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Elsevier

Libros en Ciencias de la Vida

  • Kiwifruit

    The Genus ACTINIDIA
    • 1 Edición
    • Hongwen Huang
    • Inglés
    Kiwifruit: The Genus ACTINIDIA includes extensive and full coverage of scientific and applied information, ranging from basic taxonomy, population genetics, and natural resources/distributi... to domestication history and breeding/cultivars, also including further information on culture and international production and commercialization. The book gathers information not previously available in the English language, providing an authoritative reference for professionals, including taxonomists, horticulturist, breeders, conservationists, kiwifruit technicians, college teachers, policymakers in the industry, and governments. In addition to those in the academic and professional sectors, horticultural and botanical enthusiasts will find the information presented highly accessible.

  • Antiphospholipid Syndrome in Systemic Autoimmune Diseases

    • 2 Edición
    • Volumen 12
    • R. Cervera + 3 más
    • Inglés
    Antiphospholipid Syndrome in Systemic Autoimmune Diseases, Second Edition provides an overview of our current understanding of this major disease. It includes the latest information on the new pathogenetic mechanisms involved, along with clinical manifestations in both the thrombotic and non-thrombotic manifestations of this important disease. Antiphospholipid syndrome is an autoimmune disease that causes abnormal blood clots. It is now recognized as a major cause of common conditions, including stroke, heart attack, miscarriage, epilepsy, and memory loss, and as such is gaining recognition in all branches of medicine, from obstetrics to cardiology, and from psychiatry to orthopedics.

  • Advances in Food Traceability Techniques and Technologies

    Improving Quality Throughout the Food Chain
    • 1 Edición
    • Montserrat Espiñeira + 1 más
    • Inglés
    Advances in Food Traceability Techniques and Technologies: Improving Quality Throughout the Food Chain covers in detail a topic of great importance to both the food industry which is obliged to provide clear and accurate labeling of their products and the government and other organizations which are tasked with verification of claims of food quality and safety. The traceability of food products is becoming ever more important as globalization continues to increase the complexity of food chains. Coverage in the book includes the wide range of technologies and techniques which have been utilized in the tracing of food products. In addition, the ways in which the misuse of food traceability will affect the quality of food is also covered throughout. The first part of the book introduces the concept of traceability in the food industry, highlighting advantages of a robust traceability and the difficulties involved in implementing them. The second part looks at the technologies used to trace products, and the third section reviews the legal requirements for food traceability in the EU, the US, and the rest of the world. The final section contains a number of case studies which evaluate how food traceability has been successfully implemented in various foods focusing on the quality of the food.

  • Mechanisms of Sensory Working Memory

    Attention and Perfomance XXV
    • 1 Edición
    • Pierre Jolicoeur + 2 más
    • Inglés
    Mechanisms of Sensory Working Memory: Attention and Performance XXV provides an update on research surrounding the memory processes that are crucial for many facets of cognitive processing and experience, with new coverage of emerging areas of study, including a new understanding of working memory for features of stimuli devoid of verbal, phonological, or long-term memory content, such as memory for simple visual features (e.g., texture or color), simple auditory features (e.g., pitch), or simple tactile features (e.g., vibration frequency), now called sensory memory to distinguish from verbal memory. This contemporary focus on sensory memory is just beginning, and this collection of original contributions provides a foundational reference for the study mechanisms of sensory memory. Students, scholars, and researchers studying memory mechanisms and processes in cognitive neuroscience, cognitive science, neuroscience, and psychology will find this book of great value to their work.

  • Neurobiology of Epilepsy

    From Genes to Networks
    • 1 Edición
    • Volumen 226
    • Inglés
    Neurobiology of Epilepsy: From Genes to Networks is the latest volume in the Progress in Brain Research series that focuses on new trends and developments. This established international series examines major areas of basic and clinical research within the neurosciences, as well as popular and emerging subfields.

  • Fungal Toxins

    A Comprehensive Treatise
    • 1 Edición
    • Alex Ciegler + 2 más
    • Inglés
    Microbial Toxins, Volume VI: Fungal Toxins covers information on the evaluation of the chemical, biological, and biomedical aspects of the fungal toxins. The book discusses the historical structure chemistry, production, analysis, detoxification, biosynthesis, pharmacology, toxicology, and molecular biochemistry of aflatoxins and related compounds. The text also describes the isolation, analysis, production, chemistry, biological effects, and biogenesis of the ochratoxins, as well as the bioproduction, biosynthesis, and chemical properties of misclellaneous Aspergillus toxins. Various species of storage fungi, including yellowed rice toxins, luteoskyrin and related compounds, chlorine-containing compounds, citrinin, and citreoviridin are also considered. The book further tackles the physical and chemical properties and the biological activity of the rubratoxins; the biosynthesis and biochemical effects of patulin, penicillic acid, and other carcinogenic lactones; as well as the structure, production, biosynthesis, and biological effects of cyclopiazonic acid and related toxins. The text also encompasses bioproduction, properties, chemical structure, and biological activity of miscellaneous Penicillium toxins. Microbiologists, biochemists, epidemiologists, pharmacologists, toxicologists, medical students and people involved in other related fields will find the book useful.

  • Informed and Healthy

    Theoretical and Applied Perspectives on the Value of Information to Health Care
    • 1 Edición
    • Maria G. N. Musoke
    • Inglés
    Informed and Healthy: Theoretical and Applied Perspectives on the Value of Information to Health Care focuses on two major issues: the value attributed to information by users and its effect on health care; and, a new model of information behavior in which the value of information drives various information activities (unlike many information models which tend to give prominence to information needs). The inductive development of the model is explained, with associated implications for theory and transferability or applicability elsewhere. The book uses a case study of the health information system in Uganda and expands the analysis by comparing it to other systems utilized by different countries in diverse levels of development. Topics such as access and use of information; value attribution and effect on health outcomes; and modelling information behavior and its implications on health informatics are discussed in detail. This book is a valuable resource for health professionals, planners, and policy makers, as well as researchers interested in health information systems and their applicability in different environments.

