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Elsevier

Libros en Ciencias de la Vida

  • Quantitative Human Physiology

    An Introduction
    • 2 Edición
    • Joseph J Feher
    • Inglés
    Quantitative Human Physiology: An Introduction, winner of a 2018 Textbook Excellence Award (Texty), is the first text to meet the needs of the undergraduate bioengineering student who is being exposed to physiology for the first time, but requires a more analytical/quantitat... approach. This book explores how component behavior produces system behavior in physiological systems. Through text explanation, figures, and equations, it provides the engineering student with a basic understanding of physiological principles with an emphasis on quantitative aspects.

  • Nutraceutical and Functional Food Components

    Effects of Innovative Processing Techniques
    • 1 Edición
    • Charis M. Galanakis
    • Inglés
    Nutraceutical and Functional Food Components: Effects of Innovative Processing Techniques presents the latest information on the chemistry, biochemistry, toxicology, health effects, and nutrition characteristics of food components and the recent trends and practices that the food industry (e.g. the implementation of non-thermal technologies, nanoencapsulation, new extraction techniques, and new sources, like by-products, etc.) has adopted. This book fills the gap in knowledge by denoting the impact of recent food industry advances in different parameters of food components (e.g. nutritional value, physical and chemical properties, bioavailability and bioaccessibility characteristics) and final products (e.g. applications, shelf-life, sensory characteristics).

  • The Craft and Science of Coffee

    • 1 Edición
    • Britta Folmer
    • Inglés
    The Craft and Science of Coffee follows the coffee plant from its origins in East Africa to its current role as a global product that influences millions of lives though sustainable development, economics, and consumer desire.For most, coffee is a beloved beverage. However, for some it is also an object of scientifically study, and for others it is approached as a craft, both building on skills and experience. By combining the research and insights of the scientific community and expertise of the crafts people, this unique book brings readers into a sustained and inclusive conversation, one where academic and industrial thought leaders, coffee farmers, and baristas are quoted, each informing and enriching each other.This unusual approach guides the reader on a journey from coffee farmer to roaster, market analyst to barista, in a style that is both rigorous and experience based, universally relevant and personally engaging. From on-farming processes to consumer benefits, the reader is given a deeper appreciation and understanding of coffee's complexity and is invited to form their own educated opinions on the ever changing situation, including potential routes to further shape the coffee future in a responsible manner.

  • Stress: Neuroendocrinology and Neurobiology

    Handbook of Stress Series, Volume 2
    • 1 Edición
    • George Fink
    • Inglés
    Stress: Neuroendocrinology and Neurobiology: Handbook of Stress Series, Volume 2, focuses on neuroendocrinology, the discipline that deals with the way that the brain controls hormonal secretion, and in turn, the way that hormones control the brain. There have been significant advances in our understanding of neuroendocrine molecular and epigenetic mechanisms, especially in the way in which stress-induced hormonal and neurochemical changes affect brain plasticity, neuronal connectivity, and synaptic function. The book features the topic of epigenetics, and how it enables stress and other external factors to affect genetic transmission and expression without changes in DNA sequence. Integrated closely with new behavioral findings and relevance to human disorders, the concepts and data in this volume offer the reader cutting-edge information on the neuroendocrinology of stress. Volume 2 is of prime interest to neuroscientists, clinicians, researchers, academics, and graduate students in neuroendocrinology, neuroscience, biomedicine, endocrinology, psychology, psychiatry, and in some areas of the social sciences, including stress and its management in the workplace.

  • The Vitamins

    Fundamental Aspects in Nutrition and Health
    • 5 Edición
    • Gerald F. Combs Jr. + 1 más
    • Inglés
    The Vitamins: Fundamental Aspects in Nutrition and Health, Fifth Edition, provides the latest coverage of the biochemistry and physiology of vitamins and vitamin-like substances. Health-related themes present insights into the use of vitamins, not only for general nutritional balance, but also as a factor in the prevention and/or treatment of specific health issues, such as overall immunity, inflammatory diseases, obesity, and anemia. Readers will gain an understanding of the roles vitamins play in gene expression and epigenetics, providing important information on the further development of personalized medical treatments that will also allow them to establish appropriate dietary programs based on individual genetic profiles. This cohesive, well-organized presentation of each vitamin includes key words, case studies, and coverage of the metabolic functions of appropriate vitamins. The readability of this complex content is highly regarded by students, instructors, researchers, and professionals alike.

  • Physical Activity and the Aging Brain

    Effects of Exercise on Neurological Function
    • 1 Edición
    • Ronald Ross Watson
    • Inglés
    Physical Activity and the Aging Brain: Effects of Exercise on Neurological Function is a complete guide to the manifold effects of exercise and physical activity on the aging brain. Cognitive decline and motor impairment, onset of diseases and disorders, and even changes in family structure and social settings that occur as we age can all impact activity levels, yet continued physical activity is crucial for successful neurological functioning. This book examines the role that exercise and physical activity play in halting or modulating the deleterious effects of these numerous aging concerns by first examining the current state of research into how exercise manifests physical changes in the brain. It then discuss how physical activity combines with other lifestyle factors to benefit the aging brain, including nutrition, computerized brain training, and social engagement. Most significantly, it also covers how physical activity can serve as therapy to help alleviate the symptoms of various neurological diseases impacting aging populations, with particular emphasis on Alzheimer’s disease and age-related cognitive decline. The book provides broad coverage of the effects of exercise and physical activity on the aging brain, its therapeutic effects, and the many factors that influence the aging process.

