Saltar al contenido principal
Elsevier

Libros en Psiconeurofarmacología

  • Neuropsychopharmacology

    • 1 Edición
    • Jahangir Moini + 2 más
    • Inglés
    Neuropsychopharmacol... reviews the principles of pharmacology with a focus on the central nervous system and autonomic nervous system. Beyond autonomic and central nervous system pharmacology, this volume uniquely discusses psychiatric disorders and the pharmacological interventions that are available for conditions including depression, schizophrenia and anxiety disorders. With a focus on these specific body systems, readers will see end-of-chapter questions that offer real-world case studies, as well as multiple-choice questions for further learning. Beneficial features and content also include two extensive examination tests, which each contain 100 questions for better learning or to be used in teaching, and a glossary. Helpful appendices cover high-alert medications and toxicology effects on the nervous system. Each chapter will contain classifications of medications, pharmacokinetics, mechanism of action, clinical indications and toxicities.

  • Prof. of Drug Substances, Excipients and Related Methodology

    • 1 Edición
    • Volumen 46
    • Abdulrahman Al-Majed
    • Inglés
    Profiles of Drug Substances, Excipients, and Related Methodology, Volume 46 contains comprehensive profiles of five drug compounds: Darunavir, Bisoprolol, Betaxolol, Rabeprazole and Irbesartan. In addition, the work contains a chapter reviewing Bioassay Methods and Their Applications in Herbal Drug Research. The comprehensive reviews in the book cover all aspects of drug development and the formulation of drugs, helping readers understand how the drug development community remains essential to all phases of pharmaceutical development. In addition, this work answers why such profiles are of immeasurable importance to workers in the field. The scope of the Profiles series encompasses review articles and database compilations that fall within one or more of the following five broad categories: Physical Profiles of Drug Substances and Excipients, Analytical Profiles of Drug Substances and Excipients, ADME Profiles of Drug Substances and Excipients, Methodology Related to the Characterization of Drug Substances and Excipients, and Methods of Chemical Synthesis.

  • Profiles of Drug Substances, Excipients, and Related Methodology

    • 1 Edición
    • Volumen 45
    • Harry G. Brittain
    • Inglés
    Profiles of Drug Substances, Excipients, and Related Methodology, Volume 45, presents comprehensive reviews of drug substances and additional materials, with critical review chapters that summarize information related to the characterization of drug substances and excipients. The series encompasses review articles, with this release focusing on Azilsartan Medoxomil, Piroxicam, Carbetapentane Citrate, Emtricitabine, Etrlotinib, Isotretinoin and Meloxicam.

  • Profiles of Drug Substances, Excipients, and Related Methodology

    • 1 Edición
    • Volumen 44
    • Harry G. Brittain
    • Inglés
    Profiles of Drug Substances, Excipients, and Related Methodology, Volume 44, presents comprehensive reviews of drug substances and additional materials, with critical review chapters that summarize information related to the characterization of drug substances and excipients. The series encompasses review articles, with this release focusing on Cefpodoxime proxetil, Levetiracetam, Paclitaxel, Sorafenib, Sucrose octaacetate, Thiouracil, Topiramate, Spectrophotometric analysis, and Cocrystal Systems of Pharmaceutical Interest: 2012-2014.

  • Life-Threatening Effects of Antipsychotic Drugs

    • 1 Edición
    • Peter Manu + 2 más
    • Inglés
    Life-Threatening Effects of Antipsychotic Drugs describes in detail more than 20 life-threatening effects associated with antipsychotics, presents the best available data on their incidence and case fatality, and gives comprehensive advice on diagnosis, management and preventive strategies. In addition, the book discusses the benefit of antipsychotic medication in a range of therapeutic indications, and demonstrates the gain in life-expectancy associated with clozapine use in severe mental illness despite its serious, potentially life-threatening adverse effects.

  • Emerging Targets and Therapeutics in the Treatment of Psychostimulant Abuse

    • 1 Edición
    • Volumen 69
    • Linda P. Dwoskin
    • Inglés
    This new volume of Advances in Pharmacology presents the emerging targets and therapeutics in the treatment of psychostimulant abuse. With a variety of chapters and the best authors in the field, the volume is an essential resource for pharmacologists, immunologists and biochemists alike.

