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Elsevier

Libros en Ciencias de la Vida

  • Nanotechnology-Based Targeted Drug Delivery Systems for Lung Cancer

    • 1 Edición
    • Prashant Kesharwani
    • Inglés
    Nanotechnology-based Targeted Drug Delivery Systems for Lung Cancer is an indispensable resource that will help pharmaceutical scientists and clinical researchers design and develop novel drug delivery systems and devices for the treatment of lung cancer. As recent breakthroughs in nanomedicine are now making it possible to deliver drugs, genes and therapeutic agents to localized areas of disease to maximize clinical benefit, while also limiting unwanted side effects, this book explores promising approaches for the diagnosis and treatment of lung cancer using cutting-edge nanomedical technologies. Topics discussed include polymeric nanoparticles, solid lipid nanoparticles, liposomes, dendrimers, micelles and nanoemulsions.

  • Cancer Stem Cells

    • 1 Edición
    • Volumen 141
    • Inglés
    Cancer Stem Cells, Volume 141 in the Advances in Cancer Research series, presents the latest release in this ongoing, well-regarded serial that provides invaluable information on the exciting and fast-moving field of cancer research. Topics covered in this new release include SIX-EYA-DACH network control of cancer stem cell properties, Dormancy and the cancer cell niche, Clonal hematopoiesis: A hematopoietic stem cell disorder of aging, Stringent assays to study human breast cancer stem cells, Regulation of breast cancer stem cell specification and maintenance by hypoxia-inducible factors, Cancer stem cells in breast and prostate: fact or fiction, and much more.

  • Basic Immunology

    Functions and Disorders of the Immune System
    • 6 Edición
    • Abul K. Abbas + 2 más
    • Inglés
    Meticulously reviewed and updated for today’s medical students, Basic Immunology, 6th Edition, is a concise text expertly written by the same distinguished author team as the best-selling, comprehensive text, Cellular and Molecular Immunology. This focused, easy-to-understand volume uses full-color illustrations and clinical images, useful tables, and practical features such as Summary Point boxes, end-of-chapter review questions, glossary terms, and clinical cases—all designed to help students master this complex topic in the most efficient, effective manner possible.

  • CRISPR-Cas Enzymes

    • 1 Edición
    • Volumen 616
    • Inglés
    CRISPR-Cas Enzymes, Volume 616, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Topics covered in this release include CRISPR bioinformatics, A method for one-step assembly of Class 2 CRISPR arrays, Biochemical reconstitution and structural analysis of ribonucleoprotein complexes in Type I-E CRISPR-Cas systems, Mechanistic dissection of the CRISPR interference pathway in Type I-E CRISPR-Cas system, Site-specific fluorescent labeling of individual proteins within CRISPR complexes, Fluorescence-based methods for measuring target interference by CRISPR-Cas systems, Native State Structural Characterization of CRISRP Associated Complexes using Mass Spectrometry, and more.

  • Aldosterone

    • 1 Edición
    • Volumen 109
    • Inglés
    Aldosterone, Volume 109, the latest release in the Vitamins and Hormones series first published in 1943, covers the field of hormone action, vitamin action, X-ray crystal structure, physiology and enzyme mechanisms, with this release focusing on topics relating to Aldosterone Research, Aldosterone and Micrornas, the Evolution of the Mineralocorticoid Receptor, Aldosterone and Kidney Micrornas, Adipocyte Mineralocorticoid Receptor, Regulation of Aldosterone Secretion, Leptin and Aldosterone, Cell- and Ligand-Specific Interactions in Mineralocorticoid Receptor Signaling, Primary Aldosteronism, Present and Future, Aldosterone-Producin... Adenomas, Overexpression of the Mineralocorticoid Receptor, Aldosterone and Myocardial Pathology, and much more.

  • The Transformative Power of Mobile Medicine

    Leveraging Innovation, Seizing Opportunities and Overcoming Obstacles of mHealth
    • 1 Edición
    • Paul Cerrato + 1 más
    • Inglés
    The Transformative Power of Mobile Medicine: Leveraging Innovation, Seizing Opportunities, and Overcoming Obstacles of mHealth addresses the rapid advances taking place in mHealth and their impact on clinicians and patients. It provides guidance on reliable mobile health apps that are based on sound scientific evidence, while also offering advice on how to stay clear of junk science. The book explores the latest developments, including the value of blockchain, the emerging growth of remote sensors in chronic patient care, the potential use of Amazon Alexa and Google Assistant as patient bedside assistants, the use of Amazon’s IoT button, and much more. This book enables physicians and nurses to gain a deep understanding of the strengths and weaknesses of mobile health and helps them choose evidence-based mobile medicine tools to improve patient care.

