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Elsevier

Libros en Ciencias de la Vida

  • An Introduction to Ethical, Safety and Intellectual Property Rights Issues in Biotechnology

    • 1 Edición
    • Padma Nambisan
    • Inglés
    An Introduction to Ethical, Safety and Intellectual Property Rights Issues in Biotechnology provides a comprehensive look at the biggest technologies that have revolutionized biology since the early 20th century, also discussing their impact on society. The book focuses on issues related to bioethics, biosafety and intellectual property rights, and is written in an easy-to-understand manner for graduate students and early career researchers interested in the opportunities and challenges associated with advances in biotechnology. Important topics covered include the Human Genome Project, human cloning, rDNA technology, the 3Rs and animal welfare, bioterrorism, human rights and genetic discrimination, good laboratory practices, good manufacturing practices, the protection of biological material and much more. Full of relevant case studies, practical examples, weblinks and resources for further reading, this book offers an essential and holistic look at the ways in which biotechnology has affected our global society.

  • The Rewiring Brain

    A Computational Approach to Structural Plasticity in the Adult Brain
    • 1 Edición
    • Arjen van Ooyen + 1 más
    • Inglés
    The adult brain is not as hard-wired as traditionally thought. By modifying their small- or large-scale morphology, neurons can make new synaptic connections or break existing ones (structural plasticity). Structural changes accompany memory formation and learning, and are induced by neurogenesis, neurodegeneration and brain injury such as stroke. Exploring the role of structural plasticity in the brain can be greatly assisted by mathematical and computational models, as they enable us to bridge the gap between system-level dynamics and lower level cellular and molecular processes. However, most traditional neural network models have fixed neuronal morphologies and a static connectivity pattern, with plasticity merely arising from changes in the strength of existing synapses (synaptic plasticity). In The Rewiring Brain, the editors bring together for the first time contemporary modeling studies that investigate the implications of structural plasticity for brain function and pathology. Starting with an experimental background on structural plasticity in the adult brain, the book covers computational studies on homeostatic structural plasticity, the impact of structural plasticity on cognition and cortical connectivity, the interaction between synaptic and structural plasticity, neurogenesis-related structural plasticity, and structural plasticity in neurological disorders. Structural plasticity adds a whole new dimension to brain plasticity, and The Rewiring Brain shows how computational approaches may help to gain a better understanding of the full adaptive potential of the adult brain. The book is written for both computational and experimental neuroscientists.

  • Stored-Product Insect Resource

    • 1 Edición
    • David Hagstrum + 1 más
    • Inglés
    Accurate species identification is essential for effective pest management. Stored-Product Insect Resource is the most multifaceted, comprehensive guide available to information on 1,663 insect species associated with stored products. This book covers 1,105 commodities and more than 9,200 different insect-commodity associations. A broad consideration of the species associated with stored products is important, because many unfamiliar species are being encountered as a result of extensive international trade. Information on 468 species of natural enemies provides a fuller understanding of the potential for biological control of stored-product insects. Commodities that are likely to be infested are listed for each insect species, and information on the suitability of some commodities as food is also reviewed. This book includes a catalog that can help locate pictures and keys to identify stored-product insects. Each author has more than 30 years of research experience and has taught stored-product entomology. This title is a useful supplement to the textbook Fundamentals of Stored-Product Entomology, also by Hagstrum and Subramanyam. Stored-Product Insect Resource will be an important desktop directory for identifying and finding information on stored-product insects.

  • DNA Repair Enzymes: Cell, Molecular, and Chemical Biology

    • 1 Edición
    • Volumen 591
    • Inglés
    DNA Repair Enzymes, Part A, Volume 591 is the latest volume in the Methods in Enzymology series and the first part of a thematic that focuses on DNA repair enzymes. Topics in this new release include chapters on the Optimization of Native and Formaldehyde iPOND Techniques for Use in Suspension Cells, the Proteomic Analyses of the Eukaryotic Replication Machinery, DNA Fiber Analysis: Mind the Gap!, Comet-FISH for Ultrasensitive Strand-Specific Detection of DNA Damage in Single Cells, Examining DNA Double-Strand Break Repair in a Cell Cycle-Dependent Manner, Base Excision Repair Variants in Cancer, and Fluorescence-Based Reporters for Detection of Mutagenesis in E. coli.

  • Beyond Agricultural Impacts

    Multiple Perspectives on Climate Change and Agriculture in Africa
    • 1 Edición
    • Nkulumo Zinyengere + 3 más
    • Inglés
    Beyond Agricultural Impacts: Multiple Perspectives on Climate Change in Africa presents the theories and methods commonly applied in climate change assessment from various locations in Africa, also inspiring further research that addresses the broad spectrum of societal impacts that result from altered climate status. Using case studies, the work provides insights into climate change impacts and adaptation with a lens on vulnerable groups in African agriculture, e.g. smallholder crop and livestock farmers, women and youth. The book also highlights areas of further interest in climate change and agriculture research in Africa, all done through views from multiple disciplines in the agriculture and climate change nexus.