  • Functionalized Nanomaterials for the Management of Microbial Infection

    A Strategy to Address Microbial Drug Resistance
    • 1 Edición
    • Rabah Boukherroub + 2 más
    • Inglés
    Functionalized Nanomaterials for the Management of Microbial Infection: A Strategy to Address Microbial Drug Resistance introduces the reader to the newly developing use of nanotechnology to combat microbial drug resistance. Excessive use of antibiotics and antimicrobial agents has produced an inexorable rise in antibiotic resistance in bacterial pathogens. The use of nanotechnology is currently the most promising strategy to overcome microbial drug resistance. This book shows how, due to their small size, nanoparticles can surmount existing drug resistance mechanisms, including decreased uptake and increased efflux of the drug from the microbial cell, biofilm formation, and intracellular bacteria. In particular, chapters cover the use of nanoparticles to raise intracellular antimicrobial levels, thus directly targeting sites of infection and packaging multiple antimicrobial agents onto a single nanoparticle.

  • Krause's Food & the Nutrition Care Process, MEA edition

    • 1 Edición
    • L. Kathleen Mahan + 1 más
    • Inglés
    The Most Authoritative Text on Nutrition for More Than 50 Years. This trusted classic, nicknamed the “nutrition bible,” presents the most cutting-edge and up-to-date dietetics content available in the ever-changing field of nutrition. Students and practitioners alike turn to its current, comprehensive content; engaging pedagogy and design; and logical presentation of information. Written by nearly 50 nationally recognized writers, researchers, and practitioners, it covers nutrition assessment and intervention, the nutritional needs of individuals in different stages of the life cycle, nutrition for health and fitness, and medical nutrition therapy.

  • Global Health Informatics

    How Information Technology Can Change Our Lives in a Globalized World
    • 1 Edición
    • Heimar Marin + 4 más
    • Inglés
    Global Health Informatics: How Information Technology Can Change Our Lives in a Globalized World discusses the critical role of information and communication technologies in health practice, health systems management and research in increasingly interconnected societies. In a global interconnected world the old standalone institutional information systems have proved to be inadequate for patient-centered care provided by multiple providers, for the early detection and response to emerging and re-emerging diseases, and to guide population-oriented public health interventions. The book reviews pertinent aspects and successful current experiences related to standards for health information systems; digital systems as a support for decision making, diagnosis and therapy; professional and client education and training; health systems operation; and intergovernmental collaboration.

  • E-Health Two-Sided Markets

    Implementation and Business Models
    • 1 Edición
    • Vivian Vimarlund
    • Inglés
    E-health two-side Markets: Implementation and Business Models presents empirical models and suggestions that focus on how to remove barriers to deliver online services across borders and how actual barriers affect business models in a two-sided market with regard to eHealth. Technological innovation and business developments in online trade result in fast-evolving markets with the continuous emergence of new products and services, thus requiring a specific approach. This book discusses how to develop innovative and cost-effective implementation strategies for complex organizations, the importance of barriers and facilitators for two-sided markets when implementing e-health services and/or IT based innovations, which pre-requisites have to be achieved in complex organizations that act in two-sided markets when implementing e-services, the ecosystem for implementation of services and innovations in complex organizations, and its effects for business models. This book is a valuable source for researchers in medical informatics, and is also ideal for stakeholders, consultants, advisors, and product designers involved in eHealth services.

  • Soil and Environmental Chemistry

    • 2 Edición
    • William F. Bleam
    • Inglés
    Soil and Environmental Chemistry, Second Edition, presents key aspects of soil chemistry in environmental science, including dose responses, risk characterization, and practical applications of calculations using spreadsheets. The book offers a holistic, practical approach to the application of environmental chemistry to soil science and is designed to equip the reader with the chemistry knowledge and problem-solving skills necessary to validate and interpret data. This updated edition features significantly revised chapters, averaging almost a 50% revision overall, including some reordering of chapters. All new problem sets and solutions are found at the end of each chapter, and linked to a companion site that reflects advances in the field, including expanded coverage of such topics as sample collection, soil moisture, soil carbon cycle models, water chemistry simulation, alkalinity, and redox reactions. There is also additional pedagogy, including key term and real-world scenarios. This book is a must-have reference for researchers and practitioners in environmental and soil sciences, as well as intermediate and advanced students in soil science and/or environmental chemistry.

  • Early Nutrition and Long-Term Health

    Mechanisms, Consequences, and Opportunities
    • 1 Edición
    • Jose M Saavedra + 1 más
    • Inglés
    The nutrition of an individual during gestation and the first two years of life—the first 1,000 days—sets the stage for lifelong health. Nutrition quality and quantity in this period can influence the risk of developing diseases that constitute today’s epidemics. Early-life nutrition can program the body’s tissues, organ structure and function, and metabolic and immunologic responses. These factors impact growth, development and cognition, and the risk of cardiovascular diseases, allergies and obesity. The first part of Early Nutrition and Long-Term Health examines the mechanisms by which early nutrition affects the risk of developing these conditions. The second part of this book reviews specific non-communicable diseases (NCDs) associated with early nutrition. The third part discusses the effects of nutritional programming from fetal life to toddlerhood. Prevention of over- or undernutrition in early life, rather than dietary, behavioral or therapeutic interventions in later life, is likely to have a greater return on society’s investment in coping with the modern epidemic of NCDs.

