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Elsevier

Libros en Inmunología

  • Advances in Immunology

    • 1 Edición
    • Volumen 97
    • Frederick W. Alt
    • Inglés
    Advances in Immunology, a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for future research.

  • Endocrine Manifestations of Systemic Autoimmune Diseases

    • 1 Edición
    • Volumen 9
    • Inglés
    This book is one of the first to evaluate the role of Steroids in autoimmune rheumatic diseases from the basic mechanisms to the clinical involvements and focuses on the importance of steroidal hormones in the pathogenesis and therapeutic management of the autoimmune rheumatic diseases. In particular, the chapters analyze the mechanisms of action and the involvement of adrenal steroids (glucocorticoids) in the neuroendocrine immune system, including effects on the elderly. The perturbations of the HPA axis as a source of altered steroidal synthesis will be discussed and related to some interesting pathological conditions that commonly complicate the autoimmune rheumatic diseases such as psychosis or fibromyalgia. Concerning the role of gonadal steroids (sex hormones), several chapters will discuss clinical and epidemiological evidences of their role, as well as their effects as risk factors in autoimmune rheumatic diseases, including a section on pediatrics.

  • Primer to The Immune Response

    • 1 Edición
    • Tak W. Mak + 2 más
    • Inglés
    Primer to The Immune Response is an invaluable resource for college students, university undergraduates and students in medicine and other health professions who need a concise but complete and understandable introduction to immunology. This book is written in the same engaging conversational style as the published reference book The Immune Response: Basic and Clinical Principles and conveys the same fascinating appeal of immunology. The authors bring clarity, readability and continuity of voice to an audience that requires only a brief survey of the most fundamental concepts in basic and clinical immunology. Primer to The Immune Response is beautifully illustrated with over 200 superb figures and 36 full-color plates, and further enhanced by the inclusion of 60 tables and 6 Appendices. Included with purchase of the book is website access to a captivating “Immunomovie"” that truly brings the immune response to pathogens to life. This new and unique immunology textbook compactly but elegantly covers both basic and clinical principles.

  • Digestive Involvement in Systemic Autoimmune Diseases

    • 1 Edición
    • Volumen 13
    • Manuel Ramos-Casals
    • Inglés
    The Digestive System in Systemic Autoimmune Diseases represents the state-of-the-art in the field of digestive disorders in the most common systemic autoimmune diseases.The volume consists of an introductory chapter on imaging techniques in digestive diseases, followed by eight chapters on digestive manifestations in specific systemic autoimmune diseases. The final five chapters deal with digestive diseases with an autoimmune pathogenesis and systemic manifestations.Inter... in scope, the table of contents reads like a Who's who in clinical research on systemic autoimmune diseases. More than 20 contributors from the European Union, the United States, Mexico and South Africa share their knowledge in this detailed volume.

  • Avian Immunology

    • 1 Edición
    • Bernd Kaspers + 1 más
    • Inglés
    The science underpinning avian immunology is crucial to understanding basic immunological principles and the exceptional features of the avian immune system, as different strategies birds have adopted can provide important evolutionary insights. This book provides the most complete picture of the avian immune system so far. The world-wide importance of poultry protein for the human diet, the threat of an avian influenza pandemic and heavy reliance on vaccination to protect commercial flocks world-wide demonstrates the need to review the important practical lessons in disease control presented here.

  • Insect Immunology

    • 1 Edición
    • Nancy E. Beckage
    • Inglés
    Approx.360 pages

  • The Kidney in Systemic Autoimmune Diseases

    • 1 Edición
    • Volumen 7
    • Justin C Mason + 1 más
    • Inglés
    This volume brings together an international group of clinicians and clinical scientists to contribute to a state-of the-art review of the underlying pathogenic mechanisms, methods of clinical assessment, classification and diagnosis of renal disease, combined with a detailed overview of treatment strategies. An essential reference source for all those involved with the care of patients with renal involvement in systemic autoimmune disease, and for those contributing to research into the underlying pathogenic mechanisms in these disorders.

  • Advances in Immunology

    • 1 Edición
    • Volumen 96
    • Frederick W. Alt
    • Inglés
    Advances in Immunology, a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for future research.