  • Calculations for Molecular Biology and Biotechnology

    • 3 Edición
    • Frank H. Stephenson
    • Inglés
    Calculations in Molecular Biology and Biotechnology, Third Edition, helps researchers utilizing molecular biology and biotechnology techniques—from student to professional—underst... which type of calculation to use and why. Research in biotechnology and molecular biology requires a vast amount of calculations. Results of one data set become the basis of the next. An error of choosing the wrong type of equation can turn what would have been a successful research project or weeks of labor and research into a veritable house of cards. It could be how you calculated the medium in which you test your sample to calculating how long it takes a sample to grow to calculating the synthesis of multiple variables. In one easy to use reference, Stephenson reviews the mathematics and statistics related to the day-to-day functions of biotechnology and molecular biology labs, which is a sticking point for many students, technicians, and researchers. The book covers all of the basic mathematical and statistical needs for students and professionals, providing them with a useful tool for their work.

  • Sport and Exercise Psychology Research

    From Theory to Practice
    • 1 Edición
    • Markus Raab + 4 más
    • Inglés
    Sport and Exercise Psychology Research: From Theory to Practice provides a comprehensive summary of new research in sport and exercise psychology from worldwide researchers. Encompassing theory, research, and applications, the book is split into several themed sections. Section 1 discusses basic antecedents to performance including fitness, practice, emotion, team dynamics, and more. Section 2 identifies factors influencing individual performance. Section 3 discusses applied sport psychology for athletes and coaches, and section 4 includes approaches from exercise psychology on motivation and well-being. The book includes a mix of award winning researchers from the European Sport Psychology Association, along with top researchers from the U.S. to bring an international overview to sport psychology.

  • Bacterial Endotoxins

    A Comprehensive Treatise
    • 1 Edición
    • Solomon Kadis + 2 más
    • Inglés
    Microbial Toxins, Volume V: Bacterial Endotoxins covers the physiology, pathology, and immunology of bacterial endotoxins. The book discusses the relationship of lipopolysaccharide structure to bacterial virulence; the importance of blood-group and Forssman antigenic determinants in interactions between human and microbes; and the chemical modification of endotoxin and inactivation of its biological properties. The text also describes the effects of endotoxic lipopolysaccharides on the complement system; the host-dependent detoxification of bacterial endotoxin; and the metabolic effects of bacterial endotoxins. The release of vasoactive agents and the vascular effects of endotoxin are also considered. The book further tackles the febrile response to endotoxin; some major aspects and the relationship between shock and endotoxemia; as well as the effects of lipopolysaccharides (endotoxins) on the susceptibility to infections. The text also encompasses the role of hypersensitivity and tolerance in reactions to endotoxins. Pathologists, immunologists, physiologists, and microbiologists will find the book invaluable.

  • Introduction to the Principles of Drug Design

    • 1 Edición
    • H. J. Smith + 1 más
    • Inglés
    Introduction to the Principles of Drug Design provides a framework of fundamental drug design and principles into which drugs following on developments may be fitted. This book presents the rationales behind the design of drugs. Organized into nine chapters, this book begins with an overview of how the body handles a drug in terms of absorption, metabolism, distribution, and excretion. This text then examines the critical drug activity at the receptor site, which is usually related to blood and other distribution fluid levels. Other chapters consider the factors involved in binding a drug, metabolite, or substrate to a receptor. The final chapter deals with the design of chemotherapeutic agent for clinical use in the treatment of human infections. This book is intended for use in undergraduate pharmacy courses in medicinal chemistry and as an aid in similar courses in biochemistry and pharmacology. Graduates in chemistry just entering the pharmaceutical industry will also find this book useful.

  • Dynemicin A, Uncialamycin and Analogues

    • 1 Edición
    • Daniel Best + 2 más
    • Inglés
    Enediynes are natural products with highly active cytotoxicity and antibacterial activity, and thus have significant potential in the development of anti-cancer treatments. However, they are not readily available and can degrade rapidly during isolation; one solution is to produce them using total synthesis.Dynemicin A and uncialamycin are two such enediynes, with similar structures, for which total synthesis has been achieved. This book presents the isolation and preparation of these two compounds and their analogues through various synthesis strategies. Details of the structural elements essential to their anti-cancer activity are presented, with the objective of explaining and optimizing their biological activities and potential development as drugs.

  • Environmental Stresses in Soybean Production

    Soybean Production Volume 2
    • 1 Edición
    • Mohammad Miransari
    • Inglés
    Environmental Stress Conditions in Soybean Production: Soybean Production, Volume Two, examines the impact of conditions on final crop yield and identifies core issues and methods to address concerns. As climate and soil quality changes and issues continue to manifest around the world, methods of ensuring sustainable crop production is imperative. The care and treatment of the soil nutrients, how water availability and temperature interact with both soil and plant, and what new means of crop protection are being developed make this an important resource for those focusing on this versatile crop. The book is a complement to volume one, Abiotic and Biotic Stresses in Soybean Production, providing further insights into crop protection.

  • Antibiotic Resistance

    Mechanisms and New Antimicrobial Approaches
    • 1 Edición
    • Kateryna Kon + 1 más
    • Inglés
    Antibiotic Resistance: Mechanisms and New Antimicrobial Approaches discusses up-to-date knowledge in mechanisms of antibiotic resistance and all recent advances in fighting microbial resistance such as the applications of nanotechnology, plant products, bacteriophages, marine products, algae, insect-derived products, and other alternative methods that can be applied to fight bacterial infections. Understanding fundamental mechanisms of antibiotic resistance is a key step in the discovery of effective methods to cope with resistance. This book also discusses methods used to fight antibiotic-resistant infection based on a deep understanding of the mechanisms involved in the development of the resistance.

  • Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging

    Volume 10
    • 1 Edición
    • M. A. Hayat
    • Inglés
    Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging, Volume 10 offer a valuable guide to both cellular processes, while encouraging researchers to explore their potentially important connections. Autophagy serves to maintain healthy cells, tissues, and organs, but also promotes cancer survival and growth of established tumors. Impaired or deregulated autophagy can also contribute to disease pathogenesis. This is the tenth volume of the multivolume series that discusses, in detail, almost all aspects of the autophagy machinery in the context of health, cancer, and other pathologies. Autophagy maintains homeostasis during starvation or stress conditions by balancing the synthesis of cellular components and their deregulation by autophagy. Volume 10 of the Autophagy series discusses the role of a novel binuclear palladacycle complex that inhibits melanoma growth through apoptosis and autophagy.

  • Pesticides in the Soil Environment

    • 1 Edición
    • Shahamat U. Khan
    • R. J. Wakeman
    • Inglés
    Fundamental Aspects of Pollution Control and Environmental Science, 5: Pesticides in the Soil Environment focuses on the effects of pesticide use on the quality of soil. The manuscript first offers information on the classification of pesticides and physicochemical processes affecting pesticides in soil. Topics include herbicides, fungicides, movement in soil, chemical conversion and degradation, and photodecomposition. The text then elaborates on microbial processes affecting pesticides in soil, including fumigants, fungicides, and insecticides. The text examines the occurrence and persistence of pesticide residues in soil and minimizing pesticide residues in soil. Discussions focus on persistence, bound residues, plant uptake, short residual residues, and eliminating pesticide residues. The text is a dependable reference for readers interested in the effects of pesticide use on the quality of soil.

  • The Zebrafish: Cellular and Developmental Biology, Part B Developmental Biology

    • 4 Edición
    • Volumen 134
    • Inglés
    The Zebrafish: Cellular and Developmental Biology, Part B Developmental Biology, the second volume on the topic in the Methods in Cell Biology series, looks at methods for analyzing cellular and developmental biology of zebrafish. Chapters cover such topics as cell biology and developmental and neural biology.

  • Emulsions

    • 1 Edición
    • Volumen 3
    • Alexandru Grumezescu
    • Inglés
    Emulsions, the third volume of the Nanotechnology in the Food Industry series, is an invaluable resource for anyone in the food industry who needs the most recent information about scientific advances in nanotechnology on this topic. This volume focuses on basic and advanced knowledge about nanoemulsion, and presents an overview of the production methods, materials (solvents, emulsifiers, and functional ingredients), and current analytical techniques that can be used for the identification and characterization of nanoemulsions. The book also discusses the applications of nanoemulsion with special emphasis on systems suitable for utilization within the food industry. This book is useful to a wide audience of food science research professionals and students who are doing research in this field, as well as others interested in recent nanotechnological progress worldwide.

  • Artificial Photosynthesis

    • 1 Edición
    • Volumen 79
    • Inglés
    Artificial Photosynthesis, the latest edition in the Advances in Botanical Research series, which publishes in-depth and up-to-date reviews on a wide range of topics in the plant sciences features several reviews by recognized experts on all aspects of plant genetics, biochemistry, cell biology, molecular biology, physiology, and ecology.

  • Regenerative Medicine for Peripheral Artery Disease

    • 1 Edición
    • Emile R Mohler + 1 más
    • Inglés
    Regenerative Medicine for Peripheral Artery Disease is a comprehensive and up-to-date resource on the use of regenerative medicine for the treatment of peripheral arterial disease. This reference includes a general overview of regenerative medicine and covers important vascular topics, including intermittent claudication and critical limb ischemia, with important mechanisms clearly presented in full color images throughout the book. This important reference includes clear and concise information on both human clinical trials, as well as important and pertinent animal studies, and is a must-have reference for researchers and practitioners of peripheral artery disease.

  • Nano- and Microfabrication for Industrial and Biomedical Applications

    • 2 Edición
    • Regina Luttge
    • Inglés
    Nano- and Microfabrication for Industrial and Biomedical Applications, Second Edition, focuses on the industrial perspective on micro- and nanofabrication methods, including large-scale manufacturing, the transfer of concepts from lab to factory, process tolerance, yield, robustness, and cost. The book gives a history of miniaturization and micro- and nanofabrication, and surveys industrial fields of application, illustrating fabrication processes of relevant micro and nano devices. In this second edition, a new focus area is nanoengineering as an important driver for the rise of novel applications by integrating bio-nanofabrication into microsystems. In addition, new material covers lithographic mould fabrication for soft-lithography, nanolithography techniques, corner lithography, advances in nanosensing, and the developing field of advanced functional materials. Luttge also explores the view that micro- and nanofabrication will be the key driver for a "tech-revolution" in biology and medical research that includes a new case study that covers the developing organ-on-chip concept.

  • Bubbles in Food 2

    Novelty, Health and Luxury
    • 1 Edición
    • Grant Campbell
    • Inglés
    Bubbles give novelty and distinctiveness to many food and drink products including the most important and interesting ones such as bread, beer, ice cream, whipped cream, soufflés and champagne. Understanding the creation and control of bubbles in food products is key to the success of the domestic chef or the industrial food manufacturer. This new volume presents the proceedings of the conference Bubbles in Food 2: Novelty, Health and Luxury. This book is fully updated and expanded from the original Bubbles in Food book published in 1999. This new title brings together up-to-date information on the latest developments in this fast moving area. Bubbles in Food 2 includes novel experimental techniques for measuring and quantifying the aerated structure of foods (e.g. ultrasonics, MRI imaging, X-ray tomography, microscopy, rheology, image analysis), and novel analytical approaches for interpreting aerated food properties and behavior. These techniques and approaches provide stimulus for new product development or for enhancing the understanding of the manufacture of existing products, leading to enhanced quality and greater product differentiation. Bubbles in Food 2: Novelty, Health and Luxury aims to enhance the appreciation of aerated foods and to provide stimulation and cross fertilisation of ideas for the exploitation of bubbles as a novel and versatile food ingredient.

