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Elsevier

Libros en Ciencias de la Vida

  • The Ecology and Biology of Nephrops Norvegicus

    • 1 Edición
    • Volumen 64
    • Inglés
    Advances in Marine Biology has been providing in-depth and up-to-date reviews on all aspects of marine biology since 1963 -- over 40 years of outstanding coverage! The series is well known for its excellence of reviews and editing. Now edited by Michael Lesser (University of New Hampshire, USA), with an internationally renowned Editorial Board, the serial publishes in-depth and up-to-date content on a wide range of topics that will appeal to postgraduates and researchers in marine biology, fisheries science, ecology, zoology, and biological oceanography.

  • Profiles of Drug Substances, Excipients, and Related Methodology

    • 1 Edición
    • Volumen 38
    • Harry G. Brittain
    • Inglés
    Volumes in this widely revered series present comprehensive reviews of drug substances and additional materials, with critical review chapters that summarize information related to the characterization of drug substances and excipients. This organizational structure meets the needs of the pharmaceutical community and allows for the development of a timely vehicle for publishing review materials on this topic. The scope of the Profiles series encompasses review articles and database compilations that fall within one of the following six broad categories: Physical profiles of drug substances and excipients; Analytical profiles of drug substances and excipients; Drug metabolism and pharmacokinetic profiles of drug substances and excipients; Methodology related to the characterization of drug substances and excipients; Methods of chemical synthesis; and Reviews of the uses and applications for individual drug substances, classes of drug substances, or excipients.

  • Viruses in Food and Water

    Risks, Surveillance and Control
    • 1 Edición
    • N Cook
    • Inglés
    Viruses can be highly infectious and are capable of causing widespread disease outbreaks. The significance of viral pathogens in food and waterborne illness is increasingly being recognised and viruses transferred by these routes are important areas of research. Viruses in food and water reviews the risks, surveillance and control of food and waterborne viral disease.Part one provides an introduction to food and environmental virology. Part two goes on to explore methods of detection, surveillance and risk assessment of viruses in food and water; it includes chapters on molecular detection of viruses in foods and food processing environments, quality control in the analytical laboratory, and quantitative risk assessment for food and waterborne viruses. Part three focuses on virus transmission routes and control of food and water contamination. It contains chapters on fresh produce, shellfish and viral presence, and control methods in waste water and sewage. Finally, part four highlights particular pathogens including norovirus, hepatitis A and emerging zoonotic viruses.Viruses in food and water is a standard reference book for microbiologists in academia, analytical labs and the food and water treatment industries, as well as environmental health professionals and researchers working on foodborne viruses.

  • Pattern Formations and Oscillatory Phenomena

    • 1 Edición
    • Shuichi Kinoshita
    • Inglés
    Patterns and their formations appear throughout nature, and are studied to analyze different problems in science and make predictions across a wide range of disciplines including biology, physics, mathematics, chemistry, material science, and nanoscience. With the emergence of nanoscience and the ability for researchers and scientists to study living systems at the biological level, pattern formation research has become even more essential. This book is an accessible first of its kind guide for scientists, researchers, engineers, and students who require a general introduction to this research area, in order to gain a deeper analytical understanding of the most recent observations and experiments by top researchers in physics. Pattern Formations describes the most up-to-date status of this developing field and analyzes the physical phenomena behind a wide range of interesting topics commonly known in the scientific community. The study of pattern formations as a research field will continue to grow as scientists expand their understanding of naturally occurring patterns and mimic nature to help solve complex problems. This research area is becoming more highly recognized due to its contributions to signal processing, computer analysis, image processing, complex networks development, advancements in optics and photonics, crystallography, metallurgy, drug delivery (chemotherapy) and the further understanding of gene regulation.

  • Ascaris

    The Neglected Parasite
    • 1 Edición
    • Celia Holland
    • Inglés
    This book tackles a number of different perspectives concerning the parasitic helminth Ascaris, both in animals and in humans and the disease known as ascariasis. It seeks to identify interesting, exciting and novel aspects, which will interest readers from a broad range of disciplines.Over a quarter of the world's population are infected with the human roundworm, and the equivalent in pigs is equally ubiquitous. Both contribute to insidious and chronic nutritional morbidity, and this has been quantified, in humans, as disability adjusted life years approximating 10.5 million. Ascaris larvae develop in host parenteral tissues, and the resultant pathology has been condemnation. Ascariasis, despite its staggering global prevalence and the sheer numbers of people it infects, remains a classic neglected disease. However, renewed interest in the consequences of early infection with worms from the perspective of immune modulation, co-infections and the development of allergy further enhances the relevance of these parasites.

  • Oligomerization in Health and Disease

    • 1 Edición
    • Volumen 117
    • Inglés
    This special volume of Progress in Molecular Biology and Translational Science focuses on oligomerization in health and disease.

  • Embodiment and Epigenesis: Theoretical and Methodological Issues in Understanding the Role of Biology within the Relational Developmental System

    Part B, Ontogenetic Dimensions
    • 1 Edición
    • Volumen 45
    • Inglés
    Volume 45 of Advances in Child Development and Behavior includes chapters that highlight some the most recent research in the area of embodiment and epigenesis.A wide array of topics are discussed in detail, including multiple trajectories in the developmental psychobiology of human handedness and the integration of culture and biology in human development. Each chapter provides in-depth discussions, and this volume serves as an invaluable resource for developmental or educational psychology researchers, scholars, and students.

