Saltar al contenido principal
Elsevier

Libros en Ciencias de la Vida

  • Animal Models of Disease Part E

    • 1 Edición
    • Volumen 203
    • Inglés
    Animal Models of Disease, Part E, Volume 203 in the Methods in Cell Biology series, presents significant advancements in understanding disease mechanisms through animal models. The book features chapters on timely topics such as characterizing tumor-infiltrating group 1 innate lymphoid cells in PyMT breast tumors and using zebrafish to unravel the molecular mechanisms of Alzheimer’s disease. The book also covers colitis mouse models and appropriate models for studying diabetes pathophysiology, demonstrating its comprehensive approach to current research.Additional sections cover evaluating polyglutamine protein aggregation in transgenic Caenorhabditis elegans models of Huntington's disease and studying tumor responses to radioimmunotherapy in ovarian cancer models. It also highlights the antimicrobial regime for gut microbiota depletion in mice and the biodistribution of metallic nanoparticles for lymphoma studies. This book is an essential resource for researchers seeking to explore disease mechanisms and therapeutic approaches through animal models.

  • Comprehensive Integrative Oncology

    • 1 Edición
    • Suzanna Zick + 1 más
    • Inglés
    Comprehensive Integrative Oncology is a vital resource for clinicians who seek to blend integrative therapies with conventional oncology care to enhance patient outcomes. This book, authored by experts in both conventional and integrative medicine, emphasizes a holistic approach to cancer treatment. It provides practical guidance on incorporating scientifically-backe... therapies like botanicals, supplements, mind-body practices, lifestyle changes, nutrition, and exercise into standard cancer care, all while prioritizing patient safety, prevention, and overall wellness. The book delves into the philosophy of integrative oncology, offers tools for practical application, and presents integrative strategies for cancer prevention and symptom management.Additiona... it explores the needs of special populations within oncology. It serves as an indispensable textbook for oncology researchers and practitioners who aim to provide holistic and patient-centered care.

  • Neurobiology of Type 2 Diabetes

    • 1 Edición
    • Shovit Ranjan + 2 más
    • Inglés
    The "Neurobiology of Type 2 Diabetes" delves into the intricate interplay between the nervous system and the development, progression, and management of Type 2 Diabetes. This comprehensive volume explores the often-overlooked neurological aspects of diabetes, offering a unique perspective on the disease. The purpose of this book is to bridge the gap between neuroscience and diabetes research, providing a consolidated resource that elucidates the complex relationship between the brain and metabolic regulation. By synthesizing the latest scientific findings, the book aims to offer researchers, clinicians, and students a deep understanding of how neural pathways influence glucose homeostasis, insulin sensitivity, and the emergence of diabetic complications.

  • Emerging Omics Technologies for Sustainable Agriculture

    • 1 Edición
    • Geerten W. Vuister + 3 más
    • Inglés
    Emerging Omics Technologies for Sustainable Agriculture provides a comprehensive overview of the transformative potential of advanced tools such as AI, genomics and proteomics to ensure future agricultural production.The integration of genomics, transcriptomics, proteomics, and metabolomics has advanced the understanding of plant and microbial systems and the application of this knowledge has enabled precision farming, optimizing crop yield and minimizing environmental impact. There are unprecedented opportunities to enhance crop yields, improve pest and disease management, to optimize resource utilization and to mitigate environmental impacts. Through the use of advanced data analytics, machine learning, and predictive modeling, researchers can decipher complex biological processes and develop innovative solutions for agricultural challenges.Emerging Omics Technologies for Sustainable Agriculture explores the advancements in AI-driven omics technologies, such as genome editing, transcriptomics, and phenomics, and their applications in crop improvement, soil health monitoring, and precision agriculture.

  • Autoimmune Encephalitis and Paraneoplastic Syndrome

    Current Knowledge and Updates
    • 1 Edición
    • Shitiz Sriwastava
    • Inglés
    Autoimmune Encephalitis and Paraneoplastic Syndrome: Current Knowledge and Updates provides an overview of the immune-driven disorders of the nervous system, particularly autoimmune encephalitis. By integrating case studies, flow charts, and clinical examples throughout, the book helps users navigate the complexities of autoimmune encephalitis. Sections also address demographic traits, tumor correlations, and outcomes, equipping readers with essential knowledge for diagnosis and management. With a strong focus on classifying these disorders, defining their pathogenesis and pathophysiology, and examining recent treatment guidelines, this book serves as a comprehensive guide for clinicians, neurologists, and researchers in neuroimmunology.

  • Lipids and Membranes: Detection by Imaging and Lipidomics

    • 1 Edición
    • Volumen 726
    • Inglés
    Lipids and Membranes: Detection by Imaging and Lipidomics, Volume 727 covers lipids, a chemically diverse set of biological molecules subject to rapid metabolism and transport. This dynamic behavior has motivated the development of methods across multiple disciplines for their detection and manipulation. Split into three parts, the chapters in this new release include Measurement of fatty acid esters of hydroxy fatty acids, Superresolution organelle imaging with lipophilic HIDE probes, Ultra-high resolution analysis of membrane lipids from 15N metabolically labeled mice, Superresolution lipid imaging with expansion microscopy, High-resolution phosphoinositide analysis in healthy versus disease cells, and much more.Additional chapters focus on Alkyne lipids as tracers of lipid metabolism, Imaging oxidative stress in biomembranes, Imaging the dynamics of phosphatidylinositol 4-phosphate metabolism, Lipidomics for studying sphingolipids in cell death, Non-invasive imaging of phosphoinositides with genetically encoded lipid biosensors, Profiling lipotypes at the single cell level in heterogenous populations, MS imaging of phosphoinositides, and much more.