  • Advances in Food and Nutrition Research

    • 1 Edición
    • Volumen 87
    • Fidel Toldra
    • Inglés
    Advances in Food and Nutrition Research, Volume 87 provides updated information on nutrients in foods and how to avoid deficiency, especially the essential nutrients that should be present in the diet to reduce disease risk and optimize health. The book provides the latest advances on the identification and characterization of emerging bioactive compounds with putative health benefits. Chapters in this new release include discussions of the function and application of bioactive peptides from corn gluten meal, Dietary fatty acids and metabolic syndrome, the Microbial ecology of plant-based fermented foods and current knowledge on their impact on human health, and much more.

  • Role of Inflammation in Environmental Neurotoxicity

    • 1 Edición
    • Volumen 3
    • Inglés
    Role of Inflammation in Environmental Neurotoxicity, Volume Three, in this comprehensive serial, addresses contemporary advances in neurotoxicology by providing authoritative review articles on key issues in the field. Edited by leading subject experts, topics of note in this new release include Neuroinflammation (Introduction), Organophosphates, Lead, Manganese, Drugs of abuse, Peripheral vs central inflammation, Air pollution, Developmental neurotoxicity, Ethanol, and the Blood brain barrier, amongst other topics.

  • The Changing Era of Diseases

    • 1 Edición
    • Yun-Chul Hong
    • Inglés
    The Changing Era of Diseases not only explores how to end humanity’s suffering from illness, but also attempts to explain the challenging problems that may arise from the control of future disease. It provides a novel perspective on how to understand the changing patterns of disease, disease development, and defense from an evolutionary point-of-view in an effort to ally the life sciences and historical approaches. Topics cover the origin of disease, its pandemic infectious manifestation, chronic and late chronic diseases, strategies of the human body to fight diseases, methods of ending diseases, and future medical systems are featured. The book is a valuable source for researchers interested in systematic approaches to disease and students who are interested in understanding the evolution of diseases and how we have succeeded in fighting them.

  • Encyclopedia of Animal Behavior

    • 2 Edición
    • Jae C. Choe
    • Inglés
    Encyclopedia of Animal Behavior, Second Edition, Four Volume Set the latest update since the 2010 release, builds upon the solid foundation established in the first edition. Updated sections include Host-parasite interactions, Vertebrate social behavior, and the introduction of ‘overview essays’ that boost the book's comprehensive detail. The structure for the work is modified to accommodate a better grouping of subjects. Some chapters have been reshuffled, with section headings combined or modified.

  • Cognitive Rehabilitation of Memory

    A Clinical-Neuropsychological Introduction
    • 1 Edición
    • Helmut Hildebrandt
    • Inglés
    Cognitive Rehabilitation of Memory: A Clinical-Neuropsycho... Introduction comprehensively reviews evidence-based research for each clinical tool, defining guidelines on how to assess patients and set treatment goals and best practices for creating individualized rehabilitation programs. The book also provides essential background knowledge on the nature and causes of memory impairment. Dr. Helmut Hildebrandt describes a wide range of interventions, including memory aids, learning strategies and non-cognitive treatment options

  • Alzheimer’s Disease Theranostics

    • 1 Edición
    • Magisetty Obulesu
    • Inglés
    Alzheimer’s Disease Theranostics discusses the latest information on recent theranostic avenues for both the diagnosis and treatment of Alzheimer’s patients. It presents the pros and cons of the probable mechanistic role of nanoparticles in crossing the blood-brain barrier and improving disease symptoms. Finally, it highlights the merits of existing maneuvers and suggests perspectives to aid in future developments. Despite the difficulty of drug delivery to the brain, there are some nanoparticulate platforms demonstrating promise in treating neurodegenerative disorders such as Alzheimer’s disease. Manifold theranostic maneuvers include antioxidants, natural bioactive compounds, gene therapy, and nanotechnological approaches, all of which are discussed in this important work.

  • AGO-Driven Non-Coding RNAs

    Codes to Decode the Therapeutics of Diseases
    • 1 Edición
    • Bibekanand Mallick
    • Inglés
    The ‘RNA world’ hypothesis that proposed RNA molecules as the first form of genetic material was put forwarded in the late 1980s but got impetus only recently when high-throughput sequencing technologies began unearthing new types of non-coding RNA (ncRNA) transcripts in higher eukaryotes. Till then, research on ncRNAs were primarily confined to transfer RNAs and, ribosomal RNAs, which act as the messengers of the protein synthesis and allow translation of genetic information encoded by DNA into proteins. In recent years, the integration of high-throughput genomic technologies with molecular biology and omics sciences have revolutionized the fields of ncRNA research by identifying the hidden treasures of several new types of ncRNAs encoded in the genomes of several organisms and decrypting their versatile roles in gene expression and epigenetics. Among these, two small endogenous ncRNAs, namely microRNAs (miRNAs) and piwi-interacting RNAs (piRNAs) that drive argonaute (AGO) family of proteins namely Ago and Piwi respectively and silence the expression of genes have geared up molecular and disease biology research in recent years. Both miRNAs and piRNAs are expressed in higher eukaryotes, including human and act as cellular rheostats by regulating the expression of significant fraction of genes encoded in the genomes. The aberrant expressions of these small ncRNAs within the cells cause various abnormalities and diseases including cancer. Manipulating their aberrant expression or function can serve as potential novel diagnostic/prognosti... biomarkers and bring in new therapeutic strategies for multiple human diseases. This can be further translated from bench-side to clinic for improving human health. This book captures the essence of the pioneering work of some of the world’s leading researchers showcasing the scientific excitements surrounding the evolving regulatory roles of miRNAs and piRNAs highlighting their potential towards the diagnosis and therapeutics of various diseases. The book is geared towards scientists, students, and will particularly appeal to active investigators in RNA biology, molecular biology, cancer research as well as clinicians and will provide them a comprehensive view of recent discoveries and research progresses to utilize miRNAs, piRNAs and their interacting proteins, Ago and Piwi for diagnosis, prognosis and therapeutics of diseases.