  • Genetically Modified Food Sources

    Safety Assessment and Control
    • 1 Edición
    • Victor Tutelyan
    • Inglés
    Genetically Modified Food Sources reports detailed results of studies on the medical and biological safety of 14 species of genetically modified plant-derived organisms (GMOs). The authors focus on issues in GMO production and world output, specifically the basic legislative regulations of modern biotechnology in the Russian Federation. Also covered are international approaches to the medical and biological assessment of safety and control of the food produced from genetically modified organisms. A special chapter is devoted to the problem of informational coverage of novel biological technologies.Previou... available only in a 2007 Russian-language edition published by the Russian Academy of Medical Sciences, this English translation has been completely revised and updated to include the latest developments in regulations and human and animal safety assessment practices.The book is addressed to a wide community of specialists working in the fields of food science, plant genetics, and food safety as well as medicine and biology. Students and postgraduates focusing on the problems of modern biotechnology and biological safety will find it a valuable guide to these topics.

  • Cellular Migration and Formation of Neuronal Connections

    Comprehensive Developmental Neuroscience
    • 1 Edición
    • John Rubenstein + 1 más
    • Inglés
    The genetic, molecular, and cellular mechanisms of neural development are essential for understanding evolution and disorders of neural systems. Recent advances in genetic, molecular, and cell biological methods have generated a massive increase in new information, but there is a paucity of comprehensive and up-to-date syntheses, references, and historical perspectives on this important subject. The Comprehensive Developmental Neuroscience series is designed to fill this gap, offering the most thorough coverage of this field on the market today and addressing all aspects of how the nervous system and its components develop. Particular attention is paid to the effects of abnormal development and on new psychiatric/neurolog... treatments being developed based on our increased understanding of developmental mechanisms. Each volume in the series consists of review style articles that average 15-20pp and feature numerous illustrations and full references. Volume 2 offers 56 high level articles devoted mainly to Formation of Axons and Dendrites, Migration, Synaptogenesis, Developmental Sequences in the Maturation of Intrinsic and Synapse Driven Patterns.

  • Neural Circuit Development and Function in the Healthy and Diseased Brain

    Comprehensive Developmental Neuroscience
    • 1 Edición
    • John Rubenstein + 1 más
    • Inglés
    The genetic, molecular, and cellular mechanisms of neural development are essential for understanding evolution and disorders of neural systems. Recent advances in genetic, molecular, and cell biological methods have generated a massive increase in new information, but there is a paucity of comprehensive and up-to-date syntheses, references, and historical perspectives on this important subject. The Comprehensive Developmental Neuroscience series is designed to fill this gap, offering the most thorough coverage of this field on the market today and addressing all aspects of how the nervous system and its components develop. Particular attention is paid to the effects of abnormal development and on new psychiatric/neurolog... treatments being developed based on our increased understanding of developmental mechanisms. Each volume in the series consists of review style articles that average 15-20pp and feature numerous illustrations and full references. Volume 3 offers 40 high level articles devoted mainly to anatomical and functional development of neural circuits and neural systems, as well as those that address neurodevelopmental disorders in humans and experimental organisms.

  • Patterning and Cell Type Specification in the Developing CNS and PNS

    Comprehensive Developmental Neuroscience
    • 1 Edición
    • John Rubenstein + 1 más
    • Inglés
    The genetic, molecular, and cellular mechanisms of neural development are essential for understanding evolution and disorders of neural systems. Recent advances in genetic, molecular, and cell biological methods have generated a massive increase in new information, but there is a paucity of comprehensive and up-to-date syntheses, references, and historical perspectives on this important subject. The Comprehensive Developmental Neuroscience series is designed to fill this gap, offering the most thorough coverage of this field on the market today and addressing all aspects of how the nervous system and its components develop. Particular attention is paid to the effects of abnormal development and on new psychiatric/neurolog... treatments being developed based on our increased understanding of developmental mechanisms. Each volume in the series consists of review style articles that average 15-20pp and feature numerous illustrations and full references. Volume 1 offers 48 high level articles devoted mainly to patterning and cell type specification in the developing central and peripheral nervous systems.

  • Vertebrate Endocrinology

    • 5 Edición
    • David O. Norris + 1 más
    • Inglés
    Vertebrate Endocrinology represents more than just a treatment of the endocrine system-it integrates hormones with other chemical bioregulatory agents not classically included with the endocrine system. It provides a complete overview of the endocrine system of vertebrates by first emphasizing the mammalian system as the basis of most terminology and understanding of endocrine mechanisms and then applies that to non-mammals. The serious reader will gain both an understanding of the intricate relationships among all of the body systems and their regulation by hormones and other bioregulators, but also a sense of their development through evolutionary time as well as the roles of hormones at different stages of an animal's life cycle.

  • Advances in Applied Microbiology

    • 1 Edición
    • Volumen 83
    • Inglés
    Published since 1959, Advances in Applied Microbiology continues to be one of the most widely read and authoritative review sources in microbiology. The series contains comprehensive reviews of the most current research in applied microbiology. Recent areas covered include bacterial diversity in the human gut, protozoan grazing of freshwater biofilms, metals in yeast fermentation processes and the interpretation of host-pathogen dialogue through microarrays. Eclectic volumes are supplemented by thematic volumes on various topics, including Archaea and sick building syndrome. Impact factor for 2011: 5.233. .

