Saltar al contenido principal
Elsevier

Libros en Ciencias de la Vida

  • Systemic Lupus Erythematosus

    Basic, Applied and Clinical Aspects
    • 3 Edición
    • George C. Tsokos
    • Inglés
    Systemic Lupus Erythematosus: Basic, Applied and Clinical Aspects has been an essential resource for scientists and clinicians in this field since its original publication in 2015. The third edition of this work has been completely updated and expanded with the latest scientific and clinical developments in Systemic Lupus Erythematosus (SLE) to date. Contributors at the forefront of each topic come together to enhance content on epidemiology and diagnosis, pathogenesis, mechanisms of tissue damage, clinical aspects of the disease, antiphospholipid syndrome, and treatments. Also added is the latest information on new treatments, criteria, monogenic forms of lupus, insights on the role of microbiome, and advances in understanding disease pathogenesis. This must-have reference is an indispensable resource for specialists in the diagnosis and management of patients with SLE as well as early career or experienced investigators studying basic aspects of the disease. It is a tool for measurement of clinical activity for pharmaceutical development and basic research of the disease, and a key reference work for hospital libraries.

  • Encyclopedia of Animal Behavior

    • 3 Edición
    • Benjamin Oldroyd
    • Inglés
    Encyclopedia of Animal Behavior, Third Edition, Four Volume Set is a unique curated collection of punchy essays on all aspects of animal behavior, written by experts and carefully edited for readability and accessibility. Animal behavior is usually defined as what animals do, i.e. their movements. We can ask how they move, (i.e. the physiological and neurological causes of movement) and why they move. To answer this latter question, behavioralists generally turn to evolutionary explanations. The Encyclopedia gives equal weight to these ‘how’ (proximate) and `why` (ultimate) explanations of animal behavior. The third edition updates and expands the previous version to cover all substantive topics in the field. Animal behavior is one of the largest subdisciplines in biology. Therefore, chapters focus on broad concepts and avoid becoming entrapped in taxon-specific detail. To illustrate this, one could consider the topic ‘cooperative hunting’. One way to cover this topic would be to have individual chapters on hunting in lions, mongoose, African wild dogs, army ants, dolphins etc. But it would serve the reader much better if a comparative approach was taken to see if there are commonalities across taxa. For example, is communication necessary for cooperative hunting? Is there any evidence of planning or is every hunt opportunistic? This comparative approach requires authors to provide a synthesis, pushing beyond specific taxa of expertise, but helps readers making useful connections. This is a fundamental feature of this work. This edition retains chapters on the historical development of the field, which is important to our understanding of where the discipline sits today, but similarly the work is forward leaning, including the authors` perspective of where their discipline is headed. Structured chapters and cross-references help readers following their interests with ease. Like a bird field guide, this encyclopedia is an entrée to deeper knowledge. Readers of the encyclopedia are encouraged to explore beyond individual chapters via links to related ones, key reviews and relevant online material.

  • Brain Shuttle Peptides: Development and Applications

    • 1 Edición
    • Volumen 105
    • Inglés
    Advances in Pharmacology, Volume 105, a new volume in this ongoing series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics, including Introduction to brain shuttle peptides, In silico optimization of brain shuttle properties for passive diffusion, Shuttles derived from natural proteins, Shuttles derived from phage display, Chemically enhanced brain shuttle peptides, Brain delivery of gold nanoparticles, Brain delivery of lipid nanoparticles, Brain delivery of therapeutic proteins, In vitro BBB models for the study of brain shuttle transport, Physiological strategies for delivery across the BBB, and Polymeric Nanoparticles.

  • Nanotherapeutics for Treating Neurodegenerative Disorders

    • 1 Edición
    • Manish K. Chourasia + 3 más
    • Inglés
    Nanotherapeutics for Treating Neurodegenerative Disorders is a comprehensive guide to the cutting edge field of nanotherapeutics. This book reviews the complex landscape of neurodegenerative disorders, outlining the nuances of treatment strategies and the imperative role of nanotechnology in revolutionizing therapeutic interventions. From explaining the transport mechanisms of the blood–brain barrier to unveiling the therapeutic potential of stem cell-derived nanocarriers, each chapter offers invaluable insights into the diverse array of nanotherapeutic approaches, helping to reshape the landscape of neurological healthcare. This book provides a comprehensive resource for clinicians, researchers, and students in the fields of neurology and nanotherapeutics.

  • Starch Conjugates

    Properties and Applications
    • 1 Edición
    • Aayushi Deepak Kadam + 1 más
    • Inglés
    Starch Conjugates: Properties and Applications a volume in the Applications of Starches in Food and Packaging Series, compiles the latest research findings, methodologies, and case studies of starch conjugates synthesis techniques and applications across different industries, such as Food, Agriculture, Pharmaceutical, and Biomedical Engineering. The book brings detailed analysis and practical insights into the synthesis, characterization, and utilization of starch conjugates, ultimately fostering innovation and an eco-friendly alternative to conventional materials, driving advancements in materials science and technology. Practical case studies and real-world examples offer practical guidance to researchers and industry professionals, aiding them in developing and implementing starch conjugate-based solutions. The book also serves as a problem-solving resource for those facing challenges in utilizing starch conjugates, offering strategies, best practices, and expert advice to overcome obstacles and optimize outcomes. With contributions from experts across various disciplines, the book provides an interdisciplinary perspective, fostering collaboration and knowledge exchange among researchers and professionals from different backgrounds.

  • Indian Spices for Type 2 Diabetes

    Molecular Mechanisms and Pharmacological Insights
    • 1 Edición
    • Ashutosh Gupta + 2 más
    • Inglés
    Indian Spices for Type 2 Diabetes: Molecular Mechanisms and Pharmacological Insights explores the relationship between traditional Indian spices and their potential role in the management of Type II diabetes. The book discusses the bioactive compounds found in well-known spices such as turmeric, ginseng, cloves, cardamom, fenugreek, black pepper, and tulsi, among others. Each chapter provides in-depth analysis of molecular and pharmacological mechanisms, highlighting how these spices can potentially benefit glucose metabolism and insulin sensitivity. By integrating scientific findings, this book serves as an invaluable resource for researchers and clinicians seeking to understand how these natural ingredients can be harnessed in diabetes care.In addition to examining the therapeutic potential of these spices, the book addresses critical considerations such as the impact of dietary spices on the gut microbiome, potential toxicity, and drug interactions that may arise in clinical practice. Regulatory and safety aspects of incorporating herbal remedies into diabetes management are thoroughly discussed, making this a vital reference for nutritionists, clinicians, dietitians, and pharmaceutical professionals.

