Saltar al contenido principal
Elsevier

Libros en Ciencias de la Vida

  • COVID-19 in New York City

    Public Health Crisis and its Aftermath
    • 1 Edición
    • Rainer W.G. Gruessner
    • Inglés
    COVID-19 in New York City: A Five-Year Account presents a comprehensive account of the pandemic, from how events unfolded, how circumstances were handled, and how New Yorkers learned to better manage a similarly deadly pandemic in the future. The book documents the period from when the first case was diagnosed in New York City, addressing the medical, political, social, psychological, business, and environmental aspects, as well as the changes in behavior and lifestyle. The author shares his birds eye view of the city through a comprehensive investigation of the events, and the impact of the current and future implications for all readers.This book serves as a guide for anyone interested in how to handle and cope with a future deadly pandemic or similar disaster and is written by a physician and advocate for science who was living in New York City during the pandemic.

  • AI and Precision Oncology

    Innovations in Diagnosis and Drug Development
    • 1 Edición
    • Arun Kumar Singh + 2 más
    • Inglés
    AI and Precision Oncology: Innovations in Diagnosis and Drug Development examines the transformative role of artificial intelligence and machine learning in oncology. The book addresses the urgent need for early cancer diagnosis and effective therapeutic treatments, highlighting how technological advancements enable rapid analysis of large datasets to enhance patient outcomes. The content explores clinical applications of next-generation sequencing (NGS) integrated with AI technologies, covering risk prediction, disease detection, biomarker identification, and therapeutic target discovery. The book emphasizes the importance of bioinformatics tools in analyzing NGS data and showcases AI-powered applications that improve cancer diagnosis and prognostication.For the academic audience, this book provides valuable insights into the latest advancements in AI and precision oncology. It equips researchers and clinicians with knowledge on personalized treatment strategies and recent clinical studies, ultimately enhancing understanding of how AI can revolutionize cancer care and improve patient management.

  • Advances in Applied Microbiology

    • 1 Edición
    • Volumen 135
    • Inglés
    Advances in Applied Microbiology, Volume 133 presents a comprehensive exploration of the latest innovations in applied microbiology. The book delves into the diverse applications of microbiology across various industries, including agriculture, food production, biotechnology, environmental science, and healthcare. Chapters in this new release include Advances in production related petroleum microbiology, Degradation of Steroid Four-Ring Structures by Comamonas testosteroni: Similar Mechanisms Observed in Various Bacteria Including Mycobacterium tuberculosis, Detoxification of mycotoxins by microorganisms, Use of Deep Eutectic Solvents in Microbial Technology, and more.Through a collection of insightful chapters authored by experts in the field, readers are offered in-depth analyses of cutting-edge research, emerging trends, and practical applications of microbiological principles. From novel microbial technologies to the impact of microbiomes on human health and beyond, this book serves as a valuable resource for researchers, professionals, and students seeking to stay informed and inspired by the exciting advancements.

  • The Matrix Metalloproteinases

    • 1 Edición
    • Volumen 60
    • Inglés
    The Matrix Metalloproteinases, Volume 60 in The Enzymes series, explores recent advances in the study of matrix metalloproteinases (MMPs), a critical family of enzymes involved in extracellular matrix remodeling and numerous physiological and pathological processes. This volume presents a comprehensive collection of chapters covering key aspects of MMP biology, including their structure, function, regulation, and detection through activity-based probes.Chapters in this release examine classical and selective MMP inhibitors, including specific targeting strategies for MMP-13, as well as the role of endogenous tissue inhibitors of metalloproteinases. Additional contributions explore the involvement of MMPs in various biological and disease contexts, including oral diseases, neurodegenerative disorders, neutrophil biology, and cancer progression.The volume also addresses current challenges and opportunities in the design of MMP-targeted therapeutics, highlighting advances in drug development and pharmacological applications. Together, these chapters provide valuable insights into the biochemical, physiological, and clinical significance of MMPs, making this volume an essential reference for researchers in enzymology, biochemistry, molecular biology, and biomedical sciences.

  • Modern Bioinformatics

    From Molecular Insights to Biomedical Innovation
    • 1 Edición
    • Kolla Bhanu Prakash + 2 más
    • Inglés
    Modern Bioinformatics: From Molecular Insights to Biomedical Innovation explores the rapidly advancing field of bioinformatics, addressing a critical gap in current literature by integrating quantum biology and quantum biosensors with computational bioinformatics. The book offers a thorough exploration of bioinformatics from foundational concepts to translational applications. It begins with molecular structures of proteins, DNA, and RNA, advancing through nano-molecular visualization and structural domain analysis. Readers gain insights into deep learning techniques like AlphaFold for protein structure prediction, AI applications in genomics, and molecular interactions critical to function. The text further covers computational methods in drug discovery, forensic bioinformatics, and molecular evolution.A unique emphasis is placed on the convergence of nanotechnology and quantum innovations in molecular diagnostics and biosensing, including quantum biosensors and quantum computing applications. The final sections focus on computational strategies for drug target identification, biomarker discovery, and clinical trial analysis, providing a holistic view of modern bioinformatics workflows. This book is an indispensable reference for advanced researchers, graduate students, and professionals in bioinformatics, molecular biology, and biomedical engineering seeking to integrate quantum computing and nanotechnology into their work.

  • Acute Myocardial Infarction in Young Women

    Understanding its Mechanisms and Management
    • 1 Edición
    • Stéphane Peggy Manzo-Silberman
    • Inglés
    Acute Myocardial Infarction in Young Women: Understanding its Mechanisms and Management serves as a seminal reference for understanding the current landscape of cardiovascular health in young women, highlighting clinical areas that require focused attention. By customizing the information to their unique physiological and clinical differences, more precise and effective interventions will lead to improved outcomes. The information is meticulously updated to address the specific cardiovascular health issues encountered by young women with myocardial infarction. This ensures that each stage of care—from cardiovascular risk assessment and symptom-recognition to the acute myocardial infarction (AMI) pathway, and rehabilitation follow-up—is optimized.Ultimately... this book equips health professionals with the most current and evidence-based information, enabling them to deliver the highest standard of care for young women with myocardial infarction. It will enhance quality of care, and contribute to improved health outcomes for young women across all stages of the cardiovascular healthcare continuum.