  • Profiles of Drug Substances, Excipients, and Related Methodology

    • 1 Edición
    • Volumen 51
    • Inglés
    Profiles of Drug Substances, Excipients, and Related Methodology, Volume 51 provides comprehensive profiles of four pharmaceutical compounds: Vortioxetine, Rosuvastatin Calcium, Perindopril, and Ferulic Acid. In addition, it includes a review article concerning Drugs and Polymer Based Local Delivery Systems in the Treatment of Periodontal Diseases. Chapters in this new release include Vortioxetine: A Comprehensive Profile, Rosuvastatin Calcium: A Comprehensive Profile, Ferulic Acid: A Comprehensive Profile, Perindopril: A Comprehensive Profile, Drugs and Polymer Based Local Delivery Systems in the Treatment of Periodontal Diseases, Kinetic Exclusion Assay Technology: Theory, Experimental Aspects, and Applications in Concentration Measurements Across Diverse Fields, and more.No other book series provides this essential information as promptly and pertinently. Sections provide review articles and database compilations categorized into five primary domains: Physical Profiles of Drug Substances and Excipients; Analytical Profiles of Drug Substances and Excipients; ADME Profiles of Drug Substances and Excipients; Methodology Pertaining to the Characterization of Drug Substances and Excipients; and Methods of Chemical Synthesis.

  • Advances in Clinical Chemistry

    • 1 Edición
    • Volumen 131
    • Inglés
    Advances in Clinical Chemistry, Volume 131 in this ongoing series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics, including Advances in Volatile Organic Compound Biomarker Detection, 2D-DIGE proteomics, Interacting partners of Tau protein in Alzheimer’s disease, Biosensors for Detection of Autoimmune Disease, Small Molecule Biomarkers in Infectious Disease, and Diagnosis and Risk Factors in Pancreatogenic Diabetes. Each chapter is written by an international board of authors.

  • Live Biotherapeutics: Advancing Microbial Medicine

    • 1 Edición
    • Volumen 220
    • Inglés
    Microbial therapeutics are rapidly reshaping modern medicine, with live biotherapeutics emerging as a promising frontier. By harnessing the power of beneficial microbes, these innovative treatments offer new hope for conditions that resist conventional drugs, including metabolic disorders and antimicrobial-resist... infections. As the demand for safer, more effective alternatives grows, understanding this field becomes increasingly vital. The upcoming book, Live Biotherapeutics: Advancing Microbial Medicine, will provide a comprehensive and accessible overview of the science, applications, and future potential of live biotherapeutics in transforming healthcare.

  • Circulating Biomarkers for Diagnosis, Prognosis and Treatment Response Prediction in Cancer - Part B

    • 1 Edición
    • Volumen 399
    • Inglés
    Circulating Biomarkers for Diagnosis, Prognosis and Treatment Response Prediction in Cancer Patients, Part B delves into the crucial role of circulating biomarkers in cancer diagnosis and treatment monitoring. Specific chapters in this new release include Liquid biopsy approaches to capture minimal residual disease and therapy response in patients with early stage cancers, Identification of circulating biomarkers for cancer therapy-related cardiovascular toxicity, Extracellular Vesicles as Dynamic Biomarkers: Monitoring Therapeutic Responses and Drug Resistance in Cancer, and more.This comprehensive work explores the various types of biomarkers, their significance in early cancer detection, prognostication, and evaluation of therapeutic responses. It covers cutting-edge research on circulating tumor cells, cell-free DNA, exosomes, and other biomarkers that can revolutionize cancer management. Additionally, it discusses the challenges, advancements, and future prospects of utilizing circulating biomarkers in personalized cancer care.

  • Agricultural Applications of Earth Observation

    • 1 Edición
    • Peng Fu
    • Inglés
    Agricultural Applications of Earth Observation details the revolutionary impact of satellite and remote sensing technologies in enhancing agricultural practices. It bridges the knowledge gap by making advanced satellite and sensor data understandable and applicable, enabling readers to select the best tools for specific agricultural needs. Real-world case studies and practical examples demonstrate the successful implementation of Earth Observation technologies in agriculture, inspiring readers with tangible results and encouraging innovative thinking. Agricultural Applications of Earth Observation enables readers to apply Earth Observation technologies to enhance agronomical sustainability and contribute to more environmentally friendly practices. With detailed methodologies and a range of additional supplementary elements, the book equips readers with the knowledge and tools to drive the future of agriculture into a more sustainable era.

  • Neurobiology and Artificial Intelligence

    Medical, Social and Ethical Implications
    • 1 Edición
    • Luca Saba
    • Inglés
    Neurobiology and Artificial Intelligence: Medical, Social, and Ethical Implicationsexplores the dynamic intersection of neurobiology and artificial intelligence (AI),investigating the scientific, philosophical, and ethical implications of these rapidlyevolving fields. By blending cutting-edge research with thought-provoking discussions,this book aims to make complex topics accessible to an interdisciplinary audience,from researchers and upper graduate students eager to understand how AI andneuroscience shape our understanding of intelligence, creativity, learning, and thehuman condition.

  • Artificial Intelligence in Precision Drug Design, Volume 1

    Foundations and Core Techniques
    • 1 Edición
    • Khalid Raza
    • Inglés
    Artificial Intelligence in Precision Drug Design: Advanced Applications showcases how artificial intelligence (AI) is revolutionizing modern drug discovery and development. Building upon the foundational principles established in Volume 1, this book dives into real-world applications where AI accelerates innovation, enhances predictive accuracy, and enables breakthrough therapeutics. Featuring contributions from leading global researchers and practitioners, the book explores machine learning, deep learning, and network-based approaches applied to complex biomedical challenges. Key areas include AI driven drug repurposing, combination therapies, immunotherapy, vaccine design, quantum computing, and the integration of large language models in drug discovery. Additional chapters highlight predictive modeling using electronic health records, AI-powered medical imaging, and explainable AI for structure-based drug design. What sets this volume apart is its emphasis on practical impact, demonstrating how data, computation, and interdisciplinary collaboration converge to advance precision medicine. Designed for scientists, clinicians, educators, and students, it serves as both a comprehensive reference and a source of inspiration for leveraging AI to transform healthcare.