  • Toxicological Survey of African Medicinal Plants

    • 2 Edición
    • Victor Kuete
    • Inglés
    Toxicological Survey of African Medicinal Plants, Second Edition bridges traditional knowledge with modern science, providing a comprehensive and detailed overview of toxicological studies related to traditionally used African medicinal plants with special emphasis on practical insights and scientifically validated methodologies, and tools used for data collection and interpretation. Completely revised and updated, the book considers the physical parameters of novel plants and their effect on specific areas of the body and overall human health, including chapters dedicated to genotoxicity, hepatotoxicity, nephrotoxicity, cardiotoxicity, neurotoxicity, and specific organs and systems.The new edition also considers advances in omics approaches and the increased use of advanced analytical techniques to understand plant toxicity and improved the identification of toxic compounds in medicinal plants. With contributions from a distinguished team of researchers in the field, this book is an invaluable resource for researchers, advanced students and postgraduates, industry professionals, and policymakers who require an integrated understanding of toxicology, pharmacology, ethnopharmacology, as well as regulatory and policy frameworks for African medicinal plants.

  • The Exposome in Cancer Disparities

    Influence of Environmental and Infectious Factors in LMICs
    • 1 Edición
    • Zodwa Dlamini
    • Inglés
    The Exposome in Cancer Disparities: Influence of Environmental and Infectious Factors in LMICs examines how environmental and infectious factors drive cancer inequities in low- and middle-income countries (LMICs). The book introduces the exposome as a comprehensive framework to understand complex risk factors, such as environmental toxins, climate change, and infectious agents like HPV and HIV. The book combines scientific insights, real-world case studies, and practical strategies from international experts, highlighting region-specific contributors to cancer disparities. Structured into thematic sections, it offers a holistic view of the challenges faced by LMICs and provides actionable, evidence-based solutions tailored to resource-limited settings.The work emphasizes the importance of multidisciplinary approaches and international collaboration to develop effective prevention and policy strategies. It will benefit researchers, policymakers, and healthcare professionals by deepening understanding of cancer risk factors, fostering global cooperation and guiding targeted interventions to reduce health inequities and improve outcomes worldwide.

  • Viruses as Therapeutic Agents for Cancer

    • 1 Edición
    • Volumen 171
    • Inglés
    Viruses as Therapeutic Agents for Cancer, Volume 171 in the Advances in Cancer Research series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Coxsackievirus virotherapy, Oncolytic reovirus, Cancer immunotherapy with oncolytic myxoma virus, Zika Virus as an Oncolytic Therapy, Nonreplicative adenoviral vectors for cancer, VSV Oncolytic Virotherapy, AAV vectors for cancer gene therapy, Adenovirus cancer vaccines, Advancing Clinical Translation of Oncolytic Adenoviruses, and Immunotherapuetic Cancer Terminator Viruses.

  • Nanobiotechnology for Clinical Adoptability and Application

    • 1 Edición
    • Pawan Kumar Maurya + 3 más
    • Inglés
    Nanobiotechnology for Clinical Adoptability and Application offers an overview of bioanalytical methods and medical biotechnological applications in diagnostic and therapeutics. The book discusses modern concepts and bioanalytical methodologies in nanoscience and nanobiotechnology and their integration in real-time point-of-care applications which has emerged as a significant area of industrial research. It explores medical diagnostic use of different imaging and biosensing technologies, including biochemical methods, electrochemical sensors to detect infectious diseases, and microfluidics-based bioanalytical systems. It also covers biotechnological approaches to experimental therapeutics and theranostics.Ethical and regulatory considerations in biomedicine and medical diagnostics round out the coverage making this book a valuable resource for researchers, faculty, post-graduate students and professionals in biotechnology, biochemistry, nanotechnology, biomedical engineering, medicine, pharmaceutical sciences, or any related biomedical discipline.

  • Nutritional Epigenomics

    • 2 Edición
    • Volumen 14
    • Bradley S. Ferguson
    • Inglés
    Nutritional Epigenomics, Second Edition, Volume Fourteen in the Translational Epigenetics series, offers a comprehensive overview of nutritional epigenomics as a mode of study, along with nutrition’s role in the epigenomic regulation of disease, health, and developmental processes. Here, an expert team of international contributors introduces readers to nutritional epigenomic regulators of gene expression, our diet’s role in epigenomic regulation of disease and disease inheritance, caloric restriction and exercise as they relate to recent epigenomic findings, and the influence of nutritional epigenomics over circadian rhythms, aging and longevity, and fetal health and development, among other processes.Disease specific chapters address metabolic disease (obesity and diabetes), cancer, and neurodegeneration, among other disorders. Diet-gut microbiome interactions in the epigenomic regulation of disease are also discussed, as is the role of micronutrients and milk miRNAs in epigenetic regulation. Finally, chapter authors examine ongoing discussions of race and ethnicity in the social-epigenomic regulation of health and disease. This new edition has been fully updated to reflect current research in the field.

  • Advances in Tablet Manufacturing Technologies

    • 1 Edición
    • Honey Goel + 2 más
    • Inglés
    Advances in Tablet Manufacturing Technologies consolidates cutting-edge information on the latest technologies in tablet design and manufacturing, addressing the pressing need for innovation in an increasingly complex global market. The book is structured to provide a thorough understanding of tablet technology, beginning with foundational concepts and progressing through specialized topics. Key sections explore the historical context of tablet development, the significance of pharmaceutical excipients, preformulation aspects, and the physics of tablet compression. Subsequent chapters explore advanced topics, including coated tablets, modified-release formulations, organ-specific tablets, and state-of-the-art innovations like 3D printed tablets.Each chapter is enriched with practical examples and case studies, ensuring that readers can apply theoretical knowledge to real-world scenarios. With contributions from a diverse group of national and international experts, this book is an invaluable asset for scientists in academia and industry alike. It elucidates preformulation parameters, outlines regulatory frameworks, and discusses recent advances in excipient technology and in-process testing equipment.