  • Wheat: Chemistry and Technology

    • 4 Edición
    • Khalil Khan
    • Inglés
    Wheat science has undergone countless new developments since the previous edition was published. Wheat: Chemistry and Technology, Fourth Edition ushers in a new era in our knowledge of this mainstay grain. This new edition is completely revised, providing the latest information on wheat grain development, structure, and composition including vital peer-reviewed information not readily available online. It contains a wealth of new information on the structure and functional properties of gluten (Ch. 6), micronutrients and phytochemicals in wheat grain (Ch. 7), and transgenic manipulation of wheat quality (Ch. 12). With the new developments in molecular biology, genomics, and other emerging technologies, this fully updated book is a treasure trove of the latest information for grain science professionals and food technologists alike. Chapters on the composition of wheat—proteins (Ch. 8), carbohydrates (Ch. 9) lipids (Ch. 10), and enzymes (Ch. 11.), have been completely revised and present new insight into the important building blocks of our knowledge of wheat chemistry and technology. The agronomical importance of the wheat crop and its affect on food industry commerce provide an enhanced understanding of one of the world’s largest food crop. Most chapters are entirely rewritten by new authors to focus on modern developments. This 480-page monograph includes a new large 8.5” x 11” two-column format with color throughout and an easy to read style. Wheat: Chemistry and Technology, Fourth Edition provides a comprehensive background on wheat science and makes the latest information available to grain science professionals at universities, institutes, and industry including milling and baking companies, and anywhere wheat ingredients are used. This book will also be a useful supplementary text for classes teaching cereal technology, cereal science, cereal chemistry, food science, food chemistry, milling, and nutritional properties of cereals. Cereal and food science graduate students will find Chapter 1 – “Wheat: A Unique Grain for the World” particularly helpful because it provides a succinct summary of wheat chemistry.

  • Innovation Strategies in the Food Industry

    Tools for Implementation
    • 1 Edición
    • Charis M. Galanakis
    • Inglés
    Innovation Strategies in the Food Industry: Tools for Implementation is an indispensable resource for the food industry to introduce innovations in the market, stand out from the competition and satisfy consumer demands. This reference reports the most trend advances of the food science, while providing insights and ideas to overcome limitations for their actual implementation in the industry. Innovation Strategies in the Food Industry: Tools for Implementation fills the gap between strategy developers and technical R&D associates by interpreting the technological adequacy of innovative techniques with the reaction of related consumers. It deals with the interaction of academia and industry, describing innovation and long term R&D strategies to overcome bottlenecks during know-how transfer between these two sectors.

  • Landmark Experiments in Molecular Biology

    • 1 Edición
    • Michael Fry
    • Inglés
    Landmark Experiments in Molecular Biology critically considers breakthrough experiments that have constituted major turning points in the birth and evolution of molecular biology. These experiments laid the foundations to molecular biology by uncovering the major players in the machinery of inheritance and biological information handling such as DNA, RNA, ribosomes, and proteins. Landmark Experiments in Molecular Biology combines an historical survey of the development of ideas, theories, and profiles of leading scientists with detailed scientific and technical analysis.

  • Handbook of Hygiene Control in the Food Industry

    • 2 Edición
    • John Holah + 2 más
    • Inglés
    Handbook of Hygiene Control in the Food Industry, Second Edition, continues to be an authoritative reference for anyone who needs hands-on practical information to improve best practices in food safety and quality. The book is written by leaders in the field who understand the complex issues of control surrounding food industry design, operations, and processes, contamination management methods, route analysis processing, allergenic residues, pest management, and more. Professionals and students will find a comprehensive account of risk analysis and management solutions they can use to minimize risks and hazards plus tactics and best practices for creating a safe food supply, farm to fork.

  • Consumer Driven Cereal Innovation

    Where Science Meets Industry
    • 1 Edición
    • Peter Weegels
    • Inglés
    Consumer Driven Cereal Innovation: Where Science Meets Industry includes a collection of papers from oral and poster presentations, along with all the abstracts from the first Spring Meeting organized by Cereals&Europe, the European section of AACC International. These proceedings discuss the major innovation challenges the cereal industry is facing to meet consumers’ demands and expectations. Consumers’ needs are perhaps best summarized as foods that are safe, healthy, and tasty. This book helps answer important questions regarding these essential needs. With respect to safety, the cereal industry can already boast of an excellent reputation and a long tradition of safeguarding cereals and their products. But how can one define “healthy”? How does one distinguish between reality and fiction? If the best ways to add health benefits to cereal products are to be determined, the consumer’s palate needs first to be pleased. What are the most cost-effective ways to manufacture grain-based products for safety, health, and palatability? This conference addressed these important questions and this book is the result of the research and insights of many of the brightest minds in grain science today. Areas of Focus - Consumer Driven Cereal Innovation Conference Proceedings Plenary – Papers from Invited Lecturers:Consumer Attitudes Towards Healthy Cereal ProductsConsumer, Cereals and Health: Trends, Fads and RealityHealth Benefits of Whole Grain Products Science Track:Consumer Insights and Nutritional Aspects of Innovative Cereal-based Products- Nutritional and Sensory Quality- PhysiologyCereals: Source of High Quality Nutrients- Regulation and Functional Nutrients- Methodology Technology Track:Better processes for Better NutritionBioactive IngredientsProduct Quality- Product Texture and Quality- Shelf Life- Toxicology

  • Fundamentals of Stored-Product Entomology

    • 1 Edición
    • David Hagstrum
    • Inglés
    This reference discusses the fundamentals of stored-product entomology that need to be considered in planning, implementation, and evaluation of a pest management program. It is based on the review of an extensive database of references and many years of research on stored-product insect problems by the expert authors. The information in this book helps answer consumers’ concern about pesticide residues in food by providing helpful IPM and alternative approaches for pest management. It provides the basic information needed to manage pests with and without the use of chemicals. Managing pests requires a thorough understanding of insect biology, behavior, ecology, sampling, pros and cons of management options, and responses of insects to the various management options. This comprehensive book covers all of these topics, beginning with a discussion of the scope of stored-product entomology. It also provides insight into the diversity of foods and habitats utilized by stored-product insects, the types of economic losses attributable to them, and the ways in which an understanding of their biology can be used to study or manage these insects. Insect mobility, sources of insect infestation, sampling, life history, and population growth are discussed as well, as they play an important role in developing an effective sampling program. In addition, decision aids, the cost of management methods, and the resistance of insects to management methods are covered. For insight into the thought process of choosing treatment options, eight pest management methods are thoroughly described, including a statement of the basic operating principle and background information. For help choosing various chemical and nonchemical methods for diverse situations, the advantages, disadvantages and implementation options for each method are given. Students, extension educators, consultants, food industry sanitarians and managers, legislators, regulators, and insect pest management professionals are sure to find information that will help them to improve pest management.