  • AI-Driven Diagnostics for 6G-Enabled Smart Healthcare

    • 1 Edición
    • Sangeeta Kumari + 3 más
    • Inglés
    AI-Driven Diagnostics for 6G-Enabled Smart Healthcare explores the transformative integration of artificial intelligence (AI) and next-generation 6G networks in the healthcare sector. The book begins by highlighting the evolution of healthcare technology and the critical role of AI-driven diagnostics, emphasizing how 6G facilitates real-time, ultra-reliable communication. Key features of 6G, such as ultra-low latency and massive connectivity are discussed, showcasing their impact on advanced healthcare applications like remote diagnostics and patient monitoring. In addition, the integration of AI in medical diagnostics is examined, focusing on machine learning and deep learning techniques that enhance disease detection through medical imaging and clinical data analysis.Users will also find content that explores the benefits of remote patient monitoring, particularly for underserved populations, and delves into edge AI for localized, low-latency diagnostic processing. Other sections cover real-time imaging diagnostics are highlighted and address predictive analytics, detailing AI models that forecast diseases and the role of IoT devices and wearables in healthcare diagnostics. Final sections cover ethical considerations and regulatory challenges.

  • Integrating AI in Psychological and Mental Health Care

    Techniques, Applications, and Ethical Considerations
    • 1 Edición
    • Sandeep Kautish + 4 más
    • Inglés
    Integrating AI in Psychological and Mental Health Care: Techniques, Applications, and Ethical Considerations introduces key concepts and the historical evolution of AI, providing a foundation for understanding its applications in mental health. The content delves into various aspects of AI, including diagnostic tools, machine learning algorithms, and natural language processing, highlighting their roles in enhancing therapeutic outcomes and improving patient care. The discussion encompasses significant mental health conditions such as anxiety, depression, and severe psychological disorders, showcasing how AI technologies can assist in diagnosis, treatment planning, and monitoring. Ethical considerations and privacy issues are critically examined, ensuring a balanced perspective on the benefits and challenges associated with AI-driven interventions. Practical applications, such as virtual psychotherapists and AI-enhanced cognitive behavioral therapy illustrate real-world implementations and their impact on patient care. Additionally, case studies provide insights into successful AI applications in mental health settings, thus enhancing our understanding of potential advantages and obstacles.

  • Ecology of Marine Rocky Shores

    • 1 Edición
    • Volumen 105
    • Inglés
    Ecology of Marine Rocky Shores, Volume 105 in the Advances in Marine Biology series, highlights new advances in the field, presenting comprehensive chapters written by an international board of authors. This volume explores key ecological processes shaping rocky shore environments, including the impacts of plastic pollution, the dynamics of warm-temperate and subtropical systems, and the roles of foundation species and community interactions.Additio... chapters examine conservation planning, kelp ecology and restoration, fisheries and indigenous knowledge, and the influence of ocean rafting on species distribution. The volume also addresses spatial and network approaches to ecology, coastal marine microbiology, and the ecological impacts of invasive species. Together, these contributions provide an integrated perspective on the structure, function, and resilience of rocky shore ecosystems, offering valuable insights for researchers, marine ecologists, and environmental scientists.

  • Alternative Splicing

    Recent Advances in Health and Disease
    • 1 Edición
    • Sayeed ur Rehman A. Kalam + 1 más
    • Inglés
    Alternative Splicing: Recent Advances in Health and Disease offers a comprehensive study of this cellular process, its fundamental characteristics, latest advances, and clinical utilization. Opening with an introduction to alternative splicing and its function in generating transcriptome and protein diversity, the book considers the role of this process across a range of diseases and disorders, including cardiovascular disease, cancer, obesity, and viral infections. Key methods used to study alternative splicing are also investigated, including high-throughput sequencing-based methods, bioinformatics tools, computational methods, single-cell sequencing techniques and mass-spectrometry based proteomics.This is followed with analysis of therapeutic approaches associated with alternative splicing. This is an ideal reference for those involved in investigating alternative splicing and its impact to health and disease, and is therefore relevant to researchers across cell biology, molecular biology, pharmacology and related areas.

  • Artificial Intelligence Based Primary Care

    Artificial Intelligence and Human Cognition in General Practice and Family Medicine
    • 1 Edición
    • Anthony C. Chang + 5 más
    • Inglés
    Artificial Intelligence Based Primary Care: Artificial Intelligence and Human Cognition in General Practice and Family Medicine provides a comprehensive look into the integration of artificial intelligence within primary care. This book aims to bridge the gap between data scientists and primary care clinicians by presenting potential AI applications, implementation challenges, and real-world clinical scenarios in an accessible manner. Comprised of 5 sections and 20 chapters, it offers both theoretical insights and practical guidance for family medicine practitioners.Additi... the book includes a chapter dedicated to a day in the life of a General Practitioner, showcasing the practical impact of AI. It also features an extra compendium listing the Top 100 articles and best books on Artificial Intelligence. This resource is invaluable for academics, researchers, and clinicians eager to expand their knowledge in this emerging field.

  • A Comprehensive Guide to Dorsal Root Ganglion Stimulation for Pain Management

    • 1 Edición
    • Scott G. Pritzlaff + 4 más
    • Inglés
    A Comprehensive Guide to Dorsal Root Ganglion Stimulation for Pain Management explores the theoretical foundations, clinical applications, and technical nuances of DRG stimulation, providing a robust framework for understanding and implementing this advanced pain management technique. The book consolidates current best practices, novel technical considerations, and emerging research into a single, authoritative volume. Main themes include the anatomical and physiological basis of DRG stimulation, clinical indications, patient selection, surgical techniques, device programming, and long-term patient outcomes. By integrating insights from leading experts in the field, the book provides a comprehensive and practical guide for clinicians, researchers, and students. Distinct from existing titles that merely touch upon the subject, this book offers a detailed and specialized focus on DRG stimulation, including up-to-date evidence, clinical guidelines, and case studies. The book also features pedagogical elements such as learning objectives, review questions, and case studies to enhance understanding and application.

