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Elsevier

Libros en Ciencias de la Vida

  • Mammalian Cell Membranes

    Volume 3, Surface Membranes of Specific Cell Types
    • 1 Edición
    • G. A. Jamieson + 1 más
    • Inglés
    Mammalian Cell Membranes, Volume Three: Surface Membranes of Specific Cell Types reviews the knowledge on surface membranes of the various cell types which have been studied in detail. This volume contains 10 contributions that cover the review of mammalian cell membranes. The topics discussed in the book include epithelial membranes and vitamin A, the erythrocyte, the platelet, and lymphoid cells. The carbohydrate components of tumor cell periphery, the composition and structure of excitable nerve membrane, and the role of membranes in the fertilization process are covered as well. Cytologists, molecular biologists, biochemists, and anatomists will find the book very invaluable.

  • Fundamentals of Enzyme Kinetics

    • 1 Edición
    • Athel Cornish-Bowden
    • Inglés
    Fundamentals of Enzyme Kinetics details the rate of reactions catalyzed by different enzymes and the effects of varying the conditions on them. The book includes the basic principles of chemical kinetics, especially the order of a reaction and its rate constraints. The text also gives an introduction to enzyme kinetics - the idea of an enzyme-substrate complex; the Michaelis-Menten equation; the steady state treatment; and the validity of its assumption. Practical considerations, the derivation of steady-state rate equations, inhibitors and activators, and two-substrate reactions are also explained. Problems after the end of each chapter have also been added, as well as their solutions at the end of the book, to test the readers' learning. The text is highly recommended for undergraduate students in biochemistry who wish to study about enzymes or focus completely on enzymology, as most of the mathematics used in this book, which have been explained in detail to remove most barriers of understanding, is elementary.

  • Leanness in Domestic Birds

    Genetic, Metabolic and Hormonal Aspects
    • 1 Edición
    • B. Leclercq + 1 más
    • Inglés
    Leanness in Domestic Birds: Genetic, Metabolic, and Hormonal Aspects is a proceeding of a symposium held in Tours, France, from 4 to 6 August 1987. Said symposium was concerned with genetic and metabolic factors associated with leanness of poultry and accounts of research in these areas. The book is divided into six parts. Part I covers studies that involve genetics in the selection of meat leanness. Part II deals with the relationship of feed intake and metabolism to the leanness of poultry. Part III discusses the lipid metabolism in birds and its related factors and effects. Part IV talks about the use of hormones such as insulin, thyroid hormones, and corticosteroids in the control of fatness in birds. Part V covers studies involving amino acid metabolism and its relation to leanness in poultry, and Part VI talks about the applications of the studies in commercial use. The text is recommended for zoologists, agriculturists, and poultry farmers who would like to know more about the different factors that affect the leanness of domestic birds and its implications.

  • Protides of the Biological Fluids

    Proceedings of the Twenty-Eighth Colloquium, 1980
    • 1 Edición
    • H. Peeters
    • Inglés
    Protides of the Biological Fluids covers the proceedings of the 28th Meeting on Protides of the Biological Fluids held in 1980. This book mainly focuses on the evolution of proteins; the molecular biology of blood coagulation and fibrinolysis; and the hybridomas. In studying the evolution of proteins, this text looks into the evolutionary studies of immunoglobulin protein and nucleic acid sequences, fibrinogen, proteases, and other proteins. This book then explains molecular biology of blood coagulation and fibrinolysis by explaining the Hageman factor, kallikrein–kinin system, human high molecular weight, and other biological processes involved. The hybridomas and monoclonal antibodies are also tackled by specifically discussing the production of monoclonal antibodies; monoclonal antibody conformation; and monoclonal antibodies against molecules. This publication will be invaluable to students, practitioners, and researchers in the field of biology and physiology who are interested in studying protides.

  • Europe—Japan

    Futures in Science, Technology and Democracy
    • 1 Edición
    • Vincent J. McBrierty
    • Inglés
    Europe-Japan: Futures in Science, Technology and Democracy presents the combined European and Japanese thinking on the implications of scientific and technological developments for society and democracy. This book addresses the challenges and the advantages that science and technology brings to Europe and Japan and explores how the process and application of scientific discovery can be beneficial to all people in the world. This monograph is comprised of six chapters and begins with a discussion on the impact of science on civilization and democracy, with emphasis on the challenges and opportunities afforded by technological innovations. The implications of advances in biology and medicine for human rights are the subject of the next chapter, paying particular attention to the themes of freedom, ethics, and the role of communication and dialogue in society. This book also explores cooperation and competition in science and advanced technology before concluding with a chapter that describes the scientific and technological linkages between Europe and Japan. This text will be a valuable resource for policymakers, parliamentarians, scientists, and others who are concerned with the increasingly complex arena of science and politics.

  • A History of Medical Bacteriology and Immunology

    • 1 Edición
    • W. D. Foster
    • Inglés
    A History of Medical Bacteriology and Immunology provides the account of the history of bacteriology from the year 1900 to 1938. This book presents details about the discovery of the important pathogenic bacteria of man, of how they were shown to be causally related to disease, and of the use of these discoveries in the diagnosis, treatment, and prevention of disease. Other topics discussed include the development of the germ theory of infectious diseases; contribution of Louis Pasteur and Robert Koch to medical bacteriology; and discovery of the more important human pathogenic bacteria. This text also discusses the scientific basis and practical application of immunology to medicine; main developments in bacteriology during the early 20th century; and chemotherapy of bacterial disease. This medically oriented text is beneficial for students and individuals conducting study on medical bacteriology and immunology.

