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Elsevier

Libros en Ciencias de la Vida

  • EEG-Based Brain-Computer Interfaces

    Cognitive Analysis and Control Applications
    • 1 Edición
    • Dipali Bansal + 1 más
    • Inglés
    EEG-Based Brain-Computer Interface: Cognitive Analysis and Control Applications provides a technical approach to using brain signals for control applications, along with the EEG-related advances in BCI. The research and techniques in this book discuss time and frequency domain analysis on deliberate eye-blinking data as the basis for EEG-triggering control applications. In addition, the book provides experimental scenarios and features algorithms for acquiring real-time EEG signals using commercially available units that interface with MATLAB software for acquisition and control.

  • Genes, Brain Function, and Behavior

    What Genes Do, How They Malfunction, and Ways to Repair Damage
    • 1 Edición
    • Douglas Wahlsten
    • Inglés
    Genes, Brain Function, and Behavior offers a concise description of the nervous system that processes sensory input and initiates motor movements. It reviews how behaviors are defined and measured, and how experts decide when a behavior is perturbed and in need of treatment. Behavioral disorders that are clearly related to a defect in a specific gene are reviewed, and the challenges of understanding complex traits such as intelligence, autism and schizophrenia that involve numerous genes and environmental factors are explored. New methods of altering genes offer hope for treating or even preventing difficulties that arise in our genes. This book explains what genes are, what they do in the nervous system, and how this impacts both brain function and behavior.

  • Handbook of Sleep Disorders in Medical Conditions

    • 1 Edición
    • Josee Savard + 1 más
    • Inglés
    Handbook of Sleep Disorders in Medical Conditions reviews the current knowledge on the nature and manifestations of sleep disorders associated with a variety of common medical conditions, including epilepsy, traumatic brain injury and dementia. It also provides clinical guidelines on how to assess and treat them with pharmacological and non-pharmacological interventions. Although the general principles of sleep medicine may be applied to some extent to patients with comorbid medical conditions, this book makes the case that an adaptive approach is warranted when considering the particularities of each condition. In addition, clinicians must also be cautious when prescribing sleep medications as some pharmacological agents are known to exacerbate symptoms associated with the medical condition, such as cognitive deficits (i.e. difficulties with memory and attention) in cancer patients experiencing chemo brain, or in persons with neurologic conditions (e.g. mild cognitive impairment, dementia, stroke, brain injury). A differential approach to evaluating and treating sleep is thus warranted.

  • Ecometabolomics

    Metabolic Fluxes versus Environmental Stoichiometry
    • 1 Edición
    • Sumira Jan + 1 más
    • Inglés
    Ecometabolomics: Metabolic Fluxes versus Environmental Stoichiometry focuses on the interaction between plants—particularly plants that have vigorous secondary metabolites—and the environment. The book offers a comprehensive overview of the responses of the metabolome of organisms to biotic and abiotic environmental changes. It includes an introduction to metabolomics, summaries of metabolomic techniques and applications, studies of stress in plants, and insights into challenges. This is a must-have reference for plant biologists, plant biochemists, plant ecologists and phytochemists researching the interface between plants and the environment using metabolomics.

  • Platelets

    • 4 Edición
    • Alan D. Michelson + 3 más
    • Inglés
    Platelets, Fourth Edition, integrates the entire field of platelet biology, pathophysiology, and clinical medicine with contributions from 142 world experts from 18 countries. This award-winning reference provides clear presentations by basic scientists on the cellular, molecular, and genetic mechanisms of platelets and the role of platelets in thrombosis, hemorrhage, inflammation, antimicrobial host defense, wound healing, angiogenesis and cancer. It also provides start-of-the-art presentations by hematologists, cardiologists, stroke physicians, blood bankers, pathologists and other clinicians on platelet function testing, disorders of platelet numbers and function, antiplatelet therapy and therapy to increase platelet numbers and/or function. Since the publication of the Third Edition of Platelets, there has been a rapid expansion of knowledge in both basic biology of platelets and the clinical approach to platelet-related diseases. This Fourth Edition of Platelets draws all this information into a single, comprehensive and authoritative resource.

  • Ubiquitin and Ubiquitin-like Protein Modifiers

    • 1 Edición
    • Volumen 618
    • Inglés
    Ubiquitination and Protein Stability - Part A Volume 618, the latest release in the Methods in Enzymology series, highlights new advances in the field, with this updated volume presenting interesting chapter written by an international board of authors. Topics of note in this new release include the Preparation of ubiquitinated nucleosomes with native and non-hydrolyzable linkages, Methods to measure ubiquitin chain length and linkage, Genetic approaches to study the yeast ubiquitin system, Enzymatic preparation of monoubiquitinated proteins, Methods to distinguish the function of ubiquitin in autophagy and the proteasome pathway, the Purification and characterization of enzyme activity of USPs, and much more.

