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Elsevier

Libros en Aplicaciones

  • Modern Bioinformatics

    From Molecular Insights to Biomedical Innovation
    • 1 Edición
    • Kolla Bhanu Prakash + 2 más
    • Inglés
    Modern Bioinformatics: From Molecular Insights to Biomedical Innovation explores the rapidly advancing field of bioinformatics, addressing a critical gap in current literature by integrating quantum biology and quantum biosensors with computational bioinformatics. The book offers a thorough exploration of bioinformatics from foundational concepts to translational applications. It begins with molecular structures of proteins, DNA, and RNA, advancing through nano-molecular visualization and structural domain analysis. Readers gain insights into deep learning techniques like AlphaFold for protein structure prediction, AI applications in genomics, and molecular interactions critical to function. The text further covers computational methods in drug discovery, forensic bioinformatics, and molecular evolution.A unique emphasis is placed on the convergence of nanotechnology and quantum innovations in molecular diagnostics and biosensing, including quantum biosensors and quantum computing applications. The final sections focus on computational strategies for drug target identification, biomarker discovery, and clinical trial analysis, providing a holistic view of modern bioinformatics workflows. This book is an indispensable reference for advanced researchers, graduate students, and professionals in bioinformatics, molecular biology, and biomedical engineering seeking to integrate quantum computing and nanotechnology into their work.

  • Advanced Computational and Mathematical Approaches in Applied Differential Equations

    • 1 Edición
    • Snehashish Chakraverty + 2 más
    • Inglés
    Advanced Computational and Mathematical Approaches in Applied Differential Equations explores cutting-edge techniques and methodologies in solving complex differential equations, a cornerstone of mathematical modeling across science and engineering. The book bridges theory and application, offering advanced computational strategies and innovative mathematical insights to address real-world problems. Beginning with an overview that presents a unified framework that defines the types of differential equations covered (e.g. ordinary, partial, fractional, fuzzy), the book then progresses to foundations and methods such as Lie symmetries, homotropy, Adomian, FEM, FDM, spectral, machine learning, fuzzy, and fractional derivatives, addressing both computational and mathematical dimensions.Different... equations are fundamental to modeling complex systems, yet solving them often involves significant challenges due to their complexity and nonlinearity. The book equips readers with advanced tools and methodologies to overcome these challenges, providing innovative solutions that improve accuracy, efficiency, and applicability in real-world scenarios. Ideal for researchers, practitioners, and advanced students, it provides a comprehensive resource for tackling challenging applied differential equations with better precision and efficiency.

  • Complexity in Mathematical Biology for Sustainable Development

    Modeling Climate, Disease, and Ecosystems through Difference, Differential, and Fractional Theory
    • 1 Edición
    • Fatma Bozkurt
    • Inglés
    Complexity in Mathematical Biology for Sustainable Development: Modeling Climate, Disease, and Ecosystems through Difference, Differential, and Fractional Theory introduces new mathematical methods to derive complex modeling solutions for a wide range of engineering and scientific research applications. The book strikes a balance between high-level mathematical theory and technical derivations, offering step-by-step explanations, real-world case studies, and clear introductions to advanced mathematical models. Solutions include modeling and quantifying complexity, with emphasis placed on the growing need for interdisciplinary collaboration, the integration of real-time data into models, and the development of adaptive frameworks challenges such as pandemics, biodiversity loss, and climate uncertainty.The book is designed to meet the needs of a diverse primary audience, from graduate students to professionals in fields such as computer science, public health, environmental policy, applied mathematics, and biotechnology. By providing both theoretical foundations and practical applications, the book equips readers with the skills and knowledge to tackle pressing global challenges through mathematical models, making it a valuable resource for both academic and professional development.

  • Up and Running with AutoCAD 2027

    2D and 3D Drawing, Design and Modeling
    • 1 Edición
    • Robert C. Kaebisch + 1 más
    • Inglés
    Up and Running with AutoCAD® 2027: 2D and 3D Drawing, Design and Modeling presents a combination of step-by-step instructions, examples, and insightful explanations. The book emphasizes core concepts and practical application of AutoCAD in engineering, architecture, and design. To improve student learning, the book's early chapters have been revised and expanded with additional assignments, more explicit step-by-step guidance for the earliest assignments, improved readability, and a new concise drafting fundamentals reference section that focuses on orthographic projection, basic standards, and naming conventions.Equally useful in instructor-led classroom training, self-study, or as a professional reference, the book is written by a long-time AutoCAD professor and instructor with the user in mind

  • Up and Running with AutoCAD 2026

    2D and 3D Drawing, Design and Modeling
    • 1 Edición
    • Robert C. Kaebisch + 1 más
    • Inglés
    Up and Running with AutoCAD 2026: 2D and 3D Drawing, Design and Modeling presents a combination of step-by-step instructions, examples, and insightful explanations. The book emphasizes core concepts and practical application of AutoCAD in engineering, architecture, and design. Equally useful in instructor-led classroom training, self-study, or as a professional reference, the book is written by a long-time AutoCAD professor and instructor with the user in mind.

  • Medical Oncology Compendium

    • 1 Edición
    • Ramon Andrade B de Mello
    • Inglés
    Medical Oncology Compendium discusses several important topics in oncology with the help of leading experts worldwide who incorporate not only knowledge on recent developments in the field, but contextualize them within diverse socioeconomic environments to guarantee the applicability of the content in challenging scenarios. The book comprehensively discusses topics such as surgery, radiology, carcinogenesis, screening, assessment tools, evidence-based medicine, and precision oncology as applicable to different cancer types as non-small and small cell lung cancer, mesothelioma, breast cancer, gastric-rectal cancer, female specific cancers, prostate, skin and bone sarcomas.In addition, it discusses options to minimize oncology pain and palliative care. It is a valuable resource for oncologists, clinicians, researchers, healthcare workers and members of biomedical field who needs to understand more about diagnosis, treatment options and support for cancer patients.

