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Elsevier

Libros en Química

  • Profiles of Drug Substances, Excipients and Related Methodology

    Critical Compilation of pKa Values for Pharmaceutical Substances
    • 1 Edición
    • Volumen 33
    • Harry G. Brittain
    • Inglés
    Whilst following in the footsteps of previous volumes by presenting comprehensive reviews of drug substances and additional materials, this title also heralds a significant expansion of the scope of the series. Traditional contributions will now also be augmented by publication of critical review chapters that summarize information related to the characterization of drug substances and excipients. This change is required to better meet the needs of the pharmaceutical communtiy and to allow the development of a timely vehicle for publishing review materials on this topic. The scope of the Profiles series will encompass review articles and database compilations that fall within one of the following six broad categories: Physical profiles of drug substances and excipients; Analytical profiles of drug substances and excipients; Drug metabolism and pharmacokinetic profiles of drug substances and excipients; Methodology related to the characterization of drug substances and excipients; Methods of chemical synthesis; and Reviews of the uses and applications for individual drug substances, classes of drug substances, or excipients.

  • Lipidomics and Bioactive Lipids: Specialized Analytical Methods and Lipids in Disease

    • 1 Edición
    • Volumen 433
    • Inglés
    This volume in the well-established Methods in Enzymology series features methods for the study of lipids using mass spectrometry techniques. Articles in this volume cover topics such as Liquid chromatography mass spectrometry for quantifying plasma lysophospholipids: potential biomarkers for cancer diagnosis; Measurement of eicosanoids in cancer tissues; Noninvasive Assessment of the Role of Cyclooxygenases in Cardiovascular HealthA Detailed HPLC/MS/MS Method; Lipidomics in Diabetes and the Metabolic Syndrome; LC-MS-MS Analysis of Neutral Eicosanoids; Quantification Of F2-Isoprostanes In Biological Fluids And Tissues As A Measure Of Oxidant Stress; Measurement of Products of Docosahexaenoic Acid Peroxidation, Neuroprostanes, and Neurofurans; Enantiomeric separation of hydroxy and hydroperoxy eicosanoids by chiral column chromatography; Targeted Chiral Lipidomics Analysis by Liquid Chromatography Electron Capture Atmospheric Pressure Chemical Ionization Mass Spectrometry (LC-ECAPCI/MS); Shotgun Lipidomics by Tandem Mass Spectrometry under Data-Dependent Acquisition Control; Identification of Intact Lipid Peroxides by Ag+ Coordination Ionspray Mass Spectrometry (CIS-MS); Quantification of Cardiolipin by Liquid Chromatography Electrospray Ionization Mass Spectrometry.

  • Handbook of Thermal Analysis and Calorimetry

    Recent Advances, Techniques and Applications
    • 1 Edición
    • Volumen 5
    • Inglés
    This is Volume 5 of a Handbook that has been well-received by the thermal analysis and calorimetry community. All chapters in all five volumes are written by international experts in the subject. The fifth volume covers recent advances in techniques and applications that complement the earlier volumes. The chapters refer wherever possible to earlier volumes, but each is complete in itself. The latest recommendations on Nomenclature are also included. Amongst the important new techniques that are covered are micro-thermal analysis, pulsed thermal analysis, fast-scanning calorimetery and the use of quartz-crystal microbalances. There are detailed reviews of heating - stage spectroscopy, the range of electrical techniques available, applications in rheology, catalysis and the study of nanoparticles. The development and application of isoconversional methods of kinetic analysis are described and there are comprehensive chapters on the many facets of thermochemistry and of measuring thermophysical properties. Applications to inorganic and coordination chemistry are reviewed, as are the latest applications in medical and dental sciences, including the importance of polymorphism. The volume concludes with a review of the use and importance of thermal analysis and calorimetry in quality control.

  • Forensic Science

    • 2 Edición
    • Volumen 6
    • Inglés
    Forensic Science, Second Edition presents the applications of separation methods, manly chromatography, in forensic practice. The first part, devoted to forensic toxicology, contains reviews on forensic relevant groups of compounds, like: Opiate agonists, cocaine, amphetamines, hallucinogens, cannabinoids, sedatives and hypnotics, antidepressive and antipsychotic drugs, analgesics, antidiabetics, muscle relaxants, and mushroom toxins.In these parts, the preliminary immunochemical tests were also included, together with separation methods. Screening procedures used in forensic toxicology were presented in separate chapters on forensic screening with GC, GC-MS, HPLC, LC-MS, CE, and LC-ICP-MS. In the part on actual and emerging problems of forensic toxicology, following chapters were included: Analytical markers of alcohol abuse, toxicological aspects of herbal remedies, drugs and driving, analysis in alternative matrices, doping analysis, pharmacogenomics in forensic toxicology, and quality assurance. The second part presents application of separation methods in forensic chemistry, and comprises chapters on: Explosives, chemical warfare agents, arson analysis, and writing media. Third part on forensic identification contains chapter on forensic genetics.All chapters are written up-to-date and present specific information up to 2006. The authors of each chapter are known not only from their scientific activity, but are also reputed experts, proven in everyday forensic casework.

  • Medical Applications of Mass Spectrometry

    • 1 Edición
    • Karoly Vekey + 2 más
    • Inglés
    Mass spectrometry is fast becoming an indispensable field for medical professionals. The mass spectrometric analysis of metabolites and proteins promises to revolutionize medical research and clinical diagnostics. As this technology rapidly enters the medical field, practicing professionals and students need to prepare to take full advantage of its capabilities. Medical Applications of Mass Spectrometry addresses the key issues in the medical applications of mass spectrometry at the level appropriate for the intended readership. It will go a long way to help the utilization of mass spectrometry in medicine.The book comprises five parts. A general overview is followed by a description of the basic sampling and separation methods in analytical chemistry. In the second part a solid foundation in mass spectrometry and modern techniques of data analysis is presented. The third part explains how mass spectrometry is used in exploring various classes of biomolecules, including proteins and lipids. In the fourth section mass spectrometry is introduced as a diagnostic tool in clinical treatment, infectious pathogen research, neonatal diagnostics, cancer, brain and allergy research, as well as in various fields of medicine: cardiology, pulmonology, neurology, psychiatric diseases, hemato-oncology, urologic diseases, gastrointestinal diseases, gynecology and pediatrics. The fifth part covers emerging applications in biomarker discovery and in mass spectrometric imaging.

