, hopefully like a symphony rather than a boring catalogue. It will be evident that editorial bias favors intracellular parasitism and medically important organisms. The neutrophil is far more than a supporting player to the macrophage and some attempt is made to remind the reader of some of its unique skills. To retain a manageable size, the emphasis is on relatively early events such as mutual recognition, cell entry, and response, rather than on longterm changes in gene expression by either host cell or pahtogen. Viruses are excluded not because of lack of importance but because of somewhat different research approaches, although it is becoming increasingly clear that large viruses (e.g. Vaccinia) and Listeria monocytogenes, share common strategies in invasion and intercellular spread.

  • Encyclopedia of Microbiology, Four-Volume Set

    • 2 Edición
    • Joshua Lederberg + 9 más
    • Inglés
    The First Edition of the Encyclopedia of Microbiology was hailed by leading scientists and researchers around the world as "excellent," "outstanding," and "impressive." This Second Edition will serve as an up-to-date version of this reference which has been useful to academic, industrial, and personal libraries for years. The Encyclopedia of Microbiology, Second Edition both challenges and stimulates the reader, and illustrates the importance of microbiology, a field that cannot be over emphasized in this booming biotechnology age.

  • Sexually Transmitted Diseases

    Vaccines, Prevention, and Control
    • 1 Edición
    • Lawrence R. Stanberry + 1 más
    • Inglés
    There are 12 million new cases of sexually transmitted diseases every year.This growing world-wide problem has captured the concern of medical professionals, behavioural scientists, and public health officials.Sexually Transmitted Diseases: Vaccines, Prevention and Control provides a comprehensive assessment of the global epidemiology of sexually transmitted diseases plus current data on various strategies for controlling the epidemic, with particular focus on vaccines. The editors and authors represent the leading authorities in the field and provide international and multi-disciplinary expertise.This book is essential reading for all researchers and clinicians working in infectious diseases, virology, microbiology, immunology and vaccine development. This work will also be of key interest to medical students, physicians and workers in pharmaceutical and biotechnology companies and public and world health organisations.

  • Advances in Immunology

    • 1 Edición
    • Volumen 74
    • Inglés
    Advances in Immunology presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for future research.

  • Advances in Antiviral Drug Design

    • 1 Edición
    • Volumen 3
    • E. De Clercq
    • Inglés
    Volume 3 of Advances in Antiviral Drug Design is keeping up with the recent progress made in the field of antiviral drug research and highlights five specific directions that have opened new avenues for the treatment of virus infections. First, the use of lamivudine (3TC) for the treatment of HIV infections, and its more recent introduction for the treatment of hepatitis B virus (HBV) infections, has heralded the transition of D- to L-nucleosides in the antiviral nucleoside drug design, and it is likely that the future will provide more nucleosides of the L-configuration, such as (-)FFC (emtricitabine) and L-FMAU, as will be described by J.-C.G. Graciet and R.F. Shinazi. Second, the acyclic purine nucleoside phosphonates, i.e. PMEA (adefovir and PMPA (tenofovir), offer great potential as both anti-HIV and anti-HBV agents, and both compounds have been the subject of advanced clinical trials in their oral produrg form (adefovir dipivoxil and tenofovir disoproxyl), as mentioned by M.N. Arimilli, J.P. Dougherty, K.C. Cundy, and N. Bischofberger.Third, with the advent of nevirapine, delavirdine, and efavirenz, the NNRTIs have definitely come of age. Emivirine (MKC-442), a derivative of the original HEPT analog that was described in 1989 has now proceeded through pivotal clinical studies, and how this class of compounds evolved is presented in the account of H. Tanaka and his colleagues. Fourth, at the end of 1999, anticipating on the next winter influenza offensive, we should have at end two compounds that specifically inhibit influenza A and B virus infections: zanamivir (by the intranasal route) and oseltamivir (by the oral route). Both compounds have proved effective in the prophylaxis and treatment of influenza A and B virus infections and act through the same mechanism; that is by blocking the viral neuraminidase (or sialidase), a key enzyme that allows the virus to spread from one cell to another (within the respiratory mucosal tract). The design of these sialidase inhibitors will be presented by M. von Itzstein and J.C. Dyason.Fifth, the discovery (in 1996) of the chemokine receptors CXCR4 and CCR5 as essential coreceptors (in addition to the CD4 receptor) for HIV entry into the cells, has boosted an enormous interest in potential antagonists of these receptors. The bicyclams represent the first low-molecular-weight compounds targeted at CXCR4, the coreceptor used by the more pathogenic, T-lymphotropic, HIV strains, to enter the cells. They will be addressed by G.J. Bridger and R.T. Skerlj.The five topics covered in this third volume of Advances in Antiviral Drug Design are in the front line of the present endeavors towards the chemotherapy of virus infections. They pertain to the combat against three of the most important virus infections of current times: HIV, HBV, and influenza virus.

  • Women and Health

    • 1 Edición
    • Marlene B. Goldman + 1 más
    • Inglés
    Women and Health is a comprehensive reference which addresses health issues affecting women of all ages--adolescence through maturity. It goes far beyond other books on this topic which concentrate only on reproductive health, and has a truly international perspective. It covers key issues ranging from osteoporosis to breast cancer and other cancers, domestic violence, sexually transmitted diseases, occupational hazards, eating disorders, heart disease and other chronic illnesses, substance abuse, and societal and behavioral influences on health. Women and Health covers not only those conditions that are unique to or occur more frequently in women, but also those that present differently or are treated differently in women.

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