  • Anorectal Disorders

    Diagnosis and Non-Surgical Treatments
    • 1 Edición
    • Enrique Coss-Adame + 1 más
    • Inglés
    Anorectal Disorders: Diagnosis and Nonsurgical Treatments incorporates the most recent major advances in the understanding of anal and rectal anatomy to provide clinical evidence of care for those suffering from anorectal disorders. By condensing basic and practical aspects in the knowledge of anorectal disorders, this book provides a comprehensive review of the anatomy and physiology of the anorectal region. It includes new technology that expands and modifies current perceptions about the functional anatomy of the anorectal region and ultimately impacts how we conceive muscle and nerve structures functioning together to maintain fecal continence and properly execute the process of defecation. Perfect for medical researchers, gastroenterologists, general practitioners, internal medicine doctors and general surgeons, this title will provide diagnosis and treatment options for all patients suffering from anorectal disorders.

  • Non-alcoholic Beverages

    Volume 6. The Science of Beverages
    • 1 Edición
    • Alexandru Grumezescu + 1 más
    • Inglés
    Nonalcoholic Beverages, Volume Six in The Science of Beverages series, offers a wide-range of knowledge and expertise from research professionals around the world. The book focuses on the research and development of innovative products and new growing trends based on consumer demand for natural drinks that have health benefits. The book discusses the properties and benefits of developing nonalcoholic beverages, their production particularities, associated properties, physiochemical characteristics, and methods to help researchers and students learn about utilized nonalcoholic beverages.

  • Molecular Biology Techniques

    A Classroom Laboratory Manual
    • 4 Edición
    • Sue Carson + 3 más
    • Inglés
    Molecular Biology Techniques: A Classroom Laboratory Manual, Fourth Edition is a must-have collection of methods and procedures on how to create a single, continuous, comprehensive project that teaches students basic molecular techniques. It is an indispensable tool for introducing advanced undergraduates and beginning graduate students to the techniques of recombinant DNA technology—or gene cloning and expression. The techniques used in basic research and biotechnology laboratories are covered in detail. Students will gain hands-on experience on subcloning a gene into an expression vector straight through to the purification of the recombinant protein.

  • Fermented Beverages

    Volume 5. The Science of Beverages
    • 1 Edición
    • Alexandru Grumezescu + 1 más
    • Inglés
    Fermented Beverages, Volume Five, the latest release in The Science of Beverages series, examines emerging trends and applications of different fermented beverages, including alcoholic and non-alcoholic drinks. The book discusses processing techniques and microbiological methods for each classification, their potential health benefits, and overall functional properties. The book provides an excellent resource to broaden the reader’s understanding of different fermented beverages. It is ideal for research and development professionals who are working in the area of new products.

  • Comprehensive Overview of Modern Surgical Approaches to Intrinsic Brain Tumors

    • 1 Edición
    • Kaisorn Chaichana + 1 más
    • Inglés
    Comprehensive Overview of Modern Surgical Approaches to Intrinsic Brain Tumors addresses limitations in the scientific literature by focusing primarily on surgical approaches to various intrinsic neoplasms using diagrams and step-by-step instructions. It provides the advantages and disadvantages of these approaches, controversies, and technical considerations and discusses topics such as anatomy, pathology and animal models, imaging, open brain tumor approaches and minimally invasive approaches. Additionally, it discusses controversial treatments and the pros and cons of each. This book is a valuable source for medical students, neurosurgeons and any healthcare provider who has an interest in brain tumors and techniques to treat them.

  • Neural Stem Cells and Adult Neurogenesis

    • 1 Edición
    • Arie S. Mobley
    • Inglés
    Neural Stem Cells and Adult Neurogenesis provides graduate students and neuroscientists with a basic understanding of what neural stem cells are and the cell types they produce. This early graduate level reference describes their physiology and potential for medicine and provides students with fundamental stem cell information. An overview of stem cell sources in the human body and a brief mention of relevant diseases provide context for the value of this knowledge. The book also includes chapters on induced pluripotent stem cells (iPSCs), the methods used to obtain them, and a review of the ethical challenges associated with stem cell research. For each region, the book provides a description of its neurogenic niche, cellular and molecular biology, and information on the neurons’ contribution to normal and diseased brain function. The level of information is appropriate for early graduate students, introducing technology and molecular biology in an accessible format.

  • Nucleic Acid Nanotheranostics

    Biomedical Applications
    • 1 Edición
    • Marco Filice + 1 más
    • Inglés
    Nucleic Acid Nanotheranostics: Biomedical Applications offers a comprehensive overview of improvements and new trends in fabrication of nanostructures as theranostic multifunctional carriers in gene therapy. With a strong focus on medical applications (comprising diagnosis, therapy and imaging), the book also examines gene therapy in an individual patient’s cells or tissues to treat genetic diseases. Sections cover Biomedical and Diagnostic applications of Nucleic Acids, Biologic and Synthetic Advanced Nanostructures for nucleic acid delivery, and important considerations of nanomedicine. This book is a valuable guide for materials scientists, physicians, chemists and engineers, but is also ideal for clinicians wishing to expand their knowledge.

