Saltar al contenido principal
Elsevier

Libros en Ciencias de la Vida

  • Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH)

    The Quintessential Moonlighting Protein in Normal Cell Function and in Human Disease
    • 1 Edición
    • Michael A. Sirover
    • Inglés
    Glyceraldehyde-3-Pho... Dehydrogenase (GAPDH): The Quintessential Moonlighting Protein in Normal Cell Function and in Human Disease examines the biochemical protein interactions of the multi-dimensional protein GAPDH, further considering the regulatory mechanisms through which cells control their functional diversity. This protein’s diverse activities range from nuclear tRNA export and the maintenance of genomic integrity, to cytoplasmic post-transcriptional control of gene expression and receptor mediated cell signaling, to membrane facilitation of iron metabolism, trafficking and fusion. This book will be of great interest to basic scientists, clinicians and students, including molecular and cell biologists, immunologists, pathologists and clinical researchers who are interested in the biochemistry of GAPDH in health and disease.

  • Functional Diversity of Mycorrhiza and Sustainable Agriculture

    Management to Overcome Biotic and Abiotic Stresses
    • 1 Edición
    • Michael J. Goss + 2 más
    • Inglés
    Functional Diversity of Mycorrhiza and Sustainable Agriculture is the first book to present the core concepts of working with Arbuscular mycorrhizal fungi to improve agricultural crop productivity. Highlighting the use of indigenous AM fungi for agriculture, the book includes details on how to maintain and promote AM fungal diversity to improve sustainability and cost-effectiveness. As the need to improve production while restricting scarce inputs and preventing environmental impacts increases, the use of AMF offers an important option for exploiting the soil microbial population. It can enhance nutrient cycling and minimize the impacts of biotic and abiotic stresses, such as soil-borne disease, drought, and metal toxicity. The book offers land managers, policymakers, soil scientists, and agronomists a novel approach to utilizing soil microbiology in improving agricultural practices.

  • Guide to Food Safety and Quality during Transportation

    Controls, Standards and Practices
    • 2 Edición
    • John M. Ryan
    • Inglés
    Guide to Food Safety and Quality during Transportation, Controls, Standards and Practice, Second Edition provides a solid foundation outlining logistics and delivery control solutions to protect the food transportation industry. Since its first publication, the U.S. FDA has finalized a number of Food Safety Modernization Act rules designed to improve the protection of the public from adulterants known to cause illness and death. Food shippers, carriers and receivers throughout the world are impacted as import controls have tightened. This book provides the information needed to comply with the Act’s requirements and tactics on how to achieve safety in the food supply chain. Filled with legal, liability and practical solutions, food transporters and buyers will be able to structure company-wide business practices as part of their overall food safety and quality agendas. For food safety and quality students, the book provides much needed insight into a critical, but overlooked, aspect of the food safety and food quality spectrums. This food transporter piece of the overall food safety and quality puzzle provides the linking mechanism needed to improve the supply chain communication and interdependence sought after by governmental and industry executives.

  • Ion Channels Down Under

    • 1 Edición
    • Volumen 79
    • Inglés
    Ion Channels Down Under, Volume 79 provides up-to-date information on ion channel pharmacology, their pharmacological modulators, and their role in a diverse range of poorly treated medical conditions. This new volume covers specific topics relating to Receptors and the Diversity in their Structure and Pharmacology, Acid-Sensing Ion Channel Pharmacology, Past, Present and Future, Sodium Channels and Venom Peptide Pharmacology, the Role of Non-Neuronal TRPV4 Signaling in Inflammatory Processes, and Genetically Encoded Calcium Indicators as Probes to Assess the Role of Calcium Channels in Disease and for High-Throughput Drug Discovery. Contributors in this series include prominent scientists and highly-recognized experts with major accomplishments in the field of ion channel pharmacology. Topics covered include the role of ion channels in health and disease, ion channels as therapeutic targets and the molecular pharmacology of ion channels.

  • Microbiology of Metal Ions

    • 1 Edición
    • Volumen 70
    • Inglés
    Advances in Microbial Physiology, Volume 70 continues the long tradition of topical, important, cutting-edge reviews in microbiology with this new volume covering a variety of topics, including Bacterial Hemoprotein Sensors of NO: H-NOX and NosP, Manganese in Marine Microbiology, Nutritional Immunity and Fungal Pathogenesis: The Struggle for Micronutrients at the Host-Pathogen Interface, Metal-Based Combinations that Target Protein Synthesis by Fungi, Transition Metal Homeostasis in Streptococcus Pyogenes and Streptococcus Pneumoniae, Copper and Antibiotics: Discovery, Modes of Action, and Opportunities for Medicinal Applications, Metal Resistance and Its Association with Antibiotic Resistance, and The Role of Intermetal Competition and Mis-Metalation in Metal Toxicity.

  • Hydronephrosis

    • 1 Edición
    • James C. Anderson
    • Inglés
    Hydronephrosis is a seven chapter text that brings together the technical and scientific advances that have improved the treatment of hydronephrosis. Hydronephrosis is the dilatation of the renal pelvis and calyces due to functional or mechanical disorder of the upper end of the ureter or the pelvis of the kidney. The introductory chapter provides an overview of the historical developments in the diagnosis and treatment options of hydronephrosis. The succeeding chapters discuss the disease's clinical manifestations, structural and functional aspects, symptoms, diagnosis, and operative procedures. The concluding chapters present various case histories on the results of surgical treatments of hydronephrotic patients. This book will be of value to urologists and kidney surgeons.

