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Elsevier

Libros en Ciencias de la Vida

  • Kidney Development, Disease, Repair and Regeneration

    • 1 Edición
    • Melissa Helen Little
    • Inglés
    Kidney Development, Disease, Repair and Regeneration focuses on the molecular and cellular basis of kidney development, exploring the origins of kidney lineages, the development of kidney tissue subcompartments, as well as the genetic and environmental regulation of kidney development. Special coverage is given to kidney stem cells and possible steps towards kidney repair and regeneration. Emphasis is placed on the fetal origins of postnatal renal disease and our current understanding of the molecular basis of damage and repair. Biomedical researchers across experimental nephrology and developmental biology will find this a key reference for learning how the underlying developmental mechanisms of the kidney will lead to greater advances in regenerative medicine within nephrology.

  • Molecular Biology of Eye Disease

    • 1 Edición
    • Volumen 134
    • Inglés
    This volume of Progress in Molecular Biology and Translational Science focuses on the molecular biology of eye disease.

  • Orbit and Neuro-ophthalmic Imaging, An Issue of Neuroimaging Clinics

    • 1 Edición
    • Volumen 25-3
    • Juan E. Gutierrez
    • Inglés
    Orbit and Neuro-ophthalmic Imaging is explored in this important Neuroimaging Clinics issue. Articles include: Imaging indication, protocols, anatomy, and pitfalls; Orbital ultrasonography and optical coherence tomography – what radiologists need to know; Advanced imaging techniques for the retina and visual pathway; Imaging of optic neuropathy and chiasmatic disorder; Imaging of post-chiasmatic disorder and higher cortical visual dysfunction; Imaging of diseases of the ocular motor pathway; Imaging of orbital trauma and emergent non-traumatic conditions; Imaging of ocular prosthesis and orbital reconstruction flaps; Imaging of pediatric ophthalmologic conditions; and more!

  • RNA Modification

    • 1 Edición
    • Volumen 560
    • Inglés
    RNA Modification provides a useful examination of the science and its role in biological regulation, the current frontier of life science research, and includes various RNA modications and their role in gene expression. It represents the most up-to-date knowledge and protocols available today.

  • Environmental Mycology in Public Health

    Fungi and Mycotoxins Risk Assessment and Management
    • 1 Edición
    • Carla Viegas + 5 más
    • Inglés
    Environmental Mycology in Public Health: Fungi and Mycotoxins Risk Assessment and Management provides the most updated information on fungi, an essential element in the survival of our global ecology that can also pose a significant threat to the health of occupants when they are present in buildings. As the exposure to fungi in homes is a significant risk factor for a number of respiratory symptoms, including allergies and hypersensitivity pneumonitis, this book presents information on fungi and their disease agents, important aspects of exposure assessment, and their impacts on health. This book answers the hard questions, including, "How does one detect and measure the presence of indoor fungi?" and "What is an acceptable level of indoor fungi?" It then examines how we relate this information to human health problems.

  • Acrylamide in Food

    Analysis, Content and Potential Health Effects
    • 1 Edición
    • Vural Gokmen
    • Inglés
    Acrylamide in Food: Analysis, Content and Potential Health Effects provides the recent analytical methodologies for acrylamide detection, up-to-date information about its occurrence in various foods (such as bakery products, fried potato products, coffee, battered products, water, table olives etc.), and its interaction mechanisms and health effects. The book is designed for food scientists, technologists, toxicologists, and food industry workers, providing an invaluable industrial reference book that is also ideal for academic libraries that cover the domains of food production or food science. As the World Health Organization has declared that acrylamide represents a potential health risk, there has been, in recent years, an increase in material on the formation and presence of acrylamide in different foods. This book compiles and synthesizes that information in a single source, thus enabling those in one discipline to become familiar with the concepts and applications in other disciplines of food science.

  • Advances in Planar Lipid Bilayers and Liposomes

    • 1 Edición
    • Volumen 22
    • Inglés
    The Elsevier book-series Advances in Planar Lipid Bilayers and Liposomes, provides a global platform for a broad community of experimental and theoretical researchers studying cell membranes, lipid model membranes and lipid self-assemblies from the micro- to the nanoscale. Planar lipid bilayers are widely studied due to their ubiquity in nature and find their application in the formulation of biomimetic model membranes and in the design of artificial dispersion of liposomes. Moreover, lipids self-assemble into a wide range of other structures including micelles and the liquid crystalline hexagonal and cubic phases. Consensus has been reached that curved membrane phases do play an important role in nature as well, especially in dynamic processes such as vesicles fusion and cell communication. Self-assembled lipid structures have enormous potential as dynamic materials ranging from artificial lipid membranes to cell membranes, from biosensing to controlled drug delivery, from pharmaceutical formulations to novel food products to mention a few. An assortment of chapters in APLBL represents both an original research as well as comprehensives reviews written by world leading experts and young researchers.