  • Encyclopedia of Bioinformatics and Computational Biology

    • 2 Edición
    • Shoba Ranganathan + 2 más
    • Inglés
    Bioinformatics and Computational Biology (BCB) combine elements of computer science, information technology, mathematics, statistics, and biotechnology, providing the methodology and in silico solutions to mine biological data and processes, for knowledge discovery.In the era of molecular diagnostics, targeted drug design, translational medicine and Big Data for personalized medicine, computational methods for data analysis are essential tools for biochemistry, biology, biotechnology, pharmacology, biomedical and computer science, as well as mathematics and statistics. New areas are emerging, and relatively isolated fields are becoming current hot research areas in BCB, such as Artificial Intelligence, Quantitative Biology, Computational Vaccinology, Epidemiology and Infection Diffusion, Synthetic Biology, and Phenomics. The role of BCB in characterizing SARS-CoV-2 variants and facing the COVID-19 pandemic is just one example of how these tools can help us better prepare for such future events.This Encyclopedia comprises three sections, covering Methods, Topics, and Applications. The methodologies and algorithms underpinning BCB are described in the Methods section; Topics covers traditional areas such as phylogeny, as well as more recent areas such as translational bioinformatics, cheminformatics and environmental informatics; Applications provides guidance for commonly asked “how to” questions.Navigating the maze of confusing jargon and the plethora of software tools is often confronting for students and researchers alike. This comprehensive and unique resource provides up-to-date theory and application content to address molecular data analysis requirements, with precise definitions of terminology and lucid explanations by field experts.

  • Advances in Computational Methods and Modeling for Science and Engineering

    • 1 Edición
    • Hari M Srivastava + 2 más
    • Inglés
    Advances in Computational Methods and Modelling in Science and Engineering explores the application of computational techniques and modeling approaches in science and engineering, providing practical knowledge and skills for tackling complex problems using numerical simulations and data analysis. This book addresses the need for a cohesive and up-to-date resource in the rapidly evolving field of computational methods. It consolidates diverse topics, serving as a one-stop guide for individuals seeking a comprehensive understanding of the subject matter. Sections focus on mathematical techniques that provide global solutions for models arising in engineering and scientific research applications by considering their long-term benefits.The mathematical treatment of these models is very helpful in understanding these models and their real-world applications. The methods and modeling techniques presented are useful for mathematicians, engineers, scientists, and researchers working on the mathematical treatment of models in a wide range of applications, including disciplines such as engineering, physics, chemistry, computer science, and applied mathematics.

  • Agent-Based Models with MATLAB

    • 1 Edición
    • Erik Cuevas + 3 más
    • Inglés
    Agent-Based Models with MATLAB introduces Agent-Based Modeling (ABM), one of the most important methodologies for complex systems modeling. The book explores computational implementations and accompanying MATLAB software code as a means of inspiring readers to apply agent-based models to solve a diverse range of problems. It comes with a large amount of software code that accompanies the main text, and the modeling systems described in the book are implemented using MATLAB as the programming language. Despite the heavy mathematical components of Agent-Based Models and complex systems, it is possible to utilize these models without in-depth understanding of their mathematical fundamentals.This book enables computer scientists, mathematicians, researchers, and engineers to apply ABM in a wide range of research and engineering applications. It gradually advances from basic to more advanced methods while reinforcing complex systems through practical, hands-on applications of various computational models.

  • Advances in Cancer Biomarkers Research

    • 1 Edición
    • Anand Narayan Singh + 2 más
    • Inglés
    Advances in Cancer Biomarkers Research provides a thorough and detailed description of cancer biomarkers for diagnostic, prognostic and therapeutics in several cancer types. The book presents a compendium of topics related to current advanced research, along with fundamental knowledge that will help readers fully comprehend the field of cancer biomarkers. Topics discussed include such the role of genetic mechanisms, epigenetics, DNA and microRNA in different cancers, signaling pathways and exosomes. In addition, the book discusses biomarker research applied to several cancer types, such as head and neck, urological, lung, bone tumors, hematological and neurological malignancies and breast cancers.This will be a valuable resource for cancer researchers, oncologists, graduate students and members of the biomedical field who are interested in the potential of biomarkers in cancer research and treatment.

  • Systematic Review and Meta-Analysis

    Stepwise Approach for Medical and Biomedical Researchers
    • 1 Edición
    • Mahsa Ghajarzadeh + 2 más
    • Inglés
    Systematic Review and Meta-Analysis: Stepwise Approach for Medical and Biomedical Researchers presents a step-by-step approach to develop systematic reviews and meta-analysis for biomedical and medical research. Systematic reviews are the highest quality evidence in medical research, providing an answer to a specific question, and they can be developed in the form of comprehensive literature search, critical appraisal, and synthesis of the evidence. Systematic reviews and meta-analysis are key elements of evidence-based medicine by summarizing the results of previous studies with the use of specific and reliable methods.Initially, systematic review and meta-analysis were exclusive to clinical trials, however systematic reviews of observational and diagnostic studies have expanded, making it essential for members of the field to master those techniques. This practical reference is a valuable resource for biostaticians, researchers, students, and members of medical and biomedical fields who need to understand more about systematic reviews and meta-analysis in their research work.