  • Biomedical Engineering in Gastrointestinal Surgery

    • 1 Edición
    • Armin Schneider + 1 más
    • Inglés
    Biomedical Engineering in Gastrointestinal Surgery is a combination of engineering and surgical experience on the role of engineering in gastrointestinal surgery. There is currently no other book that combines engineering and clinical issues in this field, while engineering is becoming more and more important in surgery. This book is written to a high technical level, but also contains clear explanations of clinical conditions and clinical needs for engineers and students. Chapters covering anatomy and physiology are comprehensive and easy to understand for non-surgeons, while technologies are put into the context of surgical disease and anatomy for engineers. The authors are the two most senior members of the Institute for Minimally Invasive Interdisciplinary Therapeutic Interventions (MITI), which is pioneering this kind of collaboration between engineers and clinicians in minimally invasive surgery. MITI is an interdisciplinary platform for collaborative work of surgeons, gastroenterologists, biomedical engineers and industrial companies with mechanical and electronic workshops, dry laboratories and comprehensive facilities for animal studies as well as a fully integrated clinical "OR of the future".

  • Animal Models for the Study of Human Disease

    • 2 Edición
    • P. Michael Conn
    • Inglés
    Animal Models for the Study of Human Disease, Second Edition, provides needed information on model sharing, animal alternatives, animal ethics and access to databanks of models, bringing together common descriptions of models for busy researchers across biomedical and biological sciences. Offering easily searchable advantages and disadvantages for each animal model and organized by disease topics, this resource aids researchers in finding the best animal model for research in human disease.

  • Food Biosynthesis

    • 1 Edición
    • Volumen 1
    • Alexandru Mihai Grumezescu + 1 más
    • Inglés
    Food Biosynthesis, Volume One in the Handbook of Food Bioengineering series, describes the main aspects related to the biological production of synthetic ingredients and natural foods, highlighting the impact of bacteria and plants in the biosynthesis of key food components. Biosynthesis methods could help solve issues like food shortages, providing consumers with preferred ‘natural’ food options. This book represents how biologically synthesized ingredients, such as vanilla flavoring, soy, milk and egg substitutes can be utilized as a desired option future foods. It is ideal for scientists and researchers who want to improve their knowledge on the field of food biosynthesis.

  • Dairy in Human Health and Disease across the Lifespan

    • 1 Edición
    • Ronald Ross Watson + 2 más
    • Inglés
    Dairy in Human Health and Disease across the Lifespan addresses the contribution of milk to the human diet and health throughout the life span. This comprehensive book is divided into three sections and presents a balanced overview of dairy’s impact on nutrition from infancy to adulthood. Summaries capture the most salient points of each chapter, and the book provides coverage of dairy as a functional food in health and disease.

  • Psychometrics and Psychological Assessment

    Principles and Applications
    • 1 Edición
    • Carina Coulacoglou + 1 más
    • Inglés
    Psychometrics and Psychological Assessment: Principles and Applications reports on contemporary perspectives and models on psychological assessment and their corresponding measures. It highlights topics relevant to clinical and neuropsychological domains, including cognitive abilities, adaptive behavior, temperament, and psychopathology.More... the book examines a series of standard as well as novel methods and instruments, along with their psychometric properties, recent meta-analytic studies, and their cross-cultural applications.

  • Nutrients in Dairy and Their Implications for Health and Disease

    • 1 Edición
    • Ronald Ross Watson + 2 más
    • Inglés
    Nutrients in Dairy and Their Implications for Health and Disease addresses various dairy products and their impact on health. This comprehensive book is divided into three sections and presents a balanced overview of the health benefits of milk and milk products. Summaries capture the most salient points of each chapter, and the importance of milk and its products as functional foods is addressed throughout.

  • Advances in Clinical Chemistry

    • 1 Edición
    • Volumen 81
    • Inglés
    Advances in Clinical Chemistry, Volume 81, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. New to this latest release are chapters that cover Microparticles in Chronic Heart Failure, Peptide Antibodies in Clinical Laboratory Diagnostics, Measurement and Clinical Utility of βCTX in Serum and Plasma, Human Papillomavirus and its Testing Assays, Cervical Cancer Screening, and Vaccination, and Physical Exercise and DNA Injury: Good or Evil? The serial presents the latest technologies related to the field of clinical chemistry, and is the benchmark for novel analytical approaches in the clinical laboratory.

  • Molecular Approach to Cancer Management

    • 1 Edición
    • Gajanan V. Sherbet
    • Inglés
    Molecular Approach to Cancer Management discusses molecular mechanisms of cancer initiation, growth and secondary spread, emphasizing how this information can be used to devise new modes of treatment of cancer, especially in combatting secondary spread. The book addresses the basic concepts relating to cancer biology, the genetic determinants, and the signal transduction cascades associated with tumor growth, EMT, stem cell maintenance and propagation, and invasion and metastasis. The salient features of the signaling systems that are amenable to targeted manipulation are emphasized to facilitate research and development in the design of novel therapies and for the planning of new trials. This book is the only unique volume with coverage of topics that target therapy. As such, it is a valuable source for cancer researchers, molecular oncologists and members of the biomedical field who are interested in knowing more about molecular approaches to cancer therapy.

  • Starch-Based Materials in Food Packaging

    Processing, Characterization and Applications
    • 1 Edición
    • Silvia Elena Barbosa + 4 más
    • Inglés
    Starch-Based Materials in Food Packaging: Processing, Characterization and Applications comprises an experimental approach related to the processing and characterization of biopolymers derived from different starches. The book includes fundamental knowledge and practical applications, and it also covers valuable experimental case studies. The book not only provides a comprehensive overview concerning biodegradable polymers, but also supplies the new trends in their applications in food packaging. The book is focused toward an ecological proposal to partially replace synthetics polymers arising from non-renewable sources for specific applications. This tender implies the protection of natural resources. Thus, the use of starch as feedstock to develop biodegradable materials is a good and promissory alternative. With the contributions and collaboration of experts in the development and study of starch based materials, this book demonstrates the versatility of this polysaccharide and its potential use.