  • Pediatrics in Systemic Autoimmune Diseases

    • 1 Edición
    • Volumen 11
    • Rolando Cimaz + 1 más
    • Inglés
    Many of the systemic autoimmune diseases seen in children are different from those seen in adults making them a special problem for physicians and scientists who care for the affected children and study their diseases. Benefiting both pediatric and adult rheumatologists, as well as physicians from other specialties, this volume covers the latest advances in pathogenesis and clinical management of common conditions seen in pediatric rheumatology practices.

  • Advances in Immunology

    • 1 Edición
    • Volumen 95
    • Frederick W. Alt
    • Inglés
    Advances in Immunology, a long established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for future research.

  • The Neurobiology of Multiple Sclerosis

    • 1 Edición
    • Volumen 79
    • Inglés
    Multiple sclerosis (MS) is an immune-mediated neurodegenerative disorder of the human central nervous system (CNS) which usually affects young adults with certain genetic backgrounds who are then exposed to certain precipitating environmental antigen(s). Despite major advances of the past two decades in understanding the pathophysiology of MS, and in spite of the introduction of new immunomodulatory and immuno-suppressive agents which may slow down disease progression and delay the onset of disability, the “cause” and the “cure” for MS remain elusive. This volume of International Review of Neurobiology focuses on MS and related disorders. The volume can be divided into various sections with the main emphasis on MS pathogenesis, clinical features and epidemiology, neuroimaging, and treatment. The ultimate goal of this book is to encourage further research into the pathogenesis of this elusive disease.

  • AID for Immunoglobulin Diversity

    • 1 Edición
    • Volumen 94
    • Frederick W. Alt + 1 más
    • Inglés
    Advances in Immunology, a long established and highly respected serial, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for future research.

  • Cancer Immunotherapy

    Immune Suppression and Tumor Growth
    • 1 Edición
    • George C. Prendergast + 1 más
    • Inglés
    There has been major growth in understanding immune suppression mechanisms and its relationship to cancer progression and therapy. This book highlights emerging new principles of immune suppression that drive cancer and it offers radically new ideas about how therapy can be improved by attacking these principles. Following work that firmly establishes immune escape as an essential trait of cancer, recent studies have now defined specific mechanisms of tumoral immune suppression. It also demonstrates how attacking tumors with molecular targeted therapeutics or traditional chemotherapeutic drugs can produce potent anti-tumor effects in preclinical models. This book provides basic, translational, and clinical cancer researchers an indispensable overview of immune escape as a critical trait in cancer and how applying specific combinations of immunotherapy and chemotherapy to attack this trait may radically improve the treatment of advanced disease.

  • Advances in Cancer Research

    • 1 Edición
    • Volumen 97
    • George F. Vande Woude + 1 más
    • Inglés
    The Advances in Cancer Research series provides invaluable information on the exciting and fast-moving field of cancer research. A very special event the Nobel Minisymposium, “Molecular Oncology – From Bench to Bedside,” held at the Karolinska Instituet, in Stockholm, Sweden, was marked the celebration of George and Eva Klein’s combined 160th birthday. To honor this occasion, this volume brings together contributions by their former students, colleagues and collaborators of the past fifty years into a volume of Advances in Cancer Research dedicated to George and Eva. Over a decade ago, a subdivision of ACR called “Foundations in Cancer Research” was initiated and the tributes honoring the Kleins’ bodies of work presented at the minisymposium are especially appropriate for the series.

  • Advances in Immunology

    • 1 Edición
    • Volumen 93
    • Frederick W. Alt
    • Inglés
    Advances in Immunology, a long established and highly respected serial, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for future research.