  • Fixed Point Optimization Algorithms and Their Applications

    • 1 Edición
    • Watcharaporn Cholamjiak
    • Inglés
    Fixed Point Optimization Algorithms and Their Applications discusses how the relationship between fixed point algorithms and optimization problems is connected and demonstrates hands-on applications of the algorithms in fields such as image restoration, signal recovery, and machine learning. The book is divided into nine chapters beginning with foundational concepts of normed linear spaces, Banach spaces, and Hilbert spaces, along with nonlinear operators and useful lemmas and theorems for proving the book’s main results. The author presents algorithms for nonexpansive and generalized nonexpansive mappings in Hilbert space, and presents solutions to many optimization problems across a range of scientific research and real-world applications. From foundational concepts, the book proceeds to present a variety of optimization algorithms, including fixed point theories, convergence theorems, variational inequality problems, minimization problems, split feasibility problems, variational inclusion problems, and equilibrium problems. Fixed Point Optimization Algorithms and Their Applications equips readers with the theoretical mathematics background and necessary tools to tackle challenging optimization problems involving a range of algebraic methods, empowering them to apply these techniques in their research, professional work, or academic pursuits.

  • Therapeutic Applications of Nitric Oxide in Cancer and Inflammatory Disorders

    Third International Conference on Therapeutic Application of Nitric Oxide in Cancer and Inflammatory Disorders
    • 1 Edición
    • Valentina Rapozzi + 2 más
    • Inglés
    Therapeutic Applications of Nitric Oxide in Cancer and Inflammatory Disorders: Third International Conference on Therapeutic Application of Nitric Oxide in Cancer and Inflammatory Disorders presents updated information on the chemistry, signaling of newly derived therapeutic nitric oxide donors/inhibitors, and their complexes in liposomes or nanospheres in both preclinical and clinical investigations.This book consists of the following: The program and abstracts presented at the Third International Conference in Udine, Italy, September 3-5, 2023; Parts I–V review on (I) the general properties of nitric oxide in diseases; (II) the role of nitric oxide in cancer; (III) nitric oxide and immunity; (IV) nitric oxide and aging; and (V) nitric oxide and therapeutics. In addition, part VI is an educational review on artificial intelligence and its application in diseases. These updated reviews present many examples of research investigations related to the application of novel therapeutic compounds on nitric oxide and new derivatives, as well as their significant therapeutic activities against various resistant cancers that are unresponsive to current treatments and in different inflammatory disorders.This book is a valuable resource for cancer researchers, oncologists, graduate students, and investigators from medical and biomedical fields who want to learn more about NO and its therapeutic applications in cancer and inflammatory diseases. This book is also highly useful for both clinicians and oncologists as well as pharmaceutical companies involved in the development of new anticancer/antiinfla... agents.

  • A Practical Introduction to Virtual Reality

    From Concepts to Executables
    • 1 Edición
    • Lori Rebenitsch + 2 más
    • Inglés
    A Practical Introduction to Virtual Reality: From Concepts to Executables is written for the undergraduate computer science student taking a course in virtual reality. This tutorial-based text is organized so that by the end of the semester students will have created their first VR game, including sound and various interactions. The materials are written from the position of the student and the student’s professor as opposed to the professional with prior graphics experience.Beginning with an introductory chapter covering the ten universal basics necessary for VR coding, the book moves on to such topics as putting together a VR set-up, creating Heads Up displays, building scene trees, learning how to import 3D models and animations, lighting and audio, and more, until by the end of the book, students will have a final project game ready for beta testing and publishing!

  • Computational Modeling Applications for Climate Crisis

    • 1 Edición
    • Utku Kose + 2 más
    • Inglés
    Computational Modeling Applications for Climate Crisis provides readers with innovative research on the applications of computational modeling to moderate climate change. The book begins with an overview and history of climate change, followed by several chapters covering the concepts of computational modeling and simulation, including parameters of climate change, modeling the effects of human activities, visualization tools, and data fusion for advanced modeling applications. It then proceeds to cover decision support systems, modeling of technological solutions for climate change, modeling of greenhouse gas emissions, tracking of climate factors, and modeling of earth resources. In the final chapters of the book, the authors cover nation-based outcomes, big data, and optimization solutions with real-world data and case studies. Climate change is one of the most pressing existential issues for humans and the planet, and this book covers leading-edge applications of computational modeling to the vast array of interdisciplinary factors and challenges posed by climate change. As life itself is a mixture of occurrences that can be mathematically modelled, it is important to work with specific parameters, which are critical for monitoring and controlling the dynamics of the earth, natural resources, technological factors, and human activities.

  • The Evolution of Immunotherapy Against Tumors

    An Historical Approach
    • 1 Edición
    • Domenico Ribatti
    • Inglés
    The Evolution of Immunotherapy Against Tumors: An Historical Approach summarizes the literature concerning the development of the theory of immune surveillance against tumors. It discusses the evidence for and against this theory, along with the concept of immunoediting. Finally, current approaches in anti-tumor immunotherapy will be analyzed.The immune system plays a major role in the surveillance against tumors. To avoid attack from the immune system, tumor cells develop different strategies to escape immune surveillance. Evidence of immune surveillance comes from both animal models and clinical observations. Mice with a wide variety of immunodeficiencies have a high rate of tumor incidence and are more susceptible to transplanted or chemical carcinogen-induced tumors. Immunosuppressed patients have a high incidence of tumors. However, many patients develop cancer even in the presence of an apparently normal immune system. This indicates that tumor cells can escape immune surveillance.

  • Caspases as Molecular Targets for Cancer Therapy

    • 1 Edición
    • Ankur Vaidya
    • Inglés
    Caspases as Molecular Targets for Cancer Therapy discusses the recent developments on targeted therapies for cancer using caspases. It describes the selection of specific caspases for cancer therapy with the current standard of care and highlights numerous assay techniques for caspase activities. This book discusses topics such as mutations within apoptosis gene, inflammatory caspases, tumor suppression, and the different caspase types and their role in anticancer activity. In addition, it discusses caspase activity assay procedure and future perspectives. It is a valuable resource for researchers, students, and members of biomedical and medical fields who want to learn more about novel anticancer targeted therapies.

