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Elsevier

Libros en Ciencias de la Vida

  • Cannabinoids and Their Receptors

    • 1 Edición
    • Volumen 593
    • Inglés
    Cannabinoids and Their Receptors, Volume 593, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. This updated volume includes comprehensive chapters on a variety of topics, including Real time cAMP signaling in response to CB1 activation, CB1 signaling in mitochondria, Lipidomics of cannabinoid systems, Studying endocannabinoid transport, Metabolic profiling of CB1 neutral antagonists, Approaches to assess biased signaling at the CB1 receptor, and the Development of CB1 allosteric modulators.

  • Nitric Oxide

    Biology and Pathobiology
    • 3 Edición
    • Louis J. Ignarro + 1 más
    • Inglés
    Nitric Oxide: Biology and Pathobiology, Third Edition, provides information on nitric oxide, a signaling molecule of key importance for the cardiovascular system that regulates blood pressure and blood flow to different organs. With recent links to the role of nitric oxide in the expression of healthy benefits of controlled diet and aerobic exercise, and the reactions of nitric oxide that can impact cell signaling, this book provides a comprehensive resource during a time when increased research attention is being paid across the fields of pharmacology, biochemistry, cell and molecular biology, chemistry, immunology, neurobiology, immunology, nutrition sciences, drug development and the clinical management of both acute and chronic diseases.

  • The Role of Chromosomes in Cancer Biology

    Recent Results in Cancer Research
    • 1 Edición
    • Peo C. Kollerr
    • V. G. Allfrey + 2 más
    • Inglés
    The Role of Chromosomes in Cancer Biology provides a description of the molecular organization and function of chromosomes and the consequences of chromosomal aberrations in human development. The book presents accounts on the structure and function of the chromosome; the cellular features of primary tumors and ascetic fluid; the cytological actions of radiation and drugs and their relevance to therapy. Developmental disorders caused by chromosomal anomalies; chromosome aneuploidy in human malignancies; and viral oncogenesis are discussed as well. The book will prove to be very insightful to those involved in cancer research, oncologists, cytologists, and molecular biologists.

  • Latent Syphilis and the Autonomic Nervous System

    • 2 Edición
    • Griffith Evans
    • Inglés
    Latent Syphilis and the Autonomic Nervous System, Second Edition describes the link between the pathogenesis of syphilis and the autonomic nervous system. This book is composed of 15 chapters, and begins with a brief introduction to the pathology of syphilis, followed by chapters on the physiologic changes in the thyroid gland, including thyroid enlargement and goiter formation, in early syphilis. The succeeding chapters are devoted to syphilis-related diseases, such as allergy, asthma, vasomotor disturbances, dysphagia, dyspepsia, cancer, and superficial ulceration of the mouth. A chapter describes some clinical features in latent syphilis. The final chapter examines the clinical manifestations of pes cavus, which is both an acquired and congenital disease. This book is of value to pathologists, endocrinologists, clinicians, and medical researchers.

  • Gluten-Free Ancient Grains

    Cereals, Pseudocereals, and Legumes: Sustainable, Nutritious, and Health-Promoting Foods for the 21st Century
    • 1 Edición
    • John Taylor + 1 más
    • Inglés
    Gluten-Free Ancient Grains: Cereals, Pseudocereals and Legumes covers grains that are not related to wheat. This includes sorghum, the major millets - pearl, foxtail, proso and finger millet, as well as teff, the major pseudocereals - quinoa, amaranth and buckwheat, and emerging legume grains - lupin, cowpea, Bambara groundnut and marama beans. These are all characterized as gluten-free grains. The book provides key information on the sustainable production of these grains. Ancient grains are characterized by their ability to produce a crop under harsh environmental conditions where the major cereals are not-sustainable or even fail. In order to meet growing food demand, and with water resources becoming scarce, this is a highly valuable quality. Chapters review the major grains, analyzing their production and manufacture processes and detailing their impact on long-term good health. Of interest to many people and organizations in the food production chain, this book will be of significant value to agricultural scientists, food company innovation and R&D managers, academic and food company nutritionists and dietitians and governmental and non-governmental health ministries and research institutes.

  • Fatty Acids

    Chemistry, Synthesis, and Applications
    • 1 Edición
    • Moghis U. Ahmad
    • Inglés
    Fatty Acids: Chemistry, Synthesis and Applications is a comprehensive source of information about a wide range of industrially important fatty acids. This practical resource provides key insights into the chemistry, synthesis, industrial applications, derivatives, and analysis of fatty acids, and the chemical modifications that transform them for use in products from biodiesel fuels to pharmaceuticals. Written by a team of industry experts, Fatty Acids includes detailed descriptions of fatty acid crystallization, enzymatic synthesis, and microbial production. This book focuses heavily on the chemistry of trans fatty acids, with extensive explanations of their synthesis and measurement. Further, the book addresses advances in the analytical methodology, including mass spectrometry, of fatty acids as well as their derivatives. This book serves as a reference manual to a new generation of lipid scientists and researchers; a useful resource for oleochemical industries; and a valuable teaching aid for undergraduate and graduate students who are interested in fields related to the chemistry of oils, fats, and food.