  • Imaging in Movement Disorders: Imaging in Movement Disorder Dementias and Rapid Eye Movement Sleep Behavior Disorder

    • 1 Edición
    • Volumen 144
    • Inglés
    Imaging in Movement Disorders: Imaging in Movement Disorder Dementias and Rapid Eye Movement Sleep Behavior Disorder, Volume 144 provides an up-to-date textbook on the use of imaging modalities across the spectrum of movement disorders and dementias. The book brings together lessons learned from neuroimaging tools in the content of movement disorders, including chapters on Molecular Imaging of Dementia with Lewy Bodies, Structural and Functional Magnetic Resonance Imaging of Dementia with Lewy Bodies, Network Imaging in Parkinsonian and Other Movement Disorders: Network Dysfunction and Clinical Correlates, Neuroimaging of Rapid Eye Movement Sleep Behavior Disorder, Hybrid PET-MRI Applications in Movement Disorders, and more.

  • The Impact of Nutrition and Statins on Cardiovascular Diseases

    • 1 Edición
    • Ioannis Zabetakis + 2 más
    • Inglés
    The Impact of Nutrition and Statins on Cardiovascular Diseases presents a summary of the background information and published research on the role of food in inhibiting the development of cardiovascular diseases. Written from a food science, food chemistry, and food biochemistry perspective, the book provides insights on the origin of cardiovascular diseases, an analysis of statin therapy, their side effects, and the role of dietary intervention as an alternative solution to preventing cardiovascular diseases. It focuses on the efficacy of nutrition and statins to address inflammation and inhibit the onset of disease, while also providing nutrition information and suggested dietary interventions.

  • Biotin and Other Interferences in Immunoassays

    A Concise Guide
    • 1 Edición
    • Amitava Dasgupta
    • Inglés
    Biotin and Other Interferences in Immunoassays: A Concise Guide is aimed at clinical laboratory scientists, medical technologists and pathologists who are often the first individuals contacted by a clinician when a laboratory test result does not correlate with clinical presentation. Research scientists working in diagnostics companies will also find this information essential. Sources of errors in non-immunoassay based methods used in clinical chemistry and toxicology laboratory are also discussed so readers can get all important information from one concise guide. This succinct, user-friendly reference provides the necessary information to address high levels of biotin in clinical laboratory results.

  • Molecular Physiology and Biotechnology of Trees

    • 1 Edición
    • Volumen 89
    • Inglés
    Molecular Physiology and Biotechnology of Trees, Volume 89 in the Advances in Botanical Research series, highlights new advances in the field, with this new volume presenting interesting chapters on such topics as the Activity of the shoot apical and cambial meristems: Coordination and responses to environmental signals, Conifer functional genomics, Nitrogen storage and cycling, Tree defense against pests and pathogens, The ectomycorrhizal contribution to tree nutrition, Phytoremediation with trees, Transcriptional regulation of wood formation, Transgenic poplars, the Genomics of forest trees, and much more.

  • Rice Bran and Rice Bran Oil

    Chemistry, Processing and Utilization
    • 1 Edición
    • Ling-Zhi Cheong + 1 más
    • Inglés
    Rice Bran and Rice Bran Oil (RBO) provides much-needed best practices on the science and technology of RBO, including the chemistry, dectection methods, nutrition (including the effect of processing technologies on micronutrients) and applications. RBO contains many nutritional components, including up to 2% oryzanol, tocotrienol, and phytosterols. In addition, the fatty acid composition is well balanced with mainly oleic acid and very little linolenic acid, which allows for versatile uses in frying, cooking, and in formulating oil blends for food uses, especially as a trans-free alternative. Many food industrial sectors are seeking possibilities to use RBO in their products from not only Asia and South America, but also Europe and North America. However, there are many processing, analytical, and nutritional considerations that must be documented in one resource. This volume is perfect for those interested in understanding the many emerging potential uses for this alternative oil. Written by a team of experts from academia and industry, this book is the first of its kind. In addition, it provides an overview of related rice bran products and their development, including: • Rice bran protein• Rice dietary fiber• Dietary rice bran/meal• Rice husk/ash applications• Paddy straw applications• Valued added products, including rice bran wax