  • The Nervous System

    Central Nervous System Drugs
    • 1 Edición
    • Walter S. Root + 1 más
    • Inglés
    Physiological Pharmacology: A Comprehensive Treatise, Volume II: The Nervous System — Part B, Central Nervous System Drugs focuses on the effects of drugs on the functions of the central nervous system. The selection first offers information on depressant and anticonvulsant drugs. Topics include neurophysiological substrate of drug action; pharmacological properties of selected muscle relaxants; anticonvulsants and their mechanisms; and definitive seizure mechanisms. The book also takes a look at antitussive drugs and psychic energizers and antidepressant drugs. The publication examines emetic and antiemetic drugs, as well as neural mechanisms of emesis, emetic syndromes and agents, and antiemetic agents. The text also reviews the effects of drugs on the eyes and synoptic transmission in the central nervous system. Discussions focus on the effect of drugs used in the therapy of ocular disease; undesirable eye effects of ophthalmic and other drugs; and chemical transmitters in the central nervous system. The selection is a dependable reference for readers interested in the effects of drugs on the central nervous system.

  • Advances in Drug Research

    • 1 Edición
    • Volumen 19
    • Bernard Testa
    • Inglés
    Each volume in this distinguished series presents authoritative reviews on topics of broad interest in drug research and on novel and established therapeutic classes. Acknowledged experts contribute in areas such as drug design, clinical and molecular pharmacology, drug metabolism, and mechanisms of action. Reviewers have consistently praised Advances in Drug Research for its comprehensive and lucid summaries of up-to-date knowledge.

  • Methods in Behavioral Pharmacology

    • 1 Edición
    • Volumen 10
    • F. van Haaren
    • Inglés
    Methods in Behavioral Pharmacology is unique in offering a complete description and critical evaluation of most, if not all, methods available to study the effects of drugs on behavior. It stands apart in that it is not limited to the analysis of a particular class of pharmacological agents in a limited number of paradigms. Methods in Behavioral Pharmacology covers all paradigms without reference to specific pharmacological compounds.The book provides a comprehensive overview of the methodology used to study the behavioral effects of legal and illegal drugs. It also provides an in-depth presentation of dependent variables, their quantification and a critical evaluation of their advantages and disadvantages. An excellent work, contributed to by well-known experts in the different fields of behavioral pharmacology.

  • Metal Toxicology

    Approaches and Methods
    • 1 Edición
    • Robert A. Goyer
    • Inglés
    Metal Toxicology addresses the effects of metals on human health, as well as their mechanisms of toxicity. Unlike most books on metal toxicity which are organized by individual metals, this book is arranged inan organ-by-organ basis. It deals with unifying mechanisms of metal toxicity within a given tissue, and with exposure of a tissue to more than one metal at a time.

  • Advances in Drug Research

    • 1 Edición
    • Volumen 17
    • Bernard Testa
    • Inglés
    This volume comprises five authoritative reviews on timely topics in drug research. The first two chapters deal with chemotherapeutic agents (selective antiviral agents and cepham antibiotics) and subsequent chapters deal with the cardiovascular system and topics in neuropharmacology.

  • Lithium and the Cell

    Pharmacology and Biochemistry
    • 1 Edición
    • Nicholas J. Birch
    • Inglés
    This up-to-date compilation addresses the scientific problems of determining a mode of action of lithium and provides a cross-disciplinary perspective. In addition to psychiatrists interested in the therapeutic uses of lithium, it will also be of interest to biochemists using lithium as an inhibitor of phosphoinositide signaling, immunologists studying lymphocytes, and dermatologists studying viral replication in the skin.

  • T-Lymphocyte and Inflammatory Cell Research in Asthma

    • 1 Edición
    • G. Jolles + 2 más
    • Inglés
    It is well established that asthma is an inflammatory disease of the airway mucosa and drugs like inhaled glucocorticoids are now commonly introduced early in therapy. A characteristic feature of this disease is the vast number of eosinophils in airway tissue, although many other migratory and resident inflammatory cells with the capacity to synthesize and release cytokines and putative asthma mediators are present in the inflamed mucosa. The cross-talk between lymphocytes and these cells and the role of cytokines in complex biological networks are currently areas of intense research.This volume gathers together chapters and discussions on the biology of immunocompetent and inflammatory cells, cellular interplay and communication, and on the relative importance of cells and mediators in disease.It should help contribute to further insights into the pathology of asthma and to the development of novel efficacious drugs for the treatment of asthma and related respiratory disorders.