  • Molecular and Cellular Biology Approaches and Applications in Modern Drug Discovery

    • 1 Edición
    • Mithun Rudrapal + 1 más
    • Inglés
    Molecular and Cellular Biology Approaches and Applications in Modern Drug Discovery is an essential guide that bridges the latest advances in molecular and cellular biology to revolutionize drug discovery. The book explores a wide range of tools and techniques and their applications in drug discovery, including genetic engineering, gene therapy, regenerative medicine, developmental biology, molecular diagnostics, biomarkers, RNA therapeutics, molecular immunology, and vaccine development. The book also considers multi-omics approaches, biophysical methods, epigenetics and epigenomics, biomedical engineering, nanotechnology, artificial intelligence, bioinformatics, structural and computational approaches, and more.This comprehensive volume covers critical domains such as transcriptomics, proteomics, genomics, genetics, and cell signaling pathways, providing an in-depth understanding of their pivotal roles in drug development. It is an invaluable reference for researchers and advanced students working in these areas across molecular biology, biochemistry, pharmacology, biotechnology, and related fields.

  • Multiple Faces of Takotsubo Syndrome

    Clinical Presentations, Mechanisms and Advanced Diagnostic Insights
    • 1 Edición
    • Luca Saba + 1 más
    • Inglés
    Multiple Faces of Takotsubo Syndrome: Clinical Presentations, Mechanisms and Advanced Diagnostic Insights offers a thorough review of Takotsubo syndrome and the role of advanced imaging techniques in improving diagnosis, monitoring, and management of this complex cardiac condition. The book begins with an introduction to Takotsubo syndrome, covering its historical background, prevalence, and key clinical characteristics. Subsequent chapters delve into epidemiology, risk factors, and psychological aspects, including the impact of COVID-19 and other viral infections. Then, clinical manifestations, management, prevention, and treatments are thoroughly discussed, along with complications and prognosis. The basic science section explores the pathophysiological mechanisms, the heart-brain axis, and multi-organ involvement.A significant focus throughout is placed on invasive and non-invasive imaging modalities, including angiography, echocardiography, cardiac MRI, computed tomography, and nuclear imaging. Future directions highlight emerging biomarkers and imaging techniques for personalized medicine, and real-world case studies provide practical insights for clinicians. The book offers invaluable benefits to scientists, researchers, and clinicians alike.

  • Pioneering Precision in Cancer Treatment through 3D Bioprinting

    • 1 Edición
    • Anand Krishnan + 3 más
    • Inglés
    Pioneering Precision in Cancer Treatment through 3D Bioprinting explores the transformative impact of 3D bioprinting on cancer therapy. This groundbreaking book examines innovative techniques revolutionizing cancer care, from creating patient-specific tumor models to accelerating drug discovery and enabling personalized treatments. It offers a comprehensive look at how 3D bioprinting is reshaping oncology. The book details the creation of intricate tumor models that mimic the in vivo environment, enabling precise drug testing and individualized treatment plans. It highlights 3D bioprinting's role in drug screening, tumor modeling, and creating implantable scaffolds for cancer treatment.By manipulating cell arrangements and microenvironments, 3D bioprinting produces accurate cancer models. For the academic audience, this book blends bioengineering, medical insights, and real-world applications. It provides valuable case studies and developments in 3D cancer model creation, enhancing the understanding of oncogenesis, tumor progression, and therapy responses.

  • Advances in Microbial Physiology

    • 1 Edición
    • Volumen 89
    • Inglés
    Advances in Microbial Physiology, Volume 89 explores the latest research and developments in microbial physiology, providing a comprehensive overview on how microorganisms function, adapt, and interact with their environments. This volume brings together leading experts to discuss fundamental processes such as metabolism, growth, gene regulation, signal transduction, stress responses, and cellular differentiation in bacteria, archaea, and fungi. Chapters cover Steroids as Antibacterials, From Feeding Cell to Fruiting Body: Multidrug Transport in the Life cycle of Dictyostelium discoideum, Evolution of xenobiotic catabolism, Glycyl-radical enzymes, How anaerobes cope with oxygen, and Extracellular Electron Transfer: From Early Life to Modern Biogeochemistry and Applications.

  • Trauma During Pregnancy

    • 1 Edición
    • Jorge Hidalgo + 2 más
    • Inglés
    Trauma During Pregnancy, a volume in the Critical Care Obstetrics series, is a novel reference to educate physicians, nurses, and all allied healthcare personnel caring for pregnant women experiencing trauma. The book's authors offer best practices and evidence-based material explicitly focused on the most common complications in pregnant patients that may occur to improve patient care. It not only covers critical care investigation from medical-surgical complications that any patient can present, but also how to prepare and anticipate complications in the critical care unit.

  • Ion Channels in Cellular Pathophysiology Part B

    • 1 Edición
    • Volumen 98
    • Inglés
    Ion Channels in Cellular Pathophysiology Part B, Volume 98 covers a variety of timely topics, including Nerve electrophysiological alterations in experimental diabetic neuropathy, Possible therapeutic effects of essential oils on Na channels in experimental diabetic neuropathy, Breast cancer and voltage gated ion channels, Cardioprotective effect of natural products on doxorubicin-induced acute cardiotoxicity and cardiac ischemia-reperfusion injury,and Modulation of ion channels by Group I metabotropic glutamate receptors.

  • Precision Oncology in Liver Cancer

    Genomics, Infection, and the Exposome in African and Global Contexts
    • 1 Edición
    • Zodwa Dlamini
    • Inglés
    Precision Oncology in Liver Cancer: Genomics, Infection, and the Exposome in African and Global Contexts explores liver cancer through the lens of precision medicine, integrating molecular profiling, environmental exposures, and targeted therapies. The book presents a multidisciplinary approach, covering infectious drivers like HBV/HCV, environmental carcinogens such as aflatoxins, and emerging tools including genomics, AI, and liquid biopsies. It emphasizes African-specific challenges and innovations, with case studies and comparative global insights. This volume equips researchers, clinicians, and policymakers with evidence-based strategies to address liver cancer disparities, offering a forward-looking framework for equitable cancer care and research in Africa and globally.