  • Stress: Physiology, Biochemistry, and Pathology

    Handbook of Stress Series, Volume 3
    • 1 Edición
    • George Fink
    • Inglés
    Approx.406 pages

  • Neuroblastoma

    Molecular Mechanisms and Therapeutic Interventions
    • 1 Edición
    • Swapan K. Ray
    • Inglés
    Neuroblastoma: Molecular Mechanisms and Therapeutic Interventions comprehensively reviews current concepts in molecular and histopathological mechanisms that influence the growth of human malignant neuroblastoma, along with exciting therapeutic interventions. This book features a broad collection of contributions from leading investigators in histopathology, molecular mechanisms, genetics, epigenetics, microRNAs, proteomics, and metabolism in controlling growth and death in neuroblastoma. Recent developments in therapeutic interventions for neuroblastoma are also covered extensively, including chapters on surgery, chemotherapy, targeted therapy and immunotherapy. This book is ideal for advanced undergraduate students, graduate students, medical students, postdoctoral fellows, and investigators with an interest in current molecular concepts and therapeutic interventions.

  • Biological NMR Part B

    • 1 Edición
    • Volumen 615
    • Inglés
    Biological NMR, Part B, the latest release in the Methods of Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics, including Protein methyl labeling, Membrane protein expression – yeast, Protein aromatic labeling, His-tag/Metal contamination, Bicelles, nanodiscs & micelles MP host, PTM – phosphorylation, PTM – lipidation, Screening platform for receptor-ligand discovery, Solution Spectroscopy, Large protein strategies, NUS data collection/analysis, F19 incl. hydration, ODNP - hydration, Reverse micelle - Hydration, Solid State Spectroscopy, SS NMR membrane proteins, SS NMR soluble/aggregate proteins, SS DNP - general, SS NMR nucleic acids, and much more.

  • Dietary Interventions in Liver Disease

    Foods, Nutrients, and Dietary Supplements
    • 1 Edición
    • Ronald Ross Watson + 1 más
    • Inglés
    Dietary Interventions in Liver Disease: Foods, Nutrients, and Dietary Supplements provides valuable insights into the agents that affect metabolism and other health-related conditions in the liver. It provides nutritional treatment options for those suffering from liver disease. Information is presented on a variety of foods, including herbs, fruits, soy and olive oil, thus illustrating that variations in intake can change antioxidant and disease preventing non-nutrients that affect liver health and/or disease promotion. This book is a valuable resource for biomedical researchers who focus on identifying the causes of liver diseases and food scientists targeting health-related product development.

  • Critical Issues in Alcohol and Drugs of Abuse Testing

    • 2 Edición
    • Amitava Dasgupta
    • Inglés
    Critical Issues in Alcohol and Drugs of Abuse Testing, Second Edition, addresses the general principles and technological advances for measuring drugs and alcohol, along with the pitfalls of drugs of abuse testing. Many designer drugs, for example, are not routinely tested in drugs of abuse panels and may go undetected in a drug test. This updated edition is a must-have for clinical pathologists, toxicologists, clinicians, and medical review officers and regulators, bridging the gap between technical and clinical information. Topics of note include the monitoring of pain management drugs, bath salts, spices (synthetic marijuana), designer drugs and date rape drugs, and more.

  • Dietary Interventions in Gastrointestinal Diseases

    Foods, Nutrients, and Dietary Supplements
    • 1 Edición
    • Ronald Ross Watson + 1 más
    • Inglés
    Dietary Interventions in Gastrointestinal Diseases: Foods, Nutrients and Dietary Supplements provides valuable insights into the agents that affect metabolism and other health-related conditions in the gastrointestinal system. It provides nutritional treatment options for those suffering from gastrointestinal diseases including Crohn’s Disease, Inflammatory Bowel Disease, Ulcerative Colitis and Allergies, among others. Information is presented on a variety of foods, including herbs, fruits, soy and olive oil, thus showing that changes in intake can change antioxidant and disease preventing non-nutrients and affect gastrointestinal health and/or disease promotion. This book serves as a valuable resource for biomedical researchers who focus on identifying the causes of gastrointestinal diseases and food scientists targeting health-related product development.