  • Flour and Breads and Their Fortification in Health and Disease Prevention

    • 2 Edición
    • Victor R. Preedy + 1 más
    • Inglés
    Flour and Breads and Their Fortification in Health and Disease Prevention, Second Edition, presents the healthful benefits of flours and flour products and guides the reader on how to identify opportunities for improving health through the use of flour and fortified flour products. The book examines flour and bread related agents that affect metabolism and other health-related conditions, explores the impact of compositional differences between flours, including differences based on country of origin and processing technique, and includes methods for the analysis of flours and bread-related compounds in other foods. This revised, updated edition contains new research on diverse flours with an emphasis on nutrients and nutraceuticals as supplements, thus making this content a timely reference for both nutritionists and food scientists.

  • Breaking Tolerance to Pancreatic Cancer Unresponsiveness to Chemotherapy

    • 1 Edición
    • Volumen 5
    • Inglés
    Breaking Tolerance to Pancreatic Cancer Unresponsiveness to Chemotherapy edited by Dr. Nagaraju, PhD., DSc. focuses on overriding the resistance from chemotherapeutic drugs with a broader range of treatment options. It particularly focuses on stroma, tumor microenvironment, stem cells, stellate cells, transcription factors, growth factors, and important signaling pathways. This volume discusses topics such as pancreatic cancer biology, current therapeutic options, EMT, chemotherapy resistance mechanisms, and genetic manipulations and natural products to enhance the sensitivity of pancreatic cancer to chemotherapy. Additionally, it discusses small targeted molecules and pancreatic cancer trials, and nanotechnology-based drug delivery.Breaking Tolerance to Pancreatic Cancer Unresponsiveness to Chemotherapy is a valuable source for researchers and advanced students in cancer and oncology as well as clinicians and medical students who are interested in learning more about ways to break pancreatic cancer resistance to chemotherapy.

  • Genetic Breeding and Molecular Marker-Assisted Selective Breeding of Largemouth Bass

    • 1 Edición
    • Bai Junjie + 1 más
    • Inglés
    Genetic Breeding and Molecular Marker-Assisted Selective Breeding of Largemouth Bass provides evidenced-based research that summarizes the theory and practice of genetic breeding. It provides a theoretical basis and technical support for the genetic improvement of largemouth bass varieties, but is also a good reference on the genetic breeding of other farmed fish. As knowledge of systematic studies, including germplasm resources, biology, quantitative genetics, selection breeding, variety hybridization and molecular marker assisted breeding is needed to increase growth performance, this book provides comprehensive information that is suitable for aquatic genetic breeding researchers and undergraduate and graduate students in aquatic genetics and breeding.

  • Nucleic Acid Sensing and Immunity, Part A

    • 1 Edición
    • Volumen 344
    • Inglés
    Nucleic Acid Sensing and Immunity - PART A, Volume 344, provides a comprehensive overview of the nucleic acid machinery, from plants to mammalians, as well as their regulation. Specific chapters in this updated release include Molecular bases of discrimination between self from non-self nucleic acids, Intracellular RNA sensing in mammalian cells, Nuclear DNA damage and nucleic acid sensing, Negative regulation of nucleic acid sensing, Dendritic cell responses to exogenous nucleic acids, Activating the nucleic acid-sensing machinery for anticancer immunity, and Nucleic acid sensing and inflammasomes, amongst other topics.

  • Iron Metabolism: Hepcidin

    • 1 Edición
    • Volumen 110
    • Gerald Litwack
    • Inglés
    Iron Metabolism, Volume 110, the latest release in the Vitamins and Hormones series first published in 1943, covers the field of hormone action, vitamin action, X-ray crystal structure, physiology and enzyme mechanisms, with this release focusing on topics relating to hepcidin, bacterial infection, and iron overload, the role of heparan sulfates in hepcidin regulation, hepcidin CDNA and human gene sex hormones, growth factors and hepcidin, HFE gene polymorphisms and hereditary hemochromatosis, hepcidin and il-1beta, hepcidin-ferroportin axis, cardiomyocyte hepcidin, adipocyte iron, leptin and hepcidin, regulators of hepcidin expression, and much more.