  • Pediatric Brain Tumors Update, An Issue of Neuroimaging Clinics of North America

    • 1 Edición
    • Volumen 27-1
    • Lara A. Brandão
    • Inglés
    This issue of Neuroimaging Clinics of North America focuses on Pediatric Brain Tumors, and is edited by Dr. Lara A. Brandão. Articles will include: Posterior fossa tumors in pediatric patients; Supratentorial tumors in pediatric patients; Brain tumors in the neonate; Pineal region masses in pediatric patients; Sellar and suprasellar tumors in pediatric patients; Extraparenchymal lesions in pediatric patients; Tumor and tumor-like masses in pediatric patients that involve multiple spaces; Neuroimaging of innovative peptide base vaccine therapy in pediatric brain tumors; Advanced MRI in pediatric brain tumors: clinical applications; and much more!

  • Anti-Angiogenesis Strategies in Cancer Therapies

    • 1 Edición
    • Shaker Mousa + 1 más
    • Inglés
    Anti-angiogenesis Strategies in Cancer Therapeutics provides a detailed look at the current status and future directions in the discovery and development of novel anti-angiogenesis strategies in oncology. This book highlights the different mechanisms involved in the modulation of angiogenesis, including inflammation, thrombosis, and microRNA, and shows how nanotechnology can further enhance the potential of existing and new anti-angiogenesis approaches. Written for industry scientists, researchers, oncologists, hematologists, and professors and students in the field, this comprehensive book covers all aspects of anti-angiogenesis strategies and their differences.

  • PCR Guru

    An Ultimate Benchtop Reference for Molecular Biologists
    • 1 Edición
    • Ayaz Najafov + 1 más
    • Inglés
    PCR Guru: An Ultimate Benchtop Reference for Molecular Biologists is provides researchers in molecular biology with a handy reference for approaching and solving challenging problems associated with PCR setup and optimization. As a laboratory guide, it emphasizes the technical aspects of employing PCR as a tool in molecular biology laboratories. The book covers the history of PCR and the basic science underlying it. It then discusses PCR at the bench level, starting with detailed description and tips on primer design, and continuing with the standard protocols used to perform PCR.

  • Creating a Culture of Accessibility in the Sciences

    • 1 Edición
    • Mahadeo A. Sukhai + 1 más
    • Inglés
    Creating a Culture of Accessibility in the Sciences provides insights and advice on integrating students with disabilities into the STEM fields. Each chapter features research and best practices that are interwoven with experiential narratives. The book is reflective of the diversity of STEM disciplines (life and physical sciences, engineering, and mathematics), and is also reflective of cross-disability perspectives (physical, sensory, learning, mental health, chronic medical and developmental disabilities). It is a useful resource for STEM faculty and university administrators working with students with disabilities, as well as STEM industry professionals interested in accommodating employees with disabilities.

  • Food for the Aging Population

    • 2 Edición
    • Monique Raats + 1 más
    • Inglés
    Food for the Aging Population, Second Edition, is a unique volume that reviews the characteristics of the aging population as food consumers, the role of nutrition in healthy aging, and the design of food products and services for the elderly. The first section of the book discusses the older population as consumers of food and beverages, while the second section covers the extension of functionality into later life. The final section highlights tactics on how to develop food products and services for older people. Fully updated and revised from the first edition, the book covers advances in various fields, introducing a number of new chapters, including, amongst others, topics on the economic determinants of diet in older adults, public policy and older people’s diets, and interventions to support healthy eating in later life.

  • Cardio-Oncology

    Principles, Prevention and Management
    • 1 Edición
    • Roberta A. Gottlieb + 1 más
    • Inglés
    Cardio-Oncology: Principles, Prevention and Management is a clinical volume that focuses on the basic science of cardio-oncology, addresses cardiotoxicity as a consequence of cancer therapy, and discusses prevention, diagnosis and management of cardiovascular disease in patients with cancer. This comprehensive volume presents unique perspectives ranging from basic science to clinical medicine in the field of cardio-oncology. It would be a valuable resource for cardiologists, oncologists, internists, and pediatricians caring for patients with cancer who have cardiovascular risk factors, as well as for cardio-oncology researchers.

  • Metabolism and Pathophysiology of Bariatric Surgery

    Nutrition, Procedures, Outcomes and Adverse Effects
    • 1 Edición
    • Victor R. Preedy + 2 más
    • Inglés
    Pathophysiology of Bariatric Surgery: Metabolism, Nutrition, Procedures, Outcomes and Adverse Effects uses a metabolic and nutritional theme to explain the complex interrelationships between obesity and metabolic profiles before and after bariatric surgery. The book is sectioned into seven distinct areas, Features of Obesity, Surgical Procedures, Nutritional Aspects, Metabolic Aspects, Diabetes, Insulin Resistance and Glucose Control, Cardiovascular and Physiological Effects, and Psychological and Behavioral Effects. Included is coverage on the various types of bariatric surgery, including Roux-en-Y gastric bypass, gastric banding, sleeve gastrectomy, biliopancreatic diversion, and jejunoileal bypass, as well as the variations upon these procedures.