  • Physico-Chemical Aspects of Drug Action

    Proceedings of the Third International Pharmacological Meeting
    • 1 Edición
    • E. J. Ariëns
    • Inglés
    Physico-Chemical Aspects of Drug Action, Volume 7 covers topics on drug kinetics and the overall physicochemical properties of the drug in relation therewith, and the physicochemical aspects of the drug-receptor interaction, putting emphasis on receptor mechanisms and specific properties required for certain types of drugs in this respect. The book starts with some contributions dealing with various general aspects of drug kinetics followed by some contributions dealing with the relationship between certain physicochemical properties of drug molecules and their action. The text describes the pharmacokinetics and dose-concentration relationships; the time course of the biological response to drugs; and the empirical equations for correlating biological efficiency of organic compounds. The text also describes molecular basis for the action of chemotherapeutic drugs; the structure-activity studies on sulphonamides; and the water extrusion hypothesis. The mathematical treatment of two-point attachment between drug and receptor; the molecular properties and biological activity of catecholamines and certain related compounds; and the structure-activity relationships of diarylcarbinolethers are also considered. The book further tackles quantum mechanically-derived electronic distributions in the conformers of 2-pam; and the molecular basis for the action of certain drugs in the central nervous system. Pharmacologists and chemists will find the book invaluable.

  • Nuclear Receptors in Development and Disease

    • 1 Edición
    • Volumen 125
    • Inglés
    Nuclear Receptors in Development and Disease, Volume 125, the latest volume in the Current Topics in Developmental Biology series, covers nuclear receptors in development and disease, and includes contributions from an international board of authors. New chapters in this release cover the Evolution of Nuclear Receptors and Ligand Signaling: Towards a Soft Key–Lock Model?, The Function and Evolution of Nuclear Receptors in Insect Embryonic Development, Nuclear Receptors in Skeletal Homeostasis, Estrogen Hormone Biology, and the Mechanisms of Glucocorticoid Action During Development. The book's chapters provide a comprehensive set of reviews that cover such topics as nuclear differentiation and remodeling, evolution of receptors, ligand signaling and neural development.

  • Phytoremediation

    • 1 Edición
    • Volumen 83
    • Inglés
    Phytoremediation, Volume 83, the latest release in the Advances in Botanical Research series, covers a variety of new topics, including Metallophytes from calamine and serpentine soils (incl. tolerance mechanisms), The (endophytic) microbiome of plants from metal contaminated environments: small organisms (inhabitants), large influence, the Potential role of plant-associated bacteria in plant metal uptake and implications in phytotechnologies, Plant associated fungi from trace element rich soils and their possible role in metal uptake by their host plants, Phytoextraction: Status and Promise, Molecular and cellular aspects of contaminant toxicity in plants, and a section on Bio- and phytoremediation of pesticide-contaminat... environments: a Review. This series publishes in-depth and up-to-date reviews on a wide range of topics in the plant sciences, featuring reviews by recognized experts on all aspects of plant genetics, biochemistry, cell biology, molecular biology, physiology and ecology.

  • The Technology of Wafers and Waffles I

    Operational Aspects
    • 1 Edición
    • Karl F. Tiefenbacher
    • Inglés
    The Technology of Wafers and Waffles: Operational Aspects is the definitive reference book on wafer and waffle technology and manufacture. It covers specific ingredient technology (including water quality, wheat flour, starches, dextrins, oils and fats) and delves extensively into the manufacturing elements and technological themes in wafer manufacturing, including no/low sugar wafers, hygroscopic wafers, fillings and enrobing. The book explains, in detail, operating procedures such as mixing, baking, filling, cooling, cutting and packaging for every type of wafer: flat and shaped wafers for making biscuits, ice cream cones, cups, wafer reels, wafer sticks (flute wafers) and biscuit wafers. It also explores the various types of European (Belgian) waffles and North American frozen waffles.

  • International Review of Cell and Molecular Biology

    • 1 Edición
    • Volumen 332
    • Inglés
    International Review of Cell and Molecular Biology, Volume 332 reviews current advances in cell and molecular biology. This latest release covers Metabolic alterations at the crossroad between aging and oncogenesis, Molecular and cellular mechanisms of auto-immunity, Old and novel functions of caspase-2, Organelle crosstalk in oncogenic metabolic reprogramming, a Molecular Biology Digest of Cellular Mitophagy, the Regulation of cell calcium and role of plasma membrane calcium ATPases, and Mechanisms of cortical differentiation. The IRCMB series has a worldwide readership, maintaining a high standard by publishing invited articles on important and timely topics that are authored by prominent cell and molecular biologists. Users will find that the articles published in IRCMB have a high impact and average cited half-life of nine years. This great resource ranks high amongst scientific journals dealing with cell biology.

  • Principles of Gender-Specific Medicine

    Gender in the Genomic Era
    • 3 Edición
    • Marianne Legato J
    • Inglés
    The announcement that we had decoded the human genome in 2000 ushered in a new and unique era in biomedical research and clinical medicine. This Third Edition of Principles of Gender-Specific Medicine focuses, as in the past two editions, on the essentials of sexual dimorphism in human physiology and pathophysiology, but emphasizes the latest information about molecular biology and genomic science in a variety of disciplines. Thus, this edition is a departure from the previous two; the editor solicited individual manuscripts from innovative scientists in a variety of fields rather than the traditional arrangement of sections devoted to the various subspecialties of medicine edited by section chiefs. Wherever it was available, these authors incorporated the latest information about the impact of the genome and the elements that modify its expression on human physiology and illness. All chapters progress translationally from basic science to the clinical applications of gender-specific therapy and suggest the most important topics for future investigation. This book is essential reading for all biomedical investigators and medical educators involved in gender-specific medicine. It will also be useful for primary care practitioners who need information about the importance of sex and gender in the prevention, diagnosis and treatment of illness. Winner of the 2018 PROSE Award in Clinical Medicine from the Association of American Publishers!