  • Supramolecular Enzyme Organization

    Quaternary Structure and Beyond
    • 1 Edición
    • Peter Friedrich
    • Inglés
    Supramolecular Enzyme Organization: Quaternary Structure and Beyond provides a comprehensive discussion of enzyme interactions. It attempts to place conceptually related phenomena in a common perspective by first scrutinizing enzyme interactions at the quaternary level and then moving on towards higher orders of organization. The book begins with a discussion of the hierarchy of enzymes, covering the structure of monomeric enzymes, enzyme structures beyond the monomeric stage, and protein-protein interactions. Separate chapters cover the chemistry of protein associations; the quaternary structure of enzymes; multienzyme systems; multienzyme complexes and conjugates; the association of enzymes with cellular structures; and metabolite compartmentation. The final chapters discuss trends in the study of enzyme systems and the dialectics of enzymology. This book is intended, not for the specialist, who knows much more about the individual questions than the text offers, but rather for the general biochemical reader interested in enzyme organization. There is practically no mathematics involved. Instead, quite elementary things are described, so that students and biologists with less background knowledge on enzymes will be able to join in.

  • Subcellular Components

    Preparation and Fractionation
    • 2 Edición
    • G. D. Birnie
    • Inglés
    Subcellular Components: Preparation and Fractionation talks about cells and particles' components, including their preparation and fractionation. The book includes theories and answers to questions that are relevant to the study. The first chapter of the book details various facts about homogenization of mammalian cells. This chapter presents the results of studies on solid tissues and single-cell suspensions; the author then offers his conclusion of the study. The next two chapters highlight the methods on isolating nuclei, including the guides for standard assessment and the procedure of isolation, along with analysis of nuclei biochemical properties. The main topics in Chapter 4 are mitochondria from animal tissues and yeasts; this chapter also discusses the preparation for a rat-liver, blowfly flight-muscle, yeast, and brain mitochondria. The chapter that follows widely talks about lysosomes, including its historical background, centrifugal method, and related topics. In the next several chapters, the topics covered include purification, isolation, preparation, and separation of cells including plasma-membrane, polysomes, ribosomes, microsomes, and microvilli. The book serves as a great reference for undergraduates and postgraduates in the field, as it contains a thorough discussion of various relevant studies.

  • Mammalian Cell Membranes

    General Concepts
    • 1 Edición
    • G. A. Jamieson + 1 más
    • Inglés
    Mammalian Cell Membranes, Volume 1: General Concepts is a collection of papers that deals on the physical and chemical studies focusing on membrane structure and function. This collection reviews the interpretation of the anatomy of the mammalian cell, including its separation and cultivation. The different methods of isolation of its surface membrane are then evaluated to bring some understanding of the subject. More descriptions of the various physical techniques adopted to membrane constituents and to cell membrane research, such as nuclear magnetic resonance, electron spin resonance, fluorescence, and flash photolysis spectroscopy are given. Discoveries of mitochondrial DNA and other techniques have increased investigation of the synthesis and components of functional mitochondria, leading to different perspectives on models of membrane structure. This book can serve the needs of biochemists and microbiologists in advancing their work, research, and understanding of mammalian cell membranes.

  • Membrane Glycoproteins

    A Review of Structure and Function
    • 1 Edición
    • R. Colin Hughes
    • Inglés
    Membrane Glycoproteins: A Review of Structure and Function deals with membrane glycoproteins found in biological systems. The book describes the structure and biosynthesis of the glycoproteins in relation to known or postulated functions in membranes. The text opens with an introduction and a topic on detection and distribution of membrane glycoproteins. The book then notes that the isolation of membrane glycoproteins brought by the progress in research and technology of membrane solubilization and purification of the soluble components is now possible. Discussion is also directed to glycoproteins as being integral components of intracellular membranes, and not just located on cell surfaces. Through the structural analysis of glycoproteins produced by the secretory glands, analysis of human blood group antigens is available. Likewise, discoveries are made, explaining that lectins are useful reagents in detecting the type and numbers of glycoproteins found on cellular members. Lectins are likewise being widely used in tests for carbohydrate-contain... substances in membrane-mediated processes. The metabolism, growth control, and cell surface reactions of membrane glycoproteins are also explained. The book can serve as a guide for biologists, chemists, biochemists, and academicians interested in the study of membranes or glycoproteins.

  • Nuclear Pore Complexes and Nucleocytoplasmic Transport - Methods

    • 1 Edición
    • Volumen 122
    • Inglés
    Volume 122 of Methods in Cell Biology describes modern tools and techniques used to study nuclear pore complexes and nucleocytoplasmic transport in diverse eukaryotic model systems (including mammalian cells, Xenopus, C. elegans, yeast). The volume enables investigators to analyze nuclear pore complex structure, assembly, and dynamics; to evaluate protein and RNA trafficking through the nuclear envelope; and to design in vivo or in vitro assays appropriate to their research needs. Beyond the study of nuclear pores and transport as such, these protocols will also be helpful to scientists characterizing gene regulation, signal transduction, cell cycle, viral infections, or aging. The NPC being one of the largest multiprotein complexes in the cell, some protocols will also be of interest for people currently characterizing other macromolecular assemblies. This book is thus designed for laboratory use by graduate students, technicians, and researchers in many molecular and cellular disciplines.

  • Advances in Clinical Chemistry

    • 1 Edición
    • Volumen 65
    • Inglés
    Volume 65 in the internationally acclaimed Advances in Clinical Chemistry contains chapters authored by world renowned clinical laboratory scientists, physicians and research scientists. The serial provides the latest and most up-to-date technologies related to the field of Clinical Chemistry and is the benchmark for novel analytical approaches in the clinical laboratory.

  • Immunology

    • 1 Edición
    • Lars Å. Hanson + 1 más
    • Inglés
    Immunology focuses on the study of immunology. The first half of this book provides a treatise of basic immunology, while the rest is more clinically orientated and illustrates the importance of immune mechanisms for health and disease. This text emphasizes the three good reasons why immunology should be studied. First is that man cannot survive without immunological defense against foreign material. Second is that these same immunological defense mechanisms can cause various forms of tissue damage that result in different diseases. Finally, some immunological reactions can be used as sensitive and highly specific methods for analytical and diagnostically useful determinations of low molecular substances. This publication is primarily intended for students of medicine and natural sciences, as well as clinicians concerned with the field of immunology.

