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Libros en Ciencias de la Vida

  • RNA-binding Proteins Part C

    • 1 Edición
    • Volumen 745
    • Inglés
  • Practical Guide to Diagnosing and Treating Ocular Tumors

    • 1 Edición
    • Maura Di Nicola + 1 más
    • Inglés
    Practical Guide to Diagnosing and Treating Ocular Tumors provides practical guidance on the diagnosis and management of ocular tumors. This comprehensive guide highlights the strengths, limitations, and applications of all imaging modalities in ocular oncology. It not only discusses new treatments in ocular oncology (including belzupacap sarotalocan and darovasertib for uveal melanoma, mTOR inhibitors for retinal astrocytic hamartomas in patients with ocular involvement of tuberous sclerosis complex, and belzutifan for retinal hemangioblastomas in patients with Von Hippel Lindau disease), but also offers a comprehensive and practical review of the techniques, complications, and applications of well-established treatments.Ophthalmo... and ocular oncologists will find this to be a practical guide to diagnosing and treating surface and intraocular tumors using a novel approach that will instruct readers on how to utilize and interpret multimodal imaging correctly to diagnose ocular tumors. Readers will gain an understanding of the risks and benefits of different treatment modalities and the most appropriate use scenario in each tumor type.
  • Proteolytic Enzymes and their Inhibitors in Infectious Pathogens

    • 1 Edición
    • Theresa Coetzer
    • Inglés
    Proteolytic enzymes are found in all life forms, where they catalyze peptide bond hydrolysis during essential biological processes. Proteases of various pathogens have also been shown to use endogenous protease inhibitors to regulate the activity of host proteolytic enzymes encountered during infection.Proteolyti... Enzymes and their Inhibitors in Infectious Pathogens brings together key experts to provide a thorough discussion of proteolytic enzymes and their endogenous inhibitors found in parasites, bacteria, and viruses. The book focuses on the respective roles of the different catalytic classes of proteolytic enzymes and their protein-protease inhibitors at the host-infectious organism interface, and how this knowledge may inform drug and vaccine design. Following a foundational overview of proteases and macromolecular inhibitors of pathogenic organisms, authors discuss recent research on distinct classes of proteolytic enzymes in pathogens. Classes include aspartic proteases, cysteine proteases, metalloproteases, serine proteases, and threonine proteases with experts contributing chapters on distinct enzymes and inhibitors. New methods to identify protease substrates and inhibitors are also provided, with step-by-step protocols to advance new research and drive drug discovery.
  • Nanocarriers for Targeted Therapy and Management of Liver Cancer

    • 1 Edición
    • Devesh U. Kapoor + 2 más
    • Inglés
    Nanocarriers for Targeted Therapy and Management of Liver Cancer presents a comprehensive academic overview of nanocarrier‑based strategies for addressing the biological, pharmacological, and translational challenges of liver cancer. The book positions nanomedicine as a critical enabler of targeted, safer, and more effective therapies for hepatocellular carcinoma and related malignancies. The volume systematically covers major nanocarrier platforms alongside emerging approaches such as AI‑assisted design, pharmacokinetic modeling, nanotoxicology, clinical translation, and regulatory considerations. Each chapter integrates foundational concepts with current research, clinical trial insights, and future outlooks to ensure coherence and academic rigor. For researchers and graduate‑level learners, the book provides an authoritative reference that bridges nanocarrier design, liver‑specific biology, and translational feasibility. It supports advanced study, interdisciplinary research, and informed innovation in precision nanomedicine for liver cancer.
  • Advances in Clinical Chemistry

    • 1 Edición
    • Volumen 137
    • Inglés
    Advances in Clinical Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.
  • Transesophageal Echocardiography

    Basic and Advanced Aspects and Clinical Field of Application
    • 1 Edición
    • Antonello D’Andrea
    • Inglés
    Transesophageal Echocardiography: Basic and Advanced Aspects and Clinical Field of Application provides clinicians and echocardiography professionals with a thorough and practical resource covering both the fundamental principles and advanced clinical uses of TEE. It benefits the audience by delivering step-by-step guidance on image acquisition, interpretation of valve and ventricular pathology, and real-world applications in perioperative, emergency, and interventional settings. Richly illustrated and supplemented by instructional videos, the book’s contents include diagnostic techniques, perioperative management, assessment of prosthetic and congenital heart conditions, and specialized topics such as TEE in sports cardiology and critical care—empowering readers to improve patient outcomes and master the latest advancements in cardiovascular imaging.
  • The Transcription Factor NRF2

    Biology, Disease and Translational Opportunities
    • 1 Edición
    • Narendra Kumar Sharma + 1 más
    • Inglés
    The Transcription Factor NRF2: Biology, Disease and Translational Opportunities offers a detailed and authoritative reference on NRF2, a key regulator of cellular defence against oxidative stress. This book thoroughly examines the latest research, from molecular mechanisms to clinical applications, highlighting NRF2’s essential function in cell protection, disease prevention, and its promise as a therapeutic target. The book opens with an introduction to NRF2 and its role in cellular homeostasis before exploring its molecular structure, regulation and signalling mechanisms. Its antioxidant response is then discussed, followed by its impact on inflammation, autophagy, and resistance to environmental and chemical stresses. Later chapters cover NRF2’s role in cancer, neurodegenerative, cardiovascular, autoimmune, and metabolic diseases. Cutting-edge techniques are also provided, including AI-based and systems biology tools. Case studies emphasize translational potential and therapeutic development.The Transcription Factor NRF2: Biology, Disease and Translational Opportunities equips researchers, clinicians, and advanced students with critical knowledge to understand NRF2’s multifaceted functions and therapeutic potential. It serves as an essential guide for advancing research and strategies targeting NRF2 in a diverse array of medical conditions, and is an ideal reference for those working across cell biology, molecular biology, biomedicine and related fields.
  • Precision Care in Gastroesophageal Reflux Disease

    Using Pathophysiology and Clinical Insights towards a Personalized Approach
    • 1 Edición
    • Walter W. Chan + 1 más
    • Inglés
    Precision Care in Gastroesophageal Reflux Disease: Using Pathophysiology and Clinical Insights towards a Personalized Approach addresses the urgent need for personalized approaches in managing GERD. This reference explores the evolving understanding of GERD pathophysiology and the necessity to move beyond generalized treatments toward disease phenotyping and targeted therapy. It emphasizes integrating clinical insights with emerging diagnostic technologies to optimize patient outcomes. The book’s content is organized into sections covering disease phenotypes and pathophysiology, clinical presentation, diagnostic techniques, and management approaches. Chapters include detailed discussions on symptom mechanisms, hypervigilance, diagnostic endoscopy, esophageal function testing, and both medical and surgical treatment options. Contributions from international experts provide evidence-based perspectives on utilizing scoring systems, ancillary tests, and adjunctive therapies to support precision care. Precision Care in Gastroesophageal Reflux Disease equips clinicians, advanced practice providers, and trainees with state-of-the-art knowledge to tailor evaluation and treatment strategies for diverse GERD phenotypes. It is an essential resource for those seeking to apply precision medicine principles in gastroenterology, enhancing diagnostic accuracy and therapeutic effectiveness in clinical practice.
  • Pediatric Culinary Medicine

