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Elsevier

Libros en Neurología

  • Central Nervous System Viral Infections

    • 1 Edición
    • Karen L. Roos + 1 más
    • Inglés
    Central nervous system viral infections pose one of the greatest threats to humanity, as evidenced by recent history with SARS-CoV-2 (COVID 19), HIV, and others. Understanding their effects, therapeutics, and prevention are a top priority for all. "Central Nervous System Viral Infections" reviews the mechanisms of viral infections, current viruses of interest, diagnosis, course, and therapeutics, as well as prevention. Post infection syndromes and complications are also reviewed. Coverage includes Covid, HIV, Zika, EBOLA, Marburg, Herpes, Measles, Mumps, Polio, and more.

  • Primer on Cerebrovascular Research

    • 1 Edición
    • Dong-Eog Kim + 3 más
    • Inglés
    Primer on Cerebrovascular Research provides both clinical and basic cerebrovascular knowledge that is required for physicians, vascular researchers, biomedical students, and trainees to understand or conduct evidence-based clinical practice and cutting-edge experimental research. This book outlines how to a design experimental cerebrovascular research in the context of clinical relevance, conduct the study using proper methods, analyze the data accurately, and make conclusions in an unbiased and statistically correct way. Chapters will include representative examples and experimental protocols.

  • Neurosurgical Neuropsychology

    The Practical Application of Neuropsychology in the Neurosurgical Practice
    • 2 Edición
    • Caleb M. Pearson + 2 más
    • Inglés
    The second edition of Neurosurgical Neuropsychology: The Practical Application of Neuropsychology in the Neurosurgical Practice offers an in-depth review of the critical role neuropsychology plays in neurosurgical settings. This comprehensive resource covers essential preoperative techniques, including advanced functional neuroimaging methods such as fMRI and connectivity-based imaging, alongside traditional approaches like neurocognitive testing and the Wada procedure. This book highlights the significant contributions of neuropsychologists to the neurosurgical team, emphasizing their value in managing diverse patient populations, from candidates for Deep Brain Stimulation to those undergoing adult and pediatric epilepsy surgeries and neuro-oncology interventions. New chapters in this edition address contemporary topics such as the cognitive impact of epilepsy and epilepsy surgery, concussion, neuroplasticity, and the future role of artificial intelligence in neurosurgery. By updating existing content and incorporating fresh insights, this book serves as an essential guide for neurosurgeons, neuropsychologists, neuro-oncologists, epileptologists, and general neurologists who wish to enhance their understanding of neuropsychology's application in both preoperative and postoperative care.

  • The Alzheimer’s Spectrum: From Neural Stress to AI-Driven Care

    • 1 Edición
    • Volumen 192
    • Inglés
    The Alzheimer’s Spectrum: From Neural Stress to AI-Driven Care, published as Volume 192 of the serial International Review of Neurobiology, provides a comprehensive and multidisciplinary examination of Alzheimer’s disease (AD) across its biological, psychological, and technological dimensions. This volume integrates current research on neuropsychiatric factors such as depression, stress, and anxiety with advances in neuroanatomy, systems neuroscience, and emerging AI-driven diagnostic and therapeutic approaches. Chapters explore key brain regions and circuits implicated in AD—including the thalamus, prefrontal cortex, hippocampus, and memory-emotion networks—while also addressing comorbidities, extracellular vesicles as biomarkers, and innovative treatment strategies. The inclusion of computational approaches, model organisms, and novel therapeutic avenues reflects a strong translational focus, bridging mechanistic understanding with clinical and digital health applications. Collectively, this volume serves as an authoritative resource for understanding the Alzheimer’s continuum from early cognitive impairment to advanced disease and care optimisation.

  • Complications in Neuroanesthesia

    • 2 Edición
    • Hemanshu Prabhakar
    • Inglés
    Complications in Neuroanesthesia, Second Edition offers an extensive examination of the complications associated with neuroanesthesia practice, emphasizing both new and existing challenges in the field. This updated edition introduces critical topics such as locked-in syndrome, cerebellar mutism syndrome, delirium, awareness, memory loss, perioperative stroke, and coma, alongside established complications like brain herniation, hydrocephalus, and seizures. Each complication is meticulously examined in separate chapters, detailing the pathophysiology, mechanisms, diagnosis, treatment, and prevention strategies. This book also addresses cardiovascular issues, including stunned myocardium, as well as fluid and electrolyte disturbances like glucose dysregulation and conditions like post-dural puncture headache, malignant hyperthermia and reperfusion injury. Written in an accessible format for quick navigation, this resource provides invaluable insights into the perioperative management of neurosurgical and neurologic patients. This book is a practical tool for trainees, clinicians, and researchers in anesthesia, neuroanesthesia, neurosurgery, neurocritical care, and neurology. By highlighting preventable mishaps, this edition aims to enhance the safety and efficacy of neuroanesthesia and neurocritical care practice.

  • Nanomedicine for Neurological Disorders

    Design, Delivery, and Clinical Perspectives
    • 1 Edición
    • Saman Fatima + 4 más
    • Inglés
    Nanomedicine for Neurological Disorders: Design, Delivery, and Clinical Perspectives addresses the urgent need for innovative solutions in treating complex neurological and neurodegenerative diseases. As the global burden of conditions such as Alzheimer's, Parkinson's, multiple sclerosis, and brain tumors continues to rise, the scientific community faces the critical challenge of safely and effectively delivering therapeutics across the blood-brain barrier. This reference meets the needs of neuroscientists, clinicians, pharmaceutical scientists, and biomedical engineers seeking advanced strategies and translational insights in neuro-nanomedicine. The contents are structured to provide a comprehensive, interdisciplinary exploration of the field. Chapters cover the anatomy and connectivity of the human brain, the global burden and mechanisms of neurological disorders, conventional and nanomedicine-based drug delivery systems, and the intricacies of the blood-brain barrier. Readers will benefit from detailed analyses of nanocarrier engineering, stability, analytical techniques, toxicological safety, regulatory challenges, and artificial intelligence-driven drug design. Real-world case studies, clinical trial data, and future outlooks are presented alongside ethical and patient-centric considerations, ensuring a holistic perspective on the evolving landscape of neuro-nanomedicine. Nanomedicine for Neurological Disorders delivers essential benefits by bridging the gap between laboratory innovation and clinical practice. It equips readers with practical knowledge, foundational advances, and visionary insights to inspire new research directions, inform better decision-making, and accelerate the development of safer, more precise treatments for brain-related disorders. This reference is an indispensable resource for researchers, clinicians, and innovators at the forefront of neurological therapeutics.