  • Spectroscopy and Modeling of Biomolecular Building Blocks

    • 1 Edición
    • Jean-Pierre Schermann
    • Inglés
    Spectroscopy and Modeling of Biomolecular Building Blocks presents an overview of recent advances in the intertwining of the following research fields: photon and electron spectroscopy, quantum chemistry, modelling and mass-spectrometry. The coupling of these disciplines offers a new point of view to the understanding of isolated elementary building blocks of biomolecules and their assemblies. It allows the unambiguous separation between intrinsic properties of biomolecular systems and those induced by the presence of their environment. The first chapters provide background in modelling (I), frequency-resolved spectroscopy using microwave, infrared and UV photons, time-resolved spectroscopy in the femtosecond domain and energy-resolved electron spectroscopy (II) and production of gas-phase neutral and ionic biomolecular species, mass-spectrometry, ion mobility and BIRD techniques (III). Chapter IV is devoted to case studies of gas-phase experimental investigations coupled to quantum or classical calculations. The topics are structural studies of nucleobases and oligonucleotides, peptides and proteins, sugars; neuromolecules; non-covalent complexes; chiral systems, interactions of low-energy electrons with biomolecules in the radiation chemistry context and very large gas-phase biomolecular systems. The fifth chapter concerns the link between gas-phase and liquid-phase. Different treatments of solvation are illustrated through examples pointing out the influence of progressive addition of water molecules upon properties of nucleobases, peptides, sugars and neuromolecules.

  • Advances in Organometallic Chemistry

    • 1 Edición
    • Volumen 55
    • Robert C. West + 2 más
    • Inglés
    Almost all branches of chemistry and material science now interface with organometallic chemistry - the study of compounds containing carbon-metal bonds. This widely acclaimed serial contains authoritative reviews that address all aspects of organometallic chemistry, a field which has expanded enormously since the publication of Volume 1 in 1964.

  • Annual Reports on NMR Spectroscopy

    • 1 Edición
    • Volumen 62
    • Graham A. Webb
    • Inglés
    Nuclear magnetic resonance (NMR) is an analytical tool used by chemists and physicists to study the structure and dynamics of molecules. In recent years, no other technique has grown to such importance as NMR spectroscopy. It is used in all branches of science when precise structural determination is required and when the nature of interactions and reactions in solution is being studied. Annual Reports on NMR Spectroscopy has established itself as a premier means for the specialist and nonspecialist alike to become familiar with new techniques and applications of NMR spectroscopy.

  • Solid-Liquid Two Phase Flow

    • 1 Edición
    • Sümer M. Peker + 1 más
    • Inglés
    This book is an undertaking of a pioneering work of uniting three vast fields of interfacial phenomena, rheology and fluid mechanics within the framework of solid-liquid two phase flow. No wonder, much finer books will be written in the future as the visionary aims of many nations in combining molecular chemistry, biology, transport and interfacial phenomena for the fundamental understanding of processes and capabilities of new materials will be achieved. Solid-liquid systems where solid particles with a wide range of physical properties, sizes ranging from nano- to macro- scale and concentrations varying from very dilute to highly concentrated, are suspended in liquids of different rheological behavior flowing in various regimes are taken up in this book. Interactions among solid particles in molecular scale are extended to aggregations in the macro scale and related to settling, flow and rheological behavior of the suspensions in a coherent, sequential manner. The classical concept of solid particles is extended to include nanoparticles, colloids, microorganisms and cellular materials. The flow of these systems is investigated under pressure, electrical, magnetic and chemical driving forces in channels ranging from macro-scale pipes to micro channels. Complementary separation and mixing processes are also taken under consideration with micro- and macro-scale counterparts.

  • Advances in Carbohydrate Chemistry and Biochemistry

    • 1 Edición
    • Volumen 61
    • Inglés
    Since its inception in 1945, this serial has provided critical and integrating articles written by research specialists that integrate industrial, analytical, and technological aspects of biochemistry, organic chemistry, and instrumentation methodology in the study of carbohydrates. The articles provide a definitive interpretation of the current status and future trends in carbohydrate chemistry and biochemistry.

  • Laser-Induced Breakdown Spectroscopy

    • 1 Edición
    • Jagdish P. Singh + 1 más
    • Inglés
    Laser induced breakdown spectroscopy (LIBS) is basically an emission spectroscopy technique where atoms and ions are primarily formed in their excited states as a result of interaction between a tightly focused laser beam and the material sample. The interaction between matter and high-density photons generates a plasma plume, which evolves with time and may eventually acquire thermodynamic equilibrium. One of the important features of this technique is that it does not require any sample preparation, unlike conventional spectroscopic analytical techniques. Samples in the form of solids, liquids, gels, gases, plasmas and biological materials (like teeth, leaf or blood) can be studied with almost equal ease. LIBS has rapidly developed into a major analytical technology with the capability of detecting all chemical elements in a sample, of real- time response, and of close-contact or stand-off analysis of targets. The present book has been written by active specialists in this field, it includes the basic principles, the latest developments in instrumentation and the applications of LIBS . It will be useful to analytical chemists and spectroscopists as an important source of information and also to graduate students and researchers engaged in the fields of combustion, environmental science, and planetary and space exploration.