  • Agricultural Biostimulants for Mitigation of Salt, Drought, and Heat Stress

    • 1 Edición
    • M. Naeem + 1 más
    • Inglés
    Agricultural Biostimulants for Mitigation of Salt, Drought, and Heat Stress provides up-to-date information on sustainable strategies to enhance the resilience of agricultural crops under adverse environmental conditions. As part of the Biostimulants and Protective Biochemical Agents series, this volume focuses on high-impact challenges and emerging opportunities in crop stress management.Biostimul... represent a promising and effective approach to achieving sustainable agriculture. Widely regarded as renewable sources of plant nutrients, they can enhance crop productivity and improve soil health. Over the past decade, there has been growing interest in the use of diverse biostimulants—includ... plant growth-promoting fungi, rhizobacteria, seaweed extracts, and organic amendments—to increase nutrient use efficiency and boost plant tolerance to abiotic stresses.This book covers a range of key biostimulant categories such as bacteria, algae, plant growth regulators (PGRs), plant growth-promoting bacteria (PGPB), biochar, and other core approaches. It explores how specific biostimulants contribute to protecting and enhancing plant health and is the first comprehensive reference to focus exclusively on their role in safeguarding crop yields under salt, drought, and heat stress conditions.

  • Lipid Nanoparticles-Based mRNA Delivery System

    • 1 Edición
    • Raj Kumar
    • Inglés
    Lipid Nanoparticles-Based mRNA Delivery System offers a comprehensive exploration of lipid nanoparticles (LNPs), the most promising delivery vehicles for mRNA. The book consolidates current knowledge, identifies research gaps, and provides insights into the latest developments in LNP technologies, making it an essential resource for researchers, pharmaceutical developers, and clinicians at the forefront of mRNA therapeutics. Exploring the intricacies of LNP formulation, the book covers a wide range of topics, including the fundamental principles of lipid nanoparticles, design strategies for effective mRNA encapsulation, and the unique challenges associated with various routes of administration—such as intravenous, oral, transdermal, and intranasal delivery.The book also examines the therapeutic applications of lipid-based systems, particularly in vaccines and cancer immunotherapy, while addressing critical challenges like immunogenicity and regulatory considerations. Final sections provide a forward-looking perspective on future trends and innovations in lipid-based mRNA delivery systems, ensuring that readers are well-equipped to navigate this rapidly evolving field.

  • Mathematical Modeling and AI-Driven Computational Techniques for Epidemiology and Disease Dynamics

    • 1 Edición
    • Sayooj Aby Jose + 2 más
    • Inglés
    Mathematical Modeling and AI-Driven Computational Techniques for Epidemiology and Disease Dynamics offers a comprehensive exploration of innovative methodologies at the intersection of mathematics, biology, and medicine. This book delves into advanced mathematical modeling, artificial intelligence, and computational intelligence, providing essential tools for understanding and managing complex disease dynamics. Covering a wide range of topics, including fractional-order modeling, optimal control strategies, and privacy-preserving technologies, it addresses critical challenges in public health and healthcare systems. With contributions from leading experts, this volume bridges theoretical advancements and practical applications, making it an invaluable resource for researchers, healthcare professionals, and academics seeking interdisciplinary solutions to global health issues.

  • Cutting-Edge Nanocarrier-Based Strategies in the Management of Leukaemia

    • 1 Edición
    • Devesh U. Kapoor + 2 más
    • Inglés
    Cutting-edge Nanocarrier-Based Strategies in the Management of Leukaemia addresses the importance of nanocarriers in leukemia treatment. The book explores advancements in nanotechnology, highlighting therapies like siRNA, miRNA, and gene therapy that improve patient outcomes. Sections provide an introduction to leukemia, covering its epidemiology and risk factors, discuss innovative therapies and the use of various nanocarriers, such as polymeric nanoparticles, liposomes, dendrimers, and hydrogels, and discuss precision medicine, AI in leukemia care, and strategies to overcome treatment resistance. The book is enriched with tables, figures, and images, giving healthcare providers, including physicians, immunologists, oncologists, and pharmacists an invaluable resource on cutting-edge therapies.

  • Episodes in the History of Medical Science

    Discovery Meets Orthodoxy
    • 1 Edición
    • Anthony R. Rees
    • Inglés
    Episodes in the History of Medical Science: Discovery Confronts Orthodoxy highlights key moments in history where scientific and medical advances faced acceptance and rejection by the prevailing orthodoxy. This book places present-day disease protection in context by exploring significant medical and scientific theories, their success stories, challenges, and the frequent resistance to new ideas. It shows how acceptance of scientific discoveries often lags due to conservatism within the scientific community and broader socio-political and cultural influences. The book examines the origins of medical theory and practice, from the revolutionary ideas of Hippocrates and Galen to the rise of Islamic Medicine and the scholasticism of the Middle Ages. It covers the arrival of syphilis in Europe and the ensuing medical debates, the historical battle against smallpox through variolation and vaccination, and the skepticism faced by groundbreaking discoveries in the 19th and 20th centuries. Key topics include the gene debate, the thalidomide tragedy, the antibody revolution, and the paradigm shift in understanding stomach ulcers. The narrative also addresses the modern era's anti-vaccinationism and vaccine hesitancy, emphasizing the ongoing tension between scientific integrity and public acceptance. Episodes in the History of Medical Science: Discovery Confronts Orthodoxy is a valuable resource for medical professionals, researchers, historians, and students. It underscores the importance of scientific and medical integrity, the pursuit of truth, and validated scientific communication. By providing historical insights and examples of perseverance in the face of skepticism, this book offers valuable lessons for improving public health and understanding the dynamic journey of medical science.