  • Blood-Based Biomarkers for Alzheimer's and Parkinson's Disease – Part A

    • 1 Edición
    • Volumen 191
    • Inglés
    Blood-Based Biomarkers for Alzheimer’s and Parkinson’s Disease, Volume 191 in the International Review of Neurobiology series, presents current advances and comprehensive reviews on the development and application of circulating biomarkers in neurodegenerative disorders. It brings together contributions from an international panel, highlighting emerging strategies for early detection, diagnosis, and monitoring of Alzheimer’s and Parkinson’s diseases. Chapters explore a wide range of topics, including the Diagnostic Potential of Exosomes in Neurodegenerative Diseases and Cancer, Blood Biomarkers of Oxidative Stress and Mitochondrial Dysfunction in Alzheimer’s and Parkinson’s Diseases, GFAP and the Genetic Code of Astrocyte Activation in Alzheimer’s Disease, and much more.Additional chapters cover Blood-Based Emerging Biomarkers in Early Detection and Diagnosis of Alzheimer’s Disease, Advances in Nanomaterial-Based Biomarker Detection for Neurodegenerative Diseases, Blood-Based Biomarkers in Alzheimer’s and Parkinson’s Disease: From Molecular Pathology to Therapeutic Potential, Blood-Based Biomarkers and Their Role in AD/PD Diagnosis, The Emerging Landscape of Circulatory Biomarkers in Alzheimer’s Disease, Biofluid-Based Biosensors, Biomarkers of Vascular Dementia and Alzheimer’s Disease, Silent Clues in Blood: Proteomic Approach for Alzheimer’s Disease, and more.

  • Neurogynecology and Associated Neurological Disorders

    • 1 Edición
    • Vishal K. Chavda + 2 más
    • Inglés
    Neurogynecology and Associated Neurological Disorders addresses the emerging interdisciplinary field linking neurology and gynecology, focusing on how neurological disorders impact female reproductive health throughout the lifespan. The book covers foundational neuroanatomy, hormonal influences on neurological function, and specific disorders including headaches, epilepsy, pelvic neuropathies, and mental health conditions related to reproductive stages. It includes clinical guidelines, case studies, diagnostic tools, and treatment protocols tailored to hormonal phases and life stages. The integration of neurobiological mechanisms with gynecological considerations offers readers a robust framework for interdisciplinary collaboration.Reader... will find this to be a great reference that responds to the growing clinical need for integrated understanding and management of conditions such as menstrual migraines, pregnancy-related neuropathies, and menopausal neurological changes.

  • Diagnostic Application of Blood-based Biomarkers for Neurodegenerative Diseases

    • 1 Edición
    • Meenakshi Dhanawat + 4 más
    • Inglés
    Diagnostic Application of Blood-based Biomarkers for Neurodegenerative Diseases is a comprehensive exploration of the pivotal role blood-based biomarkers play in diagnosing and managing neurological disorders. This comprehensive guide emphasizes the need for early detection and intervention in conditions such as Alzheimer’s disease, Parkinson’s disease, and neuroinflammation. Each chapter delves into specific biomarkers, including glial fibrillary acidic protein and neurofilaments, elucidating their diagnostic potential. This book highlights recent advancements in the application of blood biomarkers across various neurodegenerative diseases, underscoring the integration of artificial intelligence in biomarker discovery. By bridging research and clinical practice, it serves as an essential resource for professionals in diagnostic sciences, pharmaceutical research, and clinical pharmacology. Ultimately, this volume aims to reshape the landscape of early diagnosis, offering insights that promise to enhance personalized treatment strategies and improve patient outcomes in the fight against debilitating neurological disorders.

  • International Review of Neurobiology

    • 1 Edición
    • Volumen 190
    • Inglés
    International Review of Neurobiology, Volume 190 highlights new advances in the field, with this volume presenting an in-depth chapter on imaging the glymphatic system in Huntington’s disease. This contribution explores the benefits of multimodal imaging approaches and their clinical implications, offering insights into disease mechanisms and potential diagnostic strategies.This volume provides a focused and up-to-date perspective on neurobiological research, serving as a valuable resource for researchers and clinicians interested in neurodegenerative disorders and advanced imaging techniques.

  • Motor Control Methods and Clinical Applications

    • 1 Edición
    • Robert Chen + 1 más
    • Inglés
    Motor Control Methods and Clinical Applications provides a detailed review on the use of non-invasive brain stimulation to study motor control. Split into two distinct parts, this new volume covers the latest research in motor control, including real examples of these methods in a clinical setting. The first part covers advanced methods such as transcranial magnetic, electrical and ultrasound stimulation, long latency, spinal reflexes, multichannel EMG, and EEG-EMG analyses that can be used to examine and modulate the motor system. The second part of the book addresses the clinical applications of these methods.