  • Footprinting of Nucleic Acid-Protein Complexes

    • 1 Edición
    • Inglés
    Footprinting of Nucleic Acid-Protein Complexes provides protocols for studying the stoichiometry, binding site size and location, and structural changes in nucleic acids caused by their interaction with proteins. The methods are central to studying key biological processes, such as transcription and translation. The techniques are important to experiments in vivoand in vitro, in eukaryotes and in prokaryotes, at qualitative and quantitative levels,and across many disciplines.This book is a laboratory manual of footprinting techniques for studying nucleic acid-protein interactions. It contains clear and concise descriptions of the most important methodologies, and includes in vivo as well as in vitro applications. It is aimed at bench scientists from graduate students on, and should be of value in industrial labs as well as in academic settings. Use of different footprinting approaches can provide unique insights into DNA-protein systems. The protocols containedin this handbook are written to be"user-friendly,"an... thus should be conducive to extending the use of footprinting to new systems. The section on quantitative analysis of DNAse I footprints should prove especially useful for in depth evaluation of cooperative interactions.

  • Learning and Memory

    A Biological View
    • 2 Edición
    • Joe L. Martinez Jr. + 1 más
    • Inglés
    This book presents a comprehensive, up-to-date overview of brain*b1behavior relations as they bear on learning and memory. The structure of memory is investigated from a diversity of approaches, including anatomical, pharmacological, electrophysiological and lesions, and through the use of different populations, such as invertebrate, vertebrate, and human.

  • Cellular Immunology LabFax

    • 1 Edición
    • Inglés
    LABFAX volumes are purpose-designed data reference books for practicing scientists. Each book presents the key information for a major subject in one place and so saves hours of searching. The authors and editors of each LABFAX volume have searched the original literature for the accurate data they know the subject specialist needs.Cellular Immunology Labfax is a detailed compendium of information on the tissues and cells of the immune system, cell lines and hybridomas, antigens and receptors, the major histocompatibility complex, soluble immunoregulatory molecules, in vivo procedures, important features of species used in immunological research, and much more.The contents of Cellular Immunology Labfax have been carefully chosen to complement the data presented in Immunochemistry Labfax. It is therefore the companion volume to this text.

  • Virgin Lands

    Two Years in Kazakhstan, 1954-5
    • 1 Edición
    • L. I. Brezhnev
    • Inglés
    Virgin Lands: Two Years in Kazakhstan, 1954-5 focuses on the life, career, and experiences of L. I. Brezhnev when he stayed in Kazakhstan to push for the improvement of the agriculture sector of the country. The book first offers information on the experiences of L. I. Brezhnev as a farmer, land-use surveyor, metallurgist, factory worker, and politician. Brezhnev underscores how he pushed for the organization of collective farms. The text also highlights the poor state of agriculture in the country, including the farming methodologies that Brezhnev and his countrymen have adopted to overcome the extreme conditions of farming lands. The manuscript details the improvement of state farms, particularly noting the increase in harvest and the number of farms to be set up. Brezhnev narrates how the state farms are affected by drought and extreme weather conditions, and how they have doubled the crop areas through the use of farm implements. The book also underscores the role of farm machineries in the increase of production of grain, meat, and vegetables. The text is a dependable source of data for readers interested in the life and career of L. I. Brezhnev, particularly his dedication to develop agriculture in Kazakhstan.

  • Recombinant DNA Methodology

    • 1 Edición
    • Inglés
    Recombinant DNA methods are powerful, revolutionary techniques that allow the isolation of single genes in large amounts from a pool of thousands or millions of genes and the modification of these isolated genes or their regulatory regions for reintroduction into cells for expression at the RNA or protein levels. These attributes lead to the solution of complex biological problems and the production of new and better products in the areas of medicine, agriculture, and industry.Recombinant DNA Methodology, a volume in the Selected Methods in Enzymology series produced in benchtop format, contains a selection of key articles from Volumes 68, 100, 101, 153, 154, and 155 of Methods in Enzymology. The essential and widely used procedures provided at an affordable price will be an invaluable aid to the graduate student and the researcher.

  • A New Approach to Teaching and Learning Anatomy

    Objectives and Learning Activities
    • 1 Edición
    • Michael J. Blunt
    • Inglés
    A New Approach to Teaching and Learning Anatomy: Objectives and Learning Activities presents sets of general instructional and specific behavioral objectives to define the framework of a course in human anatomy. The objectives are preceded by explanatory notes which deal with the principles and the techniques involved in their formulation so that their expansion or modification may be facilitated. Methods of using the objectives as guides to study are also suggested. This book is comprised of 13 chapters and begins with an introduction to the goals to be adopted for the course framework and the general objectives that will indicate course content as well as the sequence of learning. The discussion then turns to specific behavioral objectives and student-centered learning activities, followed by an outline of the anatomy course. The course is broken down into regions and systems and covers the anatomy of bones, joints, and muscles, along with peripheral nerves and vessels. The anatomy of the upper limb, head and neck, walls of thorax and abdomen, and the lower limb are considered. The viscera are ""fitted in"" to the musculo-skeletal framework on a systematic basis, and the course outline concludes with a section on neurological anatomy, that is, the cardiovascular system, respiratory system, gastrointestinal system, genito-urinary system, and neuroendocrine system. This monograph should be useful to those who are engaged in teaching-learning programs in anatomy whether as medical educators or as students.