    Evidence, Opportunities, and Practice
    • 1 Edición
    • Maria R. Mascarenhas + 2 más
    • Inglés
    Pediatric Culinary Medicine: Evidence, Opportunities, and Practice is a groundbreaking resource authored by diverse pediatric leaders, offering a comprehensive exploration of the rapidly evolving field of food as medicine. This book uncovers the history, benefits, and current research landscape, highlighting future opportunities for advancing pediatric health & development through culinary approaches. It provides practical insights into supporting children from diverse cultural and socioeconomic backgrounds, including those managing chronic conditions and those seeking to optimize wellness. Perfect for both newcomers and seasoned practitioners, this book will inspire innovative ways to integrate food into pediatric care. Packed with expert knowledge, this volume covers the evolution of culinary medicine, current research gaps, and practical strategies for real-world application in a pediatric setting. It features detailed chapters on dietary patterns that promote child health, culturally relevant practices, and policy opportunities, along with pathways for training and education, offering essential guidance for translating culinary medicine into meaningful, sustainable programs that improve pediatric health outcomes. Designed to serve a broad audience, Pediatric Culinary Medicine: Evidence, Opportunities, and Practice is an invaluable tool for researchers seeking to identify gaps and develop impactful studies and for pediatric healthcare providers aiming to implement evidence-based practices. It provides the foundational knowledge, successful models, and training resources needed to harness the power of food to transform child health. This book is a must-have for anyone committed to shaping the future of pediatric nutrition and wellness through culinary medicine.
  • Diagnosis and Management of Gastrointestinal Bleeding

    • 1 Edición
    • Xingshun Qi + 1 más
    • Inglés
    Diagnosis and Management of Gastrointestinal Bleeding is a comprehensive reference addressing the latest advances in the diagnosis and management of gastrointestinal hemorrhage. This reference responds to the growing body of evidence accumulated in recent years, filling a critical gap where no recent comprehensive resource exists. It targets practicing gastroenterologists and researchers seeking current, evidence-based guidance. The content is systematically organized into 14 chapters covering epidemiology, causes, risk factors, diagnosis, and treatment modalities including medical, endoscopic, and vascular interventional approaches. Special chapters focus on management in children and the elderly. Each chapter is authored by leading experts, providing detailed insights into prevention, treatment, and prognostic assessment of gastrointestinal bleeding. Diagnosis and Management of Gastrointestinal Bleeding equips clinicians with practical knowledge to improve patient care and offers researchers a synthesis of innovative findings and future research directions. Its inclusion of color figures and visual aids enhances comprehension. This reference is an essential resource for those involved in the clinical and research aspects of gastrointestinal bleeding management.
  • Trauma Informed Care in Pediatric Acute and Critical Care Setting

    An Approach for Promoting Resilience and Recovery
    • 1 Edición
    • Trevor A. Hall + 1 más
    • Inglés
    Trauma Informed Care in Pediatric Acute and Critical Care Settings: An Approach for Promoting Resilience and Recovery is a groundbreaking resource addressing the urgent need for trauma-informed care (TIC) in pediatric intensive care units (PICUs) and acute care settings. Each year, countless children and their families navigate the overwhelming challenges of hospitalization due to life-threatening injuries or illnesses. This book explores the profound psychological impacts of such experiences and underscores the necessity of integrating TIC principles to foster resilience and enhance recovery. Within its pages, readers will discover a comprehensive exploration of TIC elements and principles, such as recognizing signs of psychological trauma, ensuring safety, and promoting trustworthiness and empowerment. The text examines pediatric medical traumatic stress, secondary trauma, and the importance of TIC for long-term health outcomes. Featuring contributions from a multidisciplinary team of experts, the book offers practical strategies for developing and sustaining TIC programs. It provides insights into the unique environment of pediatric acute settings, the roles of healthcare professionals, and the global landscape of healthcare systems, while also addressing essential aspects of follow-up care. Trauma Informed Care in Pediatric Acute and Critical Care Settings: An Approach for Promoting Resilience and Recovery equips healthcare professionals with the knowledge to improve patient care, reduce professional burnout, and advance the field of pediatric acute care. With its focus on awareness, readiness, detection, management, and integration of TIC principles, this essential guide is poised to transform the experience of children, families, and healthcare teams by fostering a culture of healing and resilience.
  • AI and Personalized Medicine in Cardiometabolic Disease

    Principles, Applications and Future Perspectives
    • 1 Edición
    • M. Salman Khan + 2 más
    • Inglés
    AI and Personalized Medicine in Cardiometabolic Disease: Principles, Applications and Future Perspectives offers a comprehensive and timely exploration of how artificial intelligence (AI) is revolutionizing personalized care for cardiometabolic diseases. This authoritative volume bridges foundational AI concepts with cutting-edge translational applications, guiding clinicians, researchers, and data scientists through the integration of AI-driven tools in diagnosis, risk prediction, biomarker discovery, and tailored treatment strategies. Featuring real-world case studies, ethical and regulatory insights, and future-focused discussions on emerging technologies and equitable implementation, this book is an essential resource for healthcare professionals and scientists aiming to harness AI’s full potential to improve patient outcomes in cardiovascular and metabolic health.
  • Developments and Recent Trends in Cell and Gene Therapies for Cancer

    • 1 Edición
    • Ranjita Shegokar + 1 más
    • Inglés
    Developments and Recent Trends in Cell and Gene Therapies for Cancer is a comprehensive and strategic reference that explores the scientific foundations, clinical applications, and commercial success of FDA-approved cell and gene therapies. Each chapter focuses on a specific FDA-approved cell or gene therapy product, detailing its development journey, mechanism of action, therapeutic indications, clinical outcomes, regulatory approval, visual data (minimum 4 figures and 3 tables per chapter) and real-world outcomes. The therapies span a wide range of modalities including CAR-T cells, cord blood-derived products, gene editing technologies, and viral vector-based treatments. The chapters are authored by subject matter experts from academia, clinical institutions, and industry, ensuring authoritative and up-to-date content. With contributions from leading experts in academia and industry, the book highlights innovations in CAR-T, cord blood, and gene editing technologies, featuring therapies from companies such as Bristol-Myers Squibb, Pfizer, and Janssen. Designed with modular chapters and rich visual content, it serves both as a scientific resource and a practical guide for oncologists, researchers, biotech professionals, and regulatory stakeholders navigating the evolving landscape of cancer treatment.
  • Rational 'Co-Design' of Targeted Anticancer Therapeutics