  • Practice of Neurocritical Care in Resource Limited Countries

    • 1 Edición
    • Hemanshu Prabhakar + 2 más
    • Inglés
    Practice of Neurocritical Care in Resource Limited Countries offers a comprehensive examination of the unique challenges and practical strategies for delivering neurocritical care in low- and middle-income countries (LMICs). As the prevalence of neurological emergencies continues to rise in these regions, this book addresses the critical need for effective management in resource constrained environments. It begins by exploring the landscape of neurocritical care, including common neurological emergencies and their epidemiology in LMICs. The content outlines foundational principles of patient assessment and monitoring, as well as advanced management strategies for conditions such as traumatic brain injury, stroke, and spinal cord injury. Special attention is given to the nuances of caring for diverse patient populations, including pediatric and geriatric patients. Additionally, this book highlights the essential role of pain management, and nutritional support, in neurocritical settings. With contributions from experts across various LMICs, this resource emphasizes innovative approaches to training and capacity building, empowering healthcare professionals to provide high-quality neurocritical care despite the challenges of limited resources. This book is an invaluable tool for clinicians and educators dedicated to improving outcomes for neurologically ill patients in lesser-resourced healthcare systems.

  • Cranial Nerve Compression Syndromes

    A Multidisciplinary Guide to Management
    • 1 Edición
    • Florian Roser + 1 más
    • Inglés
    Cranial Nerve Compression Syndromes: A Multidisciplinary Guide to Management is a comprehensive volume exploring the entire pathophysiology of cranial nerve pathologies, from diagnosis to treatment options. Following a multidisciplinary approach, this volume integrates perspectives from neurosurgery, neurology, radiology, and pain management from experts in the field. An ideal resource for clinicians and researchers, this volume discusses the latest research on multi-modality, collaborative, and cutting-edge treatment options, with advanced surgical techniques, including microvascular decompression and endoscopic procedures with clear guidance.

  • Epigenetic Mechanisms in Brain Physiology and Disorders

    • 1 Edición
    • Moshe Szyf + 1 más
    • Inglés
    Epigenetic Mechanisms in Brain Physiology and Disorders provides a comprehensive summary of epigenetic mechanisms in brain development, from embryogenesis to aging, brain physiology and pathology. It discusses the role DNA methylation plays in regulating genomic functions, which in turn guide brain function. The book explores the epigenetic role in cell type differentiation, epigenetic processes in memory, learning, and neuronal functioning, the role of DNA methylation and other epigenetic mechanisms in sleep, feeding and metabolic control, sex, temperature regulation, and cardiovascular and blood pressure regulation. It further explores the role of epigenetic processes in neuropsychiatry disorders, neurological disease and behavioral disorders, as well as epigenetic diagnostics and therapeutics.

  • Real-World Research to Improve Dementia Care

    Embedding Pragmatic Trials of Non-Drug Interventions
    • 1 Edición
    • Jill Harrison + 1 más
    • Inglés
    Real-World Research to Improve Dementia Care: Embedding Pragmatic Trials of Non-Drug Interventions addresses the urgent need for effective care strategies for the over 50 million individuals living with Alzheimer's disease and related dementias. This insightful book introduces embedded, pragmatic trials as a way to bridge the gap between clinical research and everyday practice, emphasizing collaboration among healthcare systems, researchers, and communities. Through a series of chapters, the book explores partnership strategies, ethical considerations, and the selection of meaningful outcome measures, all aimed at enhancing dementia care. The authors present case studies that showcase successful interventions and innovative practices across care settings.By highlighting both the challenges and solutions in dementia care, this book serves as a vital resource for healthcare professionals and researchers. It advocates for a compassionate approach that values the voices of individuals living with dementia, ultimately aiming to improve their quality of life.

  • Advanced and Integrative Therapeutic Strategies in Parkinson’s Disease Management

    • 1 Edición
    • Wael Mohamed
    • Inglés
    Advanced and Integrative Therapeutic Strategies in Parkinson’s Disease Management offers a comprehensive exploration of the latest innovations and multidisciplinary approaches in Parkinson’s Disease treatment. The volume is organized into sections covering genetic therapies, gut microbiota, artificial intelligence, virtual reality, neuroprotective strategies, polypharmacy, and combination therapies. It addresses the integration of personalized medicine, neuroprotective diets, natural products, cognitive enhancers, and ethical considerations. Additional chapters introduce traditional medicine, music therapy, and the synergy between pharmacotherapy and complementary modalities. The book equips readers with the knowledge to implement innovative therapies, navigate complex ethical landscapes, and integrate multidisciplinary and complementary approaches.This reference is essential for those seeking to advance clinical practice and research in Parkinson’s Disease through the adoption of cutting-edge strategies.

  • Clinician’s Guide to Headache

    Head, Neck, and Face Pain Syndromes
    • 1 Edición
    • Pravin Thomas
    • Inglés
    Clinician’s Guide to Headache: Head, Neck, and Face Pain Syndromes is a clinically focused, case-based reference for neurologists, headache specialists, pain physicians, trainees, and allied clinicians caring for patients with head, neck, and facial pain. Rather than relying only on conventional disease-based descriptions, it reflects the realities of everyday practice: complex and overlapping syndromes, diagnostic uncertainty, secondary causes, comorbidities, and rapidly changing therapeutic options. Organized around real clinical scenarios, the book covers the full breadth of headache medicine, from classification, anatomy, history taking, examination, and pathophysiology to migraine, trigeminal autonomic cephalalgias, cranial neuralgias, CSF pressure disorders, neurovascular and inflammatory diseases, infections, metabolic causes, epilepsy-related headache, sleep-related disorders, ophthalmic presentations, pediatric headache, neck pain, and facial pain. Foundational sciences, such as anatomy, neuroradiology, pharmacology, and pathophysiology, are presented in a practical, case-oriented manner to support bedside decision-making. The text also addresses the important frontiers in modern headache care, biologics, percutaneous interventions, implantable and noninvasive neuromodulation, and integrative strategies, such as yoga, meditation, and nutrition.With contributions from an international faculty, this volume provides a pragmatic, modern, and multidisciplinary approach to one of the most challenging areas in clinical neuroscience