  • Advances in Agronomy

    • 1 Edición
    • Volumen 144
    • Inglés
    Advances in Agronomy, Volume 144, the newest release in a serial that continues to be recognized as a leading reference and first-rate source for the latest research in agronomy presents new information on the following topics: An Important Tool with No Instruction Manual: A Review of Gypsum Use in Agriculture, Preventive Weed Management in Direct-Seeded Rice: Targeting the Weed Seedbank, Current Approaches and Future Trends in Compost Quality Criteria for Agronomic, Environmental and Human Health Benefits, and Grain Legume Production and Use in European Agricultural Systems. This highly regarded series contains an eclectic group of reviews by leading scientists throughout the world. As always, the subjects covered are rich, varied and comprehensively covered.

  • The End of Alzheimer’s

    The Brain and Beyond
    • 2 Edición
    • Thomas J. Lewis + 1 más
    • Inglés
    The End of Alzheimer’s: The Brain and Beyond, Second Edition is the first comprehensive overview on the molecular basis of Alzheimer’s outside of the brain, merging the most recent findings within the field into a single book. It aims to educate the reader on the many overlooked aspects of Alzheimer’s disease that occur outside the brain. This book uniquely provides step-by-step, peer-reviewed evidence that the current research model may be misguided and that a new and emerging model is more accurate. It carefully outlines the molecular research in Alzheimer’s outside the brain and argues that a more thorough, whole-body diagnosis will provide better answers about its causes and lead to new treatments. It is beneficial to researchers who need to be apprised of the emerging science on the causes of Alzheimer’s, and will hopefully redirect many into new avenues of cellular research and discovery.

  • Biology of Oysters

    • 1 Edición
    • Volumen 41
    • Brian Leicester Bayne
    • Inglés
    Biology of Oysters offers scientific insights into the structure and function of oysters. Written by an expert in the field of shellfish research, this book presents more than 50 years of empirical research literature. It provides an understanding of the edible oysters, in order to equip students and researchers with the background needed to undertake further investigations on this model marine invertebrate.

  • The Endocannabinoid System

    Genetics, Biochemistry, Brain Disorders, and Therapy
    • 1 Edición
    • Eric Murillo-Rodriguez
    • Inglés
    The Endocannabinoid System: Genetics, Biochemistry, Brain Disorders, and Therapy examines the cellular, biochemical, genetic, and therapeutic aspects of the endocannabinoid system. The chapters cover significant conceptual advances in the endocannabinoid field and shed light on the many brain disorders in which this biological system is involved. Written by world-leading experts in the field, the topics covered in this book will have a positive impact on the area of molecular biology, including, but not limited to, cell biology, neuroscience, pharmacology, signaling, disease mechanisms, and therapeutics.

  • Cheese

    Chemistry, Physics and Microbiology
    • 4 Edición
    • Paul L.H. McSweeney + 2 más
    • Inglés
    Cheese: Chemistry, Physics and Microbiology, Fourth Edition, provides a comprehensive overview of the chemical, biochemical, microbiological, and physico-chemical aspects of cheese, taking the reader from rennet and acid coagulation of milk, to the role of cheese and related foods in addressing public health issues. The work addresses the science from the basic definition of cheese, to the diverse factors that affect the quality of cheese. Understanding these fermented milk-based food products is vital to a global audience, with the market for cheese continuing to increase even as new nutritional options are explored. Additional focus is provided on the specific aspects of the ten major variety cheese families as defined by the characteristic features of their ripening. The book provides over 1000 varieties of this globally popular food.

  • Gastrointestinal Tissue

    Oxidative Stress and Dietary Antioxidants
    • 1 Edición
    • Jordi Gracia-Sancho + 1 más
    • Inglés
    Gastrointestinal Tissue: Oxidative Stress and Dietary Antioxidants brings together leading experts from world renowned institutions, combining the basic mechanisms of gastrointestinal diseases with information regarding new and alternative treatments. The processes within the science of oxidative stress are described in concert with other processes, including apoptosis, cell signaling and receptor mediated responses, further recognizing that diseases are often multifactorial with oxidative stress as a component. By combining the critical molecular processes underlying free radical mediated pathologies and the role of dietary antioxidant molecules, a connection is made that helps advance therapies and the prevention of gastrointestinal pathological processes. This important reference is well designed with two complementary sections. Section One, Oxidative Stress and Gastroenterology, covers the basic processes of oxidative stress from molecular biology to whole organs, the gastrointestinal anatomy and sources of oxidative stress and free radicals and their products in gastrointestinal diseases. Section Two, Antioxidants and Gastroenterology covers antioxidants in foods, including plants and components.

  • A Primer in Financial Data Management

    • 1 Edición
    • Martijn Groot
    • Inglés
    A Primer in Financial Data Management describes concepts and methods, considering financial data management, not as a technological challenge, but as a key asset that underpins effective business management. This broad survey of data management in financial services discusses the data and process needs from the business user, client and regulatory perspectives. Its non-technical descriptions and insights can be used by readers with diverse interests across the financial services industry. The need has never been greater for skills, systems, and methodologies to manage information in financial markets. The volume of data, the diversity of sources, and the power of the tools to process it massively increased. Demands from business, customers, and regulators on transparency, safety, and above all, timely availability of high quality information for decision-making and reporting have grown in tandem, making this book a must read for those working in, or interested in, financial management.

  • Adverse Events and Oncotargeted Kinase Inhibitors

    • 1 Edición
    • Giuseppe Tridente
    • Inglés
    Adverse Events and Oncotargeted Kinase Inhibitors gathers and evaluates data on adverse events associated with tyrosine kinase inhibitors (TKIs), a powerful anti-tumor drug class that has recently been introduced for human therapy. This book compiles a comprehensive safety profile of each TKI from experiences in official therapeutic indications, also exploring off-label exploratory investigations and postmarketing pharmaceutical surveillance databases. A brief history of each drug’s development and submission is provided, along with a more detailed analysis of the mechanism(s) of action involved in therapeutic activity or related to the insurgence of specific adverse events. Early chapters focus on general characteristics of TKIs, typology, and classification of adverse events, while the final chapters analyze TKIs as AE inducers and classes of AEs by system or organ involvement. This comprehensive resource compiles and critically reviews all of the relevant safety data for this class of drugs, with the goal of improving the understanding of pathogenesis and facilitating the prevention, monitoring, and management of these adverse events.