  • Marine Mammals of the World

    A Comprehensive Guide to Their Identification
    • 2 Edición
    • Marc A. Webber + 2 más
    • Inglés
    This new edition of Marine Mammals of the World describes and illustrates newly discovered and rarely photographed species, making it the most comprehensive and up-to-date identification guide available. This edition continues to meet the research-focused needs of marine biologists and conservation biologists by providing a tremendous influx of new photos, taking advantage of advances in digital and auto-focusing photography, and the emergence of marine mammal studies and "whalewatching" around the world. The book encompasses cetacean, pinniped, and sirenian species, as well as extinct species, and describes basic biology and taxonomic groupings of marine mammals.

  • Cancer Treatment and the Ovary

    Clinical and Laboratory Analysis of Ovarian Toxicity
    • 1 Edición
    • Richard A Anderson + 1 más
    • Inglés
    Cancer Treatment and the Ovary: Clinical and Laboratory Analysis of Ovarian Toxicity provides the reader with a basic understanding on how the ovary is adversely impacted by cancer treatment, an essential foundational knowledge for this rapidly-developing field. The book describes both the clinical and laboratory approaches to discovering the potentially adverse effects of cancer treatment on the ovary, also laying out possible preventative approaches and future directions for the field. Clinicians working in the field of reproductive biology and oncology will find an essential reference that provides the necessary tools to assess the reproductive toxicological effects of cancer treatments.

  • Feeding Everyone No Matter What

    Managing Food Security After Global Catastrophe
    • 1 Edición
    • David Denkenberger + 1 más
    • Inglés
    NB: Due to the inadvertent assignment of a previously used ISBN, this book was originally published under an incorrect identifying number. The book has now been given its own unique ISBN and is otherwise identical in every way to the original publication. Feeding Everyone No Matter What presents a scientific approach to the practicalities of planning for long-term interruption to food production. The primary historic solution developed over the last several decades is increased food storage. However, storing up enough food to feed everyone would take a significant amount of time and would increase the price of food, killing additional people due to inadequate global access to affordable food. Humanity is far from doomed, however, in these situations - there are solutions. This book provides an order of magnitude technical analysis comparing caloric requirements of all humans for five years with conversion of existing vegetation and fossil fuels to edible food. It presents mechanisms for global-scale conversion including: natural gas-digesting bacteria, extracting food from leaves, and conversion of fiber by enzymes, mushroom or bacteria growth, or a two-step process involving partial decomposition of fiber by fungi and/or bacteria and feeding them to animals such as beetles, ruminants (cows, deer, etc), rats and chickens. It includes an analysis to determine the ramp rates for each option and the results show that careful planning and global cooperation could ensure the bulk of humanity and biodiversity could be maintained in even in the most extreme circumstances.

  • Evolution of Vulnerability

    Implications for Sex Differences in Health and Development
    • 1 Edición
    • David C. Geary
    • Inglés
    Biologists have known for decades that many traits involved in competition for mates or other resources and that influence mate choice are exaggerated, and their expression is influenced by the individuals’ ability to tolerate a variety of environmental and social stressors. Evolution of Vulnerability applies this concept of heightened sensitivity to humans for a host of physical, social, psychological, cognitive, and brain traits. By reframing the issue entirely, renowned evolutionary psychologist David C. Geary demonstrates this principle can be used to identify children, adolescents, or populations at risk for poor long-term outcomes and identify specific traits in each sex and at different points in development that are most easily disrupted by exposure to stressors. Evolution of Vulnerability begins by reviewing the expansive literature on traits predicted to show sex-specific sensitivity to environmental and social stressors, and details the implications for better assessing and understanding the consequences of exposure to these stressors. Next, the book reviews sexual selection—mate competition and choice—and the mechanisms involved in the evolution of condition dependent traits and the stressors that can undermine their development and expression, such as poor early nutrition and health, parasites, social stress, and exposure to man-made toxins. Then it reviews condition dependent traits (physical, behavioral, cognitive, and brain) in birds, fish, insects, and mammals to demonstrate the ubiquity of these traits in nature. The focus then turns to humans and covers sex-specific vulnerabilities in children and adults for physical traits, social behavior, psychological wellbeing, and brain and cognitive traits. The sensitivity of these traits is related to exposure to parasites, poor nutrition, social maltreatment, environmental toxins, chemotherapy, and Alzheimer’s disease, among others. The book concludes with an implications chapter that outlines how to better assess vulnerabilities in children and adults and how to more fully understand how, why, and when in development some types of environmental and social stressors are particularly harmful to humans.

  • Advances in Clinical Chemistry

    • 1 Edición
    • Volumen 70
    • Inglés
    Volume 70 in the internationally acclaimed Advances in Clinical Chemistry contains chapters authored by world renowned clinical laboratory scientists, physicians and research scientists. The serial provides the latest and most up-to-date technologies related to the field of clinical chemistry and is the benchmark for novel analytical approaches in the clinical laboratory.