  • Nontuberculous Mycobacteria (NTM)

    Microbiological, Clinical and Geographical Distribution
    • 1 Edición
    • Ali Akbar Velayati + 1 más
    • Inglés
    Nontuberculous Mycobacteria (NTM): Microbiological, Clinical and Geographical Distribution is a complete reference that stimulates a greater understanding of NTM infections. Sections cover microbiologic and molecular diagnostic tools, drug susceptibility tests, human genetic susceptibility, prevalence and incidence studies, clinical and radiological presentations, and clinical trials for antibiotic therapy. With the incidence rate of NTM infections increasing globally during the last decade, significant mortality and morbidity must be addressed. This important reference will provide research scientists, clinical microbiologists, hospital diagnostic technicians, and post graduate medical and science students with information on the epidemiology, prevalence, microbiology and clinical aspects of NTM.

  • Biology of T Cells - Part B

    • 1 Edición
    • Volumen 342
    • Inglés
    Biology of T Cells - Part B, Volume 342, the latest release in the International Review of Cell and Molecular Biology series, offers an overview of the major molecular and cellular aspects of T-cell biology and their links to human pathophysiology. Chapters in this release include Metabolism of T lymphocytes in health and disease, T lymphocytes and autoimmunity, Cancer immunosurveillance by T cells, T lymphocytes as targets in viral disorders, Molecular mechanisms underlying pharmacological immunosuppression, T lymphocyte-based immunotherapeutics, In silico methods to analyze T cell biology, and Engineering Platforms for T Cell Modulation.

  • Advances in Virus Research

    • 1 Edición
    • Volumen 103
    • Thomas Mettenleiter + 2 más
    • Inglés
    Advances in Virus Research, Volume 103, the latest in the Advances in Virus Research series, contains new, informative updates on the topic. First published in 1953, this series covers a diverse range of in-depth reviews, providing a valuable overview of the current field of virology. Updates to this release include a Review on phage genes that affect bacterial phenotypes, Phage lysis: new perspectives on the bacterial cell envelope, CRISPRs as the adaptive immune system of archaea and bacteria, CRESS viruses, Tupanviruses, and Giant virus evolution, amongst other topics.

  • Molecular Chaperones in Human Disorders

    • 1 Edición
    • Volumen 114
    • Inglés
    Molecular Chaperones in Human Disorders, Volume 114 in the Advances in Protein Chemistry and Structural Biology series, provides an overview of current developments in mechanisms underlying DNA repair and their involvement in maintaining chromatin repair, the balance between chromosomal repair pathways, tumorigenesis, immune signaling and infection-induced inflammation. Chapters in this new release cover Functional principles and regulation of molecular chaperones, Chaperones and retinal disorders, Protein misfolding and degradation in genetic diseases, Chaperone dysfunction in hereditary myopathic diseases, Diseases caused by functional disorder of molecular chaperones residing in the endoplasmic reticulum, and many other timely topics.

  • Innovations in Traditional Foods

    • 1 Edición
    • Charis M. Galanakis
    • Inglés
    Innovations in Traditional Foods addresses the most relevant topics of traditional foods while placing emphasis on the introduction of innovations and consumer preferences. Certain food categories, such as fruits, grains, nuts, seeds, grains and legumes, vegetables, mushrooms, roots and tubers, table olives and olive oil, wine, fermented foods and beverages, fish, meat, milk and dairy products are addressed. Intended for food scientists, technologists, engineers and chemists working in food science, product developers, SMEs, researchers, academics and professionals, this book provides a reference supporting technological advances, product development improvements and potential positioning in the traditional food market.

  • Advances in Agronomy

    • 1 Edición
    • Volumen 153
    • Donald L. Sparks
    • Inglés
    Advances in Agronomy, Volume 153, the latest release in this comprehensive series, continues its recognition as a leading, first-rate source for the latest research in agronomy. Each volume contains an eclectic group of reviews by leading scientists throughout the world. As always, the subjects covered are rich, varied, and exemplary of the abundant subject matter addressed by this long-running serial. Chapters in this updated volume include Novel Practice and Smart Technologies to Maximize the Nitrogen Fertilizer Value of Manure for Crop Production in Cold Humid Temperate Regions, Nitrogen Fertilization Management of Switchgrass, Miscanthus and Giant Reed: A Review, and much more.

  • Fundamentals of Radiation Oncology

    Physical, Biological, and Clinical Aspects
    • 3 Edición
    • Hasan Murshed
    • Inglés
    Fundamentals of Radiation Oncology: Physical, Biological, and Clinical Aspects, Third Edition continues to provide current, concise, and a readily available source of clinical information for busy practicing radiation oncologists. The book consists of 26 chapters, divided into four parts: Part I describes the basic science of radiation oncology, with discussions of radiation physics, radiation protection, and radiation biology, as well as molecular biology. Part II describes techniques and modalities of radiation oncology including brachytherapy, intensity-modulated radiation therapy (IMRT), stereotactic radiotherapy (SRS), stereotactic body radiation therapy (SBRT), and proton therapy. Significant recent advances made in the areas of immunotherapy and combined modality therapy; as such, these chapters have also been added to this new edition. Part III describes the clinical science of radiation oncology including risk factors, symptoms/signs, and investigations needed for the cancer diagnosis and up-to-date treatment recommendations in accordance with the new AJCC staging system. In addition, radiation treatment techniques, with an emphasis on IMRT, have been expanded to all the chapters. Also included in this version of the book is a chapter on benign diseases. Updated annotated bibliographies of latest landmark studies providing evidence-based rationale for the recommended treatments are presented at the end of each chapter. Part IV describes palliative radiation treatments to improve the quality of life for cancer patients and the management of side effects from radiation treatment. This book is a must-have for all radiation oncology residents, radiation oncologists and all professionals engaged in the care of cancer patients.