  • Immunotherapies for Neurological Disorders

    Unlocking the Brain's Defenses
    • 1 Edición
    • Akash Gautam + 1 más
    • Inglés
    Immunotherapies for Neurological Disorders: Unlocking the Brain's Defenses explores the complex intersection of both the immune and nervous systems and neurological disorders. This comprehensive guide details the vital role of immunology in understanding conditions from Alzheimer's and Parkinson's to autoimmune diseases like multiple sclerosis and Guillain-Barré syndrome. Each chapter reviews strategies, including the use of antibodies, recombinant proteins, and cutting-edge vaccine approaches to modulate immune responses in the brain. Readers will be presented with the therapeutic potential of immune cells, gene therapy, and RNA interference in combating these debilitating disorders, while also examining the role of nanotechnology in enhancing treatment efficacy.Aimed at neurologists, immunologists, researchers, and students alike, this book serves as an essential resource for the latest advancements in neurological disease treatment.

  • Progress in Motor Control

    Crossroads between Neurophysiology and Applications
    • 1 Edición
    • Mark L. Latash + 4 más
    • Inglés
    "Progress in Motor Control: Crossroads between Neurophysiology and Applications" offers an in-depth look at the evolving field of motor control, synthesizing the latest research. This volume explores the complex roles of the central nervous system in movement, featuring contributions from leading experts who use approaches ranging from basic physical principles to advanced control theory. It addresses applied aspects of motor control, focusing on recovery strategies for functional movements in patients with spinal cord injuries, subcortical disorders, and strokes. Organized into five sections, the book covers theoretical advances, neurophysiological mechanisms, motor learning, neural plasticity, and motor disorders, including topics like neural population dynamics and vestibulospinal reflexes. The final sections highlight strategies for improving recovery after neurological events. This resource bridges foundational research and clinical application, making it invaluable for researchers, clinicians, and students in motor control, neuroscience and rehabilitation.Divid... into five comprehensive parts, the book covers theoretical advances, neurophysiological mechanisms, motor learning, neural plasticity, and motor disorders, including essential topics like neural population dynamics and the dual role of vestibulospinal reflexes. Final sections highlight practical strategies for improving recovery outcomes following neurological events.

  • Pharmacological Foundations of Parkinson’s Disease

    From Mechanisms to Clinical Practice
    • 1 Edición
    • Wael Mohamed
    • Inglés
    Pharmacological Foundations of Parkinson's Disease: From Mechanisms to Clinical Practice provides a comprehensive guide on the pharmacological treatment of Parkinson's Disease, offering students and clinicians a combination of foundational knowledge and advanced clinical insights. The book bridges theoretical concepts with real-world clinical scenarios and equips readers with the tools necessary to effectively manage Parkinson's Disease in practice. Offering a detailed review of symptoms, treatment gaps, and emerging therapies, this book delves into the pathogenesis the disease, along with dopaminergic treatments and management of motor and non-motor symptoms.Providing updates on emerging therapies, including innovative treatment approaches, this book serves as a valuable reference for continuous learning and staying current with evolving practices and research in Parkinson's Disease management.

  • Applied Neuropsychology of Cerebrovascular Diseases

    A Practical Guide to Brain Arteries, Lesion Localization, and Rehabilitation Strategies
    • 1 Edición
    • Helmut Hildebrandt + 2 más
    • Inglés
    Applied Neuropsychology of Cerebrovascular Diseases: A Practical Guide to Brain Arteries, Lesion Localization, and Rehabilitation Strategies addresses the critical intersection of vascular neurology and neuropsychological rehabilitation. The book explores the pathophysiology of stroke, emphasizing the importance of cerebrovascular anatomy and lesion localization in understanding cognitive deficits. It provides essential knowledge for clinicians involved in stroke assessment and treatment, highlighting the need for integration of neuroimaging interpretation into neuropsychological practice. Early sections offer foundational insights into cerebrovascular anatomy, stroke mechanisms, and their typical cognitive and emotional impairments.The second section equips clinicians with practical skills to independently interpret brain scans, utilizing tools like MRIcron to accurately localize lesions. The final section focuses on targeted rehabilitation strategies for common stroke syndromes, including neglect, aphasia, visual field deficits, and disorders of consciousness, all of which are supported by real-world clinical guidance and emerging neuromodulation techniques such as tDCS.

  • Lights on for the Nervous System: Exploring the Effects of Photobiomodulation - Part A

    • 1 Edición
    • Volumen 189
    • Inglés
    Lights on for the Nervous System: Exploring the Effects of Photobiomodulation: Part A, Volume 189 in the International Review of Neurobiology series, highlights new advances in understanding how light interacts with the human body and brain. This comprehensive volume presents chapters written by an international board of authors, covering the history and theory of therapeutic light use, the underlying mechanisms of light–cell interactions, and the systemic effects of light exposure. It explores cognitive enhancement, sleep regulation, and microbiome modulation, as well as the potential of light-based interventions for neurodegenerative disorders, chronic pain, traumatic brain injury, depression, and retinal diseases.Specific sections cover History of Humans Using Light, Theory of Light: Why Should It Work, Mechanisms of Light, Systemic Effects of Light, Light Application and Dosage, How Does Light Affect Brain Activity, Light Talks: The Role of Biophoton in Cellular Communication, Biophotons: Communication with Light, Light Effects on Brain Activity: Simulations/Dynamic Function, Cognitive Enhancement through Transcranial Infrared Laser Stimulation: Insights from Research, Light Effects on the Microbiome, Lights On for Sleep, Exploring the Effect of Red and Near Infrared Light on Neurodegenerative Disease, Light Effects on Parkinson's Disease: Intracranial Application, Light Effects on Parkinson's Disease: Transcranial Application, and much more.