  • Neuro-Ophthalmology, An Issue of Neurologic Clinics

    • 1 Edición
    • Volumen 35-1
    • Andrew G. Lee
    • Inglés
    This issue of Neurologic Clinics, edited by Dr. Andrew Lee, will focus on Neuro-Ophthalmology. The topics covered in the issue include, but are not limited to new treatments for nonarteritic anterior ischemic optic neuropathy; idiopathic intracranial hypertension; neuroimaging for the Horner Syndrome; OCT; erectile dysfunction agents and NAION; NMO; ocular myasthenia gravis; imaging for third nerve palsy; treatment of central retinal artery occlusion; and orbital disease, among others.

  • Biotechnology for Beginners

    • 2 Edición
    • Reinhard Renneberg + 1 más
    • Inglés
    Biotechnology for Beginners, Second Edition, presents the latest information and developments from the field of biotechnology—the applied science of using living organisms and their by-products for commercial development—which has grown and evolved to such an extent over the past few years that increasing numbers of professionals work in areas that are directly impacted by the science. For the first time, this book offers an exciting and colorful overview of biotechnology for professionals and students in a wide array of the life sciences, including genetics, immunology, biochemistry, agronomy, and animal science. This book also appeals to the lay reader without a scientific background who is interested in an entertaining and informative introduction to the key aspects of biotechnology. Authors Renneberg and Demain discuss the opportunities and risks of individual technologies and provide historical data in easy-to-reference boxes, highlighting key topics. The book covers all major aspects of the field, from food biotechnology to enzymes, genetic engineering, viruses, antibodies, and vaccines, to environmental biotechnology, transgenic animals, analytical biotechnology, and the human genome. This stimulating book is the most user-friendly source for a comprehensive overview of this complex field.

  • Clinical and Translational Science

    Principles of Human Research
    • 2 Edición
    • David Robertson + 1 más
    • Inglés
    Clinical and Translational Science: Principles of Human Research, Second Edition, is the most authoritative and timely resource for the broad range of investigators taking on the challenge of clinical and translational science, a field that is devoted to investigating human health and disease, interventions, and outcomes for the purposes of developing new treatment approaches, devices, and modalities to improve health. This updated second edition has been prepared with an international perspective, beginning with fundamental principles, experimental design, epidemiology, traditional and new biostatistical approaches, and investigative tools. It presents complete instruction and guidance from fundamental principles, approaches, and infrastructure, especially for human genetics and genomics, human pharmacology, research in special populations, the societal context of human research, and the future of human research. The book moves on to discuss legal, social, and ethical issues, and concludes with a discussion of future prospects, providing readers with a comprehensive view of this rapidly developing area of science.

  • Imaging Bacterial Molecules, Structures and Cells

    • 1 Edición
    • Volumen 43
    • Inglés
    Imaging Bacterial Molecules, Structures and Cells, the latest volume in the Methods in Microbiology series, provides comprehensive, cutting-edge reviews of current and emerging technologies in the field of clinical microbiology. The book features a wide variety of state-of-the art methods and techniques for the diagnosis and management of microbial infections, with chapters authored by internationally renowned experts. This particular volume focuses on current techniques, such as MALDI-TOF mass spectroscopy and molecular diagnostics, along with newly emerging technologies, such as host-based diagnostics and next generation sequencing.

  • Studies in Natural Products Chemistry

    • 1 Edición
    • Volumen 51
    • Atta-ur Rahman
    • Inglés
    Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then determine the structures and biological activity of natural products rapidly, thus opening up exciting opportunities in the field of new drug development to the pharmaceutical industry. This series covers the synthesis or testing and recording of the medicinal properties of natural products, providing cutting edge accounts of the fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products.

  • Microbial Symbioses

    • 1 Edición
    • Sebastien Duperron
    • Inglés
    Plants and animals have evolved ever since their appearance in a largely microbial world. Their own cells are less numerous than the microorganisms that they host and with whom they interact closely. The study of these interactions, termed microbial symbioses, has benefited from the development of new conceptual and technical tools. We are gaining an increasing understanding of the functioning, evolution and central importance of symbiosis in the biosphere. Since the origin of eukaryotic cells, microscopic organisms of our planet have integrated our very existence into their ways of life. The interaction between host and symbiont brings into question the notion of the individual and the traditional representation of the evolution of species, and the manipulation of symbioses facilitates fascinating new perspectives in biotechnology and health. Recent discoveries show that association is one of the main properties of organisms, making a more integrated view of biology necessary.Microbial Symbioses provides a deliberately “symbiocentric” outlook, to exhibit how the exploration of microbial symbioses enriches our understanding of life, and the potential future for this discipline.