  • Autoantibodies

    • 2 Edición
    • M. Eric Gershwin + 3 más
    • Inglés
    Autoantibodies was published and presented in November 2006 at the International Congress of Autoimmunity in Sorrento, a small town in Campania, Italy. The Congress also celebrated the 100th anniversary of the first routine test for autoantibodies. An autoantibody is a type of antibody that is produced by the immune system and that fights one or more of a person’s own proteins. These autoantibodies cause autoimmune diseases such as lupus erythematosus. The authors and editors of this book provide a critical review of autoantibodies and their primary functions. They cite a number of major developments in the field of autoantibodies, including the detection of autoantibodies in which a healthy person is a carrier; the discovery that autoantibodies can be both pathogenic and protective in some cases; and the development of a device that will help monitor and detect a specific autoantibody using a small amount of serum and proteomic arrays. Aside from the pathogenic and protective autoantibodies, the book also discusses irrelevant autoantibodies, as these may be relevant for future research. It also addresses the importance of the autoantibodies in a person’s body. Clinical physicians, as well as scientists interested in the significance of autoantibodies in the human body, will find this book relevant. It will also be of interest to those who suffer from an autoimmune disease.

  • Advances in Immunology

    • 1 Edición
    • Volumen 92
    • Frederick W. Alt
    • Inglés
    Advances in Immunology, a long established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for future research.

  • Interleukins

    • 1 Edición
    • Volumen 74
    • Gerald Litwack
    • Inglés
    First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. In the early days of the serial, the subjects of vitamins and hormones were quite distinct. The Editorial Board now reflects expertise in the field of hormone action, vitamin action, X-ray crystal structure, physiology, and enzyme mechanisms. Under the capable and qualified editorial leadership of Dr. Gerald Litwack, Vitamins and Hormones continues to publish cutting-edge reviews of interest to endocrinologists, biochemists, nutritionists, pharmacologists, cell biologists, and molecular biologists. Others interested in the structure and function of biologically active molecules like hormones and vitamins will, as always, turn to this series for comprehensive reviews by leading contributors to this and related disciplines.

  • Advances in Immunology

    • 1 Edición
    • Volumen 91
    • Frederick W. Alt
    • Inglés
    Advances in Immunology, a long established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for future research.

  • Immunology

    • 1 Edición
    • Werner Luttmann + 3 más
    • Inglés
    Immunology is more than a laboratory manual; it is a strategic guide that provides the reader with tips and tricks for more successful lab experiments. The authors explore the current methodological variety of immunology in a simple manner, addressing the assets and drawbacks as well as critical points. Also provided are short and precise summaries of routine procedures as well as listings of the advantages and disadvantages of alternative methods. This well-written guide is an essential companion for anyone using modern immunological methods in the laboratory.

  • Cancer Immunotherapy

    • 1 Edición
    • Volumen 90
    • James Allison + 1 más
    • Inglés
    For some time immunotherapy has been heralded as a breakthrough approach for cancer treatment. Although the potential of this strategy remains solid, the approach needs considerable refinement. Whilst some programmes are looking to increase the understanding of molecular and cellular mechanisms underlying the stimulation of antitumor immunity, others are trying to find the most appropriate clinical setting that will reveal the role of the immune system in combating cancer. Among the most important discoveries have been tumor-specific antigens. This thematic volume highlights some key issues and discusses where they may move forward. It has been put together by two leading cancer immunotherapists from two eminent institutions that focus on cancer research.

  • The Autoimmune Diseases

    • 4 Edición
    • M. Eric Gershwin + 1 más
    • Inglés
    Since publication of the Third Edition in 1998, the understanding of the immune mechanisms underlying autoimmunity and autoimmune disease has significantly deepened and broadened. This Fourth Edition incorporates new material and combines common themes underlying inductive and effector mechanisms and therapies that relate generally to the autoimmune disorders. It discusses the biological basis of disease at genetic, molecular, cellular, and epidemiologic levels.

  • Advances in Immunology

    • 1 Edición
    • Volumen 89
    • Frederick W. Alt
    • Inglés
    Advances in Immunology, a long established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for future research.

  • The Skin in Systemic Autoimmune Diseases

    • 1 Edición
    • Volumen 5
    • Piercarlo Sarzi-Puttini
    • Piercarlo Sarzi-Puttini + 3 más
    • Inglés
    This book represents the state-of-the-art in the field of skin and autoimmune rheumatic diseases. It covers systematically a growing and multifaceted topic which is of great importance in the clinical practice. It also serves as a sharp educational tool as each chapter provides summaries and specific highlights to key references cited into the text. The pathophysiological link between skin involvement and autoimmunity has been explained in detail, as well as diagnostic and therapeutic aspects.This book yields an impressive body of well ordered information which summarizes the experience of a selected panel of distinguished physicians and scientists actively involved in the field of skin immunology and systemic autoimmunity.