  • Bradley and Daroff's Neurology in Clinical Practice, 2-Volume Set

    • 9 Edición
    • Joseph Jankovic + 3 más
    • Inglés
    Covering all aspects of today’s neurology in an easy-to-read, clinically relevant manner, Bradley and Daroff's Neurology in Clinical Practice, 9th Edition, is a practical, dynamic resource for practicing neurologists, psychiatrists, neurosurgeons, physician extenders, neuroscientists, neuropsychologists, and trainees. This comprehensive two-volume set, authored by world renowned experts, is ideal for daily reference, featuring a unique organization by presenting symptom/sign and by specific disease entities―allowing you to access content in ways that mirror how you practice. A straightforward style, evidence-based information, and robust interactive content supplemented by treatment algorithms and images keep you up to date with all that’s current in this fast-changing field.

  • A Modern Atlas for Implantable Devices of the Spine, Brain, and Nerve

    For Pain, Movement Disorders, and Nerve Dysfunction
    • 1 Edición
    • Timothy R. Deer + 1 más
    • Inglés
    A Modern Atlas for Implantable Devices of the Spine, Brain and Nerve: For Pain, Movement disorders, and Nerve Dysfunction is a vital resource for medical practitioners and researchers in the rapidly evolving field of neuromodulation. This comprehensive reference navigates the intricate landscape of implantable technologies with a focus on new techniques, advanced waveforms and frequencies, and novel neural targets spanning the spine, brain, and peripheral nerves. This atlas introduces groundbreaking devices, including best practices tailored to enhance clinical outcomes. From spinal cord stimulation to intricate procedures involving the dorsal root ganglion, and sacral nerve, each section reviews both the anatomical nuances and procedural details, equipping practitioners with the expertise needed to tackle a diverse array of disease states and patient conditions.

  • Brain Energy Metabolism in Alzheimers Disease - Part C

    • 1 Edición
    • Volumen 188
    • Inglés
    Brain Energy Metabolism in Alzheimer’s Disease – Part C, Volume 188 in the International Review of Neurobiology series, presents the latest research on metabolic dysfunction and its role in neurodegenerative diseases. This volume brings together contributions from an international panel of experts, exploring the molecular, cellular, and systemic aspects of energy metabolism in Alzheimer’s disease and related disorders.Chapters in this release examine metabolic therapeutic targets in Alzheimer’s disease, alterations in brain energy metabolism in comparison with Parkinson’s disease, and the role of epigenetic modulation through natural compounds. Additional sections address mitochondrial dysfunction, disruption of metabolic pathways, and the contribution of glial cells to neurodegenerative processes.Further contributions explore metabolic disorders linked to Parkinson’s disease, signaling pathways in neurodegeneration, and advances in therapeutic and diagnostic strategies targeting key enzymes. The volume also highlights the role of intestinal microbiota, nanocarrier-based therapeutic approaches, and emerging treatments such as HDAC inhibitors. Together, these chapters provide a comprehensive overview of the mechanisms, biomarkers, and therapeutic prospects related to energy metabolism in neurodegenerative diseases, making this volume an essential reference for researchers and clinicians in neuroscience and neurobiology.

  • Brain Energy Metabolism in Alzheimers Disease - Part B

    • 1 Edición
    • Volumen 187
    • Inglés
    Brain Energy Metabolism in Alzheimer’s Disease – Part B, Volume 187 in the International Review of Neurobiology series, presents current advances and comprehensive reviews on metabolic dysfunction in neurodegenerative diseases. This volume brings together contributions from an international panel of experts, focusing on the molecular and cellular mechanisms underlying energy imbalance in Alzheimer’s disease and related disorders.Chapters in this release explore key processes such as autophagy and ESCRT pathways, tau modifications, insulin resistance, and mitochondrial dysfunction. Additional sections examine neurovascular–glial interactions, genetic and epigenetic factors in neurodegeneration, and the roles of metallospecies, noncoding RNAs, and phase separation in disease progression.Further contributions address neuroprotective signaling pathways, metabolic impairments in glucose and lipid homeostasis, and emerging diagnostic and therapeutic approaches, including liquid biopsy markers and targeted metabolic interventions. Together, these chapters provide an integrated overview of the mechanisms, biomarkers, and therapeutic opportunities associated with brain energy metabolism in neurodegenerative diseases, making this volume an essential reference for researchers and clinicians in neuroscience and neurobiology.

  • Imaging of Acute Encephalopathies, An Issue of Neuroimaging Clinics of North America

    • 1 Edición
    • Volumen 36-3
    • Natalia Nagornaya + 1 más
    • Inglés
    In this issue of Neuroimaging Clinics, guest editors Drs. Natalia Nagornaya and Gaurav Saigal bring their considerable expertise to the topic of Imaging of Acute Encephalopathies. Top experts discuss hypoxic ischemic encephalopathy; stroke-like syndromes in encephalopathy; metabolic derangement and vitamin deficiencies in encephalopathy; vascular and hematologic disorders; autoimmune, paraneoplastic, or idiopathic disorders in encephalopathy; and more.

  • Sports Neurology, An Issue of Neurologic Clinics

    • 1 Edición
    • Volumen 44-3
    • Amaal J. Starling
    • Inglés
    In this issue of Neurologic Clinics, guest editor Dr. Amaal J. Starling brings her considerable expertise to the topic of Sports Neurology. Top experts discuss brain health in the healthy athlete and management of sports-related neurologic injuries, including the assessment and management of sports-related concussion, spinal cord injuries, peripheral nerve injuries, and much more.