  • New Health Systems

    Integrated Care and Health Inequalities Reduction
    • 1 Edición
    • Mohamed Lamine Bendaou + 1 más
    • Inglés
    New health systems exist today thanks to the changing nature of diseases as a result of the integration of new technologies and new approaches in care giving and the management of healthcare systems.This book studies the health inequalities in these new health systems, structured according to the integrated health services approach. The authors investigate a wide range of debates and issues, including the consequences of a collaborative economy on healthcare and the possible “uberization” of a wide range of its services.The first part of the book offers an overview of the problem of inequalities in the field of health. The second part discusses the possibility of a sustainable and equitable architecture for health systems..

  • Advances in Agronomy

    • 1 Edición
    • Volumen 145
    • Inglés
    Advances in Agronomy, Volume 145, the latest in a series that is recognized as a leading reference and first-rate source for the latest research in agronomy presents new chapters that focus on A Chinese Model for the Planet, Allelopathic Potential of Sorghum Sorghum Bicolor (L.) Moench in Weed Control: A Comprehensive Review, Weed Dynamics and Management in Wheat, Improving Soil Health and Human Protein Nutrition by Pulses-Based Cropping Systems, and Potential Hotspot Areas of Nitrous Oxide Emissions from Grazed Pastoral Dairy Farm Systems. Each volume in this regularly updated series contains an eclectic group of reviews by leading scientists.

  • Saliva Protection and Transmissible Diseases

    • 1 Edición
    • Crispian Scully + 2 más
    • Inglés
    Saliva Protection and Transmissible Diseases provides a review of saliva protection, raising debate on micro-organisms potentially transmissible in saliva, and also considering the evidence on diseases that may be transmitted by kissing. Saliva is a complex body fluid essential to health, especially mastication, swallowing and speech, and hyposalivation can lead to dysfunction and even infection. More serious pathogens, such as herpes viruses and papillomaviruses can be conveyed by kissing, as can potentially lethal micro-organisms present in some saliva, such as meningococci, fungal organisms and Ebola viruses.

  • Soft Chemistry and Food Fermentation

    • 1 Edición
    • Volumen 3
    • Alexandru Mihai Grumezescu + 1 más
    • Inglés
    Soft Chemistry and Food Fermentation, Volume Three, the latest release in the Handbook of Food Bioengineering series is a practical resource that provides significant knowledge and new perspectives in food processing and preservation, promoting renewable resources by applying soft ecological techniques (i.e. soft chemistry). Fermentation represents a simple and very efficient way to preserve food in developing countries where other methods, depending on specialized instruments, are not available. Through processes of soft chemistry and fermentation, food ingredients can be produced with improved properties (such as pharmabiotics) able to promote health.

  • Viroids and Satellites

    • 1 Edición
    • Ahmed Hadidi + 3 más
    • Inglés
    Viroids and Satellites describes plant diseases and their causal agents while also addressing the economic impact of these diseases. The book discusses various strategies for state-of-the-art methods for the detection and control of pathogens in their infected hosts and provides pivotal information from the discovery of viroids through the analysis of their molecular and biological properties, to viroid pathogenesis, host interactions, and RNA silencing pathways. Students, researchers and regulators will find this to be a comprehensive resource on the topics presented.

  • Advances in Applied Microbiology

    • 1 Edición
    • Volumen 100
    • Inglés
    Advances in Applied Microbiology, Volume 100 continues to be one of the most widely read and authoritative review sources in microbiology, containing comprehensive reviews of the most current research in applied microbiology. This latest release includes specific chapters on a variety of topics, most notably, Current interventions for controlling pathogenic Escherichia coli, Microbial ecology and process technology of sourdough fermentation, Diversity, Application, and Synthetic Biology of Industrially Important Aspergillus Fungi, and Advances in the Microbial Ecology of Biohydrometallurgy. Users will find invaluable references and information on a variety of areas, including protozoan grazing of freshwater biofilms, metals in yeast fermentation processes, the interpretation of host-pathogen dialogue through microarrays and the role of polyamines in bacterial growth and biofilm formation. Eclectic volumes are supplemented by thematic volumes on various topics, including Archaea and sick building syndrome.

  • A Paradigm Shift to Prevent and Treat Alzheimer's Disease

    From Monotargeting Pharmaceuticals to Pleiotropic Plant Polyphenols
    • 1 Edición
    • Howard Friel + 1 más
    • Inglés
    A Paradigm Shift to Prevent and Treat Alzheimer’s Disease: From Monotargeting Pharmaceuticals to Pleiotropic Plant Polyphenols is the first book to systematically exhibit the powerful pleiotropic pharmacological effects on Alzheimer’s disease of plant-based compounds from ancient foods that humans have been consuming safely with substantial health benefits for thousands of years. These plant-based compounds include curcuminoids from turmeric, resveratrol from red wine and grape seed extract from other grape products, epigallocatechin-gal... (EGCG) from green tea, and oleocanthal and oleuropein from olive oil, in addition to a special extract, EGb 761, from the leaves of Ginkgo biloba, the oldest living species of tree on earth. This book also presents a new analytical framework that convincingly favors a multi-targeting ("pleiotropic") approach to the prevention and treatment of complex chronic diseases, in contrast to the mono-targeting of the pharmaceutical model. A Paradigm Shift to Prevent and Treat Alzheimer’s Disease is a unique and exciting resource for pharmaceutical scientists, pharmacologists, neurologists, general practitioners, research scientists in various medical and life sciences, healthcare professionals in clinical and executive positions, conventional medical schools, schools of naturopathic medicine, healthcare and medical journalists, executives in both national public healthcare systems and private insurers, and informed general readers.