  • G Protein-Coupled Receptors, Part B

    • 2 Edición
    • Volumen 149
    • Inglés
    G-Protein-Coupled Receptors, Part B, 2nd Edition, Volume 149, the latest release in the Methods in Cell Biology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers Optical Approaches for Visualization of Arrestin Binding to Muscarinic Receptors, Luciferase Reporter Assay for Unlocking Ligand-mediated Signaling of GPCRs, Assays to Measure GPCR Dependent Cellular Migration, Characterization of the Frizzled GPCRs, Binding Assays for Bradykinin and Angiotensin Receptors, Detection of Misfolded Rhodopsin Aggregates in Cells, Measuring GPCR Ubiquitination and Trafficking, Culture of Primary Neurons and its Use in Studying GPCR Trafficking, and much more.

  • Equine Behavioral Medicine

    • 1 Edición
    • Bonnie V. Beaver
    • Inglés
    Equine Behavioral Medicine provides an essential resource for those who work with, study, and provide care to horses. It provides critical knowledge to help users understand the complex aspects of their behavior in order to benefit the animal, observe safe practices, and advance research in this area. The book includes current information on normal horse behavior and problem behaviors, particularly those associated with medical conditions, changes in the nervous system, and the use of drug therapy. Readers will gain a comprehensive understanding of the differences of the sensory systems and the concepts of learning that are helpful for successful treatments and safety. With the use of psychopharmacology becoming increasingly common by veterinarians, including for abnormal behaviors, is important to understand the rationale for the use of these medications. Understanding the intimate relationship between behavior, physiology, and health is key to practitioners, students, professionals, and others who work with, or care for, horses.

  • Plant Development and Evolution

    • 1 Edición
    • Volumen 131
    • Inglés
    Plant Development and Evolution, the latest release in the Current Topics in Developmental Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on the Evolution of the plant body plan, Lateral root development and its role in evolutionary adaptation, the Development of the vascular system, the Development of the shoot apical meristem and phyllotaxis, the Evolution of leaf diversity, the Evolution of regulatory networks in land plants, The role of programed cell death in plant development, the Development and evolution of inflorescence architecture, the Molecular regulation of flower development, the Pre-meiotic another development, and much more.

  • Advances in Clinical Chemistry

    • 1 Edición
    • Volumen 88
    • Gregory S. Makowski
    • Inglés
    Advances in Clinical Chemistry, Volume 88, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. The serial discusses the latest and most up-to-date technologies related to the field of clinical chemistry, and is the benchmark for novel analytical approaches in the clinical laboratory.

  • The Auditory Brain and Age-Related Hearing Impairment

    • 1 Edición
    • Jos J. Eggermont
    • Inglés
    The Auditory Brain and Age-Related Hearing Impairment provides an overview of the interaction between age-related hearing impairments and cognitive brain function. This monograph elucidates the techniques used in the connectome and other brain-network studies based on electrophysiological methods. Discussions of the manifestations of age-related hearing impairment, the causes of degradation of sound processing, compensatory changes in the human brain, and rehabilitation and intervention are included. There is currently a surge in content on aging and hearing loss, the benefits of hearing aids and implants, and the correlation between hearing loss, cognitive decline and early onset of dementia. Given the changing demographics, treatment of age-related hearing impairment need not just be bottom-up (i.e., by amplification and/or cochlear implantation), but also top-down by addressing the impact of the changing brain on communication. The role of age-related capacity for audio-visual integration and its role in assisting treatment have only recently been investigated, thus this area needs more attention.

  • Biological NMR Part A

    • 1 Edición
    • Volumen 614
    • A.Joshua Wand
    • Inglés
    Biological NMR, Part A, the latest release in the Methods of Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Protein methyl labeling, Membrane protein expression – yeast, Protein aromatic labeling, His-tag/Metal contamination, Bicelles, nanodiscs and micelles MP host, PTM – phosphorylation, PTM – lipidation, Screening platform for receptor-ligand discovery Solution Spectroscopy, Large protein strategies, NUS data collection/analysis, F19 incl. hydration, ODNP - hydration, Reverse micelle - Hydration Solid State Spectroscopy, SS NMR membrane proteins, SS NMR soluble/aggregate proteins, SS DNP - general, SS NMR nucleic acids, Structure determination and computer analysis, and much more.