  • Essentials of Noncoding RNA in Neuroscience

    Ontogenetics, Plasticity of the Vertebrate Brain
    • 1 Edición
    • Davide De Pietri Tonelli
    • Inglés
    Essentials of Noncoding RNA in Neuroscience: Ontogenetics, Plasticity of the Vertebrate Brain focuses on the role of miRNAs in neurogenesis, gliogenesis, neuronal network formation, and the cell biology of forebrain development. The important role miRNAs play in neuronal maturation, neocortex function, and in some neurodevelopmental disorders is discussed, as are the computational challenges and methods used in the identification of miRNA targets. This book is a valuable reference for neuroscientists who wish to better understand the role of miRNAs in complex processes. It is of strong interest to those working to develop enabling technologies to detect and monitor miRNA expression and function, and to evaluate its roles in neural progenitor proliferation/differ... neuronal plasticity, and learning and memory.

  • Models of Seizures and Epilepsy

    • 2 Edición
    • Asla Pitkänen + 3 más
    • Inglés
    Models of Seizures and Epilepsy, Second Edition, is a valuable, practical reference for investigators who are searching for the most appropriate laboratory models to address key questions in the field. The book also provides an important background for physicians, fellows, and students, offering insight into the potential for advances in epilepsy research as well as R&D drug development. Contents include the current spectrum of models available to model different epilepsy syndromes, epilepsy in transgenic animals, comorbidities in models of epilepsy, and novel technologies to study seizures and epilepsies in animals.

  • Milestones in Immunology

    Based on Collected Papers
    • 1 Edición
    • Domenico Ribatti
    • Inglés
    Milestones in Immunology: Based on Collected Papers contains scientific milestones relating to the history of medicine over the past two centuries. The book highlights the contributions of pioneering scientists whose discoveries have paved the way for researchers working in the field of immunology. As the science of immunology grew from knowledge that survivors of common infectious diseases rarely contracted them again, the book uses this as a central thesis, helping readers understand how the adaptive immune system aids in defense against pathogens. In addition, the book covers special fields, such as immunohistochemistry... immunogenetics and immunopathology. For the past century, immunology has fascinated and inspired some of the greatest scientists of our time. Numerous Nobel Prizes have been awarded for fundamental discoveries in immunology, from Paul Ehrlich’ work on antibodies (1908) to the studies of Zinkernagel and Doherty (1986) elucidating mechanisms of cell-mediated immunity.

  • Microbiology and Molecular Diagnosis in Pathology

    A Comprehensive Review for Board Preparation, Certification and Clinical Practice
    • 1 Edición
    • Audrey Wanger + 5 más
    • Inglés
    Microbiology and Molecular Diagnosis in Pathology: A Comprehensive Review for Board Preparation, Certification and Clinical Practice reviews all aspects of microbiology and molecular diagnostics essential to successfully passing the American Board of Pathology exam. This review book will also serve as a first resource for residents who want to become familiar with the diagnostic aspects of microbiology and molecular methods, as well as a refresher course for practicing pathologists. Opening chapters discuss issues of laboratory management, including quality control, biosafety, regulations, and proper handling and reporting of laboratory specimens. Review chapters give a quick overview of specific clinical infections as well as different types of bacteria, viruses, fungal infections, and infections caused by parasites. Following these, coverage focuses on diagnostic tools and specific tests: media for clinical microbiology, specific stains and tests for microbial identifications, susceptibility testing and use of antimicrobial agents, tests for detecting antibodies, antigens, and microbial infections. Two final chapters offer overviews on molecular diagnostics principles and methods as well as the application of molecular diagnostics in clinical practice.

  • Agriculture to Zoology

    Information Literacy in the Life Sciences
    • 1 Edición
    • Jodee L Kuden + 2 más
    • Inglés
    Agriculture to Zoology: Information Literacy in the Life Sciences sets the stage for purposefully integrating information literacy activities within the subject-specific content of the life sciences. The book is written for librarians and other professionals who teach information literacy skills, especially those in the science disciplines, and most especially the life sciences. It is also intended to be helpful to secondary school teachers, college faculty who teach life science-related subjects, library school students, and others interested in information literacy and science education. Anyone wanting to learn more about the Earth’s life sciences, from citizen to scientist, will benefit as well. The book’s seven chapters fill a gap with varying perspectives of literacy instruction in the life sciences and include resources identified by academic librarians as important for use in subject-specific research in higher education. Contributors are longtime specialists in the fields of the life sciences, science and information literacy, scientific and electronic communication, assessment, and more, including Arctic and Antarctic information.

  • Nitric Oxide (Donor/Induced) in Chemosensitization

    • 1 Edición
    • Volumen 1
    • Benjamin Bonavida
    • Inglés
    Nitric Oxide as a Chemosensitizing Agent, Volume One is the first book to describe several reviews by authoritative scientists and clinicians on novel findings in the reversal of drug resistant cancers by the combination treatment of Nitric Oxide and sub toxic concentrations of chemotherapeutic drugs that have been reported in both in vitro, in vivo and preclinical models. The book describes the various underlying chemical, molecular and genetic mechanisms by which NO and NO reactive species mediate the anti-cancer activity, thus reducing the threshold of drug resistance and enabling chemo therapeutic drugs to induce their cytotoxic activity and reversal of resistance. This book exposes scientists and clinicians to this highly beneficial topic for research investigations and pharmaceutical companies to new avenues for R&D. It is a valuable resource for cancer researchers, oncologists and members of several areas of the biomedical field who are interested in understanding how to use Nitric Oxide as a sensitizing agent for chemotherapy.