  • Immunopotentiators in Modern Vaccines

    • 1 Edición
    • Virgil E.J.C. Schijns + 1 más
    • Inglés
    Immunopotentiators in Modern Vaccines provides an in-depth insight and overview of a number of most promising immunopotentiators in modern vaccines. In contrast to existing books on the subject it provides recent data on the critical mechanisms governing the activity of vaccine adjuvants and delivery systems. Knowledge of immunological pathways and scenarios of the cells and molecules involved is described and depicted in comprehensive illustrations.

  • Reproductive and Hormonal Aspects of Systemic Autoimmune Diseases

    • 1 Edición
    • Volumen 4
    • Michael Lockshin + 1 más
    • Inglés
    This volume of the Handbook of Systemic Autoimmune Diseases series represents a medical collaboration focusing primarily on female aspects of rheumatic diseases. This collaboration recognizes the need to understand and optimally manage the care of women with autoimmune conditions that may affect their reproduction and hormonal status. This handbook will prove useful to clinicians and researchers alike. It covers practical points, ranging from which anti-rheumatic medications are safe in pregnancy to how to counsel women with scleroderma contemplating pregnancy.

  • The Immune Response

    Basic and Clinical Principles
    • 1 Edición
    • Tak W. Mak + 1 más
    • Inglés
    The Immune Response is a unique reference work covering the basic and clinical principles of immunology in a modern and comprehensive fashion. Written in an engaging conversational style, the book conveys the broad scope and fascinating appeal of immunology. The book is beautifully illustrated with superb figures as well as many full color plates. This extraordinary work will be an invaluable resource for lecturers and graduate students in immunology, as well as a vital reference for research scientists and clinicians studying related areas in the life and medical sciences.

  • Handbook of Immunohistochemistry and in situ Hybridization of Human Carcinomas

    Molecular Genetics: Liver and Pancreatic Carcinomas V3
    • 1 Edición
    • M. A. Hayat
    • Inglés
    Immunohistochemistry is the use of specific antibodies to stain particular molecular species in situ. This technique has allowed the identification of many more cell types than could be visualized by classical histology, particularly in the immune system and among the scattered hormone-secreting cells of the endocrine system, and has the potential to improve diagnosis, prognosis and therapeutic options of cancer. This book discusses all aspects of immunohistochemistry and in situ hybridization technologies and the important role they play in reaching a cancer diagnosis. It provides step-by-step instructions on the methods of additional molecular technologies such as DNA microarrays, and microdissection, along with the benefits and limitations of each method. The topics of region-specific gene expression, its role in cancer development and the techniques that assist in the understanding of the molecular basis of disease are relevant and necessary in science today.

  • Advances in Immunology

    • 1 Edición
    • Volumen 87
    • Frederick W. Alt
    • Inglés
    Advances in Immunology, a long established and highly respected series, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for future research.

  • Natural Immunity

    • 1 Edición
    • Volumen 5
    • Lorand Bertok + 1 más
    • Inglés
    "Natural Immunity" is a broadly-based account of the activities of the evolutionarily conserved molecules, cells and processes of the natural immune system. This encompasses the early host protection against microbes (bacteria and viruses) and tumours, prior to the generation of the adaptive immune response, diverse major current pathologies including inflammatory and autoimmune diseases, and key roles in essential physiological processes such as reproduction and wound healing.

  • Advances in Immunology

    • 1 Edición
    • Volumen 86
    • Frederick W. Alt
    • Inglés
    Advances in Immunology, a long established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for future research.