  • Evolution of Nervous Systems

    • 2 Edición
    • Jon H. Kaas + 5 más
    • Inglés
    Evolution of Nervous Systems, Second Edition, Four Volume Set is a unique, major reference which offers the gold standard for those interested both in evolution and nervous systems. All biology only makes sense when seen in the light of evolution, and this is especially true for the nervous system. All animals have nervous systems that mediate their behaviors, many of them species specific, yet these nervous systems all evolved from the simple nervous system of a common ancestor. To understand these nervous systems, we need to know how they vary and how this variation emerged in evolution. In the first edition of this important reference work, over 100 distinguished neuroscientists assembled the current state-of-the-art knowledge on how nervous systems have evolved throughout the animal kingdom. This second edition remains rich in detail and broad in scope, outlining the changes in brain and nervous system organization that occurred from the first invertebrates and vertebrates, to present day fishes, reptiles, birds, mammals, and especially primates, including humans. The book also includes wholly new content, fully updating the chapters in the previous edition and offering brand new content on current developments in the field. Each of the volumes has been carefully restructured to offer expanded coverage of non-mammalian taxa, mammals, primates, and the human nervous system. The basic principles of brain evolution are discussed, as are mechanisms of change. The reader can select from chapters on highly specific topics or those that provide an overview of current thinking and approaches, making this an indispensable work for students and researchers alike.

  • Statistics for Bioinformatics

    Methods for Multiple Sequence Alignment
    • 1 Edición
    • Julie Thompson
    • Inglés
    Statistics for Bioinformatics: Methods for Multiple Sequence Alignment provides an in-depth introduction to the most widely used methods and software in the bioinformatics field. With the ever increasing flood of sequence information from genome sequencing projects, multiple sequence alignment has become one of the cornerstones of bioinformatics. Multiple sequence alignments are crucial for genome annotation, as well as the subsequent structural, functional, and evolutionary studies of genes and gene products. Consequently, there has been renewed interest in the development of novel multiple sequence alignment algorithms and more efficient programs.

  • Orthodontic Applications of Biomaterials

    A Clinical Guide
    • 1 Edición
    • Theodore Eliades + 1 más
    • Inglés
    Orthodontic Applications of Biomaterials: A Clinical Guide reviews the applications of biomaterials and their effects on enamel preparation, bonding, bracket and archwire ligation, mechanotherapy, debonding, and long-term enamel structural, color, and surface effects. The book provides a step-by-step analysis of the phenomena occurring, their clinical importance, and their underlying cause without the use of complex mathematical or physical-chemical analyses, with the goal of providing ‘digestible’ evidence for the clinician.

  • Food Safety and Quality Systems in Developing Countries

    Volume II: Case Studies of Effective Implementation
    • 1 Edición
    • André Gordon
    • Inglés
    Food Safety and Quality Systems in Developing Countries, Volume 2: Case Studies of Effective Implementation begins with a general overview of some of the issues and considerations that impact effective implementation of food safety and quality systems and put this in the context of some of the more noteworthy foodborne illness incidents in the recent past.This book is a rich source of information about the practical application of food science and technology to solving food safety and quality problems in the food industry. Students, researchers, professionals, regulators and market access practitioners will find this book an irreplaceable addition to their arsenal as they deal with issues regarding food safety and quality for the products with which they are working.

  • Navelbine® and Taxotère®

    Histories of Sciences
    • 1 Edición
    • Muriel Le Roux + 1 más
    • Inglés
    Among the many forms of cancer treatment, chemotherapy remains an important part of the arsenal in which Navelbine and Taxotere play a major role.These medicines result from molecules discovered by French researchers of the Institut de Chimie des Substances Naturelles (ICSN) of the CNRS, directed by Pierre Potier. By recounting this history, the authors of this book attempt to illustrate how the work of themselves and others, united in a community, has helped obtain these results. After having explained the strategy of the French policy makers to promote the French chemistry of natural substances, the authors explore how the academic efforts in this field have evolved, and the alignment between science and its applications has become increasingly present. The contributions of the CNRS to the industry, and vice versa, offer an alternative image of public research relationships and industrial research, where CNRS researchers are able to extend the limits of freedom and creativity. It is to account for this complexity that the authors here have chosen to write this history together, which is in a sense exemplary.Due to an association between history and chemistry, this book explains these discoveries by placing them in their specific politic, economic and scientific contexts.

  • Genomic and Precision Medicine

    Foundations, Translation, and Implementation
    • 3 Edición
    • Geoffrey S. Ginsburg + 1 más
    • Inglés
    Genomic and Precision Medicine: Foundations, Translation, and Implementation highlights the various points along the continuum from health to disease where genomic information is impacting clinical decision-making and leading to more personalization of health care. The book pinpoints the challenges, barriers, and solutions that have been, or are being, brought forward to enable translation of genome based technologies into health care. A variety of infrastructure (data systems and EMRs), policy (regulatory, reimbursement, privacy), and research (comparative effectiveness research, learning health system approaches) strategies are also discussed. Readers will find this volume to be an invaluable resource for the translational genomics and implementation science that is required to fully realize personalized health care.

  • 3D Bioprinting

    Fundamentals, Principles and Applications
    • 1 Edición
    • Ibrahim Tarik Ozbolat
    • Inglés
    3D Bioprinting: Fundamentals, Principles and Applications provides the latest information on the fundamentals, principles, physics, and applications of 3D bioprinting. It contains descriptions of the various bioprinting processes and technologies used in additive biomanufacturing of tissue constructs, tissues, and organs using living cells. The increasing availability and decreasing costs of 3D printing technologies are driving its use to meet medical needs, and this book provides an overview of these technologies and their integration. Each chapter discusses current limitations on the relevant technology, giving future perspectives. Professor Ozbolat has pulled together expertise from the fields of bioprinting, tissue engineering, tissue fabrication, and 3D printing in his inclusive table of contents. Topics covered include raw materials, processes, machine technology, products, applications, and limitations. The information in this book will help bioengineers, tissue and manufacturing engineers, and medical doctors understand the features of each bioprinting process, as well as bioink and bioprinter types. In addition, the book presents tactics that can be used to select the appropriate process for a given application, such as tissue engineering and regenerative medicine, transplantation, clinics, or pharmaceutics.