  • Brain Energy Metabolism in Alzheimers Disease - Part A

    • 1 Edición
    • Volumen 186
    • Inglés
    Brain Energy Metabolism in Alzheimer’s Disease – Part A, published as Volume 186 of the serial International Review of Neurobiology, provides a comprehensive and up‑to‑date synthesis of molecular, cellular, and systemic mechanisms underpinning energy dysregulation in neurodegeneration, with a primary focus on Alzheimer’s disease. This volume assembles expert-led reviews exploring key metabolic pathways—from glutamate–glutamine cycling and mitochondrial bioenergetics to neurovascular coupling, circadian regulation, and gut–brain axis interactions—while also examining emerging contributors such as environmental toxins, PFAS exposure, and microplastic-induced neurotoxicity. Together, these chapters illuminate how disrupted energy homeostasis intersects with oxidative stress, inflammation, and neuronal senescence, offering new insights into disease pathophysiology and therapeutic targeting.

  • Nanotherapeutics for Treating Neurodegenerative Disorders

    • 1 Edición
    • Manish K. Chourasia + 3 más
    • Inglés
    Nanotherapeutics for Treating Neurodegenerative Disorders is a comprehensive guide to the cutting edge field of nanotherapeutics. This book reviews the complex landscape of neurodegenerative disorders, outlining the nuances of treatment strategies and the imperative role of nanotechnology in revolutionizing therapeutic interventions. From explaining the transport mechanisms of the blood–brain barrier to unveiling the therapeutic potential of stem cell-derived nanocarriers, each chapter offers invaluable insights into the diverse array of nanotherapeutic approaches, helping to reshape the landscape of neurological healthcare. This book provides a comprehensive resource for clinicians, researchers, and students in the fields of neurology and nanotherapeutics.

  • Retina Assessments, Disease, and Treatments

    • 1 Edición
    • Volumen 218
    • Machelle T. Pardue
    • Inglés
    Retina Assessments, Disease, and Treatments, Volume Two explores retinal disease, assessment, and treatment for rehabilitation of visual function. Focusing on major retinal diseases and clinical assessments, including neuroimaging and electrophysiology, this volume highlights new restorative therapies such as gene therapy, stem cell therapy, retinal prosthetics, and novel tools to assess retinal function.

  • Behavioral Biometrics and Artificial Intelligence for Neurodegenerative Diseases Assessment

    • 1 Edición
    • Vincenzo Dentamaro + 2 más
    • Inglés
    Behavioral Biometrics and Artificial Intelligence for Neurodegenerative Diseases Assessment explores cutting-edge, non-invasive techniques for the early detection of neurodegenerative diseases. The book focuses on behavioral biometrics, which analyzes patterns in a person’s actions rather than directly measurable traits. By utilizing artificial intelligence methods—like machine learning and deep neural networks—it enables the observation of subtle changes in gait, handwriting, and speech. These advanced approaches offer promise for earlier and more accurate diagnosis, potentially improving outcomes for millions affected by conditions such as Alzheimer’s and Parkinson’s diseases through timely intervention and personalized care.In addition to its core coverage, the book delves into the practical applications of wearable sensors and the use of everyday devices like smartphones and tablets in assessments. It provides comprehensive chapters on how these technologies can aid clinicians and researchers in monitoring disease progression outside traditional clinical settings.

  • Cholinergic Drugs for Alzheimer's Disease

    From Central Cholinergic Neurotransmission to Drug Therapies and Natural Products with Multitarget Actions
    • 1 Edición
    • Cheorl-Ho Kim
    • Inglés
    Cholinergic Drugs for Alzheimer’s Disease: From Central Cholinergic Neurotransmission to Drug Therapies and Natural Products with Multitarget Actions addresses the urgent need for advanced resources in neuropharmacology. The first section presents mechanistic insights into cholinergic drugs, current hypotheses for Alzheimer’s Disease progression, neurotransmitter systems, receptor biology, and the evolution of acetylcholinesterase inhibitors, including hybrid and multi-target drugs. It also covers clinical status, neuromuscular blockers, non-adrenergic neurotransmitters, protein kinase inhibitors, inflammation modulation, NMDA antagonism, biomarkers, and AI-assisted drug discovery.The second section explores natural alkaloidal and non-alkaloidal compounds, molecular docking, SAR analysis, and daily consumable resources, with the third section investigating marine-derived AChE inhibitors, dual- and multi-target drug concepts, and emerging therapeutic compounds. This book equips the scientific community with a robust foundation for understanding and innovating in Alzheimer’s Disease therapy. By integrating molecular biology, pharmacology, and computational approaches, it empowers researchers and clinicians to address treatment challenges, optimize drug design, and leverage natural products for multifactorial intervention.

  • Retina Structure, Function, and Genetics

    • 1 Edición
    • Volumen 217
    • Machelle T. Pardue
    • Inglés
    Retina Structure, Function, and Genetics focuses on recent research on the ocular structure responsible for visual function. Introductory chapters cover epidemiology and genetics of the retina, while structural chapters cover development, anatomy, the fovea, retinal cell types, and vasculature. Additional content covers neurotransmitters and circuits, phototransduction, ganglion cell physiology, higher order visual processing, and color and spatial vision.

  • Minimally Invasive Spine Techniques

    Modern Approaches
    • 1 Edición
    • Timothy R. Deer + 1 más
    • Inglés
    An essential guide for mastering modern implantable devices in spine, brain, and nerve surgeries, offering comprehensive insights and cutting-edge techniques for optimal clinical outcomesMinimally Invasive Spine Techniques: Modern Approaches is an indispensable resource tailored for practitioners facing the daily challenges demanding precision, innovation, and comprehensive knowledge. This edited reference not only provides a detailed exploration of anatomy critical to procedural success but also equips practitioners with the latest techniques and tools in minimally invasive surgery. From patient selection criteria to surgical techniques and device applications, this atlas ensures that every facet of device implantation is approached with the highest standards of care and innovation. Richly illustrated with a pictorial atlas of best practices, it serves as an essential guide for training, ensuring optimal outcomes in clinical practice.