  • Pediatrics in Systemic Autoimmune Diseases

    • 2 Edición
    • Volumen 11
    • Rolando Cimaz + 1 más
    • Inglés
    Pediatrics in Systemic Autoimmune Diseases, Second Edition, provides a good starting point for physicians and scientists new to the field and for anyone looking for the most up-to-date summary of a particular disease. While many questions are answered, many more are raised for which we do not yet have the answers. The book provides inspiration to readers conducting their own research and helps to answer their questions. The care of children with systemic autoimmune diseases is moving forward at a rapid pace. The systemic autoimmune diseases of childhood have always represented a special problem for the physicians and scientists who care for the affected children and study their diseases. Some conditions, such as Kawasaki disease, are virtually unique to childhood, while systemic lupus erythematosus, progressive systemic sclerosis, and juvenile onset spondyloarthropathie... may be thought of as the early onset of the same disease which is seen in adults. The autoinflammatory disorders appear to be of clear genetic origin, accounting for their frequent discovery in childhood. For many other conditions, such as juvenile dermatomyositis, the relationship between the conditions seen in children and that seen in adults is less certain. This book explores these phenomena, giving users a foundation on which to understand certain diseases.

  • Skin Diseases of Cattle in the Tropics

    A Guide to Diagnosis and Treatment
    • 1 Edición
    • Mohamed Elamin Hamid
    • Inglés
    Skin Diseases of Cattle in the Tropics: A Guide to Diagnosis and Treatment is a clinical and practical guide to help animal scientists, field veterinarians, veterinary students, and technicians make appropriate and differential diagnoses. It features quizzes of clinical cases, along with multiple images of characteristic lesions and laboratory findings of major skin diseases (and diseases with skin manifestations) that are prevalent in tropical areas, notably the Sub-Saharan African countries. This self-learning and easy-to-use instructional guide, a unique offering in the field of animal science and veterinary medicine, provides essential and foundational information about relevant skin conditions that are followed by illustrated flow charts of laboratory diagnoses and summaries of respective diseases. This title makes the subject accessible for practicing veterinarians and animal scientists, and is particularly useful for those who have neither seen nor had the chance to see these diseases in the field or clinics. Such diseases are important not only in the tropics, but may be encountered in many countries in subtropical and temperate zones.

  • The Molecular Nutrition of Amino Acids and Proteins

    A Volume in the Molecular Nutrition Series
    • 1 Edición
    • Dominique Dardevet
    • Inglés
    The Molecular Nutrition of Amino Acids and Proteins provides an in-depth look at the involvement and role of amino acids and proteins in molecular nutrition. Editor Dominique Dardevet has assembled a collection of chapters written by leading researchers and top professors that provide the reader with a comprehensive understanding of amino acids and proteins. The book provides an introduction to the fundamentals of amino acids and proteins as well as the composition of food. It then delves into the molecular biology of the cell and genetic machinery and its function. The Molecular Nutrition of Amino Acids and Proteins also features reference guides for terms and bullet-point summaries, making it readily accessible to novices while still providing the most up-to-date and detailed information that experienced researchers need.

  • Molecular Biological Markers for Toxicology and Risk Assessment

    • 1 Edición
    • Bruce A. Fowler
    • Inglés
    Molecular Biological Markers for Toxicology and Risk Assessment provides an introduction to the exciting field of biomarkers and their use in toxicology and risk assessment. In recent years, new classes of molecular biomarkers capable of detecting early manifestations of ongoing chemical-induced cell injury and cell death have been developed as a result of advances in analytical chemistry, molecular biology, and computational modeling. The interplay between these emergent tools of science has resulted in new insights into initial mechanisms of chemical-induced toxicity and carcinogenicity. Molecular Biological Markers for Toxicology and Risk Assessment guides the reader through a broad range of molecular biological markers, including the "omic" biomarkers, and provides an examination of the various elements in the evolution of these modern tools. It then explores possible ways in which these markers may be applied to advance the field of chemical risk assessment. Since molecular biomarkers and related technologies are inherently complex, the book concludes with a section on risk communication in order that readers may appreciate both the strengths and limitations of molecular biological marker approaches to risk assessment practice.

  • Scallops

    Biology, Ecology, Aquaculture, and Fisheries
    • 3 Edición
    • Volumen 40
    • Sandra E. Shumway + 1 más
    • Inglés
    Scallops: Biology, Ecology, Aquaculture and Fisheries, Third Edition, continues its history as the definitive resource on scallops, covering all facets of scallop biology, including anatomy, taxonomy, physiology, ecology, larval biology, and neurobiology. More than thirty extensive chapters explore both fisheries and aquaculture for all species of scallops in all countries where they are fished or cultured. This treatise has been updated to include the most recent advances in research and the newest developments within the industry. As aquaculture remains one of the fastest-growing animal food-producing sectors, this reference becomes even more vital. It has all the available information on scallops needed to equip researchers to deal with the unique global issues in the field.