  • Plant Proteins, Bioactive Peptides, and Healthy Foods

    Nutritional Properties, Functional Applications, and Processing Innovations
    • 1 Edición
    • Zhongjiang Wang + 4 más
    • Inglés
    Plant Proteins, Bioactive Peptides, and Healthy Foods: Nutritional Properties, Functional Applications, and Processing Innovations offers a comprehensive exploration of emerging and novel plant-based proteins, including soy, pea, walnut, quinoa, hemp, duckweed, oat and more, detailing nutritional properties, bioactive peptide generation, and the potential health benefits they offer for cardiovascular support, muscle recovery, and inflammatory conditions. By analyzing the interactions between proteins and other food components, such as fibers and lipids, the book also highlights the synergies that improve nutrition and digestion. The latest processing technologies, including fermentation and enzymatic hydrolysis, that enhance protein bioavailability are also detailed.Chapter experts highlight the challenges and opportunities in plant-based utilization, including limitations in sensory attributes, processing challenges and allergenicity, strategies for optimizing nutritional quality and functional properties, and future directions in research and industrial applications. Sustainable and efficient plant-protein production is also addressed. This book serves as a valuable guide for professionals in the food industry and researchers looking to innovate functional food products and nutraceuticals, contributing to the growing demand for sustainable, plant-based diets.

  • Translational Cardiothoracic Surgery

    • 1 Edición
    • Adam E.M. Eltorai
    • Inglés
    Translational research is essential to the advancement of medicine. This Cardiothoracic-speci... instructional guide to translational medical research serves as a practical, step-by-step roadmap for taking a biomedical device, potential therapeutic agent, or research question from idea through demonstrated clinical benefit. Fundamentally, the volume aims to help bridge the gap between current research and practice. Written by a team of expert medical, biomedical engineering, and clinical research experts in cardiothoracic surgery, this volume provides a clear process for understanding, designing, executing, and analyzing clinical and translational research within the field.

  • Inmunología

    • 10 Edición
    • David Male + 2 más
    • Español
    Nueva edición de uno de los textos de referencia en inmunología de nuestro portfolio en el que se abordan de forma equilibrada e integrada los conceptos pertenecientes a la inmunología básica y clínica. La estructura general de esta edición de Inmunología es la misma que la de la novena edición, Las secciones 1 y 2 describen el funcionamiento del sistema inmunitario. La sección 3 se ocupa de las respuestas inmunitarias contra los microorganismos patógenos (la función principal del sistema inmunitario), y las secciones 4 a 6 abordan aspectos de inmunología clínica, como las enfermedades autoinmunitarias, la inmunodeficiencia, los trasplantes, la inmunología tumoral y la hipersensibilidad. Todos los capítulos se han actualizado por completo e incluyen numerosos diagramas nuevos. Especial atención merecen los Caps. 17,18,20 y 22 por su profunda actualización en temas relativos a las nuevas vacunas de mRNA, inmunización pasiva, autoinmunidad, nuevos anticuerpos y nuevas terapias celulares y los nuevos descubrimientos a raíz de la epidemia de Covid. Las secciones de razonamiento crítico que siguen a cada capítulo requieren la comprensión del material presentado y de las implicaciones en un entorno de laboratorio o clínico, y sirven como base para el debate en el aula. Otro importante instrumento pedagógico son los resúmenes que recogen los puntos clave de cada capítulo, así como los numerosos esquemas, diagramas y figuras. La nueva edición ofrece contenido adicional online en español a través de la plataforma e-book+. Incluye apartados, tablas y figuras adicionales, así como una colección de 15 videos.

  • Microglial Aging

    Basic, Translational and Clinical Advances
    • 1 Edición
    • Marie-Eve Tremblay
    • Inglés
    Microglial Aging: Basic, Translational, and Clinical Advances explores groundbreaking research on microglial function in the context of aging. This comprehensive resource delves into the physiological roles of microglia, the effects of aging on their structure and activity, and their significance in age-related neurodegenerative diseases. With insights from basic, translational, and clinical studies, it provides a thorough understanding of microglial health and its impact on aging. The book discusses how lifestyle choices can enhance microglial functions and prevent neurodegenerative diseases. It covers both pharmacological and non-pharmacological approaches, such as the ketogenic diet, cannabinoids, psychedelics, and non-invasive vagal nerve stimulation.This text is invaluable for researchers and clinicians focused on improving the quality of life for an aging population.

  • Comprehensive Chemistry and Biology of Coumarins Scaffold

    • 1 Edición
    • Shehryar Hameed + 2 más
    • Inglés
    Comprehensive Chemistry and Biology of Coumarins Scaffold covers detailed methods and protocols to synthetize Coumarin derivatives and different applications and future perspectives for these compounds. Coumarin-Based Scaffolds plays an important role in organic, bioorganic, and medicinal chemistry as they act as a bridge between chemistry, life sciences, and biochemical investigations. Coumarin is an important scaffold for designing, generating a wide variety of chemical libraries and drug-like candidates to obtain desired therapeutic and pharmacological properties. Specific functional groups are covered as well as the synthesis of bioactive compounds against specific pathological conditions.The discovery of new coumarin-based drug candidates during the last decades has been covered to assist the pharmaceutical, bioorganic and medicinal chemists for their further research on coumarin-based molecules.

  • Advances in Food and Nutrition Research

    • 1 Edición
    • Volumen 118
    • Inglés
    Advances in Food and Nutrition Research, Volume 118 provides the latest advances on nanoformulations that can be used in the food industry, including chapters that cover important topics such as Nanoformulation Used In The Food Industry, Advances in Rapid On-Site Detection Techniques for Food Safety and Authenticity, Utilizing Artificial Intelligence to Enhance Sustainable High-Quality Food Production: Current State, Challenges, and Future Directions, Advances in High Hydrostatic Pressure Processing of Fruit and Vegetable Juicesm Functionality, Health Benefits, and Applications of Fish-Derived Hydrolysates and Peptides, and more.Additional chapters explore Maximizing the utilisation of seafood resources, A novel cooking technique for seafood: sous-vide, and Vegetable oils as a source of omega-3 fatty acids – transgenic vegetable oil.