  • Haschek and Rousseaux's Handbook of Toxicologic Pathology

    • 3 Edición
    • Brad Bolon + 4 más
    • Inglés
    Haschek and Rousseaux's Handbook of Toxicologic Pathology is a key reference on the integration of structure and functional changes in tissues associated with the response to pharmaceuticals, chemicals and biologics. The 3e has been expanded by a full volume, and covers aspects of safety assessment not discussed in the 2e. Completely revised with many new chapters, it remains the most authoritative reference on toxicologic pathology for scientists and researchers studying and making decisions on drugs, biologics, medical devices and other chemicals, including agrochemicals and environmental contaminants. New topics include safety assessment, the drug life cycle, risk assessment, communication and management, carcinogenicity assessment, pharmacology and pharmacokinetics, biomarkers in toxicologic pathology, quality assurance, peer review, agrochemicals, nanotechnology, food and toxicologic pathology, the environment and toxicologic pathology and more.

  • Embodiment and Epigenesis: Theoretical and Methodological Issues in Understanding the Role of Biology within the Relational Developmental System

    Part A, Philosophical, Theoretical, and Biological Dimensions
    • 1 Edición
    • Volumen 44
    • Inglés
    Volume 44 of Advances in Child Development and Behavior includes chapters that highlight some the most recent research in the area of embodiment and epigenesis. A wide array of topics are discussed in detail, including cytoplasmic inheritance redux, emergence, self organization and developmental science, and the evolution of intelligent developmental systems. Each chapter provides in-depth discussions, and this volume serves as an invaluable resource for developmental or educational psychology researchers, scholars, and students.

  • Advances in Agronomy

    • 1 Edición
    • Volumen 120
    • Inglés
    Advances in Agronomy continues to be recognized as a leading reference and a first-rate source for the latest research in agronomy. As always, the subjects covered are varied and exemplary of the myriad of subject matter dealt with by this long-running serial

  • Pediatric Demyelinating Disease and its Mimics, An Issue of Neuroimaging Clinics

    • 1 Edición
    • Volumen 23-2
    • Manohar Shroff
    • Inglés
    This issue reviews the state of the art in pediatric demyelinating diseases. Articles cover topics on childhood transverse myelitis, neuromyelitis optica, multiple sclerosis, acute demyelinating encephalopathy, and more.

  • Pediatric Neurology, Part I

    • 1 Edición
    • Volumen 111
    • Olivier Dulac + 2 más
    • Inglés
    The child is neither an adult miniature nor an immature human being: at each age, it expresses specific abilities that optimize adaptation to its environment and development of new acquisitions. Diseases in children cover all specialties encountered in adulthood, and neurology involves a particularly large area, ranging from the brain to the striated muscle, the generation and functioning of which require half the genes of the whole genome and a majority of mitochondrial ones. Human being nervous system is sensitive to prenatal aggression, is particularly immature at birth and development may be affected by a whole range of age-dependent disorders distinct from those that occur in adults. Even diseases more often encountered in adulthood than childhood may have specific expression in the developing nervous system. The course of chronic neurological diseases beginning before adolescence remains distinct from that of adult pathology – not only from the cognitive but also motor perspective, right into adulthood, and a whole area is developing for adult neurologists to care for these children with persisting neurological diseases when they become adults. Just as pediatric neurology evolved as an identified specialty as the volume and complexity of data became too much for the general pediatician or the adult neurologist to master, the discipline has now continued to evolve into so many subspecialties, such as epilepsy, neuromuscular disease, stroke, malformations, neonatal neurology, metabolic diseases, etc., that the general pediatric neurologist no longer can reasonably possess in-depth expertise in all areas, particularly in dealing with complex cases. Subspecialty expertise thus is provided to some trainees through fellowship programmes following a general pediatric neurology residency and many of these fellowships include training in research. Since the infectious context, the genetic background and medical practice vary throughout the world, this diversity needs to be represented in a pediatric neurology textbook. Taken together, and although brain malformations (H. Sarnat & P. Curatolo, 2007) and oncology (W. Grisold & R. Soffietti) are covered in detail in other volumes of the same series and therefore only briefly addressed here, these considerations justify the number of volumes, and the number of authors who contributed from all over the world. Experts in the different subspecialties also contributed to design the general framework and contents of the book. Special emphasis is given to the developmental aspect, and normal development is reminded whenever needed – brain, muscle and the immune system. The course of chronic diseases into adulthood and ethical issues specific to the developing nervous system are also addressed.

  • Pediatric Neurology, Part III

    • 1 Edición
    • Volumen 113
    • Inglés
    The child is neither an adult miniature nor an immature human being: at each age, it expresses specific abilities that optimize adaptation to its environment and development of new acquisitions. Diseases in children cover all specialties encountered in adulthood, and neurology involves a particularly large area, ranging from the brain to the striated muscle, the generation and functioning of which require half the genes of the whole genome and a majority of mitochondrial ones. Human being nervous system is sensitive to prenatal aggression, is particularly immature at birth and development may be affected by a whole range of age-dependent disorders distinct from those that occur in adults. Even diseases more often encountered in adulthood than childhood may have specific expression in the developing nervous system. The course of chronic neurological diseases beginning before adolescence remains distinct from that of adult pathology – not only from the cognitive but also motor perspective, right into adulthood, and a whole area is developing for adult neurologists to care for these children with persisting neurological diseases when they become adults. Just as pediatric neurology evolved as an identified specialty as the volume and complexity of data became too much for the general pediatician or the adult neurologist to master, the discipline has now continued to evolve into so many subspecialties, such as epilepsy, neuromuscular disease, stroke, malformations, neonatal neurology, metabolic diseases, etc., that the general pediatric neurologist no longer can reasonably possess in-depth expertise in all areas, particularly in dealing with complex cases. Subspecialty expertise thus is provided to some trainees through fellowship programmes following a general pediatric neurology residency and many of these fellowships include training in research. Since the infectious context, the genetic background and medical practice vary throughout the world, this diversity needs to be represented in a pediatric neurology textbook. Taken together, and although brain malformations (H. Sarnat & P. Curatolo, 2007) and oncology (W. Grisold & R. Soffietti) are covered in detail in other volumes of the same series and therefore only briefly addressed here, these considerations justify the number of volumes, and the number of authors who contributed from all over the world. Experts in the different subspecialties also contributed to design the general framework and contents of the book. Special emphasis is given to the developmental aspect, and normal development is reminded whenever needed – brain, muscle and the immune system. The course of chronic diseases into adulthood and ethical issues specific to the developing nervous system are also addressed.

