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Elsevier

Libros en Ciencias de la Vida

  • Context Effects on Embodied Representation of Language Concepts

    • 1 Edición
    • Jie Yang
    • Inglés
    Embodied theories claim that semantic representations are grounded in sensorimotor systems, but the contribution of sensorimotor brain areas in representing meaning is still controversial. One current debate is whether activity in sensorimotor areas during language comprehension is automatic. Numerous neuroimaging studies reveal activity in perception and action areas during semantic processing that is automatic and independent of context, but increasing findings show that involvement of sensorimotor areas and the connectivity between word-form areas and sensorimotor areas can be modulated by contextual information. Context Effects on Embodied Representation of Language Concepts focuses on these findings and discusses the influences from word, phrase, and sentential contexts that emphasize either dominant conceptual features or non-dominant conceptual features.

  • Emery and Rimoin's Principles and Practice of Medical Genetics

    • 6 Edición
    • David L. Rimoin + 2 más
    • Inglés
    For decades, Emery and Rimoin’s Principles and Practice of Medical Genetics has provided the ultimate source for practicing clinicians to learn how the study of genetics can be integrated into practice. With almost 5,000 pages of detailed coverage, this fully online sixth edition of the classic reference adds the latest information on prenatal diagnosis, genetic screening, genetic counseling, and treatment strategies to complete its coverage of the growing field for medical students, residents and physicians involved in the care of patients with genetic conditions. Clinically oriented information is supported by expanded sections on basic principles of genetics, research approaches, and analytics to embrace the evolving population of students, researchers, and practitioners who are integrating their work to provide advanced diagnosis, prevention and treatment of human disease. With advances in high-throughput technologies propelling the closer integration of lab and clinical work, this edition bridges the gap between high-level molecular genetics and clinical application.

  • Diamond-Based Materials for Biomedical Applications

    • 1 Edición
    • Roger Narayan
    • Inglés
    Carbon is light-weight, strong, conductive and able to mimic natural materials within the body, making it ideal for many uses within biomedicine. Consequently a great deal of research and funding is being put into this interesting material with a view to increasing the variety of medical applications for which it is suitable. Diamond-based materials for biomedical applications presents readers with the fundamental principles and novel applications of this versatile material.Part one provides a clear introduction to diamond based materials for medical applications. Functionalization of diamond particles and surfaces is discussed, followed by biotribology and biological behaviour of nanocrystalline diamond coatings, and blood compatibility of diamond-like carbon coatings. Part two then goes on to review biomedical applications of diamond based materials, beginning with nanostructured diamond coatings for orthopaedic applications. Topics explored include ultrananocrystalline diamond for neural and ophthalmological applications, nanodiamonds for drug delivery systems, and diamond nucleation and seeding techniques for tissue regeneration. Finally, the book concludes with a discussion of diamond materials for microfluidic devices.With its distinguished editors and international team of expert contributors, Diamond-based materials for biomedical applications is an authoritative guide for all materials scientists, researchers, medical practitioners and academics investigating the properties and uses of diamond based materials in the biomedical environment.

  • Engineered Nanopores for Bioanalytical Applications

    • 1 Edición
    • Joshua B. Edel + 1 más
    • Inglés
    Engineered Nanopores for Bioanalytical Applications is the first book to focus primarily on practical analytical applications of nanopore development. These nanoscale analytical techniques have exciting potential because they can be used in applications such as DNA sequencing, DNA fragment sizing, DNA/protein binding, and protein/protein binding.This book provides a solid professional reference on nanopores for readers in academia, industry and engineering and biomedical fields. In addition, the book describes the instrumentation, fabrication, and experimental methods necessary to carry out nanopore-based experiments for developing new devices.