  • Immunotherapy of Cancer

    • 1 Edición
    • Volumen 128
    • Inglés
    Immunotherapy of Cancer provides information on cancer research related to inflammation and immunity, containing outstanding reviews by experts in the field. It is suitable for researchers and students who have an interest in cancer immunobiology.

  • Biofluid Mechanics

    An Introduction to Fluid Mechanics, Macrocirculation, and Microcirculation
    • 2 Edición
    • David Rubenstein + 2 más
    • Inglés
    Biofluid Mechanics: An Introduction to Fluid Mechanics, Macrocirculation, and Microcirculation shows how fluid mechanics principles can be applied not only to blood circulation, but also to air flow through the lungs, joint lubrication, intraocular fluid movement, renal transport among other specialty circulations. This new second edition increases the breadth and depth of the original by expanding chapters to cover additional biofluid mechanics principles, disease criteria, and medical management of disease, with supporting discussions of the relevance and importance of current research. Calculations related both to the disease and the material covered in the chapter are also now provided.

  • Advances in Agronomy

    • 1 Edición
    • Volumen 133
    • Inglés
    Advances in Agronomy continues to be recognized as a leading reference and a first-rate source for the latest research in agronomy. Each volume contains an eclectic group of reviews by leading scientists throughout the world. As always, the subjects covered are varied and exemplary of the myriad of subject matter dealt with by this long-running serial.

  • Improving and Tailoring Enzymes for Food Quality and Functionality

    • 1 Edición
    • Rickey Y. Yada
    • Inglés
    Improving and Tailoring Enzymes for Food Quality and Functionality provides readers with the latest information on enzymes, a biological processing tool that offers the food industry a unique means to control and tailor specific food properties. The book explores new techniques in the production, engineering, and application of enzymes, covering sourcing, isolation, and production of enzymes for food applications. In addition, chapters include detailed discussions of enzyme processing, analytical and diagnostic applications of enzymes in the food industry, and enzyme applications in specific food commodities.

  • Aquatic Functional Biodiversity

    An Ecological and Evolutionary Perspective
    • 1 Edición
    • Andrea Belgrano + 2 más
    • Inglés
    Aquatic Functional Biodiversity: An Ecological and Evolutionary Perspective provides a general conceptual framework by some of the most prominent investigators in the field for how to link eco-evolutionary approaches with functional diversity to understand and conserve the provisioning of ecosystem services in aquatic systems. Rather than producing another methodological book, the editors and authors primarily concentrate on defining common grounds, connecting conceptual frameworks and providing examples by a more detailed discussion of a few empirical studies and projects, which illustrate key ideas and an outline of potential future directions and challenges that are expected in this interdisciplinary research field. Recent years have seen an explosion of interest in using network approaches to disentangle the relationship between biodiversity, community structure and functioning. Novel methods for model construction are being developed constantly, and modern methods allow for the inclusion of almost any type of explanatory variable that can be correlated either with biodiversity or ecosystem functioning. As a result these models have been widely used in ecology, conservation and eco-evolutionary biology. Nevertheless, there remains a considerable gap on how well these approaches are feasible to understand the mechanisms on how biodiversity constrains the provisioning of ecosystem services.

  • Biochemistry of Lipids, Lipoproteins and Membranes

    • 6 Edición
    • Neale Ridgway + 1 más
    • Inglés
    Biochemistry of Lipids: Lipoproteins and Membranes, Volume Six, contains concise chapters that cover a wide spectrum of topics in the field of lipid biochemistry and cell biology. It provides an important bridge between broad-based biochemistry textbooks and more technical research publications, offering cohesive, foundational information. It is a valuable tool for advanced graduate students and researchers who are interested in exploring lipid biology in more detail, and includes overviews of lipid biology in both prokaryotes and eukaryotes, while also providing fundamental background on the subsequent descriptions of fatty acid synthesis, desaturation and elongation, and the pathways that lead the synthesis of complex phospholipids, sphingolipids, and their structural variants. Also covered are sections on how bioactive lipids are involved in cell signaling with an emphasis on disease implications and pathological consequences.

  • Guide to Cell Therapy GxP

    Quality Standards in the Development of Cell-Based Medicines in Non-pharmaceutical Environments
    • 1 Edición
    • Joaquim Vives + 1 más
    • Inglés
    Guide to Cell Therapy GxP is a practical guide to the implementation of quality assurance systems for the successful performance of all cell-based clinical trials. The book covers all information that needs to be included in investigational medicinal product dossier (IMPD), the launching point for any clinical investigation, and beyond. Guide to Cell Therapy GxP bridges a knowledge gap with the inclusion of examples of design of GLP-compliant preclinical studies; design of bioprocesses for autologous/allogenei... therapies; and instruction on how to implement GLP/GMP standards in centers accredited with other quality assurance standards. Guide to Cell Therapy GxP is an essential resource for scientists and researchers in hospitals, transfusion centers, tissue banks, and other research institutes who may not be familiar with the good scientific practice regulations that were originally designed for product development in corporate environments. This book is also a thorough resource for PhD students, Post-docs, Principal Investigators, Quality Assurance Units, and Government Inspectors who want to learn more about how quality standards are implemented in public institutions developing cell-based products.

