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Elsevier

Libros en Ciencias de la Vida

  • Shared Research Resources

    Best Practices in Management and Administration
    • 1 Edición
    • Joshua Z. Rappoport + 1 más
    • Inglés
    Shared Research Resources: Best Practices in Management and Administration brings together best practices and case studies from research institutions around the world. Covering all areas of management, with examples and applications specific to the research environment, this is the perfect reference to build managerial skills. The first part is dedicated to introducing Shared Research Resources (SRR) management. The second part covers all aspects of staffing. Part three contains complete coverage of operations, including service development, instrument procurement, marketing, management software, customer support, safety, maintenance and repair. Part four is dedicated to fiscal management, budgeting, and reporting.Part five covers strategic management. Part six is devoted to the sustainability of the core facility. The final part covers assessment, including annual reports, program reviews, and audits. This book is a complete reference targeted at SRR managers and staff who need to keep updated with current best practices and case studies. It is also important reading for research institution managers and function leaders.

  • Basics of Sleep Technology

    Fundamentals of Sleep Technology
    • 1 Edición
    • Ravi Gupta + 2 más
    • Inglés
    Basics of Sleep Technology: Fundamentals of Sleep Technology covers the critical elements of sleep and sleep technologies. The book gives a thorough understanding of sleep physiology, neurophysiological concepts, the principles of operation of the numerous equipment types used to diagnosis sleep disorders, and contemporary methodologies for diagnosing sleep disorders. As sleep professionals must understand the fundamentals of signal creation, acquisition principles, and data grading from a sleep diary, actigraphy, and polysomnography, this book provides all of this and more to anyone wishing to develop a comprehensive understanding of sleep.The book underscores that sleep medicine and technology are dynamic and rapidly growing medical specialties, and that one must stay up with the newest innovations in the area, but not at the price of the fundamentals. Users will find a solid background on cutting-edge advances in sleep medicine, diagnostics, monitoring, and therapeutics.

  • Contemporary Practice in Clinical Chemistry

    • 5 Edición
    • William Clarke + 1 más
    • Inglés
    Contemporary Practice in Clinical Chemistry, Fifth Edition is a comprehensive, updated reference and teaching resource focused on Laboratory Medicine, specifically tailored for clinical chemistry faculty, trainees, clinical laboratory scientists, clinical pathologists, and laboratory managers. Edited by renowned experts, the book integrates cutting-edge developments in clinical chemistry with practical applications for professional practice. This new edition covers foundational and advanced topics in clinical chemistry and laboratory medicine, emphasizing the integration of new technologies and methodologies. It addresses precision medicine, medical biotechnology, and artificial intelligence applications within the clinical laboratory setting. The content is designed to support both learning and board exam preparation, providing a deep understanding of the field alongside practical insights.

  • Microbiome-Modulating Strategies in Diabetic Wound Healing

    • 1 Edición
    • Jeena Gupta + 2 más
    • Inglés
    Microbiome-Modulatin... Strategies in Diabetic Wound Healing provides researchers with an in-depth analysis of the wound microbiome’s role in diabetic foot ulcers and chronic wound pathology. This reference elucidates microbial dysbiosis, biofilm formation, and host–microbe interactions that exacerbate impaired healing in diabetic patients. It critically evaluates emerging microbiome-targeted interventions—includ... probiotics, bacteriophages, antimicrobial peptides, and nanotechnology-enabl... drug delivery—supported by the latest molecular, microbiological, and clinical research. The book integrates advanced diagnostic methodologies such as next-generation sequencing and bioinformatics to facilitate precise microbial profiling and personalized therapeutic design. By bridging mechanistic insights with translational and clinical evidence, this resource equips diabetic researchers with comprehensive knowledge to innovate and optimize microbiome-based strategies, ultimately aiming to reduce infection rates, combat antibiotic resistance, and improve regenerative outcomes in diabetic wound management.

  • Flavoproteins and Flavoenzymes

    • 1 Edición
    • Volumen 747
    • Inglés
    Flavoproteins and Flavoenzymes, Volume 738 in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Kirisu2 and KiPaD: global analysis of rapid flavoprotein redox kinetics from stopped-flow multi, ilagros Mendina, A Generic First Approach to Dissecting Flavoenzyme Catalytic Cycles, Removing Covalent Constraints of Protein Loops and Lids by a Split-Gene Strategy, Designing Oxygen Reaction Sites in Flavoprotein Dehydrogenases, Converting Noncovalent Flavoproteins into Covalently Flavinylated Proteins, Complexities of Riboflavin Biosynthesis, Reactions of Riboflavin Catabolism, and much more.Additional sections cover Ferredoxin-dependent thioredoxin reductase, Thermophilic Methylenetetrahydrof... Reductases, Ion-Pumping NADH:Quinone Oxidoreductase, Loading E. coli Dihydroorotate Dehydrogenase with Coenzyme Q, and Single-Component Halogenases.

  • Multiple Faces of Takotsubo Syndrome

    Clinical Presentations, Mechanisms and Advanced Diagnostic Insights
    • 1 Edición
    • Riccardo Cau + 1 más
    • Inglés
    Multiple Faces of Takotsubo Syndrome: Clinical Presentations, Mechanisms and Advanced Diagnostic Insights offers a thorough review of Takotsubo syndrome and the role of advanced imaging techniques in improving diagnosis, monitoring, and management of this complex cardiac condition. The book begins with an introduction to Takotsubo syndrome, covering its historical background, prevalence, and key clinical characteristics. Subsequent chapters delve into epidemiology, risk factors, and psychological aspects, including the impact of COVID-19 and other viral infections. Then, clinical manifestations, management, prevention, and treatments are thoroughly discussed, along with complications and prognosis. The basic science section explores the pathophysiological mechanisms, the heart-brain axis, and multi-organ involvement.A significant focus throughout is placed on invasive and non-invasive imaging modalities, including angiography, echocardiography, cardiac MRI, computed tomography, and nuclear imaging. Future directions highlight emerging biomarkers and imaging techniques for personalized medicine, and real-world case studies provide practical insights for clinicians. The book offers invaluable benefits to scientists, researchers, and clinicians alike.