  • RNA Modification

    • 1 Edición
    • Volumen 41
    • Inglés
    RNA Modification, Volume 41 examines the powerful ability to regulate the function of RNA molecules or modify the message transmitted by RNA molecules. Chapters in this newly released volume include The Importance of Being Modified: Modifications Shape RNA Function through Chemistry, Structure and Dynamics, The evolution of multi-substrate specificity by RNA modification enzymes, TrmD: a methyl transferase for tRNA methylation with m1G37, Structures and activities of the Elongator complex and its co-factors, RNA pseudouridylation: Mechanism and Function, The activity of 5’3' exonucleases on hypo modified tRNA substrates and other structured RNAs, and the Synthesis, heterogeneity and function of post-transcriptional nucleotide modifications in eukaryotic ribosomal RNAs. This field has recently seen a very rapid progress in the understanding of the mechanism and enzymes involved in RNA modification. This volume presents some of the most recent advances in the identification and function of enzymes involved in modifying RNA molecules.

  • Biomechanics of Living Organs

    Hyperelastic Constitutive Laws for Finite Element Modeling
    • 1 Edición
    • Yohan Payan + 1 más
    • Inglés
    Biomechanics of Living Organs: Hyperelastic Constitutive Laws for Finite Element Modeling is the first book to cover finite element biomechanical modeling of each organ in the human body. This collection of chapters from the leaders in the field focuses on the constitutive laws for each organ. Each author introduces the state-of-the-art concerning constitutive laws and then illustrates the implementation of such laws with Finite Element Modeling of these organs. The focus of each chapter is on instruction, careful derivation and presentation of formulae, and methods. When modeling tissues, this book will help users determine modeling parameters and the variability for particular populations. Chapters highlight important experimental techniques needed to inform, motivate, and validate the choice of strain energy function or the constitutive model. Remodeling, growth, and damage are all covered, as is the relationship of constitutive relationships of organs to tissue and molecular scale properties (as net organ behavior depends fundamentally on its sub components). This book is intended for professionals, academics, and students in tissue and continuum biomechanics.

  • Kidney Transplantation, Bioengineering, and Regeneration

    Kidney Transplantation in the Regenerative Medicine Era
    • 1 Edición
    • Giuseppe Orlando + 2 más
    • Inglés
    Kidney Transplantation, Bioengineering, and Regeneration: Kidney Transplantation in the Regenerative Medicine Era investigates how the field of regenerative medicine is changing the traditional premises of solid organ transplantation, specifically within the field of kidney transplantation. In Section 1, chapters illustrate the state of the art in kidney transplantation as well as the research behind the bioengineering and regeneration of kidney organoids for therapeutic renal replacement. In Section II, chapters catalog the technologies that are being developed and the methods that are being implemented to bioengineer or regenerate kidneys in order to restore function, while critically highlighting those technological advances which hold the most promise. The book thus encompasses clinical renal transplantation, tissue engineering, biomaterial sciences, stem cell biology, and developmental biology, as they are all applied to the kidney.

  • Toxicology: What Everyone Should Know

    • 1 Edición
    • Aalt Bast + 1 más
    • Inglés
    Toxicology: What Everyone Should Know is an essential reference for anyone looking for an entry into this fascinating field of study. This innovative book describes important discoveries in toxicology through the ages, explores their historical and sociological impacts, and shows how they still influence recent, state-of-the-art developments. In addition, the book shows how these developments are extrapolated into public and political perceptions on risks and the regulatory consequences, emphasizing environmental issues, such as manmade and natural chemicals, their interaction and impact, nutrition, and drugs. Users will find a cutting-edge approach to nutritional and combinatorial toxicology, risk evaluation modeling and the benefits of chemicals exposure (nutrition versus man-made chemicals), environmental health, and legislative frameworks to control the public’s chemical exposure. This is an essential reference for those looking for an introduction to toxicology, its past, and exciting future.

  • The Future Rice Strategy for India

    • 1 Edición
    • Samarendu Mohanty + 6 más
    • Inglés
    The Future Rice Strategy for India presents forward-looking insights toward achieving sustainable development of the rice sector, ensuring future food and nutritional security. As a staple food for many in India, including the economically disadvantaged, there are many concerns that affect the development of rice sector. Facing issues from environmental demands to economic stagnation, access to food, food inflation, and the Food Security Act (demand – supply – distribution of rice) achieving sustainability in production and exports is an important and urgent challenge. Using case studies to illustrate existing and potential issues, challenges and solutions, The Future Rice Strategy for India presents key strategic options while considering the implicit consequences. In addition, the findings enrich the strategy and policy formulation considerations for the role of rice in the country. This multidisciplinary approach features the expertise of rice scientists covering different aspects of rice sector; from breeding to consumer preferences and markets and trade.

  • A Comprehensive and Practical Guide to Clinical Trials

    • 1 Edición
    • Delva Shamley + 1 más
    • Inglés
    A Comprehensive and Practical Guide to Clinical Trials provides an overview of the entire process of clinical research in one thorough and easy-to-read handbook that offers those involved in clinical research a clear understanding of how the components of a study are related. It focuses on the practical aspects of the preparation and execution of a clinical trial and offers tools and resources to help the entire team understand how their responsibilities tie together with the tasks and duties of other members. This allows for better planning and prioritization, and can lead to more effective and successful clinical trials. With practical examples, checklists and forms, this book is a useful guide for planning and conducting clinical trials from beginning to end.