  • Cancer Epigenetics and Nanomedicine

    Targeting the Right Player via Nanotechnology
    • 1 Edición
    • Prashant Kesharwani + 1 más
    • Inglés
    Cancer Epigenetics and Nanomedicine: Targeting the Right Player via Nanotechnology is a complete package that provides a comprehensive and thorough understanding of the key players that modulate the various steps of carcinogenesis and malignant progression of the disease and the critical targets to be exploited for developing novel modalities of diagnosis and therapeutics.Since epigenetic aberrations can be potentially reversed and restored to their normal state through epigenetic therapy, the book also discusses the challenges and the future of the field with the cutting-edge revelations and limitations that this research endeavor can offer, thereby helping the readers to enhance their critical thinking and adopt strategies of therapeutic importance.

  • Pathophysiology and Treatment of Atherosclerotic Disease in Peripheral Arteries

    • 1 Edición
    • Aloke Virmani Finn
    • Inglés
    Pathophysiology and Treatment of Atherosclerotic Disease in Peripheral Arteries is a thorough review of the disease written by experts studying its detection and treatment. These state-of-the-art chapters summarize emerging knowledge about this important area of medicine. The pathophysiology and treatment of peripheral artery (PAD) disease remains poorly understood even by practitioners. Often it is assumed that PAD should be treated in a similar fashion to coronary artery disease (CAD), when in fact recent data suggest a distinct pathophysiology with genetic risk having some but not complete overlap with CAD.This is a novel reference of emerging data on the factors behind its development and progression, detection, and treatment suggest an emerging paradigm for this disease.

  • Application of Artificial Intelligence in Early Detection of Lung Cancer

    • 1 Edición
    • Madhuchanda Kar + 3 más
    • Inglés
    Application of Artificial Intelligence in Early Detection of Lung Cancer presents the most up-to-date computer-aided diagnosis techniques used to effectively predict and diagnose lung cancer. The presence of pulmonary nodules on lung parenchyma is often considered an early sign of lung cancer, thus using machine and deep learning technologies to identify them is key to improve patients’ outcome and decrease the lethal rate of such disease. The book discusses topics such as basics of lung cancer imaging, pattern recognition techniques, deep learning, and nodule detection and localization. In addition, the book discusses risk prediction based on radiological analysis and 3D modeling.This is a valuable resource for cancer researchers, oncologists, graduate students, radiologists, and members of biomedical field who are interested in the potential of AI technologies in the diagnosis of lung cancer.

  • Bio-Inspired Strategies for Modeling and Detection in Diabetes Mellitus Treatment

    • 1 Edición
    • Alma Y Alanis + 3 más
    • Inglés
    Bio-Inspired Strategies for Modeling and Detection in Diabetes Mellitus Treatment focuses on bioinspired techniques such as modeling to generate control algorithms for the treatment of diabetes mellitus. The book addresses the identification of diabetes mellitus using a high-order recurrent neural network trained by an extended Kalman filter. The authors also describe the use of metaheuristic algorithms for the parametric identification of compartmental models of diabetes mellitus widely used in research works such as the Sorensen model and the Dallaman model. In addition, the book addresses the modeling of time series for the prediction of risk scenarios such as hyperglycaemia and hypoglycaemia using deep neural networks. The detection of diabetes mellitus in the early stages or when current diagnostic techniques cannot detect glucose intolerance or prediabetes is proposed, carried out by means of deep neural networks present in the literature. Readers will find leading-edge research in diabetes identification based on discrete high-order neural networks trained with an extended Kalman filter; parametric identification of compartmental models used to describe diabetes mellitus; modeling of data obtained by continuous glucose-monitoring sensors for the prediction of risk scenarios such as hyperglycaemia and hypoglycaemia; and screening for glucose intolerance using glucose-tolerance test data and deep neural networks. Application of the proposed approaches is illustrated via simulation and real-time implementations for modeling, prediction, and classification.

  • Current Molecular Targets of Heterocyclic Compounds for Cancer Therapy

    • 1 Edición
    • Vivek Asati + 1 más
    • Inglés
    Current Molecular Targets of Heterocyclic Compounds for Cancer Therapy discusses recently developed treatments based on molecular targets which are genetically altered in cancer cells and are essential for tumor development and survival. Considerable research effort has been devoted to the development of targeted drugs that inhibit the action of pathogenic kinases, and clinical studies performed so far have validated the positive effects of kinase inhibitors for cancer treatment. Each chapter discusses a molecular target, such as ALK2, ATR, CK, Src-Abl, EGFR, Fyn-Blk-Lyn, IGFs, and PAK1.The book's chapters are written by experts who actively work on the targets to help readers fully understand how they can be used. This is a valuable resource for cancer researchers, oncologists, graduate students and members of the biomedical field who are interested in the potential of novel cancer therapies based on molecular targets.

  • The Metaverse and Smart Cities

    Urban Environments in the Age of Digital Connectivity
    • 1 Edición
    • Zaheer Allam + 1 más
    • Inglés
    The Metaverse and Smart Cities: Urban Environments in the Age of Digital Connectivity explores the intersection between the rapidly growing metaverse and the future of cities. The metaverse is a virtual world that is increasingly gaining attention as a new frontier for human interaction and commerce. At the same time, cities are undergoing significant transformation as they face challenges such as population growth, urbanization, and environmental degradation. Urban planners and city administrators will find valuable insights on how the metaverse can be integrated into the planning and development of smart, sustainable, and future cities.The book begins with an introduction to the concepts and technology of the metaverse as well as its history. It then sheds light on the current and future challenges and opportunities that the metaverse presents to cities and the quality of life of urban dwellers. It delves into the ways in which the metaverse can change cities, both in terms of their physical and virtual environments, and the impact it can have on the lives of those who live in them. It brings together the latest research and perspectives from experts in the fields of virtual reality, urban planning, and sustainability, to provide a comprehensive and up-to-date picture of this rapidly evolving field.