  • Handbook of Coffee Processing By-Products

    Sustainable Applications
    • 1 Edición
    • Charis M. Galanakis
    • Inglés
    Handbook of Coffee Processing By-Products: Sustainable Applications presents alternative and sustainable solutions for coffee processing by-products and specifies their industrial potential, both as a source for the recovery of bioactive compounds and their reutilization in the pharmaceutical, biotechnological, food, biotechnology, and cosmetic industries, also covering environmental and agronomic applications. This book addresses key topics specific to sustainable management in the coffee industry, placing an emphasis on integrated solutions for the valorization and upgrade of coffee processing by-products, biorefinery, and different techniques for the separation, extraction, recovery and formulation of polyphenols.

  • Principles and Measurements in Environmental Biology

    • 1 Edición
    • F I Woodward + 1 más
    • Inglés
    Principles and Measurements in Environmental Biology aims to provide an understanding of some important physical principles and their application in biology. The book also aims to describe how instruments utilizing these principles can be used to measure biological and environmental processes and their interactions. This book covers the effects of the environment on biological organisms; the application of theories of radiation, kinetic theory, gas laws, and diffusion in biology; and water and its properties. The relation of plants with atmosphere near the ground is also discussed. This book also presents sampling techniques; the computation of errors used in the interpretation of data; the use of different devices; and data gathering and its practical applications. This text is for students, researchers, and professionals and experts in biology who wish to understand the mentioned principles in physics, its mathematical aspects, and their applications in the field.

  • T–cell Activation in Health and Disease

    Disorders of Immune Regulation Infection and Autoimmunity: Papers from an International Meeting in Oxford, UK, in September 1988
    • 1 Edición
    • M Feldmann + 2 más
    • Inglés
    T-cell Activation in Health and Disease is a collection of papers presented at the "T-cell Activation in Health and Disease—Disorders of Immune Regulation—Infection and Autoimmunity" workshop held in Oxford on September 25-29, 1988. This book discusses the progress occurring in T-cell immunity research. One paper discusses the effects of two interaction clones of T-cells that can define the T-cell immunoregulatory network. Another paper discusses the relationship between connectivity and tolerance of the immune network. This paper then suggests the possibility that autoimmunity arises because self-reactive clones are inadequately connected to the network. Another paper reviews the cell-mediated responses in the synovial fluids, as well as the interaction of rheumatoid arthritis synovial fluid dendritic cells and T lymphocytes. The book also examines why attempts for protective immunity to the HIV virus have not been successful. One article then discusses the goals of immunologic intervention in autoimmune disease by using an approach involving the cellular and cytokine targets and their deployment. This text can prove significant for scientists in the field of pharmacology, cellular biology, and researchers in the field of immunology and infectious diseases.

  • Atherosclerotic Plaque Characterization Methods Based on Coronary Imaging

    • 1 Edición
    • Lambros S Athanasiou + 2 más
    • Inglés
    Atherosclerotic Plaque Characterization Methods Based on Coronary Imaging provides a complete review of computer methods for atherosclerotic plaque reconstruction and characterization. The authors, with their expertise from biomedical engineering, computer science, and cardiology, offer a holistic view. The focus of the book is on the presentation of major imaging techniques, including their limitations. It includes details on the mechanical characterization and properties of plaques and appropriate constitutive models to describe the mechanical behavior of plaques. The authors explore the challenges of using multiple coronary imaging technologies, and provide the pros and cons of invasive vs. non-invasive techniques. Methods for plaque characterization and 3D reconstruction of coronary arteries using IVUS, OCT, and CT images are described. This book will help readers study new trends in image processing analysis and plaque characterization, implement automated plaque characterization methodologies, understand coronary imaging drawbacks, and comprehend 3 dimensional coronary artery and plaque reconstruction methods.

  • Growth in Animals

    Studies in the Agricultural and Food Sciences
    • 1 Edición
    • T.L.J. Lawrence
    • Inglés
    Studies in the Agricultural and Food Sciences: Growth in Animals discusses the more advanced concepts of growth, its changes and effects on different animals and systems, and its implications for agriculture. Based on a symposium of the same name, the book defines growth and its effects on the whole body; the biochemical and genetic determinants that affect it; and the effect of thermal environment on growth and its relation with immunity. Growth of bones, muscle nucleic acid and protein, and adipose tissue are also explained. The text also encompasses the relation of growth and gut microflora; the effects of growth-promoting agents in ruminant animals and single-stomach animals; and growth and breeding performance in animals. The growth in mammals and birds for meat production and its effects on the meat quality of animals are also covered in this book. This monograph is recommended for those who would want to start or are currently running animal and poultry farms, as well as for scientists who wish to study the phenomenon of growth for the betterment of agriculture.

  • The Ultrastructure of the Animal Cell

    International Series in Pure and Applied Biology
    • 2 Edición
    • L. T. Threadgold
    • G. A. Kerkut
    • Inglés
    The Ultrastructure of the Animal Cell examines the ultrastructure of the animal cell, with emphasis on the chemical, biochemical, and physiological aspects of the cell. Discussions are organized around the interphase cell and cell division and cover topics ranging from the general structure and molecular models of cell membranes to the ultrastructure of the nucleus and the cytosome. Changes in cell ultrastructure during embryogenesis, differentiation, and secretion are also considered. This monograph is divided into nine chapters and opens with an introduction to the principles and techniques of electron microscopy. The next section is about the interphase cell and first presents an overview of the animal cell before proceeding with an analysis of the ultrastructure of the nucleus and the cytosome, paying particular attention to the plasma membrane and associated structures; the hyaloplasm; endoplasmic reticulum; the Golgi complex; and mitochondria. The changes that occur in the ultrastructure of the cell during embryogenesis, differentiation, and secretion are also described. The last section focuses on cell division and the ultrastructure of the dividing cell. This text will be a useful resource for cell biologists, biochemists, and physiologists, as well as students and teachers of biology, biochemistry, and physiology.