  • DNA Repair in Cancer Therapy

    Molecular Targets and Clinical Applications
    • 2 Edición
    • Mark R. Kelley + 1 más
    • Inglés
    DNA Repair and Cancer Therapy: Molecular Targets and Clinical Applications, Second Edition provides a comprehensive and timely reference that focuses on the translational and clinical use of DNA repair as a target area for the development of diagnostic biomarkers and the enhancement of cancer treatment. Experts on DNA repair proteins from all areas of cancer biology research take readers from bench research to new therapeutic approaches. This book provides a detailed discussion of combination therapies, in other words, how the inhibition of repair pathways can be coupled with chemotherapy, radiation, or DNA damaging drugs. Newer areas in this edition include the role of DNA repair in chemotherapy induced peripheral neuropathy, radiation DNA damage, Fanconi anemia cross-link repair, translesion DNA polymerases, BRCA1-BRCA2 pathway for HR and synthetic lethality, and mechanisms of resistance to clinical PARP inhibitors.

  • Genomics, Circuits, and Pathways in Clinical Neuropsychiatry

    • 1 Edición
    • Thomas Lehner + 2 más
    • Inglés
    This foundational work comprehensively examines the current state of the genetics, genomics and brain circuitry of psychiatric and neurological disorders. It consolidates discoveries of specific genes and genomic regions associated with these conditions, the genetic and anatomic architecture of these syndromes, and addresses how recent advances in genomics are leading to a reappraisal of the biology underlying clinical neuroscience. In doing so, it critically examines the promise and limitations of these discoveries toward treatment, and to the interdisciplinary nature of understanding brain and behavior. Coverage includes new discoveries regarding autism, epilepsy, intellectual disability, dementias, movement disorders, language impairment, disorders of attention, schizophrenia, and bipolar disorder. Genomics, Circuits, and Pathways in Clinical Neuropsychiatry focuses on key concepts, challenges, findings, and methods in genetics, genomics, molecular pathways, brain circuitry, and related neurobiology of neurologic and psychiatric disorders.

  • How to Validate a Pharmaceutical Process

    • 1 Edición
    • Steven Ostrove
    • Inglés
    How to Validate a Pharmaceutical Process provides a “how to” approach to developing and implementing a sustainable pharmaceutical process validation program. The latest volume in the Expertise in Pharmaceutical Process Technology Series, this book illustrates the methods and reasoning behind processes and protocols. It also addresses practical problems and offers solutions to qualify and validate a pharmaceutical process. Understanding the “why” is critical to a successful and defensible process validation, making this book an essential research companion for all practitioners engaged in pharmaceutical process validation.

  • Sjogren's Syndrome

    Novel Insights in Pathogenic, Clinical and Therapeutic Aspects
    • 1 Edición
    • Alessia Alunno + 2 más
    • Inglés
    Sjogren's Syndrome: Novel Insights in Pathogenic, Clinical and Therapeutic Aspects provides the reader with an overview of current knowledge about Sjogren's Syndrome. The book summarizes the huge amount of literature concerning related advances in genetic background, pathogenesis, clinical picture, and therapeutic approaches. It integrates basic immunology concepts, clinical aspects, and pharmacological issues. Scientific progress has allowed us to unmask novel pathogenic mechanisms, to perform genome wide studies, and to identify clinical and serological features associated with different disease subsets and, eventually, different disease prognoses. In addition, the increasing knowledge about SS pathogenesis provides the rationale to employ targeted therapies in SS as has already occurred in rheumatoid arthritis and systemic lupus erythematosus.

  • Albumin: Structure, Biosynthesis, Function

    Federation of European Biochemical Societies 11Th Meeting Copenhagen 1977
    • 1 Edición
    • Theodore Peters + 1 más
    • Inglés
    Albumin: Structure, Biosynthesis, Function is a collection of papers from the 11th meeting of the Federation of European Biochemical Societies in Copenhagen in 1977. The book starts with a review of the structure and evolution of serum albumin, the amino acid sequence, and the structure and conformation of albumin. One paper then explains the biosynthesis of proalbumin and the mechanism of its conversion to albumin. Another paper discusses the secretory process of albumin and of other export proteins, which are as follows: synthesis, segregation, intracellular migration, concentration, and discharge to the circulation. The text then presents the generalized binding model, a new method of analysis, in free fatty acid binding to albumin. The book also explains the role of albumin in free fatty acid utilization by the tissues. One paper then describes the property of serum albumin — that it has the ability to bind several different substances of various chemical structures, such as fatty acids, bilirubin, and various exogenous compounds or drugs. The paper then notes the drug interactions resulting from these binding actions of the different compounds. The text will prove a handy reference for the microbiologists, cellular biologists, and researchers in organic chemistry.

  • Art and Human Experience

    The Commonwealth and International Library: Liberal Studies Division
    • 1 Edición
    • Pamela Rydzewski
    • E. F. Candlin + 1 más
    • Inglés
    Art and Human Experience discusses the various art traditions from different time periods and cultural origin. The title details the problems faced by artists, the basic principles of design. The text first tackles the importance of art in human life, and then proceeds to covering various forms of art. Next, the selection deals with the art culture from different time and location. The coverage of the title includes Stone Age art, African, Amerindian, Egyptian, Greek, Roman, Chinese, and European. The last chapter talks about contemporary art design. The book will be of great interest to individuals who have a keen interest in art history.

  • Pharmacology for Student and Pupil Nurses and Students in Associated Professions

    • 2 Edición
    • Bernard R. Jones
    • Inglés
    Pharmacology for Student and Pupil Nurses and Students in Associated Professions is based on lectures that have been updated and presented to nurses in training for the State Registration and State Enrolment Examinations and to Students in Dispensing. This book describes therapies and drug trends in the industry, as well as many types of drugs, their administration, dosage, usage, and effects. Functions of the pertinent human anatomy are included to illustrate the absorption of these drugs. This book includes a section on patient counseling; the use of the International System of Units (SI); and the immune-response process related to specialized fields of treatment. Patient counseling is undertaken for patients who will continue treatment at home. The nurse gives proper advice on the administration of the patient's medicine. SI was adopted to enhance the standardization of the unit of measurement for volume, weight, temperature, and length. This standard includes the use of the terms Celsius, millimole, and joule and the way of writing abbreviations and numbers in the Metric system. The immune-response process deals with the mechanism and related aspects concerning the two groups of cytotoxics, antimitotics and antimetabolites. The side effects of these drugs when used, for example, in chemotherapy, are discussed. This book will prove useful to pharmacists, student pharmacy technicians, professors of pharmacology, practitioners of general medicines, and specialists with interests in drug therapy.