  • Pediatric Neurology, Part II

    • 1 Edición
    • Volumen 112
    • Olivier Dulac + 2 más
    • Inglés
    The child is neither an adult miniature nor an immature human being: at each age, it expresses specific abilities that optimize adaptation to its environment and development of new acquisitions. Diseases in children cover all specialties encountered in adulthood, and neurology involves a particularly large area, ranging from the brain to the striated muscle, the generation and functioning of which require half the genes of the whole genome and a majority of mitochondrial ones. Human being nervous system is sensitive to prenatal aggression, is particularly immature at birth and development may be affected by a whole range of age-dependent disorders distinct from those that occur in adults. Even diseases more often encountered in adulthood than childhood may have specific expression in the developing nervous system. The course of chronic neurological diseases beginning before adolescence remains distinct from that of adult pathology – not only from the cognitive but also motor perspective, right into adulthood, and a whole area is developing for adult neurologists to care for these children with persisting neurological diseases when they become adults. Just as pediatric neurology evolved as an identified specialty as the volume and complexity of data became too much for the general pediatician or the adult neurologist to master, the discipline has now continued to evolve into so many subspecialties, such as epilepsy, neuromuscular disease, stroke, malformations, neonatal neurology, metabolic diseases, etc., that the general pediatric neurologist no longer can reasonably possess in-depth expertise in all areas, particularly in dealing with complex cases. Subspecialty expertise thus is provided to some trainees through fellowship programmes following a general pediatric neurology residency and many of these fellowships include training in research. Since the infectious context, the genetic background and medical practice vary throughout the world, this diversity needs to be represented in a pediatric neurology textbook. Taken together, and although brain malformations (H. Sarnat & P. Curatolo, 2007) and oncology (W. Grisold & R. Soffietti) are covered in detail in other volumes of the same series and therefore only briefly addressed here, these considerations justify the number of volumes, and the number of authors who contributed from all over the world. Experts in the different subspecialties also contributed to design the general framework and contents of the book. Special emphasis is given to the developmental aspect, and normal development is reminded whenever needed – brain, muscle and the immune system. The course of chronic diseases into adulthood and ethical issues specific to the developing nervous system are also addressed.

  • Inhaler Devices

    Fundamentals, Design and Drug Delivery
    • 1 Edición
    • Polina Prokopovich
    • Inglés
    Given their direct impact on the health and quality of life for millions, inhalers represent a major turning point in the history of modern medicine. Inhaler devices: Fundamentals, design and drug delivery provides readers with an introduction to the fundamentals of inhaler technology, with a comprehensive discussion of the history of inhalers as well as a discussion on current research and development.Part one discusses the fundamentals and development of inhaler devices as well as drug formulations for inhalers. The treatment of asthma is also discussed. Part two reviews recent developments in drug formulation and nanotechnology for inhaler devices, emerging inhaler technology and possible future trends.Inhaler devices: Fundamentals, design and drug delivery is an essential design guide for good industrial practice, and will be an invaluable resource for those researching and treating conditions such as asthma; and those developing and manufacturing inhalation devices.

  • Emery and Rimoin's Essential Medical Genetics

    • 1 Edición
    • David L. Rimoin + 2 más
    • Inglés
    For decades, Emery and Rimoin’s Principles and Practice of Medical Genetics has provided the ultimate source for practicing clinicians to learn how the study of genetics can be integrated into practice. Developed in parallel to the sixth edition, and featuring 174 original contributions from the many authors of the full set, this one volume work expertly condenses and synthesizes the most clinically relevant content, for convenient desk reference.Helping to bridge the gap between high-level molecular genetics and individual application, it follows the multi-volume set in encompassing scientific fundamentals, full spectrum discussion of major inherited disorders, and actionable therapies. Clinically oriented information is supported by concise descriptions of the principles of genetics, research approaches, and analytics to embrace the evolving population of students, researchers, and practitioners who are integrating their work to provide advanced diagnosis, prevention and treatment of human disease.This print volume is complemented and enhanced with online access to the complete text, online-only references, and high quality illustrations on www.expertconsult.co...