  • Solution Thermodynamics and its Application to Aqueous Solutions

    A Differential Approach
    • 1 Edición
    • Yoshikata Koga
    • Inglés
    As the title suggests, we introduce a novel differential approach to solution thermodynamics and use it for the study of aqueous solutions. We evaluate the quantities of higher order derivative than the normal thermodynamic functions. We allow these higher derivative data speak for themselves without resorting to any model system. We thus elucidate the molecular processes in solution, (referred to in this book “mixing scheme”), to the depth equal to, if not deeper, than that gained by spectroscopic and other methods. We show that there are three composition regions in aqueous solutions of non-electrolytes, each of which has a qualitatively distinct mixing scheme. The boundary between the adjacent regions is associated with an anomaly in the third derivatives of G. The loci of the anomalies in the temperature-composit... field form the line sometimes referred as “Koga line”. We then take advantage of the anomaly of a third derivative quantity of 1-propanol in the ternary aqueous solution, 1-propanol – sample species – H2O. We use its induced change as a probe of the effect of a sample species on H2O. In this way, we clarified what a hydrophobe, or a hydrophile, and in turn, an amphiphile, does to H2O. We also apply the same methodology to ions that have been ranked by the Hofmeister series. We show that the kosmotropes (salting out, or stabilizing agents) are either hydrophobes or hydration centres, and that chaotropes (salting in, or destablizing agents) are hydrophiles.

  • Annual Reports in Computational Chemistry

    • 1 Edición
    • Volumen 3
    • David Spellmeyer + 1 más
    • Inglés
    Annual Reports in Computational Chemistry is a new periodical providing timely and critical reviews of important topics in computational chemistry as applied to all chemical disciplines. Topics covered include quantum chemistry, molecular mechanics, force fields, chemical education, and applications in academic and industrial settings. Each volume is organized into (thematic) sections with contributions written by experts. Focusing on the most recent literature and advances in the field, each article covers a specific topic of importance to computational chemists. Annual Reports in Computational Chemistry is a 'must' for researchers and students wishing to stay up-to-date on current developments in computational chemistry.In Volume 3, topics covered include Simulation Methodologies (Carlos Simmerling), Biological and Biophysical Applications (Heather Carlson), Chemical Education (Theresa Zielinski), Materials and Polymers (Jeffry Madura), Quantum Chemistry (T. Daniel Crawford), and Emerging Technologies (Wendy Cornell). With this volume we extend the practice of cumulative indexing of both the current and past editions in order to provide easy identification of past reports.

  • Magnetic Cell Separation

    • 1 Edición
    • Volumen 32
    • Inglés
    Cell separation is at the core of current methods in experimental biology and medicine. Its importance is illustrated by the large number of physical and biochemical principles that have been evaluated for application to cell separation. The development of cell separation methods is driven by the needs of biological and medical research, and the ever-increasing demands for sensitivity, selectivity, yield, timeliness and economy of the process. The interdisciplinary nature of research in this area and the volume of information available in research publications and conferences necessitates a basic description of the fundamental processes involved in magnetic cell separation that may help the user in navigating this wealth of information available online and in scientific publications. This book will appeal to researchers in many areas utilizing this technique, including those working in cell biology, clinical research, inorganic chemistry, biochemistry, chemical engineering, materials science, physics and electrical engineering.

  • Progress in Heterocyclic Chemistry

    • 1 Edición
    • Volumen 19
    • Gordon Gribble + 1 más
    • Inglés
    This is the 19th annual volume of Progress in Heterocyclic Chemistry, which covers the literature published during 2006. As with previous volumes in the series, Volume 19 will enable the reader to keep abreast of developments in heterocyclic chemistry in an effortless way.

  • Introduction to Non-equilibrium Physical Chemistry

    • 1 Edición
    • R. P. Rastogi
    • Inglés
    Introduction to Non-equilibrium Physical Chemistry presents a critical and comprehensive account of Non-equilibrium Physical Chemistry from theoretical and experimental angle. It covers a wide spectrum of non-equilibrium phenomena from steady state close to equilibrium to non-linear region involving transition to bistability, temporal oscillations, spatio-temporal oscillations and finally to far from equilibrium phenomena such as complex pattern formation, dynamic instability at interfaces, Chaos and complex growth phenomena (fractals) in Physico-chemical systems. Part I of the book deals with theory and experimental studies concerning transport phenomena in membranes (Thermo-osmosis,Elec... ) and in continuous systems (Thermal diffusion,Soret effect) close to equilibrium Experimental tests provide insight into the domain of validity of Non-equilibrium Thermodynamics ,which is the major theoretical tool for this region. Later developments in Extended Irreversible Thermodynamics and Non-equilibrium Molecular dynamics have been discussed in the Appendix. Part II deals with non-linear steady states and bifurcation to multistability, temporal and spatio- temporal oscillations (Chemical waves). Similarly Part II deals with more complex phenomena such as Chaos and fractal growth occurring in very far from equilibrium region. Newer mathematical techniques for investigating such phenomena along with available experimental studies. Part IV deals with analogous non-equilibrium phenomena occurring in the real systems (Socio-political, Finance and Living systems etc.) for which physico-chemical systems discussed in earlier chapters provide a useful model for development of theories based on non-linear science and science of complexity.

  • Chemical Bonding at Surfaces and Interfaces

    • 1 Edición
    • Anders Nilsson + 2 más
    • Inglés
    Molecular surface science has made enormous progress in the past 30 years. The development can be characterized by a revolution in fundamental knowledge obtained from simple model systems and by an explosion in the number of experimental techniques. The last 10 years has seen an equally rapid development of quantum mechanical modeling of surface processes using Density Functional Theory (DFT). Chemical Bonding at Surfaces and Interfaces focuses on phenomena and concepts rather than on experimental or theoretical techniques. The aim is to provide the common basis for describing the interaction of atoms and molecules with surfaces and this to be used very broadly in science and technology. The book begins with an overview of structural information on surface adsorbates and discusses the structure of a number of important chemisorption systems. Chapter 2 describes in detail the chemical bond between atoms or molecules and a metal surface in the observed surface structures. A detailed description of experimental information on the dynamics of bond-formation and bond-breaking at surfaces make up Chapter 3. Followed by an in-depth analysis of aspects of heterogeneous catalysis based on the d-band model. In Chapter 5 adsorption and chemistry on the enormously important Si and Ge semiconductor surfaces are covered. In the remaining two Chapters the book moves on from solid-gas interfaces and looks at solid-liquid interface processes. In the final chapter an overview is given of the environmentally important chemical processes occurring on mineral and oxide surfaces in contact with water and electrolytes.