    Integrating Immuno-Oncology, Biomaterials, and Translational Systems
    • 1 Edición
    • Y. Manojkumar + 3 más
    • Inglés
    Rational 'Co-Design' of Targeted Anticancer Therapeutics: Integrating Immuno Oncology, Biomaterials, and Translational Systems presents a unified, system level framework that designs molecules, carriers, and delivery pathways concurrently for clinically translatable cancer therapies. The book details how electronic structure, molecular recognition, biomaterial compatibility, immune microenvironment dynamics, and ADMET/AI models integrate into end to end decision frameworks—from in silico prediction to experimental validation and regulatory readiness. Readers gain a pragmatic path to faster, safer translation: case informed guidance, co design checklists, and criteria for affordability, scalability, and sustainability enable researchers and advanced students to move beyond fragmented, sequential development toward robust therapeutic systems.
  • Artificial Intelligence in Clinical Medicine

    General Concepts and Specific Applications
    • 1 Edición
    • Marianne Legato J + 1 más
    • Inglés
    Artificial Intelligence in Clinical Medicine: General Concepts and Specific Applications explores the evolution and application of artificial intelligence (AI) in medicine, highlighting both its potential and challenges. The initial discussion outlines past failures in integrating AI into healthcare, followed by a review of FDA-approved AI medical devices and their implications for diagnostics. Subsequent sections examine the transformative impact of large language models, the ethical application of AI in clinical settings, and the role of AI in enhancing patient safety. Various specialties, such as cardiology and pulmonary disease, illustrate AI's capabilities in improving diagnostics and treatment. The discussions extend to diabetes care, dermatology, obstetrics, and radiology, emphasizing the need for ethical considerations and quality assessments to ensure AI aligns with human values and improves patient outcomes across diverse healthcare contexts.
  • The Plasticity of Sex

    The Molecular Biology and Clinical Features of Genomic Sex, Gender Identity and Sexual Behavior
    • 2 Edición
    • Marianne Legato J
    • Inglés
    The Plasticity of Sex: The Molecular Biology and Clinical Features of Genomic Sex, Gender Identity and Sexual Behavior, Second Edition offers a thorough exploration of the biological, clinical, and social dimensions of human sexuality. This updated edition emphasizes the increasing recognition of the diversity of sexual identities and behaviors, particularly the spectrum between traditional male and female categories. It consolidates evidence-based research on the molecular and developmental biology of sex, gender identity, and sexual behavior, presenting a comprehensive resource for biomedical researchers, clinicians, and medical students. A key theme of this edition is the growing understanding of human sexuality as fluid and diverse, shaped by a variety of genetic, hormonal, and environmental factors. Over recent decades, there has been heightened interest in issues like gender identity, genital ambivalence, and sexual transition, with both the general public and medical professionals seeking more knowledge and guidance on these topics. The book underscores the need for a more inclusive approach, incorporating voices from diverse communities and recognizing the importance of broadening the scope of research beyond narrow sample sizes and traditional binary frameworks. The new edition highlights the ongoing challenges in understanding and addressing variations in human sexuality and the need for continued dialogue between science, society, and legal systems to create more inclusive frameworks for care and support. This work serves as an essential reference for anyone involved in the study or treatment of human sexuality.
  • Translational Insights in Regenerative Medicine

    • 1 Edición
    • Volumen 228
    • Inglés
    Progress in Molecular Biology and Translational Science series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.
  • Avian Models of Development

    • 1 Edición
    • Volumen 173
    • Inglés
    Avian Models of Development provides practical and experimental approaches for using avian systems to study developmental processes. It covers key methods, model applications, and emerging techniques that support research in embryogenesis, tissue formation, gene function, and developmental mechanisms.
  • Medical and Health Genomics of South Asia

    • 1 Edición
    • Dhavendra Kumar + 1 más
    • Inglés
    Medical and Health Genomics of South Asia, a new volume in the Genomic and Precision Medicine in Clinical Practice series, offers a thorough discussion of medical genomics as applied across South Asian nations, from India to Pakistan, Bangladesh, Sri Lanka, and Nepal, as well as in South Asian populations abroad. Here, global chapter authors consider genomic variation and the population heterogeneity of genetic, infectious, and lifestyle diseases in South Asia, along with successful modes of population health management for these inherited disorders and other applications of clinical genomics for improved individual health in the region. Adopting an applied approach, this book first reviews basic genomic models and population study formats, as well as the anthropological and genetic history of South Asia. The following sections examine genomic epidemiology and population health in the South Asian context; examples of genomic medicine's use in combating major health challenges in the region; genomic healthcare infrastructure; and related social, ethical, legal, and economic aspects central to impactful genomic medicine.
  • Aging and Troponin

    Clinical Implications and Uses Beyond Diagnosis
    • 1 Edición
    • Gary Tse + 3 más
    • Inglés
    Aging and Troponin: Clinical Implications and Uses Beyond Diagnosis examines the multifaceted role of troponin in clinical medicine, with a special focus on aging. This comprehensive reference provides essential technical knowledge, diagnostic and prognostic applications, and model development insights from leading experts in clinical biochemistry, pathology, and epidemiology. The book emphasizes the impact of aging on troponin test results and their interpretation, addressing age-related disorders such as renal failure. Sections cover the technical aspects of troponin assays, comparing traditional and high-sensitivity assays and exploring point-of-care testing advancements.The book also examine age-related changes and intra- and inter-individual variability in troponin levels, focuses on diagnostic applications, including troponin as a biomarker for cardiac injury and dysfunction, and the effects of age, sex, and renal impairment on diagnostic sensitivity and specificity, and discusses troponin's prognostic value for mortality in various conditions, including heart disease, sepsis, and COVID-19, and its role as a marker of organ biological age. The final section offers cutting-edge insights into the clinical applicability of troponin testing, highlighting the benefits of incorporating high-sensitivity assays into clinical workflows and providing perspectives and age-related considerations from practicing physicians on implementation and evidence-based practice.
  • Anorectal Malformations