  • Inmunoterapia del cáncer. Realidades y perspectivas

    Sociedad Española de Inmunología
    • 1 Edición
    • Manuel Juan Otero + 1 más
    • Español
    El objetivo de esta serie de monografías, avaladas por la Sociedad Española de Inmunología (SEI), es presentar diversos temas vinculados a la inmunología clínica con un enfoque multidisciplinar que permita su utilización por parte de diversos especialistas clínicos. Aborda diversos aspectos del presente y el futuro de los tratamientos inmunooncológicos, opciones terapéuticas que ya son realidad en algunos casos y en otros abren una amplia variedad de opciones de gran potencialidad antitumoral. La obra incluye desde anticuerpos monoclonales hasta la inmunoterapia celular adoptiva con los receptores antigénicos quiméricos (CAR), pasando por las inducciones con vacunas o con células dendrítica. Esta obra va dirigida a especialistas de muy diversa índole entre los que se encuentran nefrólogos, urólogos, cirujanos, cardiólogos, oncólogos, alergólogos, gastroenterólogos, internistas, hematólogos, reumatólogos, pediatras, neumólogos, médicos de familia y todos aquellos involucrados en alguno de los procesos en los que participe el sistema inmunológico.

  • Basics in Human Evolution

    • 1 Edición
    • Michael P Muehlenbein
    • Inglés
    Basics in Human Evolution offers a broad view of evolutionary biology and medicine. The book is written for a non-expert audience, providing accessible and convenient content that will appeal to numerous readers across the interdisciplinary field. From evolutionary theory, to cultural evolution, this book fills gaps in the readers’ knowledge from various backgrounds and introduces them to thought leaders in human evolution research.

  • Six Chemicals That Changed Agriculture

    • 1 Edición
    • Robert L Zimdahl
    • Inglés
    Six Chemicals That Changed Agriculture is a scientific look at how the chemicals used in today's food production were developed, evaluated, and came to be in wide-spread use. From fertilizers to pest management, antibiotics to DNA, chemicals have transformed the way our food is grown, protected, and processed. Agriculture is the world's most important environment interaction, the essential human activity, and an increasingly controversial activity because of its use and presumed misuse of chemistry. The major characteristics of US agriculture for at least the last six decades have been rising productivity, declining number of mid-size farms, increasing farm size, an increasing percentage of farm production on fewer, large farms, increasing dependence of chemical technology and more developmental research being done by the agricultural chemical industry rather than by independent land-grant universities. Another equally important feature of modern agriculture is wide-spread suspicion of its technology by the public. The book will recount examples of this suspicion related to specific chemicals and present the essence of the suspicion and its results.

  • Wood Composites

    • 1 Edición
    • Martin P Ansell
    • Inglés
    Recent progress in enhancing and refining the performance and properties of wood composites by chemical and thermal modification and the application of smart multi-functional coatings have made them a particular area of interest for researchers. Wood Composites comprehensively reviews the whole field of wood composites, with particular focus on their materials, applications and engineering and scientific advances, including solutions inspired biomimetrically by the structure of wood and wood composites. Part One covers the materials used for wood composites and examines wood microstructure, and wood processing and adhesives for wood composites. Part Two explores the many applications of wood composites, for example plywood, fibreboard, chipboard, glulam, cross-laminated timber, I-beams and wood-polymer composites. The final part investigates advances in wood composites and looks at the preservation and modification of wood composites, environmental impacts and legislative obligations, nano-coatings and plasma treatment, biomimetic composite materials, the integration of wood composites with other materials and carbonized and mineralized wood composites.

  • Cytochrome P450 Function and Pharmacological Roles in Inflammation and Cancer

    • 1 Edición
    • Volumen 74
    • Inglés
    Cytochrome P450 Function and Pharmacological Roles in Inflammation and Cancer, the latest volume in the Advances in Pharmacology series, presents not only the function of cytochrome P450 but also its pharmacological roles in inflammation and cancer.

  • Modern Applications of Plant Biotechnology in Pharmaceutical Sciences

    • 1 Edición
    • Saurabh Bhatia + 3 más
    • Inglés
    Modern Applications of Plant Biotechnology in Pharmaceutical Sciences explores advanced techniques in plant biotechnology, their applications to pharmaceutical sciences, and how these methods can lead to more effective, safe, and affordable drugs. The book covers modern approaches in a practical, step-by-step manner, and includes illustrations, examples, and case studies to enhance understanding. Key topics include plant-made pharmaceuticals, classical and non-classical techniques for secondary metabolite production in plant cell culture and their relevance to pharmaceutical science, edible vaccines, novel delivery systems for plant-based products, international industry regulatory guidelines, and more. Readers will find the book to be a comprehensive and valuable resource for the study of modern plant biotechnology approaches and their pharmaceutical applications.