  • Meyler's Side Effects of Psychiatric Drugs

    • 1 Edición
    • Jeffrey K. Aronson
    • Inglés
    Elsevier now offers a series of derivative works based on the acclaimed Meylers Side Effect of Drugs, 15th Edition. These individual volumes are grouped by specialty to benefit the practicing physician or health care clinician. The unwarranted effects of medications used in psychiatry can adversely affect a treatment plan. This book is critical in helping psychiatrists and mental health professionals assess the adverse effects of drugs such as antidepressants, mood stabilizers, hypnosedatives, and antipsychotic drugs.The material is drawn from the 15th edition of the internationally renowned encyclopedia, Meyler’s Side Effects of Drugs, and the latest volumes in the companion series, Side Effects of Drugs Annuals. Drug names have usually been designated by their recommended or proposed International Non-proprietary Names (rINN or pINN); when those are not available, clinical names have been used. In some cases, brand names have been used.This volume is critical for any health professional involved in the administration of psychiatric mediations.

  • Animal and Translational Models for CNS Drug Discovery: Psychiatric Disorders

    • 1 Edición
    • Robert A. McArthur + 1 más
    • Inglés
    Psychiatric Disorders is written for researchers in both academia and the pharmaceutical industry who use animal models in research and development of drugs for psychiatric disorders such as anxiety, obsessive-compulsive disorder, depression, schizophrenia, bipolar disorder, ADHD, and autistic spectrum disorder. Psychiatric Disorders has introductory chapters expressing the view of the role and relevance of animal models for drug discovery and development for the treatment of psychiatric disorders from the perspective of (a) academic basic neuroscientific research, (b) applied pharmaceutical drug discovery and development, and (c) issues of clinical trial design and regulatory agencies limitations. Each volume examines the rationale, use, robustness and limitations of animal models in each therapeutic area covered and discuss the use of animal models for target identification and validation. The clinical relevance of animal models is discussed in terms of major limitations in cross-species comparisons, clinical trial design of drug candidates, and how clinical trial endpoints could be improved. The aim of this series of volumes on Animal and Translational Models for CNS Drug Discovery is to identify and provide common endpoints between species that can serve to inform both the clinic and the bench with the information needed to accelerate clinically-effective CNS drug discovery. This is the first volume in the three volume-set, Animal and Translational Models for CNS Drug Discovery 978-0-12-373861-5, and is also available for purchase individually.

  • Encyclopedia of Violence, Peace, and Conflict

    • 1 Edición
    • Lester R. Kurtz
    • Inglés
    The Encyclopedia of Violence, Peace, and Conflict, a three-volume set written by more than 200 eminent contributors from around the world, takes advantage of increasing, worldwide awareness in the public, private, commercial, and academic sectors about manifestations of violence in all segments of society. While the contributors do not use these volumes to make specific arguments, they do describe and clarify the developments in thought that have led to current theories about and positions on violence and peace. Our reviewers consistently note that while many in-depth studies of war, peace, and aggression exist, the attendant specialization keeps scholars from learning about related fields. No publication competing with the Encyclopedia of Violence, Peace, and Conflict can satisfy their need for a vast introductory work to such a diverse and socially-important field. This major work includes more than 190 multidisciplinary articles with over 1,000 cross-references and more than 2,000 bibliography entries for further reading which are arranged alphabetically for easy access.

  • Cytokines

    • 1 Edición
    • Anthony R. Mire-Sluis + 1 más
    • Inglés
    This book provides comprehensive coverage of the cytokines from a pharmacological approach. The chapters are presented in a consistent format allowing easy cross-reference, with sample diagrams and a summary table of essential facts for each chapter at the end of the book.Cytokines is unique in stressing cytokine biology and the application of research data to provide disease therapy. With 33 detailed and up-to-date chapters about individual cytokines, this comprehensive reference will provide both clinicians and researchers in immunology and pharmacology with invaluable information.

  • International Review of Neurobiology

    • 1 Edición
    • Volumen 39
    • Inglés
    Since 1959, International Review of Neurobiology has been a well known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. This important serial is now being combined with Neuroscience Perspectives and Methods in Neurosciences. This combination results in a series that reaches a wider audience and publishes a greater number of thematic volumes.

  • Neural Networks in QSAR and Drug Design

    • 1 Edición
    • James Devillers
    • Inglés
    Comprehensive and impeccably edited, Neural Networks in QSAR and Drug Design is the first book to present an all-inclusive coverage of the topic. The book provides a practice-oriented introduction to the different neural network paradigms, allowing the reader to easily understand and reproduce the results demonstrated. Numerous examples are detailed, demonstrating a variety of applications to QSAR and drug design.The contributors include some of the most distinguished names in the field, and the book provides an exhaustive bibliography, guiding readers to all the literature related to a particular type of application or neural network paradigm. The extensive index acts as a guide to the book, and makes retrieving information from chapters an easy task. A further research aid is a list of software with indications of availablility and price, as well as the editors scale rating the ease of use and interest/price ratio of each software package. The presentation of new, powerful tools for modeling molecular properties and the inclusion of many important neural network paradigms, coupled with extensive reference aids, makes Neural Networks in QSAR and Drug Design an essential reference source for those on the frontiers of this field.