    • 1 Edición
    • Ivo de Blaauw + 2 más
    • Inglés
    Anorectal Malformations is an essential resource for pediatric surgical specialists and caregivers, providing a comprehensive approach to the diagnosis, treatment, and follow-up of patients with anorectal malformations. This book not only covers the latest surgical techniques but also delves into the intricacies of the condition, offering structured advice from a trusted organization, ERN eUROGEN, and addressing the significant gaps in literature related to this rare disease. The handbook is meticulously organized, beginning with an introduction to the ERN eUROGEN and ARMnet networks, followed by an exploration of key topics such as anatomy, embryology, genetics, and epidemiology of anorectal malformations. It details surgical procedures, including colostomy and reconstruction techniques, as well as non-surgical treatments for common complications like constipation and incontinence. The book also emphasizes long-term outcomes, global care networks, and patient perspectives, ensuring a holistic understanding of the patient journey.Anorectal Malformations is invaluable for clinicians, researchers, and healthcare professionals, providing the necessary insights to make accurate diagnoses, perform effective surgeries, and ensure proper follow-up care. It serves as a critical reference guide for anyone involved in the care of patients with anorectal malformations, ultimately improving clinical outcomes and enhancing the quality of life for affected individuals and their families.
  • Biomechanics of the Heart

    From Model to Patient
    • 1 Edición
    • Patrick Clarysse + 3 más
    • Inglés
    Biomechanics of the Heart: From Model to Patient provides readers with a comprehensive overview of the modeling and assessment of the heart’s biomechanics. The book addresses topics such as the physiology of normal and diseased hearts, cardiovascular imaging, modeling of myocardial tissue in the passive and active states, as well as state-of-the-art approaches for patient specific modeling of the heart’s mechanical function. This is all augmented by case studies and examples of exploitation of models for computer-aided diagnosis, treatment, and monitoring of heart diseases. Readers are introduced to modeling of the heart’s anatomical and muscular structure, a review of imaging techniques to analyze the geometry, content and dynamics of the heart, as well as an in-depth look at the biomechanical properties of normal and diseased hearts. Finally, chapters cover modeling cardiac passive and contractile mechanics, biomechanical finite element simulations of the heart, patient-specific modeling of the heart and circulatory system, as well as the exploitation of models for computer-aided diagnosis, treatment, and monitoring of heart diseases.
  • Self-Learning AI in Healthcare

    Agentic Systems for Smarter Medicine
    • 1 Edición
    • Rajesh Kumar Dhanaraj + 4 más
    • Inglés
    Self-Learning AI in Healthcare: Agentic Systems for Smarter Medicine covers the transformative potential of advanced artificial intelligence within modern medicine. The book addresses the critical need for self-learning and agentic AI systems that autonomously adapt, refine decision-making, and navigate complex clinical environments with minimal intervention. Chapters provide foundational insights into the rise of self-learning AI and neural networks tailored for adaptive medical systems. Subsequent chapters delve into unsupervised, semi-supervised, and reinforcement learning for autonomous healthcare decision-making, alongside decentralized edge AI approaches. Specialized sections cover personalized medicine, hospital workflow optimization, remote patient monitoring, early disease detection, federated learning for privacy preservation, and more.Further, this book explores AI applications in drug discovery, mental health support, radiology, digital twins, and medical robotics, culminating with an examination of future challenges, ethics, and regulatory frameworks shaping self-learning AI’s trajectory in healthcare. It is tailored to serve a diverse yet specialized audience spanning academic, professional, and research sectors. Healthcare IT professionals and clinical informatics specialists will gain practical guidance for implementing adaptive AI solutions within complex healthcare environments. AI researchers and data scientists focused on developing self-learning models will find cutting-edge methodologies and case studies that advance medical applications.
  • SGLT2 Inhibitors in Cardiovascular Diseases

    Mechanisms, Clinical Impact, and Future Directions
    • 1 Edición
    • Tong Liu
    • Inglés
    SGLT2 Inhibitors in Cardiovascular Diseases: Mechanisms, Clinical Impact, and Future Directions reviews the impact of SGLT2 inhibitors on cardiovascular health in individuals with type 2 diabetes, chronic kidney disease, heart failure, and atherosclerosis. The book synthesizes preclinical and clinical evidence to highlight the cardiovascular benefits of these drugs, initially developed for hyperglycemia management. It details recent studies on SGLT2 inhibitors' effects on cognitive dysfunction, sudden death, ventricular arrhythmias, heart remodeling, and cancer risks in diabetic patients.In addition, it compares SGLT2 inhibitors with DPP4 inhibitors, emphasizing the efficacy of empagliflozin and dapagliflozin in reducing syncope and cardiovascular mortality, supported by trials like EMPA-REG OUTCOME and DECLARE-TIMI 58. Addressing a gap in literature, the book provides a comprehensive overview of SGLT2 inhibitors' cardiovascular benefits in high-risk populations, including atrial fibrillation and syncope. It offers valuable insights and recommendations for clinicians, researchers, and policymakers managing cardiovascular risk.
  • RNA-Binding Proteins Part B

    • 1 Edición
    • Volumen 744
    • Inglés
    Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.
  • Rare and Complex Liver Diseases

    • 1 Edición
    • Ansgar Wilhelm Lohse + 2 más
    • Inglés
    Rare and Complex Liver Diseases is a comprehensive guide that fills a critical gap in the literature, providing up-to-date, practical advice. The book is organized into distinct sections, each dedicated to a specific category of liver diseases. Topics covered include Autoimmune Liver Diseases such as Autoimmune Hepatitis (AIH) and Primary Biliary Cholangitis (PBC); Cholestatic Liver Diseases including Biliary Atresia and Alagille Syndrome; Vascular Liver Diseases like Budd-Chiari Syndrome and Non-cirrhotic Portal Hypertension; Metabolic Liver Diseases such as Wilson Disease and Alpha-1 Antitrypsin Deficiency; Structural Liver Diseases including Polycystic Liver Disease; and Rare Liver Tumors like Cholangiocarcinoma and Hemangioendothelioma... chapters cover Liver Disease in Pregnancy and delve into Quality of Life issues, offering evidence-based insights and practical strategies for improving patient well-being. This book serves as an indispensable resource for gastroenterologists, hepatologists, internists, and researchers specializing in liver diseases. It equips these professionals with the knowledge and practical advice necessary to improve patient outcomes and advance their field of study.
  • Insights and Implications of Pseudo Esterase Activity of Human Serum Albumin in Diabetic Kidney Disease

    • 1 Edición
    • Dibyajyoti Banerjee
    • Inglés
    Insights and Implications of Pseudo Esterase Activity of Human Serum Albumin in Diabetic Kidney Disease provides a comprehensive exploration of diabetic nephropathy, emphasizing the critical need for early detection methods prior to the onset of microalbuminuria. The book's primary focus is on the study of pseudoesterase activity in urinary albumin and other proteins as a potential biomarker for early diagnosis of diabetic kidney disease. This resource bridges a significant gap in current literature by providing an in-depth analysis of how this enzymatic activity can inform the classification and management of diabetic nephropathy.Chapters cover foundational knowledge of diabetes and its complications, the mechanisms of diabetic nephropathy, and detailed discussions on human serum albumin and its enzymatic activities. Each chapter covers the biochemical characterization of pseudoesterase activity, methods for its detection, and the significance of urinary proteomic profiling. Final chapters highlight future research opportunities and the potential for developing point-of-care testing tools, positioning this work as a critical resource for advancing the field of diabetic kidney disease research and clinical practice.
  • Chronic Kidney Disease Management Through Herbal Phytoceuticals