  • Hematological Insights and Clinical Implications of Platelet Functions in Lymphatic Filariasis

    • 1 Edición
    • Jyotsna Kailashiya
    • Inglés
    Hematological Insights and Clinical Implications of Platelet Functions in Lymphatic Filariasis is a groundbreaking resource that delves into the impact of filarial parasites on platelet functions in humans. This comprehensive work explores the intricate signaling and immunological pathways affected by these interactions, filling a significant gap in the existing literature. The book is particularly valuable for researchers, scientists, and clinicians involved in the management and study of lymphatic filariasis, commonly known as elephantiasis; and also human platelets. With limited prior information on the interplay between human platelets and filarial parasites, this text offers a fresh perspective that could enhance patient management strategies. By understanding these interactions, healthcare professionals may unlock new avenues for effective treatment and prevention of lymphatic filariasis. This book is essential for anyone looking to deepen their understanding of the disease and contribute to its potential elimination.

  • Mitochondria and Cancer

    From Basic Science to Clinical Applications – Understanding Pathogenesis, Therapy Resistance, and Disease Relapse
    • 1 Edición
    • Farzad Taghizadeh-Hesary + 3 más
    • Inglés
    Mitochondria and Cancer: From Basic Science to Clinical Applications—Underst... Pathogenesis, Therapy Resistance, and Disease Relapse offers comprehensive perspectives about the role of mitochondria in cancer biology and treatment. This book integrates fundamental scientific knowledge with clinical relevance, presenting recent findings that will engage oncology researchers and provide valuable recommendations for cancer prevention and prognosis. In response to the rising global cancer incidence, this book serves as a comprehensive guide to mitochondrial metabolism in oncology, furthering cancer study and management. It explores a wide range of topics that highlight the multifaceted role of mitochondria in cancer, including tumor microenvironment, cancer stem cells, microbiota, resistance mechanisms, mitochondria-enhanci... strategies, and targeted therapies. It includes technical details, research findings, and discussions on the implications of mitochondrial research in cancer treatment and management. Its distinguishing aspects include its comprehensive coverage and diverse perspectives from global experts, providing a well-rounded view of current research.

  • ATP

    From Neurotransmission to Cancer Therapy
    • 1 Edición
    • Ronald Sluyter + 5 más
    • Inglés
    ATP: From Neurotransmission to Cancer Therapy delivers a comprehensive discussion of extracellular ATP biology and its communication role in both homeostasis and pathologic states. It explores the function of ATP across the nervous, sensory, musculoskeletal, cutaneous cardiovascular, pulmonary, gastrointestinal, urinary, reproductive, exocrine, haematopoietic and immune systems. The book considers ATP in the context of various disease states, including cardiovascular, respiratory, psychiatric, inflammatory and neurodegenerative disorders, as well as pain and sensory disorders, infectious diseases, and cancer. ATP in humans is explored alongside other species, including rodents, fish, and plants. This is the latest volume in the “Molecular Mediators in Health and Disease” series. With contributions from specialists across pharmacology, physiology, biophysics, biochemistry, immunology, anatomy, molecular biology, therapeutics, and other critical fields, this volume provides a broad and detailed overview of ATP which will be helpful to researchers working in these areas and beyond.

  • Marine Microbial Products

    Applications and Opportunities
    • 1 Edición
    • Sesan Abiodun Aransiola + 2 más
    • Inglés
    Marine Microbial Products: Applications and Opportunities delves into the extensive world of marine microbes, an assemblage of organisms that contain a broad array of bioactive chemicals. Written and edited by a diverse team of environmental microbiologists, this book provides readers with a foundational understanding of marine microbial taxa, the products that may be synthesized from these organisms, technological innovations, and future directions of research. Chapters collate the most current research in healthcare, sustainability, and commercial production, presenting readers with the latest information on antibiotics, antivirals, anticancer therapeutics, immunosuppressive chemicals, bioremediation, food processing, biofertilizers, biopesticides, cosmetics, pigments, probiotics, and functional foods.The book is structured for accessibility to academic and professional audiences, spanning a variety of sectors. It is an indispensable resource for students, professors, researchers, and industry professionals in biology, biotechnology, sustainable development, food, healthcare sciences, and adjacent industries.

  • Advances in Agronomy

    • 1 Edición
    • Volumen 196
    • Inglés
    Advances in Agronomy, Volume 196, the latest release in this leading reference on agronomy, contains a variety of updates and highlights new advances in the field, each written by an international board of authors.

  • Immuno-oncology and Immunotherapy Part G

    • 1 Edición
    • Volumen 202
    • Inglés
    Immuno-oncology and Immunotherapy, Part G, Volume 202 in the Methods in Cell Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including In situ imaging of pulmonary invariant Natural Killer T cells in precision cut lung slices, Immunofluorescent microscopy to quantify and characterize chromosomal instability, Spatial techniques for understanding the tumor microenvironment, Very high-flex immunophenotyping using co-linear cytofluorometric evaluation, Large-scale CRISPR-Cas9 screens to define regulators of immune checkpoint biology, Assessment of cytoplasmic dsDNA for cellular immunogenicty, and much more.Additional sections cover Harmonization of a multiparametric flow cytometry panel for immunological monitoring on PBMC and whole blood samples: a real-life example, Quantitative assessment of arterial remodeling from confocal microscopy image analysis of the mid-gestation mouse decidua, Phenotypic characterization and function of tumor infiltrating and peripheral B cells in cancer patients, Methodological Advances to analyze Cancer-Associated Fibroblast-derived ECM effects on Macrophage Polarization, and many other topics that will be of interest to readers.

  • Endocrine and Metabolic Emergencies, An Issue of Endocrinology and Metabolism Clinics of North America

    • 1 Edición
    • Volumen 55-1
    • George C. Willis + 1 más
    • Inglés
    In this issue of Emergency Medicine Clinics, guest editors Drs. George Willis and Bennett A. Myers bring their considerable expertise to the topic of Endocrine and Metabolic Emergencies. Endocrine and metabolic emergencies, both those that are commonly encountered in day-to-day emergency medicine and those that are rarely seen, can result in serious complications that can be life-threatening if not recognized, diagnosed, and appropriately managed. In this issue, top experts in the field cover key topics such as diabetic ketoacidosis; hyperosmolar hyperglycemic state; disorders of sodium and potassium; hypoglycemia; and more.