  • Enzyme Regulation and Mechanism of Action

    Proceedings of the FEBS Special Meeting on Enzymes, Cavtat, Dubrovnik, 1979
    • 1 Edición
    • P. Mildner + 1 más
    • Inglés
    Enzyme Regulation and Mechanism of Action contains the proceedings of the Federation of European Biochemical Societies' Special Meeting on Enzymes held in Dubrovnik, Croatia in 1979. The meeting provided a forum for reviewing advances in understanding the regulation and mechanism of action of enzymes. The discussions are organized around three themes: regulation of enzyme activity; the role of enzymes in the synthesis of nucleic acids and proteins; and proteolytic enzymes. Comprised of 33 chapters, this volume begins with an analysis of partial amino acid sequence of rabbit liver fructose 1,6-bisphophatase and sites of cleavage by proteinases. The reader is then introduced to physiological inactivation of enzymes in yeasts; structure and functions of protein kinases; and control points in the citric acid cycle. Subsequent chapters focus on ligand binding properties and subunit interactions in yeast alcohol dehydrogenase; the role of water in the acceleration of an enzymatic reaction; DNA polymerases of human normal and leukemic cells; and the phylogenetic and developmental aspects of gastric proteinases and their zymogens. This book is intended for enzymologists.

  • Introduction to Biostatistics

    A Guide to Design, Analysis and Discovery.
    • 1 Edición
    • Ronald N. Forthofer + 1 más
    • Inglés
    The Biostatistics course is often found in the schools of public Health, medical schools, and, occasionally, in statistics and biology departments. The population of students in these courses is a diverse one, with varying preparedness. The book assumes the reader has at least two years of high school algebra, but no previous exposure to statistics is required.Written for individuals who might be fearful of mathematics, this book minimizes the technical difficulties and emphasizes the importance of statistics in scientific investigation. An understanding of underlying design and analysis is stressed. The limitations of the research, design and analytical techniques are discussed, allowing the reader to accurately interpret results. Real data, both processed and raw, are used extensively in examples and exercises. Statistical computing packages - MINITAB, SAS and Stata - are integrated. The use of the computer and software allows a sharper focus on the concepts, letting the computer do the necessary number-crunching.

  • Single Neuron Computation

    • 1 Edición
    • Thomas M. McKenna + 2 más
    • Inglés
    This book contains twenty-two original contributions that provide a comprehensive overview of computational approaches to understanding a single neuron structure. The focus on cellular-level processes is twofold. From a computational neuroscience perspective, a thorough understanding of the information processing performed by single neurons leads to an understanding of circuit- and systems-level activity. From the standpoint of artificial neural networks (ANNs), a single real neuron is as complex an operational unit as an entire ANN, and formalizing the complex computations performed by real neurons is essential to the design of enhanced processor elements for use in the next generation of ANNs.The book covers computation in dendrites and spines, computational aspects of ion channels, synapses, patterned discharge and multistate neurons, and stochastic models of neuron dynamics. It is the most up-to-date presentation of biophysical and computational methods.

  • Biochemical Disorders of the Skeleton

    Postgraduate Orthopaedics Series
    • 1 Edición
    • Roger K. W. Smith
    • Inglés
    Biochemical Disorders of the Skeleton explores the biochemical and clinical aspects of skeletal disorders, including osteoporosis, osteomalacia, Paget's disease of bone, osteogenesis imperfecta, and Marfan's syndrome. Homocystinuria, Ehlers-Danlos syndrome, mucopolysaccharidose... hyperphosphatasia and hypophosphatasia, and fibrous dysplasia are also considered. Comprised of 12 chapters, this book begins with an overview of the physiology of bone, with emphasis on the structures produced by bone cells and the different hormones that influence them. The symptoms, signs, and investigation of metabolic bone disease are then described and compared. The following chapters focus on the biochemistry and clinical aspects of disorders affecting the skeleton, from osteoporosis and osteomalacia to Ehlers-Danlos syndrome, fibrous dysplasia, osteopetroses and hyperostoses, and fibrogenesis imperfecta ossium. The final chapter offers a short description of advances that have been made in understanding these biochemical disorders, including the significance of low-plasma calcitonin in women; the role of mithramycin in Paget's disease; and the identification of the different types of osteogenesis imperfecta. This monograph will be a valuable resource for physicians, pediatricians, and orthopedic surgeons.

  • Organization and Practice in Tuberculosis Bacteriology

    • 1 Edición
    • C. H. Collins + 2 más
    • Inglés
    Organization and Practice in Tuberculosis Bacteriology focuses on the organization and technical methods of tuberculosis bacteriology. This book discusses the mycobacteria and mycobacterial disease and role and scope of the tuberculosis laboratory in human and veterinary medicine and epidemiology. The organization of tuberculosis laboratory services; collection, preservation and transport of specimens; and examination of direct smears are also elaborated. This text likewise covers the decontamination of specimens, inoculation of culture media, and identification of species and variants of tubercle bacilli. Other topics include the drug sensitivity tests, animal inoculation and assay tests; problems faced in the therapy of tuberculosis, and lipid chromatography. This publication is suitable for biologists, medical practitioners, and clinicians concerned with tuberculosis bacteriology.

  • Bone Tumours in Man and Animals

    • 1 Edición
    • L. N. Owen
    • Inglés
    Bone Tumours in Man and Animals covers advances in the understanding of the pathogenesis of bone neoplasia in humans and animals as well as their diagnosis and treatment. In the case of animals, particular emphasis is placed on dogs. This book is comprised of 15 chapters and begins by introducing the reader to the principles of diagnosis, including biopsy and bone scanning, and methods of treatment employed for bone tumors in human and animal patients, including surgery, radiotherapy, and chemotherapy. The following chapters focus on bone cysts and benign tumors of osseous origin; osteosarcoma in humans and animals such as dogs, cats, and mice; and tumors of cartilaginous origin such as solitary enchondroma, enchondromatosis, chondroblastoma, and chondromyxoid fibroma. Tumors arising from fibrous, fatty, neurological, or undifferentiated connective tissue are also considered, along with those arising from bone marrow or lymphoid tissue. This book concludes by offering suggestions for future research. This text is intended for clinicians, radiologists, and pathologists, both medical and veterinary, as well as for biologists, biochemists, and radiation physicists.