  • Imaging of Epilepsy, An Issue of Neuroimaging Clinics of North America

    • 1 Edición
    • Volumen 36-2
    • Robert E. Watson Jr. + 1 más
    • Inglés
    In this issue of Neuroimaging Clinics, guest editors Drs. Robert E. Watson, Jr. and Brian Burkett bring their considerable expertise to the topic of Imaging of Epilepsy. Top experts discuss cortical malformations; temporal lobe epilepsy and mesial temporal sclerosis; 7T MRI for epilepsy; nuclear imaging of epilepsy; MEG; fMRI for epilepsy; and more.

  • Neuro-Ophthalmology Update, An Issue of Neurologic Clinics

    • 1 Edición
    • Volumen 44-2
    • Andrew G. Lee + 3 más
    • Inglés
    In this issue of Neurologic Clinics, guest editors Drs. Andrew G. Lee, Peter Mortensen, Saif Aldeen Alryalat, and Osama Al Deyabat bring their considerable expertise to the topic of Neuro-Ophthalmology Update. Top experts discuss the various aspects of neuro-ophthalmology that enhance diagnostic capabilities, aid in the management of visual complications related to neurological disorders, and foster effective interdisciplinary collaboration with ophthalmologists.

  • The Brainstem

    • 1 Edición
    • Volumen 216
    • Inglés
    This volume on Brainstem consolidates research for a complete understanding of the anatomy and physiology of the Brainstem and how it affects assorted other systems in the body. The brainstem impacts breathing, the gastrointestinal system, the cardiac system, mood, pain, wakefulness, consciousness, and sleep. Pathologies can impact vision, motor control, hearing, balance, blood supply and is particularly involved in neurodegenerative diseases like Parkinson’s. The volume discusses how the brainstem operates in full health, pathologies associated with the brainstem and their impact, methods for monitoring brainstem function, and diagnosis and treatment of brainstem disorders. Monitoring and intervention is reliant on technologies to assess function. This volume will include CT, MRI, USG, angiography, BERA, and functional imaging.

  • Tic Disorders and Tourette Syndrome

    • 1 Edición
    • Volumen 215
    • Christos Ganos + 1 más
    • Inglés
    Tic Disorders and Tourette Syndrome is an essential resource that delves into the clinical aspects, treatments, and ongoing research related to tic disorders and Tourette syndrome. It covers a range of topics from primary to secondary and functional tics, providing differential diagnosis. The book is designed to offer foundational knowledge to neurologists, psychiatrists, neuropsychiatrists, and psychologists, while also catering to the needs of advanced readers. In addition to clinical presentations, the book discusses the epidemiology, etiology, and pathophysiology of tics, along with common neuropsychiatric comorbidities such as obsessive-compulsive disorder, ADHD, mood disorders, and intermittent explosive disorder. The volume also includes treatment options and clinical scales to evaluate tics, illustrated with video accompaniments and animal models.

  • Neuro-ophthalmological Pain

    Diagnosis and Treatment
    • 1 Edición
    • R. Silva-Néto + 1 más
    • Inglés
    Neuro-ophthalmologic... Pain: Diagnosis and Treatment is written to address the many problems faced by patients with ocular pain of neurological origin. These patients are often incorrectly referred to ophthalmologists and otolaryngologists to diagnose eye problems or sinus disease, respectively. While these ailments are neurological in nature, the average time between the onset of pain and a visit to a neurologist is 13 years. By this point, many patients have received at least one wrong diagnosis. Additionally, some patients have undergone several unnecessary investigative tests, received improper or flawed treatment, and continued to suffer. Neuro-ophthalmologic... Pain: Diagnosis and Treatment contains information on a multitude of often-overlooked ailments in a single, comprehensive volume, for use by the neurologist as well as for all practitioners looking to guide their patients toward appropriate care. It will provide potentially life-changing information for those with ocular pain with decreased vision, ocular pain with ophthalmoplegia or ophthalmoparesis, ocular pain with papilledema, ocular pain with autonomic manifestations, and ocular pain that has overlap with ocular disorders. Neuro-ophthalmologic... Pain: Diagnosis and Treatment is a powerful tool in helping physicians establish correct diagnoses, so that they may either provide proper treatment or refer their patients to the correct medical specialists.

  • Immunotherapies for Neurologic Diseases

    • 1 Edición
    • Volumen 214
    • Inglés
    Immunotherapies for Neurologic Diseases, Volume 214 explores how neuroimmunotherapies intervene by targeting key molecules and pathways responsible for tissue damage in the central and peripheral nervous systems. The book details approved treatments that modulate T-cell signaling, antigen presentation, B cells and their trophic factors, autoantibodies, Fc receptors, complement, cytokines, and cell adhesion molecules. Each chapter includes clear explanations and illustrations, helping clinicians understand the mechanisms of these drugs in autoimmune neurological diseases. The volume serves as a practical and comprehensive guide, making complex therapeutic approaches accessible to medical professionals and students.The second section highlights the latest therapies for major autoimmune neurological diseases, offering step-by-step algorithms and escalation strategies for selecting optimal treatments. Controversies and uncertainties in therapy choices are discussed by leading experts, while additional chapters address emerging immunotherapeutic approaches for neurodegenerative diseases and the evolving concept of treating autoimmune pain. The book also covers practical applications of traditional immunosuppressants, IVIg, and targeted monoclonal antibodies, with dedicated chapters on conditions such as encephalitis, NMOSD, multiple sclerosis, and stiff person syndrome.