  • Guidebook on Molecular Modeling in Drug Design

    • 1 Edición
    • N. Claude Cohen
    • Inglés
    Specially designed computer software is revolutionizing procedures for structured or rational drug design and discovery. The Guidebook on Molecular Modeling in Drug Design serves as a manual for the analysis ofmolecular structure and the correlation of these structures with pharmacological reactions. Intended as an introductory guide for advanced students and professionals with an interest in computer-assisted modeling for drug design and discovery, this bookwill also be of interest to medicinal and organic chemists, pharmaceutical researchers, pharmacologists, and biochemists who want to gain further insight into this rapidly advancing field.Molecular modeling is assuming an important role in the understanding of three-dimensional aspects in the specificity of drug-receptor interactions at the molecular level. This research area has become a well-established discipline in pharmaceutical research. It has created unprecedented opportunities in assisting medicinal chemists in the design of new therapeutic agents. Advances made in computer hardware and in theoretical medicinal chemistry have brought high-performance computing and graphics tools within reach of most academic and industrial laboratories, facilitating the development of useful approaches to rational drug design.The Guidebook on Molecular Modeling in Drug Design serves as a manual for the analysis of the molecular structure of biological molecules and drugs and the correlation of these structures with pharmacological actions. Intended as a guide for advanced students and professionals with an interest in computer-assisted modeling for drug design and discovery, this book will also be of interest to medicinal and organic chemists, pharmaceutical researchers, pharmacologists, and biochemists who want to gain further insight into this rapidly advancing field.

  • Doing What Works in Brief Therapy

    A Strategic Solution Focused Approach
    • 1 Edición
    • Ellen K. Quick
    • Inglés
    The first of its kind, Doing What Works in Brief Therapy is a guidebook to strategic solution focused therapy, a model which combines the principles and techniques of the Mental Research Institute's brief strategic therapy and the Brief Family Therapy Center's solution focused therapy. The book explains how the strategic emphasis on clarification of the problem and interruption of what does not work can complement and enhance the solution-focused emphasis on amplification of what does work. The text reviews the theory and presents specific treatment techniques. Case examples illustrate how the model has been used in brief, intermittent, and single-session therapy in a managed care setting. Brief psychotherapy doesn't have to result in chronic frustration for the therapist or superficial, second-rate care for the client. This book presents an approach that is upbeat, practical, and eminently workable in managed care. The reader learns to focus on critical issues with exquisite precision and to construct creative, individualized interventions that amplify what works and interrupt what does not.

  • Handbook of Perception and Action

    Perception
    • 1 Edición
    • Wolfgang Prinz + 1 más
    • Inglés
    This volume combines the classical fields of perception research with the major theoretical attitudes of today's research, distinguishing between experience- versus performance-related approaches, transformational versus interactional approaches, and approaches that rely on the processing versus discovery of information. Perception is separated into two parts. The first part deals with basic processes and mechanisms, and discusses early vision and later, yet still basic, vision. The second covers complex achievements with accounts of perceptual constancies and the perception of patterns, objects, events, and actions.

  • Advances in Heterocyclic Chemistry

    • 1 Edición
    • Volumen 64
    • Inglés
    Established in 1960, Advances in Heterocyclic Chemistry is the definitive serial in the area--one of great importance to organic chemists, polymer chemists, and many biological scientists. Every fifth volume ofAdvances in Heterocyclic Chemistry contains a cumulative subject index.

  • Annual Reports in Medicinal Chemistry

    • 1 Edición
    • Volumen 30
    • James A. Bristol
    • Inglés
    Praise for the Series:"This series is one of the very few annual publications which justify the title of an absolute must for the pharmacologist, chemist, or physician who is interested in the chemistry of drug development."--Enzym... book is strongly recommended for researchers, teachers, students, administrators - in short, anyone whose interests impinge on medicinal chemistry. In view of the work's documented reference value, it is a must for inlusion in the scientist's personal library."--Journal of Medicinal Chemistry"All topics are covered in sufficient depth, with extensive references, to allow either the specialist or the novice to be informed of the latest developments in a particular area of medicinal chemistry."--Norman Gilman, Hoffmann-La Roche, Inc, in the JOURNAL OF PHARMACEUTICAL SCIENCESAdvances in Medicinal Chemistry continues to provide timely and critical reviews of important topics in medicinal chemistry together with an emphasis on emerging topics in the biological sciences, which are expected to provide the basis for entirely new future therapies.