  • The Hip Resurfacing Handbook

    A Practical Guide to the Use and Management of Modern Hip Resurfacings
    • 1 Edición
    • K De Smet + 2 más
    • Inglés
    Hip resurfacing arthroplasty (HRA) using metal-on-metal bearings is an established but specialised technique in joint surgery. Based on the experience of leading experts in the field, The hip resurfacing handbook provides a comprehensive reference for all aspects of this important procedure.The first part of the book reviews and compares all the major hip resurfacing prostheses, their key design features, relevant surgical techniques and clinical results. Part two discusses clinical follow-up of the hip resurfacing patient, including pre- and post-operative examination, acoustic phenomena and rehabilitation. It also covers the use of techniques such as radiography and metal ion measurement, as well as bone scans, ultrasound, CT, MRI, PET and DEXA, to evaluate hip resurfacings. Part three reviews best practice in surgical technique, including the modified posterior and anterior approaches, as well as instrumentation, anaesthesia and revision surgery. Based on extensive retrieval studies, Part four includes examples of the main failure modes in HRA. The final part of the book includes patients’ own experiences, a comparison of HRA with total hip arthroplasty (THA), regulatory issues and relevant web sites.Comprehensive in its scope and authoritative in its coverage, The hip resurfacing handbook is a standard work for orthopaedic surgeons and all those involved in HRA.

  • Genetics and the Behavior of Domestic Animals

    • 2 Edición
    • Temple Grandin + 1 más
    • Inglés
    Behavior is shaped by both genetics and experience--nature and nurture. This book synthesizes research from behavioral genetics and animal and veterinary science, bridging the gap between these fields. The objective is to show that principles of behavioral genetics have practical applications to agricultural and companion animals. The continuing domestication of animals is a complex process whose myriad impacts on animal behavior are commonly under-appreciated. Genetic factors play a significant role in both species-specific behaviors and behavioral differences exhibited by individuals in the same species. Leading authorities explore the impact of increased intensities of selection on domestic animal behavior. Rodents, cattle, pigs, sheep, horses, herding and guard dogs, and poultry are all included in these discussions of genetics and behavior, making this book useful to veterinarians, livestock producers, laboratory animal researchers and technicians, animal trainers and breeders, and any researcher interested in animal behavior.

  • Advances in Immunology

    • 1 Edición
    • Volumen 117
    • Frederick W. Alt
    • Inglés
    Advances in Immunology, a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for the future.

  • Organism and Environment

    • 1 Edición
    • John B. West
    • Inglés

  • An Introduction to Biological Membranes

    From Bilayers to Rafts
    • 1 Edición
    • William Stillwell
    • Inglés
    An Introduction to Biological Membranes: From Bilayers to Rafts covers many aspects of membrane structure/function that bridges membrane biophysics and cell biology. Offering cohesive, foundational information, this publication is valuable for advanced undergraduate students, graduate students and membranologists who seek a broad overview of membrane science.

  • Pharmacy Law and Practice

    • 5 Edición
    • Jon Merrills + 1 más
    • Inglés
    Pharmacy Law and Practice, Fifth Edition provides a straightforward and useable guide for students, practitioners, academics and others interested in pharmacy law and practice in the United Kingdom. This multi-dimensional book includes discussions of socio-political influences on legal developments to provide greater insight to the reader. It clearly sets out the background to regulatory issues together with simple and practical statements of what a pharmacist has to do to obey the law. As in previous editions, this book discusses topics thematically rather than by statute. It is a unique and reader-friendly guide that boils down the complex or difficult language of the law, describes the reasons behind it, and illustrates the application to pharmacy practice.

  • Drug-Induced Liver Disease

    • 3 Edición
    • Neil Kaplowitz + 1 más
    • Inglés
    This field has shown tremendous growth in recent years, primarily due to the recognition that drug-induced liver disease is the most common cause of liver failure and one of the major contributors to the withdrawal of drugs developed by the pharmaceutical industry. Drug-Induced Liver Disease, 3rd edition is a comprehensive reference that covers mechanisms of injury, diagnosis and management, major hepatotoxins, regulatory perspectives and much more. Written by highly respected authorities, this new edition is an updated and definitive reference for clinicians and scientists in academia, the pharmaceutical industry and government settings. This book contains 4 new chapters on key topics in the area and provides a current and extensive review of the latest developments concerning the toxicology, pharmacology, genetics and immunology of drug-induced liver disease.

  • Anorexia

    • 1 Edición
    • Volumen 92
    • Inglés
    First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. The Editorial Board now reflects expertise in the field of hormone action, vitamin action, X-ray crystal structure, physiology and enzyme mechanisms. Under the capable and qualified editorial leadership of Dr. Gerald Litwack, Vitamins and Hormones continues to publish cutting-edge reviews of interest to endocrinologists, biochemists, nutritionists, pharmacologists, cell biologists and molecular biologists. Others interested in the structure and function of biologically active molecules like hormones and vitamins will, as always, turn to this series for comprehensive reviews by leading contributors to this and related disciplines. This volume focuses on anorexia.

  • Fenichel's Clinical Pediatric Neurology

    A Signs and Symptoms Approach (Expert Consult - Online and Print)
    • 7 Edición
    • J. Eric Piña-Garza
    • Inglés
    Confidently diagnose and manage primary neurologic disorders of childhood with actionable, step-by-step assistance from Fenichel’s Clinical Pediatric Neurology! A signs-and-symptoms-b... approach - with consideration of each presenting symptom in terms of differential diagnosis and treatment - mirrors the way you would typically evaluate and manage a patient. A practical and well-organized introduction to pediatric neurology, this is an ideal resource for board exam preparation, office use, and reference during residency.

  • Epigenetics and Development

    • 1 Edición
    • Volumen 104
    • Inglés
    This new volume of Current Topics in Developmental Biology covers epigenetics and development, with contributions from an international board of authors. The chapters provide a comprehensive set of reviews covering such topics as epigenetic marking of the zebrafish developmental program, functions of DNA methylation and hydroxymethylation in mammalian development, and reprogramming and the pluripotent stem cell cycle.