  • Handbook of Immunohistochemistry and in Situ Hybridization of Human Carcinomas

    Molecular Pathology, Colorectal Carcinoma, and Prostate Carcinoma
    • 1 Edición
    • M. A. Hayat
    • Inglés
    Immunohistochemistry is the use of specific antibodies to stain particular molecular species in situ. This technique has allowed the identification of many more cell types than could be visualized by classical histology, particularly in the immune system and among the scattered hormone-secreting cells of the endocrine system, and has the potential to improve diagnosis, prognosis and therapeutic options of cancer. Handbook of Immunohistochemistry and in Situ Hybridization of Human Carcinomas discusses all aspects of immunohistochemistry and in situ hybridization technologies and the important role they play in reaching a cancer diagnosis. It provides step-by-step instructions on the methods of additional molecular technologies such as DNA microarrays, and microdissection, along with the benefits and limitations of each method. The topics of region-specific gene expression, its role in cancer development and the techniques that assist in the understanding of the molecular basis of disease are relevant and necessary in science today. This book is the second volume of three planned, individually-sold volumes on this topic. Like Volume 1, this book fully explains the principles and applications of modern techniques used in the field of molecular genetics. It will be of particular interest to pathologists and molecular pathologists conducting both academic and/or clinical research.

  • Mucosal Immunology

    • 3 Edición
    • Jiri Mestecky + 6 más
    • Inglés
    Mucosal immunology is so important since most infectious agents enter the body through the various mucous membranes, and many common infections take place in or on mucous membranes. Mucosal Immunology, now in its third edition, is the only comprehensive reference covering the basic science and clinical manifestations of mucosal immunology. This book contains new research data, exceptional illustrations, original theory, a new perspective and excellent organization.

  • Measuring Immunity

    Basic Science and Clinical Practice
    • 1 Edición
    • Michael T. Lotze + 1 más
    • Inglés
    Most of the diseases of modern mankind involve either acute or chronic inflammation. Measuring Immunity integrates the current information available on biomarkers and surrogate assays into a single handbook. It highlights the principles behind various applications, gives a brief summary on how they are conducted and provides detailed and critical analyses of murine models of immunity, clinical trials, and tests to predict utility and benefit. Measuring Immunity is indispensable for scientists and clinicians interested in the clinical applications of modern immunobiology.

  • Hot Spot Pollutants

    Pharmaceuticals in the Environment
    • 1 Edición
    • Inglés
    Hot Spot Pollutants describes how pharmaceuticals and/or endocrine active compounds gain entry into the aquatic ecosystem, effects on specific organisms and the potential risk involved for the whole ecosystem. In addition it presents the latest views and developments regarding legal requirements for assessing the environmental risk of pharmaceuticals. This books includes the views of academic, industry and government scientists, and thus aims for a balanced presentation of all standpoints. The book consists of papers that appeared previously in the journal Toxicology Letters in 2002 and 2003, and have been collected in this single volume to make them accessible to a broader audience. Authors were asked to update their contributions where necessary. See also Toxicology Letters volume 131, issues 1 and 2 (2002), and volume 142 issue 3 (2003).

  • The Neurologic Involvement in Systemic Autoimmune Diseases

    • 1 Edición
    • Volumen 3
    • Inglés
    Systemic autoimmune diseases can affect both the central and peripheral nervous systems in a myriad of ways and through a heterogeneous number of mechanisms leading to many different clinical manifestations. As a result, neurological complications of these disorders can result in significant morbidity and mortality. Advances in the diagnosis, laboratory investigations, and management of these conditions has placed an increasing burden on the practicing clinician to correctly assess and treat these patients.This volume of the Handbook of the Systemic Autoimmune Diseases will help the clinician and researcher better understand the current concepts of nervous system involvement from systemic autoimmune disorders, recognize current approaches to diagnosis and treatment, current controversies, and areas that need significant research efforts. It is believed that providing this approach in a single volume will facilitate its use as a frequent resource for all those caring for or investigating these patients and their diseases.Each chapter follows a consistent outline to provide the reader with important and useful information in an easy-to-navigate manner and is also liberally referenced to provide more primary source material for further consideration. The standardized approach to each chapter will allow the reader to be able to compare and contrast more efficiently the neurological complications of the autoimmune diseases discussed.

  • Infection and Autoimmunity

    • 1 Edición
    • Nancy Agmon-Levin + 2 más
    • Inglés
    Infection and Autoimmunity encompasses the different mechanisms involved in the infection-autoimmuni... association/inductio... Special attention is given to heat shock proteins (HSPs) and to transgenic mouse models to better understand infection-induced autoimmunity. Organized into six parts, this book first discusses the mechanisms of autoimmune induction by infection. Some chapters follow discussing the vaccination and vaccines, including the controversial issue of vaccine-autoimmunity relationship. Other chapters elucidate the relationship of bacteria and parasites to autoimmunity. Lastly, the aspects of infections and diseases are described. This reference material will help readers gain a deeper insight into the important etiological aspects of autoimmunity.