  • Advances in Heterocyclic Chemistry

    • 1 Edición
    • Volumen 63
    • Inglés
    Established in 1960, Advances in Heterocyclic Chemistry is the definitive serial in the area-one of great importance to organic chemists, polymer chemists, and many biological scientists. Every fifth volume ofAdvances in Heterocyclic Chemistry contains a cumulative subject index.

  • Chemistry and Pharmacology

    • 1 Edición
    • Volumen 46
    • Inglés
    Internationally acclaimed for more than forty years, this serial, founded by the late Professor R.H.F. Manske, continues to provide outstanding coverage of the rapidly expanding field of the chemotaxonomy, structureelucidation... synthesis, biosynthesis, and biology of all classes of alkaloids from higher and lower plants, marine organisms, or various terrestrial animals. Each volume provides, through its distinguished authors, up-to-date and detailed coverage of particular classes or sources of alkaloids. Over the years, this series has become the standard in natural product chemistry to which all other book series aspire. The Alkaloids: Chemistry and Pharmacology endures as an essential reference for all natural product chemists and biologists who have an interest in alkaloids, their diversity, and their unique biological profile.

  • Advances in Heterocyclic Chemistry

    • 1 Edición
    • Volumen 62
    • Inglés
    Established in 1960, Advances in Heterocyclic Chemistry is the definitive serial in the area--one of great importance to organic chemists, polymer chemists, and many biological scientists. Every fifth volume ofAdvances in Heterocyclic Chemistry contains a cumulative subject index.

  • Immunopharmacology of Free Radical Species

    • 1 Edición
    • Inglés
    Free radicals have been implicated in a entire host of different human disease states, which suggests that although they may not have a pivotal causal role, they are involved in the perpetuation of disease. In recentyears, it has become evident that although free radicals most certainly do have this role in perpetuating inflammatory reactions, they have perhaps a far more important role in acting as second messenger systems to maintain normal cell function. It is theperturbations of these reactions which pose the most intriguing therapeutic challenges. This volume deals with various basic mechanisms of free radical processes and injury. The emphasis in each case is on potential therapeutic strategies developing fromthis new knowledge.

  • Mechanisms and Models in Rheumatoid Arthritis

    • 1 Edición
    • B. Henderson + 2 más
    • Inglés
    Rheumatoid arthritis is a bewilderingly complex disease involving the interactions of many, and varied, cell populations and multiple families of low and high molecular mass mediators. We are only slowly beginning to understand the mechanisms that produce the local and systematic pathology clinically recognized as rheumatoid arthritis. Increasingly, use is being made of experimental models of this disease in an effort to test hypotheses about putative pathological mechanisms and to investigate the effect of novel therapeutic agents. A major section of this book covers these experimental models in great detail from their development through to reviews of the most recent information on each model.Mechanisms and Models in Rheumatoid Arthritis brings together a group of eminent researchers from the fields of clinical rheumatology, pathology, experimental pathology, immunology, connective tissue biochemistry, microbiology, pharmacology and developmental biology to describe the current views of the cellular and humoral mechanisms that drive the pathology of rheumatoid arthritis and experimental models of rheumatoid arthritis.

  • International Review of Neurobiology

    • 1 Edición
    • Volumen 36
    • Inglés
    Published since 1959, this serial presents in-depth reviews on key topics in neuroscience, from molecules to behavior. The serial stays keenly attuned to recent developments in the field through the contributions offirst-class experts. Neuroscientists as well as clinicians, psychologists, physiologists, and pharmacologists will find this serial an indispensable addition to their library.

  • Sigma Receptors

    • 1 Edición
    • Volumen 12
    • Inglés
    This is the 12th in the Neuroscience Perspectives Series. The existence of sigma receptors in the central nervous system has only relatively recently been established. In line with the aims of Neuroscience Perspectives, this volume will cover the historical background of the subject, together with the physiological, molecular biological and pharmacological aspects, with a discussion on the concept of sigma receptors subtypes and their postulated relevance for CNS disorders.

  • International Review of Neurobiology

    • 1 Edición
    • Volumen 33
    • Inglés
    Published since 1959, this serial presents in-depth reviews of key topics in neuroscience, from molecules to behavior. The serial stays keenly atuned to recent developments through the contributions of first-class experts in the many fields of neuroscience. Neuroscientists as well as clinicians, psychologists, physiologists and pharmacoloists will find this serial an indispensable addition to their library.