  • Laboratory Sleep Medicine

    Fundamentals of Sleep Technology
    • 1 Edición
    • Ravi Gupta + 2 más
    • Inglés
    Laboratory Sleep Medicine: Fundamentals of Sleep Technology, is the second of the Fundamentals of Sleep Technology series, discusses balancing the fundamentals of sleep medicine with the newest innovations in the lab. High priority is given to practices that must be followed in sleep labs to guarantee the safety of patients and workers. To make information straightforward and easy to grasp, key events in each epoch of polysomnography are showcased. This serves to walk sleep professionals cogently through the history of sleep technology advancement.Laborato... Sleep Medicine: Fundamentals of Sleep Technology is keenly aware that manual titration with PAP is the gold standard treatment for sleep apnea. However, certain patients may require oxygen treatment, which is also covered in depth. In addition, case vignettes illustrate the development of a relevant report using the following: data from a sleep diary, actigraphy, and polysomnography. How to do sleep tests in unusual situations (such as at-home sleep apnea testing and testing in an intensive care unit) are also covered.

  • Principles and Practice of Nephrocardiology

    • 1 Edición
    • Parta Hatamizadeh
    • Inglés
    Principles and Practice of Nephrocardiology provides a comprehensive introduction to the interdisciplinary subspecialty of Nephrocardiology. The book includes detailed descriptions, along with an in-depth exploration of its primary elements and topics. Coverage spans pathophysiology, epidemiology, prevention, diagnosis, prognosis, monitoring, therapy, risk factors, and the systemic diseases that involve both nephrology-related conditions and cardiovascular diseases. The book guides clinicians and general practitioners in multiple interdisciplinary specialties through diagnostic, preventive, and therapeutic approaches to a wide variety of patient populations. It also opens a myriad of new avenues for future research and guidance for approaching multiple medical topics.

  • Therapeutic Potentials of Tenofovir Alafenamide in Hepatitis B

    • 1 Edición
    • Lung-Yi Loey Mak + 1 más
    • Inglés
    Therapeutic Potentials of Tenofovir Alafenamide in Hepatitis B offers a comprehensive examination of the therapeutic potentials of Tenofovir Alafenamide (TAF) in hepatitis B, providing a succinct and up-to-date summary of all relevant evidence for this first-line oral antiviral agent. The text delves into key topics such as the pharmacological profile of TAF, its comparative efficacy against traditional antiviral agents, safety and tolerability, and the impact of TAF on drug resistance. Additionally, it explores the use of TAF in special populations, including pediatrics, the elderly, and individuals with renal impairment, as well as future directions in hepatitis B treatment strategies.Readers will discover the diverse potential applications of TAF in chronic hepatitis B, informed by valuable lessons learned from HIV treatment while also gaining insights into future therapeutic possibilities. Authored by leading experts in the field, each chapter presents focused and insightful perspectives, making this book an indispensable resource for practitioners and researchers alike. Serving as a critical resource for physicians, researchers, pharmacologists, and biomedical scientists, this book highlights the core knowledge necessary for understanding TAF and its clinical applications.

  • The Kidney

    • 1 Edición
    • Volumen 7
    • Ahmed El-Hashash + 1 más
    • Inglés
    The Kidney, Volume Seven in the Stem Cell Innovation in Health and Disease series, explores the emerging potential of stem cell therapies in treating kidney diseases. With their natural regenerative and anti-inflammatory properties, stem cells offer a promising approach to restoring essential kidney functions and mitigating damage. This volume highlights how stem cell therapies may modulate immune responses, promote tissue repair, and replace damaged kidney cells, offering hope for chronic and acute renal conditions. Key developments include the injection of mesenchymal stem cells (MSCs) into damaged kidneys where they can differentiate into kidney cell types and aid in healing.In addition, urine-derived stem cells have also shown significant potential in improving kidney function in preclinical studies. Additionally, innovative techniques like incorporating MSCs into compact dialysis machines are explored, enabling delivery of pro-repair factors directly to the kidneys during blood filtration. While there are currently no FDA-approved stem cell treatments for kidney diseases, ongoing clinical trials aim to evaluate their safety and efficacy. This volume compiles cutting-edge research, discussing various cell sources, underlying mechanisms, observed therapeutic outcomes, and the practical challenges of clinical translation. By presenting a clear picture of current advances and future directions, this book serves as a vital resource for scientists, clinicians, and health innovators seeking to harness stem cell technology in nephrology.

  • Current Approaches to Overcome Therapeutic Resistance of Leukemia

    • 1 Edición
    • Zhe-Sheng Chen + 2 más
    • Inglés
    Current Approaches to Overcome Therapeutic Resistance of Leukemia presents a comprehensive academic resource addressing the persistent challenge of treatment resistance in leukemia. It explores biological, molecular, and clinical dimensions of resistance, bridging fundamental research with therapeutic innovation. The book examines key resistance mechanisms, including genetic mutations, leukemic stem cells, and tumor microenvironment interactions, alongside emerging insights such as epigenetic regulation, metabolic reprogramming, and immune evasion. It further highlights advanced therapeutic approaches, including immunotherapy, targeted therapies, combination strategies, and AI-driven tools for drug discovery and monitoring. This volume provides students, researchers, and clinicians with foundational and integrated knowledge essential for understanding resistance biology and translating discoveries into clinical practice. It supports evidence-based decision-making and promotes the development of innovative strategies to improve patient outcomes.

  • AI and Global Health

    Unlocking Transformative Potential
    • 1 Edición
    • Adil Haider
    • Inglés
    AI and Global Health: Unlocking Transformative Potential provides a roadmap for practitioners to apply and leverage artificial intelligence to strengthen health systems using the World Health Organization's health systems approach. The book's combination of case studies and secondary research inspires the possibility of what can happen using AI in healthcare, ensuring the use of robust, scientific evidence to draw conclusions. Additionally, readers will learn from others in settings where AI has been a tool for change, providing healthcare practitioners and policymakers with what they need to think through how it can be applied in resource limited settings.The book provides a strong call to action for policymakers and healthcare leaders of governments, international organizations, and healthcare institutions to take the lead in AI implementation as a key lever for advancing global health goals through a systems approach. As AI is a rapidly evolving field with significant investment made in this industry in recent years from government and the private sector, this book articulates how this growth can be harnessed for countries that need a different approach to addressing global health problems.