  • Biomimetic Technologies

    Principles and Applications
    • 1 Edición
    • Trung Dung Ngo
    • Inglés
    Biomimetic engineering takes the principles of biological organisms and copies, mimics or adapts these in the design and development of new materials and technologies. Biomimetic Technologies reviews the key materials and processes involved in this groundbreaking field, supporting theoretical background by outlining a range of applications. Beginning with an overview of the key principles and materials associated with biomimetic technologies in Part One, the book goes on to explore biomimetic sensors in more detail in Part Two, with bio-inspired tactile, hair-based, gas-sensing and sonar systems all reviewed. Biomimetic actuators are then the focus of Part Three, with vision systems, tissue growth and muscles all discussed. Finally, a wide range of applications are investigated in Part Four, where biomimetic technology and artificial intelligence are reviewed for such uses as bio-inspired climbing robots and multi-robot systems, microrobots with CMOS IC neural networks locomotion control, central pattern generators (CPG’s) and biologically inspired antenna arrays.

  • Essential Clinically Applied Anatomy of the Peripheral Nervous System in the Limbs

    • 1 Edición
    • Paul Rea
    • Inglés
    Essential Clinically Applied Anatomy of the Peripheral Nervous System in the Limbs is designed to combine the salient points of the anatomy of the PNS with typical pathologies affecting the nerves of the upper and lower limbs. The book is a quick reference guide for those studying and treating neuromuscular disease such as neurologists, neurosurgeons, neuroradiologists, and clinical neurophysiologists. Readers will find easy-to-access facts about the anatomy of the nerves in the limbs, coupled with clinically applied scenarios relevant to that area being discussed, as well as clinical findings on examination. The book's purpose is to provide the reader with a succinct presentation of the relevant anatomy of the PNS in the limbs and how it is directly applicable to day-to-day clinical scenarios. It presents the reader with an easily accessible format to clinically applied PNS anatomy that is perfect for quick reference. Chapters review the nerves of the upper and lower limbs, and the origins, course, distribution and relevant pathologies affecting each. These pathologies present typical injuries to the nerves of the PNS, as well as clinical findings on examination and treatments.

  • Nanotechnology-Enhanced Orthopedic Materials

    Fabrications, Applications and Future Trends
    • 1 Edición
    • Lei Yang
    • Inglés
    Nanotechnology-Enhan... Orthopedic Materials provides the latest information on the emergence and rapid development of nanotechnology and the ways it has impacted almost every aspect of biomedical engineering. This book provides readers with a comprehensive overview of the field, focusing on the fabrication and applications of these materials, presenting updated, practical, and systematic knowledge on the synthesis, processing, and modification of nanomaterials, along with the rationale and methodology of applying such materials for orthopedic purposes. Topics covered include a wide range of orthopedic material formulations, such as ceramics, metals, polymers, biomolecules, and self-assemblies. Final sections explore applications and future trends in nanotechnology-enhan... orthopedic materials.

  • Essentials of 3D Biofabrication and Translation

    • 1 Edición
    • Anthony Atala + 1 más
    • Inglés
    Essentials of 3D Biofabrication and Translation discusses the techniques that are making bioprinting a viable alternative in regenerative medicine. The book runs the gamut of topics related to the subject, including hydrogels and polymers, nanotechnology, toxicity testing, and drug screening platforms, also introducing current applications in the cardiac, skeletal, and nervous systems, and organ construction. Leaders in clinical medicine and translational science provide a global perspective of the transformative nature of this field, including the use of cells, biomaterials, and macromolecules to create basic building blocks of tissues and organs, all of which are driving the field of biofabrication to transform regenerative medicine.

  • Advances in Microbial Physiology

    • 1 Edición
    • Volumen 66
    • Inglés
    This volume of Advances in Microbial Physiology continues the long tradition of topical and important reviews in microbiology

  • Shoulder and Elbow Trauma and its Complications

    Volume 1: The Shoulder
    • 1 Edición
    • Michael Greiwe
    • Inglés
    Traumatic injuries to the shoulder remain a problem encountered by young and old alike. Trauma surgeons and shoulder and elbow specialists are called upon daily to improve the quality of life of injured individuals by restoring function, decreasing pain and returning individuals to their previous occupations and places in society. Such treatment provides both humanitarian and economic impact. Only recently have techniques and technology allowed surgeons to restore lives to such a degree following these injuries. Still, shoulder and elbow trauma remains a vexing problem for patients and surgeons alike. Many injuries result in lost work and serious debility including lack of function, post-traumatic arthritis and pain. This important textbook provides a systematic and comprehensive guide to the different types of shoulder trauma and the management of its associated complications. In Part One, the focus is on the most common types of shoulder trauma, with chapters covering anterior instability, traumatic rotator cuff tears, fractures, joint injuries and the floating shoulder and includes sections on the most common complications befalling each injury. Part II then reviews the management of the most common complications. Chapters include detailed analyses of persistent anterior shoulder instability, several forms of nonunion and malunion, failed acromioclavicular joint reconstruction, post-traumatic arthropathy and traumatic osteonecrosis, and failed arthroplasty for fracture.