  • Advances in Applied Mechanics

    • 1 Edición
    • Volumen 66
    • Inglés
    Advances in Applied Mechanics series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Combinatorial Biotechnology

    Methods for Synthesis of Peptide, Oligonucleotide and Oligosaccharide Libraries and Applications
    • 1 Edición
    • Preeti Srivastava
    • Inglés
    Combinatorial Biotechnology: Methods for Synthesis of Peptide, Oligonucleotide and Oligosaccharide Libraries and Applications covers methods used for synthesizing peptide, oligonucleotide, and oligosaccharide libraries. It presents the concepts of combinatorial biotechnology, detailing both solid phase and solution phase synthesis techniques, including modern biological methods such as in vitro and in vivo display libraries. Key topics include solid phase synthesis, parallel peptide synthesis, encoding technologies, deconvolution methods, and chemical and biological ligations. With chapters covering the chemical and biological synthesis of recombinant peptides and proteins, as well as the genetic reprogramming of the genetic code, this book offers a rich source of practical guidance.The inclusion of advanced methods and illustrative examples makes it a unique and essential reference in the field. This book is an essential resource for undergraduate and postgraduate students in biochemical engineering, biotechnology, and biosciences, as well as industry professionals in R&D divisions. It equips readers with the latest techniques and applications in combinatorial biotechnology, addressing current challenges and advancing their research and development efforts.

  • Pediatric Substance Exposure

    • 1 Edición
    • Ju Lee Oei
    • Inglés
    Pediatric Substance Exposure is a crucial resource for medical practitioners focusing on the long-term management of children exposed to addictive substances during pregnancy. It provides guidance on supporting families affected by substance abuse, starting with a comprehensive overview of epidemiology and global policy. The book examines various substances and their impact on children, discussing fetal management, infant and child care, and addressing family needs as the child grows. Beyond the basics, the book reviews social aspects, future research, and policy needs. Clinicians and researchers will find it invaluable for evidence-based decision-making and optimal treatment strategies.

  • Emerging Technologies in Bioengineering for Oncology

    Fundamentals, Research, and Future Prospects
    • 1 Edición
    • Saikat Das + 2 más
    • Inglés
    Emerging Technologies in Bioengineering for Oncology: Fundamentals, Research, and Future Prospects explores the integration of engineering, biology, and medicine to tackle challenges in developing innovative tools for cancer diagnosis and treatment. This comprehensive resource addresses the evolving landscape of bioengineering in oncology, highlighting the intersection of various disciplines to drive advancements in diagnostic and therapeutic approaches. The book explores a range of cutting-edge technologies such as lab-on-chip devices, wearable biosensors, 3D bioprinting, and targeted nanomedicine, offering promising avenues for enhanced diagnostic precision, treatment effectiveness, and personalized healthcare.Geared towards medical students and professionals, the book provides detailed insights into the latest developments, practical applications, and future research directions in the field. By offering a deep dive into the realm of bioengineering for oncology, it serves as a valuable asset for those seeking to advance cancer care through interdisciplinary collaboration and innovation.

  • Enzyme Technology for Environmental Sustainability, Waste to Wealth, and Circular Economy

    • 1 Edición
    • Shrikaant Kulkarni
    • Inglés
    Enzyme Technology for Environmental Sustainability, Waste to Wealth, and Circular Economy offers a comprehensive look at how enzyme technology can drive environmental progress within the framework of biochemistry. Beginning with foundational concepts, the book introduces readers to the science behind enzymes and their practical applications. Each chapter builds upon these basics, illustrating how enzymes catalyze vital processes that contribute to sustainability and the transformation of waste into valuable resources. Through focused case studies and clear explanations, the book demonstrates the potential of enzyme-driven solutions to address urgent environmental challenges and promote a circular economy.Beyond its central focus, the book stands out by delivering pragmatic examples that remain within biochemical boundaries, avoiding broader discussions in public health or environmental science. It is designed as a valuable reference for biochemists, researchers, and industry professionals, emphasizing collaboration and innovation rooted in biochemical expertise. Readers will gain an enriched understanding of enzyme technology’s role in sustainable industrial practices and the future of environmentally responsible solutions.

  • Lifestyle Epigenomics

    • 1 Edición
    • Ana B Crujeiras
    • Inglés
    Lifestyle Epigenomics, a new volume in the Translational Epigenetics series, comprehensively details the interplay between lifestyle factors and epigenetic modifications associated with the onset of noncommunicable diseases and aging, shedding light on potential preventive and therapeutic strategies for disease from an epigenomics perspective. Here, more than 35 international experts in the field consider how lifestyle choices or habits can condition or prevent disease, along with tools for new research, from bioinformatics methodology to non-invasive sampling.Early, foundational chapters are followed by all-inclusive sections on epigenetic machinery in health and disease; dietary factors and epigenetics; adiposity and physical activity and epigenetics; psychological stress, social environment, toxins and contaminants exposure effects on epigenetics; and transgenerational and childhood epigenetics. To support understanding, each chapter includes a summary and key points lists, terms and definition, as well as research case studies outlining core components of recent studies, detailing their conditions, research techniques involved, and outcomes.

  • Carrier-Free Enzyme Immobilization

    Fundamentals and Innovations in Biocatalysis
    • 1 Edición
    • Mehdi Mohammadi + 1 más
    • Inglés
    Carrier-Free Enzyme Immobilization: Fundamentals and Innovations in Biocatalysis explores innovative techniques for immobilizing enzymes without the use of inert carriers, highlighting their advantages, applications, and integration into modern biocatalytic processes. The book begins by introducing the concept of enzyme immobilization and the transition from traditional carrier-bound methods to innovative carrier-free techniques. It discusses the fundamental principles behind carrier-free immobilization, including the types of cross-linkers used and the advantages in enhancing enzyme stability and activity. The book also covers various methods for the structural characterization of carrier-free immobilized enzymes.With a strong focus on practical implementation, it examines the applications of carrier-free immobilized enzymes across different industries, highlighting the pros and cons of the method. It explores novel approaches for producing carrier-free immobilized biocatalysts and provides a comparative analysis of carrier-free versus traditional carrier-bound immobilization techniques. The book also addresses the challenges associated with implementing carrier-free immobilization in industrial processes and proposes potential solutions to overcome these obstacles. It is an essential resource for biochemists, chemical engineers, and researchers in biotechnology who are involved in enzyme research and development.