  • Alpha-1-antitrypsin Deficiency

    Biology, Diagnosis, Clinical Significance, and Emerging Therapies
    • 1 Edición
    • Noor Kalsheker + 1 más
    • Inglés
    Alpha-1-antitrypsin Deficiency: Biology, Diagnosis, Clinical Significance, and Emerging Therapies is the authoritative reference on AATD, providing standards for diagnosis, monitoring, treatment and appropriate avenues of research. The book covers the disease from basic biology and epidemiology, to clinical impact, and includes the understanding of the natural history of the disease and the significant advances that have been made in the last 20 years, including the three-dimensional structure of the molecule, its broad biological activity and improved therapeutic options, including replacement therapy and gene therapy. The editors have recruited international experts in the field to contribute evidence-based chapters and insights on future developments in the understanding of this disease.

  • Physiology of the Cladocera

    • 2 Edición
    • Nikolai N. Smirnov
    • Inglés
    Approx.402 pages

  • Biomarkers in Inborn Errors of Metabolism

    Clinical Aspects and Laboratory Determination
    • 1 Edición
    • Uttam Garg + 1 más
    • Inglés
    Biomarkers of Inborn Errors in Metabolism: Clinical Aspects and Laboratory Determination is structured around the new reality that laboratory testing and biomarkers are an integral part in the diagnosis and treatment of inherited metabolic diseases. The book covers currently used biomarkers as well as markers that are in development. Because biomarkers used in the initial diagnosis of disease may be different than the follow-up markers, the book also covers biomarkers used in both the prognosis and treatment of inherited metabolic disorders. With the introduction of expanded new-born screening for inborn metabolic diseases, an increasing numbers of laboratories are involved in follow-up confirmatory testing. The book provides guidance on laboratory test selection and interpreting results in patients with suspected inherited metabolic diseases. The book provides comprehensive guidance on patient diagnosis and follow-up through its illustrative material on metabolic pathways, genetics and pathogenesis, treatment and prognosis of inherited metabolic diseases, along with essential information on clinical presentation. Each chapter is organized with a uniform, easy-to-follow format: a brief description of the disorder and pathway; a description of treatment; biomarkers for diagnosis; biomarkers followed for treatment efficacy; biomarkers followed for disease progression; confounding conditions that can either: affect biomarker expression or mimic IEMs; other biomarkers: less established, future.

  • Conservation for the Anthropocene Ocean

    Interdisciplinary Science in Support of Nature and People
    • 1 Edición
    • Phillip S. Levin + 1 más
    • Inglés
    Conservation for the Anthropocene Ocean: Interdisciplinary Science in Support of Nature and People emphasizes strategies to better connect the practice of marine conservation with the needs and priorities of a growing global human population. It conceptualizes nature and people as part of shared ecosystems, with interdisciplinary methodologies and science-based applications for coupled sustainability. A central challenge facing conservation is the development of practical means for addressing the interconnectedness of ecosystem health and human well-being, advancing the fundamental interdisciplinary science that underlies conservation practice, and implementing this science in decisions to manage, preserve, and restore ocean ecosystems. Though humans have intentionally and unintentionally reshaped their environments for thousands of years, the scale and scope of human influence upon the oceans in the Anthropocene is unprecedented. Ocean science has increased our knowledge of the threats and impacts to ecological integrity, yet the unique scale and scope of changes increases uncertainty about responses of dynamic socio-ecological systems. Thus, to understand and protect the biodiversity of the ocean and ameliorate the negative impacts of ocean change on people, it is critical to understand human beliefs, values, behaviors, and impacts. Conversely, on a human-dominated planet, it is impossible to understand and address human well-being and chart a course for sustainable use of the oceans without understanding the implications of environmental change for human societies that depend on marine ecosystems and resources. This work therefore presents a timely, needed, and interdisciplinary approach to the conservation of our oceans.

  • Choroidal Disorders

    • 1 Edición
    • Jay Chhablani + 1 más
    • Inglés
    Choroidal Disorders provides an overview on various chorioretinal disorders with a special emphasis on choroidal imaging. As our understanding of the choroid has significantly improved with the development of advanced optical coherence tomography (OCT) and its role in posterior segment diseases is gaining new significance, this book focuses on the related improvements, diagnostic capabilities, management and prognosis of various chorioretinal disorders. It covers conventional techniques, such as ultrasonography and indocyanine green angiography as well as the most advanced techniques, including enhanced depth imaging OCT, swept source OCT, and OCT angiography.

  • Seaweed Polysaccharides

    Isolation, Biological and Biomedical Applications
    • 1 Edición
    • Jayachandran Venkatesan + 2 más
    • Inglés
    Seaweed Polysaccharides: Isolation, Biological, and Biomedical Applications examines the isolation and characterization of algal biopolymers, including a range of new biological and biomedical applications. In recent years, significant developments have been made in algae-based polymers (commonly called polysaccharides), and in biomedical applications such as drug delivery, wound dressings, and tissue engineering. Demand for algae-based polymers is increasing and represent a potential—very inexpensive—resource for these applications. The structure and chemical modification of algal polymers are covered, as well as the biological properties of these materials – including antithrombic, anti-inflammatory, anticoagulant, and antiviral aspects. Toxicity of algal biopolymers is also covered. Finally, the book introduces and explains real world applications of algal-based biopolymers in biomedical applications, including tissue engineering, drug delivery, and biosensors. This is the first book to cover the extraction techniques, biomedical applications, and the economic perspective of seaweed polysaccharides. It is an essential text for researchers and industry professionals looking to work with this renewable resource.