  • Molecular Chaperones in Neurodegenerative Diseases

    • 1 Edición
    • Volumen 156
    • Inglés
    Molecular Chaperones in Neurodegenerative Diseases explores the roles of molecular chaperones in maintaining protein homeostasis and their involvement in the onset and progression of neurodegenerative disorders. The book highlights current research on chaperone-mediated mechanisms, disease pathology, and emerging therapeutic approaches targeting protein misfolding and aggregation.

  • Childhood Disorders of Rickets and Osteomalacia

    A Comprehensive Review
    • 1 Edición
    • Suma Uday
    • Inglés
    Childhood Disorders of Rickets: A Comprehensive Review defines the pathophysiology of rickets and the various genetic and acquired conditions that present with rickets in childhood. This comprehensive review details the various forms of rickets, the histopathology, recent advances leading to new therapeutic options in treating rickets, and the role of Vitamin D and calcium in nutritional rickets. Additionally, the authors explore future research in various areas of nutritional and non-nutritional forms of rickets.Written by global experts for clinicians and researchers treating and studying the various forms of rickets, the book will also be of interest to those working in public health and policy makers working on the prevention of nutritional rickets worldwide.

  • Operative Strategies in Pelvic Exenteration Surgery

    • 1 Edición
    • Michael E Kelly + 1 más
    • Inglés
    Operative Strategies in Pelvic Exenteration Surgery is a reference for the surgical management of Pelvic Exenteration Surgery. It covers all aspects of surgery from the colorectal, urological, gynecological, and orthopedic point of view. Coverage consolidates the research of world-leaders and includes the history of exenterative study, outlining the current state and indicating future developments. The book also discusses the current surgical operative strategies for the management of locally advanced and recurrent pelvic neoplasms with illustrations, intra-op photos, and supplementary video material.Created from the experiences of an international collaboration of surgeons, this reference is the perfect reference for surgical oncologists, colorectal, gynecology, urology, and vascular surgeons as well as any group involved in complex pelvic surgery including complex open, laparoscopic, and robotic surgery.

  • Emergent Nanotherapeutics in Diabetic Complications

    • 1 Edición
    • Awanish Kumar + 1 más
    • Inglés
    Emergent Nanotherapeutics in Diabetic Complications explores how cutting-edge nanotechnology is transforming the treatment of diabetes-related disorders beyond glycemic control. This comprehensive volume examines targeted, multifunctional nanoplatforms designed to address the wide range of comorbidities linked to diabetes, including vascular complications, metabolic dysfunctions, and impaired wound healing. Structured in five parts, the book spans from current nanoformulation strategies to emerging innovations such as CRISPR-Cas9 delivery, AI-guided nanoparticles, and 3D/4D printed nanostructures.Bridg... the gap between preclinical research and clinical application, it offers valuable guidance on stimuli-responsive systems, biocompatible materials, and regulatory pathways. This is essential resource for medical professionals, biomedical engineers, and pharmaceutical scientists seeking scalable, next-generation solutions for managing diabetic complications through nanomedicine.

  • Ethnopharmacological Strategies for Diabetes-Associated Reproductive Co-morbidities

    Evidence-Based Molecular Mechanisms and Clinical Outcomes
    • 1 Edición
    • Debidas Ghosh + 3 más
    • Inglés
    Ethnopharmacological Strategies for Diabetes-Associated Reproductive Co-morbidities: Evidence-Based Molecular Mechanisms and Clinical Outcomes is a comprehensive, interdisciplinary reference addressing the complex link between diabetes mellitus and infertility in both men and women. This edited volume synthesizes molecular insights into diabetes-induced reproductive dysfunction—such as oxidative stress, inflammation, endocrine disruption, and tissue damage—with evidence-based evaluations of medicinal plants and their bioactive phytochemicals. It bridges laboratory research and clinical trials to highlight how plant-derived compounds can regulate glycemic control, restore hormonal balance, reduce oxidative damage, and improve gametogenesis. Targeting clinicians, researchers, and postgraduate students in biomedical and pharmaceutical sciences, the book offers detailed therapeutic profiles, safety assessments, and translational applications. By consolidating fragmented knowledge, it empowers healthcare professionals and scientists to develop integrative, cost-effective strategies for managing diabetes-related infertility.

  • Brain-Computer Interfaces (BCI)

    • 1 Edición
    • Volumen 229
    • Inglés
    Vitamins and Hormones series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Biopolymers for 3D Tissue Engineering

    Processing and Applications
    • 1 Edición
    • Narendra Reddy + 1 más
    • Inglés
    Biopolymers for 3D Tissue Engineering: Processing and Applications explores the critical role of biopolymers in advancing tissue engineering and 3D cell culture—key technologies in drug discovery, personalized medicine, and disease treatment. The book provides a comprehensive overview of the structure, properties, and processability of biopolymers with a focus on innovative techniques for converting them into functional scaffolds suitable for 3D cell culture. Sections cover carbohydrates, proteins, and synthetic biopolymers in a single, authoritative source, making it invaluable for students, researchers, professionals, and industry stakeholders.As scaffolds form the foundation of these applications, current options—primarily synthetic polymers like polypropylene, polyethylene, or polystyrene, and some natural materials such as collagen and silk fibroin—are often expensive and lack optimal properties such as biocompatibility, biodegradability, and mechanical stability. This book addresses the global effort to develop next-generation scaffolds that overcome these limitations. As biopolymers offer a compelling solution, with inherent biodegradability, biocompatibility, and sustainability, this book guides on the latest technologies and innovations.