  • Agrarian Development in Peasant Economies

    Some Lessons from Kenya
    • 1 Edición
    • Eric Clayton
    • M. Mcg. Cooper
    • Inglés
    Agrarian Development in Peasant Economies: Some Lessons from Kenya examines agrarian development in peasant, agricultural economies by focusing on Kenya and the lessons that can be learned from its experience. Topics covered include the beginnings of rural progress in Kenya; post-war agricultural policies and developments; the agrarian revolution; and the economics of peasant agriculture. Problems associated with agrarian reform are also discussed. This volume is comprised of seven chapters and begins with a historical background on Kenya's peasant agriculture, paying particular attention to the government's initiatives aimed at increasing agricultural production and controlling soil erosion. The next chapter deals with the country's agricultural policies after World War II, including the implementation of a ten-year development plan and introduction of incentives to improve farming. Subsequent chapters look at the agrarian revolution in Kenya; certain features of peasant agriculture, including indigenous farming systems; the economics of the farm and the agricultural sector; and the policies pursued by the government to achieve agrarian development. The final chapter considers some of the issues affecting agrarian reform, including smallholding and rights of ownership and financing of rural development, in part by taxation. This monograph will be of interest to farmers and agriculturists as well as agricultural and economic policymakers.

  • Snow Leopards

    Biodiversity of the World: Conservation from Genes to Landscapes
    • 1 Edición
    • Inglés
    Snow Leopards: Biodiversity of the World: Conservation from Genes to Landscapes is the only comprehensive work on the biology, behavior, and conservation status of the snow leopard, a species that has long been one of the least studied, and hence poorly understood, of the large cats. Breakthroughs in technologies and methodologies to study this elusive cat have come rapidly, including non-invasive genetics, camera traps, and GPS-satellite collaring. The book begins with chapters on the genetic standing and taxonomy of the snow leopard, followed by chapters on their behavior and ecology. Additional contributions follow on the current and emerging threats to the species, which include longstanding concerns, such as poaching and conflicts with livestock, and new and emerging threats such as mining and climate change. A section on conservation solutions, backed by valuable case studies, starts with an overview of the important role mountain communities play in assuring the snow leopard’s long-term persistence. In addition, chapters on the role of captive snow leopards for the conservation of the species, state-of-the-art techniques and technologies for studying and monitoring snow leopards, status reports from around the region, and future perspectives, such as transboundary conservation initiatives, international conventions (CITES, CMS, etc.), the role of the IUCN Cat Specialist Group and the Snow Leopard Network, and undertakings such as the Global Snow Leopard Forum facilitated by the World Bank are also included.

  • The First Week of Life

    A Survey Under the Joint Auspices of the National Birthday Trust Fund and the Royal College of Obstetricians and Gynaecologists
    • 1 Edición
    • Roma Chamberlain + 2 más
    • Inglés
    British Births 1970, A Survey under the Joint Auspices of the National Birthday Trust Fund and the Royal College of Obstetricians and Gynaecologists, Volume 1: The First Week of Life covers a fresh survey and a national study of all deliveries during a one-week period in 1970. This report is composed of eight chapters, tracing the success of the First Perinatal Mortality Survey done in 1958 to the new British Births survey in 1970, which took place in the week beginning April 5, 1970 in England, Wales, Scotland, and Northern Ireland. Topics analyzed are factors affecting the accuracy of the measurement of birth weight and those affecting the length of gestation. These factors are grouped into social, biological, maternal, and fetal factors that include the precise use of the weighing machines and poor recording. A useful guide throughout the survey is the state of the baby's health. The illnesses prone to affect the baby are also discussed, from extra cranial injuries, hypoglycemia, hypocalcemia, congenital abnormalities, jaundice, and remaining other conditions such as feeding problems. The care of the baby is then discussed, including feeding patterns and the choice of feed. This report concludes with a discussion on stillbirths and deaths occurring in the first-week of life. Because of these surveys, British obstetric and pediatric management is improved, and the disabilities arising before and during birth, and in the early neonatal period, are reduced. This book is suitable for pediatricians, obstetricians and gynecologists, nurses, professors in general medicine, and administrators of public health services.

  • Advances in Agricultural Microbiology

    • 1 Edición
    • N.S. Subba Rao
    • Inglés
    Advances in Agricultural Microbiology is a collection of papers about the progresses in the field of agricultural microbiology. The said papers are contributions of different experts in related fields. The book is divided into three sections. Section A covers topics related to the role of microorganisms in the mobilization of nutrients for plant growth such as the relationship of microbial genetics and biological nitrogen; plant surface microflora and plant nutrition; and developments in grass-bacteria associations. Section B discusses the use of microorganisms in the management of pathogens, pests, and weeds and includes topics such as the microbial control of insect pests; microbial herbicides; and agricultural antibiotics. Section C tackles strategies in bioconversion such as the production of biogas from agricultural wastes; bioconversion of lignocelluloses into protein-rich food and feed; and ethanol fuel from biomass. The text is recommended for biologists and agriculturists who would like to know more about the importance of microorganisms in the field of agriculture.