  • Electrochemical Sensor Analysis

    • 1 Edición
    • Volumen 49
    • Salvador Alegret + 1 más
    • Inglés
    Electrochemical Sensor Analysis (ECSA) presents the recent advances in electrochemical (bio)sensors and their practical applications in real clinical, environment, food and industry related samples, as well as in the safety and security arena. In a single source, it covers the entire field of electrochemical (bio)sensor designs and characterizations. The 38 chapters are grouped in seven sections: 1) Potentiometric sensors, 2) Voltammetric sensors, 3) Electrochemical gas sensors 4) Enzyme-based sensors 5) Affinity biosensors 6) Thick and thin film biosensors and 7) Novel trends. Written by experts working in the diverse technological and scientific fields related to electrochemical sensors, each section provides an overview of a specific class of electrochemical sensors and their applications. This interdisciplinary text will be useful for researchers and professionals alike.

  • Modeling of Chemical Reactions

    • 1 Edición
    • Volumen 42
    • R.W. Carr
    • Inglés
    Modeling of Chemical Reactions covers detailed chemical kinetics models for chemical reactions. Including a comprehensive treatment of pressure dependent reactions, which are frequently not incorporated into detailed chemical kinetic models, and the use of modern computational quantum chemistry, which has recently become an extraordinarily useful component of the reaction kinetics toolkit. It is intended both for those who need to model complex chemical reaction processes but have little background in the area, and those who are already have experience and would benefit from having a wide range of useful material gathered in one volume. The range of subject matter is wider than that found in many previous treatments of this subject. The technical level of the material is also quite wide, so that non-experts can gain a grasp of fundamentals, and experts also can find the book useful.

  • Analysis, Removal, Effects and Risk of Pharmaceuticals in the Water Cycle

    Occurrence and Transformation in the Environment
    • 1 Edición
    • Volumen 62
    • Inglés
    Pharmaceutically active substances are a class of new, so-called "emerging" contaminants that have raised great concern in recent years. Human and veterinary drugs are constantly being introduced into the environment, mainly as a result of the manufacturing process. Over time, this level of chemical input may lead to long-term concentrations and promote continual, but unnoticed adverse effects on aquatic and terrestrial organisms. Analysis, Fate and Removal of Pharmaceuticals in the Water Cycle discusses state-of-the-art analytical methods for trace determination of pharmaceuticals in environmental samples while reviewing the fate and occurrence of pharmaceuticals in the water cycle (elimination in wastewater and drinking water treatment). Focus is given to the newest developments in the treatment technologies, such as membrane bioreactors and advance oxidation processes.

  • Nonequilibrium Thermodynamics

    Transport and Rate Processes in Physical, Chemical and Biological Systems
    • 2 Edición
    • Yasar Demirel
    • Inglés
    Natural phenomena consist of simultaneously occurring transport processes and chemical reactions. These processes may interact with each other and lead to instabilities, fluctuations, and evolutionary systems. This book explores the unifying role of thermodynamics in natural phenomena. Nonequilibrium Thermodynamics, Second Edition analyzes the transport processes of energy, mass, and momentum transfer processes, as well as chemical reactions. It considers various processes occurring simultaneously, and provides students with more realistic analysis and modeling by accounting possible interactions between them. This second edition updates and expands on the first edition by focusing on the balance equations of mass, momentum, energy, and entropy together with the Gibbs equation for coupled processes of physical, chemical, and biological systems. Every chapter contains examples and practical problems to be solved. This book will be effective in senior and graduate education in chemical, mechanical, systems, biomedical, tissue, biological, and biological systems engineering, as well as physical, biophysical, biological, chemical, and biochemical sciences.

  • Principles of Chemical Kinetics

    • 2 Edición
    • James E. House
    • Inglés
    James House's revised Principles of Chemical Kinetics provides a clear and logical description of chemical kinetics in a manner unlike any other book of its kind. Clearly written with detailed derivations, the text allows students to move rapidly from theoretical concepts of rates of reaction to concrete applications. Unlike other texts, House presents a balanced treatment of kinetic reactions in gas, solution, and solid states. The entire text has been revised and includes many new sections and an additional chapter on applications of kinetics. The topics covered include quantitative relationships between molecular structure and chemical activity, organic/inorganic chemistry, biochemical kinetics, surface kinetics and reaction mechanisms. Chapters also include new problems, with answers to selected questions, to test the reader's understanding of each area. A solutions manual with answers to all questions is available for instructors. A useful text for both students and interested readers alike, Dr. House has once again written a comprehensive text simply explaining an otherwise complicated subject.

  • Chemometrics in Spectroscopy

    • 1 Edición
    • Howard Mark + 1 más
    • Inglés
    Chemometrics in Spectroscopy builds upon the statistical information covered in other books written by these leading authors in the field by providing a broader range of mathematics and progressing into the fundamentals of multivariate and experimental data analysis. Subjects covered in this work include: matrix algebra, analytic geometry, experimental design, calibration regression, linearity, design of collaborative laboratory studies, comparing analytical methods, noise analysis, use of derivatives, analytical accuracy, analysis of variance, and much more are all part of this chemometrics compendium. Developed in the form of a tutorial offering a basic hands-on approach to chemometric and statistical analysis for analytical scientists, experimentalists, and spectroscopists. Without using complicated mathematics, Chemometrics in Spectroscopy demonstrates the basic principles underlying the use of common experimental, chemometric, and statistical tools. Emphasis has been given to problem-solving applications and the proper use and interpretation of data used for scientific research.