  • Retina Assessments, Disease, and Treatments

    • 1 Edición
    • Volumen 218
    • Machelle T. Pardue
    • Inglés
    Retina Assessments, Disease, and Treatments, Volume Two explores retinal disease, assessment, and treatment for rehabilitation of visual function. Focusing on major retinal diseases and clinical assessments, including neuroimaging and electrophysiology, this volume highlights new restorative therapies such as gene therapy, stem cell therapy, retinal prosthetics, and novel tools to assess retinal function.

  • Advances in Applied Microbiology

    • 1 Edición
    • Volumen 133
    • Inglés
    Advances in Applied Microbiology, Volume 133 presents a comprehensive exploration of the latest innovations in applied microbiology. The book delves into the diverse applications of microbiology across various industries, including agriculture, food production, biotechnology, environmental science, and healthcare. Through a collection of insightful chapters authored by experts in the field, readers are offered in-depth analyses of cutting-edge research, emerging trends, and practical applications of microbiological principles.From novel microbial technologies to the impact of microbiomes on human health and beyond, this book serves as a valuable resource for researchers, professionals, and students seeking to stay informed and inspired by the exciting advancements.

  • Transposable Elements in Health and Disease

    • 1 Edición
    • Volumen 116
    • Inglés
    Transposable Elements in Health and Disease, Volume 116 in the Advances in Genetics series, highlights new advances in the field, with this new volume presenting comprehensive chapters on a variety of timely topics. Specific chapters examine Transposable Elements in Human Cancer: Regulation, Activation, and Genomic Consequences, Retrotransposons as both “architects” and “saboteurs” in the nervous system, Shaping Mammalian Genomes: The Regulation and Co-option of Transposable Elements, Transposable element analysis in -omics data, and Transposable elements in Aging: from biomarkers to effectors.Together, these contributions provide valuable insights into the mechanisms and impacts of transposable element activity, advancing our understanding of their broad significance in genetics, development, health, and disease.

  • Neuroscience for Sleep Medicine Part A

    • 1 Edición
    • Volumen 302
    • Inglés
    Neuroscience for Sleep Medicine series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Bioorthogonal Labeling

    • 1 Edición
    • Volumen 731
    • Inglés
    Biorthogonal Tagging, Volume 731 in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters such as Staudinger Ligations and Related Reactions: Scope and Applications in Chemical Biology, Strain-Promoted Bioorthogonal Cycloadditions to Investigate Sialyltransferases Promiscuity Towards Unnatural Sialic Acids, Practical Guidelines for the Bioorthogonal AMI–Isonitrile Ligation, Nitrones and Other Dipoles in Bioorthogonal Chemistry Applications, 1,2-Aminothiol-Speci... Conjugation for Dual-Color Fluorescent Labeling via Ultrafast TAMMs, Genetic Incorporation of Bicyclononyne for Cell-Surface Protein Labeling via Tetrazine Ligation, and much more.Additional chapters cover Genetic Code Expansion for Single Noncanonical Amino Acid Incorporation into SARS-CoV-2 Omicron Spike on Amber-Free Lentiviral Particles, Bioorthogonal Click-Chemistry Labeling and Visualization of Dual Noncanonical Amino Acid–Incorporated HIV-1 Env on Intact Virions, Studying Bacterial Glycans with Azidosugars and Bioorthogonal Chemistry, Bioorthogonal Tagging of DNA and RNA, Efficient Labeling of Pathogenic Fungal Chitin with Bioorthogonal Probes, and many more timely topics.

  • Current Approaches to Cryo-electron Microscopy

    • 1 Edición
    • Volumen 223
    • Inglés
    Current Approaches to Cryo-electron Microscopy, Volume 223 provides a comprehensive overview of the field, tracing its evolution from early structural studies to modern pipelines powered by deep-learning algorithms for helical reconstruction. The book addresses the persistent bottleneck of sample preparation, detailing the physical challenges of fibril clumping and interfacial adsorption, alongside emerging solutions to these problems. Chapters in this new release include Advancing biological understanding of the poxvirus scaffold through breakthroughs in cryo-electron microscopy, Pursuing the physics of cryoEM image formation, AI Tools for Cryo-EM: Protein Particle Picking, Density Map Enhancement, and Atomic Model Building, and much more.Additional chapters cover Cryo-EM of Amyloid Fibrils: Advances, Challenges, and Translational Applications, Computational Approaches for Protein Complex Modeling for Intermediate Resolution Cryo-EM Maps, Calcium-sensing receptor, involved in the oral perception of the kokumi substances, Insights into the Structure and Diversity of the Bacterial Flagellum from cryo-EM studies, Overview and future potential in structural studies of bacteriophages by cryo-electron microscopy, and more.

  • Advances in Insect Physiology

    • 1 Edición
    • Volumen 71
    • Inglés
    Advances in Insect Physiology, Volume 71 in this ongoing series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Virus Infection and its Endocrinological Regulation in Infected Insects, Insect Orphan Genes: Drivers of Evolutionary Innovation and Emerging Tools for Pest Management, Molecular Siege and Surrender: Cuticle Degradation and Killing Tactics of Entomopathogenic Fungi against Insect Pests, Microbiome-disease dynamics in commercially mass reared insects, Physiological Impacts of Bee Viruses, and more.

  • Next-Generation Onco-Therapeutics

    • 1 Edición
    • Awanish Kumar + 1 más
    • Inglés
    Next-Generation Onco-Therapeutics explores the latest advancements in cancer treatment, focusing on personalized medicine and innovative therapeutic strategies. The book serves as a comprehensive resource for understanding how emerging technologies can reshape oncological care, providing insights into effective and compassionate patient management. Content explores cutting-edge developments in cancer therapies, featuring clinical examples and case studies that illustrate the practical application of new treatment modalities. It emphasizes the importance of integrative approaches that address the diverse needs of cancer patients, ensuring that healthcare professionals are equipped with the most current information in this rapidly evolving field. This book also addresses the urgent need for updated resources in oncological therapeutics, bridging the gap between traditional practices and modern innovations. By synthesizing diverse perspectives and evidence-based insights, it empowers healthcare providers, researchers, and policymakers to enhance treatment outcomes and improve patient well-being in the era of personalized medicine.