  • Irradiation for Quality Improvement, Microbial Safety and Phytosanitation of Fresh Produce

    • 1 Edición
    • Rivka Barkai-Golan + 1 más
    • Inglés
    Irradiation for Quality Improvement, Microbial Safety and Phytosanitation of Fresh Produce presents the last six and a half decades of scientific information on the topic. This book emphasizes proven advantages of ionizing irradiation over the commonly used postharvest treatments for improving postharvest life of fresh fruits and vegetables to enhance their microbial safety. This reference is intended for a wide range of scientists, researchers, and students in the fields of plant diseases and postharvest diseases of fruits and vegetables. It is a means for disease control to promote food safety and quality for the food industry and can be used in food safety and agriculture courses.

  • Fragile X Syndrome

    From Genetics to Targeted Treatment
    • 1 Edición
    • Rob Willemsen + 1 más
    • Inglés
    Fragile X Syndrome: From Genetics to Targeted Treatment provides a structured overview of the molecular and clinical background of the disorder as well as treatment options. The book discusses the detailed molecular information on each of the pathways involved with sufficient details for all whose research touches this pathway. It provides a state-of-the-art update on all clinical aspects associated with this syndrome, including phenotype, diagnostics and epidemiology. It also includes an overview of the lessons learned from the preclinical research and pioneering trials on the fragile X syndrome for the investigators involved in clinical trials of neurodevelopmental disorders. This book is written for academic researchers, pharmaceutical investigators, and clinicians in the field who work on the disorder, and for researchers involved in clinical trials of the fragile X syndrome or related disorders. “This fascinating book, edited by Rob Willemsen and Frank Kooy, summarizes the current knowledge of the molecular aspects of fragile X syndrome (FXS), andthe potential for therapies resulting from this knowledge...Particul... interesting is a review “fragile X research from a parental perspective,” which summarizes the results of an international survey of the attitudes of families with FXS relatives towards research…This book is also an essential reference book for genetic counselors...The book provides counselors with the necessary biological background for proper explanations to the relatives of FXS patients. Many parents acquire a substantial knowledge of the conditions afflicting their children. The book will be helpful for both families and counselors to manage the expectations of families participating in clinical trials…In conclusion, this book is essential for everyone who is involved in the diagnosis and treatment of FXS patients.” - European Journal of Human Genetics (September 2018)

  • Yogurt in Health and Disease Prevention

    • 1 Edición
    • Nagendra P. Shah
    • Inglés
    Yogurt in Health and Disease Prevention examines the mechanisms by which yogurt, an important source of micro- and macronutrients, impacts human nutrition, overall health, and disease. Topics covered include yogurt consumption’s impact on overall diet quality, allergic disorders, gastrointestinal tract health, bone health, metabolic syndrome, diabetes, obesity, weight control, metabolism, age-related disorders, and cardiovascular health. Modifications to yogurt are also covered in scientific detail, including altering the protein to carbohydrate ratios, adding n-3 fatty acids, phytochemical enhancements, adding whole grains, and supplementing with various micronutrients. Prebiotic, probiotic, and synbiotic yogurt component are also covered to give the reader a comprehensive understanding of the various impacts yogurt and related products can have on human health.

  • Functional Neural Transplantation IV

    Translation to Clinical Application, Part B
    • 1 Edición
    • Volumen 231
    • Inglés
    Functional Neural Transplantation IV: Translation to Clinical Application, Part B, Volume 231 provides the current status of cell transplantation in the nervous system, focusing on the conditions for achieving structural repair and functional recovery. New to this edition are chapters on Plasticity and Regeneration in the Injured Spinal Cord After Cell Transplantation Therapy, Transplantation of GABAergic Interneurons for Cell-Based Therapy, Rebuilding CNS Inhibitory Circuits to Control Chronic Neuropathic Pain and Itch, From Transplanting Schwann Cells in Experimental Rat Spinal Cord Injury to their Transplantation into Human Injured Spinal Cord in Clinical Trials, and the Recruitment of Endogenous CNS Stem Cells for Regeneration in Demyelinating Disease. As the fourth in a periodic series of updates at 5-7 year intervals, this volume highlights recent developments in cellular and molecular science, providing the fundamental principles of neuroplasticity and regeneration in the brain and spinal cord, while also addressing the power of pluripotent stem cells to generate new sources of precisely specified neurons for utilization in brain repair.

  • Parkinson's Disease

    • 1 Edición
    • Volumen 132
    • Inglés
    Parkinson's Disease, Volume 132 addresses new developments in the F33 study of this disease, highlighting how the lives of people with Parkinson’s have undergone dramatic changes in the last decade. New to this edition are chapters on the Hallmarks of clinical aspects PD throughout centuries, The motor syndrome of Parkinson disease, The non-motor features of Parkinson’s disease, The New Diagnostic Criteria for Parkinson's disease, Advances in the Clinical Differential diagnosis, Clinical assessments in PD : Scales and monitoring, Biomarkers of Parkinson’s disease: an Introduction, and the Genetics of Parkinson’s Disease: Genotype-Phenotype Correlations. The topics discussed in this comprehensive series provide a clearer understanding of the prodromal stage, genetics, strategies, routes of treatment, and development of non-dopaminergic therapies in Parkinson's Disease, both medical and surgical.