  • Practical Pediatric Endocrinology in a Limited Resource Setting

    • 1 Edición
    • Margaret Zacharin
    • Inglés
    Practical Pediatric Endocrinology in a Limited Resource Setting provides a guide for managing pediatric endocrine problems in a limited resource setting, together with an outline of the bases for these disorders. The book outlines a plan for coming to a likely diagnosis in situations where resources are constrained, and suggests ways to access more sophisticated technologies for diagnostic confirmation and extension of available tools. Further extending and complementing each chapter is a series of scenarios for use as teaching and learning tools. Together with a clinical question, all chapters include a suggested outline for assessment that assists readers facing similar situations in daily practice. Each scenario works through a typical series of deductive steps used to establish a working diagnosis, while considering both a differential diagnosis and reminding readers of current knowledge around the subject matter.

  • Computer-Aided Applications in Pharmaceutical Technology

    • 1 Edición
    • Jelena Duris
    • Inglés
    Research and development in the pharmaceutical industry is a time-consuming and expensive process, making it difficult for newly developed drugs to be formulated into commercially available products. Both formulation and process development can be optimized by means of statistically organized experiments, artificial intelligence and other computational methods. Simultaneous development and investigation of pharmaceutical products and processes enables application of quality by design concept that is being promoted by the regulatory authorities worldwide. Computer-Aided Applications in Pharmaceutical Technology covers the fundamentals of experimental design application and interpretation in pharmaceutical technology, chemometric methods with emphasis of their application in process control, neural computing (artificial neural networks, fuzzy logic and decision trees, evolutionary computing and genetic algorithms, self-organizing maps), computer-aided biopharmaceutical characterization as well as application of computational fluid dynamics in pharmaceutical technology. All of these techniques are essential tools for successful building of quality into pharmaceutical products and processes from the early stage of their development to selection of the optimal ones. In addition to theoretical aspects of various methods, the book provides numerous examples of their application in the field of pharmaceutical technology.

  • Cereal Grains for the Food and Beverage Industries

    • 1 Edición
    • Elke K Arendt + 1 más
    • Inglés
    Cereals are a staple of the human diet and have a significant effect on health. As a result, they are of major significance to the food industry. Cereal grains for the food and beverage industries provides a comprehensive overview of all of the important cereal and pseudo-cereal species, from their composition to their use in food products.The book reviews the major cereal species, starting with wheat and triticale before covering rye, barley and oats. It goes on to discuss other major species such as rice, maize, sorghum and millet, as well as pseudo-cereals such as buckwheat, quinoa and amaranth. Each chapter reviews grain structure, chemical composition (including carbohydrate and protein content), processing and applications in food and beverage products.Cereal grains for the food and beverage industries is an essential reference for academic researchers interested in the area of cereal grains and products. It is also an invaluable reference for professionals in the food and beverage industry working with cereal products, including ingredient manufacturers, food technologists, nutritionists, as well as policy-makers and health care professionals.

  • Deterministic Versus Stochastic Modelling in Biochemistry and Systems Biology

    • 1 Edición
    • Paola Lecca + 2 más
    • Inglés
    Stochastic kinetic methods are currently considered to be the most realistic and elegant means of representing and simulating the dynamics of biochemical and biological networks. Deterministic versus stochastic modelling in biochemistry and systems biology introduces and critically reviews the deterministic and stochastic foundations of biochemical kinetics, covering applied stochastic process theory for application in the field of modelling and simulation of biological processes at the molecular scale. Following an overview of deterministic chemical kinetics and the stochastic approach to biochemical kinetics, the book goes onto discuss the specifics of stochastic simulation algorithms, modelling in systems biology and the structure of biochemical models. Later chapters cover reaction-diffusion systems, and provide an analysis of the Kinfer and BlenX software systems. The final chapter looks at simulation of ecodynamics and food web dynamics.

  • Insect Molecular Genetics

    An Introduction to Principles and Applications
    • 3 Edición
    • Marjorie A. Hoy
    • Inglés
    Insect Molecular Genetics, Third Edition, summarizes and synthesizes two rather disparate disciplines—entomolo... and molecular genetics. This volume provides an introduction to the techniques and literature of molecular genetics; defines terminology; and reviews concepts, principles, and applications of these powerful tools. The world of insect molecular genetics, once dominated by Drosophila, has become much more diverse, especially with the sequencing of multiple arthropod genomes (from spider mites to mosquitoes). This introduction includes discussion of honey bees, mosquitoes, flour beetles, silk moths, fruit flies, aphids, house flies, kissing bugs, cicadas, butterflies, tsetse flies and armyworms. This book serves as both a foundational text and a review of a rapidly growing literature. With fully revised and updated chapters, the third edition will be a valuable addition to the personal libraries of entomologists, geneticists, and molecular biologists.

  • Organisation of Chromosomes

    • 1 Edición
    • Volumen 90
    • Inglés
    Published continuously since 1944, the Advances in Protein Chemistry and Structural Biology serial has been a continuous, essential resource for protein chemists. Covering reviews of methodology and research in all aspects of protein chemistry, including purification/express... proteomics, modeling and structural determination and design, each volume brings forth new information about protocols and analysis of proteins while presenting the most recent findings from leading experts in a broad range of protein-related topics.