  • Autophagy – Part C

    • 1 Edición
    • Volumen 406
    • Inglés
    Autophagy, Part C, Volume 406 dives cellular housekeeping, weaving together the mechanistic precision of modern biology with the larger questions of health, aging, and resilience. Building on the foundations laid in Parts A and B, this book takes the reader from the microscopic machinery inside a single cell to the sweeping implications for organisms, ecosystems, and medicine. Chapters cover Lysosomal Function and Homeostasis: From Cellular Adaptation to Disease Pathogenesis, Autophagy Meets Plant Virology: From Molecular Crosstalk to Outstanding Challenges, Impact of mitophagy on obesity-affected tissues, Autophagy in Endothelial Cells: a gatekeeper of immune cell trafficking and function, and much more.Additional sections cover Viral Trafficking: The Role of Autophagy in the Release of Virus-Loaded Extracellular Vesicles and Sex matters in macroautophagy: sex-driven differences in autophagic function in aging and aging related-diseases.

  • Pharmacology of T-Cell Therapies

    • 1 Edición
    • Volumen 106
    • Inglés
    Pharmacology of T-Cell Therapies, Volume 106 in the Advances in Pharmacology series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Topics in this new release include Enhancing persistence of therapeutic T cells, T cell manufacturing impacts on in vivo function, Transient T cell therapies, In vivo T cell therapies, T cell subsets for therapy, Engineering T cell metabolism to enhance therapeutic efficacy, and Tracking Therapeutic T cells In Vivo contacts.

  • Lights on for the Nervous System: Exploring the Effects of Photobiomodulation - Part A

    • 1 Edición
    • Volumen 189
    • Inglés
    Lights on for the Nervous System: Exploring the Effects of Photobiomodulation: Part A, Volume 187 in the International Review of Neurobiology series, highlights new advances in understanding how light interacts with the human body and brain. This comprehensive volume presents chapters written by an international board of authors, covering the history and theory of therapeutic light use, the underlying mechanisms of light–cell interactions, and the systemic effects of light exposure. It explores cognitive enhancement, sleep regulation, and microbiome modulation, as well as the potential of light-based interventions for neurodegenerative disorders, chronic pain, traumatic brain injury, depression, and retinal diseases.Specific sections cover History of Humans Using Light, Theory of Light: Why Should It Work, Mechanisms of Light, Systemic Effects of Light, Light Application and Dosage, How Does Light Affect Brain Activity, Light Talks: The Role of Biophoton in Cellular Communication, Biophotons: Communication with Light, Light Effects on Brain Activity: Simulations/Dynamic Function, Cognitive Enhancement through Transcranial Infrared Laser Stimulation: Insights from Research, Light Effects on the Microbiome, Lights On for Sleep, Exploring the Effect of Red and Near Infrared Light on Neurodegenerative Disease, Light Effects on Parkinson's Disease: Intracranial Application, Light Effects on Parkinson's Disease: Transcranial Application, and much more.

  • Hypercortisolism: Diagnosis and Differential Diagnosis

    • 1 Edición
    • Volumen 132
    • Inglés
    Hypercortisolism: Diagnosis and Differential Diagnosis, Volume 132 presents a comprehensive series of chapters focused on the various aspects of endogenous hypercortisolism as contributed by an international team of specialists in endocrinology. Chapters in this new release include Cushing´s syndrome: Clinical presentation and associated comorbidities, Biochemical diagnosis of hypercortisolism: when and how?, ACTH independent Cushing syndrome: diagnosis and etiology, Bilateral macronodular and micronodular hyperplasia: biochemical, radiological and genetic diagnosis, Differential diagnosis between endogenous Cushing´s syndrome and pseudoCushing, and much more.Additional chapters delve into Differential diagnosis of ACTH dependent Cushing´s syndrome: hormonal and radiological studies, Ectopic Cushing´s syndrome: clinical presentation and diagnosis, Cyclic Cushing´s syndrome, Mild autonomous cortisol secretion: diagnosis, Cushing´s syndrome and pregnancy: clinical presentation and diagnosis, Molecular profile of Cushing´s syndrome, Cardiometabolic comorbidities in overt Cushing´s syndrome, and New tools for the diagnosis of hypercortisolism.

  • Biomechanics and Mechanobiology of Bone

    From Model to Patient
    • 1 Edición
    • Luis Cardoso + 2 más
    • Inglés
    Biomechanics and Mechanobiology of Bone: From Model to Patient provides readers with a comprehensive overview of the modelling and assessment of bone biomechanics. It addresses topics such as biosubstitutes and bone implants from the point of view of design, properties, computational modeling, and choice of biomaterials. It concentrates on the biomechanics and mechanobiology modeling approaches of bone, including biological models, multiphysical approaches, surface and volumetric growth models, and bone fluid flow models. This is augmented by case studies and examples of models for computer-aided diagnosis, treatment, and monitoring of bone diseases. Readers are introduced to bone physiology, adaptation, and disease, including cellular aspects at the root of bone mechanotransduction and leading to bone growth and remodeling, and management of diseases. Chapters also cover the mechanical, multiphysical multiscale properties of bone and constitutive laws including bone viscoelasticity, poroelasticity, bone damage, fatigue and fracture, as well as measurement techniques of bone properties.

  • Advances in Agronomy

    • 1 Edición
    • Volumen 198
    • Inglés
    Advances in Agronomy, Volume 198, the latest release in this leading reference on agronomy, contains a variety of updates and highlights new advances in the field, each written by an international board of authors.