  • Protein Kinase Inhibitors

    The Promise of Natural Products in Cancer Therapeutics
    • 1 Edición
    • Md. Imtaiyaz Hassan + 1 más
    • Inglés
    Protein Kinase Inhibitors: The Promise of Natural Products in Cancer Therapeutics explores a novel therapeutic avenue for cancer treatment through nutraceutical-based kinase inhibitors. The book covers their historical background, outlook, mechanistic pathways, and clinical aspects, highlighting their relevance in cancer therapy. It also examines the potential of polyphenolic derivatives and other natural compounds in inhibiting key kinases involved in major cancer signaling pathways, focusing on their application in clinical trials and marketed drugs. Sections explore the implications of polyphenols in cancer management, novel sources of breast cancer inhibitors, the role of natural products in lymphoma therapy, and the multitarget potential of phytochemicals. Each chapter is designed to provide a thorough understanding of how natural products can be harnessed to develop innovative cancer therapeutics. It will serve as a valuable resource for academics, scientists, young researchers, students, and pharmacists working or interested in kinase biology and cancer therapeutics with its unique perspective on using nature's own arsenal to combat cancer.

  • Radiation Biology

    Molecular Foundations and Clinical Applications
    • 1 Edición
    • Barry S. Rosenstein + 1 más
    • Inglés
    Radiation Biology: Molecular Foundations and Clinical Applications is a comprehensive exploration of the effects of radiation on living organisms, delving into the molecular mechanisms underlying cellular responses. This book examines critical topics such as radiation-induced DNA damage, repair processes, and molecular signaling pathways. It provides a detailed look at how cells respond to radiation, addressing cell cycle control, apoptosis, and the effects of radiation on immune system functionality. As a resource for researchers, it bridges the gap between molecular biology and clinical oncology, offering insights into radiation's role in both therapeutic contexts and its broader impact on human biology.In addition to its focus on molecular responses, the book covers topics like tumor microenvironment and metabolism, the role of epigenetics in radiation biology, and the hallmarks of cancer relevant to radiation therapy. It also provides discussions on chemotherapeutic agents, radiation carcinogenesis, and the complex interplay between radiation and cancer biology. The later sections extend the scope to tissue, organ, and systemic effects of radiation, making it an invaluable reference for professionals in molecular biology, oncology, and related fields striving to push the boundaries of radiation research.

  • Flavoproteins and Flavoenzymes

    • 1 Edición
    • Volumen 738
    • Inglés
    Flavoproteins and Flavoenzymes, Volume 738 in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Kirisu2 and KiPaD: global analysis of rapid flavoprotein redox kinetics from stopped-flow multi, ilagros Mendina, A Generic First Approach to Dissecting Flavoenzyme Catalytic Cycles, Removing Covalent Constraints of Protein Loops and Lids by a Split-Gene Strategy, Designing Oxygen Reaction Sites in Flavoprotein Dehydrogenases, Converting Noncovalent Flavoproteins into Covalently Flavinylated Proteins, Complexities of Riboflavin Biosynthesis, Reactions of Riboflavin Catabolism, and much more.Additional sections cover Ferredoxin-dependent thioredoxin reductase, Thermophilic Methylenetetrahydrof... Reductases, Ion-Pumping NADH:Quinone Oxidoreductase, Loading E. coli Dihydroorotate Dehydrogenase with Coenzyme Q, and Single-Component Halogenases.

  • Fundamentals of Absorption Spectroscopy

    • 1 Edición
    • Imtaiyaz Hassan
    • Inglés
    Fundamentals of Absorption Spectroscopy offers a clear and comprehensive introduction to the principles, instrumentation, and applications of absorption spectroscopy across UV-Visible, IR, and other spectral regions. Designed for students, researchers, and industry professionals, this book bridges theory and practice with practical illustrations and real-world case studies, providing a solid foundation in both fundamental concepts and contemporary applications in chemistry, biology, medicine, environmental monitoring, and materials science. It fills the gap between overly advanced and overly simplified texts by combining fundamental theory with practical insights, particularly from biological perspectives. This book addresses the need for an updated, student-friendly, and application-oriented resource in absorption spectroscopy. Readers will benefit from structured guidance that connects theoretical principles with experimental data, explains instrumentation and its limitations, and demonstrates applications across diverse fields such as pharmaceuticals, environmental analysis, and biomolecular sciences. The inclusion of case studies and recent advances in spectroscopic technology ensures relevance for both academic study and professional practice.

  • Non-Invasive Prenatal Screening of Rare Fetal Genetic Diseases

    • 1 Edición
    • Riyaz Ahmad Rather
    • Inglés
    Non-Invasive Prenatal Screening of Rare Fetal Genetic Diseases offers a comprehensive exploration of the latest advancements in non-invasive prenatal screening (NIPS) technologies and their application in detecting rare fetal genetic disorders. It provides a detailed overview of current methods in NIPS technology, the application of NIPS in detecting rare genetic disorders, and ethical considerations. Sections cover advanced genomic methods such as Next-Generation Sequencing, Single-Nucleotide Polymorphism analysis, and Comparative Genomic Hybridization, highlighting their impact on the accuracy and scope of NIPS, while also exploring specific genetic disorders, including Trisomy 18, Trisomy 13, Duchenne Muscular Dystrophy, Angelman Syndrome, Turner Syndrome, and Cri du Chat Syndrome.Researchers will find this to be a valuable resource for understanding and applying NIPS protocols in their work, while clinicians will benefit from practical insights on appropriate screening methods, interpreting NIPS results, and counseling expectant parents. This book is an essential resource for researchers in obstetrics and gynecology, genetic counselors, and professionals in the biotechnology and pharmaceutical industries. It equips readers with the knowledge and tools needed to advance their work and improve prenatal care practices.

  • Melanin-Concentrating Hormone

    From Metabolism to Sleep Disorders
    • 1 Edición
    • Jackson C. Bittencourt + 1 más
    • Inglés
    Melanin-Concentratin... Hormone: From Metabolism to Sleep Disorders, the latest volume in the Molecular Mediators in Health and Disease series, offers a comprehensive understanding of this multifunctional peptide. The book covers a wide range of topics, including molecular biology of MCH, MCH in organ function, pharmacology, and MCH in disease. Recent developments in MCH imaging and pharmacological modulation are explored, along with the impact of MCH in psychiatric and neurodegenerative disorders and its role in the neuroimmunological modulation of vitiligo. Additionally, MCH is considered in the context of reproductive behavior, sleep, cognition, memory, and peripheral function.The book also explores MCH across various species such as humans, reptiles, non-primate mammals and teleosts. This is an ideal reference for researchers working with MCH across the fields of cell biology, molecular biology, pharmacology, neuroscience, endocrinology, and beyond.