  • Advances in Applied Microbiology

    • 1 Edición
    • Volumen 106
    • Geoffrey M. Gadd + 1 más
    • Inglés
    Advances in Applied Microbiology, Volume 106, continues the comprehensive reach of this widely read and authoritative review source in microbiology. Users will find invaluable references and information on a variety of areas, with this updated volume including chapters covering The role and regulation of the stress activated sigma factor SigB in the saprophytic and host-associated life stages of the pathogen Listeria monocytogenes, Bacterial synthesis of Se nanoparticles, Siderophores in environmental research, Methods to reduce spoilage and microbial contamination of plant produce, Nitrogen cycling during wastewater treatment, Oxalic acid, a molecule at crossroads of bacterial-fungal interactions, and Bacterial spores, from ecology to biotechnology.

  • Malignant Pleural Mesothelioma

    A Guide for Clinicians
    • 1 Edición
    • Antonio Giordano + 1 más
    • Inglés
    Malignant Pleural Mesothelioma: A Guide for Clinicians is a practical book developed to assist clinicians, pathologist and molecular biologist in the management of malignant pleural mesothelioma (MPM). MPM represents a challenge in terms of diagnosis, staging and treatment, and to date, the optimal management of MPM patients has not yet been clearly defined – and this book is intended to be an efficient tool for these cases. The book encompasses topics such as epidemiology and surveillance evidence, multimodality imaging assessment of MPM, pathology, molecular mechanisms and treatment of such disease. Additionally, it discusses the standard operative procedures and the future directions for the management of MPM from experts’ experiences. Malignant Pleural Mesothelioma: A Guide for Clinicians is a valuable source for oncologists, pathologist, cancer researchers, thoracic specialists and several members of biomedical field who needs to learn more from experts about the diagnosis, operative procedures and treatment of malignant pleural mesothelioma.

  • Advances in Clinical Chemistry

    • 1 Edición
    • Volumen 89
    • Gregory S. Makowski
    • Inglés
    Advances in Clinical Chemistry, Volume 89, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. The serial discusses the latest and most up-to-date technologies related to the field of clinical chemistry, and is the benchmark for novel analytical approaches in the clinical laboratory.

  • Basic and Applied Bone Biology

    • 2 Edición
    • David B. Burr + 1 más
    • Inglés
    Basic and Applied Bone Biology, Second Edition, provides an overview of skeletal biology, from the molecular level, to the organ level, including cellular control, interaction and response, adaptive responses to various external stimuli, and the interaction of the skeletal system with other metabolic processes in the body. The book includes chapters that address how the skeleton can be evaluated through the use of various imaging technologies, biomechanical testing, histomorphometric analysis, and the use of genetically-modified animal models. Each chapter delves deep into the important details of topics covered to provide a solid understanding of the basics of bone biology. Bone biology researchers who also train undergraduate and graduate students in the lab will use this book constantly to orient new students on the basics of the field and as a background reference for many of the technical aspects of qualification in bone biology (e.g., mechanics, histomorphometry, genetic modification, biochemistry, etc.).

  • Organ Development

    • 1 Edición
    • Volumen 132
    • Inglés
    Organ Development, Volume 132, the latest release in the Current Topics in Developmental Biology series, highlights new advances in the field, with this new volume presenting interesting chapter written by an international board of authors. This volume highlights cogent reviews of the development, maintenance and regeneration/repair of several organ systems, from eye to kidney, to the musculoskeletal system. Many reviews highlight new techniques or technologies that are currently pushing the field. The role of both embryonic and adult stem cells are highlighted and senior authors are all women scientists.

  • DNA Repair

    • 1 Edición
    • Volumen 115
    • Inglés
    DNA Repair, Volume 115, the latest release in the Advances in Protein Chemistry and Structural Biology series, provides an overview of current developments in mechanisms underlying DNA repair, their involvement in maintaining chromatin repair, the balance between chromosome breaks repair pathways, tumorigenesis, immune signaling and infection-induced inflammation. Specific chapters cover the Structure and function of the multi-subunit TFIIH with insights into nucleotide excision repair, Chromatin repair: how DNA packaging controls double-strand break repair, Controlling the balance between chromosome breaks repair pathways, The targeting of DNA repair pathways in the era of precision oncology, and much more.

  • Metabolons and Supramolecular Enzyme Assemblies

    • 1 Edición
    • Volumen 617
    • Inglés
    Metabolons and Supramolecular Enzyme Assemblies, Volume 617 in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics, including Dynamic plant metabolons, TCA cycle metabolons, the Chemotactic assembly of metabolons, Repurposing peroxisomes for metabolic engineering, Repurposing yeast mitochondria for metabolic engineering, Repurposing plant compartments for metabolic engineering, Protein scaffolds for pathway co-localization on lipid droplets, Engineered enzyme assemblies for metabolic engineering, NRPS assembly lines and P450 interactions, and much more.