  • Ebola's Curse

    2013-2016 Outbreak in West Africa
    • 1 Edición
    • Michael B.A. Oldstone + 1 más
    • Inglés
    Ebola‘s Curse: 2013-2016 Outbreak in West Africa is about hemorrhagic fever viruses, especially Ebola, its initial origin in central Africa 1976, its unprecedented appearance in West Africa in 2013. The book records in sequence and detective style how the initial outbreak of Ebola from the index case in rural Guinea traveled to Sierra Leone, the work and fate of those working in the Kenema Government Hospital (KGH) isolation ward in Sierra Leone. The book provides vignettes of the three main players involved with Ebola at KGH, Sheik Khan, Pardis Sabeti, and Robert Garry. Khan was the head of the unit, declared a national hero by his Sierra Leone government. He died fighting Ebola and was/is recognized in the USA by American societies by awards created for his historic work and death. Pardis Sabeti, a geneticist from Harvard and Broad MIT Institute, who was honored as a "Scientist of the Year" by Time Magazine and the Smithsonian Institute. Robert Garry, head of the operation to fight hemorrhagic fevers and Ebola, shuttled between Tulane University, KGH, and The White House to make aware through the press and others the dilemma and tragedy that was unfolding, and the need to obtain additional medical and health care support and supplies. Sabeti and Garry currently work with Oldstone on Ebola at KGH and thus personal communication and knowledge was/is available to the author for the book.

  • MiRNAs in Differentiation and Development

    • 1 Edición
    • Volumen 333
    • Inglés
    MiRNAs in Differentiation and Development, Volume 333, the latest in the International Review of Cell and Molecular Biology series, reviews and details current advances in cell and molecular biology. Topics in this updated volume include chapters on the Regulation of the DNA damage response by miRNAs, miRNAs and the p53 network, the Impact of miRNAs in the cellular response to hypoxia, miRNAs in oncogenesis and tumor suppression, and the Role of miRNAs in metastatic dissemination. The IRCMB series has a worldwide readership, maintaining a high standard by publishing articles on timely topics that are authored by prominent cell and molecular biologists. The articles published in IRCMB have a high impact and an average cited half-life of nine years. This great resource ranks high amongst scientific journals dealing with cell biology.

  • Piezo Channels

    • 1 Edición
    • Volumen 79
    • Inglés
    Piezo Channels, Volume 79, the latest volume in the Current Topics in Membranes series provides the necessary membrane research to assist readers in discovering the current state of a particular field and future directions. New chapters in the updated volume include A Tour de Force: The Discovery, Properties, and Function of Piezo Channels, Piezo1 Channels in Vascular Development and the Sensing of Shear Stress, the Origin of the Force: The Force-From-Lipids Principle Applied to Piezo Channels, Genetic Diseases of PIEZO1 and PIEZO2 Dysfunction, and The Structural Basis for Sensing by the Piezo1 Protein. Users of this series will find an up-to-date presentation of the current knowledge in the field of Piezo Channels.

  • Cytokine Effector Functions in Tissues

    • 1 Edición
    • Maria Foti + 1 más
    • Inglés
    Cytokine Effector Functions in Tissues discusses the cytokines networks in the context of the specific-tissue environment. It is an up-to-date collection of articles that addresses the specific issue of how the cytokines are able to condition tissue specific homeostasis. The book helps the reader understand how cytokines network inside the tissues and highlights whether tissue-protection or exacerbation will be finally controlled. It describes the cytokines detected and regulated in different tissues, such as the brain, lungs, spleen, liver, pancreas and intestine, also addressing the issue of timing in specific cell types.

  • Advances in Optical and Electron Microscopy

    • 1 Edición
    • Volumen 11
    • T Mulvey + 1 más
    • Inglés
    Advances in Optical and Electron Microscopy, Volume 11 compiles papers on the important developments in optical and electron microscopy. This book discusses the instrumentation and operation for high-resolution electron microscopy; diffraction pattern and camera length; and electron microscopy of surface structure. The history of surface imaging by conventional transmission electron microscopy; ion probe microscopy; and secondary ion mass spectrometry with high lateral resolution are also elaborated. This text likewise covers the acoustic microscopy; quantitative methods; biological applications and near-surface imaging of solids; and interior imaging. This publication is a beneficial to students and individuals researching on optical and electron microscopy.

  • Neurobiological Background of Exploration Geosciences

    New Methods for Data Analysis Based on Cognitive Criteria
    • 1 Edición
    • Paolo Dell'Aversana
    • Inglés
    Neurobiological Background of Exploration Geosciences: New Methods for Data Analysis Based on Cognitive Criteria examines the neurobiological background of earth science disciplines. It presents the fundamental features of the human brain that form the cognitive basis of exploration geophysics and investigates how their analysis can drive the development of new brain-based technologies. Crucial aspects of human cognition include the impulse to explore the environment, the ability of our brain to create mental maps and virtual images of the world, and the human ability to recognize, integrate and save patterns of information in a shared memory. Geoscience technology can be made more effective by taking the working neurobiological principles of our brains into account. This book is appropriate for multiple audiences, including neuroscientists, cognitive scientists and geoscientists, presenting both theoretical and experimental results.