  • An Introduction to Aspects of Thermodynamics and Kinetics Relevant to Materials Science

    • 3 Edición
    • Eugene Machlin
    • Inglés
    This book is based on a set of notes developed over many years for an introductory course taught to seniors and entering graduate students in materials science. An Introduction to Aspects of Thermodynamics and Kinetics Relevant to Materials Science is about the application of thermodynamics and kinetics to solve problems within Materials Science. Emphasis is to provide a physical understanding of the phenomenon under discussion, with the mathematics presented as a guide. The problems are used to provide practice in quantitative application of principles, and also to give examples of applications of the general subject matter to problems having current interest and to emphasize the important physical concepts. End of chapter problems are included, as are references, and bibliography to reinforce the text. This book provides students with the theory and mathematics to understand the important physical understanding of phenomena.

  • Lectins: Analytical Technologies

    • 1 Edición
    • Carol L. Nilsson
    • Inglés
    Lectins: Analytical Technologies covers both analytical and biological aspects of lectins (functional carbohydrate (complex sugar) recognition proteins) and provides researchers in the field with a resource containing background information and 'look-up' tables detailing lectin specificity and structures. Also included are methods and practical tips for designing new lectins from existing non-lectin proteins, automated approaches to lectin proteomics and high resolution mass spectrometry techniques. This book will be of interest to both novice and advanced researchers in biomedical, analytical and pharmaceutical fields who are involved in the study of lectin structures or who utilize lectins as analytical tools. The study of lectins and their employment in analytical settings spans a range of fields including: * Crystallography and lectin structure databases* Carbohydrate microarrays for lectin characterization and glycotope identification* Proteomic approaches to the functional identification of bacterial adhesins* Generation of lectins from enzymes* Probing cell-surface lectins with neoglycoconjugates

  • Radioactivity: Introduction and History

    • 1 Edición
    • Michael F. L'Annunziata
    • Inglés
    Radioactivity: Introduction and History provides an introduction to radioactivity from natural and artificial sources on earth and radiation of cosmic origins. This book answers many questions for the student, teacher, and practitioner as to the origins, properties, detection and measurement, and applications of radioactivity. Written at a level that most students and teachers can appreciate, it includes many calculations that students and teachers may use in class work. Radioactivity: Introduction and History also serves as a refresher for experienced practitioners who use radioactive sources in his or her field of work. Also included are historical accounts of the lives and major achievements of many famous pioneers and Nobel Laureates who have contributed to our knowledge of the science of radioactivity.

  • Eisler's Encyclopedia of Environmentally Hazardous Priority Chemicals

    • 1 Edición
    • Ronald Eisler
    • Inglés
    Thousands of inorganic and organic chemicals and their metabolites enter the biosphere daily as a direct result of human activities. Many of these chemicals have serious consequences on sensitive species of natural resources, crops, livestock, and public health. The most hazardous of these were identified by a panel of environmental specialists from the U.S. Fish and Wildlife Service; these chemicals are the focus of this encyclopedia.For each priority group of chemicals, information is presented on sources, uses, physical and chemical properties, tissue concentrations in field collections and their significance, lethal and sublethal effects under controlled conditions. This includes effects on survival, growth, reproduction, metabolism, carcinogenicity, teratogenicity, and mutagenicity - and proposed regulatory criteria for the protection of sensitive natural resources, crops, livestock, and human health. Taxonomic groups of natural resources covered include terrestrial and aquatic plants and invertebrates, fishes, amphibians, reptiles, birds, and mammals.

  • Electronic, Atomic and Molecular Calculations

    Applying the Generator Coordinate Method
    • 1 Edición
    • Milan Trsic + 1 más
    • Inglés
    The Generator Coordinate Method (GCM) is a mathematical tool for the understanding of stable atomic nuclei. Electronic, Atomic and Molecular Calculations is designed to assist scientists applying GCM in the analysis of the electronic structure of atoms and molecules. There have been numerous publications covering nuclear physics and electronic structure of atoms and molecules, but this book is unique in the sense that it specifically addresses the application of GCM for such purposes. Using this book, researchers will be able to understand and calculate the electronic structure in a novel manner.

  • The Chemistry of Pincer Compounds

    • 1 Edición
    • David Morales-Morales + 1 más
    • Inglés
    Pincer complexes are formed by the binding of a chemical structure to a metal atom with at least one carbon-metal bond. Usually the metal atom has three bonds to a chemical backbone, enclosing the atom like a pincer. The resulting structure protects the metal atom and gives it unique properties.The last decade has witnessed the continuous growth in the development of pincer complexes. These species have passed from being curiosity compounds to chemical chameleons able to perform a wide variety of applications. Their unique metal bound structures provide some of the most active catalysts yet known for organic transformations involving the activation of bonds. The Chemistry of Pincer Compounds details use of pincer compounds including homogeneous catalysis, enantioselective organic transformations, the activation of strong bonds, the biological importance of pincer compounds as potential therapeutic or pharmaceutical agents, dendrimeric and supported materials.

  • Advances in Heterocyclic Chemistry

    • 1 Edición
    • Volumen 94
    • Alan R. Katritzky
    • Inglés
    Written by established authorities in the field, the comprehensive reviews combine descriptive chemistry and mechanistic insight and yield an understanding of how the chemistry drives the properties. Volume 94 of Advances in Heterocyclic Chemistry commences with a review of cascade reactions on heterocyclic synthesis. The chapter presents a fascinating array of complex sequences which provide efficient routes to a wide variety of heterocyclic systems. The second chapter is the twelfth in the series on the organic chemistry of heterocyclic ligands in metallic complexes. The present contribution deals with the chemistry of polypyridine ligands in organomanganese and organorhenium complexes. Its current importance can be measured by the fact that, of the nearly 700 references, approximately half date from the last 10 years. Preparation of aminoisoxazoles and their utility in the synthesis of condensed systems are also covered. In the final chapter, isothiazolium salts and their use in synthesis are reviewed. Many condensed S,N-heterocyclic systems are described in this, the first review dedicated to this topic.