  • Coral Reef Marine Plants of Hainan Island

    • 1 Edición
    • Antoninovich Eduard Titlyanov + 3 más
    • Inglés
    Coral Reef Marine Plants of Hainan Island summarizes the literature on the role and use of marine plants in coral reef ecosystems, especially in China and countries in the Asia-Pacific Region. The first chapter of the book focuses on the description of coral reef ecosystems, their architecture, and status of Hainan coral reefs. The second chapter focuses on common knowledge surrounding marine plants, such as their classification, identifying characteristics of different phyla, morphology, reproduction, life forms, main algal communities on coral reefs, distribution of algae on coral reefs and their roles, and the use of seaweeds in cookery, medicine, industry, and agriculture. The third chapter on the seaweed flora of Hainan Island contains species composition of the marine benthic flora, the complete list of marine plants found by researchers from all studies, and historical changes in the flora and seasonal changes. The final chapter shows how to identify common species of marine plants on coral reefs of Hainan Island. This excellent work will help readers identify relevant plants, also teaching them how to use plant resources to assess endangered states and create conservation strategies.

  • Hyperpolarized and Inert Gas MRI

    From Technology to Application in Research and Medicine
    • 1 Edición
    • Mitchell S. Albert + 1 más
    • Inglés
    Hyperpolarized and Inert Gas MRI: Theory and Applications in Research and Medicine is the first comprehensive volume published on HP gas MRI. Since the 1990’s, when HP gas MRI was invented by Dr. Albert and his colleagues, the HP gas MRI field has grown dramatically. The technique has proven to be a useful tool for diagnosis, disease staging, and therapy evaluation for obstructive lung diseases, including asthma, chronic obstructive pulmonary disease (COPD), and cystic fibrosis. HP gas MRI has also been developed for functional imaging of the brain and is presently being developed for molecular imaging, including molecules associated with lung cancer, breast cancer, and Alzheimer’s disease. Taking into account the ongoing growth of this field and the potential for future clinical applications, the book pulls together the most relevant and cutting-edge research available in HP gas MRI into one resource.

  • The Microbiota in Gastrointestinal Pathophysiology

    Implications for Human Health, Prebiotics, Probiotics, and Dysbiosis
    • 1 Edición
    • Martin H. Floch + 2 más
    • Inglés
    The Microbiota in Gastrointestinal Pathophysiology: Implications for Human Health, Prebiotics, Probiotics and Dysbiosis is a one-stop reference on the state-of-the-art research on gut microbial ecology in relation to human disease. This important resource starts with an overview of the normal microbiota of the gastrointestinal tract, including the esophagus, stomach, Ileum, and colon. The book then identifies what a healthy vs. unhealthy microbial community looks like, including methods of identification. Also included is insight into which features and contributions the microbiota make that are essential and useful to host physiology, as is information on how to promote appropriate mutualisms and prevent undesirable dysbioses. Through the power of synthesizing what is known by experienced researchers in the field, current gaps are closed, raising understanding of the role of the microbiome and allowing for further research.

  • Principles of Animal Research for Graduate and Undergraduate Students

    • 1 Edición
    • Mark A. Suckow + 1 más
    • Inglés
    Principles of Animal Research is the first publication to offer a broad look at animal research science for a student, early researcher, or technician. Offering guidance for all aspects of the research experience, including the research and development of a thesis, model selection, experimental design, IACUC protocol preparation, and animal husbandry and technical procedural needs, the book is a necessary addition to every student, technician, and researcher’s education.

  • Neuropsychiatric Disorders and Epigenetics

    • 1 Edición
    • Jacob Peedicayil + 1 más
    • Inglés
    Neuropsychiatric Disorders and Epigenetics is a comprehensive reference for the epigenetic basis of most common neuropsychiatric disorders. The volume is organized into chapters representing individual neuropsychiatric disorders, from addition to obesity contributed by leading experts in their respective fields. The epigenetic aspects of each disorder are discussed, in the context of the full range of epigenetic mechanisms including DNA modification, histone post-translational modification, chromatin organization and non-coding RNA. A particular emphasis is placed on potential epigenetic interventions, when the effects of environmental stimuli on epigenetic states is particularly relevant o disease. Recent discoveries in epigenetic research enabled by epic advances in genomic technologies have positioned the field for broad translation to therapeutic interventions for previously unmanageable disorders Neuropsychiatric disorders represent a prime target of epigenetic interventions as they are highly debilitating, often chronic diseases with enormous costs to society. Thus, this volume will help define epigenetics as a key player in neuropsychiatric disorders, highlighting the full spectrum of epigenetic mechanisms underlying such disorders and introducing the vast range of epigenetic therapies under development.

  • Introduction to Cancer Metastasis

    • 1 Edición
    • Aamir Ahmad
    • Inglés
    Introduction to Cancer Metastasis provides, in one place, an overview of organ-specific cancer metastasis and the most common sites of cancer metastasis. Through specific chapters on individual primary cancers, their metastasis, and chapters on common metastatic sites, this volume comprehensively informs readers about the broader knowledge base in cancer metastasis. The process of metastasis is particularly responsible for making cancer so lethal. This volume explores both metastasis from sites of origin and common metastatic sites, thus increasing understanding of both perspectives.