  • Control of Growth and Metamorphosis

    Animal Hormones: A Comparative Survey
    • 1 Edición
    • Penelope M. Jenkin
    • G. A. Kerkut
    • Inglés
    International Series of Monographs in Pure and Applied Biology: Zoology Division, Volume 47: Control of Growth and Metamorphosis details the differences in animal hormones. The title focuses on covering morphogenetic hormones. The selection first defines and classifies morphogenetic hormones, and then proceeds to detailing the sources of hormones related to morphogenesis. Next, the selection tackles growth and mitosis, along with molting and metamorphosis. The last chapter deals with the control of morphogenetic hormones. The book will be of great use to students, researchers, and practitioners of zoology.

  • Problems of the Agricultural Development of Less-Favoured Areas in Europe

    Proceedings of a Symposium of the Committee on Agricultural Problems Economic Commission for Europe and Food and Agriculture Organization, Geneva, Switzerland, 22-26 May 1978
    • 1 Edición
    • Sam Stuart
    • Inglés
    Problems of the Agricultural Development of Less-Favoured Areas in Europe is a collection of papers from a symposium of the United Nations Economic Commission for Europe and Food and Agriculture Organization held in Geneva on May 22-26, 1978. This collection of papers covers European countries with areas where agricultural development is limited. This book defines less-favored agricultural areas as those places where there is limited agricultural development, of different sizes and economic and social importance. These areas are also defined as suffering serious deterioration of the natural environment and of economic and social activities. This book then presents country reports covering problem areas in Austria, Belgium, Czechoslovakia, Finland, France, and Germany. In reviewing each of these countries, and other countries as well, the text presents each government's objectives concerning the rural areas, the actual strategies and policies pursued by the state, and the problems encountered when implementing these policies. This text also gives the methodologies used in evaluating these programs. This book can prove useful for government officials and ministries dealing with the agricultural sector, heads of volunteer organizations dealing with countryside development, and academicians in political science and developmental planning.

  • Alkaloids: Chemical and Biological Perspectives

    • 1 Edición
    • Volumen 9
    • S.W. Pelletier
    • Inglés
    This monograph series provides unprecedented interdisciplinary coverage of research relating to the chemistry and biological properties of alkaloids - a class of biologically active compounds of more than 10,000 members. Timely, comprehensive and authoritative, the series features chapters on chemical properties and structure elucidation, synthesis, biosynthesis, taxonomy, spectroscopy, pharmacology, toxicology, and X-ray crystallography of alkaloids. The chapters are written and reviewed by eminent researchers, all of them acknowledged experts in the field. Subject and organism indexes are included for each volume.

  • Biological Monitoring in Water Pollution

    • 1 Edición
    • John E. Cairns
    • Inglés
    Biological Monitoring in Water Pollution focuses on the processes, methodologies, and experiments involved in monitoring water pollution. Divided into six parts, the selection features the contributions of authors who have devoted time and energy in advancing biological monitoring to measure pollution in water. The first part is a review paper that focuses on the strengths of biological monitoring relative to the detection of harmful conditions. This part stresses that biological monitoring has received considerable attention. The second part deals with review papers on biological monitoring. The discussions focused on the identification of problem; the review of functional methods; community and ecosystem indices used in biomonitoring; and structure and function relationships relative to ecosystem stress. The third part covers the application of community structural analysis to biomonitoring programs. This part puts emphasis on the need to develop methods to identify community structures relative to the conduct of ecological research. Other parts of the selection are devoted to toxicity testing and discussions on the monitoring of waste discharges and introduction of chemicals to the environment. Experiments and models are presented to support the claims of the authors. The book can be a valuable source of information for those interested in the monitoring of water pollution.

  • Multifunctional Systems for Combined Delivery, Biosensing and Diagnostics

    • 1 Edición
    • Alexandru Mihai Grumezescu
    • Inglés
    Multifunctional Systems for Combined Delivery, Biosensing, and Diagnostics explores how multifunctional nanocarriers are being used in combined delivery and diagnostics in contemporary medicine. Particular attention is given to efforts to i) reduce the side effects of therapeutic agents, ii) increase the pharmacological effect, and iii) improve aqueous solubility and chemical stability of different therapeutic agents. The chapters focus on applications of nanostructured materials and nanocarriers, highlighting how these can be used effectively in both diagnosis and delivery. This applied focus makes the book an important reference source for those wanting to learn more about how specific nanomaterials and nanotechnology systems can help to solve drug delivery and diagnostics problems. This book is a valuable resource for materials scientists, bioengineers, and medical researchers who are looking for an applications-oriente... guide on how nanotechnology and nanomaterials can be used effectively throughout the medical treatment process, from diagnosis to treatment.

  • Essentials of Chinese Materia Medica and Medical Formulas

    New Century Traditional Chinese Medicine
    • 1 Edición
    • Shengyan Xi + 1 más
    • Inglés
    Essentials of Chinese Materia Medica and Medical Formulas: New Century Traditional Chinese Medicine presents specific knowledge about the source, medicinal nature, action and application of more than 800 commonly-used Chinese materia medica, as well as the efficacy and application of more than 740 kinds of commonly-used Chinese medical formulas. Notably, all of the content is presented in table form, making the information easier to access, understand and apply. Each primary herbal medicine is introduced with color pictures, and each primary formula is presented with efficacy analysis pictures. The book provides readers with essential information on Chinese materia medica and formulas and how to use them accurately, including the most common Chinese materia medica used in clinics and in commonly used clinical formulas. This is an essential reference for traditional medical professionals and those interested in traditional Chinese medicine, including advanced undergraduate and postgraduate students.