  • 17th European Symposium on Computed Aided Process Engineering

    • 1 Edición
    • Volumen 24
    • Valentin Plesu + 1 más
    • Inglés
    The 17th European Symposium on Computed Aided Process Engineering contains papers presented at the 17th European Symposium of Computer Aided Process Engineering (ESCAPE 17) held in Bucharest, Romania, from 27-30 May 2007. The ESCAPE series serves as a forum for scientists and engineers from academia and industry to discuss progress achieved in the area of Computer Aided Process Engineering (CAPE). The main goal was to emphasize the continuity in research of innovative concepts and systematic design methods as well the diversity of applications emerged from the demands of sustainable development. ESCAPE 17 highlights the progresss software technology needed for implementing simulation based tools.The symposium is based on 5 themes and 27 topics, following the main trends in CAPE area: Modelling, Process and Products Design, Optimisation and Optimal Control and Operation, System Biology and Biological Processes, Process Integration and Sustainable Development. Participants from 50 countries attended and invited speakers presented 5 plenary lectures tackling broad subjects and 10 keynote lectures. Satellite events added a plus to the scientific dimension to this symposium.

  • HPLC Method Development for Pharmaceuticals

    • 1 Edición
    • Volumen 8
    • Satinder Ahuja + 1 más
    • Inglés
    High pressure, or high performance, liquid chromatography (HPLC) is the method of choice for checking purity of new drug candidates, monitoring changes during scale up or revision of synthetic procedures, evaluating new formulations, and running control/assurance of the final drug product. HPLC Method Development for Pharmaceuticals provides an extensive overview of modern HPLC method development that addresses these unique concerns. Includes a review and update of the current state of the art and science of HPLC, including theory, modes of HPLC, column chemistry, retention mechanisms, chiral separations, modern instrumentation (including ultrahigh-pressure systems), and sample preparation. Emphasis has been placed on implementation in a pharmaceutical setting and on providing a practical perspective. HPLC Method Development for Pharmaceuticals is intended to be particularly useful for both novice and experienced HPLC method development chemists in the pharmaceutical industry and for managers who are seeking to update their knowledge.

  • Annual Reports on NMR Spectroscopy

    • 1 Edición
    • Volumen 61
    • Graham A. Webb
    • Inglés
    Nuclear magnetic resonance (NMR) is an analytical tool used by chemists and physicists to study the structure and dynamics of molecules. In recent years, no other technique has grown to such importance as NMR spectroscopy. It is used in all branches of science where precise structural determination is required and where the nature of interactions and reactions in solution is being studied. Annual Reports on NMR Spectroscopy has established itself as a premier means for the specialist and nonspecialist alike to become familiar with new techniques and applications of NMR spectroscopy.

  • NMR Quantum Information Processing

    • 1 Edición
    • Ivan Oliveira + 4 más
    • Inglés
    Quantum Computation and Quantum Information (QIP) deals with the identification and use of quantum resources for information processing. This includes three main branches of investigation: quantum algorithm design, quantum simulation andquantum communication, including quantum cryptography. Along the past few years, QIP has become one of the most active area ofresearch in both, theoretical and experimental physics, attracting students and researchers fascinated, not only by the potentialpractical applications of quantum computers, but also by the possibility of studying fundamental physics at the deepest level of quantum phenomena.NMR Quantum Computation and Quantum Information Processing describes the fundamentals of NMR QIP, and the main developments which can lead to a large-scale quantum processor. The text starts with a general chapter onthe interesting topic of the physics of computation. The very first ideas which sparkled the development of QIP came from basic considerations of the physical processes underlying computational actions. In Chapter 2 it is made an introduction to NMR, including the hardware and other experimental aspects of the technique. InChapter 3 we revise the fundamentals of Quantum Computation and Quantum Information. The chapter is very much based on the extraordinary book of Michael A. Nielsen and Isaac L. Chuang, withan upgrade containing some of the latest developments, such as QIP in phase space, and telecloning. Chapter 4 describes how NMRgenerates quantum logic gates from radiofrequency pulses, upon which quantum protocols are built. It also describes the important technique of Quantum State Tomography for both, quadrupole and spin1/2 nuclei. Chapter 5 describes some of the main experiments of quantum algorithm implementation by NMR, quantum simulation and QIP in phase space. The important issue of entanglement in NMR QIPexperiments is discussed in Chapter 6. This has been a particularly exciting topic in the literature. The chapter contains a discussionon the theoretical aspects of NMR entanglement, as well as some of the main experiments where this phenomenon is reported. Finally, Chapter 7 is an attempt to address the future of NMR QIP, based invery recent developments in nanofabrication and single-spin detection experiments. Each chapter is followed by a number of problems and solutions.

  • Significant Pharmaceuticals Reported in US Patents

    • 1 Edición
    • Thomas F. DeRosa
    • Inglés
    Significant Pharmaceuticals Reported in US Patents identifies the next generation of pharmaceuticals reported in US Patents. This "hands-on" title provides explicit laboratory methods for preparing the most recent and effective medications. Each entry documents the biological testing protocols used to evaluate a drug and the significance of the current treatment agent over previous methods. Pharmaceuticals are included in this review only if at least two of the following criteria were met: Effectiveness in treating an illness, Innovative, ease of preparation, synergy with existing Medications. Pharmaceuticals are reported for 27 separate classes of illness, including: AIDS, Alzheimer's Disease, Cardiovascular Disorders, Diabetes, Epilepsy, Hepatitis C, Osteoporosis, Obesity and Sleep Disorders. Significant Pharmaceuticals Reported in US Patents has been designed to be used as both a reference and synthetic guide for pharmaceutical, medicinal and organic chemists and graduate students. Researchers working in other areas will also find the information valuable as in many instances intermediates or the next generation pharmaceutical are readily convertible into other industrial products including: anti-oxidants, chemical additives, herbicides, polymer precursors, water purification agents. Clear structural depictions of reagents and chemical transformations have been supplied to permit the identification of other future applications.