  • Chronic Traumatic Encephalopathy

    Proceedings of the Boston University Alzheimer’s Disease Center Conference
    • 1 Edición
    • Andrew E. Budson + 3 más
    • Inglés
    Get a thorough, expert overview of the many key facets of chronic traumatic encephalopathy (CTE) with this concise, practical resource by Drs. Andrew E. Budson, Ann C. McKee, Robert C. Cantu, and Robert A. Stern. This easy-to-read reference is based on lectures from Boston University’s Alzheimer’s Disease Center’s November 2016 two-day conference on CTE.

  • Preharvest Modulation of Postharvest Fruit and Vegetable Quality

    • 1 Edición
    • Mohammed Wasim Siddiqui
    • Inglés
    Preharvest Modulation of Postharvest Fruit and Vegetable Quality is the first book to focus on the potential yield quality, quantity and safety benefits of intervention during growth. Of the many factors responsible for overall quality of produce, about 70 percent comes from pre-harvest conditions. Written by an international team of experts, this book presents the key opportunities and challenges of pre-harvest interventions. From selecting the most appropriate growing scenario, to treating plants during the maturation process, to evaluating for quality factors to determine appropriate interventions, this book provides an integrated look at maximizing crop yield through preventative means. In fact, with the very best of postharvest knowledge and technologies available, the best that can be achieved is a reduction in the rate at which products deteriorate as they progress through their normal developmental pattern of maturation, ripening and senescence. Therefore, it is very important to understand what pre-harvest factors influence the many important harvest quality attributes that affect the rate of postharvest deterioration and, subsequently, the consumers’ decision to purchase the product in the marketplace.

  • Nanotechnology Methods for Neurological Diseases and Brain Tumors

    Drug Delivery across the Blood–Brain Barrier
    • 1 Edición
    • Yasemin Gürsoy Özdemir + 2 más
    • Inglés
    Nanotechnology Methods for Neurological Diseases and Brain Tumors: Drug Delivery across the Blood-Brain Barrier compiles the latest (and future potential) treatment strategies for brain tumors and neurological diseases, in particular Alzheimer’s, Parkinson’s and stroke, those that bypass the blood/brain barrier. The current understanding of brain drug delivery and access is discussed in Chapter One, with the next section focusing on the implementation of the nose-to-brain intranasal route in brain-targeted drug delivery. In addition, nanotechnology-based brain drug delivery is covered in Chapter Three. This avenue offers impressive improvement in the treatment of neurological diseases and brain tumors by using bio-engineered systems that interact with biological systems at a molecular level. In Chapter Four, emphasis is placed on the need for brain-targeted experimental models that mimic disease conditions. Final chapters discuss the very latest advances in targeted treatment strategies for neurological diseases and brain tumors.

  • Gene Editing in Plants

    • 1 Edición
    • Volumen 149
    • Inglés
    Gene Editing in Plants, Volume 149 aims to provide the reader with an up-to-date survey of cutting-edge research with gene editing tools and an overview of the implications of this research on the nutritional quality of fruits, vegetables and grains. New chapters in the updated volume include topics relating to Genome Engineering and Agriculture: Opportunities and Challenges, the Use of CRISPR/Cas9 for Crop Improvement in Maize and Soybean, the Use of Zinc-Finger Nucleases for Crop Improvement, Gene Editing in Polyploid Crops: Wheat, Camelina, Canola, Potato, Cotton, Peanut, Sugar Cane, and Citrus, and Gene Editing With TALEN and CRISPR/Cas in Rice. This ongoing serial contain contributions from leading scientists and researchers in the field of gene editing in plants who describe the results of their own research in this rapidly expanding area of science.

  • Noradrenergic Signaling and Astroglia

    • 1 Edición
    • Nina Vardjan + 1 más
    • Inglés
    Noradrenergic Signaling and Astroglia integrates what is known about the active role of astroglia in the locus coeruleus-noradrener... system and outlines the most recent advances in the field. It discusses the molecular mechanisms underlying norepinephrine-induc... receptor activation in astroglia, cellular metabolism and CNS energy provision, in vitro, ex vivo, and in vivo models, gliosignalling and neuronal activity, and astroglial networks, gap junctions, and morphological plasticity. The book also addresses the role of astroglial adrenergic receptor activation in memory formation, cognition, regulation of sleep homeostasis, and lastly in neurological disorders, including trauma (cellular edema), neurodegeneration (Alzheimer’s disease), and neuroinflammation (multiple sclerosis). Noradrenergic Signaling and Astroglia is a valuable source of new knowledge for a wide audience, including graduate students, post-doctoral fellows, and researchers in neuroscience, life sciences, and the biological and biomedical sciences.