  • Pulmonary Involvement in Systemic Autoimmune Diseases

    • 1 Edición
    • Volumen 2
    • Inglés
    In this book is found the information essential to diagnosing, managing and treating the lung complications of connective tissue diseases. This is a notoriously difficult area, which continues to puzzle clinicians, despite the fact that these disorders are increasingly frequent (as a result of longer survival in connective tissue disease). In separate chapters, the major connective tissue diseases are reviewed, with detailed discussion of a variety of lung abnormalities, including pleural disease, parenchymal lung disease and pulmonary vascular disease. There are also invaluable overviews of lung histological and CT appearances in these disorders, and a deeply insightful chapter on drug-induced lung disease in connective tissue disease. The emphasis in this book is on accuracy of evaluation and the construction of a logical management plan, based on disease severity and intrinsic progressiveness.

  • Immunology Guidebook

    • 1 Edición
    • Julius Cruse + 2 más
    • Inglés
    The Immunology Guidebook provides an easily accessible text-reference to the more up-to-date and difficult concepts in the complex science of immunology. It aims to demystify basic concepts and specialised molecular and cellular interactions. Its 18 chapters offer a logical and sequential presentation where much of the data is displayed in carefully designed tables. This book is intended for immunology students, researchers, practitioners and basic biomedical scientists.

  • Advances in Immunology

    • 1 Edición
    • Volumen 84
    • Frederick W. Alt
    • Inglés
    Advances in Immunology presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for future research.

  • T Cell Subsets

    Cellular Selection, Commitment and Identity
    • 1 Edición
    • Volumen 83
    • Inglés
    This first thematic issue, of the Advances in Immunology series, highlights the remarkable new insights into the mechanisms that govern development and function of T cell lineages. Recent developments in the understanding of the genetic and epigenetic mechanisms that regulate development of the two major T cell lineages will have a fundamental impact on a number of research fields -immunology, cell biology, hematology and stem cell research. All of these groups have a vested interest in comprehending issues such as stem cell self renewal, progenitor plasticity, lineage commitment and cellular identity. Immunologists have a special interest in the mechanisms that allow selection of a T cell repertoire whose members integrate genetic information for T cell receptor, co-receptor and specialized immunologic function, since this process lies at the core of adaptive immunity.T Cell Subsets is a timely and invaluable review for immunologists, cell biologists hematologists and stem cell researchers

  • Handbook of Immunohistochemistry and in Situ Hybridization of Human Carcinomas

    Molecular Genetics; Lung and Breast Carcinomas
    • 1 Edición
    • M. A. Hayat
    • Inglés
    The various cell types have traditionally been recognized and classified according to their appearance in the light microscope following the process of fixing, processing, sectioning, and staining tissues that is known as histology. Classical histology has been augmented by immunohistochemistry (the use of specific antibodies to stain particular molecular species in situ). Immunohistochemistry has allowed the identification of many more cell types than could be visualized by classical histology, particularly in the immune system and among the scattered hormone-secreting cells of the endocrine system. Handbook of Immunohistochemistry and in Situ Hybridization of Human Carcinomas discusses all aspects of immunohistochemistry and in situ hybridization technologies and the important role they play in reaching a cancer diagnosis. It provides step-by-step instructions on the methods of additional molecular technologies such as DNA microarrays, and microdissection, along with the benefits and limitations of each method. The topics of region-specific gene expression, its role in cancer development and the techniques that assist in the understanding of the molecular basis of disease are relevant and necessary in science today, ensuring a wide audience for this book.

  • Advances in Immunology

    • 1 Edición
    • Volumen 82
    • Frederick W. Alt
    • Inglés
    Advances in Immunology presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for future research.