  • Tic Disorders and Tourette Syndrome

    • 1 Edición
    • Volumen 215
    • Christos Ganos + 1 más
    • Inglés
    Tic Disorders and Tourette Syndrome is an essential resource that delves into the clinical aspects, treatments, and ongoing research related to tic disorders and Tourette syndrome. It covers a range of topics from primary to secondary and functional tics, providing differential diagnosis. The book is designed to offer foundational knowledge to neurologists, psychiatrists, neuropsychiatrists, and psychologists, while also catering to the needs of advanced readers. In addition to clinical presentations, the book discusses the epidemiology, etiology, and pathophysiology of tics, along with common neuropsychiatric comorbidities such as obsessive-compulsive disorder, ADHD, mood disorders, and intermittent explosive disorder. The volume also includes treatment options and clinical scales to evaluate tics, illustrated with video accompaniments and animal models.

  • Aquatic Waste Valorization

    Innovative Approaches and Sustainable Strategies
    • 1 Edición
    • Piyush Kashyap + 2 más
    • Inglés
    Aquatic Waste Valorization: Innovative Approaches and Sustainable Strategies is a comprehensive guide for researchers and practitioners in food and environmental sciences, focusing on the critical intersection of waste management and sustainability within the aquatic food industry. The book explores the multifaceted dimensions of aquatic food industry waste, from its chemical composition and economic implications to a thorough introduction of valorization techniques for the use in functional food products and nutraceuticals. It covers emerging methodologies—includ... physical, chemical, and enzymatic processes—as well as approaches such as microbial conversion and nanotechnology, all aimed at transforming waste into valuable resources.In addition, it discusses the recovery of valuable components such as proteins, lipids, and bioactive compounds, highlighting their applications across various industries, including biofuels, bioplastics, and functional food ingredients. Through practical applications, it not only addresses the pressing issue of waste management but also presents innovative strategies to bolster both environmental and economic sustainability. Concluding sections examine global policies and regulations shaping the future of aquatic waste valorization.

  • Connected Diagnoses

    IoT, Healthcare, and Digital Forensics
    • 1 Edición
    • Keshav Kaushik + 1 más
    • Inglés
    Connected Diagnoses: IoT, Healthcare, and Digital Forensics investigates the complex intersection of IoT, healthcare, and digital forensics. The book explores the intricate relationships between these fields, with a focus on cybersecurity, patient data ethics, and challenges in IoT investigations. It advances knowledge on leveraging IoT securely to enhance patient care and digital forensic analysis, providing significant insights from experts along with practical guidance for those operating at the crossroads of these critical disciplines. The book helps professionals grasp, adapt to, and capitalize on the interconnected nature of emerging technologies to ensure ethics, security, and safety. Users will find this to be a comprehensive resource that benefits researchers and practitioners who seek to understand the convergence of medical technology, interconnected devices, and digital forensics.

  • Handbook of Functional Foods

    Techniques, Analytics and Health Benefits
    • 1 Edición
    • Pradeep Kumar + 2 más
    • Inglés
    Handbook of Functional Foods: Techniques, Analytics and Health Benefits provides a comprehensive overview of the extraction and analytical identification techniques of foods’ bioactive components for health and well-being while looking at metabolism, sensory, and safety components. This book reviews, in detail, how functional foods have the potential to drive innovation in the food industry, creating a broad range of healthier and more personalized food options. From emerging extraction and extrusion techniques for the creation of fiber-rich snacks to the synergistic effects of pro- and prebiotics on gut health, readers will come away with an advanced and fresh understanding of necessary insights.

  • Cushing Syndrome

    History, Diagnosis and Treatment
    • 1 Edición
    • Constantine A. Stratakis
    • Inglés
    Cushing Syndrome: History, Diagnosis, and Treatment is written by top experts on the latest in genetics, molecular advances, and the diagnosis and treatment of Cushing syndrome. The book takes a historical approach to discuss the tremendous and unprecedented research development for this rare condition and includes information on recently approved treatments. It attempts to provide information on most issues surrounding Cushing syndrome and how to deal with its complications, the widening understanding of functional hypercortisolemia and other causes of endogenous cortisol production and its old and new treatment modalities, from pituitary to adrenal tumors, ectopic ACTH production, subclinical, cyclical Cushing syndrome, to aging and metabolic syndrome.The book has a section dedicated to our patients with the patients’ experiences, which will add to the outcome research presented by the physicians. This is a must have reference for scientists and researchers with the latest information in diagnosing and treating this difficult-to-diagnos... and difficult-to-treat condition and gives the clinician, a patient-centric approach to communicate with this particular group of patients.

  • Nanotechnology-Based Innovations in Chronic Obstructive Pulmonary Disease (COPD) Treatment and Management

    • 1 Edición
    • Harish Dureja + 5 más
    • Inglés
    Nanotechnology-Based Innovations in Chronic Obstructive Pulmonary Disease (COPD) Treatment and Management explores innovative drug delivery systems utilizing nanotechnology to revolutionize the treatment and management of COPD. By presenting the latest advancements in nanotechnologies—inc... polymeric nanoparticles, liposomes, and theranostic nanoparticles—this volume aims to enhance patient outcomes, alleviate symptoms, and improve lung function, thereby addressing the urgent need for more effective therapies. Structured to cater to a diverse audience, from beginners to advanced researchers, this comprehensive text begins with an overview of COPD, its epidemiology, and current limitations in treatment. The core chapters explore a wide range of nanotechnological applications for diagnosis and disease management, including cutting-edge topics such as nano-immunotherapy and green nanotechnology. Each chapter was developed by a multidisciplinary team of experts from academia and industry, ensuring a comprehensive approach that integrates insights from pharmaceutical sciences, respiratory health, and bioinformatics. Nanotechnology-based Innovations in Chronic Obstructive Pulmonary Disease (COPD) Treatment and Management not only fills a critical gap in COPD literature but also serves as an invaluable resource for researchers, clinicians, and students alike. It promises to be a definitive guide on how innovative drug delivery systems can transform COPD care, paving the way for future advancements in respiratory health management.