  • Immunogenetics

    • 1 Edición
    • Gabriel S Panayi + 1 más
    • Inglés
    Immunogenetics is a 12-chapter book that begins with the elucidation of the major histocompatibility complex genes and their role in autoimmune and infectious diseases. Subsequent chapters explore the human major histocompatibility complex, including implications of their complement genes for linkage disequilibrium and disease associations. This book also describes the genetics of human immunoglobulins; T-cell clones; genes of the major histocompatibility complex of the mouse; and the generation, characterization, and use of monoclonal antibodies of murine and human origin. Specific diseases are also discussed; these include spondoarthritides, rheumatoid arthritis, systemic lupus erythematosus, multiple sclerosis, and autoimmune thyroid disease. This book will be of beneficial value to specialists in infectious diseases, endocrinology, connective tissue diseases, and neurology, as well as to medical scientists in immunology and molecular biology.

  • Virology

    A Laboratory Manual
    • 1 Edición
    • Florence G. Burleson + 2 más
    • Inglés
    Virology: A Laboratory Manual is designed for a one-semester virology laboratory course, although more than one semester of exercises are included. Choices of experiments allow for flexibility within a sequentially organized framework. The text features detailed experimental protocols with comprehensive sections on materials and preparations for all exercises, plus introductory material, discussion questions, and further reading. the use of few viruses and cell lines provides continuity and simplifies preparation of the laboratory exercises. An Instructor's Manual is available to give alternative and assistance in laboratory set-up.

  • High Technology Aids for the Disabled

    • 1 Edición
    • W.J. Perkins
    • Inglés
    High Technology Aids for the Disabled presents some technical aids and microcomputers for the disabled. This technology could herald a major advance in improving the quality of life of many disabled people. Organized into four parts, this book begins with an assessment of disability. This book then presents a very wide variety of bioengineering approaches to replacement of function. Subsequent chapters explore the reduction of handicap using computer technology, following three main themes: microcomputer systems, user input controls, and speech training and recognition. The last part discusses the collaboration with user organizations in the development of technological aids. This book will be useful for disabled people in coping with their respective difficulties and for those people involved in helping disabled people maximize their human potential.

  • Cellular Pathology Technique

    • 4 Edición
    • C. F. A. Culling + 2 más
    • Inglés
    Cellular Pathology Technique aims to maintain the twin objectives of producing a comprehensive bench book and a text for students that will take the Special Examination in Cellular Pathology of the Institute of Medical Laboratory Sciences. The organization of this fourth edition has been reshaped. Some sections were expanded such as those about the theory of staining, and new chapters were added dealing with immunolocalization, the endocrine system, and quantification. This book is organized into 10 parts. The introductory part provides basic information on cells and tissues and outlines the methodology in cellular pathology techniques. This is followed by chapters that deal with various aspects of cellular pathology including tissues, cells and cell products of special interests, electron microscopy, and immunocytochemistry. This book will be of interest to students of cellular pathology and those in the medical profession.

  • Lipid Metabolism in Ruminant Animals

    • 1 Edición
    • William W. Christie
    • Inglés
    Lipid Metabolism in Ruminant Animals is a nine-chapter book that first discusses the anatomy, physiology, and microbiology of the ruminant digestive tract. Subsequent chapters center on lipid metabolism in the rumen; digestion, absorption and transport of lipids in ruminant animals; the composition, structure and function of lipids in the tissues of ruminant animals; and the effects of diet and other factors on the lipid composition of ruminant tissues and milk. Other chapters focus on lipid metabolism in the mammary gland, adipose tissue, liver, and other selected tissues of ruminant animals.

  • Antimetabolites in Biochemistry, Biology and Medicine

    Proceedings of a Symposium on Antimetabolites in Biochemistry, Biology and Medicine, Held in Prague, Czechoslovakia, July 10-12, 1978
    • 1 Edición
    • J. Skoda + 1 más
    • Inglés
    FEBS: Federation of European Biochemical Societies, Volume 57: Antimetabolites in Biochemistry, Biology, and Medicine is a collection of papers that presents that advancement in the field of antimetabolites research. The title first covers the use of antimetabolites in enzymology, and then proceeds to tackling the consequences of analog incorporation into nucleic acids. Next, the selection discusses the rational approach to the use of antimetabolite in commination cancer chemotherapy an in immunosuppression. The text also covers the aspects of selective antiviral action. In the last part, the selection details various compounds, along with their synthesis and mechanisms of action. The book will be of great use to researchers and practitioners of biochemistry, biology, and medicine.

  • Lipids: Structure and Function

    The Biochemistry of Plants
    • 1 Edición
    • Volumen 9
    • P. Michael Conn
    • Inglés
    The Biochemistry of Plants: A Comprehensive Treatise, Volume 9: Lipids: Structure and Function focuses on the advancements in the methodologies, principles, techniques, and technologies involved in plant lipid research. The selection first elaborates on the analysis and structure determination of acyl lipids, oxidative systems for modification of fatty acids, and lipases. Topics include lipid acyl hydrolases, properties of the lipoxygenase reaction, metabolism of the hydroperoxide products of lipoxygenase, physical and chemical methods of structure determination, and chromatographic methods of separation. The manuscript then examines the biosynthesis of saturated fatty acids, biochemistry of plant acyl carrier proteins, and biosynthesis of monoenoic and polyenoic fatty acids. Discussions focus on polyunsaturated fatty acid biosynthesis and regulation, molecular biology, and immunological characterization of acyl carrier proteins. The publication ponders on lipids of blue-green algae, lipid-derived defensive polymers and waxes and their role in plant-microbe interaction, sulfolipids, and galactolipid synthesis. The selection is a vital source of information for researchers interested in the structure and functions of lipids.