  • Advances in Medical Imaging

    From Behavioral Analysis to Disease Prevention and Rehabilitation
    • 1 Edición
    • Dilber Uzun Ozsahin + 4 más
    • Inglés
    Advances in Medical Imaging: From Behavioral Analysis to Disease Prevention and Rehabilitation presents a comprehensive exploration of the rapidly evolving field of medical imaging at the crossroads of clinical science, behavioral research, and public health. This book addresses the growing need to understand how advanced imaging technologies—such as MRI, PET, and ultrasound—are transforming healthcare beyond traditional diagnosis. By capturing structural, functional, metabolic, and molecular processes, these innovations provide new insights into brain function, lifestyle impacts, chronic disease, and rehabilitation, supporting the shift toward personalized and preventive medicine.The book is organized into five thematic sections covering a wide range of topics. Early chapters focus on the integration of neuroimaging with behavioral science, highlighting brain–behavior relationships through cutting-edge imaging modalities and cognitive software. Subsequent sections examine the effects of sedentary lifestyles on brain health, vascular function assessed by ultrasound, and musculoskeletal aging through imaging biomarkers. Additional chapters explore chronic disease management, yoga and cognitive well-being, stroke recovery, traumatic brain injury rehabilitation, and the expanding role of imaging in oncology and systemic diseases. Throughout, the book emphasizes the use of artificial intelligence, radiomics, and multimodal imaging to enhance precision medicine and population health research.Advances in Medical Imaging: From Behavioral Analysis to Disease Prevention and Rehabilitation offers valuable insights for researchers, clinicians, and healthcare professionals interested in the applications of medical imaging across multiple disciplines. It highlights imaging’s critical role in advancing personalized care, supporting preventive strategies, and fostering innovation in modern healthcare.

  • Artificial Intelligence in Livestock Omics

    Applications, Challenges, and Future Perspectives
    • 1 Edición
    • Navid Ghavi Hossein-Zadeh
    • Inglés
    Artificial Intelligence in Livestock Omics: Applications, Challenges, and Future Perspectives delves into the cutting-edge intersection of AI and livestock science, exploring how advanced algorithms are transforming the analysis and application of omics data in livestock production. This book addresses the convergence of AI and biotechnology, highlighting how these fields are not only transforming livestock farming but also contributing to broader goals within personalized medicine, genetic improvement, and the development of resilient animal breeds. Sections provide readers with practical insights, real-world case studies, and a forward-looking perspective on the future of AI-driven livestock management.The integration of AI with omics technologies can also aid in global efforts to improve food security, animal welfare, and sustainable agricultural practices. Whether a researcher, industry professional, or policymaker, this book offers valuable tools and strategies to enhance precision farming, improve animal health, and drive sustainable agriculture in the digital age.

  • The Hormonal Treatment of Endometriosis and Adenomyosis

    A Comprehensive Review of the Role of Hormonal Treatments in the Management of Pain and Infertility in Patients with Endometriosis and Adenomyosis
    • 1 Edición
    • Antoine Naem + 1 más
    • Inglés
    The Hormonal Treatment of Endometriosis and Adenomyosis: A Comprehensive Review of the Role of Hormonal Treatments in the Management of Pain and Infertility in Patients with Endometriosis and Adenomyosis is a comprehensive and practical reference on the effects of various hormonal treatments on endometriosis and adenomyosis lesions. The book summarizes the latest evidence regarding the safety and efficacy of these treatments in managing pain associated with these conditions. Additionally, the book explores the evidence-based benefits of hormonal therapies in improving fertility chances for patients, both through natural conception and assisted reproductive technologies.The book helps readers grasp the generalizability of current research findings and identifies existing research gaps, shedding light on new perspectives for future investigation. Through this comprehensive approach, the book serves as an invaluable resource for healthcare professionals, researchers, and patients alike.

  • Pediatric Pulmonology

    A Global Handbook for Clinical Care Providers
    • 1 Edición
    • Allen J. Dozor
    • Inglés
    Pediatric Pulmonology: A Global Handbook for Clinical Care Providers provides an in-depth exploration of pediatric respiratory diseases, offering a detailed examination of various conditions, diagnostic techniques, and treatment protocols. The book covers a wide range of topics, from the assessment of children with respiratory diseases to specific conditions such as asthma, cystic fibrosis, and bronchopulmonary dysplasia. Each chapter is contributed to by leading experts in the field, ensuring that the content is both authoritative and up-to-date. These crucial, practical skills are essential when a pediatric patient's first point-of-care is not a respiratory specialist.This is especially true of medical treatment in resource-poor areas. The book includes "how to guides" on vital procedures such as spirometry, chest imaging, and the management of respiratory emergencies. It also addresses respiratory diseases in newborns, the impact of environmental factors on children's respiratory health, and the unique challenges faced by children with neurologic and neuromuscular diseases. This comprehensive approach ensures that non-specialists gain a holistic understanding of pediatric respiratory diseases and their management.

  • Generative Artificial Intelligence for Neuroimaging

    Methods and Applications
    • 1 Edición
    • Deepika Koundal + 1 más
    • Inglés
    Generative Artificial Intelligence in Neuroimaging: Methods and Applications offers a clear and practical guide for biomedical engineers and data scientists interested in using generative AI to improve neuroimaging techniques. The book explains key generative models, such as GANs, VAEs, and diffusion models, and shows how these methods can enhance data analysis, improve image quality, and support personalized medicine. It includes real-world examples that demonstrate the successful use of AI in diagnosing diseases and developing brain-computer interfaces. The book also discusses important ethical considerations and best practices for using AI responsibly in healthcare.Finally, the book addresses technical challenges and highlights future research opportunities in the field of AI and biomedical engineering. Whether you are an experienced professional or a new researcher, this book provides the knowledge and tools needed to advance neuroimaging and contribute to better patient care.

  • Signal Processing-Driven AI for Healthcare

    • 1 Edición
    • Ildar Rakhmatulin + 1 más
    • Inglés
    Signal Processing-Driven AI for Healthcare examines how AI techniques can be applied across four major biosignals—EEG, EMG, EOG, and ECG—to derive clinically meaningful insights. As biomedical data becomes increasingly multimodal, there is a rising need for integrated methodologies that unite these signals within robust, explainable AI pipelines suitable for healthcare environments. This book provides a unified framework that spans data acquisition, preprocessing, feature extraction, modeling, evaluation, and deployment, with an emphasis on reproducibility, practical Python-based implementations, and real-world translation to clinical workflows.