  • Microbiome and Metabolome in Diagnosis, Therapy, and other Strategic Applications

    • 1 Edición
    • Joel Faintuch + 1 más
    • Inglés
    Microbiome and Metabolome in Diagnosis, Therapy, and Other Strategic Applications is the first book to simultaneously cover the microbiome and the metabolome in relevant clinical conditions. In a pioneering fashion, it addresses not only the classic intestinal environment, but also the oral, gastric, lung, skin and vaginal microbiome that is in line with the latest investigations. Nonbacterial microbiomes, such as fungi and viruses are not overlooked, and the plasma microbiome is also discussed. As plasma, brain, placenta, tumor cells, and other sterile fluids and tissues, are increasingly recognized to potentially host a microbiome, albeit a limited one, this is a timely resource. The book's editors were fortunate to have the input of renowned collaborators from nearly all continents. This is truly an international effort that brings the latest in the field to students and professionals alike.

  • The Orexin/Hypocretin System

    Functional Roles and Therapeutic Potential
    • 1 Edición
    • Jim R. Fadel + 1 más
    • Inglés
    The Orexins/Hypocretins System: Functional Roles and Therapeutic Potential summarizes research on both the physiological functioning of orexins, their impact on homeostatic processes, and related disorders. The book encompasses the effects on appetite, sleep, substance abuse, cognition, and anxiety. Additionally, it examines new therapeutic approaches utilizing orexins, including utilization of orexin receptors for drug development. It is essential reading for neuroscience researchers interested in brain-behavior relationships, as well as psychiatrists, endocrinologists and pharmacologists.

  • Neurobiology of Depression

    Road to Novel Therapeutics
    • 1 Edición
    • Joao L. de Quevedo + 2 más
    • Inglés
    Neurobiology of Depression: Road to Novel Therapeutics synthesizes the basic neurobiology of major depressive disorder with discussions on the most recent advances in research, including the interacting pathways implicated in the pathophysiology of MDD, omics technologies, genetic approaches, and the development of novel optogenetic approaches that are changing research perspectives and revolutionizing research into depression. These basic foundational understandings on the neurobiology underlying the disorder, along with a comprehensive summary of the most recent advances in research are combined in this book to aid advanced students and researchers in their understanding of MDD. Depression is one of the most common mental-health disorders caused by a variety of genetic, biological, environmental and psychological factors. Major depressive disorder (MDD) is typically treated with first-line antidepressant agents that primarily target monoamine neurotransmission. However, only approximately one-third of patients with MDD achieve remission following a trial with such an antidepressant. Furthermore, MDD is a heterogeneous phenotype, and new frameworks, such as the NIMH Research Domain Criteria (RDoC) may provide a more accurate, biologically based comprehension of the symptomatic heterogeneity of this devastating illness.

  • Atlas of the Morphology of the Human Cerebral Cortex on the Average MNI Brain

    • 1 Edición
    • Michael Petrides
    • Inglés
    Atlas of the Morphology of the Human Cerebral Cortex on the Average MNI Brain provides a comprehensive identification of the sulci and gyri of the human brain on a series of coronal sections of the average MNI brain and identifies the likely location of the cytoarchitectonic areas of the cerebral cortex. Presentation in MNI Stereotaxic Space enables the atlas to serve as a useful working tool for structural/functiona... neuroimagers attempting to identify the sulcus or gyrus and the likely cytoarchitectonic area within which a functional activation or a structural change has occurred. A brief introductory section discusses the history and current state of studies of the sulcal and gyral morphology and cytoarchitecture of the human cerebral cortex.

  • Processing and Sustainability of Beverages

    Volume 2: The Science of Beverages
    • 1 Edición
    • Alexandru Grumezescu + 1 más
    • Inglés
    Processing and Sustainability of Beverages, Volume Two in the Science of Beverages series, is a general reference of the current and future actions for a sustainable beverage industry. This resource takes a unique approach, combining processing with sustainability. Topics of note include waste treatment and management, environmental analysis for a sustainable beverage industry, and modern technologies for beverage processing to reduce contaminants and increase the quality. This book is essential to scientists, researchers and technologists in the beverages field, covering both alcoholic and nonalcoholic beverages.

  • Production and Management of Beverages

    Volume 1. The Science of Beverages
    • 1 Edición
    • Alexandru Grumezescu + 1 más
    • Inglés
    Production and Management of Beverages, Volume One in the Science of Beverages series, introduces the broad world of beverage science, providing an overview of the emerging trends in the industry and the potential solutions to challenges such as sustainability and waste. Fundamental information on production and processing technologies, safety, quality control, and nutrition are covered for a wide range of beverage types, including both alcoholic and nonalcoholic beverages, fermented beverages, cocoa and other powder based beverages and more. This is an essential resource for food scientists, technologists, chemists, engineers, microbiologists and students entering into this field.