  • Nasals, Nasalization, and the Velum

    • 1 Edición
    • Volumen 5
    • Inglés
    Although nasalization has been discussed in the context of more general aspects of linguistics in other books, this text is the first and primary resource focusing solely on nasalization. This volume features articles discussing all aspects of nasalization, including physiology, perception, aerodynamics, acoustics, phonetic and phonological representations, research methodology, and instrumentation. Each chapter examines important research advances achieved within the last ten years and closes with a detailed discussion of the current research.

  • Current Issues in the Education of Students with Visual Impairments

    • 1 Edición
    • Volumen 46
    • Inglés
    International Review of Research in Developmental Disabilities is an ongoing scholarly look at research into the causes, effects, classification systems, and syndromes of developmental disabilities. Contributors come from wide-ranging perspectives, including genetics, psychology, education, and other health and behavioral sciences. The current volume, number 46, addresses current issues in the education of students with visual impairments. Topics covered include the expanded core curriculum for students with visual impairment; assistive technology; Braille reading comprehension; communication development; orientation and mobility issues, and more.

  • Fungi

    • 1 Edición
    • Volumen 70
    • Inglés
    Advances in Botanical Research publishes in-depth and up-to-date reviews on a wide range of topics in plant sciences. Currently in its 70th volume, the series features several reviews by recognized experts on all aspects of plant genetics, biochemistry, cell biology, molecular biology, physiology and ecology. This thematic volume features reviews on fungi, including pathogenic fungi, symbiotic fungi, saprotrophic fungi and population genomics.

  • Atlas of Chick Development

    • 3 Edición
    • Ruth Bellairs + 1 más
    • Inglés
    The Atlas of Chick Development, Third Edition, a classic work covering all major event of chick development, is extensively updated with new and more detailed photographs, enlargements showing regions of special-interest and complexity, and new illustrations. The revised text and expanded illustrative material describe the intricate changes that take place during development, together with accounts of recent experimental and molecular research that has transformed our understanding of morphogenesis. These wide-ranging updates make this book an essential resource for developmental biologists, geneticists, molecular biologists, poultry scientists, biochemists, immunologists, and other life scientists who use the chick embryo as their research model. Individuals joining this burgeoning area, ignited by the increased insight into events surrounding organ and tissue differentiation, will find this a valuable tool to help grow a basic knowledge of morphogenesis.

  • Albumin: Structure, Function and Uses

    • 1 Edición
    • Victor M. Rosenoer + 2 más
    • Inglés
    Albumin Structure, Function and Uses reviews the many facets of serum albumin, including its history and evolutionary development, structure and function, synthesis, degradation, distribution and transport, and metabolic behavior. The use, misuse, and abuse of albumin in the treatment of disease are also discussed. This book is comprised of 17 chapters and begins with a commentary on how albumin is used, misused, and abused in the treatment of disease such as peptic ulcer, and a description of the real indications for its use. Concepts in albumin purification are then examined, along with the amino acid sequence of serum albumin and some aspects of its structure and conformational properties. Subsequent chapters explore the phylogenetics of albumin; albumin binding sites; clinical implications of drug-albumin interaction; genetics of human serum albumin; and hepatic synthesis of export proteins. Albumin catabolism and intracellular transport are also considered, together with surgical and clinical aspects of albumin metabolism. This monograph should be a useful resource for biochemists and clinicians.

  • Catecholamines and Schizophrenia

    • 1 Edición
    • Steven W. Matthysse + 1 más
    • Inglés
    Catecholamines and Schizophrenia reviews research linking catecholamines to schizophrenia. Topics include the relationship between stereotyped behavior and amphetamine psychosis, between antipsychotic drugs and catecholamine synapses, and between biogenic amines and behavior. The chemical neuropathology of schizophrenia, enzymology and regulation of catecholamine enzymes, and advances in histochemical technologies used in neurochemical pathology are also covered. This book consists of 47 chapters organized into six sections. After giving an overview of the pharmacology and physiology of stereotyped behavior, this book discusses the behavioral and biochemical aspects of amphetamine psychosis; stereoselective features of catecholamine disposition and their behavioral implications; and the effects of amphetamines on catecholamine metabolism. A two-factor theory of schizophrenia is also presented. The chapters that follow focus on the role of monoamine oxidase in schizophrenia and other behavioral disorders; the chemical pathology of schizophrenia; genetic control of biogenic amines; and dopamine-beta-hydrox... This book will be of value to students, researchers, and practitioners in fields ranging from neuropharmacology and physiology to biology, biochemistry, psychiatry, and psychology.

  • Protides of the Biological Fluids

    Proceedings of the Twenty-Third Colloquium, Brugge, 1975
    • 1 Edición
    • H. Peeters
    • Inglés
    Protides of the Biological Fluids contains the proceedings of the 23rd Colloquium on "Protides of the Biological Fluids" held in Brugge, Belgium in 1975. The discussions were organized around three themes: proteinase inhibitors, clinical evaluation of plasma protein patterns, and affinity chromatography. Comprised of 117 chapters, this volume begins with an overview of carcinofetal proteins, followed by an analysis of proteinase inhibition. The reader is then introduced to the mechanism and structure of human alpha-1-proteinase inhibitor; some properties of a complex between ?2-macroglobulin and brinase; and the interaction of proteinase inhibitors with blastocyst proteinases involved in implantation. Subsequent chapters deal with the thermodynamics and kinetics of the interaction of trypsin with trypsin inhibitors; purification and characterization of acid-stable proteinase inhibitors from human seminal plasma; and the possible role of protease inhibitors in cartilage metabolism. The book also explores the structure and function of animal proteinase inhibitors as well as techniques and methods used in clinical evaluation of plasma protein patterns. This monograph will be of interest to biologists and research workers in biology.