  • Technological Applications of Fungal Enzymes in Biorefinery and Bioproducts Development

    Volume 2
    • 1 Edición
    • Manikant Tripathi + 1 más
    • Inglés
    Technological Applications of Fungal Enzymes in Biorefinery and Bioproducts Development provides a thorough understanding of technological advances and utilization of fungal enzymes for the development of useful products through using advanced microbial biotechnological techniques. This is the second of two volumes that provide a comprehensive overview of the utilization of fungal enzymes for biorefinery and bioproduct development. Volume 2 discusses basic and technological interventions in fungal enzyme applications exploring biotechnological strategies and how they can address challenges and solutions in the processes involved in fungal enzyme applications. The book also offers practical examples and case studies of technology advances in fungal enzyme-mediated development of biofuels and bioproducts. In combination with Volume 1, this book offers a holistic view of the potential and challenges of engineered fungal enzymes for researchers, scientists, and industry professionals seeking to deepen their knowledge of fungal enzymes and their role in biochemical advances.

  • Epidemic Modeling

    Principles, Algorithms, and Applications
    • 1 Edición
    • Teddy Lazebnik
    • Inglés
    Epidemic Modeling: Principles, Algorithms, and Applications is a comprehensive introduction and practical guide to building, understanding, and applying epidemiological models in real-world contexts. Bridging theory and practice, the book walks readers through the full modelling pipeline from the biological, social, and political drivers of disease spread to classical compartmental models such as SIR, and onward to modern computational techniques including agent-based simulation, machine learning, and optimization under uncertainty. Each chapter builds progressively, pairing clear conceptual explanations with hands-on code, real data examples, and step-by-step methods that readers can adapt to new challenges. Drawing on extensive academic and industry experience, the text emphasizes how modelling decisions are made in practice addressing real-world complications such as incomplete data, reporting delays, and measurement error. Designed as both a learning resource and long-term reference, the book equips readers to move beyond running existing models to designing, evaluating, and communicating their own. It also fosters a shared language across disciplines, helping technical and non-technical audiences engage meaningfully with modelling insights. Timely and practical, this book empowers the next generation of modelers and decision-makers to respond effectively to an increasingly complex epidemic landscape.

  • Artificial Intelligence in Brain Disorders

    Innovations in Diagnosis and Treatment
    • 1 Edición
    • Pranav Kumar Prabhakar + 3 más
    • Inglés
    Artificial Intelligence in Brain Disorders: Innovations in Diagnosis and Treatment focuses on the utilization of AI and machine learning to enhance current practices in the diagnosis and treatment of neurological disorders. Each chapter provides in-depth exploration of specific areas where AI can improve existing methodologies, offering practical guidance, case studies, and research findings that can be directly applied in the field. It explains the application of AI in diagnosing and treating major neurological illnesses and showcases the potential of AI in predicting diseases such as epilepsy and neurodegenerative disorders.As such, this book offers a detailed overview of AI and machine learning techniques relevant to neurological research.

  • Advances in Clinical Chemistry

    • 1 Edición
    • Volumen 134
    • Inglés
    Advances in Clinical Chemistry, Volume 134 in this ongoing series, examines physiologic and pathophysiologic biochemistry and impacts on Clinical Chemistry testing and design. Sections cover Molecular mechanisms of disease and advances in the development of improved diagnostic and predictive biomarkers. Specific chapters in this new release include Biomarkers in Heart Failure, RNA biomarkers in antidoping, Cardiovascular disease and miRNA, Chronic low-grade inflammation in vegetarians and vegans: biomarker evidence and methodological considerations, Advances in microfluidic extracellular vesicle technology, and Biomarkers for Assessing Magnesium Status.As these evolving technologies and analytic strategies have become increasing relevant given the healthcare and socioeconomic impact worldwide, this book provides an essential reference.

  • Erythropoiesis/Hematopoiesis

    • 1 Edición
    • Volumen 170
    • Inglés
    Erythropoiesis/Hemat... Volume 170 provides a comprehensive overview of erythropoiesis and hematopoiesis—the processes by which blood cells are formed, developed, and maintained in the body. The book covers the molecular, cellular, and physiological mechanisms that regulate the formation of red blood cells (erythropoiesis) and all other blood cell lineages (hematopoiesis), including stem cell biology, signaling pathways, and genetic regulation. Timely chapters in this new release include Ribosomal RNA transcription in normal and leukemic hematopoiesis, Regulation of erythroid development by iron metabolism, Mediator at the Helm: Coordinating Transcription and Biomolecular Condensates in Hematopoiesis, and much more.Additional chapters explore Cell fate decision and lineage specification mechanisms in hematopoiesis, Hijacking the Host: Red Blood Cell Remodeling and Extracellular Vesicle Release During Babesia Infection, How advances in chromosome conformation capture methods are reshaping our understanding of gene regulation in haematopoiesis, Post-transcriptional regulation in erythropoiesis, Erythropoiesis resolved through spatial omics, and Transcription elongation mechanisms that control gene expression in erythropoiesis.

  • Advancing Body Fluid Diagnostics with Flow Cytometry

    A Comprehensive Guide to Effusions and CSF
    • 1 Edición
    • Namrata P. Awasthi
    • Inglés
    Advancements in Pathological Diagnosis: Harnessing Flow Cytometry for Detection of Malignant Epithelial Cells in Body Fluids is an invaluable resource for anyone involved in cytology and pathology, especially those interested in leveraging flow cytometry for diagnostic purposes. The book offers a comprehensive understanding of how flow cytometry can enhance the detection of malignant epithelial cells in body fluids, providing both theoretical knowledge and practical guidance. Flow cytometry's ability to rapidly analyze individual cells based on their properties is truly remarkable, and its application in detecting early-stage malignancies and screening large numbers of cells efficiently is invaluable. The book bridges the gap between traditional cytological diagnostics and the evolving landscape of technological advancements in pathology. Moreover, the inclusion of detailed chapters on flow cytometry and its applications in cytological diagnostics for effusion samples suggests that the book caters to both beginners in the field and seasoned professionals seeking to expand their knowledge base. The endorsement from medical professionals such as medical oncologists, surgical oncologists, gastroenterologists, and general surgeons further underscores the relevance and practicality of the book in enhancing diagnostics and patient care across various medical specialties. "Advancements in Pathological Diagnosis" is a timely and essential contribution to the field of cytology and pathology, offering a comprehensive guide to leveraging flow cytometry for improved diagnostics in the context of malignant epithelial cells in body fluids.