  • Sports Neurology, An Issue of Neurologic Clinics

    • 1 Edición
    • Volumen 35-3
    • Tad Seifert
    • Inglés
    This issue of Neurologic Clinics, Edited by Dr. Tad Seifert, will do a comprehensive review of Sports Neurology. Some of the topics discussed in the issue include, but are not limited to: Biomechanical Aspects of Sports-Related Head Injuries; Peripheral Nerve Injuries in Sport; CNS Performance Enhancing Drugs in Sport, Sleep, Recovery, and Performance in Sport; Pathophysiology of Sports-Related Concussion; Neurologic Injuries in Noncontact Sports; Neuropsychological Screening in Concussion; Neurosurgical Emergencies in Sport; Psychiatric Comorbidities in Sport; and Biomarkers and Their Role in Sport-Related Head Trauma, among others.

  • Handbook of Epigenetics

    The New Molecular and Medical Genetics
    • 2 Edición
    • Trygve O. Tollefsbol
    • Inglés
    Handbook of Epigenetics: The New Molecular and Medical Genetics, Second Edition, provides a comprehensive analysis of epigenetics, from basic biology, to clinical application. Epigenetics is considered by many to be the new genetics in that many biological phenomena are controlled, not through gene mutations, but rather through reversible and heritable epigenetic processes. These epigenetic processes range from DNA methylation to prions. The biological processes impacted by epigenetics are vast and encompass effects in lower organisms and humans that include tissue and organ regeneration, X-chromosome inactivation, stem cell differentiation, genomic imprinting, and aging. The first edition of this important work received excellent reviews; the second edition continues its comprehensive coverage adding more current research and new topics based on customer and reader reviews, including new discoveries, approved therapeutics, and clinical trials. From molecular mechanisms and epigenetic technology, to discoveries in human disease and clinical epigenetics, the nature and applications of the science is presented for those with interests ranging from the fundamental basis of epigenetics, to therapeutic interventions for epigenetic-based disorders.

  • Brain Edema

    From Molecular Mechanisms to Clinical Practice
    • 1 Edición
    • Jerome Badaut + 1 más
    • Inglés
    Brain Edema: From Molecular Mechanisms to Clinical Practice brings together the most widely recognized experts in experimental and clinical brain edema research to review the current knowledge gathered on the molecular and cellular pathophysiology and clinical management of brain edema. This timely book also discusses future directions of research and treatment. Brain edema is an integral and acutely life-threatening part of the pathophysiology of multiple cerebral and non-cerebral disorders, including traumatic brain injury, cerebral ischemia, brain tumors, cardiac arrest, altitude sickness and liver failure. Affecting millions worldwide, research over the past few years has shown that a plethora of complex molecular and cellular mechanisms contribute to this pathological accumulation of water in the brain parenchyma. In parallel, the development of new neuroimaging tools has provided a new way to examine how edema develops longitudinally and in real time, both in pre-clinical models and in patients. Despite intense research over the past few decades, therapeutic options are still limited and sometimes not effective.

  • Chronic Kidney Disease in Disadvantaged Populations

    • 1 Edición
    • Guillermo Garcia-Garcia + 2 más
    • Inglés
    Chronic Kidney Disease in Disadvantaged Populations investigates the increased incidence and prevalence of kidney disease in vulnerable populations world-wide. The volume explores the complex interactions of genetic, biologic, cultural and socioeconomic factors such as the environment, and specific health behaviors that seem to be responsible for a significant proportion of the health disparities in these communities. Each chapter is written by leading experts in the field and analyzes the prevalence and incidence of pre-dialysis kidney disease in disadvantaged populations across both developed and developing countries. In addition, each contribution analyzes differentiated risk factors and compares the disparities in access to screening, prevention strategies, treatment protocols and renal replacement therapies. Chronic Kidney Disease in Disadvantaged Populations is essential reading for residents, fellows, clinicians and biomedical researchers working in nephrology, internal medicine, and epidemiology, especially those working in areas with high concentrations of disadvantaged populations.

  • From Artemisia annua L. to Artemisinins

    The Discovery and Development of Artemisinins and Antimalarial Agents
    • 1 Edición
    • Youyou Tu
    • Inglés
    From Artemisia annua L. to Artemisinins: The Discovery and Development of Artemisinins and Antimalarial Agents is the first book that systematically introduces the origin and development of artemisinine and artemisinine-based drugs. It includes four distinct sections, including Artemisia annua L., Artemisinin, Dihydroartemisinin, and other artemisinin derivatives. Tu Youyou, the chief inventor of artemisinin, together with other members from the research team, have written a book that will be a valuable reference work for both researchers involved in the medical industry and scholars who are interested in undertaking innovative research.

  • Learning and Memory: A Comprehensive Reference

    • 2 Edición
    • John H. Byrne
    • Inglés
    Learning and Memory: A Comprehensive Reference, Second Edition, Four Volume Set is the authoritative resource for scientists and students interested in all facets of learning and memory. This updated edition includes chapters that reflect the state-of-the-art of research in this area. Coverage of sleep and memory has been significantly expanded, while neuromodulators in memory processing, neurogenesis and epigenetics are also covered in greater detail. New chapters have been included to reflect the massive increase in research into working memory and the educational relevance of memory research. No other reference work covers so wide a territory and in so much depth.