  • The Evolution of Artificial Intelligence in Healthcare and Medicine

    From Basic Methods to Clinical Practice
    • 1 Edición
    • Mario Cannataro
    • Inglés
    The Evolution of Artificial Intelligence in Healthcare and Medicine: From Basic Methods to Clinical Practice explores revolutionary technological advancements in the medical and healthcare realms due to generative AI and Deep Learning. This comprehensive guide not only explores cutting-edge technologies such as transformers and large language models for newcomers but also demystifies advanced applications like sequential decoding techniques and segmentation algorithms rarely explored in other literature. Sections cover foundational concepts and terminologies, explore deep learning and generative AI, provide AI's role in biomedical research, examine its integration into clinical practice, scrutinize its applications in public health, and discuss challenges and future prospects.This is an indispensable resource for healthcare professionals, scientists, researchers, students, and enthusiasts seeking to deepen their understanding of this rapidly evolving field.

  • Application of Python in the Healthcare Technology

    Medical Data Analysis and Developing ML/AI Models
    • 1 Edición
    • Praveen Kumar M
    • Inglés
    Application of Python in Healthcare Technology: Medical Data Analysis and Developing ML/AI Models provides comprehensive coverage of the Python programming language from a medical-based perspective. With a strong focus on utility-based learning rather than technical-based learning of Python, this title clarifies how the application of Python in the healthcare technology industry has a meaningful impact on patient care through the development of deep learning models for early prediction of diseases and the development of Clinical Decision Support System (CDS). In 13 chapters, an extensive range of topics pertaining to the intersection of Python and medical sciences is covered. Coverage defines how to set up an environment to work with python, describes Python class, methods, and functions, explains both basic and advanced statistical analysis in Python, and provides a tool to assist in the development of deep learning models such as API, Git, Github, NumPy, Pandas, and SciPy.

  • Current Advances in Cancer Stem Cells and Neoplasia Research

    • 1 Edición
    • Volumen 8
    • Hirendra Banerjee
    • Inglés
    Cancer, Volume 8 in the Stem Cell Innovation in Health and Disease series explores the rapidly evolving role of stem cells in cancer treatment. As cancer continues to impose a heavy global health burden, stem cell therapies are being recognized for their regenerative potential and ability to enhance recovery following aggressive therapies. Hematopoietic stem cell (HSC) transplantation is already a standard, FDA-approved treatment for hematologic cancers such as leukemia, myeloma, and lymphoma. These cells help regenerate healthy blood cells post-treatment. In addition, mesenchymal stem cells (MSCs) and neural stem cells (NSCs) are showing promise in preclinical models as therapeutic carriers, capable of homing to tumor sites and delivering anti-cancer agents such as nanoparticles, siRNAs, and small-molecule drugs. Recent clinical advancements include differentiation therapy, where stem cells are used to induce cancer cells to become non-cancerous. Two completed phase I clinical trials have demonstrated innovative applications: one using NSCs to convert a prodrug into a toxic compound within tumors, and another using MSCs engineered with viral enzymes to activate cytotoxic drugs directly at the tumor site. MSCs have also helped reduce graft-versus-host disease (GVHD), a major complication of stem cell transplants. This volume is divided into two main sections: understanding stem cell roles in cancer biology, and translating stem cell innovations into clinical practice. It features cutting-edge research, including organoid models, genetic editing, and iPSC technologies. Together, these insights offer a timely review of the field’s progress and its real-world potential to reshape cancer therapy.

  • Trauma During Pregnancy

    • 1 Edición
    • Jorge Hidalgo + 2 más
    • Inglés
    Surgical Care of the Critically Ill During Pregnancy, a volume in the Critical Care Obstetrics series, is a novel reference to educate physicians, nurses, and all allied healthcare personnel caring for pregnant women in all surgical aspects including trauma. The book's authors offer best practices and evidence-based material explicitly focused on the most common complications in pregnant patients that may occur to improve patient care. It not only covers critical care investigation from medical-surgical complications that any patient can present, but also how to prepare and anticipate complications in the critical care unit.

  • Pain Conditions of the Head and Face

    A Practical Guide to Diagnosis and Management
    • 1 Edición
    • Anat Galor + 1 más
    • Inglés
    Pain Conditions of the Head and Face: A Practical Guide to Diagnosis and Management provides a user-friendly guide on diagnosing and managing common head and facial pain conditions using new methods and therapies. The book contains practical information, reviewing epidemiology, presenting key features, contributing mechanisms, and including treatment algorithms for common pain conditions of the head and face. Focus is given to aspects of disease that are novel and evolving, and all conditions are discussed within the framework of the latest advances in research and patient care.Doctors seeking to ameliorate their patients’ pain from such maladies as (among many others) neuropathic ocular pain, trigeminal neuralgia, herpetic neuralgia, temporomandibular disorders, burning mouth disorder, and neuropathic ear pain will require no other book to identify their patients’ illnesses and make sure they receive the care they need.

  • Lightweight Secure and Intelligent Approaches for Medical Devices

    Trends and Future Frontiers
    • 1 Edición
    • R. Praveen + 1 más
    • Inglés
    Lightweight Secure and Intelligent Approaches for Medical Devices: Trends and Future Frontiers addresses the rapidly evolving intersection of artificial intelligence, Internet of Medical Things (IoMT), and edge computing within healthcare. This reference meets the critical demand for resource-efficient, secure, and trustworthy AI models tailored specifically for embedded medical devices operating under stringent constraints. By integrating advances in lightweight AI, medical device security, and intelligent data processing, the book fills a vital gap in current literature, offering researchers, engineers, and healthcare professionals a comprehensive resource to develop next-generation medical technologies. The book is organized into four parts, beginning with foundational concepts including the evolution of AI in healthcare devices, lightweight model design, and medical device security standards. It progresses to predictive intelligence and reliability, covering AI techniques for disease monitoring, device calibration, and personalized medicine. The security and privacy section explores network architectures, privacy-preserving AI, lightweight cryptography, and defenses against adversarial attacks. The final part presents emerging trends such as edge AI, digital twins, explainable AI, augmented and virtual reality applications, and quantum-safe security protocols. Each chapter combines theoretical insights with practical case studies and research perspectives to guide real-world deployment. Lightweight Secure and Intelligent Approaches for Medical Devices: Trends and Future Frontiers serves as an essential reference for researchers, medical device developers, cybersecurity professionals, and graduate students aiming to innovate secure and intelligent healthcare solutions in resource-constrained environments.