  • Cell Death Part E

    • 1 Edición
    • Volumen 210
    • Inglés
    Cell Death: Part E, Volume 210 presents the latest advances and comprehensive reviews in the rapidly evolving field of cell death. This volume explores the molecular mechanisms, regulatory pathways, and biological consequences of various forms of cell death—including apoptosis, necrosis, autophagy, and other non-canonical processes. Chapters in this new release include Flow cytometry analysis of mitochondrial apoptotic priming with BH3 profiling on senescent cells, Methods to study PIDDOsome and caspase 2 signaling, Isolation, characterization, and experimental applications of apoptotic bodies in vitro, Lipid ROS Measurement by Spectral Flow Cytometry based on the ratiometric dye BODIPYTM C11 581/591, and much more.Additional chapters cover CRISPR-Cas9 Screen to Identify Genes Regulating Cell Death, Flow cytometry-assisted discrimination of early apoptotic, late apoptotic and primary necrotic morphological markers in Saccharomyces cerevisiae, Cytofluorometric analysis of cell death in primary human neutrophils, Real-time tracking of cell death in human intestinal organoids: a quantitative imaging approach, and more.

  • Fundamentals and Functional Advancements of Fungal Enzymes in Biorefinery and Bioproducts Development

    Volume 1
    • 1 Edición
    • Manikant Tripathi + 1 más
    • Inglés
    Fundamental and Functional Advancements of Fungal Enzymes in Biorefinery and Bioproducts Development offers highlights the fundamental aspects of fungal enzymes which include their structure, function, chemical composition, and their functional importance for biorefinery and bioproducts development. This is the first of two volumes that provides a comprehensive overview of the utilization of fungal enzymes for biorefinery and bioproduct development. Volume 1 introduces various types of fungal enzymes and offers a better understanding of the basic science of fungal enzymes, their structure, their fundamental functions and limitations in biochemical development. This book also explores the processes involved in improving the enhanced production, efficiency, and efficacy of fungal enzymes for application. It also examines biofuel and bioproducts production using fungal enzymes. In combination with Volume 2, this book offers a holistic view of the potential and challenges of engineered fungal enzymes for researchers, scientists, and industry professionals seeking to deepen their knowledge of fungal enzymes and their role in biochemical advances.

  • Humanizing Artificial Touch

    Skin, Sensing, and Structures
    • 1 Edición
    • John-John Cabibihan
    • Inglés
    Humanizing Artificial Touch: Skin, Sensing, and Structures contains recent advances in artificial skin modelling and robotic tactile sensing technologies, integrating these in the structure of an artificial hand mimicking its important features. This book will give special treatment to the relationship between the artificial skin material and embedded tactile sensors, describing how artificial skin and embedded sensors can be designed and constructed using 3D printing technologies with case examples on how these were created for amputees achieve a more a natural and rich human-robot tactile interaction.This book is oriented towards students, researchers, and clinical practitioners who are working in the design and construction of artificial hands for prosthetics and social robotics.

  • Chromatin Signaling and Diseases

    • 2 Edición
    • Olivier Binda + 2 más
    • Inglés
    Chromatin Signaling and Diseases, Second Edition, a volume in the Translational Epigenetics series, covers the molecular mechanisms that regulate gene expression, which governs embryonic development, growth, and human pathologies associated with aging, such as cancer. Although human genome sequencing continues to improve, molecular mechanisms regulating gene expression remain largely misunderstood. The impact of gene expression defects associated with malfunctioning chromatin signaling are considered in this update. In addition, this new edition has addresses developments in the field, from phase separation of membrane-less organelles and local segregation of factors to chromatinization of naked foreign DNA and cancer evolution as regulated by chromatin signaling.Chromatin signaling proposes that small protein domains recognize chemical modifications on the genome scaffolding histone proteins, facilitating the nucleation of enzymatic complexes at specific loci that then open up or shut down the access to genetic information, thereby regulating gene expression. The addition and removal of chemical modifications on histones, as well as the proteins that specifically recognize these are also considered.

  • On Human Nature

    Biology, Psychology, Ethics, Politics, and Religion
    • 2 Edición
    • Michel Tibayrenc
    • Inglés
    On Human Nature: Biology, Psychology, Ethics, Politics, and Religion covers the present state of knowledge on human biological and cultural diversity and its adaptative significance through an extensive selection of representative chapters. Edited by renowned expert Michel Tibayrenc, this second edition features updates to all major sections of the first edition and brings novel chapters covering critical advancements in human biology, psychology, behavior, ethics, and culture. It is accessible not only to specialists, but also to students, professors, industry professionals, and the educated public. Glossaries of specialized terms and general public references help nonspecialists understand complex notions, with contributions avoiding technical jargon.The book brings together specialists from various fields, including geneticists, evolutionists, physicians, ethologists, psychoanalysts, anthropologists, sociologists, theologians, historians, linguists, and philosophers. A globally diverse and interdisciplinary team of experts has been carefully selected to cover the breadth of topics enclosed.

  • Probiotics

    A Comprehensive Exploration of Health Benefits and Innovation
    • 1 Edición
    • Ranbir Chander Sobti
    • Inglés
    Probiotics: A Comprehensive Exploration of Health Benefits and Innovation explores the potential of probiotics and their fundamental role in human health and disease prevention. The book offers a thorough understanding of how beneficial microorganisms can enhance overall well-being and potentially transform treatment approaches across multiple disciplines. The first section lays the groundwork by exploring the fundamentals of probiotics, prebiotics, and their interactions with the human microbiome, while the second section examines the role of probiotics in disease prevention and management, highlighting their impact on conditions such as diabetes, obesity, and mental health.The third section discusses specialized applications of probiotics in women's health, pediatrics, and geriatrics, as well as their innovative uses in skin care and nutrition. Finally, the fourth section investigates the future potential of probiotics in synthetic biology, in personalized health, and in combatting antibiotic resistance. With contributions from a diverse group of experts in the field, the book serves as an interdisciplinary resource for researchers, clinicians, and industry professionals eager to explore the therapeutic potential and benefits of probiotics.

Temas relacionados