  • Biofabrication

    Micro- and Nano-fabrication, Printing, Patterning and Assemblies
    • 1 Edición
    • Gabor Forgacs + 1 más
    • Inglés
    Biofabrication is a practical guide to the novel, inherently cross-disciplinary scientific field that focuses on biomanufacturing processes and a related range of emerging technologies. These processes and technologies ultimately further the development of products that may involve living (cells and/or tissues) and nonliving (bio-supportive proteins, scaffolds) components. The book introduces readers to cell printing, patterning, assembling, 3D scaffold fabrication, cell/tissue-on-chips as a coherent micro-/nano-fabricat... toolkit. Real-world examples illustrate how to apply biofabrication techniques in areas such as regenerative medicine, pharmaceuticals and tissue engineering. In addition to being a vital reference for scientists, engineers and technicians seeking to apply biofabrication techniques, this book also provides an insight into future developments in the field, and potential new applications.

  • Memory Reconsolidation

    • 1 Edición
    • Cristina M. Alberini
    • Inglés
    As little as 10 years ago, it was believed that memory went from short to long term via one consolidation practice that made that memory intractable. Since then, research has shown that long-term memories can be activated, modified, and reconsolidated in their new form. This research indicates that memories are more dynamic than once believed. And understanding how this process works and helping people to redefine established memories can be clinically useful if those memories lead to problems, as is the case in post-traumatic stress disorder. This book provides a comprehensive overview of research on memory reconsolidation; what this has to say about the formation, storage, and changeability of memory; and the potential applications of this research to treating clinical disorders.

  • Forest Monitoring

    Methods for terrestrial investigations in Europe with an overview of North America and Asia
    • 1 Edición
    • Volumen 12
    • Inglés
    The demand for comparable, long-term, high quality data on forest ecosystems' status and changes is increasing at the international and global level. Yet, sources for such data are limited and in many case it is not possible to compare data from different monitoring initiatives across space and time because of methodological differences. Apart from technical manuals, there is no comprehensive multidisciplinary, scientific, peer-reviewed reference for forest monitoring methods that can serve and support the user community. This book provides in a single reference the state-of-the-art of monitoring methods as applied at the international level.The book present scientific concepts and methods that form the basis of the transnational, long-term forest monitoring in Europe and looks at other initiatives at the global level. Standardized methods that have been developed over two decades in international forest monitoring projects are presented. Emphasis is put on trans-nationally harmonized methods, related data quality issues, current achievements and on remaining open questions.

  • Cilia, Part B

    • 1 Edición
    • Volumen 525
    • Inglés
    This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers cilia and includes chapters on such topics as methods for studying ciliary polarity in Xenopus, analysis of signaling pathways in mammalian spermatozoa, and biochemical and physiological analysis of axonemal dyneins.

  • Mycoviruses

    • 1 Edición
    • Volumen 86
    • Inglés
    This volume of Advances in Virus Research focuses on mycoviruses. The authors and reviews represent the most current and cutting-edge research in the field. A broad range of research is presented from research experts.

  • Advances in Clinical Chemistry

    • 1 Edición
    • Volumen 60
    • Inglés
    Written by authors representing the diverse field of clinical chemistry and diagnostics, reviews in Advances in Clinical Chemistry cover a range of cutting-eduge research ranging from basic biochemical exploration to microarray technology.

  • Cilia, Part A

    • 1 Edición
    • Volumen 524
    • Inglés
    This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers cilia and includes chapters on such topics as electron microscopy of IFT in cilia and flagella, radial spoke isolation and assays, and biomechanical measurements of kinocilium.

  • Genome Evolution of Photosynthetic Bacteria

    • 1 Edición
    • Volumen 66
    • Inglés
    Advances in Botanical Research publishes in-depth and up-to-date reviews on a wide range of topics in plant sciences. The series features a wide range of reviews by recognized experts on all aspects of plant genetics, biochemistry, cell biology, molecular biology, physiology and ecology. This thematic volume features reviews on genome evolution of photosynthetic bacteria.