  • Lipid Oxidation

    Challenges in Food Systems
    • 1 Edición
    • Amy S. Logan + 2 más
    • Inglés
    Lipid oxidation in food systems is one of the most important factors which affect food quality, nutrition, safety, color and consumers’ acceptance. The control of lipid oxidation remains an ongoing challenge as most foods constitute very complex matrices. Lipids are mostly incorporated as emulsions, and chemical reactions occur at various interfaces throughout the food matrix. Recently, incorporation of healthy lipids into food systems to deliver the desired nutrients is becoming more popular in the food industry. Many food ingredients contain a vast array of components, many of them unknown or constituting diverse or undefined molecular structures making the need in the food industry to develop effective approaches to mitigate lipid oxidation in food systems. This book provides recent perspectives aimed at a better understanding of lipid oxidation mechanisms and strategies to improve the oxidative stability of food systems.

  • Building the Most Complex Structure on Earth

    An Epigenetic Narrative of Development and Evolution of Animals
    • 1 Edición
    • Nelson R Cabej
    • Inglés
    Building the Most Complex Structure on Earth provides readers with a basic biological education an easy and understandable introduction into a new epigenetic theory of development and evolution. This is a novel theory that describes the epigenetic mechanisms of the development and evolution of animals and explains the colossal evolution and diversification of animals from a new post-genetic perspective. Modern biology has demonstrated the existence of a common genetic toolkit in the animal kingdom, but neither the number of genes nor the evolution of new genes is responsible for the development and evolution of animals. The failure to understand how the same genetic toolkit is used to produce millions of widely different animal forms remains a perplexing conundrum in modern biology. The novel theory shows that the development and evolution of the animal kingdom are functions of epigenetic mechanisms, which are the competent users of the genetic toolkit.

  • Advances in Parasitology

    • 1 Edición
    • Volumen 82
    • Inglés
    First published in 1963, Advances in Parasitology contains comprehensive and up-to-date reviews in all areas of interest in contemporary parasitology. Advances in Parasitology includes medical studies on parasites of major influence, such as Plasmodium falciparum and trypanosomes. The series also contains reviews of more traditional areas, such as zoology, taxonomy, and life history, which shape current thinking and applications. Eclectic volumes are supplemented by thematic volumes on various topics, including control of human parasitic diseases and global mapping of infectious diseases.

  • Rabies

    Scientific Basis of the Disease and Its Management
    • 3 Edición
    • Alan C. Jackson
    • Inglés
    Rabies remains one of the most important global public health problems worldwide. Although many important developments have been made over the past century to combat this ancient disease, Rabies has become a re-emergent infection in the developing world. The 3e updates this classic reference with comprehensive coverage of the molecular virology, pathogenesis, vaccines, public health, immunology, and epidemiology of Rabies. Chapters new to this edition cover biothreat/bioterrori... successful wildlife control and therapies of human Rabies, and the emergence of new lyssavirus species Rabies provides physicians, public health advisors, epidemiologists, research scientists and veterinarians with single source, authoritative and up-to-date information on the diagnosis, treatment, control and prevention of this fatal infectious virus that continues to kill over 70,000 people a year.

  • Bacterial Cellular Metabolic Systems

    Metabolic Regulation of a Cell System with 13C-Metabolic Flux Analysis
    • 1 Edición
    • K. Shimizu
    • Inglés
    The metabolic regulation of a cell system is of critical importance in systems biology, and a robust model of these mechanisms is essential in predicting the effects on the metabolism of both the culture environment and the knockout of specific genes. Bacterial cellular metabolic systems focuses on this highly topical subject in relation to culture environment and provides a detailed analysis from gene level to metabolic level regulation, as well as offering a discussion of the most recent modelling approaches. The book begins with an introduction to metabolic mechanisms and to the metabolic regulation of a cell, before moving on to discussing the action of global regulators in response to a specific culture environment. The second half of the book examines conventional flux balance analysis and its applications, 13C-metabolic flux analysis, and the effect of a specific gene knockout on the metabolism.

  • Fibre-Rich and Wholegrain Foods

    Improving Quality
    • 1 Edición
    • Jan A Delcour + 1 más
    • Inglés
    Consumers are increasingly seeking foods that are rich in dietary fibre and wholegrains, but are often unwilling to compromise on sensory quality. Fibre-rich and wholegrain food reviews key research and best industry practice in the development of fibre-enriched and wholegrain products that efficiently meet customer requirements.Part one introduces the key issues surrounding the analysis, definition, regulation and health claims associated with dietary fibre and wholegrain foods. The links between wholegrain foods and health, the range of fibre dietary ingredients and a comparison of their technical functionality are discussed, as are consumption and consumer challenges of wholegrain foods. Part two goes on to explore dietary fibre sources, including wheat and non-wheat cereal dietary fibre ingredients, vegetable, fruit and potato fibres. Improving the quality of fibre-rich and wholegrain foods, including such cereal products as wholegrain bread, muffins, pasta and noodles, is the focus of part three. Fibre in extruded products is also investigated before part four reviews quality improvement of fibre-enriched dairy products, meat products, seafood, beverages and snack foods. Companion animal nutrition as affected by dietary fibre inclusion is discussed, before the book concludes with a consideration of soluble and insoluble fibre in infant nutrition.With its distinguished editors and international team of expert contributors, Fibre-rich and wholegrain foods provides a comprehensive guide to the field for researchers working in both the food industry and academia, as well as all those involved in the development, production and use of fibre-enriched and wholegrain foods.