  • Curcumin-Based Nanomedicines as Cancer Therapeutics

    • 1 Edición
    • Amirhossein Sahebkar + 1 más
    • Inglés
    Curcumin-based Nanomedicines as Cancer Therapeutics presents a consistent and thorough overview of nanocurcumin applications in cancer treatments. It brings together the novel applications of nanocurcumin in biological milieu as well as helps readers to define the major gaps in knowledge that can lead to significant scientific discoveries.Nanocurc... has been widely explored for the treatment of various cancers; however, the scientific literature is inconsistent in style and structure and scattered across many sources. By providing an explicit account on vital aspects on nanocurcumin-based anticancer delivery approaches and discussing the perspectives of the technologies explored so far based upon the findings outlined, the book offers updated and in-depth knowledge on the topic in one single source written by global leading experts.In addition, the book aims to stimulate the interest of the academic researchers, industrial scientists, businessmen, and young scholars to address key multidisciplinary challenges faced by nanotechnologists to foster the desired collaboration among biologists, chemists, physicists, engineers, and clinicians to find proper and efficient new cancer treatments.

  • Fractional Difference, Differential Equations, and Inclusions

    Analysis and Stability
    • 1 Edición
    • Saïd Abbas + 3 más
    • Inglés
    Fractional Difference, Differential Equations, and Inclusions: Analysis and Stability is devoted to the existence and stability (Ulam-Hyers-Rassias stability and asymptotic stability) of solutions for several classes of functional fractional difference equations and inclusions. Covered equations include delay effects of finite, infinite, or state-dependent nature, and tools used to establish the existence results for the proposed problems include fixed point theorems, densifiability techniques, monotone iterative technique, notions of Ulam stability, attractivity and the measure of non-compactness, as well as the measure of weak noncompactness. The tools of fractional calculus are found to be of great utility in improving the mathematical modeling of many natural phenomena and processes occurring in the areas of engineering, social, natural, and biomedical sciences. All abstract results in the book are illustrated by examples in applied mathematics, engineering, biomedical, and other applied sciences.

  • Multifunctional Nanocomposites for Targeted Drug Delivery in Cancer Therapy

    • 1 Edición
    • Awesh K. Yadav + 2 más
    • Awesh K. Yadav + 2 más
    • Inglés
    Multifunctional Nanocomposites for Targeted Drug Delivery in Cancer Therapy explores the design, synthesis, and application of different multifunctional nanocomposites drug delivery system for cancer treatment. It encompasses initial chapters discussing introductory information about cancer, followed by chapters focusing on the detailed information about various novel drug delivery systems for treatment of several organ site cancers such as prostate, skin, breast, lung, liver, pancreas, stomach, colon, blood, mouth and throat. It is a valuable resource for cancer researchers, oncologists, graduate students, and members of biomedical research who need to understand more about novel nanotechnologies applied to cancer treatment.

  • Colorectal Cancer

    Disease and Advanced Drug Delivery Strategies
    • 1 Edición
    • Bhupendra G. Prajapati + 2 más
    • Inglés
    Colorectal Cancer: Disease and Advanced Drug Delivery Strategies examines the combined impact of basic clinical and medical treatments as well as recent advances in the field of colorectal cancer. With a strong focus towards colorectal cancer diagnosis, disease drug delivery, and diagnosis, the book also examines the Tumor microenvironment-res... and site-specific nanoparticles for cancer theragnostics. Sections provide the opportunity to understand and diagnose the disease, describes screening methods, and update on drugs, including nano- and immunotherapy. Content includes clinical trials in colorectal cancer research and disease models that help better direct researchers and clinicians on how to diagnose and treat colorectal cancer.

  • Biomarkers in Cancer Detection and Monitoring of Therapeutics

    Volume 2: Diagnostic and Therapeutic Applications
    • 1 Edición
    • Ranbir Chander Sobti + 2 más
    • Inglés
    Molecular Biomarkers in Cancer Detection and Monitoring of Therapeutics: Volume Two: Diagnostic and Therapeutic Applications discusses how molecular biomarkers are used to determine predisposition, facilitate detection, improve treatment and offer prevention guidelines for different cancers. It focuses on novel diagnostic techniques based on molecular biomarkers and their impact on treatment, covering different cancer types such as tumors in the nervous system, head and neck, oral and GI tractor, lung, breast, gastric system, leukemia and urogenital tract cancers. For each type, the book discusses the best diagnostic techniques and therapeutic approaches, thus helping readers easily identify the best solution for each case. This is a valuable resource for cancer researchers, oncologists, graduate students and other members of the biomedical field who are interested in the potential of biomarkers in cancer research.

  • Biomarkers in Cancer Detection and Monitoring of Therapeutics

    Volume 1: Discovery and Technologies
    • 1 Edición
    • Ranbir Chander Sobti + 2 más
    • Inglés
    Biomarkers in Cancer Detection and Monitoring of Therapeutics, Volume One, Discovery and Technologies discusses how molecular biomarkers are used to determine predisposition, facilitate detection, improve treatment and offer prevention guidelines for different cancer types. This first volume in the series focuses on techniques and approaches recently developed to assist in the decision of which biomarker to use for specific conditions. Topics covered include circulating tumor cells and circulating tumor DNA, exomes, tumor microenvironment, gene editing, artificial intelligence and robotics. In addition, the book discusses the development and applications of organoids and precision medicine.This book will be a valuable resource for cancer researchers, oncologists, graduate students and members of the biomedical field who are interested in the potential of biomarkers in cancer research.