  • Extraretinal Photoreception

    Proceedings of the Symposium and Extraretinal Photoreception in Circadian Rhythms and Related Phenomena
    • 1 Edición
    • Michael Menaker
    • Inglés

  • Gene Expression

    Protein Synthesis and Control RNA Synthesis and Control Chromatin Structure and Function
    • 1 Edición
    • Brian F. C. Clark + 2 más
    • Inglés
    Gene Expression provides research papers on selected topics in gene expression, presented at the 11th meeting of the Federation of European Biochemical Societies, held at Copenhagen in August 1977. The book presents research knowledge provided by eminent researchers in the field of biochemistry. Each chapter contains material that is important to other researchers, such as on initiation mechanism of protein synthesis in prokaryotes; translocation mechanism of the ribosome; and analysis of ribosomal translocation by drugs. Mechanisms for the intracellular compartmentation of newly synthesized proteins; RNA synthesis and control; the sub-structure of nucleosome core particles; and future prospects on chromosome structure and function are detailed as well. The text will be of use to researchers and workers in the field of medicine, pharmacology, gene therapy, and biochemistry.

  • The Evolution of the Bioenergetic Processes

    • 1 Edición
    • E. Broda
    • Inglés
    The Evolution of the Bioenergetic Processes deals with the evolution of the bioenergetic processes, from fermentation to photosynthesis and respiration, and their interrelationships in prokaryotes and eukaryotes. Topics covered range from the origin of life to the evolution of eobionts, organisms, and energy-rich compounds. Fermentation, photoorganotrophy, and photosynthesis in bacteria and plants are also discussed. Comprised of 25 chapters, this book begins with an overview of energy and entropy in the biosphere, followed by a detailed treatment of the evolution of bioenergetics based on the pattern of the bioenergetic processes in extant organisms. The reader is then introduced to the events involved in the origin of life; the evolution of eobionts and organisms; and the origin of energy-rich compounds, particularly nucleotides of the adenylic acid system. Subsequent chapters focus on fermentation and photosynthesis; assimilation of carbon dioxide; photoorganotrophy, chemolithotrophy, and photolithotrophy; and aerobic and anaerobic respiration of prokaryotes. The book also considers the energy supply of protozoa and fungi before concluding with an analysis of the history of atmospheric oxygen. This monograph will be of interest to evolutionary biologists.

  • Biochemical Aspects of New Protein Food

    FEBS Federation of European Biochemical Societies 11th Meeting Copenhagen 1977, Volume 44 Symposium A3
    • 1 Edición
    • Jens Adler-Nissen + 2 más
    • Inglés
    Biochemical Aspects of New Protein Food examines the biochemical aspects of the use and consumption of new protein foods and determine future areas for research by biochemists. The symposium showcases the presentation of biochemical research that provides a better understanding of the characteristics of new protein foods; their methods of production; and solutions to problems in the evaluation of their nutritive properties. Chapters are devoted to the novel and conventional protein foods in the future; production of food from waste; and a comparative analysis of protein situation in developed versus developing countries. It is hoped that the symposium will be able to help overcome the problems of acceptability of the new foods and catapult it as an important part of human diet. Biochemists, food technologists, biologists, and food manufacturers will find the book interesting and informative.

  • Frontiers in Catecholamine Research

    Proceedings of the Third International Catecholamine Symposium Held at the University of Strasbourg, Strasbourg, France May 20–25, 1973
    • 1 Edición
    • Earl Usdin + 1 más
    • Inglés
    Frontiers in Catecholamine Research is a collection of papers presented at the Third International Catecholamine Symposium, held at the University of Strasbourg, Strasbourg, France, on May 20-25, 1973. This book is organized into nine parts encompassing 205 chapters. The text begins with a discussion on clinically and experimentally used drugs that have been developed or whose mechanism of action has been clarified through monoamine research. Parts II and III deal with enzymes related to catecholamine studies, their properties, regulation, genetics, mechanism of action, and localization. Parts IV and V examine the concepts of synaptic dynamics of brain regulators and the isolation, characterization, methods of analysis, and mechanism of action of catecholamines. Part VI focuses on the complexities that surround the extrapolation of catecholamine function into the realms of electrophysiology and behavior. Part VII discusses the metabolism, behavioral, neurological, and physiological effects of amphetamine and other drugs of abuse. The concluding parts describe the role of catecholamine and its metabolism in neurologic diseases, such as schizophrenia.

  • Regulatory Proteolytic Enzymes and Their Inhibitors

    11th Meeting Copenhagen 1977
    • 1 Edición
    • Staffan Magnusson + 2 más
    • Inglés
    Regulatory Proteolytic Enzymes and Their Inhibitors consists of contributed papers from the 11th Meeting of the Federation of European Biochemical Societies in Copenhagen in 1977. This collection describes the role of proteases in the physiological regulation, a matter of the activation and de-activation of enzymes. The text also discusses the activation mechanism of pepsinogen and other acid protease zymogens. One paper reviews a discovery — that of a separate and distinct class of precursors, the pre-secretary proteins, and then discusses other studies on preproinsulin. The text then discusses the primary structures and presumed functions of immunoglobulin precursors. Another paper continues with the work of Reich and co-workers who found that transformation of cultured fibroblasts from different species by oncogenic viruses is related to the production and release of proteases that are responsible in activating the proenzyme plasminogen into plasmin. Another paper discusses plasminogen activation as having some relationship with pathological processes. The book also reviews the plasminogen activator secretion by normal and neoplastic human tissues. The text discusses the results when primary cultures established from biopsies of normal kidneys secreted plasminogen activators in amounts over those secreted by actual malignant tissues. The book then notes the role of neutral and acid proteinases in male reproduction and the role of plasminogen activators in female ovulation. This collection can be useful for micro-biologists, research biologists, molecular scientists, and students of molecular biology.