  • Herpetology

    An Introductory Biology of Amphibians and Reptiles
    • 4 Edición
    • Laurie J. Vitt + 1 más
    • Inglés
    The fourth edition of the textbook Herpetology covers the basic biology of amphibians and reptiles, with updates in nearly every conceptual area. Not only does it serve as a solid foundation for modern herpetology courses, but it is also relevant to courses in ecology, behavior, evolution, systematics, and morphology. Examples taken from amphibians and reptiles throughout the world make this book a useful herpetology textbook in several countries. Naturalists, amateur herpetologists, herpetoculturists, zoo professionals, and many others will find this book readable and full of relevant natural history and distributional information. Amphibians and reptiles have assumed a central role in research because of the diversity of ecological, physiological, morphological, behavioral, and evolutionary patterns they exhibit. This fully revised edition brings the latest research to the reader, ranging over topics in evolution, reproduction, behavior and more, allowing students and professionals to keep current with a quickly moving field.

  • Atlas of Drosophila Morphology

    Wild-type and Classical Mutants
    • 1 Edición
    • Sylwester Chyb + 1 más
    • Inglés
    The Atlas of Drosophila Morphology: Wild-type and Classical Mutants is the guide every Drosophila researcher wished they had when first learning genetic markers, and the tool they wish they had now as a handy reference in their lab research. Previously, scientists had only poor-quality images or sketches to work with, and then scattered resources online - but no single visual resource quickly at their fingertips when explaining markers to new members of the lab, or selecting flies to do their genetic crosses, or hybrids. This alphabetized guide to Drosophila genetic markers lays flat in the lab for easy referencing. It contains high-resolution images of flies and the appropriate marker on the left side of each page and helpful information for the marker on the facing page, such as symbol, gene name, synonyms, chromosome location, brief informative description of the morphology, and comments on marker reliability. A companion website with updated information, useful links, and additional data provided by the authors complements this extremely valuable resource.

  • Synthetic Biology

    Tools and Applications
    • 1 Edición
    • Huimin Zhao
    • Inglés
    Synthetic Biology provides a framework to examine key enabling components in the emerging area of synthetic biology. Chapters contributed by leaders in the field address tools and methodologies developed for engineering biological systems at many levels, including molecular, pathway, network, whole cell, and multi-cell levels. The book highlights exciting practical applications of synthetic biology such as microbial production of biofuels and drugs, artificial cells, synthetic viruses, and artificial photosynthesis. The roles of computers and computational design are discussed, as well as future prospects in the field, including cell-free synthetic biology and engineering synthetic ecosystems.Synthetic biology is the design and construction of new biological entities, such as enzymes, genetic circuits, and cells, or the redesign of existing biological systems. It builds on the advances in molecular, cell, and systems biology and seeks to transform biology in the same way that synthesis transformed chemistry and integrated circuit design transformed computing. The element that distinguishes synthetic biology from traditional molecular and cellular biology is the focus on the design and construction of core components that can be modeled, understood, and tuned to meet specific performance criteria and the assembly of these smaller parts and devices into larger integrated systems that solve specific biotechnology problems.

  • Advances in Food and Nutrition Research

    • 1 Edición
    • Volumen 69
    • Inglés
    Advances in Food and Nutrition Research recognizes the integral relationship between the food and nutritional sciences and brings together outstanding and comprehensive reviews that highlight this relationship. Contributions detail scientific developments in the broad areas of food science and nutrition and are intended to provide those in academia and industry with the latest information on emerging research in these constantly evolving sciences.

  • Microbial Production of Food Ingredients, Enzymes and Nutraceuticals

    • 1 Edición
    • Brian McNeil + 3 más
    • Inglés
    Bacteria, yeast, fungi and microalgae can act as producers (or catalysts for the production) of food ingredients, enzymes and nutraceuticals. With the current trend towards the use of natural ingredients in foods, there is renewed interest in microbial flavours and colours, food bioprocessing using enzymes and food biopreservation using bacteriocins. Microbial production of substances such as organic acids and hydrocolloids also remains an important and fast-changing area of research. Microbial production of food ingredients, enzymes and nutraceuticals provides a comprehensive overview of microbial production of food ingredients, enzymes and nutraceuticals.Part one reviews developments in the metabolic engineering of industrial microorganisms and advances in fermentation technology in the production of fungi, yeasts, enzymes and nutraceuticals. Part two discusses the production and application in food processing of substances such as carotenoids, flavonoids and terponoids, enzymes, probiotics and prebiotics, bacteriocins, microbial polysaccharides, polyols and polyunsaturated fatty acids.Microbial production of food ingredients, enzymes and nutraceuticals is an invaluable guide for professionals in the fermentation industry as well as researchers and practitioners in the areas of biotechnology, microbiology, chemical engineering and food processing.

  • Back to Basics in Physiology

    Fluids in the Renal and Cardiovascular Systems
    • 1 Edición
    • Juan Pablo Arroyo + 1 más
    • Inglés
    This original six chapter book will briefly review and integrate the basic concepts behind water distribution and movement in the body. This fills a knowledge gap that most medical and undergraduate physiology students acquire when these topics are studied separately. As of now, there is no textbook that fully integrates renal, cardiovascular and water physiology in a clear understandable manner. The book is intended primarily for medical students and undergraduate physiology students. Chapters include: 1) Water and its Distribution; 2) Water Dynamics; 3) Fluid Handling by the Heart and Blood Vessels; 4) Fluid Handling by the Kidneys; 5) Water and Oxygen Delivery; 6) Integration in the Response to Hemorrhage, Volume Depletion, and Water Redistribution.

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