  • Dry Eye Disease

    A Clinical Handbook
    • 1 Edición
    • James Stuart William Wolffsohn + 2 más
    • Inglés
    Dry Eye Disease: A Clinical Handbook illuminates the translation of cutting-edge research on dry eye disease into practical situations, allowing clinical diagnosis and management of the condition using the latest evidence-based methods. It first presents research on the core pathophysiological features of dry eye disease, including tear film instability, hyperosmolarity, inflammation, and ocular surface damage. Thereafter, it champions a patient-centered approach to dry eye management, emphasizing the necessity of classifying the ocular surface disease(s) most relevant to each case. It discusses global disease distribution and the role of non-modifiable risk factors like age, sex, and ethnicity. Additionally, the book describes tools for monitoring symptoms over time and assessing subtle signs of the disease. Readers will find practical methods for improving patient outcomes both in clinical settings and at home.

  • Metabolic Reprogramming in Breast Cancer: A New Frontier in Therapy

    • 1 Edición
    • Volumen 408
    • Inglés
    Metabolic Reprogramming in Breast Cancer: A New Frontier in Therapy explores how altered metabolic pathways drive breast cancer progression, survival, and treatment resistance. The book highlights emerging insights into tumor metabolism and discusses how these discoveries may open new avenues for targeted and more effective therapies.

  • Bioinformatics Essentials II

    From Multi‑omics to AI – Methods, Workflows, and Translational Applications
    • 1 Edición
    • Syed Mudasir Ahmad + 2 más
    • Inglés
    Bioinformatics Essentials II, From Multi‑omics to AI – Methods, Workflows, and Translational Applications offers a comprehensive guide to modern bioinformatics, focusing on best-practice workflows for multi-omics data analysis and AI-assisted discovery. Designed for learners and early-career researchers, it bridges foundational knowledge with cutting-edge applications. The book covers experimental design, sequencing technologies, and core omics workflows including transcriptomics, proteomics, metabolomics, and epigenomics. Advanced chapters explore single-cell and spatial omics, multi-omics integration, AI/ML applications, and environmental bioinformatics.Each chapter includes learning objectives, worked examples, toolbox comparisons, and reproducible code. This resource empowers students, faculty, and applied researchers to confidently analyze complex datasets and translate findings into agriculture, health, and environmental solutions. Its modular structure and companion website enhance usability in both coursework and independent study.

  • Biofeedback and Pain Management

    A Clinical Guide
    • 1 Edición
    • Anu Kotay
    • Inglés
    Biofeedback and Pain Management: A Clinical Guide provides a detailed understanding of the psychophysiology of chronic pain, biofeedback treatments, the realities of living life with chronic pain limitations, and the role of pain in our lives and society. The book covers evidence on the effective uses of biofeedback interventions for pain management, including protocols, as well as case-based examples and strategies practitioners can use in real-life settings. Sections define biofeedback, including illustrations that depict how biofeedback is a useful part of any pain management treatment plan, cover procedures based on evidence and case examples, and present the social context of chronic pain.

  • Fetal Metabolic Programming in Obesity and Diabetes

    From Mechanisms to Preventive Therapy
    • 1 Edición
    • Luis Sobrevia
    • Inglés
    Fetal Metabolic Programming in Obesity and Diabetes: From Mechanisms to Preventive Therapy describes the consequences of cellular and molecular aspects of maternal obesity (before and during pregnancy), diabetes mellitus (pregestational and gestational), and gestational diabesity (i.e., women with pre-pregnancy obesity that developed GDM). The book covers the clinical aspects of mothers and children and the protocols for treating these diseases during pregnancy. Since the patients' clinical information correlates with metabolic parameters at a cellular and systemic level, it covers several pieces of evidence, addressing the pathophysiology of obesity and diabetes in pregnancy. This is an important resource for health professionals, researchers, and postdocs in obesity diabetes, as well as public health, physiology, biochemistry, cell biology, cell physiology, cell metabolism, and clinical and translational medicine.

  • Biomaterials in Cancer Therapy

    Innovations and Applications
    • 1 Edición
    • Alok Raghav
    • Inglés
    Biomaterials in Cancer Therapy: Innovations and Applications explores the critical role of functional biomaterials in addressing one of today’s most pressing health challenges—cancer. Despite advancements in therapies, cancer continues to claim millions of lives annually, necessitating innovative approaches that integrate engineering and pharmaceutical sciences. This book highlights the potential of engineered biomaterials to enhance drug delivery, minimize side effects, and promote tissue regeneration, ultimately improving patient outcomes. The content examines cutting-edge innovations in functional biomaterials, including their applications in targeted drug delivery and immunotherapy, while emphasizing the role of nanotechnology in developing effective cancer theranostics with minimal toxicity. Targeted at academicians, physicians, and industry professionals, this book serves as a vital resource for understanding the transformative potential of functional biomaterials in oncology. By addressing real-world challenges and incorporating diverse perspectives, it inspires innovative solutions that enhance global healthcare outcomes for cancer patients.

  • Plant Development

    • 1 Edición
    • Volumen 172
    • Inglés
    Plant Development provides an overview of the fundamental processes that govern the growth, differentiation, and organization of plants throughout their life cycle. The book explores key developmental stages, from embryogenesis and seed germination to organ formation, flowering, and senescence, highlighting the genetic, molecular, cellular, and environmental factors that regulate these events. By integrating classical concepts with modern advances in developmental biology, the volume offers valuable insight into how plants establish form, adapt to their surroundings, and coordinate growth in response to internal and external signals. It serves as a useful resource for researchers, students, and professionals interested in plant biology, developmental mechanisms, and related fields.