  • Natural Product Drug Discovery

    Highly Anticipated Natural Molecules
    • 1 Edición
    • Ning Li + 1 más
    • Inglés
    Natural Product Drug Discovery: Highly Anticipated Natural Molecules, a new volume in the Drug Discovery Opinion series, provides a comprehensive examination of the role of natural products in innovative drug development. The book addresses the significant challenges that highly active natural molecules face in the drug development process, including issues related to bioavailability and potency. Sections present analyses of various classes of natural products, including polysaccharides, volatile oils, and diterpenoids, exploring their chemical properties, biological activities, and potential clinical applications. Each chapter, written by leading experts, offers insights into structural modification techniques, naturally sourced inhibitors, and the application of green biomanufacturing strategies.It will serve as an essential resource for researchers, pharmacologists, and industry professionals involved in natural product drug discovery. Readers will find the necessary information to navigate the complexities of the field, emphasizing the integration of traditional knowledge with modern scientific approaches. Through a thorough understanding of these natural compounds, this book aims to contribute to the advancement of therapeutic innovations in pharmacotherapy.

  • Design and Applications of Cell-Free Systems Part B

    • 1 Edición
    • Volumen 219
    • Inglés
    Design and Applications of Cell-Free Systems, Part B, Volume 219 offers the latest information on cell free systems for the expression of transmembrane proteins, enzymes, proteins, therapeutics, vaccines, and uses in the biotransformation, translational modification, self-assembly of nano-biomaterials, and in synthetic biology design, challenges, and opportunities. It will help students, researchers, scientists, clinicians, stakeholders, policymakers, and practitioners understand cell-free systems and their applications in many areas. The book represents an important component in the field of biochemistry, duly acknowledging the pioneering effort made by Nobel laureate Eduard Buchner for discovery of fermentation in yeast cell extracts (YCE).CFS requires core molecular machinery, including RNA polymerase, translational apparatus (ribosomes, tRNA synthases, and translation factors), energy-generating molecules, and their cofactors, substrates, and DNA or plasmid templates for obtaining desired products. CFS is a simple, rapid, and sensitive platform, which is devoid of membrane-bound barriers, yet contains all the mandatory substrates, biomolecules, and machineries required for the synthesis of the desired proteins.

  • Molecular Horticulture & Advances in Production System Technology

    • 1 Edición
    • Volumen 117
    • Inglés
    This volume offers a comprehensive overview of cutting-edge developments in horticultural science. This authoritative collection features expert reviews on the molecular genetics and genomics of key species, including faba bean, tomato, celery, lily, and broccoli, elucidating the mechanisms behind yield, quality, and bioactive compounds. The volume also explores innovative and sustainable cultivation techniques, with in-depth analyses of controlled environment agriculture for leafy greens, the use of organic substrates, and the sensory implications of sustainable practices for Brassica oleracea. Crucial insights into the molecular control of pre- and post-harvest traits, this essential text provides researchers, students, and professionals with a forward-looking synthesis of modern horticultural science and its practical applications.

  • Brain Energy Metabolism in Alzheimers Disease - Part A

    • 1 Edición
    • Volumen 186
    • Inglés
    International Review of Neurobiology, Volume 186 presents the latest developments in the field, with chapters written by an international board of authors. This volume offers a broad overview of current research and perspectives in neurobiology, serving as a valuable reference for researchers, clinicians, and students interested in understanding advances across diverse areas of the discipline.

  • Recent Advances in Bioelectromagnetism and Subtle Energies

    Implications for Health and Disease
    • 1 Edición
    • Jan Martel
    • Inglés
    Recent Advances in Bioelectromagnetism and Subtle Energies: Implications for Health and Disease explores the new findings and emerging concepts in the fields of electromagnetism and human health. This book examines a range of topics from a biophysical and holistic perspective, including the effects of native and manmade electromagnetic fields on living organisms, the role of oxygen in cellular energy production, the intricacies of the human biofield, coherence in cellular and human health, quantum biology phenomena, the history and evolution of electrosensitivity, the development of electromagnetic hygiene, and promising healing modalities. Each chapter provides key insights about the biological effects of electromagnetic fields and their impact on human health and disease development, providing an ideal reference for scientists and readers interested in the recent advances in these areas.

  • How to Develop Robust Scale-up Strategies for Complex Injectable Dosage Forms

    From Bench to the Clinics
    • 1 Edición
    • Neelam Poonia + 2 más
    • Inglés
    How to Develop Robust Scale-up Strategies for Complex Injectable Dosage Forms: From Bench to the Clinics provides a comprehensive roadmap for transitioning complex injectable formulations from the laboratory to clinical applications. Offering an exploration of various complex injectables, including liposomal dosage forms, nanoparticles, and microspheres, this book delves into dosage form design, excipient selection, stability studies, and optimization techniques. The book examines manufacturing technologies such as aseptic processing, sterile filtration, and lyophilization, and their applications in producing complex injectables. Discussions on quality control measures, analytical techniques, and quality assurance practices are provided to ensure consistent quality and purity throughout the manufacturing process.Readers will benefit from the expert knowledge and practical insights shared by industry professionals and leading researchers, including successful examples of marketed complex injectables. Highlighting best practices and regulatory requirements, this book offers a comprehensive overview of the guidelines for the development, manufacturing, and commercialization of complex injectables. Ideal for pharmaceutical scientists, formulation developers, and regulatory professionals, this book is a valuable resource for anyone involved in the scale-up and commercialization of complex injectable dosage forms.