  • Chinmedomics

    The Integration of Serum Pharmacochemistry and Metabolomics to Elucidate the Scientific Value of Traditional Chinese Medicine
    • 1 Edición
    • Xijun Wang + 2 más
    • Inglés
    Chinmedomics: The Integration of Serum Pharmacochemistry and Metabolomics to Elucidate the Scientific Value of Traditional Chinese Medicine uses new experimental techniques and research to open doors in drug discovery and development related to traditional Chinese medicine (TCM). This book features a unique approach that combines chemometric analysis with metabolomics studies to illuminate significant changes that have occurred in syndrome states while simultaneously analyzing the efficacy of chemical ingredients in herbal medicines. Chapters provide cutting-edge information on traditional medicine, analytical technology, natural products, metabolomics, bioinformatics and their applications. This book provides a valuable resource for pharmacologists, pharmaceutical scientists, medicinal plant researchers, pharmacognosists and chemists working with TCM and highlights ways to further research and advances in this area in the future.

  • Nonclinical Assessment of Abuse Potential for New Pharmaceuticals

    • 1 Edición
    • Carrie Markgraf + 2 más
    • Inglés
    Nonclinical Assessment of Abuse Potential for New Pharmaceuticals offers a complete reference on the current international regulatory guidelines and details best practice methodology for the three standard animal models used to evaluate abuse potential: physical dependence, self-administration and drug discrimination. This book also includes chapters on alternative models and examples of when you should use these alternatives. Case histories are provided at the end of the book to show how the data generated from the animal models play a pivitol role in the submission package for a new drug. By incorporating all of this information into one book, Nonclinical Assessment of Abuse Potential for New Pharmaceuticals is your single resource for everything you need to know to understand and implement the assessment of abuse liability.

  • Logan Turner's Diseases of the Nose, Throat and Ear

    • 6 Edición
    • John P. Stewart
    • Inglés
    Logan Turner's Diseases of the Nose, Throat, and Ear, Sixth Edition elaborates the treatment of malignant disease of the larynx and ear. This book covers relevant topics, including sulfa drugs and antibiotics, peroral endoscopy, and affections of the paranasal sinuses. Organized into 43 chapters, this edition begins with an overview of the functions of the larynx that vary in significance, including protection of the lungs, phonation, fixation of the chest, and a channel for respiration. This text then explores the various processes of examination of the cavities of the nose. Other chapters consider the deformity called saddle nose, which consists in a sinking-in of the dorsum of the nose. This book discusses as well the examination of chronic catarrh of the middle ear. The final chapter deals with the congenital defects of the labyrinth, which are responsible for the condition known as sporadic congenital deaf-mutism. This book is a valuable resource for clinicians.

  • Centrosome and Centriole

    • 1 Edición
    • Volumen 129
    • Inglés
    This new volume of Methods in Cell Biology looks at methods for analyzing centrosomes and centrioles. Chapters cover such topics as methods to analyze centrosomes, centriole biogenesis and function in multi-ciliated cells, laser manipulation of centrosomes or CLEM, analysis of centrosomes in human cancers and tissues, proximity interaction techniques to study centrosomes, and genome engineering for creating conditional alleles in human cells.

  • Food Safety

    Emerging Issues, Technologies and Systems
    • 1 Edición
    • Steven Ricke + 2 más
    • Inglés
    Food Safety: Emerging Issues, Technologies and Systems offers a systems approach to learning how to understand and address some of the major complex issues that have emerged in the food industry. The book is broad in coverage and provides a foundation for a practical understanding in food safety initiatives and safety rules, how to deal with whole-chain traceability issues, handling complex computer systems and data, foodborne pathogen detection, production and processing compliance issues, safety education, and more. Recent scientific industry developments are written by experts in the field and explained in a manner to improve awareness, education and communication of these issues.

  • Plant Transcription Factors

    Evolutionary, Structural and Functional Aspects
    • 1 Edición
    • Daniel H Gonzalez
    • Inglés
    Plant Transcription Factors: Evolutionary, Structural and Functional Aspects is the only publication that provides a comprehensive compilation of plant transcription factor families and their complex roles in plant biology. While the majority of information about transcription factors is based on mammalian systems, this publication discusses plant transcription factors, including the important aspects and unifying themes to understanding transcription factors and the important roles of particular families in specific processes.