  • Lawrie's Meat Science

    • 8 Edición
    • Fidel Toldra
    • Inglés
    Lawrie’s Meat Science, Eighth Edition, provides a timely and thorough update to this key reference work, documenting significant advances in the meat industry, including storage and preservation of meat, the eating quality of meat, and meat safety. The book examines the growth and development of meat animals, from the conversion of muscle to meat and eventual point of consumption. This updated volume has been expanded to include chapters examining such areas as packaging and storage, meat tenderness, and meat safety. Furthermore, central issues such as the effects of meat on health and the nutritional value of meat are analyzed. Broadly split into four sections, the book opens with the fundamentals behind the growth of meat animals. The second section covers the storage and spoilage of meat products, with the third section exploring the eating quality of meat, from flavor to color. The final section reviews meat safety, authenticity, and the effect of meat on health.

  • Blanco's Overview of Alpha-1 Antitrypsin Deficiency

    History, Biology, Pathophysiology, Related Diseases, Diagnosis and Treatment
    • 1 Edición
    • Ignacio Blanco
    • Inglés
    Blanco’s Overview of Alpha-1 Antitrypsin Deficiency: History, Biology, Pathophysiology, Related Diseases, Diagnosis, and Treatment is a robust introduction to topics associated with Alpha-1 Antitrypsin Deficiency (AATD). Included are topics ranging from the history of the disease, biology, pathophysiology, related diseases, including the two major manifestations of the disease (liver disease and lung disease), and diagnosis and treatment. The book addresses the need for the amalgamation of current and novel concepts and practices in the field of AATD. AATD is under-recognized in the medical community and, as a result, it is underdiagnosed. The book provides increased awareness and understanding of the condition to improve diagnosis rates and enhance patient care. This book is an essential tool and reference, beneficial to clinicians who screen and treat AATD patients, as well as research scientists working in the AATD field at junior and senior levels.

  • Nutrition in the Prevention and Treatment of Disease

    • 4 Edición
    • Ann M. Coulston + 3 más
    • Inglés
    Nutrition in the Prevention and Treatment of Disease, Fourth Edition, is a compilation of current knowledge in clinical nutrition and an overview of the rationale and science base of its application to practice in the prevention and treatment of disease. In its fourth edition, this text continues the tradition of incorporating new discoveries and methods related to this important area of research Generating and analyzing data that summarize dietary intake and its association with disease are valuable tasks in treating disease and developing disease prevention strategies. Well-founded medical nutrition therapies can minimize disease development and related complications. Providing scientifically sound, creative, and effective nutrition interventions is both challenging and rewarding.

  • Biometals in Neurodegenerative Diseases

    Mechanisms and Therapeutics
    • 1 Edición
    • Anthony R. White + 3 más
    • Inglés
    Biometals in Neurodegenerative Diseases: Mechanisms and Therapeutics is an authoritative and timely resource bringing together the major findings in the field for ease of access to those working in the field or with an interest in metals and their role in brain function, disease, and as therapeutic targets. Chapters cover metals in Alzheimer’s Disease, Parkinson’s Disease, Motor Neuron Disease, Autism and lysosomal storage disorders. This book is written for academic researchers, clinicians and advanced graduate students studying or treating patients in neurodegeneration, neurochemistry, neurology and neurotoxicology. The scientific literature in this field is advancing rapidly, with approximately 300 publications per year adding to our knowledge of how biometals contribute to neurodegenerative diseases. Despite this rapid increase in our understanding of biometals in brain disease, the fields of biomedicine and neuroscience have often overlooked this information. The need to bring the research on biometals in neurodegeneration to the forefront of biomedical research is essential in order to understand neurodegenerative disease processes and develop effective therapeutics.

  • Lepidoptera Genetics

    International Series of Monographs in Pure and Applied Biology: Zoology
    • 1 Edición
    • Roy Robinson
    • G. A. Kerkut
    • Inglés
    Lepidoptera Genetics provides a systematic account of the genetics and karyology of Lepidoptera. Topics covered include the use of biometry in genetic studies; population genetics and polymorphism; the rise of industrial melanism; and the evolution of mimicry. The genetics of Rhopalocera and Heterocera is also discussed. This book is comprised of eight chapters and begins with an overview of Lepidoptera species and their genetics, paying particular attention to color and pigmentation, breeding, and resistance to insecticides, as well as the effect of seasonal variations and the environment on Lepidoptera. The next chapter outlines the tenets of genetics that are of value for Lepidoptera research, including particulate heredity, random assortment, sex-linked inheritance, maternal inheritance, and mosaicism. The reader is methodically introduced to the application of biometry to the study of Lepidoptera genetics; the evolution of mimicry in Lepidoptera; and the known heredity of Rhopalocera and Heterocera. The final chapter examines the karyology of Lepidoptera, focusing on the haploid karyotype, polyploidy, chiasmata frequency, supernumerary chromosomes, and sex chromatin. This monograph will be a useful resource for entomologists, geneticists, and biologists.

  • The Pilchard

    Biology and Exploitation
    • 1 Edición
    • Michael Culley
    • G. A. Kerkut
    • Inglés
    The Pilchard: Biology and Exploitation discusses various concerns in the global pilchard industry. The book is comprised of 23 chapters that are organized into five parts. The text first introduces the biology of pilchard, its geographical distribution, and its zoological classification. Parts II to IV tackle the various issues in pilchard industries in different regions, namely, England, California, South Africa, and West Africa. The coverage of the book includes catching, processing, demand, and profitability. The book will be of great use to individuals involved in the pilchard industries. Researchers of fisheries science will also benefit from the book.