  • Dietary Fiber for the Prevention of Cardiovascular Disease

    Fiber’s Interaction between Gut Microflora, Sugar Metabolism, Weight Control and Cardiovascular Health
    • 1 Edición
    • Rodney A. Samaan
    • Inglés
    Dietary Fiber for the Prevention of Cardiovascular Disease: Fiber’s Interaction between Gut Micoflora, Sugar Metabolism, Weight Control and Cardiovascular Health compiles the most up-to-date research discoveries to provide a timely and scientific rationale for the significant impact of a fiber rich diet for the prevention of heart disease. By focusing on the science behind how fiber, both soluble and insoluble can lead to lower rates of heart disease, this important reference will educate researchers, cardiologists, medical providers and students on how to improve patients’ hearts via a fiber rich diet. Coverage includes the known mechanisms of how fiber works to reduce insulin resistance, control weight, reduce cholesterol by binding with bile, maintain stable glucose levels and influence gut microflora.

  • Western Blotting Guru

    • 1 Edición
    • Ayaz Najafov + 1 más
    • Inglés
    Western Blotting Guru provides researchers in molecular biology with a handy reference for approaching and solving challenging problems associated with immunoblotting setup and optimization. As a laboratory guide, it emphasizes the technical aspects of efficiently employing immunoblotting as a tool in molecular biology laboratories. The book covers the basic science underlying immunoblotting and detailed description of the method parameters, followed by good benchtop practices, tips and tricks for obtaining high-quality data and a detailed troubleshooting guide addressing a variety of problem types.

  • Structural and Mechanistic Enzymology

    • 1 Edición
    • Volumen 109
    • Inglés
    Structural and Mechanistic Enzymology, Volume 109, the latest release in the Advances in Protein Chemistry and Structural Biology series, is an essential resource for protein chemists. Chapters in this new volume include Collagenolytic Matrix Metalloproteinase Structure–Function Relationships: Insights from Molecular Dynamics Studies, Computational Glycobiology: Mechanistic Studies of Carbohydrate-Active Enzymes and Implication for Inhibitor Design, Computational Biochemistry─Enzyme Mechanisms Explored, and A Paradigm for C─H Bond Cleavage: Structural and Functional Aspects of Transition State Stabilization by Mandelate Racemase. This series presents new information on protocols and analysis of proteins, with each volume guest edited by leading experts in a broad range of protein-related topics. This volume presents state-of-the-art contributions, providing insights into the relationship between enzyme structure, catalysis, and function.

  • Soft Drink and Fruit Juice Problems Solved

    • 2 Edición
    • Philip Ashurst + 2 más
    • Inglés
    Soft Drinks and Fruit Juice Problems Solved, Second Edition, follows the innovative question and answer format of the first edition, presenting a quick problem-solving reference. Questions like: Does the use of a preservative in a product mean that it does not need to be pasteurized? How much deviation from ingredient specification is needed to cause a noticeable alteration in product quality? What kinds of organisms will grow in bottled waters? When is it necessary to obtain expert assistance in the event of a contamination incident? are all answered in detail. The book's new introduction covers basic questions about soft drinks, their ingredients, and packaging. Additional new chapters expand on microbiological problems, shelf life and storage, and fruit juices and nectars, as well as product nutrition and health claims. Final chapters offer soft drink and fruit juice data sources. Written by authors with extensive industrial experience, the book is an essential reference and problem-solving manual for professionals and trainees in the beverage industry.

  • Effects of Forage Feeding on Milk

    Biaoctive Compounds and Flavor
    • 1 Edición
    • Pavel Kalac
    • Inglés
    Effects of Forage Feeding on Milk: Bioactive Compounds and Flavor collates the research related to biologically active compounds associated with chain fresh/preserved temperate forages, the dairy animal, and cow´s, goat´s, and ewe´s milk and milk products. Comprised of six chapters, this book begins by presenting a brief overview of components of the chain – the forage, the milking animal, and milk. The book then addresses desirable and detrimental compounds by providing an expansive description of each compound’s chemical nature, methods of analytical determination, biological properties and effects on humans, factors affecting level in forage, effects of ensiling and haymaking, processes within the animal, content in milk and milk products, and health evaluation. The book also outlines volatiles affecting the flavor of milk and milk products, and includes a conclusion and numerous relevant references for further reading.

  • Engineering Neural Tissue from Stem Cells

    • 1 Edición
    • Stephanie Willerth
    • Inglés
    Engineering Neural Tissue from Stem Cells covers the basic knowledge needed to understand the nervous system and how existing cells can be used to create neural tissue. This book presents a broad range of topics related to the design requirements for engineering neural tissue from stem cells. It begins with the anatomy and function of the central and peripheral nervous system, also covering stem cells, their relation to the nervous system and their function in recovery after injury or disease. In addition, the book explores the role of the extracellular matrix and vasculature/immune system and biomaterials, including their suitability for neural tissue engineering applications.