    Mechanistic Findings and Phyto-Based Therapy for Chronic Kidney Disease Management
    • 1 Edición
    • Kalicharan Sharma
    • Inglés
    Chronic Kidney Disease Management Through Herbal Phytoceuticals: Mechanistic Findings and Phyto-Based Therapy for Chronic Kidney Disease Management examines chronic kidney disease (CKD) through the lens of plant-, marine-, and microbe-derived compounds. The field increasingly requires safer, non-invasive therapies that complement existing regimens while clarifying mechanisms of action. By combining ethnobotanical knowledge with contemporary computational methods, this work serves as a translational resource for researchers, clinicians, and students seeking evidence-based, mechanism-driven phytopharmaceutical approaches to nephroprotection and disease modification. Readers gain a framework for integrating traditional knowledge with modern drug discovery pipelines. The table of contents outlines a progression from foundational concepts to translational applications. Chapters 1–3 cover the global burden, pathophysiology, and current management of CKD. Chapter 4 identifies druggable molecular targets. Chapters 5–7 survey plant-based phytoceuticals for CKD management, marine natural products as emerging CKD therapies, and microbial-derived candidates as potential CKD agents, supported by efficacy and safety data. Chapters 8–9 apply molecular docking and docking-based mechanistic insights to plant, marine, and microbial compounds. Chapters 10–12 address clinically validated phytopharmaceuticals... formulation science, and global regulatory considerations. Chapter 13 presents clinical and preclinical case studies to illustrate practical applications. This book delivers clear benefits to end users by providing integrated, mechanism-driven insights that connect basic science to clinical decision-making. Readers gain access to curated data on plant-, marine-, and microbial-derived compounds along with their targets, efficacy, and safety, supported by docking-based mechanistic validation. It also addresses formulation challenges, regulatory pathways, and quality-control considerations essential for translating phytopharmaceuticals from bench to bedside, including safety assessment and scalable product development. This blend of theory and practical guidance supports researchers designing studies, clinicians implementing evidence-based phytotherapy, and educators teaching multidisciplinary approaches to CKD management across academic and clinical settings.
  • Artificial Intelligence in Immunoengineering

    Methods, Models, and Translational Applications
    • 1 Edición
    • Steven Zanganeh + 1 más
    • Inglés
    Artificial Intelligence in Immunoengineering: Methods, Models, and Translational Applications examines how AI reshapes immunoengineering to design immune-modulating biomaterials, imaging systems, and diagnostic tools. The book presents an integrated view of data-driven approaches that accelerate discovery and translation in biomedicine. It surveys biological data from single-cell to spatial omics and proteogenomics and offers practical machine learning frameworks, generative and mechanistic models, and multimodal integration strategies. Sections address bench-to-bedside translation, validation pipelines, and regulatory considerations for AI-enabled immunoengineering tools.The book highlights the rapid progress of multidisciplinary research within immunotherapy and immunoengineering. Looking forward, the prospects of immunoengineering appear promising, with further advancements in disease prevention, diagnostics, and treatment on the horizon. Graduate students, academic researchers, clinician-scientists... and computational biologists will gain standardized workflows, mechanism-aware modeling, and reproducible pipelines that advance immunotherapies and diagnostics from concept to clinical impact.
  • Evidence Based Diagnosis and Management of Testicular Tumors

    • 1 Edición
    • Axel Heidenreich
    • Inglés
    Evidence Based Diagnosis and Management of Testicular Tumors is a comprehensive reference that addresses the current needs of urologists, oncologists, and related specialists involved in testicular cancer care. This book synthesizes the latest research, clinical guidelines, and expert insights to facilitate accurate diagnosis, staging, and personalized treatment strategies. It emphasizes a multidisciplinary approach, integrating pathology, molecular genetics, imaging, and surgical techniques, to optimize patient outcomes and minimize long-term toxicity. The contents are organized into key sections covering epidemiology, pathology, staging, diagnostic evaluation, disease management, and follow-up. Each chapter begins with case scenarios and interactive questions, fostering active learning and decision-making skills. The book also dedicates sections to rare tumors and pediatric cases, ensuring broad applicability across age groups and tumor types. Visual content, including figures, flow charts, tables, and videos, enhances comprehension and procedural training. This reference aims to bridge the knowledge gap in current testicular cancer management, providing practitioners with practical, guideline-conforming advice. It supports clinicians in delivering individualized, risk-adapted care, ultimately improving survival rates and quality of life for patients. By combining expert perspectives with evidence-based protocols, this book serves as an essential resource for advancing clinical practice in testicular oncology.
  • Autophagy – Part D

    • 1 Edición
    • Volumen 407
    • Inglés
    Autophagy – Part D presents current methods and advances in the study of autophagy, covering experimental approaches, molecular mechanisms, and emerging applications across different biological and disease contexts. It serves as a useful resource for researchers investigating autophagy in cell biology, physiology, and translational research.
  • A Comprehensive Guide to Surgical Oncology

    • 1 Edición
    • Aqeel Shakir Mahmood + 2 más
    • Inglés
    A Comprehensive Guide to Surgical Oncology is an authoritative reference that meticulously covers the surgical management of various cancers. Each section delves into the latest surgical techniques, treatment protocols, and post-operative care strategies, supported by up-to-date research and clinical evidence. Enriched with detailed illustrations, case studies, and expert insights, this book is an indispensable resource for professionals and students alike. The primary purpose of this book is to provide a comprehensive, up-to-date resource that addresses the current challenges and advancements in surgical oncology. As cancer treatment evolves rapidly with continuous improvements in surgical techniques and multidisciplinary care, there is a pressing need for a new resource that synthesizes these developments into a coherent guide. This book aims to fill that gap by offering a thorough overview of the latest surgical oncology practices, thereby enhancing the knowledge and skills of its readers. This book solves several key problems for its readers by bridging the gap between rapidly advancing research and clinical practice, ensuring access to the latest information. It consolidates a vast amount of information into one comprehensive volume, saving readers the time and effort of consulting multiple sources. Providing practical guidance on the surgical management of a wide range of cancers, it helps practitioners make informed decisions in clinical settings. For students and trainees, it serves as a valuable educational tool that covers both foundational knowledge and advanced concepts in surgical oncology, offering multidisciplinary insights that foster a better understanding of the collaborative efforts required in cancer treatment.
  • Cell Death Part G