  • Health Impacts of Climate Change

    A Global Perspective
    • 1 Edición
    • Mohammad Hadi Dehghani + 2 más
    • Inglés
    Health Impacts of Climate Change: A Global Perspective confronts the most urgent reality of our time: the climate crisis is, at its core, a health crisis. Drawing from the latest research in climate science, public health, and policy, this book offers a comprehensive, interdisciplinary look at how global warming is already endangering lives—and what can be done to protect them. Readers will gain a deep understanding of direct health threats like heatstroke, air pollution, and disaster-related trauma, as well as the less visible dangers: rising zoonotic diseases, crop failures leading to malnutrition, and mental health challenges driven by climate-induced displacement.What sets this book apart is its unwavering focus on equity. It explores how climate change disproportionately impacts the most vulnerable—low-incom... communities, people in the Global South, and marginalized groups—who contribute the least to global emissions but bear the brunt of the damage. Through case studies, personal narratives, and policy analysis, the book amplifies frontline experiences and calls for climate justice as an essential part of any effective health response. From practical strategies for healthcare professionals to frameworks for policymakers, this book empowers a wide range of readers—from students and researchers to community leaders and concerned citizens.

  • Human Reproduction

    From basics to Biotechnology
    • 1 Edición
    • Marc yeste
    • Inglés
    Human Reproduction: From Basics to Biotechnology is a complete reference for anyone in the field of life, health, and biomedical sciences. The book provides an overview of basics in human reproduction to advanced knowledge of the field, including some evidence from other mammalian species that complement our current knowledge on the anatomy and physiology of the male and female reproductive tract and gametes. This resource covers the most used assisted reproductive techniques and technical advances, human reproduction and infertility disorders, their diagnosis and available treatment options.

  • Cell Death Part H

    • 1 Edición
    • Volumen 215
    • Inglés
    Cell Death Part H presents current methods and experimental approaches for studying the mechanisms, regulation, and biological significance of cell death. The volume covers advanced protocols and model systems used to investigate diverse cell death pathways in health and disease, making it a valuable resource for researchers in cell biology, molecular biology, and biomedical science.

  • Advances in Medical Simulation

    Techniques, Applications and Innovations
    • 1 Edición
    • Noor Zaman Jhanjhi + 2 más
    • Inglés
    Advances in Medical Simulation: Techniques, Applications, and Innovations explores cutting-edge developments in medical simulation, focusing on its transformative role in medical education, training, and patient care. The book examines various simulation techniques, including virtual and augmented reality, high-fidelity mannequins, and task trainers, showcasing their applications in surgical training, clinical diagnostics, and emergency response. Sections provide an in-depth discussion of the challenges and future directions in medical simulation, highlighting innovations such as robotics and artificial intelligence. By addressing gaps in existing literature, this book offers a comprehensive understanding of how advanced simulation techniques can enhance healthcare professionals' skills and competencies.For the academic audience, this book serves as a vital resource that bridges research and practical applications in clinical settings. It identifies trends and opportunities for future innovation, ultimately aiming to reduce medical errors and improve patient safety through effective simulation-based practices.

  • Nanotechnology in Brain Tumor Treatment

    Unveiling Molecular Mechanisms and Pioneering Therapies
    • 1 Edición
    • Arun Kumar Singh + 4 más
    • Inglés
    Nanobiotechnology in Brain Tumor Treatment: Unveiling Molecular Mechanisms and Pioneering Therapies is a groundbreaking resource that addresses the formidable challenges posed by brain tumors in oncology. This comprehensive book explores the etiology, symptoms, diagnosis, and treatment options for brain tumors, with a particular focus on the revolutionary impact of nanobiotechnology. By integrating cutting-edge research on nanotechnology with practical applications in neuro-oncology, this book offers a unique perspective on enhancing patient outcomes and advancing brain cancer treatment strategies.By offering a comprehensive overview of nanobiotechnology in brain tumor treatment, this resource serves as a vital tool for those involved in the research, diagnosis, and treatment of brain cancers, paving the way for innovative and personalized therapeutic approaches.

  • Space Physiology

    From Earth to Space and Back Again
    • 1 Edición
    • Alan Hargens
    • Inglés
    Space Physiology: From Earth to Space and Back Again provides readers with new and authoritative information about current and important topics related to risks and their countermeasures in space.This book covers translation of Earth-based physiology to astronaut health and Earth applications of space research. Topics include adaptations of various systems to space, including bone, microcirculation, microcirculation, skeletal and smooth muscles, headward fluid shifts, vision as well as integrated countermeasures to maintain well-being and health in space.This is a volume in Elsevier’s series Hot Topics in Physiology, published in association with the International Union of Physiological Sciences. It is an ideal reference for academics and researchers (space physiology and medicine, space radiation, rehabilitation medicine, exercise, wound healing, biochemistry and cell biology, molecular biology) at undergraduate, masters, PhD, and Post-Doc levels.

  • Essentials of Medical Coordination in Complex Humanitarian Emergencies

    • 1 Edición
    • Joanna Kotcher
    • Inglés
    Essentials of Public Health and Medical Coordination in Complex Humanitarian Emergencies provides a practical overview for health coordinators in assessing, coordinating, and implementing medical and public health responses in disaster and conflict environments. The book aims to achieve this in two parts. Part one covers foundational information such as the role of the coordinator; project assessment and start-up; standards, protocols, and guidelines; project strategy and accountability; and basic epidemiological measurements and tools. Part two goes on to discuss the implementation of programs and services like nutrition, mental health and psychosocial support (MHPSS), management of chronic disease, community health promotion, sexual and reproductive health, health information systems and disease surveillance. A health coordinator in the field is required to quickly assess the needs of a population in a humanitarian emergency, initiate start-up procedures, and coordinate the response over a period of months or longer. The efficiency and effectiveness of this process depends on the experience, knowledge, and skills of the coordinator, Essentials of Public Health and Medical Coordination in Complex Humanitarian Emergencies is a resource for those in the medical, public health, and international humanitarian aid sectors who care about the health of populations at risk and is written by an author who has coordinated emergency response in conflict environments in Kosovo, Central Asia (Tajikistan), Afghanistan, Darfur, Gaza and the OPT, Somaliland, Syria, and Iraq.