  • Molecular and Cellular Changes in the Cancer Cell

    • 1 Edición
    • Volumen 144
    • Inglés
    Molecular and Cellular Changes in the Cancer Cell,the latest volume in the Progress in Molecular Biology and Translational Science series, includes a comprehensive summary of the evidence accumulated thus far on the molecular and cellular regulation of the various adaptations taking place in response to exercise. This volume examines some of the latest advances, highlighting some of the most important molecular and cellular alterations and environmental influences that collectively cause a normal cell to become cancerous. Special emphasis is given to changes that take place at the molecular and cellular level.

  • Metallic Foam Bone

    Processing, Modification and Characterization and Properties
    • 1 Edición
    • Cuie Wen
    • Inglés
    Metallic Foam Bone: Processing, Modification and Characterization and Properties examines the use of porous metals as novel bone replacement materials. With a strong focus on materials science and clinical applications, the book also examines the modification of metals to ensure their biocompatibility and efficacy in vivo. Initial chapters discuss processing and production methods of metals for tissue engineering and biomedical applications that are followed by topics on practical applications in orthopedics and dentistry. Finally, the book addresses the surface science of metallic foam and how it can be tailored for medical applications. This book is a valuable resource for materials scientists, biomedical engineers, and clinicians with an interest in innovative biomaterials for orthopedic and bone restoration.

  • Pharmacognosy

    Fundamentals, Applications and Strategies
    • 1 Edición
    • Rupika Delgoda
    • Simone Badal McCreath
    • Inglés
    Pharmacognosy: Fundamentals, Applications and Strategies explores a basic understanding of the anatomy and physiology of plants and animals, their constituents and metabolites. This book also provides an in-depth look at natural sources from which medicines are derived, their pharmacological and chemical properties, safety aspects, and how they interact with humans. The book is vital for future research planning, helping readers understand the makeup, function, and metabolites of plants in a way where the history of their usage can be linked to current drug development research, including in vitro, in vivo, and clinical research data. By focusing on basic principles, current research, and global trends, this book provides a critical resource for students and researchers in the areas of pharmacognosy, pharmacy, botany, medicine, biotechnology, biochemistry, and chemistry.

  • Anticancer Treatments and Cardiotoxicity

    Mechanisms, Diagnostic and Therapeutic Interventions
    • 1 Edición
    • Patrizio Lancellotti + 2 más
    • Inglés
    Anticancer Treatments and Cardiotoxicity: Mechanisms, Diagnostic and Therapeutic Interventions presents cutting edge research on the adverse cardiac effects of both radiotherapy and chemotherapy, brought together by leaders in the field. Cancer treatment-related cardiotoxicity is the leading cause of treatment-associated mortality in cancer survivors and is one of the most common post-treatment issues among survivors of adult cancer. Early detection of the patients prone to developing cardiotoxicity, taking in to account the type of treatment, history and other risk factors, is essential in the fight to decrease cardiotoxic mortality. This illustrated reference describes the most effective diagnostic and imaging tools to evaluate and predict the development of cardiac dysfunction for those patients undergoing cancer treatment. In addition, new guidelines on imaging for the screening and monitoring of these patients are also presented. Anticancer Treatments and Cardiotoxicity is an essential reference for those involved in the research and treatment of cardiovascular toxicity.

  • Advances in Molecular Toxicology

    • 1 Edición
    • Volumen 10
    • Inglés
    Advances in Molecular Toxicology features the latest advances in the subspecialties of the broad area of molecular toxicology. This series details the study of the molecular basis of toxicology by which a vast array of agents encountered in the human environment, and produced by the human body, manifest themselves as toxins. The book is not strictly limited to documenting these examples, but also covers the complex web of chemical and biological events that give rise to toxin-induced symptoms and disease. The new technologies that are being harnessed to analyze and understand these events are also reviewed by leading experts in the field.

  • Monitoring and Evaluation of Biomaterials and their Performance In Vivo

    • 1 Edición
    • Roger Narayan
    • Inglés
    Monitoring and Evaluation of Biomaterials and Their Performance In Vivo provides essential information for scientists and researchers who need to assess and evaluate performance, monitor biological responses, gauge efficacy, and observe changes over time. Crucially, it also enables the optimization of design for future biomaterials and implants. This book presents readers with comprehensive coverage of the topic of in vivo monitoring of medical implants and biomaterials.

  • The Microbiological Quality of Food

    Foodborne Spoilers
    • 1 Edición
    • Antonio Bevilacqua + 2 más
    • Inglés
    The Microbiological Quality of Food: Foodborne Spoilers specifically addresses the role of spoilers in food technology and how they affect the quality of food. Food spoilers represent a great challenge in food quality, determining the shelf-life of many products as they impact consumer acceptability of taste, texture, aroma, and other perceptions. Divided into four sections, the first section defines microbial spoilage of food, with special emphasis on methods for the evaluation of spoiling phenomena and the status of their regulatory framework, examining both existing regulations and possible gaps. The second section examines spoiling microorganisms, covering a range of common spoilage microorganisms, including pseudomonas, yeasts, and molds and spore formers, as well as less-common spoilers, including lactic acid bacteria and specific spoilage organisms in fish. The third section highlights spoiling phenomena within certain food types. Chapters cover dairy, fish, meat, and vegetables, and other products. The final section investigates emerging topics which point to future trends in the research of food spoilers. There is insight into microorganisms resistant to preservation, the role of biofilms in food quality, and the link between food safety and food spoilage, with a special emphasis on certain spoiling microorganisms which could be opportunistic pathogens. Written by an international team of leading authors, this book provides state-of-the-art coverage of this topic, which is essential to the shelf-life and quality of food.