    • 1 Edición
    • Volumen 214
    • Inglés
    Cell Death Part G presents current methods and advances for studying the mechanisms, regulation, and biological significance of cell death. The volume covers experimental and analytical approaches relevant to apoptosis, necrosis, autophagy, and other cell death pathways in both basic and translational research.
  • Algal Bioprospecting and Bioprocessing

    Current Trends and Future Perspectives
    • 1 Edición
    • Nitin Trivedi + 1 más
    • Inglés
    Algal Bioprospecting and Bioprocessing: Current Trends and Future Perspectives explores the rapidly evolving field of algal biotechnology and emphasizes the increasing importance of marine and freshwater algae as sustainable sources of bioproducts. By highlighting recent advancements and industrial applications, it aims to promote translational research and promote a circular bioeconomy within the blue economy framework. The book covers a wide array of topics, including algal biomass processing, bioactive metabolites, proteins, pigments, and biorefinery strategies. Key chapters look into advanced extraction techniques, genetic engineering, and the development of high-value products such as omega-3 fatty acids, oligosaccharides, and biopolymers. The book also explores the role of algae in sustainable agriculture, aquaculture, biofuel production, and space missions, providing a holistic view of current research and future prospects. Algal Bioprospecting and Bioprocessing: Current Trends and Future Perspectives is primarily for university students, academics, researchers, and professionals interested in applied phycology and marine biotechnology. This book also appeals to aspiring algapreneurs, industry experts, and policymakers. It encourages a scientific approach to harnessing algae’s societal benefits and promotes understanding of innovative technologies transforming micro- and macroalgae into valuable industrial products within a sustainable, circular economy.
  • Pioneering Precision in Cancer Treatment through 3D Bioprinting

    • 1 Edición
    • Anand Krishnan + 3 más
    • Inglés
    Pioneering Precision in Cancer Treatment through 3D Bioprinting explores the transformative impact of 3D bioprinting on cancer therapy. This groundbreaking book examines innovative techniques revolutionizing cancer care, from creating patient-specific tumor models to accelerating drug discovery and enabling personalized treatments. It offers a comprehensive look at how 3D bioprinting is reshaping oncology. The book details the creation of intricate tumor models that mimic the in vivo environment, enabling precise drug testing and individualized treatment plans. It highlights 3D bioprinting's role in drug screening, tumor modeling, and creating implantable scaffolds for cancer treatment.By manipulating cell arrangements and microenvironments, 3D bioprinting produces accurate cancer models. For the academic audience, this book blends bioengineering, medical insights, and real-world applications. It provides valuable case studies and developments in 3D cancer model creation, enhancing the understanding of oncogenesis, tumor progression, and therapy responses.
  • Omics Approaches in Rhizosphere Microbiology: Part B

    • 1 Edición
    • Volumen 61
    • Inglés
    Omics Approaches in Rhizosphere Microbiology: Part A offers a definitive, systems-level exploration of the complex microenvironment where plant roots and soil microorganisms interact. As global agriculture faces the dual challenges of climate change and food insecurity, understanding the rhizosphere has shifted from traditional culture-dependent isolation to advanced high-throughput molecular auditing. This volume serves as a comprehensive, technically rigorous manual and structural roadmap, bridging foundational rhizosphere biology with the cutting-edge structural analytical tools of modern polyphasic science.
  • Artificial Intelligence Based Primary Care

    Artificial Intelligence and Human Cognition in General Practice and Family Medicine
    • 1 Edición
    • Anthony C. Chang + 5 más
    • Inglés
    Artificial Intelligence Based Primary Care: Artificial Intelligence and Human Cognition in General Practice and Family Medicine provides a comprehensive look into the integration of artificial intelligence within primary care. This book aims to bridge the gap between data scientists and primary care clinicians by presenting potential AI applications, implementation challenges, and real-world clinical scenarios in an accessible manner. Comprised of 5 sections and 20 chapters, it offers both theoretical insights and practical guidance for family medicine practitioners.Additi... the book includes a chapter dedicated to a day in the life of a General Practitioner, showcasing the practical impact of AI. It also features an extra compendium listing the Top 100 articles and best books on Artificial Intelligence. This resource is invaluable for academics, researchers, and clinicians eager to expand their knowledge in this emerging field.
  • Management of Chronic Kidney Disease and Its Complications

    • 1 Edición
    • Thakur Gurjeet Singh + 4 más
    • Inglés
    Management of Chronic Kidney Disease and Its Complications  presents the latest scientific advances in diagnosing and managing Chronic Kidney Disease (CKD) and its diverse complications. This authoritative text covers molecular mechanisms such as inflammation and oxidative stress, genetic and epigenetic factors, and explores cutting-edge technologies including artificial intelligence and regenerative medicine. With detailed chapters on cardiovascular, metabolic, neurological, and hematological complications, the book offers a holistic approach to understanding CKD’s complexity and evolving treatment strategies.The book’s content is organized to provide a thorough exploration of CKD, beginning with foundational topics like genetic contributions and diagnostic evaluation, progressing through specific complications such as diabetic nephropathy, hypertension, and urologic conditions. Special focus is given to management strategies, nutritional interventions, and unique considerations in pediatric, geriatric, and pregnant populations. Emerging therapies, including precision medicine, gut microbiota modulation, and AI-driven early detection, are also extensively covered to keep readers at the forefront of nephrology research and clinical practice.Management of Chronic Kidney Disease and Its Complications is an essential resource for nephrologists, general practitioners, medical students, nursing professionals, and healthcare providers involved in kidney disease care and research.
  • Applications of Microfluidics Device Technology

    • 1 Edición
    • Volumen 227
    • Inglés
    Microfluidics is a rapidly expanding field that is recognized as a powerful platform for accelerating biological science research and innovation. It has the potential to reduce the cost and reagent consumption by enabling the precise manipulation of a small amount of fluids through microchannel ranging from ten to hundreds micrometres in size. It is a multidisciplinary domain, which integrates molecular analysis, molecular biology, and microelectronics. It has demonstrated practical applications in the design and fabrication of systems capable of processing low volumes of fluids while enabling multiplexing, automation, and high-throughput screening. Since its emergence in early 1980s, microfluidics has significantly contributed in the development of inkjet printheads, DNA chips, lab-on-a-chip technology, micro-propulsion, and micro-thermal technologies. Microfluidic chips comprise intricate networks of microchannels and chambers designed to manipulate fluids at the microscale. This volume highlights the applications of microfluidics in the detection and analysis of infectious diseases caused by bacteria, viruses, fungi, and protozoa. It also explores the use of microfluidic technologies in the diagnosis and study of non-infectious diseases, including cardiovascular disorders, cancer, metabolic diseases, and neurological conditions. It also covered single-cell analysis, high-throughput drug screening, cell sorting, and both preclinical and clinical applications. It also used in role of microfluidics in organ culture, regenerative medicine, and personalized healthcare. It also addresses ethical and regulatory issues in the development and use of microfluidic devices. This volume is designed to serve as valuable resource for students, researchers, scientists, clinicians, stakeholders, policymakers, and practitioners to understand microfluidics and apply microfluidics technology/devices in various fields. It provides a strong foundation to help the extension of microfluidics knowledge and accelerate research, innovation, technology and practical applications.
  • Federated Quantum Convolutional Neural Networks in Healthcare