  • Laboratory Animal Medicine

    • 3 Edición
    • James G. Fox + 4 más
    • Inglés
    Laboratory Animal Medicine, Third Edition, is a fully revised publication from the American College of Laboratory Medicine’s acclaimed blue book series. It presents an up-to-date volume that offers the most thorough coverage of the biology, health, and care of laboratory animals. The book is organized by species, with new inclusions of chinchillas, birds, and program and employee management, and is written and edited by known experts in the fields. Users will find gold-standard guidance on the study of laboratory animal science, as well as valuable information that applies across all of the biological and biomedical sciences that work with animals.

  • Food Waste Recovery

    Processing Technologies and Industrial Techniques
    • 1 Edición
    • Charis M. Galanakis
    • Inglés
    Food Waste Recovery: Processing Technologies and Industrial Techniques acts as a guide to recover valuable components of food by-products and recycle them inside the food chain, in an economic and sustainable way. The book investigates all the relevant recovery issues and compares different techniques to help you advance your research and develop new applications. Strong coverage of the different technologies is included, while keeping a balance between the characteristics of current conventional and emerging technologies. This is an essential reference for research outcomes.

  • Biosensors and Bioelectronics

    • 1 Edición
    • Chandran Karunakaran + 2 más
    • Inglés
    Biosensors and Bioelectronics presents the rapidly evolving methodologies that are relevant to biosensors and bioelectronics fabrication and characterization. The book provides a comprehensive understanding of biosensor functionality, and is an interdisciplinary reference that includes a range of interwoven contributing subjects, including electrochemistry, nanoparticles, and conducting polymers. Authored by a team of bioinstrumentation experts, this book serves as a blueprint for performing advanced fabrication and characterization of sensor systems—arming readers with an application-based reference that enriches the implementation of the most advanced technologies in the field.

  • Epigenetic Cancer Therapy

    • 1 Edición
    • Steven Gray
    • Inglés
    Epigenetic Cancer Therapy unites issues central to a translational audience actively seeking to understand the topic. It is ideal for cancer specialists, including oncologists and clinicians, but also provides valuable information for researchers, academics, students, governments, and decision-makers in the healthcare sector. The text covers the basic background of the epigenome, aberrant epigenetics, and its potential as a target for cancer therapy, and includes individual chapters on the state of epigenome knowledge in specific cancers (including lung, breast, prostate, liver). The book encompasses both large-scale intergovernmental initiatives as well as recent findings across cancer stem cells, rational drug design, clinical trials, and chemopreventative strategies. As a whole, the work articulates and raises the profile of epigenetics as a therapeutic option in the future management of cancer.

  • Land Plants - Trees

    • 1 Edición
    • Volumen 74
    • Inglés
    Advances in Botanical Research publishes in-depth and up-to-date reviews on a wide range of topics in plant sciences. Currently in its 74th volume, the series features several reviews by recognized experts on all aspects of plant genetics, biochemistry, cell biology, molecular biology, physiology, and ecology. This volume features reviews on the advances in knowledge for the main traits important in fruit trees and forest trees, the advances in tools and resources for genetics and genomics in these species, and the knowledge developed in three rather separated communities of researchers: forest, fruit trees, and grapevines.

  • Functional Marine Biomaterials

    Properties and Applications
    • 1 Edición
    • Se-Kwon Kim
    • Inglés
    Functional Marine Biomaterials: Properties and Applications provides readers with the latest information on the diverse marine environment as a resource for many new substances, including biopolymers, bioceramics, and biominerals. As recent advances and funding has enabled scientists to begin harnessing many of these materials for biomedical applications from drug delivery to bone tissue engineering and biosensors, this important new text provides readers with a comprehensive review of these materials and their functional applications in the biomedical field. Chapters discuss the properties of the main classes of functional marine biomaterials, applications of marine products in tissue engineering, applications in drug delivery systems, and the role of marine derived materials in medical devices.

  • Biochemistry for Medical Professionals

    • 1 Edición
    • Tsugikazu Komoda + 1 más
    • Inglés
    Biochemistry for Medical Professionals contains pivotal advances in the biochemistry field and provides a resource for professionals across medicine, dentistry, pharmaceutical sciences and health professions who need a concise, topical biochemistry reference. Relevant, well-illustrated coverage begins with the composition of the human body and then goes into the technical detail of the metabolism of the human body and biochemistry of internal organs before featuring a biotechnology study inclusive of numerous methods and applications. The work is written at a consistently high level, with technical notes added to aid comprehension for complex topics.