  • Flavonoids Against Cancer Hallmarks

    • 1 Edición
    • Dharambir Kashyap + 1 más
    • Inglés
    Flavonoids Against Cancer Hallmarks provides an in-depth exploration of the anti-cancer potential of flavonoids and their ability to target key cancer hallmarks. The book encompasses a thorough analysis of flavonoids' sources, bioavailability, metabolic disposition, long-term safety, and adverse effects. It highlights the mechanisms through which flavonoids inhibit cancer growth and proliferation, focusing on their immunomodulatory, anti-angiogenic, anti-metastatic, and cell cycle inhibitory effects. Designed for oncology specialists, pharmacology and pharmacy students, cancer research scholars, and pharmaceutical industry researchers, this comprehensive guide also reviews recent cancer epidemiology and updates on existing therapeutic strategies.By detailing how flavonoids counteract cancer stemness and influence immune responses, this book offers innovative insights into utilizing plant-derived compounds for cancer treatment. It stands out by providing a detailed overview of flavonoids' cellular and molecular mechanisms while also evaluating the pros and cons of current therapeutic options, making it essential reading for a global audience.

  • Cellular Communication in Mammalian Germ-line Development

    • 1 Edición
    • Volumen 169
    • Inglés
    Cellular Communication in Development, Volume 169 provides a comprehensive overview of the intricate signaling pathways and molecular mechanisms that govern how cells communicate during the development of multicellular organisms. This volume explores the essential roles of cell-to-cell communication in processes such as embryogenesis, tissue patterning, organ formation, and differentiation. Specific chapters include Specification of pgcs, Establishing and maintaining gonadal cell fate, Role of retinoic acid in meiosis, Assembly of primordial follicles, Activation of primordial follicles, Mechanisms of germ-soma communication during follicular growth, Somatic regulation of oocyte meiotic arrest and resumption, Ovarian stroma/function/role in aging, and much more.Additional sections explore New approaches to supporting follicle growth/ovarian function in vitro, Cancer therapy - effects on survival/development of oocyte/follicle, Female germ cells from somatic cells, Spermatogenic stem cell niche, Role of macrophages in testis function, Male germ cells from somatic cells, and more.

  • Epigenetic Therapy by Phytochemicals in Lung Cancer

    Mechanisms, Therapeutic Potential, and Clinical Implications
    • 1 Edición
    • Umesh Kumar + 3 más
    • Inglés
    Epigenetic Therapy by Phytochemicals in Lung Cancer provides a comprehensive exploration of the intersection between cancer epigenetics and phytotherapy, focusing on lung cancer. The book emphasizes the role of epigenetic alterations in cancer progression and presents phytochemicals as promising agents capable of reversing these changes, thereby offering innovative therapeutic strategies. The content examines the mechanisms by which epigenetic modifications, such as DNA methylation and histone modification, contribute to lung cancer. It details specific phytochemicals—like curcumin, resveratrol, and quercetin—and their potential to modulate these pathways, while discussing clinical applications, challenges, and future research directions. For academics, this book equips researchers and healthcare professionals with evidence-based insights into alternative cancer therapies, enhancing understanding of multi-targeted approaches. It serves as a valuable reference for teaching and further research, promoting a more inclusive perspective in cancer care and addressing disparities in treatment access and efficacy.

  • Advances in Clinical Chemistry

    • 1 Edición
    • Volumen 133
    • Inglés
    Advances in Clinical Chemistry, Volume 133 in this ongoing series, examines physiologic and pathophysiologic biochemistry and their impacts on Clinical Chemistry testing and design. Molecular mechanisms of disease processes are highlighted in the context of traditional, current, and emerging technologies, and advances in the development of improved diagnostic and predictive biomarkers are examined, especially those targeting early and emerging diseases. Specific chapters in this new release include Drug Induced Renal Injury (DIRI) Biomarkers, Unveiling tobacco markers in exhaled breath, Advances in small extracellular vesicle analysis, Piezoelectric Sensors in Point-of-Care Testing, Mitochondrial myopathy biomarkers, and Hormonal and Metabolic Biomarkers in Long COVID.

  • Advances in Microbial Physiology

    • 1 Edición
    • Volumen 88
    • Inglés
    Advances in Microbial Physiology, Volume 88 explores the latest research and developments in microbial physiology, providing a comprehensive overview on how microorganisms function, adapt, and interact with their environments. This volume brings together leading experts to discuss fundamental processes such as metabolism, growth, gene regulation, signal transduction, stress responses, and cellular differentiation in bacteria, archaea, and fungi. Chapters cover Steroids as Antibacterials, From Feeding Cell to Fruiting Body: Multidrug Transport in the Life cycle of Dictyostelium discoideum, Evolution of xenobiotic catabolism, Glycyl-radical enzymes, How anaerobes cope with oxygen, and Extracellular Electron Transfer: From Early Life to Modern Biogeochemistry and Applications.

  • Non-Stationary and Nonlinear Data Processing for Automated Computer-Aided Medical Diagnosis

    • 1 Edición
    • Rajesh Kumar Tripathy + 3 más
    • Inglés
    Non-Stationary and Nonlinear Data Processing for Automated Computer-Aided Medical Diagnosis demonstrates the applications of machine learning and deep learning combined with signal processing techniques for human-machine interface applications using EMG signals. The book includes the analysis and classification of various heart diseases based on bio-signals like electrocardiogram (ECG), photoplethysmography (PPG), and phonocardiogram (PCG) signals. Various machine learning approaches, including advanced algorithms like multivariate signal processing, time-frequency analysis, and nonlinear signal processing are covered for CAD of neural, muscular, and cardiovascular diseases. The methods for CAD of various brain disorders are also included.Presented techniques utilize advanced non-stationary and nonlinear signal processing, along with machine learning and deep learning-based classification processes. CAD methods for diagnosing various neurological diseases are based on bio-signals such as electroencephalogram (EEG) and magnetoencephalogram (MEG), as well as medical images like magnetic resonance imaging (MRI) and computerized tomography (CT). Finally, the book addresses various types of medical signals and images, integrating nonlinear and non-stationary signal processing, machine learning, and deep learning within the CAD framework for diagnosing various diseases.