    Enhancing Privacy and Efficiency
    • 1 Edición
    • Abhishek Kumar + 3 más
    • Inglés
    Federated Quantum Convolutional Neural Networks in Healthcare: Enhancing Privacy and Efficiency explores the innovative intersection of quantum computing and federated learning in the context of healthcare. As medical data grows exponentially and privacy concerns intensify, this book addresses the urgent need for secure, scalable AI solutions that enable collaborative data analysis without compromising patient confidentiality. It offers a detailed examination of the theoretical foundations of quantum machine learning and federated systems, complemented by practical case studies spanning medical imaging, genomics, and disease diagnosis. The content delves into architecture design, security protocols, and optimization techniques, equipping researchers and practitioners with the tools to develop privacy-preserving AI models tailored for medical applications. The book also discusses regulatory considerations, deployment challenges, and future research directions, positioning itself as a vital resource for advancing healthcare AI. Its comprehensive approach bridges fundamental science and real-world implementation, empowering healthcare professionals, data scientists, and policy makers to harness next-generation quantum federated systems for improved patient outcomes and data security. This resource is essential for those seeking to implement cutting-edge AI technologies in healthcare, ensuring secure, efficient, and collaborative medical data analysis.
  • Introduction to Bioinformatics and Machine Learning

    • 1 Edición
    • Milana Frenkel-Morgenstern
    • Inglés
    Introduction to Bioinformatics and Machine Learning provides comprehensive instruction in modern computational biology by integrating bioinformatics, genomics, artificial intelligence, and machine learning into a unified learning framework. The book bridges the gap between biological data analysis and computational methods, covering fundamental concepts in molecular biology and bioinformatics together with practical applications of machine learning to genomics, transcriptomics, proteomics, microbiome research, structural biology, NGS technologies, liquid biopsy, cancer genomics, and precision medicine. Readers are introduced to DNA and RNA sequencing technologies, genome assembly, sequence alignment, variant discovery, gene expression analysis, fusion gene detection, protein structure prediction, biological databases, statistical analysis, explainable artificial intelligence, and predictive modeling. Throughout the book, real-world biomedical case studies demonstrate how computational methods are transforming modern biological and clinical research; and both bioinformatics and machine learning are addressed in a coherent and accessible manner, emphasizing practical problem-solving, reproducible computational workflows, and biological interpretation of results.Designed for upper-level undergraduate students, graduate students, and researchers, this book serves as both a classroom textbook and practical assignments for those working at the interface of biology, computer science, medicine, and data science.
  • Hypoxia-induced Tumor Heterogeneity and Immune Evasion

    Clinical Interventions
    • 1 Edición
    • Benjamin Bonavida + 1 más
    • Inglés
    Hypoxia-induced Tumor Heterogeneity and Immune Evasion: Clinical Interventions explores how hypoxic stress within the tumor microenvironment drives cancer progression, immune escape, and resistance to therapy. The volume integrates foundational and cutting-edge insights into tumor biology, immunology, and therapeutic innovation. It is structured into five parts, covering tumor heterogeneity, hypoxia-driven mechanisms, immune evasion, clinical diagnostics, and future directions. Topics include metabolic reprogramming, angiogenesis, immune suppression, and hypoxia-targeted therapies, with emphasis on translational relevance.By bringing together global experts to examine how hypoxia shapes tumor evolution, alters immune responses, and influences treatment outcomes, this resource benefits researchers, clinicians, and advanced students by offering a comprehensive, up-to-date synthesis of a rapidly evolving field. It supports deeper understanding of tumor complexity and equips readers with knowledge to inform experimental design, clinical strategies, and therapeutic development in oncology.
  • Plant Development

    • 1 Edición
    • Volumen 172
    • Inglés
    Plant Development provides an overview of the fundamental processes that govern the growth, differentiation, and organization of plants throughout their life cycle. The book explores key developmental stages, from embryogenesis and seed germination to organ formation, flowering, and senescence, highlighting the genetic, molecular, cellular, and environmental factors that regulate these events. By integrating classical concepts with modern advances in developmental biology, the volume offers valuable insight into how plants establish form, adapt to their surroundings, and coordinate growth in response to internal and external signals. It serves as a useful resource for researchers, students, and professionals interested in plant biology, developmental mechanisms, and related fields.
  • Federated Intelligence in Medicine

    AI-Driven Robotics for Secure and Intelligent Healthcare Systems
    • 1 Edición
    • Manisha Guduri + 3 más
    • Inglés
    Federated Intelligence in Medicine: AI-Driven Robotics for Secure and Intelligent Healthcare Systems explores the rapidly evolving field where medical robotics intersects with cutting-edge artificial intelligence and secure data-sharing technologies. Covering a comprehensive range of topics, the book begins with foundational knowledge in medical robotics and Generative AI, progressing to advanced concepts such as federated learning and architectural modeling tailored for AI-driven robotic systems. Readers will explore algorithms enhancing surgical robotics, remote robotic surgeries, and human-robot interaction. The text also tackles AI-driven diagnostic robots, privacy preservation through homomorphic encryption, and differential privacy and emerging medical imaging techniques integrated with robotics.Later chapters examine the synergy of large language models, agent AI, and edge AI with robotic technologies, providing both theoretical frameworks and practical case studies that illuminate real-world applications and challenges. This book is an invaluable resource for researchers and academicians engaged in artificial intelligence, robotics, and medical technology. It also serves undergraduate and graduate students in Biomedical Engineering, Electronics and Electrical Engineering, and Computer Science and Engineering.
  • Implications of Artificial Intelligence in Next Generation Physiotherapy