  • Recent Advances in Steroid Biochemistry

    • 1 Edición
    • J. R. Pasqualini
    • Inglés
    Recent Advances in Steroid Biochemistry contains the proceedings of the Second International Symposium of the Journal of Steroid Biochemistry. Separating 38 papers as chapters, this book discusses the partial purification of steroid-receptor complexes; enzymatic techniques in steroid assay; mass fragmentography of steroid hormones; biological consequences of 18-hydroxylation; and steroidogenesis in adrenal cells. This text also explores the regulation of steroidogenesis in testis; androgen binding proteins in different testis compartments; nuclear acceptor sites for glucocorticoid receptors; estrogen receptors in the pancreas; and molecular mechanisms of steroid hormone action.

  • Clinical Tumor Immunology

    • 1 Edición
    • Joseph Wybran + 1 más
    • Inglés
    Clinical Tumor Immunology contains the proceedings of the Symposium of Clinical Tumor Immunology held in Brussels, Belgium, on May 26-29, 1975) and organized by the European Organization for Research on Treatment of Cancer in cooperation with the Department of Immunology of the University Hospital of Brussels. The papers explore progress in the field of clinical tumor immunology and cover topics ranging from general mechanisms in tumor immunity to tumor antigens and immunotherapy. A classification of leukemias and lymphomas is also presented. Comprised of 48 chapters, this book begins with an overview of the biological activities of the circulating thymic hormone, followed by a discussion on macrophage secretions affecting the growth of other cells. The reader is then introduced to immune cellular mechanisms at the site of the tumor; the use of the leukocyte migration technique in studies of tumor-directed cellular immunity in malignant melanoma; and immunological approaches to the identification of leukemic cells. Subsequent chapters deal with preclinical approaches in tumor immunochemotherapy; mediation of immune responses to human tumor antigens with "immune" RNA; and the role of transfer factor in human cancer. This monograph will be of interest to oncologists and immunologists.

  • Regulatory Mechanisms of Carbohydrate Metabolism

    11th Meeting Copenhagen 1977
    • 1 Edición
    • Viggo Esmann
    • Inglés
    Regulatory Mechanisms of Carbohydrate Metabolism contains the proceedings of the 11th meeting of the Federation of European Biochemical Societies, held at Copenhagen in 1977. The symposium is attended by thousands of biochemists and their associates to present and discuss the regulatory mechanisms of carbohydrate metabolism. The compendium records the nine sessions of the symposium encompassing 30 chapters of various discussions on the regulatory mechanisms of carbohydrate metabolism. Topics on metabolism of pyruvate in animals; mechanism of insulin secretion; the role of pyruvate in the regulation of carbohydrate metabolism; and control of muscle glycogen metabolism by protein kinases and phosphates are covered. Ketogenesis and carbohydrate metabolism; factors controlling glucagon secretion; and energy homeostasis and the regulation of carbohydrate metabolism are discussed as well. Biochemists, chemists, physicians, pharmacologists, and students of medicine will find this book a good source on insight.

  • Protides of the Biological Fluids

    Proceedings of the Twenty-Fourth Colloquium, Brugge, 1976
    • 1 Edición
    • H. Peeters
    • Inglés
    Protides of the Biological Fluids contains the proceedings of the XXIVth Colloquium on Protides of the Biological Fluids held in Brugge, Belgium in 1976. Contributors explore relevant findings about protides of biological fluids and discuss topics such as pregnancy-associated proteins, carcino-fetal and carcinoplacental proteins, and molecular amplification. This volume consists of 151 chapters organized into three sections and begins with a discussion of the problems of specific placental and fetal proteins as well as the appearance of these proteins in maternal serum. The biochemistry and structure of human placental lactogen is considered together with its possible application in the diagnosis of abnormal pregnancy and the role of pregnancy specific proteins especially with regard to immunization during pregnancy. The next section focuses on oncofetal proteins, with particular reference to the biological significance of alpha-fetoprotein, its appearance during various types of cancer, and its increase in abnormal pregnancy. The isolation and properties of CEA and related antigens such as TPA, and the importance of their assay in early cancer detection as well as in follow-up studies of patients after surgery or therapy are described. The final section explores the use of molecular amplification in detection of trace amounts of proteins. It explains how radio-immunoassay, RIA, or ELISA can amplify a basic reaction between two molecules and increase its specificity as well as its limits of detection. This book will be of interest to scientists, students, and researchers working in the fields of biology and biochemistry.

  • Regulation of Secondary Product and Plant Hormone Metabolism

    FEBS Federation of European Biochemical Societies: 12th Meeting, Dresden, 1978
    • 1 Edición
    • M. Luckner + 1 más
    • Inglés
    Regulation of Secondary Product and Plant Hormone Metabolism contains the proceedings of the 12th Meeting of the Federation of European Biochemical Societies held in Dresden, Germany in 1978. The meeting provided a forum for discussing progress in understanding the regulation of the metabolism of secondary products and plant hormones. It shows that the processes regulating secondary metabolism are similar in lower and higher plants, and that the molecular basis of cell differentiation and specialization is uniform in all groups of living organisms. Comprised of 22 chapters, this volume begins with an overview of the interrelationships between secondary products and hormones in plants, followed by a detailed account of the effects of phenolic compounds on auxin biosynthesis and vice versa. The reader is then introduced to non-ribosomal biosynthesis of biologically active peptides; channelling of intermediates during the biosynthesis of cyanogenic glycosides; and intracellular distribution of flavonoids in glandular cells. Subsequent chapters explore the regulation of gene expression in secondary biosynthesis; inhibition of phenylalanine ammonia-lyase by cinnamic acid derivatives; novel inhibitors of phenylpropanoid metabolism in higher plants; and stage-specific phenylpropanoid metabolism during pollen development. This book will be of interest to biochemists and geneticists.

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