  • Encyclopedia of Sustainable Technologies

    • 1 Edición
    • Inglés
    Encyclopedia of Sustainable Technologies, Eight Volume Set provides an authoritative assessment of the sustainable technologies that are currently available or in development. Sustainable technology includes the scientific understanding, development and application of a wide range of technologies and processes and their environmental implications. Systems and lifecycle analyses of energy systems, environmental management, agriculture, manufacturing and digital technologies provide a comprehensive method for understanding the full sustainability of processes. In addition, the development of clean processes through green chemistry and engineering techniques are also described. The book is the first multi-volume reference work to employ both Life Cycle Analysis (LCA) and Triple Bottom Line (TBL) approaches to assessing the wide range of technologies available and their impact upon the world. Both approaches are long established and widely recognized, playing a key role in the organizing principles of this valuable work.

  • Treating Life-Threatening Bleedings

    Development of Recombinant Coagulation Factor VIIa
    • 1 Edición
    • Ulla Hedner
    • Inglés
    Treating Life-Threatening Bleedings: Development of Recombinant Coagulation Factor VIIa provides a comprehensive understanding of the first new drug within the area of hemostasis, describing a new mechanism of action that has resulted in a modified concept of the whole hemostasis mechanism. As the treatment of life-threatening bleedings is a serious challenge for clinicians, this powerful and historic case study presents a detailed roadmap on how a new medicine can be developed, stressing the interaction between science and clinical work. The book stresses the importance of patient care in the learning process and provides new ideas on how to approach diseases and their treatment. Users will find a real world example that will act as a timely resource for those learning about, or engaged in, performing and supervising research across the biomedical sciences.

  • Board Review in Preventive Medicine and Public Health

    • 1 Edición
    • Gregory M. Schwaid
    • Inglés
    Board Review in Preventive Medicine and Public Health prepares physicians for their initial and recertification board exams in the related specialties of preventive, occupational and aerospace medicine. Formatted in a question and answer based style that imitates material on specialty exams, each question is linked to a detailed answer. The book contains over 640 question and answer sets covering areas such as general public health, health management, health law, community health, infectious disease, clinical preventive medicine, occupational medicine, aerospace medicine, environmental medicine, correctional (prison) medicine, emergency preparedness, epidemiology and biostatistics. The book is an essential board preparation for physicians with a background in the fields of preventive medicine, occupational medicine, and aerospace medicine. It is also useful for medical students, public health students and those wishing to gain an understanding of the key points in these fields.

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    A Practical Handbook
    • 1 Edición
    • Lauren Rogers
    • Inglés
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  • Viral Proteases and Their Inhibitors

    • 1 Edición
    • Satya Prakash Gupta
    • Inglés
    Viral Proteases and Their Inhibitors provides a thorough examination of viral proteases from their molecular components, to therapeutic applications. As information on three dimensional structures and biological functions of these viral proteases become known, unexpected protein folds and unique mechanisms of proteolysis are realized. This book investigates how this facilitates the design and development of potent antiviral agents used against life-threatening viruses. Users will find descriptions of each virus that detail the structure and function of viral proteases, discuss the design and development of inhibitors, and analyze the structure-activity relationships of inhibitors. This book is ideal biochemists, virologists and those working on antiviral agents.

  • Sittig's Handbook of Toxic and Hazardous Chemicals and Carcinogens

    • 7 Edición
    • Richard P. Pohanish
    • Inglés
    Sittig's Handbook of Toxic and Hazardous Chemicals and Carcinogens, Seventh Edition, has proven to be a reliable, accessible, must-have reference on hazardous materials for over thirty years. This updated and revised seventh edition is the most comprehensive listing of the hazardous chemicals commonly used, transported, and regulated in industry and the workplace. Information is the most vital resource anyone can have when dealing with potential hazardous substance accidents, spillages, fires, or acts of terror. It is also essential for the safe day-to-day operation of chemical processes and environmental protection. Sittig's Handbook provides extensive data for over 2,200 chemicals in a uniform format, enabling fast and accurate decisions in any situation. The chemicals are presented alphabetically and classified as a carcinogen, hazardous substance, hazardous waste, or toxic pollutant. This new edition contains expanded and reviewed information for each chemical listed (including chemicals classified as WMD) and has been updated to keep pace with world events, standards, and regulations. This seventh edition includes over 100 new records, and every single record has been checked and updated as necessary.

  • Thiamine Deficiency Disease, Dysautonomia, and High Calorie Malnutrition

    • 1 Edición
    • Derrick Lonsdale + 1 más
    • Inglés
    Thiamine Deficiency Disease, Dysautonomia, and High Calorie Malnutrition explores thiamine and how its deficiency affects the functions of the brainstem and autonomic nervous system by way of metabolic changes at the level of the mitochondria. Thiamine deficiency derails mitochondrial oxidative metabolism and gives rise to the classic disease of beriberi that, in its early stages, can be considered the prototype for a set of disorders that we now recognize as dysautonomia. This book represents the life’s work of the senior author, Dr. Derrick Lonsdale, and a recent collaboration with his co-author Dr. Chandler Marrs.