  • Electrochemistry in Light Water Reactors

    Reference Electrodes, Measurement, Corrosion and Tribocorrosion Issues
    • 1 Edición
    • Volumen 49
    • R-W Bosch + 2 más
    • Inglés
    There has long been a need for effective methods of measuring corrosion within light water nuclear reactors. This important volume discusses key issues surrounding the development of high temperature reference electrodes and other electrochemical techniques. The book is divided into three parts with part one reviewing the latest developments in the use of reference electrode technology in both pressurised water and boiling water reactors. Parts two and three cover different types of corrosion and tribocorrosion and ways they can be measured using such techniques as electrochemical impedance spectroscopy. Topics covered across the book include in-pile testing, modelling techniques and the tribocorrosion behaviour of stainless steel under reactor conditions.Electroch... in light water reactors is a valuable reference for all those concerned with corrosion problems in this key technology for the power industry.

  • Advances in Catalysis

    • 1 Edición
    • Volumen 51
    • Inglés
    Catalysis is the acceleration of a chemical reaction by a catalyst, a substance that notably affects the rate of a chemical reaction without itself being consumed or altered. Since 1948, Advances in Catalysis has filled the gap between the papers that report on and the textbooks that teach in the diverse areas of catalysis research. The editors of and contributors to Advances in Catalysis are dedicated to recording progress in this area.

  • Thermodynamics, Solubility and Environmental Issues

    • 1 Edición
    • Trevor Letcher
    • Inglés
    Environmental problems are becoming an important aspect of our lives as industries grow apace with populations throughout the world. Thermodynamics, Solubility and Environmental Issues highlights some of the problems and shows how chemistry can help to reduce these them. The unifying theme is Solubility – the most basic and important of thermodynamic properties. This informative book looks at the importance and applications of solubility and thermodynamics, in understanding and in reducing chemical pollution in the environment. Written by experts in their respective fields and representing the latest findings in this very important and broad area. A collection of twenty-five chapters cover a wide range of topics including; mining, polymer manufacture and applications, radioactive wastes, industries in general, agro-chemicals, soil pollution and biology, together with the basic theory and recent developments in the modelling of environmental pollutants.

  • Introduction to Diffusion Tensor Imaging

    • 1 Edición
    • Susumu Mori
    • Inglés
    The concept of Diffusion Tensor Imaging (DTI) is often difficult to grasp, even for Magnetic Resonance physicists. Introduction to Diffusion Tensor Imaging uses extensive illustrations (not equations) to help readers to understand how DTI works. Emphasis is placed on the interpretation of DTI images, the design of DTI experiments, and the forms of application studies. The theory of DTI is constantly evolving and so there is a need for a textbook that explains how the technique works in a way that is easy to understand - Introduction to Diffusion Tensor Imaging fills this gap.

  • Alkaloids - Secrets of Life:

    Aklaloid Chemistry, Biological Significance, Applications and Ecological Role
    • 1 Edición
    • Tadeusz Aniszewski
    • Inglés
    Alkaloids, represent a group of interesting and complex chemical compounds, produced by the secondary metabolism of living organisms in different biotopes. They are relatively common chemicals in all kingdoms of living organisms in all environments. Two hundred years of scientific research has still not fully explained the connections between alkaloids and life.Alkaloids-Chemi... Biological Significance, Applications and Ecological Role provides knowledge on structural typology, biosynthesis and metabolism in relation to recent research work on alkaloids. Considering an organic chemistry approach to alkaloids using biological and ecological explanation. Within the book several questions that persist in this field of research are approached as are some unresearched areas. The book provides beneficial text for an academic and professional audience and serves as a source of knowledge for anyone who is interested in the fascinating subject of alkaloids. Each chapter features an abstract. Appendices are included, as are a listing of alkaloids, plants containing alkaloids and some basic protocols of alkaloid analysis.

  • Advances in Heterocyclic Chemistry

    • 1 Edición
    • Volumen 93
    • Alan R. Katritzky
    • Inglés
    Established in 1960, Advances in Heterocyclic Chemistry is the definitive serial in the area—one of great importance to organic chemists, polymer chemists, and many biological scientists. Written by established authorities in the field, the comprehensive reviews combine descriptive chemistry and mechanistic insight and yield an understanding of how the chemistry drives the properties.

  • Tellurium in Organic Synthesis

    Second, Updated and Enlarged Edition
    • 2 Edición
    • Nicola Petragnani + 1 más
    • Inglés
    The increasing number of publications that use tellurium clearly demonstrates the important role of tellurium compounds as unique and powerful tools in a broad range of organic chemical manipulations, often characterized by their selective behavior. Tellurium in Organic Synthesis provides an overview of the principal aspects of organic tellurium chemistry. Many chapters have been enriched and updated in this second edition. New chapters include overviews of toxicology and pharmacology and a review on the preparation and reactivity of several tellurium heterocycles. The first part of the book focuses on the preparation of selected inorganic tellurium compounds and on the main classes of organotellurium compounds. The second part, and main interest of the book, details the use of these inorganic and organic compounds as reagents to perform specific organic manipulations and synthesis. Reactions covered include reduction, formation and reaction of anionic species, deprotection, tellurium cyclizations, formation of alkenes, use of vinyllic tellurides, free radical chemistry, transmetallations, and removal of tellurium.