    • 1 Edición
    • Manpreet Kaur + 3 más
    • Inglés
    Implications of Artificial Intelligence in Next Generation Physiotherapy explores how artificial intelligence is transforming the future of physiotherapy across the entire continuum of rehabilitation. Covering musculoskeletal, neurological, cardiopulmonary, sports, paediatric, geriatric, women's health, and community-based physiotherapy, the book highlights how AI is reshaping clinical practice through intelligent assessment, precision rehabilitation, personalized treatment planning, predictive analytics, remote monitoring, and data-driven clinical decision-making.The book presents comprehensive coverage of emerging AI technologies, including machine learning, deep learning, computer vision, wearable sensors, robotics, virtual and augmented reality, digital twins, tele-rehabilitation, and intelligent clinical decision support systems. It also discusses workload monitoring, movement analysis, biomechanical assessment, functional outcome prediction, patient engagement, and continuous recovery tracking, supported by current research, real-world applications, and clinical case studies.Designed for researchers, clinicians, educators, students, and healthcare innovators, this book bridges the gap between cutting-edge artificial intelligence and evidence-based physiotherapy practice. By examining both current applications and future directions, it provides readers with the knowledge required to implement AI-driven innovations that enhance diagnostic accuracy, optimize rehabilitation outcomes, improve healthcare accessibility, and advance patient-centred care in the next generation of physiotherapy.
  • Endoscopic/Robotic Thyroidectomy Surgery

    Using the Gasless Unilateral Axillary Approach
    • 1 Edición
    • Chuanming Zheng + 1 más
    • Inglés
    Endoscopic/Robotic Thyroidectomy Surgery: Using the Gasless Unilateral Axillary Approach is a comprehensive and systematic resource on endoscopic/robotic thyroidectomy using the gasless unilateral axillary approach comprehensive and systematically presented resource on the gasless axillary approach to endoscopic/robotic thyroidectomy. It includes a detailed introduction to all aspects of surgical treatment including anesthesia coordination and robotic surgery. The book provides practical guidance on postoperative complication management and postoperative care and describes specific methods for technical simulation training and functional exercises. While many journal papers on specific aspects of this surgical approach have been published, no book is currently available.
  • Advances in Hepatorenal Syndrome Research

    Untangling Pathophysiology, Improving Diagnostic Strategies, and Leveraging Therapeutic Innovations
    • 1 Edición
    • Justin Belcher
    • Inglés
    Advances in Hepatorenal Syndrome Research: Untangling Pathophysiology, Improving Diagnostic Strategies, and Therapeutic Innovations is a comprehensive review of the historical perspectives, prevalence, and prognosis of HRS, offering insights into its evolving clinical recognition and shifting paradigms of pathophysiology. Explore the multifaceted pathophysiology of HRS as experts navigate the complexities of cardiac dysfunction, inflammatory cytokines, and other modern understandings shaping the field. Explore differential diagnosis, uncovering alternative etiologies and current diagnostic criteria, while shedding light on biomarkers and novel diagnostic tests revolutionizing patient assessment. Contents will also guide readers through the utility of point-of-care ultrasound in intravascular volume assessment sets the stage for exploring medical therapy options, including vasoconstrictors and albumin usage. Written by a team of experts, this comprehensive reference highlights the intricate pathophysiology of hepatorenal syndrome while delivering the most up-to-date insights into diagnostic and therapeutic approaches. Historically overshadowed by grim prognoses, hepatorenal syndrome has undergone a renaissance of interest due to recent breakthroughs, revolutionizing treatment paradigms. Whether you're a seasoned practitioner or a burgeoning researcher immersing yourself in this dynamic field, this resource offers a thorough examination, encompassing novel diagnostic criteria, innovative biomarkers, and state-of-the-art treatments.
  • Artificial Intelligence in Point-of-Care Nanobiosensors Technology

    Enhancing Disease Diagnostics and Improved Healthcare Outcomes
    • 1 Edición
    • Tharmaraj Vairaperumal + 2 más
    • Inglés
    Artificial Intelligence in Point-of-Care Nanobiosensors Technology: Enhancing Disease Diagnostics and Improved Healthcare Outcomes delves into the revolutionary integration of artificial intelligence (AI) with nanobiosensors to elevate point-of-care (POC) diagnostics for both communicable and non-communicable diseases. Readers will find insightful chapters covering topics ranging from foundational AI and machine learning techniques to specific applications in cardiovascular disease, diabetes, cancer, chronic respiratory ailments, and infectious diseases. Each chapter not only highlights recent breakthroughs in nanobiosensors but also emphasizes the pivotal role of AI in enhancing diagnostic accuracy and facilitating personalized health interventions. Additional discussions around regulatory considerations and the future landscape of AI in biomedical research make this an essential read for those navigating this rapidly evolving field. This book primarily targets researchers and professionals engaged in the interdisciplinary realms of AI, nanomaterials, and biomedical sciences. By providing a critical understanding of emerging AI-based diagnostic technologies and their applications in POC settings, this book fosters collaboration across diverse scientific domains.
  • Neurogenetic Therapies

    Advancements in Treating Nervous System Disorders
    • 1 Edición
    • Ashutosh Pareek + 4 más
    • Inglés
    Neurogenetic Therapies: Advancements in Treating Nervous System Disorders offers a comprehensive resource on the latest gene therapy techniques and their applications in treating neurological disorders. The book delves into various gene therapy methods, including genomic DNA-based therapies, vector-mediated delivery, and RNA interference-based gene silencing. It explores the use of these techniques in treating conditions such as Alzheimer's disease, Parkinson's disease, spinal muscular atrophy, and Duchenne muscular dystrophy. Key topics include the molecular and genetic basis of nervous system disorders, the role of epigenetics, and the development of stem cell and genome editing therapies.With contributions from leading experts, the book also addresses regulatory and ethical considerations in gene therapy, providing a balanced perspective on the challenges and opportunities in this rapidly evolving field. Case studies and practical examples illustrate successful gene therapy treatments, offering valuable insights into translating research into clinical practice. This book is an essential resource for students, researchers, and scientists in neurogenetics, neurology, and molecular biology, as well as clinicians interested in the mechanisms and treatment of neurodegenerative diseases.
  • 3D Bioprinting and Bio-Regenerative Medicine for Personalized Oncology

    Innovations for Personalized Oncology
    • 1 Edición
    • Ashok Kumar + 2 más
    • Inglés
    3D Bioprinting and Bio-Regenerative Medicine for Personalized Oncology: Innovations for Personalized Oncology presents a comprehensive exploration of the transformative role of 3-D bioprinting and bio-generative engineering in modern medicine, with a specific focus on precision oncology. By examining innovative applications of these technologies, the book aims to bridge the gap between emerging scientific advancements and their practical implications in clinical settings. It delves into how patient-specific models of human tissues and organs can revolutionize drug testing, disease diagnostics, and personalized treatment plans, ultimately enhancing the quality of cancer care.Addressing critical challenges in oncology, this book highlights how 3-D bioprinting and bio-generative engineering can improve the accuracy of drug efficacy evaluations, reduce reliance on animal testing, and tackle the pressing issue of organ shortages for transplantation. Furthermore, it emphasizes the ethical considerations and regulatory challenges associated with integrating these technologies into everyday oncology practice, ensuring a balanced perspective on their adoption.