  • Non-Equilibrium States and Glass Transitions in Foods

    Processing Effects and Product-Specific Implications
    • 1 Edición
    • Bhesh Bhandari + 1 más
    • Inglés
    Non-equilibrium States and Glass Transitions in Foods: Processing Effects and Product Specific Implications presents the tactics needed to understand and control non-equilibrium states and glass transitions in food, an essential element in maintaining the shelf-life and quality of foods. After brief introductory chapters introduce the science behind non-equilibrium states and glass transitions in foods, the book details how glass transition temperature is affected by composition and the ways it influences processability and physico-chemical changes during the storage of foods, also exploring how these effects can be controlled. The second section looks at individual foods, highlighting the implications of non-equilibrium states and glass transitions within these foods. Maintaining and improving the quality of food is of upmost importance to food companies who have to ensure that the shelf life of their products is as long as possible. A large amount of research has been performed into glass transitions in food over the last few years, however there has not been a comprehensive review. This book fills that gap.

  • Soil Magnetism

    Applications in Pedology, Environmental Science and Agriculture
    • 1 Edición
    • Neli Jordanova
    • Inglés
    Soil Magnetism: Applications in Pedology, Environmental Science and Agriculture provides a systematic, comparative, and detailed overview of the magnetic characterization of the major soil units and the observed general relationships, possibilities, and perspectives in application of rock magnetic methods in soil science, agriculture, and beyond. Part I covers detailed magnetic and geochemical characterization of major soil types according to the FAO classification system, with Part II covering the mapping of topsoil magnetic signatures on the basis of soil magnetic characteristics. The book concludes with practical examples on the application of magnetic methods in environmental science, agriculture, soil pollution, and paleoclimate.

  • Hormones, Brain and Behavior

    • 3 Edición
    • Donald W. Pfaff + 1 más
    • Inglés
    Hormones, Brain and Behavior, Third Edition offers a state-of-the-art overview of hormonally-mediated behaviors, including an extensive discussion of the effects of hormones on insects, fish, amphibians, birds, rodents, and humans. Entries have been carefully designed to provide a valuable source of information for students and researchers in neuroendocrinology and those working in related areas, such as biology, psychology, psychiatry, and neurology. This third edition has been substantially restructured to include both foundational information and recent developments in the field. Continuing the emphasis on interdisciplinary research and practical applications, the book includes articles aligned in five main subject sections, with new chapters included on genetic and genomic techniques and clinical investigations. This reference provides unique treatment of all major vertebrate and invertebrate model systems with excellent opportunities for relating behavior to molecular genetics. The topics cover an unusual breadth (from molecules to ecophysiology), ranging from basic science to clinical research, making this reference of interest to a broad range of scientists in a variety of fields.

  • Fenner and White's Medical Virology

    • 5 Edición
    • Christopher J. Burrell + 2 más
    • Inglés
    Fenner and White's Medical Virology, Fifth Edition provides an integrated view of related sciences, from cell biology, to medical epidemiology and human social behavior. The perspective represented by this book, that of medical virology as an infectious disease science, is meant to provide a starting point, an anchor, for those who must relate the subject to clinical practice, public health practice, scholarly research, and other endeavors. The book presents detailed exposition on the properties of viruses, how viruses replicate, and how viruses cause disease. These chapters are then followed by an overview of the principles of diagnosis, epidemiology, and how virus infections can be controlled. The first section concludes with a discussion on emergence and attempts to predict the next major public health challenges. These form a guide for delving into the specific diseases of interest to the reader as described in Part II. This lucid and concise, yet comprehensive, text is admirably suited to the needs of not only advanced students of science and medicine, but also postgraduate students, teachers, and research workers in all areas of virology.

  • Diabetes, An Issue of Endocrinology and Metabolism Clinics of North America

    • 1 Edición
    • Volumen 45-4
    • S. Sethu K. Reddy
    • Inglés
    This issue of Endocrinology and Metabolism Clinics, guest edited by Dr. Sethu K. Reddy, is devoted to Diabetes. Articles in this issue include: Approach to Multicultural Issues in Diabetes; Clinical Utility of Genetic Testing in T2DM; Utility of CGM - Type 1 and Type 2 Diabetes Mellitus; Islet Cell Transplantation; Use of Telemedicine; Nonalcoholic Steatohepatitis; Microbiome: Role in Type 1 and Type 2 Diabetes Mellitus; Population Management and Diabetes; Pre-diabetes; Metformin: What do we know?; Insulin: Making Sense of Current Options; Nutrition in Diabetes; Bariatric Surgery: Pathophysiology and Outcomes; Future Therapies in Diabetes; Lipodystrophic Syndromes; and In-patient Diabetes Management in the 21st Century.

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