  • Yoga and Prevention of Type 2 Diabetes

    An Integrated Approach to Wellness
    • 1 Edición
    • S.V. Madhu
    • Inglés
    Yoga and Prevention of Type 2 Diabetes: An Integrated Approach to Wellness is a unique reference to approaching yoga, its principles, and how its various practices contribute to overall health and wellness and to understanding the scientific evidence and impact of yoga on glycemic control, insulin sensitivity, and stress reduction. The book lays the foundation to understanding the pathophysiology, epidemiology, and risk factors associated with type 2 diabetes while exploring the physiological and biochemical pathways by which yoga influences glucose metabolism and mitigates diabetes risk factors.Collectively... the book's chapters equip readers with a thorough understanding of Type 2 diabetes and the multifaceted role of yoga in its prevention and management. By combining theoretical knowledge with practical applications, this work will empower individuals and healthcare providers to take proactive steps toward better metabolic health through yoga.

  • Advances in Parasitology

    • 1 Edición
    • Volumen 131
    • Inglés
    This book explores the intersection of molecular biology, genomics, and ecology to redefine our understanding of parasitic organisms and their management. Beginning with the application of -omics research in platyhelminth parasites of fish, demonstrating how genomic and proteomic data are essential for understanding host-parasite dynamics and developing novel vaccines and treatments to support sustainable aquaculture. The focus then shifts to the complex internal ecosystems of parasites, and examining how their associated microbiomes—comprisi... bacteria, fungi, and viruses—influence parasite fitness, virulence, and host interactions. Finally, the book highlights the genus Entamoeba, delving into how how next-generation and long-read sequencing technologies have revolutionized the identification of cryptic species and improved epidemiological surveillance for pathogens like E. histolytica. Together, these chapters provide a modern framework for parasitology through the lens of advanced genetic tools and ecological integration.

  • Advances in Biomedical Engineering - Part A

    • 1 Edición
    • Volumen 402
    • Inglés
    Advances in Biomedical Engineering, Part A, Volume 402 provides a comprehensive overview of the latest developments, innovations, and research in the rapidly evolving field of biomedical engineering. This book covers a broad spectrum of topics, including medical imaging, biomaterials, tissue engineering, biomechanics, bioinstrumentation, and healthcare technologies. Specific chapters include Advances in biomedical engineering, Recent advances in nanomedicine as drug delivery systems, Advances in Nano biomaterials for Biomedical Engineering, Neurodiagnostic: Advances in diagnostic tools, Advances in Ferroptosis Research and Application, Bioink-based 3D Bioprinting: Paving the Path for Regenerative Medicine, and MRI Acute/Sub-Acute Ischemic Stroke Segmentation with Deep Learning: A Comprehensive Review.

  • Public Participation and Ethics Communication in Brain Research, Innovation, and Health

    • 1 Edición
    • Volumen 9
    • Inglés
    Public Engagement and Ethical Communication in Brain Research, Innovation, and Health, Volume Nine in the Developments in Neuroethics and Bioethics series, provides a comprehensive overview of various understandings of neuroscience and (neuro)ethics communication across research, policy, and society. Specific chapters in this new release include Neurohype Across Borders: How Media Narratives Shape Public Perception of Neurotechnology in English- and Spanish-Speaking Countries, Physicians’ Resistance Towards Pandemic Public Health Policies in Romania: Navigating Misinformation, Ethical Challenges, and Responsibility in Science Communication, Foresight Scenarios as Communicative Instruments in Anticipatory Neuroethics, and much more.Additional chapters include Draw closer to me: Participatory visual storytelling to include socio-cultural perspectives in neuroethics and policymaking, Against the Narrative of the Insufficiency of Human Rights on the Neurorights Discourse, Reflective accounts from collaborative neuro-oncology research: perspectives from patient partners and researchers, Responsible conceptualization in research and innovation, Anticipating Polarization: Public Discourse and the Unpreparedness of Neuroethics Communication, Shared Responsibility for Communicating Neuroscience Research: A Case Study for Spinal Cord Injury, and much more.Featured topics include creative and participatory approaches to (neuro)ethics communication, the impact of narratives on public perception and science policy, the importance of responsible communication in neuroscience, and the dynamics between patient partners and researchers. The volume also addresses cross-cultural perspectives and focuses on comparative case studies of current emerging neuroscience research and neurotechnologies across countries.

  • Intelligent Osteogenesis

    How A.I., New Materials, and Manufacturing Technologies Are Reshaping Bone Regeneration
    • 1 Edición
    • Carlo Galli
    • Inglés
    Intelligent Osteogenesis: How A.I., New Materials, and Manufacturing Technologies are Reshaping Bone Regeneration delves into the revolutionary intersection of technology and medicine. The book focuses on how cutting-edge advancements like artificial intelligence, nanotechnology, biotechnology, and material science significantly influence and transform bone regeneration therapies. It aims to shed light on the multifaceted nature of this field, bringing diverse elements together to reveal their collective impact. The book covers the use of A.I. to monitor advancements, the acceleration of research, and the technological influence on the application of bone regenerative techniques.Authored by experts, it serves as a definitive guide for both biomedical researchers and clinical practitioners in dentistry and orthopedics.

  • AI-enabled Sustainable Healthcare

    Demystifying Secure Quantum Blockchain
    • 1 Edición
    • M. Nivaashini + 4 más
    • Inglés
    AI-Enabled Sustainable Healthcare: Demystifying Secure Quantum Blockchain explores the convergence of quantum computing, blockchain technology, and artificial intelligence in the context of healthcare. In today's rapidly evolving technological landscape, traditional healthcare systems face challenges related to data security, interoperability, and the efficient utilization of patient information. The emergence of quantum computing, blockchain, and AI presents unprecedented opportunities to overcome these challenges and revolutionize healthcare delivery. This book provides a clear and accessible overview of these complex technologies and their potential applications in healthcare. By demystifying these concepts and illustrating their real-world implications, the book equips readers with the knowledge and insights needed to navigate the intersection of technology and healthcare effectively. Furthermore, as the demand for secure, transparent, and sustainable healthcare solutions continues to grow, there is an urgent need for informed discussions and innovative approaches in this field.