  • DNA Repair Enzymes: Structure, Biophysics, and Mechanism

    • 1 Edición
    • Volumen 592
    • Inglés
    DNA Repair Enzymes, Part B, Volume 592 is the latest volume in the Methods in Enzymology series and the first part of a thematic that focuses on DNA Repair Enzymes. Topics in this updated volume include MacroBac: New Technologies for Robust and Efficient Large-Scale Production of Recombinant Multiprotein Complexes, Production and Assay of Recombinant Multisubunit Chromatin Remodeling Complexes, Analysis of Functional Dynamics of Modular Multidomain Proteins by SAXS and NMR, the Use of Single-Cysteine Variants for Trapping Transient States in DNA Mismatch Repair, and Structural Studies of RNases H2 as an Example of Crystal Structure Determination of Protein-Nucleic Acid Complexes.

  • Key Advances in Clinical Informatics

    Transforming Health Care through Health Information Technology
    • 1 Edición
    • Aziz Sheikh + 3 más
    • Inglés
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  • Chemical Contaminants and Residues in Food

    • 2 Edición
    • D Schrenk + 1 más
    • Inglés
    Chemical Contaminants and Residues in Food, Second Edition is an invaluable tool for all industrial and academic researchers involved with food safety, from industry professionals responsible for producing safe food, to chemical analysts involved in testing the final products. This updated edition is expanded to cover the latest research and emerging issues, and has additional information useful for food safety testing. Written by an international team of expert contributors, this edition explores the entire food chain, acting as a roadmap for further research.

  • Food Bioconversion

    • 1 Edición
    • Volumen 2
    • Alexandru Mihai Grumezescu + 1 más
    • Inglés
    Food Bioconversion, Volume Two in the Handbook of Food Bioengineering series is an interdisciplinary resource of fundamental information on waste recovery and biomaterials under certain environmental conditions. The book provides information on how living organisms can be used to transform waste into compounds that can be used in food, and how specialized living cells in plants, animals and water can convert the most polluting agents into useful non-toxic products in a sustainable way. This great reference on the bioconversion of industrial waste is ideal in a time when food resources are limited and entire communities starve.

  • Matrix Metalloproteinases and Tissue Remodeling in Health and Disease: Target Tissues and Therapy

    • 1 Edición
    • Volumen 148
    • Inglés
    Matrix Metalloproteinases and Tissue Remodeling in Health and Disease: Target Tissues and Therapy, Volume, Volume 148, the latest volume in the Progress in Molecular Biology and Translational Science series covers a variety of timely topics, with chapters focusing on The Role of Matrix Metalloproteinases in Development, Repair, and Destruction of the Lungs, Matrix Metalloproteinases in Kidney Disease: Role in Pathogenesis and Potential as a Therapeutic Target, Regulation of Matrix Metalloproteinase in the Pathogenesis of Diabetic Retinopathy, Matrix Metalloproteinases in Normal Pregnancy and Preeclampsia, and Matrix Metalloproteinases, Neural Extracellular Matrix, and Central Nervous System Pathology. This volume is the second part of a thematic on matrix metalloproteinases and tissue remodeling in health and disease. It focuses on the role of MMPs in other systems, target tissues, and pathological disorders and the potential benefits of MMP inhibitors in various disorders.

  • Erythropoietin

    • 1 Edición
    • Volumen 105
    • Inglés
    Erythropoietin, Volume 105, the latest release in the Vitamins and Hormones series first published in 1943, and the longest-running serial published by Academic Press, provides up-to-date information on crystal structures and basic structural studies on neurotrophins and their receptors, neurotrophin functions and the biological actions of neurotrophins related to clinical conditions and disease. Topics covered in this new volume include Erythropoietin Receptor Structural Domains, Analysis of the Asymmetry of Activated EPO Receptor Enables Designing Small Molecule Agonists, Endogenous Erythropoietin, Erythropoietin Receptor Signaling and Lipid Rafts, and Erythropoietin and Hypothalamic-Pituita... Axis. Each thoroughly reviewed volume focuses on a single molecule or disease that is related to vitamins or hormones, with the topic broadly interpreted to include related substances, such as transmitters, cytokines, growth factors and others. This volume documents the activities of this vital molecule, also describing the structure and function of erythropoietin and its receptor.

  • Rhythmic Stimulation Procedures in Neuromodulation

    • 1 Edición
    • James R. Evans + 1 más
    • Inglés
    Rhythmic Stimulation Procedures in Neuromodulation offers a unique approach to rhythm-related stimulation as it pertains to modulating neural functioning, with the goal of alleviating symptoms of mental disorder. Rhythm and related concepts (frequency, resonance, entrainment) are thought by many to be closely linked to human health and disease. Neurologists and clinical psychologists facilitate neuroplasticity by using pulsed (rhythmic) sensory or electromagnetic stimulation—a group of techniques broadly referred to as neuromodulation. This edited volume describes details of rhythm-related neuromodulation techniques, and experts in the field have detailed the pros and cons of each approach, citing both clinical and scientific support. Each technique chapter provides a detailed description of the procedure, a rationale for application with specific populations, discussion of similarities/differe... relative to other approaches, and support for efficacy. This volume offers readers a historical overview of the roles of rhythm and dysrhythmia in health and disease, including examples of past and present therapeutic uses of rhythmic stimulation, entrainment, and/or modification. It also facilitates speculation about potential developments in rhythm-related methods for the future of mental health. Few books published in the general area of rhythm have focused on the scientific study of the significance of biological rhythms.

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