  • The Ultrastructure of the Animal Cell

    International Series in Pure and Applied Biology, Volume 55
    • 2 Edición
    • L. T. Threadgold
    • G. A. Kerkut
    • Inglés
    The Ultrastructure of the Animal Cell focuses on the ultrastructure of the animal cell, with emphasis on cell chemistry, biochemistry, and physiology. Discussions are organized around the interphase cell and cell division and cover topics ranging from the general structure and molecular models of cell membranes to the ultrastructure of the nucleus and the cytosome. Changes in cell ultrastructure during embryogenesis, differentiation, and secretion are also examined. This monograph is comprised of nine chapters and begins with an introduction to the principles and techniques of electron microscopy. The next section is devoted to the interphase cell and first presents an overview of the animal cell before considering the ultrastructure of the nucleus and the cytosome, with particular reference to the plasma membrane and associated structures; the hyaloplasm; endoplasmic reticulum; the Golgi complex; and mitochondria. The changes that take place in the ultrastructure of the cell during embryogenesis, differentiation, and secretion are also analyzed. The last section deals with cell division and the ultrastructure of the dividing cell. This text will be a useful resource for cell biologists, biochemists, and physiologists, as well as students and teachers of biology, biochemistry, and physiology.

  • Current Concepts in Kinin Research

    Proceedings of the Satellite Symposium of the 7th International Congress of Pharmacology, Paris, 22 July 1978
    • 1 Edición
    • Gert L. Haberland + 1 más
    • Inglés
    Current Concepts in Kinin Research contains the proceedings of the Satellite Symposium of the 7th International Congress of Pharmacology held in Paris on July 22, 1978. The book is organized into four parts. Part I explains the functions and mechanisms of the kinin system. Part II focuses on kallikreins and the methods of their determination. Part III describes the intrinsic blood clotting and plasma kinin formation. The last part deals with the characterization of plasma kininogens.

  • Photochemistry of Proteins and Nucleic Acids

    International Series of Monographs on Pure and Applied Biology, Volume 22
    • 1 Edición
    • A. D. McLaren + 1 más
    • P. Alexander + 1 más
    • Inglés
    Photochemistry of Proteins and Nucleic Acids focuses on the effects of ultraviolet and visible radiations on proteins and nucleic acids. The book first discusses some principles of photochemistry, including the laws of photochemistry and factors influencing photochemical reactions in solutions. The text describes absorption and luminescence spectra of nucleoproteins and their components, including principal absorbing groups in proteins, nucleic acids, and nucleoproteins. The selection also highlights the action of ultraviolet light on proteins; photochemical and photosensitized inactivation of enzymes; and the photochemistry of purine and pyrimidine derivatives. The text also discusses nucleic acids and oligo- and polynucleotides. Topics include photochemical degradation of nucleic acid; kinetics of biological inactivation of nucleic acids; nucleoproteins; and reversibility of nucleic acid photolysis. The book also encompasses the inactivation of viruses, including inactivation studies with a plant virus, bacteriophages, and photochemically produced vaccines. The text also presents some problems in photobiology and some techniques in photochemistry. The text is a good source of information for readers interested in the study of proteins and nucleic acids.

  • The Release of Catecholamines from Adrenergic Neurons

    • 1 Edición
    • David M. Paton
    • Inglés
    The Release of Catecholamines from Adrenergic Neurons focuses on the processes involved in determining the release of catecholamines from neurons, noting the influence of alcohols, analgesics, and acids in the release. The selection first discusses biochemical and ultrastructural studies of the mechanism of release, as well as release of constituents of noradrenergic vesicles upon nerve stimulation; constituents of noradrenergic vesicles; and mechanism of release. The book then takes a look at the role of calcium in catecholamine release from adrenergic nerve terminals and presynaptic adrenoceptors and regulation of release. Topics include calcium-dependent versus calcium-independent noradrenaline release; differences between the presynaptic and postsynaptic alpha-adrenoceptors; and influence of neuronal uptake of noradrenaline on the negative feedback mechanism mediated by presynaptic alpha-adrenoceptors. The publication reviews presynaptic muscarine receptors and inhibition of release, including muscarinic inhibition of noradrenaline release evoked by electrical stimulation of sympathetic nerves; effect of muscarinic agonists on noradrenaline releasing procedures independent of calcium ions; and possible physiological and pharmacological significance of the muscarinic inhibitory mechanism. The text also ponders on the role of prostaglandins, cyclic adenosine monophate, analgesics, peptides, acids, anesthetics, and alcohols in the release. The selection is a dependable reference for readers interested in the study of the release of catecholamines from adrenergic neurons.

  • Human Dentofacial Growth

    • 1 Edición
    • Denys H. Goose + 1 más
    • Inglés
    Human Dentofacial Growth addresses the study of development and growth of the craniofacial region, which is required as a background for orthodontics and pedodontics. Designed as a reference book for dental students, the book discusses and stresses the relevance of clinical problems. Starting with a background of human growth – prenatal, postnatal, and the factors affecting growth, the book then shifts attention to the bone formation throughout the embryonic, fetal, and post-natal life. The bone development, structure, and growth are also explained. The growth of the craniofacial region is also examined, and a description of the mandible follows. Illustrations accompany this description and the growth process of the mandible is given in more detail. Emphasis is given to the temporomandibular joint between the condylar process of the mandible and the squamous temporal bone of the cranium. Cephalometric techniques in orthodontic assessment and treatment management and monitoring are described. Cephalometric approaches are also included in analyzing facial growth. An important part of dentofacial development and growth is the development and structure of the teeth and their supporting structures. The role of ectomesenchyme in tooth development and more descriptive details on the dentine, enamel, and the periodontium are given. The formation of the dental arch is then examined, including the mechanism of tooth eruption, reasons for differences in tooth number, and the interaction between the teeth and dental arches. Students of dentistry and orthodontics, cosmetic dentists, oral surgeons, dental hygienists, and professors interested in craniofacial growth will find this book valuable.

  • Genes and Evolution

    • 1 Edición
    • Volumen 119
    • Inglés
    Genes and Evolution, the latest volume in the Current Topics in Developmental Biology series, covers genes and evolution, with contributions from an international board of authors. The chapters provide a comprehensive set of reviews covering such topics as genes and plant domestication, gene networks, phenotypic loss in vertebrates, reproducible evolutionary changes, and epithelial tissue.

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