  • Bioarchaeology of Marginalized People

    • 1 Edición
    • Madeleine L. Mant + 1 más
    • Inglés
    Bioarchaeology of Marginalized People amplifies the voices of marginalized or powerless individuals. Following previous work done by physical anthropologists on the biology of poverty, this volume focuses on the voices of past actors who would normally be subsumed within a cohort or whose stories represent those of the minority. The physical effects of marginalization – manifest as skeletal markers of stress and disease – are read in their historical contexts to better understand vulnerability and the social determinants of health in the past. Bioarchaeological, archaeological, and historical datasets are integrated to explore the varied ways in which individuals may be marginalized both during and after their lifespan. By focusing on previously excluded voices this volume enriches our understanding of the lived experience of individuals in the past. This volume queries the diverse meanings of marginalization, from physical or social peripheralization, to identity loss within a majority population, to a collective forgetting that excludes specific groups. Contributors to the volume highlight the histories of individuals who did not record their own stories, including two disparate Ancient Egyptian women and individuals from a high-status Indigenous cemetery in British Columbia. Additional chapters examine the marginalized individuals whose bodies comprise the Robert J. Terry anatomical collection and investigate inequalities in health status in individuals from Canada, the United States, and the United Kingdom. Modern clinical population health research is examined through a historical lens, bringing a new perspective to the critical public health interventions occurring today. Together, these papers highlight the role that biological anthropologists play both in contributing to and challenging the marginalization of past populations.

  • Gap Junction Structure and Chemical Regulation

    Direct Calmodulin Role in Cell-to-Cell Channel Gating
    • 1 Edición
    • Camillo Peracchia
    • Inglés
    Gap Junction Structure and Chemical Regulation: Direct Calmodulin Role in Cell-to-Cell Channel Gating describes and discusses the findings of major studies conducted during the past century on the structure and chemical regulation of direct cell-to-cell communication via gap junction channels. Chapters bring together important findings on direct cell communication, from its history, to its structure and regulation. These channels are essential for normal organ function, and mutations in their protein (connexin) cause various diseases. The book is useful for established investigators who need a review on the field and young investigators who need a thorough resource for study and comprehension.

  • Echinoderms

    • 1 Edición
    • Volumen 150
    • Inglés
    Echinoderms, Volume 150 in the Methods in Cell Biology series, highlights new advances in the field, with this update presenting interesting chapters on procuring animals and culturing of eggs and embryos, cryopreservation of sea urchin gametes, emerging echinoderm models, culturing of sand dollars, cidaroids and heart urchins, culturing echinoderm larvae through metamorphosis, microinjection methods, injection of exogenous messages and protein overexpression, blastomere transplantation, visualization of embryonic polarity, larval immune cell approaches, methods for analysis of sea urchin primordial germ cells, and protocols and best practices for toxicology and pH studies using echinoderms and　several new chapters outlining the use of sea urchins in the classroom.

  • Bottled and Packaged Water

    Volume 4: The Science of Beverages
    • 1 Edición
    • Alexandru Grumezescu + 1 más
    • Inglés
    Bottled and Packaged Water, Volume Four in The Science of Beverages series, offers great perspectives on current trends in drinking water research, quality control techniques, packaging strategies, and current concerns in the field, thus revealing the most novel standards in the industry. As consumer demand for bottled and packaged water has increased, the need for scientists and researchers to understand how to analyze water quality, safety, and control are essential. This all-encompassing resource for research and development in this flourishing field covers everything from sensory and chemical composition, to materials and manufacturing.

  • Modeling and Control of Infectious Diseases in the Host

    With MATLAB and R
    • 1 Edición
    • Esteban A. Hernandez-Vargas
    • Inglés
    Modeling and Control of Infectious Diseases in the Host: With MATLAB and R provides a holistic understanding of health and disease by presenting topics on quantitative decision-making that influence the development of drugs. The book presents modeling advances in different viral infections, dissecting detailed contributions of key players, along with their respective interactions. By combining tailored in vivo experiments and mathematical modeling approaches, the book clarifies the relative contributions of different underlying mechanisms within hosts of the most lethal viral infections, including HIV, influenza and Ebola. Illustrative examples for parameter fitting, modeling and control applications are explained using MATLAB and R.

  • Biomarkers in Toxicology

    • 2 Edición
    • Ramesh C. Gupta
    • Inglés
    Biomarkers in Toxicology, Second Edition, is a timely and comprehensive reference dedicated to all aspects of biomarkers that relate to chemical exposure and their effects on biological systems. This revised and completely updated edition includes both vertebrate and non-vertebrate species models for toxicological testing and the development of biomarkers. Divided into several key sections, this reference volume contains new chapters devoted to topics in microplastics, neuroimmunotoxicity and nutraceuticals, along with a look at the latest cutting-edge technologies used to detect biomarkers. Each chapter contains several references to current literature and important resources for further reading. Given this comprehensive treatment, this book is an essential reference for anyone interested in biomarkers across the scientific and biomedical fields.