  • Insect Immunity

    • 1 Edición
    • Volumen 52
    • Petros Ligoxygakis
    • Inglés
    Insect Immunity, Volume 52 provides readers with the latest interdisciplinary reviews on the topic. It is an essential reference source for invertebrate physiologists, neurobiologists, entomologists, zoologists and insect chemists, providing invaluable chapters on Insect Antimicrobial Defenses: A Brief History, Recent Findings, Biases, and a Way Forward in Evolutionary Studies, Phagocytosis in Insect Immunity, The Melanization Response in Insect Immunity, Microbiota, Gut Physiology, and Insect Immunity, Intestinal Stem Cells: A Decade of Intensive Research in Drosophila and the Road Ahead, and Insect Symbiosis and Immunity: The Bean Bug–Burkholderia Interaction as a Case Study, along with other related topics.

  • Functional Neural Transplantation IV

    Translation to Clinical Application, Part A
    • 1 Edición
    • Volumen 230
    • Inglés
    Functional Neural Transplantation IV: Translation to Clinical Application, Volume 230 provides the current status of cell transplantation in the nervous system, with a focus on the conditions for achieving structural repair and functional recovery after brain damage or in neurodegenerative disease. New to this release are chapters that delve into the Mechanisms and Use of Neural Transplants for Brain Repair, Reprogramming of Somatic Cells: iPS and iN Cells, Brain Repair from Intrinsic Cell Sources: Turning Reactive Glia into Neurons, and Ex Vivo Gene Therapy for the Treatment of Neurological Disorders, Preparation, Characterization and Banking of Clinical-grade Cells for Neural Transplantation. As the fourth in a periodic series of updates at 5-7 year intervals, this volume highlights recent developments related to the application of advances in cellular and molecular science, providing an understanding of the fundamental principles of neuroplasticity and regeneration in the brain and spinal cord, and also addressing the topic of the power of pluripotent stem cells to generate new sources of precisely specified neurons for utilization in brain repair.

  • Arteriovenous and Cavernous Malformations

    • 1 Edición
    • Volumen 143
    • Inglés
    Arteriovenous and Cavernous Malformations, Volume 143, is the latest addition in the ongoing HCN series, an evidence-based compendium which addresses both the scientific and clinical aspects of this unique disease process. The volume covers didactic aspects, such as the epidemiology, etiology, and diagnosis of AVMs, while also providing expert clinical information on the management and treatment of these lesions. In addition, it provides coverage of modern-day advances in the genetics of cavernous malformations, as well as discussion regarding future open research questions. Readers from the laboratory bench to the bedside can expect a broad, yet objective, review of this pathology, with updates from the latest scientific literature and data supporting current practices.

  • Neurochemical Aspects of Alzheimer's Disease

    Risk Factors, Pathogenesis, Biomarkers, and Potential Treatment Strategies
    • 1 Edición
    • Akhlaq A. Farooqui
    • Inglés
    Neurochemical Aspects of Alzheimer's Disease provides a comprehensive overview of molecular aspects of risk factors, pathogenesis, biomarkers, and therapeutic strategies. The book focuses on molecular mechanisms and signal transduction processes associated with the pathogenesis, biomarkers, and therapeutic strategies of AD. The comprehensive and cutting edge information in this monograph may not only help in early detection of AD, but also promote discovery of new drugs to treat this chronic disease. Chapters discuss involvement of neural membrane phospholipids, sphingolipids, and cholesterol-derived lipid mediators, abnormal APP processing, and nucleic acid damage, risk factors, biomarker, and therapeutic strategies of Alzheimer's disease. This book is written for neurologists, neuroscientists, neurochemists, neuropharmacologists... and clinicianswho are interested in molecular mechanisms associated with the pathogenesis of age-related neurological disorders.

  • Designing EEG Experiments for Studying the Brain

    Design Code and Example Datasets
    • 1 Edición
    • Aamir Saeed Malik + 1 más
    • Inglés
    Designing EEG Experiments for Studying the Brain: Design Code and Example Datasets details the design of various brain experiments using electroencephalogram (EEG). Providing guidelines for designing an EEG experiment, it is primarily for researchers who want to venture into this field by designing their own experiments as well as those who are excited about neuroscience and want to explore various applications related to the brain. The first chapter describes how to design an EEG experiment and details the various parameters that should be considered for success, while remaining chapters provide experiment design for a number of neurological applications, both clinical and behavioral. As each chapter is accompanied with experiment design codes and example datasets, those interested can quickly design their own experiments or use the current design for their own purposes. Helpful appendices provide various forms for one’s experiment including recruitment forms, feedback forms, ethics forms, and recommendations for related hardware equipment and software for data acquisition, processing, and analysis.

  • Understanding Food Systems

    Agriculture, Food Science, and Nutrition in the United States
    • 1 Edición
    • Ruth MacDonald + 1 más
    • Inglés
    Understanding Food Systems: Agriculture, Food Science, and Nutrition in the United States explores the complex and evolving system from which the United States gets its food. From farm, to home, and everything in-between, the authors use a scientific perspective that explains the fundamentals of agricultural production, food science, and human nutrition that will guide readers through the issues that shape our food system, including political, societal, environmental, economic, and ethical concerns. Presenting the role and impact of technology, from production to processing and safety, to cultural and consumer behavior perspectives, the book also explores the link between food systems and the history of nutrients and diet patterns, and how these influence disease occurrence. Current topics of concern and debate, including the correlations between food systems and diet-related diseases, such as obesity and diabetes are explored, as are the history and current status of food insecurity and accessibility. Throughout the text, readers are exposed to current topics that play important roles in personal food choices and how they influence components of the food system.