  • Recent Advances in Nanocarriers for Pancreatic Cancer Therapy

    • 1 Edición
    • Prashant Kesharwani + 1 más
    • Inglés
    Recent Advances in Nanocarriers for Pancreatic Cancer Therapy reviews thriving strategies concerning pancreatic cancer therapy, thoroughly describing the most recent developments in emerging modern drug delivery systems focused on, and derived from, nanotechnology. By providing a holistic understanding of the molecular pathways, conventional therapy and novel nanocarriers mediated drug delivery against pancreatic cancer, this work can be considered a complete package. The book offers a solution to the dissemination of data from a broad range of resources by providing an overview of the molecular pathways and conventional therapy of pancreatic cancer, the application of various nanocarriers, and more. This book equips scientists, clinicians and students to make rational treatment approaches based on nanomedicine for improving and extending the human life against pancreatic cancer.

  • Resistance to Anti-CD20 Antibodies and Approaches for Their Reversal

    • 1 Edición
    • Volumen 2
    • Inglés
    Resistance to Anti-CD20 Antibodies and Approaches for Their Reversal presents in-depth content written by international experts in the study of resistance to anti-CD20 antibodies and approaches for their reversal. Anti-CD20 antibodies are used to achieve B cell depletion and are developed to treat B cell proliferative disorders, including non-Hodgkin’s lymphoma and chronic lymphocytic leukemia. In the past two decades, anti-CD20 antibodies have revolutionized the treatment of all B cell malignancies, however, there are patients that fail to respond to initial therapy or relapse sooner. This book explores new and existing avenues surrounding Anti-CD20 antibodies. In recent years, several next-generation anti-CD20 therapies have been developed but predicting and reversing resistance is still a challenging task. These areas are being actively studied as they represent a potential to improve anti-CD20 therapies and are discussed thoroughly in the book. It is a valuable resource for researchers, students and member of the biomedical and medical fields who want to learn more about resistance to anti-CD20 antibodies and their reversal.

  • pH Deregulation as the Eleventh Hallmark of Cancer

    • 1 Edición
    • Tomas Koltai + 6 más
    • Inglés
    pH Deregulation as the Eleventh Hallmark of Cancer presents key concepts about pH deregulation in a concise and straight-forward manner. The book discusses topics such as pH regulation and metabolism, sodium hydrogen exchanger, monocarboxylate transporter, V-ATPase proton pump, carbonic anhydrases, and voltage gated sodium channels. In addition, it covers clinical and therapeutic implications and future perspectives. This is a valuable resource for researchers, oncologists, students and members of the biomedical and medical fields who want to learn more about the role of pH deregulation in cancer treatment. pH deregulation can improve the outcome of classical treatments without adding toxicity to them, and the book shows that treating the pH peculiarities of cancer is simple and can be performed with existing drugs. Based on the classification of tumor malignancy in ten hallmarks, the authors put pH deregulation at the spotlight and separated from metabolic reprogramming due to its impact on all other hallmarks, proposing it as an additional characteristic to evaluate and fight cancer.

  • Multi-Criteria Decision-Making Sorting Methods

    Applications to Real-World Problems
    • 1 Edición
    • Luis Martinez Lopez + 3 más
    • Inglés
    Multi Criteria Decision Making (MCDM) is a generic term for all methods that help people making decisions according to their preferences, in situations where there is more than one conflicting criterion. It is a branch of operational research dealing with finding optimal results in complex scenarios including various indicators, conflicting objectives and criteria. The approach of MCDM involves decision making concerning quantitative and qualitative factors.　　 The importance and success of MCDM are due to the fact that they have successfully dealt with different types of problematics for supporting decision makers such as choice, ranking and sorting, description.　　 Even though, each of the different problematics in MCDM is important, Multi-Criteria Decision-Making Sorting Methods will focus on sorting approaches across a wide range of interesting techniques and research disciplines. The applications which have been and can be solved by these techniques are more and more important in current real-world decision-making problems. Therefore, the book provides a clear overview of MCDM sorting methods and the different tools which can be used to solve real-world problems by revising such tools and characterizing them according to their performance and suitability for different types of problems. The book is aimed at a broad audience including computer scientists, engineers, geography and GIS experts, business and financial management experts, environment experts, and all those professional people interested in MCDM and its applications. The book may also be useful for teaching MCDM courses in fields such as industrial management, computer science, and applied mathematics, as new developments in multi-criteria decision making.

  • Biostatistics Manual for Health Research

    A Practical Guide to Data Analysis
    • 1 Edición
    • Nafis Faizi + 1 más
    • Inglés
    **Selected for 2026 Doody's Core Titles in Biostatistics**Biost... Manual for Health Research: A Practical Guide to Data Analysis is a guide for researchers on how to apply biostatistics on different types of data. The book approaches biostatistics and its application from medical and health researcher’s point-of-view and has real and mostly published data for practice and understanding. The interpretation and meaning of the statistical results, reporting guidelines and mistakes are taught with real world examples. This is a valuable resource for biostaticians, students and researchers from medical and biomedical fields who need to learn how to apply statistical approaches to improve their research.

  • Nitric Oxide in Health and Disease

    Therapeutic Applications in Cancer and Inflammatory Disorders
    • 1 Edición
    • Lucia Morbidelli + 2 más
    • Inglés
    Approx.326 pages

  • Up and Running with AutoCAD® 2024

    2D and 3D Drawing, Design and Modeling
    • 1 Edición
    • Elliot J. Gindis + 1 más
    • Inglés
    Up and Running with AutoCAD® 2024: 2D and 3D Drawing, Design and Modeling presents a combination of step-by-step instructions, examples and insightful explanations. The book emphasizes core concepts and practical application of AutoCAD in engineering, architecture and design. Equally useful in instructor-led classroom training, self-study or as a professional reference, the book is written by a long-time AutoCAD professor and instructor with the user in mind.