  • Human Microbiota for Skincare

    Sustainable, Innovative, and Personalized Skincare with Skin Microbiota
    • 1 Edición
    • Nar Singh Chauhan + 2 más
    • Inglés
    Human Microbiota for Skincare: Sustainable, Innovative, and Personalized Skin Care with Skin Microbiota explores the latest trends, innovations, and emerging research in microbiota-based skincare, positioning readers at the forefront of skincare advancements. It presents a global overview of current and future research, providing a comprehensive understanding of the skin microbiome and its potential applications in skincare. The book offers detailed insights into the interplay between the skin microbiome and human health, with chapters covering essential topics such as Personalized Skincare, Macroecological Dynamics of Skin Microbiota, Host-Microbe Interplay During Skin Diseases and Aging, Microbiome-Based Skin Care Formulations, and Ethical Regulations of Skin Therapies.This book consolidates datasets and real-life case studies, offering practical advice on incorporating microbiota-based products into daily routines and exploring future trends in microbiota-based skincare. Whether you are a scientist, researcher, or clinician, this book is an essential resource. It provides authoritative advice from experts in microbiology, dermatology, and biochemistry, facilitating multidisciplinary research and enhancing your ability to treat patients.

  • Protein Serine/Threonine Kinases in Neurodegenerative Disorders

    • 1 Edición
    • Heba Mohamed Mansour + 1 más
    • Inglés
    Protein Serine/Threonine Kinases in Neurodegenerative Disorders discusses protein kinase inhibitors and their potential role in modulating and treating neurodegenerative diseases. The book introduces protein kinases and inhibitors and includes detailed discussions on different types of kinases, including protein kinase C (PKC), AMP-activated protein kinase (AMPK), death-associated protein kinase 1 (DAPK1), cyclin-dependent kinases (CDKs), glycogen synthase kinases (GSKs), Rho-associated protein kinase (ROCK), microtubule affinity regulating kinases (MARKs), mammalian target of rapamycin (mTOR), leucine-rich repeat kinase 2 (LRRK2), PTEN-induced kinase 1 (PINK1), and dual-specificity tyrosine phosphorylation-regu... kinase (DYRK), and their roles in neurodegenerative disease, potential inhibitors, and therapeutic mechanisms.This book features 23 chapters written by renowned experts in the field of kinases. It explores novel targets modulated by protein kinases, including noncoding RNAs (ncRNAs) and mitogen-activated protein kinases (MAPKs) activated by tyrosine receptor kinases, and their roles in neurodegeneration. It also discusses the nexus between glycogen synthase kinases (GSKs) and glucagon-like peptide-1 receptor agonists (GLP-1RAs) and their role of metabolic regulation in neurodegeneration. The modulatory effects of protein kinase B (PKB/AKT) pathways in various neurodegenerative disorders, particularly Parkinson’s disease, are also examined. This book sheds light on bioactive compounds from natural products that target kinases and explains the role of different kinases in various pathogenic pathways and mechanisms involved in neurodegeneration, including regulated cell death, autophagy, synaptic dysfunction, and neuroinflammation.

  • Multifunctional Nano pharmaceuticals for Biomedical Applications

    • 1 Edición
    • Sushil K. Kashaw + 3 más
    • Inglés
    Multifunctional Nanopharmaceuticals for Biomedical Applications covers the latest advancements in multifunctional nanopharmaceuticals while also addressing the pressing need for innovative solutions for unmet medical challenges. Each chapter explores key topics such as the fundamentals of nanotechnology and drug delivery, PEGylated lipid carriers for cancer theranostics, and the latest in biomimetic nanomicells and nanorobots. With detailed discussions on design strategies, formulation techniques, and regulatory aspects, readers will gain a thorough understanding of the complexities and innovations in this dynamic field. The exploration of clinical applications and future trends also equips readers with the knowledge to navigate the evolving landscape of nanomedicine.This is an essential resource for researchers interested in the transformative potential of nanotechnology in drug delivery and disease treatment. It empowers readers to harness cutting-edge technologies for effective therapies, paving the way for a new era of personalized, precise, and potent medicine. With the rapid evolution of nanomedicine, this book serves as a crucial tool for researchers, students, healthcare professionals, and industry experts alike, bridging the gap between fundamental concepts and their real-world applications.

  • Cardiorespiratory Aspects of Duchenne Muscular Dystrophy

    New Perspectives and Controversies
    • 1 Edición
    • David J. Birnkrant
    • Inglés
    Cardiorespiratory Aspects of Duchenne Muscular Dystrophy: New Perspectives and Controversies is designed to address key challenges in the field by providing a cardiorespiratory perspective on clinical care, drug development, and the regulatory approval of new drugs. The book discusses current achievements and limitations of care and addresses clinical challenges. It offers a detailed, critical examination of the drug development process and identifies potential flaws in current regulatory processes. Novel recommendations for improving study methodologies and regulatory decisions are discussed, with the goal of enabling more effective drugs to reach individuals with Duchenne Muscular Dystrophy (DMD).This book is designed to provide important and interesting information to a variety of stakeholders, including clinicians, researchers, and regulators, as well as patients and their caregivers. Clinicians will find a summary of standards of care and strategies to overcome the challenges they are likely to face in enacting those standards. Researchers will gain insights into the crucial importance of cardiorespiratory outcome measures and find recommendations designed to improve study methodologies. Regulators will benefit from an examination of potential flaws in the current drug approval process and from proposed recommendations aimed at ensuring that approved drugs are truly effective. The goal of this comprehensive approach is to enhance the outcomes and survival of individuals with DMD by focusing on key determinants of cardiorespiratory health.

  • Biochar Applications

    Advances in Environmental Remediation and Resource Recovery
    • 1 Edición
    • Ahmad Hussaini Jagaba + 4 más
    • Inglés
    Biochar Applications: Advances in Environmental Remediation and Resource Recovery provides a combined approach between environmental science and environmental engineering that involves the improvement of the natural environment, or the remediation, of polluted sites. In addition, it discusses bioprocess engineering, including the synthesis, modification, characterization, and management of biochar from biomass waste materials. The book includes coverage on sources, impacts, and applications of biochar that could potentially be used as catalysts to enhance environmental remediation and resource recovery processes. Examples of applied research that demonstrate the relationship between wastewater, soil, contaminated environments, remediation, resource recovery, sustainability, and circular bioeconomy are also included.The book bridges the gap between biochar applications in wastewater treatment, soil improvement, gas mitigation, and resource recovery.