  • Nanoencapsulation of Food Bioactive Ingredients

    Principles and Applications
    • 1 Edición
    • Seid Mahdi Jafari
    • Inglés
    Nanoencapsulation of Food Bioactive Ingredients: Principles and Applications brings different nanoencapsulated food bioactive ingredients, their structure, applications, preparation, formulations and encapsulation methodologies, covering a wide range of compounds and giving detailed examples of the issues faced in their nano-encapsulation. The book addresses findings related to the study of natural food colorants, vitamins, antimicrobial agents, phenolic compounds, antioxidants, flavors, essential oils, fish oil and essential fatty acids, and other related ingredients. As a definitive manual for researchers and industry personnel working, or interested in, various branches of encapsulation for food ingredients and nutraceutical purposes, users will find this a great reference.

  • Neuroscience Basics

    A Guide to the Brain's Involvement in Everyday Activities
    • 1 Edición
    • Jennifer L. Larimore
    • Inglés
    Neuroscience Basics: A Guide to the Brain’s Involvement in Everyday Activities examines how our brain works in everyday activities like sleeping, eating, love, and exercise. Many want to better understand how the brain works, but the terminology and jargon of books can be overwhelming. The book covers the basics taught in an introductory neurobiology course designed for anyone new to the neuroscience field, including non-neuroscientists. While each of the chapters explore the brain in a normal state, Neuroscience Basics also discusses disruptions of the normal state—psychosis, Alzheimer’s, Parkinson’s, autism, learning disorders, etc. This book breaks down the topics into language that is more accessible while making the neuroscience topics fun and relevant.

  • A Text-Book of Medical Jurisprudence and Toxicology

    • 1 Edición
    • Rai Bahadur Jaising P. Modi
    • Inglés
    Medical Jurisprudence and Toxicology for India covers some essential details and practical aspects of medical jurisprudence and toxicology. This book is organized into two part encompassing 34 chapters. The opening chapters of Part I deal with legal procedure in criminal courts, physical evidence of the crime, autopsy, exhumation, and some medico-legal practices. Considerable chapters are devoted to other aspects of legal medicine, including determination of death causation, legitimacy of evidence, incident of rape and unnatural offenses, miscarriage, infanticide, insanity, and the privileges of medical men. Part II focuses on the toxicological aspects. This part emphasizes the medico-legal aspects of some classes of poisons, such as corrosive, irritant, neurotic, cerebral, spinal, cardiac, and peripheral poisons. This book will prove useful to medical college students.

  • Vegetarian and Plant-Based Diets in Health and Disease Prevention

    • 1 Edición
    • François Mariotti
    • Inglés
    Vegetarian and Plant-Based Diets in Health and Disease Prevention examines the science of vegetarian and plant-based diets and their nutritional impact on human health. This book assembles the science related to vegetarian and plant-based diets in a comprehensive, balanced, single reference that discusses both the overall benefits of plant-based diets on health and the risk of disease and issues concerning the status in certain nutrients of the individuals, while providing overall consideration to the entire spectrum of vegetarian diets. Broken into five sections, the first provides a general overview of vegetarian / plant-based diets so that readers have a foundational understanding of the topic. Dietary choices and their relation with nutritional transition and sustainability issues are discussed. The second and third sections provide a comprehensive description of the relationship between plant-based diets and health and disease prevention. The fourth section provides a deeper look into how the relationship between plant-based diets and health and disease prevention may differ in populations with different age or physiological status. The fifth and final section of the book details the nutrients and substances whose intakes are related to the proportions of plant or animal products in the diet.

  • Correlative Light and Electron Microscopy III

    • 1 Edición
    • Volumen 140
    • Inglés
    Correlative Light and Electron Microscopy III, Volume 140, a new volume in the Methods in Cell Biology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Topics discussed in this new release include Millisecond time-resolved CLEM, Super resolution LM und SEM of high-pressure frozen C. elegans, Preservation fluorescence, super res CLEM, APEX in Tissue, Corrsight mit IBIDI flowthrough chamber, Correlative Light Atomic Force Electronic Microscopy (CLAFEM), Atmospheric EM CLEM, and High-precision correlation, amongst other topics. Chapters in this ongoing series deal with different approaches for analyzing the same specimen using more than one imaging technique. The strengths and application area of each is presented, with this volume exploring the aspects of sample preparation of diverse biological systems for different CLEM approaches.

  • Mechanical Testing of Orthopaedic Implants

    • 1 Edición
    • Elizabeth Friis
    • Inglés
    Mechanical Testing of Orthopaedic Implants provides readers with a thorough overview of the fundamentals of orthopedic implants and various methods of mechanical testing. Historical aspects are presented, along with case studies that are particularly useful for readers.

  • Nanotechnology-Based Approaches for Targeting and Delivery of Drugs and Genes

    • 1 Edición
    • Vijay Mishra + 3 más
    • Inglés
    Nanotechnology-Based Approaches for Targeting and Delivery of Drugs and Genes provides an overview of the important aspects of nanomedicine in order to illustrate how to design and develop novel and effective drug delivery systems using nanotechnology. The book is organized into three sections, beginning with an introduction to nanomedicine and its associated issues. Section two discusses the latest technologies in nanomedicine, while the third section covers future developments and challenges in the field. By focusing on the design, synthesis, and application of a variety of nanocarriers in drug and gene delivery, this book provides pharmaceutical and materials science students, professors, clinical researchers, and industry scientists with a valuable resource aimed at tackling the challenges of delivering drugs and genes in a more targeted manner.

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