  • The Molecular Biology of Cadherins

    • 1 Edición
    • Volumen 116
    • Inglés
    This volume of Progress in Molecular Biology and Translational Science focuses on the most recent research surrounding Cadherins from top experts in the field.

  • Primate Adaptation and Evolution

    • 3 Edición
    • John G. Fleagle
    • Inglés
    Primate Adaptation and Evolution, Third Edition, is a thorough revision of the text of choice for courses in primate evolution. The book retains its grounding in the extant primate groups as the best way to understand the fossil trail and the evolution of these modern forms. However, this coverage is now streamlined, making reference to the many new and excellent books on living primate ecology and adaptation – a field that has burgeoned since the first edition of Primate Adaptation and Evolution. By drawing out the key features of the extant families and referring to more detailed texts, the author sets the scene and also creates space for a thorough updating of the exciting developments in primate palaeontology – and the reconstruction through early hominid species – of our own human origins. This updated version covers recent developments in primate paleontology and the latest taxonomy, and includes over 200 new illustrations and revised evolutionary trees. This text is ideal for undergraduate and post-graduate students studying the evolution and functional ecology of primates and early fossil hominids.

  • Advances in Microbial Physiology

    • 1 Edición
    • Volumen 62
    • Inglés
    Advances in Microbial Physiology is one of the most successful and prestigious series from Academic Press, an imprint of Elsevier. It publishes topical and important reviews, interpreting physiology to include all material that contributes to our understanding of how microorganisms and their component parts work. First published in 1967, it is now in its 62nd volume. The Editors have always striven to interpret microbial physiology in the broadest context and have never restricted the contents to “traditional” views of whole cell physiology. Now edited by Professor Robert Poole, University of Sheffield, Advances in Microbial Physiology continues to be an influential and very well reviewed series.

  • Foodborne Infections and Intoxications

    • 4 Edición
    • J. Glenn Morris Jr.
    • Inglés
    The accelerated globalization of the food supply, coupled with toughening government standards, is putting global food production, distribution, and retail industries under a high-intensity spotlight. High-publicity cases about foodborne illnesses over recent years have heightened public awareness of food safety issues, and momentum has been building to find new ways to detect and identify foodborne pathogens and eliminate food-related infections and intoxications. This extensively revised 4e covers how the incidence and impact of foodborne diseases is determined, foodborne intoxications with an introduction noting common features among these diseases and control measures that are applicable before and after the basic foodstuff is harvested.

  • Advances in Applied Microbiology

    • 1 Edición
    • Volumen 82
    • Inglés
    Published since 1959, Advances in Applied Microbiology continues to be one of the most widely read and authoritative review sources in microbiology. The series contains comprehensive reviews of the most current research in applied microbiology. Recent areas covered include bacterial diversity in the human gut, protozoan grazing of freshwater biofilms, metals in yeast fermentation processes and the interpretation of host-pathogen dialogue through microarrays. Eclectic volumes are supplemented by thematic volumes on various topics, including Archaea and sick building syndrome. Impact factor for 2011: 5.233. .

  • Culinary Nutrition

    The Science and Practice of Healthy Cooking
    • 1 Edición
    • Jacqueline B. Marcus
    • Inglés
    Culinary Nutrition: The Science and Practice of Healthy Cooking is the first textbook specifically written to bridge the relationship between food science, nutrition and culinology as well as consumer choices for diet, health and enjoyment. The book uses a comprehensive format with real-life applications, recipes and color photographs of finished dishes to emphasize the necessity of sustainably deliverable, health-beneficial and taste-desirable products. With pedagogical elements to enhance and reinforce learning opportunities, this book explores what foods involve the optimum nutritional value for dietary needs, including specific dietary requirements and how foods are produced. It also considers alternative production methods, along with the impact of preparation on both the nutritional value of a food and its consumer acceptability. Other discussions focus on the basics of proteins, carbohydrates, and lipids, issues of diet and disease such as weight management, and food production and preparation. Laboratory-type, in-class activities are presented using limited materials and applications of complex concepts in real-life situations. This book will be a valuable resource for undergraduate students in culinary nutrition, nutrition science, food science and nutrition, and culinary arts courses. It will also appeal to professional chefs and food scientists as well as research chefs in product development.