  • In Silico Drug Design

    Repurposing Techniques and Methodologies
    • 1 Edición
    • Kunal Roy
    • Inglés
    In Silico Drug Design: Repurposing Techniques and Methodologies explores the application of computational tools that can be utilized for this approach. The book covers theoretical background and methodologies of chem-bioinformatic techniques and network modeling and discusses the various applied strategies to systematically retrieve, integrate and analyze datasets from diverse sources. Other topics include in silico drug design methods, computational workflows for drug repurposing, and network-based in silico screening for drug efficacy. With contributions from experts in the field and the inclusion of practical case studies, this book gives scientists, researchers and R&D professionals in the pharmaceutical industry valuable insights into drug design.

  • EEG Brain Signal Classification for Epileptic Seizure Disorder Detection

    • 1 Edición
    • Sandeep Kumar Satapathy + 3 más
    • Inglés
    EEG Brain Signal Classification for Epileptic Seizure Disorder Detection provides the knowledge necessary to classify EEG brain signals to detect epileptic seizures using machine learning techniques. Chapters present an overview of machine learning techniques and the tools available, discuss previous studies, present empirical studies on the performance of the NN and SVM classifiers, discuss RBF neural networks trained with an improved PSO algorithm for epilepsy identification, and cover ABC algorithm optimized RBFNN for classification of EEG signal. Final chapter present future developments in the field. This book is a valuable source for bioinformaticians, medical doctors and other members of the biomedical field who need the most recent and promising automated techniques for EEG classification.

  • Therapeutic Application of Nitric Oxide in Cancer and Inflammatory Disorders

    • 1 Edición
    • Lucia Morbidelli + 1 más
    • Inglés
    Therapeutic Application of Nitric Oxide in Cancer and Inflammatory Disorders presents updated reviews on the chemistry, signaling, pre-clinical and clinical activities on the role of nitric oxide donors/inhibitors used alone and in combination with other therapeutic agents for the treatment of a variety of diseases. This book examines various studies related to the application of novel therapeutic NO (donors/inhibitors) compounds in the treatment of various cancers. These studies have been shown to exert significant therapeutic activities against various cancers and various inflammatory diseases such as rheumatoid arthritis, Crohn’s disease, allergies, and asthma, where no current effective therapies exist. Pathologies based on functional and structural vascular alterations are also taken into consideration. Edited and written by internationally renowned experts in the field of novel therapeutics for cancer, this book is a valuable source for cancer researchers, medical scientists, clinicians, clinical pharmacologists, and graduate students.

  • Introductory Immunology

    Basic Concepts for Interdisciplinary Applications
    • 2 Edición
    • Jeffrey K. Actor
    • Inglés
    Introductory Immunology: Basic Concepts for Interdisciplinary Applications, Second Edition is a completely updated, revised and expanded resource on the immune system as a primary defense for the maintenance of health and homeostasis. The book highlights the components of the human immune system and how they work together to confer protection against pathogenic invaders. It also creates an understanding of the basis for clinical tests and immune therapeutics and their importance in identifying and treating disease states. This updated edition will strengthen the foundation required to understand the placement of immune function within clinical practice, thus allowing a basic platform to define therapeutic treatments.

  • Key Productivity and Performance Strategies to Advance Your Career

    • 1 Edición
    • Lesia L. Crumpton-Young
    • Inglés
    Key Productivity and Performance Strategies to Advance Your STEM Career shares valuable knowledge and insights on best practices used by high performing individuals in the STEM fields to enhance their professional endeavors. The strategies contained in this book are based on Lesia L. Crumpton-Young's experience and expertise as a STEM professional and a certified Life and Career Coach. The book includes real-life examples from STEM professionals of career hurdles and efficient solutions to reaching your career goals. It covers effective goal setting, decision-making, and how best to overcome doubt and criticism, as well as practical advice on critical path analysis. Finally, the book includes a five-year career planning tool, along with additional problem statements and exercises, making it a valuable resource those involved in the STEM fields.

  • Anatomy and Histology of the Laboratory Rat in Toxicology and Biomedical Research

    • 1 Edición
    • Robert L. Maynard + 1 más
    • Inglés
    Anatomy and Histology of the Laboratory Rat in Toxicology and Biomedical Research presents the detailed systematic anatomy of the rat, with a focus on toxicological needs. Most large works dealing with the laboratory rat provide a chapter on anatomy, but fall far short of the detailed account in this book which also focuses on the needs of toxicologists and others who use the rat as a laboratory animal. The book includes detailed guides on dissection methods and the location of specific tissues in specific organ systems. Crucially, the book includes classic illustrations from Miss H. G. Q. Rowett, along with new color photo-micrographs. Written by two of the top authors in their fields, this book can be used as a reference guide and teaching aid for students and researchers in toxicology. In addition, veterinary/medical students, researchers who utilize animals in biomedical research, and researchers in zoology, comparative anatomy, physiology and pharmacology will find this book to be a great resource.