  • Advances in Design of Microbial Cell Factories

    • 1 Edición
    • Dibyajit Lahiri
    • Inglés
    Advances in Design of Microbial Cell Factories presents a comprehensive overview of the latest innovations in engineering microbial platforms for sustainable production of biochemicals, biofuels, pharmaceuticals, and industrial enzymes.The book opens with an introduction and historical overview of microbial cell factories, followed by a wide spectrum of topics including omics-driven design and engineering of microbial cell factories, metabolic flux analysis, genome-scale metabolic modeling, modular pathway engineering, biosensors, adaptive laboratory evolution, protein engineering and enzyme optimization in microbial hosts. The latest developments in designing bacterial, yeast, mold and microalagae cell factories are covered, as well as current challenges to be considered in scale-up of microbial cell factories. Chapters are supported by real-world case studies that demonstrate translation from laboratory research to industrial-scale applications across a diverse range of sectors.This reference consolidates foundational knowledge with emerging technologies, equipping researchers, graduate students, and industry professionals with practical insights to accelerate their own development of microbial platforms.

  • Advanced Nanofiber Technology in Cancer Management

    • 1 Edición
    • Goutam Rath + 2 más
    • Inglés
    Advanced Nanofiber Technology in Cancer Management presents a comprehensive exploration of nanofiber-based systems for cancer therapy and diagnostics. It bridges pharmaceutical sciences, nanotechnology, and oncology to address the challenges of targeted drug delivery and systemic toxicity. The book covers biopolymer, peptide, carbon, and metal nanofibers, detailing their fabrication, characterization, and application in chemotherapy, immunotherapy, gene therapy, and photothermal treatment. It also explores diagnostic innovations such as biosensors and imaging-guided systems, alongside AI and 3D printing in nanofiber development. This volume benefits researchers, clinicians, and pharmaceutical developers by offering translational insights, regulatory perspectives, and real-world case studies. It supports informed decision-making in cancer management and product development.

  • Emerging Technologies in Bioengineering for Oncology

    Fundamentals, Research, and Future Prospects
    • 1 Edición
    • Saikat Das + 2 más
    • Inglés
    Emerging Technologies in Bioengineering for Oncology: Fundamentals, Research, and Future Prospects explores the integration of engineering, biology, and medicine to tackle challenges in developing innovative tools for cancer diagnosis and treatment. This comprehensive resource addresses the evolving landscape of bioengineering in oncology, highlighting the intersection of various disciplines to drive advancements in diagnostic and therapeutic approaches. The book explores a range of cutting-edge technologies such as lab-on-chip devices, wearable biosensors, 3D bioprinting, and targeted nanomedicine, offering promising avenues for enhanced diagnostic precision, treatment effectiveness, and personalized healthcare.Geared towards medical students and professionals, the book provides detailed insights into the latest developments, practical applications, and future research directions in the field. By offering a deep dive into the realm of bioengineering for oncology, it serves as a valuable asset for those seeking to advance cancer care through interdisciplinary collaboration and innovation.

  • Endoscopic Ultrasound in Pancreatic Diseases

    Best Practices and Recent Innovations in Technology and Techniques
    • 1 Edición
    • Masayuki Kitano
    • Inglés
    In Endoscopic Ultrasound in Pancreatic Diseases: Best Practices and Recent Innovations in Technology and Techniques, leading experts share their insights, best practices, and the latest technological innovations revolutionizing the approach to pancreatic diseases. This practical reference provides step-by-step guidance, case presentations, and detailed images and procedures on advanced techniques in diagnosis and treatment with endoscopic ultrasound for pancreatic diseases.Organized into four sections, this book reviews the latest advances in endoscopic ultrasound equipment, techniques, complications, scanning methods, microbubbles and contrast harmonic imaging, elastography, fine needle tissue acquisition, and classification and safety management of interventional endoscopic ultrasound. Tumor detection, characterization, and diagnosis are reviewed, and pancreatic diseases treatment and intervention methods are covered extensively. The book concludes with the examination of groundbreaking methods and discussion of education and future directions. Endoscopic Ultrasound in Pancreatic Diseases: Best Practices and Recent Innovations in Technology and Techniques fully equips endoscopists with the most recent developments in endoscopic ultrasound and is a vital resource for navigating the evolving landscape, enabling practitioners to excel in advanced clinical practices and contribute to the field’s growth.

  • Lifestyle Medicine

    Lifestyle, the Environment and Preventive Medicine in Health and Disease
    • 4 Edición
    • Michael Sagner
    • Inglés
    Lifestyle Medicine: Lifestyle, the Environment and Preventive Medicine in Health and Disease, Fourth Edition aims to reduce the burden of chronic diseases by harnessing technology and providing a better understanding of environment-biology interactions, evidence-based interventions, and the underlying mechanisms of chronic diseases. This new edition is greatly expanded to cover major chronic diseases as well as infectious diseases. Led by top experts in the field, the editors provide a framework to promote and facilitate multi-stakeholder collaboration with an orchestrated common language and an integrated care model to increase the population’s heath span.The book provides the latest research updates on the pathophysiology of preventable diseases, Clinical updates on interventions for practice, and Public health updates on Precision Medicine / Systems Biology approaches to prevention for clinicians and Interdisciplinary aspects for allied health professionals. It is essential to healthcare professionals who want to: understand the potential of preventing diseases; understand how to maintain health and well-being; understand the implications of preventable diseases for society and individuals; and understand lifestyle aspects in the prevention and treatment of diseases.

  • An Essential Guide to Radiation Dosimetry for Medical Applications

    Principles, Technologies, and Clinical Applications
    • 1 Edición
    • Jayachandran Venkatesan + 1 más
    • Inglés
    An Essential Guide to Radiation Dosimetry for Medical Applications: Principles, Technologies, and Clinical Applications provides a comprehensive overview of the fundamental concepts, advanced methodologies, and emerging technologies in radiation dosimetry. This book serves as an essential resource for researchers, clinicians, and students involved in cancer research, bioinformatics, medical physics, radiology, material scientists and radiation therapy, offering in-depth insights into both theoretical principles and practical applications. The content covers core topics such as radiation interactions, dosimetry materials, and simulation techniques, alongside clinical and diagnostic applications.In addition, it also explores innovative approaches like artificial intelligence, nanodosimetry, and quality assurance, ensuring readers stay current with technological advancements. This book benefits the academic audience by enhancing their knowledge of dosimetry science and fostering the development of safer, more effective radiation practices. It supports education, research, and clinical decision-making, ultimately advancing the field of radiation physics and improving patient outcomes.