  • Computational Methods in Drug Discovery and Repurposing for Cancer Therapy

    • 1 Edición
    • Ganji Purnachandra Nagaraju + 2 más
    • Inglés
    Computational Methods in Drug Discovery and Repurposing for Cancer Therapy provides knowledge about ongoing research as well as computational approaches for drug discovery and repurposing for cancer therapy. The book also provides detailed descriptions about target molecules, pathways, and their inhibitors for easy understanding and applicability. The book discusses tools and techniques such as integrated bioinformatics approaches, systems biology tools, molecular docking, computational chemistry, artificial intelligence, machine learning, structure-based virtual screening, biomarkers, and transcriptome; those are discussed in the context of different cancer types, such as colon, pancreatic, glioblastoma, endometrial, and retinoblastoma, among others. This book is a valuable resource for researchers, students, and members of the biomedical and medical fields who want to learn more about the use of computational modeling to better tailor the treatment for cancer patients.

  • Network Algorithmics

    An Interdisciplinary Approach to Designing Fast Networked Devices
    • 2 Edición
    • George Varghese + 1 más
    • Inglés
    Network Algorithmics: An Interdisciplinary Approach to Designing Fast Networked Devices, Second Edition takes an interdisciplinary approach to applying principles for efficient implementation of network devices, offering solutions to the problem of network implementation bottlenecks. In designing a network device, there are dozens of decisions that affect the speed with which it will perform – sometimes for better, but sometimes for worse. The book provides a complete and coherent methodology for maximizing speed while meeting network design goals. The book is uniquely focused on the seamless integration of data structures, algorithms, operating systems and hardware/software co-designs for high-performance routers/switches and network end systems. Thoroughly updated based on courses taught by the authors over the past decade, the book lays out the bottlenecks most often encountered at four disparate levels of implementation: protocol, OS, hardware and architecture. It then develops fifteen principles key to breaking these bottlenecks, systematically applying them to bottlenecks found in end-nodes, interconnect devices and specialty functions located along the network. Later sections discuss the inherent challenges of modern cloud computing and data center networking.

  • Health Information Exchange

    Navigating and Managing a Network of Health Information Systems
    • 2 Edición
    • Brian Dixon
    • Inglés
    Health Information Exchange: Navigating and Managing a Network of Health Information Systems, Second Edition, now fully updated, is a practical guide on how to understand, manage and make use of a health information exchange infrastructure, which moves patient-centered information within the health care system. The book informs and guides the development of new infrastructures as well as the management of existing and expanding infrastructures across the globe. Sections explore the reasons for the health information exchange (HIE) infrastructures, how to manage them, examines the key drivers of HIE, and barriers to their widespread use. In addition, the book explains the underlying technologies and methods for conducting HIE across communities as well as nations. Finally, the book explains the principles of governing an organization that chiefly moves protected health information around. The text unravels the complexities of HIE and provides guidance for those who need to access HIE data and support operations.

  • Understanding Personalisation

    New Aspects of Design and Consumption
    • 1 Edición
    • Iryna Kuksa + 2 más
    • Inglés
    Understanding Personalization: New Aspects of Design and Consumption addresses the global phenomenon of personalization that affects many aspects of everyday life. The book identifies the dimensions of personalization and its typologies. Issues of privacy, the ethics of design, and the designer/maker’s control versus the consumer’s freedom are covered, along with sections on digital personalization, advances in new media technologies and software development, the way we communicate, our personal devices, and the way personal data is stored and used. Other sections cover the principles of personalization and changing patterns of consumption and development in marketing that facilitate individualized products and services. The book also assesses the convergence of both producers and consumers towards the co-creation of goods and services and the challenges surrounding personalization, customization, and bespoke marketing in the context of ownership and consumption.

  • Role of Tumor Microenvironment in Breast Cancer and Targeted Therapies

    • 1 Edición
    • Manzoor Ahmad Mir
    • Inglés
    Role of Tumor Microenvironment in Breast Cancer and Targeted Therapies discusses the current understanding of breast cancer tumor microenvironment components, their role in tumorigenicity and the development of therapeutic resistance, along with updates on recent advances.

  • Up and Running with AutoCAD 2023

    2D and 3D Drawing, Design and Modeling
    • 1 Edición
    • Elliot J. Gindis + 1 más
    • Inglés
    Up and Running with AutoCAD 2023: 2D and 3D Drawing, Design and Modeling presents a combination of step-by-step instruction, examples and insightful explanations. The book emphasizes core concepts and practical applications of AutoCAD in engineering, architecture and design. Equally useful in instructor-led classroom training, self-study, or as a professional reference, the book is written by a long-time AutoCAD professor and instructor with the user in mind.

  • Contemporary Management of Metastatic Colorectal Cancer

    A Precision Medicine Approach
    • 1 Edición
    • Aslam Ejaz + 1 más
    • Inglés
    Contemporary Management of Metastatic Colorectal Cancer: A Precision Medicine Approach summarizes current knowledge and provides evidenced-based practice recommendations on how to treat patients with metastatic colorectal cancer. The book presents topics such as pre-operating imaging, the use of molecular markers in treatment decisions, neoadjuvant therapy, synchronous colorectal liver metastasis, and minimally invasive approaches. In addition, it discusses immunotherapy, targeted therapies and survivorship. This is a valuable resource for practitioners, cancer researchers, oncologists, graduate students and members of biomedical research who need to understand more about novel treatments for colorectal cancer metastasis.