  • Engineering Tools in the Beverage Industry

    Volume 3: The Science of Beverages
    • 1 Edición
    • Alexandru Grumezescu + 1 más
    • Inglés
    Engineering Tools in the Beverage Industry, Volume Three in The Science of Beverages series, is an invaluable resource for anyone in the beverages field who is involved with quality assurance, lab analysis, and the safety of beverage products. The book offers updates on the latest techniques and applications, including extraction, biochemical isotope analysis, metabolomics, microfiltration, and encapsulation. Users will find this book to be an excellent resource for industrial research in an ever-changing field.

  • Mosaic of Autoimmunity

    The Novel Factors of Autoimmune Diseases
    • 1 Edición
    • Carlo Perricone + 1 más
    • Inglés
    The Mosaic of Autoimmunity: The Novel Factors of Autoimmune Diseases describes the multifactorial origin and diversity of expression of autoimmune diseases in humans. The term implies that different combinations of factors in autoimmunity produce varying and unique clinical pictures in a wide spectrum of autoimmune diseases. Most of the factors involved in autoimmunity can be categorized into four groups: genetic, immune defects, hormonal and environmental factors. In this book, the environmental factors are reviewed, including infectious agents, vaccines as triggers of autoimmunity, smoking and its relationship with rheumatoid arthritis, systemic lupus erythematosus, thyroid disease, multiple sclerosis and inflammatory bowel diseases. An entirely new syndrome, the autoimmune/inflammat... syndrome induced by adjuvants (ASIA), is also included, along with other diseases that are now recognized as having an autoimmune etiopathogenesis.

  • Artificial Neural Networks for Engineering Applications

    • 1 Edición
    • Alma Y Alanis + 2 más
    • Inglés
    Artificial Neural Networks for Engineering Applications presents current trends for the solution of complex engineering problems that cannot be solved through conventional methods. The proposed methodologies can be applied to modeling, pattern recognition, classification, forecasting, estimation, and more. Readers will find different methodologies to solve various problems, including complex nonlinear systems, cellular computational networks, waste water treatment, attack detection on cyber-physical systems, control of UAVs, biomechanical and biomedical systems, time series forecasting, biofuels, and more. Besides the real-time implementations, the book contains all the theory required to use the proposed methodologies for different applications.

  • Global Perspectives on Childhood Obesity

    Current Status, Consequences and Prevention
    • 2 Edición
    • Debasis Bagchi
    • Inglés
    Global Perspectives on Childhood Obesity: Current Status, Consequences and Prevention, Second Edition examines the current childhood obesity epidemic, outlines the consequences of this crisis, and develops strategies to forestall and prevent it. This book provides a thorough investigation of the causes of childhood obesity and, more importantly, offers specific prevention strategies that can be used by medical and mental health professionals, policymakers, community organizers, and individuals. New chapters on BMI and cardiovascular disease, exercise, neurotransmitters, neurocognition, nutrigenomics and combined prevention strategies are included, making this a solid introduction on the childhood obesity crisis. Researchers, practitioners, and advanced students in public health, health policy, and health economics, as well those working in medicine, pharmacy, nutrition, school health, physiology, and neuroscience related to obesity will find this to be a comprehensive resource.

  • Science Teaching Essentials

    Short Guides to Good Practice
    • 1 Edición
    • Cynthia J. Brame
    • Inglés
    Science Teaching Essentials: Short Guides to Good Practice serves as a reference manual for science faculty as they set up a new course, consider how to teach the course, figure out how to assess their students fairly and efficiently, and review and revise course materials. This book consists of a series of short chapters that instructors can use as resources to address common teaching problems and adopt evidence-based pedagogies. By providing individual chapters that can be used independently as needed, this book provides faculty with a just-in-time teaching resource they can use to draft a new syllabus. This is a must-have resource for science, health science and engineering faculty, as well as graduate students and post-docs preparing for future faculty careers.

  • Computational Epigenetics and Diseases

    • 1 Edición
    • Volumen 9
    • Inglés
    Computational Epigenetics and Diseases, written by leading scientists in this evolving field, provides a comprehensive and cutting-edge knowledge of computational epigenetics in human diseases. In particular, the major computational tools, databases, and strategies for computational epigenetics analysis, for example, DNA methylation, histone modifications, microRNA, noncoding RNA, and ceRNA, are summarized, in the context of human diseases. This book discusses bioinformatics methods for epigenetic analysis specifically applied to human conditions such as aging, atherosclerosis, diabetes mellitus, schizophrenia, bipolar disorder, Alzheimer disease, Parkinson disease, liver and autoimmune disorders, and reproductive and respiratory diseases. Additionally, different organ cancers, such as breast, lung, and colon, are discussed. This book is a valuable source for graduate students and researchers in genetics and bioinformatics, and several biomedical field members interested in applying computational epigenetics in their research.