  • Targeting DNA Repair Mechanisms, Tumor Genetics, and Signaling Pathways

    Synergistic Approaches in Gastrointestinal Cancer Treatment
    • 1 Edición
    • Ganji Purnachandra Nagaraju + 1 más
    • Inglés
    Targeting DNA Repair Mechanisms, Tumor Genetics, and Signaling Pathways: Synergistic Approaches in Gastrointestinal Cancer Treatment provides a comprehensive exploration of the complex mechanisms underlying gastrointestinal (GI) cancers, including colorectal, gastric, liver, and pancreatic malignancies. The book addresses the urgent need for innovative therapeutic strategies by synthesizing current research on DNA repair, tumor genetics, and cellular signaling pathways critical to cancer progression and treatment. It examines the roles of DNA repair mechanisms and the influence of genetic factors on personalized medicine while also discussing the potential of combining targeted therapies to enhance treatment efficacy. Featuring real-world case studies and insights from leading experts, the book bridges the gap between basic research and clinical application. For an academic audience, this resource promotes a holistic understanding of GI cancer biology, addresses treatment resistance, and fosters collaboration among researchers and clinicians, ultimately improving patient outcomes in this rapidly evolving field.

  • Computational Approaches to Natural Products Discovery

    • 1 Edición
    • Volumen 730
    • Inglés
    Computational Approaches to Natural Products Discovery, Volume 720 provides descriptions of the latest techniques in computational methods for the study of natural products. Techniques covered are related to genome mining, natural product biosynthesis, natural product evolution, and natural product structure. Chapters in this new release cover Prediction of natural product bioactivity from BGC sequence to guide genome mining efforts, Genome mining for resistance genes to identify bioactive natural products with ARTS, Predicting lasso peptide structure with LassoPred, Predicting lanthipeptide structure with Rosetta, Using lsaBGC to investigate BGC Evolution, and an Analysis of BGC evolution with CORASON.

  • Emerging Diagnostic Glucose Sensing Approaches

    Diabetes
    • 1 Edición
    • Abhishek Kandwal + 2 más
    • Inglés
    Emerging Diagnostic Glucose Sensing Approaches surveys past and recent work on non-invasive blood glucose monitoring. The book highlights two complementary paths: electromagnetic-wave... sensing, using physical models and advanced sensors to measure glucose non-invasively; and physiological techniques (ECG/EEG) integrated with artificial intelligence and deep learning to infer glucose levels. It discusses how physical models, biomedical methodologies, and engineering prototyping enable accurate analysis and device development. With a focus on breakthroughs in electromagnetic sensors and non-invasive research, this volume serves as a foundational reference for biomedical researchers and engineers pursuing next-generation glucose monitoring.

  • Fruit Seeds and Peels for Sustainable Biomaterials

    • 1 Edición
    • Sneh Punia Bangar + 1 más
    • Inglés
    Fruit Seeds and Peels for Sustainable Biomaterials explores the utilization of fruit and vegetable waste in the production of bioplastics as environmentally friendly alternatives to conventional petroleum-based plastics. The book presents innovative approaches to reducing the carbon footprint of the packaging industry while advancing principles of recyclability, sustainability, and the circular economy.The chapters provide an in-depth examination of various waste valorization techniques and compile global research efforts focused on the transformation of various fruit processing by-products. These industrial wastes are rich in polysaccharides, such as cellulose, hemicellulose, and lignin, which can be further treated to synthesize nanocellulose crystals or fibers using different physicochemical and nonconventional methods.The book highlights the application of these biomaterials in packaging, offering food professionals and other stakeholders sustainable alternatives to traditional plastic polymers. It delivers comprehensive insights into the potential of fruit seeds as a renewable source of biomaterials, and presents valuable scientific information on the technologies involved in using bio-based materials for food preservation. These insights aim to reduce the use of non-biodegradable plastic packaging materials.

  • Immunomodulators Part B

    • 1 Edición
    • Volumen 152
    • Inglés
    Immunomodulators Part B brings together a curated set of research-focused chapters that explore how the immune system is influenced by microbes, immune checkpoint molecules, genetic regulation, and emerging therapeutic strategies. It covers the role of the microbiome and microbial products in shaping immune responses relevant to gastrointestinal cancers, examines VISTA as a “double-edged” checkpoint in cancer and autoimmunity, and uses bioinformatics to uncover immune-modulatory patterns in HPV-associated head and neck squamous cell carcinoma and bladder cancer.

  • Advances in Immunology

    • 1 Edición
    • Volumen 168
    • Inglés
    Advances in Immunology, Volume 168, the latest release in a long-established and highly respected publication, presents current developments and comprehensive reviews in immunology. Sample topics in this new release include Alarmins in mucosal tissues and how they regulate health and disease, and more.

  • Artificial Intelligence for Multi-omics Analysis Part B

    • 1 Edición
    • Volumen 222
    • Inglés
    Artificial Intelligence for Multi-omics Analysis Part B, Volume 222 in the Progress in Molecular Biology and Translational Science series, highlights recent advances, with this new volume presenting chapters on a variety of topics, including Artificial Intelligence in multi-omics analysis of small molecule drug discovery, AI in multi-omics analysis in antimicrobial resistance, Artificial Intelligence and multi-Omics Approach in Vaccine Development, Artificial Intelligence in multi-omics Analysis of heart diseases, Artificial Intelligence in multi-omics Analysis of Kidney Diseases, Artificial Intelligence in multi-omics Analysis of Gastrointestinal Diseases, AI in multi-omics analysis in Stem cell research, and AI in multi-omics analysis in cancer, and more.Additional sections cover AI in multi-omics analysis in obstructive lung diseases, AI in multi-omics analysis in neurodiseases, AI in multi-omics analysis in autoimmune diseases, AI in multi-omics analysis of liver diseases, AI in multi-omics analysis of COVID-19 patient data, and AI in multi-omics analysis of Type 2 diabetes.

Temas relacionados