  • Essential MATLAB for Engineers and Scientists

    • 8 Edición
    • Daniel T. Valentine + 1 más
    • Inglés
    Essential MATLAB for Engineers and Scientists, Eighth Edition provides a concise and balanced overview of MATLAB's functionality, covering both fundamentals and applications. The essentials are illustrated throughout, featuring complete coverage of the software's windows and menus. Program design and algorithm development are presented, along with many examples from a wide range of familiar scientific and engineering areas. This edition has been updated to include the latest MATLAB versions through 2021a. This is an ideal book for a first course on MATLAB, but is also ideal for an engineering problem-solving course using MATLAB.

  • Industrial Tomography

    Systems and Applications
    • 2 Edición
    • Mi Wang
    • Inglés
    Industrial Tomography: Systems and Applications, Second Edition thoroughly explores the important techniques of industrial tomography, also discusses image reconstruction, systems, and applications. This book presents complex processes, including the way three-dimensional imaging is used to create multiple cross-sections, and how computer software helps monitor flows, filtering, mixing, drying processes, and chemical reactions inside vessels and pipelines. This book is suitable for materials scientists and engineers and applied physicists working in the photonics and optoelectronics industry or in the applications industries.

  • Theranostics and Precision Medicine for the Management of Hepatocellular Carcinoma, Volume 3

    Translational and Clinical Outcomes
    • 1 Edición
    • Ganji Purnachandra Nagaraju + 1 más
    • Inglés
    Theranostics and Precision Medicine for the Management of Hepatocellular Carcinoma: Translational and Clinical Outcomes, Volume Three provides comprehensive information about ongoing research and clinical data on liver cancer. The book presents detailed descriptions about diagnostics and therapeutic options for easy understanding, with a focus on precision medicine approaches to improve treatment outcomes. This updated volume discusses topics such as clinical and safety assessment of HCC patients, liver transplantation as a therapeutic option, immunotherapy interventions, and image-based surveillance. In addition, it discusses immunohistology of HCC-enabled precision medicine and artificial intelligence for hepatocellular carcinomas. This is a valuable resource for cancer researchers, oncologists, graduate students, hepathologists and members of biomedical research who need to understand more about liver cancer to apply in their research work or clinical setting.

  • Current Trends and Advances in Computer-Aided Intelligent Environmental Data Engineering

    • 1 Edición
    • Goncalo Marques + 1 más
    • Inglés
    Current Trends and Advances in Computer-Aided Intelligent Environmental Data Engineering merges computer engineering and environmental engineering. The book presents the latest finding on how data science and AI-based tools are being applied in environmental engineering research. This application involves multiple domains such as data science and artificial intelligence to transform the data collected by intelligent sensors into relevant and reliable information to support decision-making. These tools include fuzzy logic, knowledge-based systems, particle swarm optimization, genetic algorithms, Monte Carlo simulation, artificial neural networks, support vector machine, boosted regression tree, simulated annealing, ant colony algorithm, decision tree, immune algorithm, and imperialist competitive algorithm. This book is a fundamental information source because it is the first book to present the foundational reference material in this new research field. Furthermore, it gives a critical overview of the latest cross-domain research findings and technological developments on the recent advances in computer-aided intelligent environmental data engineering.

  • Cognitive and Soft Computing Techniques for the Analysis of Healthcare Data

    • 1 Edición
    • Akash Kumar Bhoi + 3 más
    • Inglés
    Cognitive and Soft Computing Techniques for the Analysis of Healthcare Data discusses the insight of data processing applications in various domains through soft computing techniques and enormous advancements in the field. The book focuses on the cross-disciplinary mechanisms and ground-breaking research ideas on novel techniques and data processing approaches in handling structured and unstructured healthcare data. It also gives insight into various information-processi... models and many memories associated with it while processing the information for forecasting future trends and decision making. This book is an excellent resource for researchers and professionals who work in the Healthcare Industry, Data Science, and Machine learning.

  • Anomaly Detection and Complex Event Processing Over IoT Data Streams

    With Application to eHealth and Patient Data Monitoring
    • 1 Edición
    • Patrick Schneider + 1 más
    • Inglés
    Anomaly Detection and Complex Event Processing over IoT Data Streams: With Application to eHealth and Patient Data Monitoring presents advanced processing techniques for IoT data streams and the anomaly detection algorithms over them. The book brings new advances and generalized techniques for processing IoT data streams, semantic data enrichment with contextual information at Edge, Fog and Cloud as well as complex event processing in IoT applications. The book comprises fundamental models, concepts and algorithms, architectures and technological solutions as well as their application to eHealth. Case studies, such as the bio-metric signals stream processing are presented –the massive amount of raw ECG signals from the sensors are processed dynamically across the data pipeline and classified with modern machine learning approaches including the Hierarchical Temporal Memory and Deep Learning algorithms. The book discusses adaptive solutions to IoT stream processing that can be extended to different use cases from different fields of eHealth, to enable a complex analysis of patient data in a historical, predictive and even prescriptive application scenarios. The book ends with a discussion on ethics, emerging research trends, issues and challenges of IoT data stream processing.

  • Cybersecurity for Connected Medical Devices

    • 1 Edición
    • Arnab Ray
    • Inglés
    The cybersecurity of connected medical devices is one of the biggest challenges facing healthcare today. The compromise of a medical device can result in severe consequences for both patient health and patient data.　Cybersecurity for Connected Medical Devices covers all aspects of medical device cybersecurity, with a focus on cybersecurity capability development and maintenance, system and software threat modeling, secure design of medical devices, vulnerability management, and integrating cybersecurity design aspects into a medical device manufacturer's Quality Management Systems (QMS). This book is geared towards engineers interested in the medical device cybersecurity space, regulatory, quality, and human resources specialists, and organizational leaders interested in building a medical device cybersecurity program.