  • Meditation

    • 1 Edición
    • Volumen 244
    • Inglés
    Meditation, Volume 244, the latest release in the Progress in Brain Research series, highlights new advances in the field with this new volume presenting interesting chapters on The effect of meditation on attentional processes, State-trait influences of Vipassana meditation practice on P3 EEG dynamics, What could teachers learn from the neuroscience of self-experience?, Training Attention for Conscious Non-REM Sleep: The Yogic Technique of Yoga Nidrā and Its Implications for Neuroscience Research, CNV and P3 modulations following sensorimotor training, Analytical meditation: a characterization of a reasoning-based meditation training, Buddhist meditation and the regulation of brain networks, Mindfulness-based Emotional Balance Training in Military Spouse, and more.

  • Bioactive Food as Dietary Interventions for Diabetes

    • 2 Edición
    • Ronald Ross Watson + 1 más
    • Inglés
    Bioactive Food as Dietary Interventions for Diabetes, Second Edition is a valuable scientific resource that explores the latest advances in bioactive food research and the potential benefits of bioactive food choice on diabetic conditions. Written by experts from around the world, it presents important information that can help improve the health of those at risk for diabetes and diabetes related conditions using food selection as its foundation. This important resource for those involved in the dietary and nutritional care of diabetic patients is also ideal for researchers seeking information on alternative bioactive food-based solutions.

  • International Review of Cell and Molecular Biology

    • 1 Edición
    • Volumen 343
    • Inglés
    International Review of Cell and Molecular Biology, Volume 343 reviews and details current advances in cell and molecular biology. The IRCMB series has a worldwide readership, maintaining a high standard by publishing invited articles on important and timely topics that are authored by prominent cell and molecular biologists. Sections in this new release include The Molecular and Cellular Regulation of Brassicaceae Self-Incompatibility and Self-Pollen Rejection, Regulation of Plant Immunity by the Proteasome, the Role of the Ubiquitin Proteasome System in Plant Response to Abiotic Stress, Glycosylation in Anticancer Immunity, Emerging Themes in PDZ Domain Signaling: Structure, Function and Inhibition, and more.

  • Animals in Disasters

    • 1 Edición
    • Dick Green
    • Inglés
    **Selected for 2026 Doody's Core Titles in Veterinary Medicine**Animals in Disasters is a comprehensive book on animal rescue written by Dr. Dick Green who shares his experiences, best practices and lessons learned from well over 125 domestic and international disasters. It provides a step-by-step process for communities and states to more effectively address animal issues and enhance their animal response capabilities. Sections include an overview of the history of animal rescue, where we are today, and the steps needed to better prepare for tomorrow. This how-to book for emergency managers who want to develop programs, craft policy, and build response capability/capacity is an ideal companion to their work.

  • G Protein Signaling Pathways in Health and Disease

    • 1 Edición
    • Volumen 161
    • Inglés
    G Protein Signaling Pathways in Health and Disease, Volume 161 in the Progress in Molecular Biology and Translational Science series, provides informative and exciting monographs on a wide variety of research topics related to G Protein Signaling Pathways in Health and Disease. The series gives in-depth knowledge on the important molecular biological aspects of organismal physiology and function, along with insights on how this knowledge can be applied to understand and ameliorate human disease. This updated release covers Diseases associated with mutations in CNGA3, Mutations in arrestins, Diseases caused by mutations in GPR101, Diseases caused by mutations in lutropin receptor, and much more.

  • Advances in Agronomy

    • 1 Edición
    • Volumen 154
    • Donald L. Sparks
    • Inglés
    Advances in Agronomy, Volume 154 continues the legacy of this leading series and first-rate source for the latest research in agronomy. Each volume contains an eclectic group of reviews by leading scientists throughout the world. As always, the subjects covered are rich, varied and exemplary of the abundant subject matter addressed by this long-running serial. Chapters in this updated volume include Experiments, Uptake Mechanisms and Functioning of Si foliar fertilization – A Review Focusing on Maize, Rice and Wheat, Pre-drought Priming: A Key Drought Tolerance Engine in Support of Grain Development in Wheat, Bio-Waste Management in Sub-Tropical Soils of India, and more.

  • Bioactive Food as Dietary Interventions for Arthritis and Related Inflammatory Diseases

    • 2 Edición
    • Ronald Ross Watson + 1 más
    • Inglés
    Bioactive Food as Dietary Interventions for Arthritis and Inflammatory Diseases, Second Edition is a valuable scientific resource that focuses on the latest advances in bioactive food research and the potential benefit of bioactive food choice on arthritis. Written by experts from around the world, the book presents important information that can help improve the health of those at risk for arthritis and related conditions using food selection as its foundation.

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