  • Simulating Protein Folding in Variable Environmental Conditions

    Transformation from Globular Proteins to Amyloids
    • 1 Edición
    • Irena Roterman-Konieczna
    • Inglés
    Simulating Protein Folding in Variable Environmental Conditions: Transformation from Globular Proteins to Amyloids delves into the effects of external conditions upon the protein folding process. The book considers how this can lead to amyloid formation and why proteins fold the way they do. It presents the fuzzy oil drop model (FOD-M), which enables the measurements of external factors influencing the folding process and considers changed external conditions as the source for the misfolding process. Sections provide an introduction to amyloid transformation and outline the hypothesis of the model simulation before considering the role of environmental factors, including the water environment and membrane environment. This book is a useful resource for researchers interested in investigating protein folding across molecular biology, structural biology, biochemistry, computational biology and related fields.

  • Antibiotic Resistance and Nanotherapy

    • 1 Edición
    • Awanish Kumar + 1 más
    • Inglés
    Antibiotic Resistance and Nanotherapy is a comprehensive guide that explores an interdisciplinary approach to address the pressing issue of antibiotic resistance and explores the possibility of nanotherapy as a cutting-edge strategy to treat illnesses that are resistant to antibiotics, employing nanoparticles to target and kill bacteria selectively without damaging healthy cells. It details the underlying mechanisms of drug resistance in intracellular and extracellular pathogens and explores the latest advancements in nanotechnology, including the development of innovative nanomaterials and delivery systems that can be utilized to combat antibiotic-resistant infections. This book also discusses the ethical and practical challenges associated with implementing nanotherapy for bacterial resistance. Featuring contributions from experts in the field, this book is an essential resource for researchers, medical professionals, and policymakers seeking to understand and tackle the immediate threat posed by antibiotic resistance.

  • Evolution of Nervous Systems

    • 3 Edición
    • Jon H. Kaas + 1 más
    • Inglés
    Evolution of Nervous Systems, Third edition Four-volume set includes wholly new content, all chapters from the previous edition have been thoroughly updated, and the addition of brand new contributions by leading experts. Each of the volumes has been carefully restructured to offer expanded coverage of non-mammalian taxa, mammals, primates and the human nervous system. The basic principles of brain evolution are discussed, as well as mechanisms of change, which involve gene expression and altered courses of embryonic development. The reader can select from chapters on highly specific topics as well as those providing an overview of current thinking and approaches. This timely new edition of Evolution of Nervous Systems is a unique major reference work, offering the gold standard for those interested in evolution and in nervous systems.

  • How Sex and Gender Impact Clinical Practice

    An Evidence-Based Guide to Patient Care
    • 2 Edición
    • Marjorie R. Jenkins + 1 más
    • Inglés
    How Sex and Gender Impact Clinical Practice: An Evidence-Based Guide to Patient Care, Second Edition, is an essential resource for primary care clinicians seeking to integrate sex and gender differences into their practice. This edition emphasizes the unique framework that assists practitioners in providing personalized care. It aligns sex and gender medicine with precision medicine, helping healthcare providers attract patients who value clinicians that understand the nuances of sex and gender in healthcare.How Sex and Gender Impact Clinical Practice: An Evidence-Based Guide to Patient Care, Second Edition, includes updates on the evidence-based information on disease prevalence, diagnosis, testing, and treatment, as well as a new chapter on the sex and gender aspects of pain. Each chapter reflects how sex and gender impact disease presentation, physical examination, testing, treatment, and clinical decision-making.

  • Seaweed in Health and Disease Prevention

    • 2 Edición
    • Joël Fleurence + 1 más
    • Inglés
    Seaweed in Health and Disease Prevention, Second Edition updates knowledge on the therapeutic and functional activities related to algae and their compounds. The book includes a new chapter on the use of seaweed and seaweed products in the current war against viral-based exposures, a result of the massive research effort stemming from the global Covid Pandemic, along with the improvement of the nutritional value of algae via enzymatic or fermentation treatments. These treatments are at the origin of the production of oligosaccharides, presenting interesting biological activities for the human microbiota.Chapter updates on seaweed’s biochemical characteristics such as proteins, lipids, and polysaccharides are also addressed.

  • Primary Aldosteronism: Physiopathology and Diagnosis

    • 1 Edición
    • Volumen 130
    • Inglés
    Primary Aldosteronism: Physiopathology and Diagnosis, Volume 130 focuses on the physiopathology and diagnosis of primary aldosteronism, covering some important topics such as Aldosterone: synthesis and regulation, Pathophysiology of primary aldosteronism, Prevalence of primary aldosteronism and screening indications, Clinical manifestations of primary aldosteronism and cardiometabolic risk, Diagnosis of primary aldosteronism: renin activity, renin concentration and aldosterone/renin ratio, Diagnosis of primary aldosteronism confirmatory test, Diagnosis of Primary Aldosteronism: Novel Workup Strategies and Biochemical Tools, and much more. Additional sections cover Genetics in primary aldosteronism, Low-renin hypertension, Adrenal venous sampling interpretation and other diagnostic lateralization tools in PA, and Aldosterona & Cortisol cosecretion.

  • Decoding Plant–Environment–Microbiome Interactions in Stress-Resilient Agriculture

    • 1 Edición
    • Asfa Rizvi + 4 más
    • Inglés
    Decoding Plant–Environment–Mi... Interactions in Stress-Resilient Agriculture delivers both foundational understanding and forward-looking perspectives on the rapidly advancing field of phytomicrobiome research. Showcasing the unique advantages of microbial partnerships in stressed soils, the book explores how optimizing plant–microbiome interactions can transform crop productivity and sustainability.Focus... on the phytomicrobiome’s diverse components—including root-associated microbiota, plant growth-promoting rhizobacteria, endophytes, phosphate-solubilizi... microorganisms, arbuscular mycorrhizal fungi, and actinomycetes—the volume reveals how these microbial networks enhance plant stress tolerance, rehabilitate degraded or contaminated soils, and sustain yields under adverse conditions.Harnessin... these natural bioresources effectively requires an integrated understanding of the complex crosstalk between plants and their associated microbes, from molecular signaling to ecological mechanisms. Drawing on insights from internationally recognized scientists and leading academicians, this book consolidates cutting-edge research and emerging innovations, providing readers with the knowledge needed to advance stress-resilient and environmentally sustainable agriculture.

Temas relacionados