  • Physics for Chemists

    • 1 Edición
    • Ruslan P. Ozerov + 1 más
    • Inglés
    The development of science, technology and industry in the near future requires new materials and devices, which will differ in many aspects from that of past years. This is due to the fact that many sophisticated processes and new materials are being invented. The computer engineering field is a typical example. The main building block for these achievements is science, and leading it is physics, which provides the foundation for the chemical, biological and atomic industries.Physics for Chemists contains many instructive examples complete with detailed analysis and tutorials to evaluate the student's level of understanding. Specifically it is focused to give a robust and relevant background to chemistry students and to eliminate those aspects of physics which are not relevant to these students.This book is aimed at chemistry students and researches who would by using the book, not only be able to perform relevant physical experiments, but would then also be in a position to provide a well founded explanation of the results.

  • In-situ Spectroscopic Studies of Adsorption at the Electrode and Electrocatalysis

    • 1 Edición
    • Shi-Gang Sun + 2 más
    • Inglés
    In-Situ Spectroscopic Studies of Adsorption at the Electrode and Electrocatalysis is a new reference on in-situ spectroscopic techniques/applicati... fundamentals of electrocatalysis at molecule level, and progresses within electrochemical surface science. Presenting both essential background knowledge at graduate level and original research within the fields of spectroscopy, electrochemistry, and surface science. Featuring 15 chapters by prominent worldwide scholars, based on their recent progress in different aspects of in-situ spectroscopy studies, this book will appeal to a wide audience of scientists. In summary this book is highly suitable for graduates learning basic concepts and advanced applications of in-situ spectroscopy, electrocatalysis and electrode adsorptions.

  • Progress in Medicinal Chemistry

    • 1 Edición
    • Volumen 45
    • F.D. King + 1 más
    • Inglés
    The success of any drug discovery project relies upon the quality of the lead that initiates the lead optimization process. What defines a ‘quality lead’, where these ‘quality leads’ come from and how one discovers them has been the subject of intense debate within the pharmaceutical industry, relies upon defining those properties that historically have led to successful drug discovery. This volume addresses these questions and specifically discusses diabetes, obesity and tuberculosis.

  • Nano Biophotonics

    Science and Technology
    • 1 Edición
    • Volumen 3
    • Hiroshi Masuhara + 2 más
    • Inglés
    This third volume in the series represents the Proceedings of the 3rd International Nanophotonics Symposium, July 6-8, 2006, Icho-Kaikan, Osaka University, Osaka, Japan. Over a two-day symposium, distinguished scientists from around the world convened to discuss the latest progress in this field and the conclusions have been summarised in Nano Biophotonics: Science and Technology. The contents of this book have been compiled by invited lecturers, research members of the relevant projects/program, and some of general participants. The book has 27 chapters which are classified into 4 parts; nano bio-spectroscopy, nano bio-dynamics, nano bio-processing, and nano bio-devices.

  • Industrial Applications of Batteries

    From Cars to Aerospace and Energy Storage
    • 1 Edición
    • Michel Broussely + 1 más
    • Inglés
    Industrial Applications of Batteries looks at both the applications and the batteries and covers the relevant scientific and technological features. Presenting large batteries for stationary applications, e.g. energy storage, and also batteries for hybrid vehicles or different tools. The important aerospace field is covered both in connection with satellites and space missions. Examples of applications include, telecommunications, uninterruptible power supplies, systems for safety/alarms, car accessories, toll collection, asset tracking systems, medical equipment, and oil drilling.The first chapter on applications deals with electric and hybrid vehicles. Four chapters are devoted to stationary applications, i.e. energy storage (from the electric grid or solar/wind energy), load levelling, telecommunications, uninterruptible power supplies, back-up for safety/alarms. Battery management by intelligent systems and prediction of battery life are dealt with in a dedicated chapter. The topic of used battery collection and recycling, with the description of specific treatments for the different systems, is also extensively treated in view of its environmental relevance. Finally, the world market of these batteries is presented, with detailed figures for the various applications.

  • Handbook of Microdialysis

    Methods, Applications and Perspectives
    • 1 Edición
    • Volumen 16
    • Inglés
    Microdialysis is currently one of the most important in vivo sampling methods in physiology and pharmacology. It is used to determine the chemical components of the fluid in the extracellular space of tissues. The technique is now well established in neuroscience research and is used excessively in behavioral neuroscience to determine the concentrations and identities of molecules in brain tissues, and their change due to behavior, hormonal and transmitter changes in the nervous system. The book provides a detailed comprehensive overview of the technology and its applications, including application in pathology, drug development, and the application in the clinic. The authors are all well known researchers in Neuroscience and experts in the use of Microdialysis. Organized into two parts of seven sections, the Handbook of Microdialysis critically examines recent developments in the field through a variety of chapters written by an internationally acclaimed group of authors. It is the first comprehensive handbook covering the technology of Microdialysis and its applications in Neuroscience.

  • Tip Enhancement

    • 1 Edición
    • Inglés
    This book discusses the recent advances in the area of near-field Raman scattering, mainly focusing on tip-enhanced and surface-enhanced Raman scattering. Some of the key features covered here are the optical structuring and manipulations, single molecule sensitivity, analysis of single-walled carbon nanotubes, and analytic applications in chemistry, biology and material sciences. This book also discusses the plasmonic materials for better enhancement, and optical antennas. Further, near-field microscopy based on second harmonic generation is also discussed. Chapters have been written by some of the leading scientists in this field, who present some of their recent work in this field.

  • Annual Reports on NMR Spectroscopy

    • 1 Edición
    • Volumen 60
    • Graham A. Webb
    • Inglés
    Nuclear magnetic resonance (NMR) is an analytical tool used by chemists and physicists to study the structure and dynamics of molecules. In recent years, no other technique has grown to such importance as NMR spectroscopy. It is used in all branches of science where precise structural determination is required and where the nature of interactions and reactions in solution is being studied. Annual Reports on NMR has established itself as a premier means for the specialist and nonspecialist alike to become familiar with new techniques and applications of NMR spectroscopy.

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