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    An Eyewitness Account
    • 1 Edición
    • Luke Ekundayo Edungbola
    • Inglés
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  • Imagining the Brain: Episodes in the History of Brain Research

    • 1 Edición
    • Volumen 243
    • Chiara Ambrosio + 1 más
    • Inglés
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  • Bioactive Compounds

    Health Benefits and Potential Applications
    • 1 Edición
    • Maira Rubi Segura Campos
    • Inglés
    Bioactive Compounds: Health Benefits and Potential Applications provides information about different bioactive compounds including their sources, biological effects, health benefits and, potential applications which could contribute as alternatives in the prevention or treatment of multifactorial diseases for vulnerable population groups. Going beyond the basics to include discussion of bioaccessibility and the legislative aspects of marketing of bioactive compounds as nutraceuticals or food supplements, this book presents insights from a global perspective. Written for researchers, professors and graduate students, this book is sure to be a welcomed reference for all who work in food chemistry, new product development and nutritional science.

  • Sustainable Food and Agriculture

    An Integrated Approach
    • 1 Edición
    • Clayton Campanhola + 1 más
    • Inglés
    Sustainable Food and Agriculture: An Integrated Approach is the first book to look at the imminent threats to sustainable food security through a cross-sectoral lens. As the world faces food supply challenges posed by the declining growth rate of agricultural productivity, accelerated deterioration of quantity and quality of natural resources that underpin agricultural production, climate change, and hunger, poverty and malnutrition, a multi-faced understanding is key to identifying practical solutions. This book gives stakeholders a common vision, concept and methods that are based on proven and widely agreed strategies for continuous improvement in sustainability at different scales. While information on policies and technologies that would enhance productivity and sustainability of individual agricultural sectors is available to some extent, literature is practically devoid of information and experiences for countries and communities considering a comprehensive approach (cross-sectoral policies, strategies and technologies) to SFA. This book is the first effort to fill this gap, providing information on proven options for enhancing productivity, profitability, equity and environmental sustainability of individual sectors and, in addition, how to identify opportunities and actions for exploiting cross-sectoral synergies.

  • Enzymes of Energy Technology

    • 1 Edición
    • Volumen 613
    • Fraser Armstrong
    • Inglés
    Enzymes of Energy Technology, Volume 613 in the Methods in Enzymology series, highlights new advances in the field, with this updated volume presenting interesting chapters written by an international board of authors. Chapters include Purification of fully active and crystallizable photosystem II from thermophilic cyanobacteria, Production and manipulation of [NiFeSe]-hydrogenase... for renewable hydrogen research, Hydrogen production by [FeFe]-hydrogenases, Production and properties of enzymes that activate and produce carbon monoxide, Recombinant [NiFe]-hydrogenases from E. coli, Working with nitrogenase, Oxygen--tolerant [NiFe]-hydrogenases, Cytoplasmic and Membrane Bound Hydrogenases from the hyperthermophile Pyrococcus furiosus, and more. Additional sections cover Enzymatic conversion of methane into useful chemicals, Production and investigations of trans-membrane electron transfer protein, Characterization of post-translational modifications in methyl-coenzyme M reductase in diverse methanogens by mass-spectrometry, Reductive activation of carbon dioxide by formate dehydrogenases, and Lytic polysaccharide monooxygenases in biofuel processing. 14. Production and manipulation of blue copper oxidases for technological applications Yasmina Mekmouche

  • The Technology of Wafers and Waffles II

    Recipes, Product Development and Know-How
    • 1 Edición
    • Karl F. Tiefenbacher
    • Inglés
    The Technology of Wafers and Waffles: Recipes, Product Development and Knowhow is the definitive reference book addressing new product development in wafers and waffles. As a companion manual to The Technology of Wafers and Waffles: Operational Aspects, it provides a varied selection of recipes for different types of wafers, waffles, and fillings. This book discusses flat and shaped wafers, ice cream cones, cups, wafer reels, wafer sticks, stroop waffles, and North American frozen waffles. A separate chapter focuses on recipe calculations for wafer and waffle batters, doughs, and fillings, which allows estimating output, cost, and main nutrient content. Finally, there is also an overview on the patent and food science literature on wafers and waffles in chronological order.

  • Biocontamination Control for Pharmaceuticals and Healthcare

    • 1 Edición
    • Tim Sandle
    • Inglés
    Biocontamination Control for Pharmaceuticals and Healthcare outlines a biocontamination strategy that tracks bio-burden control and reduction at each transition in classified areas of a facility. This key part of controlling risk escalation can lead to the contamination of medicinal products, hence necessary tracking precautions are essential. Regulatory authorities have challenged pharmaceutical companies, healthcare providers, and those in manufacturing practice to adopt a holistic approach to contamination control. New technologies are needed to introduce barriers between personnel and the environment, and to provide a rapid and more accurate assessment of risk. This book offers guidance on building a complete biocontamination strategy.

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