  • Hair Analysis in Clinical and Forensic Toxicology

    • 1 Edición
    • Pascal Kintz + 2 más
    • Inglés
    Hair Analysis in Clinical and Forensic Toxicology is an essential reference for toxicologists working with, and researching, hair analysis. The text presents a review of the most up-to-date analytical methods in toxicological hair analysis, along with state-of-the-art developments in the areas of hair physiology, sampling, and pre-treatments, as well as discussions of fundamental issues, applications, and results interpretation. Topics addressed include the diagnosis of chronic excessive alcohol drinking by means of ethyl glucuronide (EtG) and fatty acid ethyl esters (FAEE), the early detection of new psychoactive substances, including designer drugs, the development of novel approaches to screening tests based on mass spectrometry, and the detection of prenatal exposure to psychoactive substances from the analysis of newborn hair.

  • The Ore Minerals Under the Microscope

    An Optical Guide
    • 2 Edición
    • Volumen 3
    • Bernhard Pracejus
    • Inglés
    The Ore Minerals Under the Microscope: An Optical Guide, Second Edition, is a very detailed color atlas for ore/opaque minerals (ore microscopy), with a main emphasis on name and synonyms, short descriptions, mineral groups, chemical compositions, information on major formation environments, optical data, reflection color/shade comparison with four common/standard minerals of a similar color or grey shade, and up to five high-quality photos for each mineral with scale. In addition, the atlas contains a compilation from some of the prominent publications in the field of ore microscopy presented on a list of 431 minerals.

  • Medicinal Plants

    Chemistry, Biology and Omics
    • 1 Edición
    • Da-Cheng Hao + 2 más
    • Inglés
    Medicinal Plants: Chemistry, Biology and Omics reviews the phytochemistry, chemotaxonomy, molecular biology, and phylogeny of selected medicinal plant tribes and genera, and their relevance to drug efficacy. Medicinal plants provide a myriad of pharmaceutically active components, which have been commonly used in traditional Chinese medicine and worldwide for thousands of years. Increasing interest in plant-based medicinal resources has led to additional discoveries of many novel compounds, in various angiosperm and gymnosperm species, and investigations on their chemotaxonomy, molecular phylogeny and pharmacology. Chapters in this book explore the interrelationship within traditional Chinese medicinal plant groups and between Chinese species and species outside of China. Chapters also discuss the incongruence between chemotaxonomy and molecular phylogeny, concluding with chapters on systems biology and “-omics” technologies (genomics, transcriptomics, proteomics, and metabolomics), and how they will play an increasingly important role in future pharmaceutical research.

  • Specialty Oils and Fats in Food and Nutrition

    Properties, Processing and Applications
    • 1 Edición
    • Geoff Talbot
    • Inglés
    Specialty Oils and Fats in Food and Nutrition: Properties, Processing and Applications examines the main specialty oils and fats currently in use in food processing, as well as those with significant potential. Specialty oils and fats have an increasing number of applications in the food industry, due to growing consumer interest in “clean label” functional foods and the emerging markets in “free-from” and specialist foods. Part One of this book covers the properties and processing of specialty oils and fats, with a focus on the chemistry, extraction, and quality of different fats and oils, including chapters on shea butter, tropical exotic oils, and structured triglycerides. Part Two looks at the applications of specialty oils and fats in different food and nutraceutical products, such as confectionary, ice cream, and margarine. Specialty Oils and Fats in Food and Nutrition is a key text for R&D managers and product development personnel working in the dairy, baking, and dairy analogue sectors, or any sector using fats and oils. It is a particularly useful reference point for companies reformulating their products or developing new products to alter fat content, as well as academics with a research interest in the area, such as lipid scientists or food scientists.

  • RGS Protein Physiology and Pathophysiology

    • 1 Edición
    • Volumen 133
    • Inglés
    RGS Protein Physiology and Pathophysiology describes the current, state-of-the-art research occurring in the laboratories of leaders in the RGS protein field that utilize genetic mouse models to interrogate the function of RGS proteins in vivo. Each chapter describes the elucidated role of a specific RGS protein or family of RGS proteins in normal physiology and/or disease with particular emphasis on how these discoveries inform healthcare and drug discovery. The work is a timely reference as drugs targeting G protein coupled receptors represent 40% of currently marketed therapeutics.

  • Healthy Babies Are Worth The Wait

    A Partnership to Reduce Preterm Births in Kentucky through Community-based Interventions 2007 - 2009
    • 1 Edición
    • Edward R.B. McCabe
    • Inglés
    Healthy Babies Are Worth the Wait®: A Collaborative Partnership to Reduce Preterm Births in Kentucky through Community-based Interventions 2007 – 2009 provides readers with an overview of the problem of preterm birth in the US, also describing in detail the design, implementation, evaluation, and outcomes of the Healthy Babies Are Worth the Wait initiative conducted in Kentucky between 2007 and 2009. The reader will learn about a unique research approach employing a mixed ecologic design that compared outcomes between intervention sites and comparison sites and the use of qualitative surveys and quantitative methods using state vital records data to evaluate outcomes. Consumer messaging and educational materials are discussed, along with the challenges of implementation and key lessons learned.

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