  • Neuromonitoring Techniques

    Quick Guide for Clinicians and Residents
    • 2 Edición
    • Hemanshu Prabhakar
    • Inglés
    Neuromonitoring Techniques: Quick Guide for Clinicians and Residents, Second Edition continues to be the comprehensive resource designed to equip healthcare professionals with essential knowledge for effective patient care. This revised edition introduces new chapters that delve into cutting-edge areas of neuromonitoring, including Clinical Neuromonitoring, providing insights into real-world applications, Electroencephalogram... unraveling the intricacies of brain activity monitoring, and Brain Ultrasound, exploring the latest advancements in non-invasive imaging techniques. From the fundamentals in the Introduction to Neuromonitoring Techniques to advanced topics such as Cognitive Function Monitoring and Functional Neuroimaging, each chapter is precisely crafted to offer a quick yet thorough understanding of the respective techniques. Whether you are a seasoned clinician seeking to stay abreast of the latest advancements or a resident looking to build a strong foundation, this revised edition provides an accessible guide to the diverse realm of neuromonitoring.

  • Diabetes and Neurodegeneration

    • 1 Edición
    • Debasis Bagchi + 2 más
    • Inglés
    Diabetes and Neurodegeneration unlocks the complex interplay between diabetes and Neurodegeneration, reviewing the relationship between these two prevalent health challenges. This book begins with a simple guide to understanding high blood sugar, tracing the historical milestones of hyperglycemia, and unveiling the primary factors that contribute to diabetes development, from genetic predisposition to lifestyle hazards. The second section aims to bridge the gap between diabetes and dementia, presenting early clinical evidence, case studies, and susceptibility assessments that underscore the strong link between hyperglycemia and neurodegeneration. Biomarkers and pathways connecting these conditions are explored, including the role of Advanced Glycated End (AGE) products and their implications in protein misfolding and aggregation. The narrative extends to therapeutic strategies, evaluating the efficacy of antidiabetic drugs, targeting insulin resistance, and introducing novel interventions to arrest amyloid-associated pathogenesis. This comprehensive guide provides both clinicians and researchers with a thorough understanding of the intricate link between diabetes and neurodegeneration.

  • Updates on Pediatric Brain and Spine Tumors, An Issue of Neuroimaging Clinics of North America

    • 1 Edición
    • Volumen 36-1
    • Christopher Filippi + 1 más
    • Inglés
    In this issue of Neuroimaging Clinics, guest editors Drs. Christopher Filippi and Jane McEniery bring their considerable expertise to the topic of Updates on Pediatric Brain and Spine Tumors. Top experts discuss changes to the WHO classification for pediatric brain and spine tumors; circumscribed astrocytic tumors; glioneuronal tumors; congenital neonatal tumors; radiomics and AI for pediatric brain tumor; tumor predisposition syndromes; and more.

  • Atlas of Microsurgery of the Lateral Skull Base

    • 1 Edición
    • Mario Sanna + 5 más
    • Inglés
    Atlas of Microsurgery of the Lateral Skull Base is a practical resource for all clinicians interested in training for lateral skull base surgery. This new atlas of lateral skull base surgery allows readers to become familiar with the delicate lateral skull base, an important part of the body’s neurological system. Featuring step-by step dissection images, this resource is perfect for those studying anatomy of this region. Clinical surgical cases are also presented and discussed for each surgical approach, including relevant clinical and radiological background. Decision-making discussions provided for each clinical case ensure readers will fill any gaps in their neurosurgery training.

  • Pediatric Neurology

    Clinical and Imaging Case Studies
    • 1 Edición
    • Hugo A. Arroyo + 4 más
    • Inglés
    Pediatric Neurology: Clinical and Imaging Case Studies is a richly illustrated, case-based resource that explores the complementary roles of neurology and radiology for patient diagnosis and treatment. This unique volume is authored by world-class child neurologists and pediatric neuroradiologists who demonstrate the essential role of interdisciplinary collaboration in clinical care. Expert-selected cases comprise this valuable educational tool and reference text for diverse audiences including primary care physicians, neurologists, neurosurgeons, and neuroradiologists.

  • Placebo Responses in Neurologic Clinical Trials, An Issue of Neurologic Clinics

    • 1 Edición
    • Volumen 44-1
    • Aziz Shaibani + 1 más
    • Inglés
    In this issue of Neurologic Clinics, guest editors Drs. Aziz Shaibani and Fabrizio Benedetti bring their considerable expertise to the topic of Placebo Responses in Neurologic Clinical Trials. Top experts discuss the placebo response (not just the placebo effect) across a variety of neurologic clinical trials, providing an important overview of the occurrence and magnitude of the placebo response in different neurologic disorders. This issue offers key information for clinical trials in neurology as well as for clinical practice.

  • Hypnosis: Part B

    • 1 Edición
    • Volumen 185
    • Inglés
    Hypnosis: Part B, Volume 185, the latest release in the International Review of Neurobiology series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.

  • Fenichel. Neurología pediátrica clínica

    • 9 Edición
    • J. Eric Piña-Garza + 1 más
    • Español
    Con un enfoque práctico y accesible basado en la observación de los signos y los síntomas, la novena edición de Fenichel. Neurología pediátrica clínica proporciona una base sólida para el diagnóstico y el tratamiento de los principales trastornos neurológicos de la infancia, al tiempo que le permite estar al día de los avances en este campo. Se trata de una acreditada guía paso a paso que considera cada síntoma en términos de diagnóstico diferencial y tratamiento, reflejando la evaluación y el manejo de los pacientes en la práctica clínica. Esta edición revisada es una introducción ideal a este campo complejo y en continuo cambio.

  • Handbook of Parkinson's Disease Mechanisms

    • 1 Edición
    • Volumen 35
    • Rosario Moratalla + 1 más
    • Inglés
    The Handbook of Parkinson’s Disease Mechanisms offers an integrated overview of the fundamental research devoted to understanding its causes and mechanisms, highlighting recent advances and clinical significance. With a strong focus on cellular and animal model studies, this book also examines the etiology, pathophysiology, epidemiology and underlying symptoms of Parkinson’s disease.Written with an interdisciplinary approach, this book provides thorough research that will be of interest to researchers, clinicians and graduate students interested in neurodegenerative diseases.