  • Artificial Intelligence Based Primary Care

    Artificial Intelligence and Human Cognition in General Practice and Family Medicine
    • 1 Edición
    • Anthony C. Chang + 5 más
    • Inglés
    Artificial Intelligence Based Primary Care: Artificial Intelligence and Human Cognition in General Practice and Family Medicine provides a comprehensive look into the integration of artificial intelligence within primary care. This book aims to bridge the gap between data scientists and primary care clinicians by presenting potential AI applications, implementation challenges, and real-world clinical scenarios in an accessible manner. Comprised of 5 sections and 20 chapters, it offers both theoretical insights and practical guidance for family medicine practitioners.Additi... the book includes a chapter dedicated to a day in the life of a General Practitioner, showcasing the practical impact of AI. It also features an extra compendium listing the Top 100 articles and best books on Artificial Intelligence. This resource is invaluable for academics, researchers, and clinicians eager to expand their knowledge in this emerging field.

  • Leveraging AI and ML in Cardiovascular Diagnosis and Management

    • 1 Edición
    • Rosaline Mishra + 3 más
    • Inglés
    Leveraging AI and ML in Cardiovascular Diagnosis and Management examines how artificial intelligence and machine learning transform cardiovascular care. It gathers chapters from leading researchers to bridge clinical practice with cutting-edge analytics, imaging, and decision support. The volume details core topics across the field, including fundamentals of AI/ML, AI-driven cardiovascular imaging, predictive analytics for risk stratification, heart failure management, arrhythmia detection, wearable-enabled monitoring, and the integration of multi-omics with clinical data. It also addresses neurocardiology, clinical decision support systems, ethics, and regulatory considerations, all framed for cardiovascular scientists and clinicians. For academics, clinicians, and educators, the book offers actionable workflows, a cohesive framework for translating AI and ML advances into improved diagnosis, treatment personalization, and patient outcomes across diverse populations.

  • Robotics and Artificial Intelligence in Neuromuscular Performance

    Assessment, Training, Injury Prevention, and Return to Play in Athletes
    • 1 Edición
    • Wissem Dhahbi + 1 más
    • Inglés
    Athletic performance depends on technologies that can measure, model, and guide neuromuscular function across the complete athlete lifecycle. Robotics and Artificial Intelligence in Neuromuscular Performance provides an evidence-based framework for applying robotics, artificial intelligence, computer vision, wearable sensing, virtual reality, and biofeedback to assessment, training, injury prevention, rehabilitation, and return-to-play decision-making. Organized across 18 chapters, the book connects neuromuscular physiology with intelligent athlete systems, progressing from foundational concepts in computational biomechanics and robotic dynamometry to applied protocols for training load management, injury risk prediction, exoskeletal resistance training, smart rehabilitation, and AI-enhanced return-to-play clearance. Written for sports scientists, clinicians, physiotherapists, athletic trainers, strength and conditioning professionals, biomechanics researchers, and technology developers, it equips readers to evaluate rapidly expanding sports technologies with scientific rigor rather than assuming that innovation is inherently beneficial. Each chapter addresses validation status, measurement error, algorithmic limitations, data governance, and ethical risk, translating research evidence into criteria practitioners can apply directly. The AICICA framework, six implementation checklists, and integrated case studies extend the book beyond synthesis into practical guidance for responsible technology adoption in elite, clinical, and research settings.

  • Hereditary Syndromes Associated with Endocrine Tumors

    • 1 Edición
    • Volumen 134
    • Inglés
    Volume 134, Hereditary Syndromes Associated with Endocrine Tumors, provides a comprehensive and up-to-date overview of the genetic, molecular, clinical, diagnostic, and therapeutic aspects of inherited endocrine neoplasia syndromes. Over the past two decades, remarkable advances in genomics, molecular diagnostics, and precision medicine have transformed the understanding and management of hereditary endocrine tumor syndromes, enabling earlier diagnosis, individualized surveillance strategies, targeted therapies, and improved patient outcomes. This volume brings together contributions from internationally recognized experts to review the current state of knowledge on both well-established and emerging hereditary syndromes affecting the endocrine system. The chapters cover the genetic basis, genotype–phenotype correlations, clinical manifestations, screening recommendations, multidisciplinary management, and future therapeutic perspectives for syndromes predisposing to tumors of the adrenal glands, pituitary, thyroid, parathyroid, pancreas, and neuroendocrine tissues. Special emphasis is placed on recent discoveries in cancer predisposition genes, advances in molecular pathology, the integration of next-generation sequencing into clinical practice, and the implications of hereditary cancer syndromes for patients and their families.

  • Advanced Ultrasound with Imaging Correlations of Diffuse Liver Diseases

    • 1 Edición
    • Riccardo De Robertis
    • Inglés
    Advanced Ultrasound with Imaging Correlations of Diffuse Liver Diseases addresses the critical need for detailed comparisons between advanced ultrasound (US) techniques and CT/MRI findings in the evaluation of liver diseases. While many books exist, few provide the in-depth analysis and practical guidelines necessary for accurate diagnosis and effective treatment planning. This book fills that gap, offering a multiparametric approach to the assessment of fibrotic and steatotic liver diseases. Inside, readers will find essential topics such as indications for liver US in diffuse liver diseases, advanced Ultrasound techniques for assessing liver fibrosis and steatosis, and the correlation between US, CT, and MRI findings.Key chapters cover the basics of liver ultrasound, conventional Doppler and microvascular flow imaging, ultrasound elastography, and the quantification of liver steatosis. Additionally, the book explores cutting-edge topics like artificial intelligence in liver ultrasound and the application of US in pediatric patients. Contributions from leading experts in the field ensure that each chapter provides valuable insights and practical advice. This is an indispensable resource for scientists, researchers, and clinicians alike. It offers clear guidelines on performing liver ultrasounds, understanding and interpreting results, and making informed comparisons with CT and MRI findings.

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