  • Brenner's Encyclopedia of Genetics

    • 2 Edición
    • Stanley Maloy + 1 más
    • Inglés
    The explosion of the field of genetics over the last decade, with the new technologies that have stimulated research, suggests that a new sort of reference work is needed to keep pace with such a fast-moving and interdisciplinary field. Brenner's Encyclopedia of Genetics, Second Edition, Seven Volume Set, builds on the foundation of the first edition by addressing many of the key subfields of genetics that were just in their infancy when the first edition was published. The currency and accessibility of this foundational content will be unrivalled, making this work useful for scientists and non-scientists alike.Featuring relatively short entries on genetics topics written by experts in that topic, Brenner's Encyclopedia of Genetics, Second Edition, Seven Volume Set provides an effective way to quickly learn about any aspect of genetics, from Abortive Transduction to Zygotes. Adding to its utility, the work provides short entries that briefly define key terms, and a guide to additional reading and relevant websites for further study. Many of the entries include figures to explain difficult concepts. Key terms in related areas such as biochemistry, cell, and molecular biology are also included, and there are entries that describe historical figures in genetics, providing insights into their careers and discoveries.

  • Corridors to Extinction and the Australian Megafauna

    • 1 Edición
    • Steve Webb
    • Inglés
    Extinctions have always occurred and always will, so what is so surprising about the megafauna extinctions? They were caused by humans and were the first of many extinctions that eventually led to the extinction of the Moa, Steller's Sea Cow, the Dodo, Great Auk and countless other species great and small, all attributed to human agency. Therefore, the megafauna were humans’ first great impact on the planet. There is now an increasing realization that the 'blitzkrieg' view of these extinctions may have been wrong. A growing body of evidence and long-term field work is beginning to show that at least Australia's megafauna did not succumb to human agency, not because humans probably did not hunt the odd animal but because the an infinitely more logical reason lies in the climatic conditions of the Quaternary Ice Ages and the affect they had on continental geography, environment, climate and, most importantly, the biogeography of the megafauna. This book presents the evidence of this theory, demonstrating the biogeographic approach to Australia’s megafauna extinction.

  • Trends in Packaging of Food, Beverages and Other Fast-Moving Consumer Goods (FMCG)

    Markets, Materials and Technologies
    • 1 Edición
    • Neil Farmer
    • Inglés
    Packaging plays an essential role in protecting and extending the shelf life of a wide range of foods, beverages and other fast-moving consumer goods. There have been many key developments in packaging materials and technologies in recent years, and Trends in packaging of food, beverages and other fast-moving consumer goods (FMCG) provides a concise review of these developments and international market trends.Beginning with a concise introduction to the present status and trends in innovations in packaging for food, beverages and other fast-moving consumer goods, the book goes on to consider modified atmosphere packaging and other active packaging systems, including smart and intelligent packaging, and the role these play in augmenting and securing the consumer brand experience. Developments in plastic and bioplastic materials and recycling systems are then discussed, followed by innovations and trends in metal, paper and paperboard packaging. Further chapters review international environmental and sustainability regulatory and legislative frameworks, before the use of nanotechnology, smart and interactive packaging developments for enhanced communication at the packaging/user interface are explored. Finally, the book concludes by considering potential future trends in materials and technologies across the international packaging market.With its distinguished editor and international team of expert contributors, Trends in packaging of food, beverages and other fast-moving consumer goods (FMCG) is an important reference tool, providing a practical overview of emerging packaging technologies and market trends for research and design professionals in the food and packaging industry, and academics working in this area.