  • Mixed-Species Groups of Animals

    Behavior, Community Structure, and Conservation
    • 1 Edición
    • Eben Goodale + 2 más
    • Inglés
    Mixed-Species Groups of Animals: Behavior, Community Structure, and Conservation presents a comprehensive discussion on the mixed-species groups of animals, a spectacular and accessible example of the complexity of species interactions. They are found in a wide range of animals, including invertebrates, fish, mammals and birds, and in different habitats, both terrestrial and aquatic, throughout the world. While there are more than 500 articles on this subject scattered in separate categories of journals, there has yet to be a general, cross-taxa book-length introduction to this subject that summarizes the behavior and community structure of these groups. The authors first survey the diversity of spatial associations among animals and then concentrate on moving groups. They review the major classes of theories that have been developed to explain their presence, particularly in how groups increase foraging efficiency and decrease predation. Finally, they explore the intricacies of species interactions, such as communication, that explain species roles in groups and discuss what implications these social systems have for conservation.

  • Epigenetics and Systems Biology

    • 1 Edición
    • Leonie Ringrose
    • Inglés
    Epigenetics and Systems Biology highlights the need for collaboration between experiments and theoretical modeling that is required for successful application of systems biology in epigenetics studies. This book breaks down the obstacles which exist between systems biology and epigenetics researchers due to information barriers and segmented research, giving real-life examples of successful combinations of systems biology and epigenetics experiments. Each section covers one type of modeling and one set of epigenetic questions on which said models have been successfully applied. In addition, the book highlights how modeling and systems biology relate to studies of RNA, DNA, and genome instability, mechanisms of DNA damage signaling and repair, and the effect of the environment on genome stability.

  • The Microbiology of Skin, Soft Tissue, Bone and Joint Infections

    • 1 Edición
    • Volumen 2
    • Kateryna Kon + 1 más
    • Inglés
    The Microbiology of Skin, Soft Tissue, Bone and Joint Infections: Volume 2 discusses modern approaches in diagnosis, treatment, and prophylaxis of skin, soft tissue, bone, and joint infections. The volume has been divided into three sections. The first section includes chapters on diagnosis, treatment, and prophylaxis of skin and soft tissue infections. It discusses antimicrobial and surgical treatment of wounds, diabetic foot, and different soft tissue infections. Ten chapters are devoted to cutaneous and musculoskeletal infections in special groups of patients, which have their own specificity, i.e. in pediatric and HIV-infected patients. Together with chapters on commonly present diseases, there are chapters which discuss interesting but not well studied pathologies (natal cleft pilonidal sinus) and pathogens (Malassezia and Shewanella spp.). The second section reviews etiology, pathogenesis, diagnosis and treatment of bone and joint infections, mainly osteomyelitis and prosthetic joint infections. Also, one chapter in this section discusses a newly emerging bacterial pathogen that causes skeletal infections, Kingella kingae. The third section incorporates alternative and new approaches—such as nanotechnology, ultrasound, novel delivery approaches and phyto-derived medicines—to the treatment and prophylaxis of skin, soft tissue, bone, and joint infections.

  • Early Warning for Infectious Disease Outbreak

    Theory and Practice
    • 1 Edición
    • Weizhong Yang
    • Inglés
    Early Warning for Infectious Disease Outbreak: Theory and Practice is divided into three parts, with the first section introducing basic theory and key technologies of early warning and the basic principles of infectious disease surveillance. The second section introduces the technical details in the process of establishment, operation and usage of CIDARS and Pudong Syndromic Surveillance and the Early Warning System of the Shanghai World Expo. The third part explores the study of early warning technology, collecting some useful exploration in the fields of infectious diseases involving sentinel setting, data analysis, influence factors study, calculation and evaluation of early warning models.

  • Arthropod Vector: Controller of Disease Transmission, Volume 1

    Vector Microbiome and Innate Immunity of Arthropods
    • 1 Edición
    • Stephen K. Wikel + 2 más
    • Inglés
    Arthropod Vector: Controller of Disease Transmission, Volume 1: Vector Microbiome and Innate Immunity of Arthropods is built on topics initially raised at a related Keystone Symposium on Arthropod Vectors. Together with the separate, related Volume 2: Vector Saliva-Host Pathogen Interactions, this work presents a logical sequence of topic development that leads to regulatory considerations for advancing these and related concepts for developing novel control measures. The three themes of symbionts, vector immune defenses and arthropod saliva modulation of the host environment are central to the concept of determinants of vector competence that involves all aspects of vector-borne pathogen development within the arthropod that culminates in the successful transmission to the vertebrate host. These three areas are characterized at the present time by rapid achievement of significant, incremental insights, which advances our understanding for a wide variety of arthropod vector species, and this work is the first to extensively integrate these themes.

  • A Roadmap for Curing Cancer, Alzheimer's, and Cardiovascular Disease

    • 1 Edición
    • Paul J. Marangos
    • Inglés
    Cancer, dementia, and cardiovascular disease are responsible for almost two million deaths each year in the United States alone and represent the largest immediate threat to humanity. Over the last century, we have made spectacular advances that have transformed our society – splitting the atom, space travel, telecommunications, and the Internet – but with medical research focused mostly on science for the sake of science, it has yielded precious few cures. A Roadmap for Curing Cancer, Alzheimer’s, and Cardiovascular Disease represents a "first of its kind" effort to address both the reasons for this and to posit solutions to fix our broken system, in an effort to finally end this cure crisis. Dr. Marangos draws on 45 years of experience in every aspect of the biomedical R&D field, from basic drug discovery research at the NIH to the co-founding of five drug companies. He has published 252 research papers and edited four books on drug discovery, is co-inventor on 14 patents, and founded "The Journal of Molecular Neuroscience". He argues that from a development perspective, the regulatory, patent, and legal hurdles that force industry to pursue so-called "me-too" drugs rather than cures for terminal diseases must be re-thought. Leadership accountability, strategy, focus, and urgency need to be re-evaluated, and major reforms to the NIH, FDA, and patent codes are proposed.to remedy these impediments to cures. Written for anyone frustrated with the seemingly endless threat of terminal disease, this book seeks to inform, energize, and provide the rationale for the public and industry stakeholders, as well as clinicians and researchers, to resurrect the physician-patient relationship and demand that we get serious about ridding society of this scourge on humanity. This work contains the views and opinions of the author and are in no way intended to harm the reputation of any person, agency, organization, or commercial entity discussed herein. www.cureterminaldise...