  • The Heart in Systemic Autoimmune Diseases

    • 1 Edición
    • Volumen 14
    • Andrea Dorea
    • Inglés
    This first volume represents the state-of-the-art in the field of cardiovascular disease and autoimmune rheumatic diseases. Systemic autoimmune diseases comprise a family of conditions that share common pathogenetic mechanisms as well as a multi-organ involvement including the heart. This volume has been subdivided into three parts. In the first part, the immune mechanisms involved in cardiac damage have been considered. The role of proinflammatory and regulatory cytokines in driving an autoimmune response to cardiac self-tissues has been analysed. Moreover, the prevalence, the clinical meaning and the hypothetical pathogenicity of a broad spectrum of organ and non-organ specific autoantibodies have been discussed in detail. In the second part of the volume, the role of humoral and innate immunity in promoting the development of atherosclerotic plaque has been extensively reviewed, along with the newly discovered anti-inflammatory properties of statins. These two parts of the volume deal with exciting aspects of this topic, suggesting a very close connection between heart diseases and immunology. Finally, in the third part, the cardiac manifestations observed in the major systemic autoimmune conditions have been comprehensively examined.This book yields an impressive body of well ordered information, highlighting key references and summarising the experience of a selected panel of distinguished physician-scientists actively involved in the field of cardiovascular disease and systemic autoimmunity.

  • The Flaviviruses: Pathogenesis and Immunity

    • 1 Edición
    • Volumen 60
    • Inglés
    Over 50% of known flaviviruses have been associated with human disease. The Flavivirus genus constitutes some of the most serious human pathogens including Japanese encephalitis, dengue and yellow fever. Flaviviruses are known for their complex life cycles and epidemic spread, and are considered a globally-emergent viral threat.Pathogenesis and Immunity, the second volume of The Flaviviruses, examines the processes by which the flaviviruses cause disease, the different cytopathic effects and the associated immunopathological responses produced in their hosts.

  • Advances in Immunology

    • 1 Edición
    • Volumen 81
    • Inglés
    Volume 81 of Advances in Immunology contains articles on a vast range of immunology topics including the regulation of the immune response by the interaction of chemokines and proteases as well as roles of the Semaphorin Family in immune regulation. It has a chapter devoted to B Lymphoid Neoplasms of Mice and another on the Zebrafish as a model organism to study development of the immune system. This volume will be of interest to immunologists in all industries.

  • Advances in Parasitology

    • 1 Edición
    • Volumen 56
    • Inglés
    Advances in Parasitology is a serial containing in-depth reviews on current topics of interest in contemporary parasitology. It includes medical studies on parasites of major influence, such as trypanosomiasis and scabies, and more traditional areas, such as zoology, taxonomy, and life history, which shape current thinking and applications.

  • The Blood Group Antigen FactsBook

    • 2 Edición
    • Marion E. Reid + 1 más
    • Inglés
    The second edition of The Blood Group Antigen FactsBook provides key information relating to human red blood cell membrane components carrying blood group antigens, the molecular basis of the antigens, their serological characteristics, and the clinical significance of blood group antibodies. The data on this group of molecules has expanded greatly since the previous edition was published five years ago. Topics include: history and information on terminology, expression, chromosomal assignment, carrier molecule description, molecular basis of antigens, effect of enzymes/chemicals, clinical significance, disease association, phenotypes, glycotypes and key references.

  • Antigenic Variation

    • 1 Edición
    • Alister G. Craig + 1 más
    • Inglés
    The topic of antigenic variation is important in both biology and medicine. It is of enormous interest, as it describes the process(es) whereby microorganisms 'shift shape', by genetic rearrangement or otherwise. In medical terms, this has a major impact on the infectious disease process, since the immune system has great difficulty in keeping up with this variation, and thus eliminating the infectious agent. Antigenic variation is a major method by which microbes evade the immune response, and persist in the body.The broad scope of the book appeals to all those working in the field of infectious disease, immunology of infection, pathogenesis, molecular biology and also to evolutionary biologists. Topics covered include not only bacterial species, and viruses such as influenza, HIV, Rotavirus, but also eukaryotic parasites - one of the most fascinating groups of organisms exhibiting this behaviour.

  • Neurobiology of the Immune System

    • 1 Edición
    • Volumen 52
    • Angela Clow + 1 más
    • Inglés
    Published since 1959, International Review of Neurobiology is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research.

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