  • Arthropod Vector: Controller of Disease Transmission, Volume 2

    Vector Saliva-Host-Pathogen Interactions
    • 1 Edición
    • Stephen K. Wikel + 2 más
    • Inglés
    Arthropod Vector: Controller of Disease Transmission, Volume 2: Vector Saliva-Host Pathogen Interactions is built on topics initially raised at a related Keystone Symposium on Arthropod Vectors. Together with the separate, related Volume 1: Controller of Disease Transmission, this work presents a logical sequence of topic development that leads to regulatory considerations for advancing these and related concepts for developing novel control measures. The three themes of symbionts, vector immune defenses and arthropod saliva modulation of the host environment are central to the concept of determinants of vector competence that involves all aspects of vector-borne pathogen development within the arthropod that culminates in the successful transmission to the vertebrate host. These three areas are characterized at the present time by rapid achievement of significant, incremental insights, which advances our understanding for a wide variety of arthropod vector species, and this work is the first to extensively integrate these themes.

  • Advances in Applied Microbiology

    • 1 Edición
    • Volumen 99
    • Inglés
    Advances in Applied Microbiology, Volume 99 continues is one of the most widely read and authoritative review sources in microbiology, containing comprehensive reviews of the most current research in applied microbiology. This volume presents comprehensive information on a variety of topics, including the Physiological Role of Two-Component Signal Transduction Systems in Food-Associated Lactic Acid Bacteria, Fungal Bio recovery of Gold from E-Waste, Stone-Eating Fungi: Mechanisms in Bio weathering and the Potential Role of Laccases in Black Slate Degradation with the Basidiomycete Schizophyllum commune, and the Arsenic Detoxification System in Corynebacteria: Basis and Application for Bioremediation and Redox Control. This serial's eclectic volumes are supplemented by thematic volumes on various topics, including Archaea and sick building syndrome. Users will find invaluable references and information on a variety of areas, including protozoan grazing of freshwater biofilms, metals in yeast fermentation processes, the interpretation of host-pathogen dialogue through microarrays, and the role of polyamines in bacterial growth and biofilm formation.

  • Brain-Based Learning and Education

    Principles and Practice
    • 1 Edición
    • Yi-Yuan Tang
    • Inglés
    Brain-Based Learning and Education presents a new type of education that uses brain-based and self-control theory-driven training. Leaving aside the current focus in education on content knowledge, it examines essential character strengths such as selfcontrol, persistence, creativity, attention, memory, and social learning, and relates their relevance to learning. By bridging the research and application gap in education, this text not only covers the latest findings related to learning and teaching but also provides insights for application and practice for brain-based methods in health and education. This integration of neuroscience and education takes us from a deep understanding of brain function to the frontline of the classroom.

  • Studies in Natural Products Chemistry

    • 1 Edición
    • Volumen 53
    • Atta-ur Rahman
    • Inglés
    Studies in Natural Products Chemistry, Volume 53, covers the synthesis, testing, and recording of the medicinal properties of natural products, providing cutting-edge accounts of the fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis, and pharmacology of a diverse array of bioactive natural products. Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then determine the structures and biological activity of natural products rapidly, thus opening up exciting opportunities in the field of new drug development to the pharmaceutical industry that are discussed and highlighted in this series.

  • Advances in Virus Research

    • 1 Edición
    • Volumen 98
    • Inglés
    Advances in Virus Research, Volume 98, the latest in a series first published in 1953, covers a diverse range of in-depth reviews, providing a valuable overview of the current field of virology. Topics in this new release include Zoonotic Potential of Emerging Paramyxoviruses: Knowns and Unknowns, Metabolomics: Strategies to Define the Role of Metabolism in Virus Infection and Pathogenesis, The Envelope Proteins of the Bunyavirales, and Insect-Specific Viruses: A Historical Overview and Recent Developments. The series is a valuable resource for information on all topics of virus research, from bacteriophages, to human viruses.

  • Hormone Metabolism and Signaling in Plants

    • 1 Edición
    • Jiayang Li + 2 más
    • Inglés
    Plant Hormones: Biosynthesis and Mechanisms of Action is based on research funded by the Chinese government’s National Natural Science Foundation of China (NSFC). This book brings a fresh understanding of hormone biology, particularly molecular mechanisms driving plant hormone actions. With growing understanding of hormone biology comes new outlooks on how mankind values and utilizes the built-in potential of plants for improvement of crops in an environmentally friendly and sustainable manner. This book is a comprehensive description of all major plant hormones: how they are synthesized and catabolized; how they are perceived by plant cells; how they trigger signal transduction; how they regulate gene expression; how they regulate plant growth, development and defense responses; and how we measure plant hormones. This is an exciting time for researchers interested in plant hormones. Plants rely on a diverse set of small molecule hormones to regulate every aspect of their biological processes including development, growth, and adaptation. Since the discovery of the first plant hormone auxin, hormones have always been the frontiers of plant biology. Although the physiological functions of most plant hormones have been studied for decades, the last 15 to 20 years have seen a dramatic progress in our understanding of the molecular mechanisms of hormone actions. The publication of the whole genome sequences of the model systems of Arabidopsis and rice, together with the advent of multidisciplinary approaches has opened the door to successful experimentation on plant hormone actions.

Temas relacionados