  • International Review of Cell and Molecular Biology

    • 1 Edición
    • Volumen 303
    • Kwang W. Jeon
    • Inglés
    International Review of Cell and Molecular Biology presents current advances and comprehensive reviews in cell biology--both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth.

  • Mesenchymal Stem Cells and Skeletal Regeneration

    • 1 Edición
    • Peter Giannoudis + 3 más
    • Inglés
    Mesenchymal Stem Cells and Skeletal Regeneration covers our current understanding of the role of mesenchymal stem cells (MSCs) and other mesenchymal progenitors in skeletal regeneration, encompassing bone, cartilage and whole joint regeneration. The expansion reflects developments in the field to include data on the use of MSCs in drug development, growth factors, scaffolds and biomechanical manipulations for skeletal trauma and diseases, including osteoporosis and arthritis. Written for an audience of clinicians and young researchers who are exposed to MSCs in their work, this work summarizes recent findings pertaining to the definition and characterization of MSCs in skeletal tissues and discusses the mechanisms of their actions in regeneration of bone in vivo. The authors describe recent findings pertaining to the efficacy of MSC therapies in animal models and in human clinical trials and bring together literature showing that the ways MSCs are extracted, expanded and implanted can considerably affect bone formation outcomes. Finally, it presents the latest knowledge on the nature of native MSCs in skeletal tissues, which provide a platform for novel in situ tissue regeneration approaches for systemic bone disease such as osteoporosis.

  • The Agronomy and Economy of Turmeric and Ginger

    The Invaluable Medicinal Spice Crops
    • 1 Edición
    • K.P. Prabhakaran Nair
    • Inglés
    Turmeric has been used as a medicine, a condiment, and a dye since at least 600 B.C., while ginger has been used extensively throughout history for its medicinal purposes. The Agronomy and Economy of Turmeric and Ginger brings these two important plants together in one reference book, explaining their history, production techniques, and nutritional and medicinal properties in detail. This book is intuitively organized by plant and use, allowing quick access to information. It puts the uniquely Indian use and history of turmeric and ginger plants into a global context of production and economic aspects. It explores the plants from a botanical perspective, and goes into details of their chemical composition as well. Rounding out the book are chapters on disease and pest control issues. The book is a valuable resource for those involved in the production and marketing of these plants, as well as those looking for more information on the medicinal and nutritional properties of turmeric and ginger.

  • Advances in Aquaculture Hatchery Technology

    • 1 Edición
    • Geoff Allan + 1 más
    • Inglés
    Aquaculture is the fastest-growing food production sector in the world. With demand for seafood increasing at astonishing rates, the optimization of production methods is vital. One of the primary restrictions to continued growth is the supply of juveniles from hatcheries. Addressing these constraints, Advances in aquaculture hatchery technology provides a comprehensive, systematic guide to the use of current and emerging technologies in enhancing hatchery production.Part one reviews reproduction and larval rearing. Aquaculture hatchery water supply and treatment systems, principles of finfish broodstock management, genome preservation, and varied aspects of nutrition and feeding are discussed in addition to larval health management and microbial management for bacterial pathogen control. Closing the life-cycle and overcoming challenges in hatchery production for selected invertebrate species are the focus of part two, and advances in hatchery technology for spiny lobsters, shrimp, blue mussel, sea cucumbers and cephalopods are all discussed. Part three concentrates on challenges and successes in closing the life-cycle and hatchery production for selected fish species, including tuna, striped catfish, meagre, and yellowtail kingfish. Finally, part four explores aquaculture hatcheries for conservation and education.With its distinguished editors and international team of expert contributors, Advances in aquaculture hatchery technology is an authoritative review of the field for hatchery operators, scientists, marine conservators and educators.

  • Advances in Virus Research

    • 1 Edición
    • Volumen 85
    • Karl Maramorosch + 1 más
    • Inglés
    Published since 1953, Advances in Virus Research covers a diverse range of in-depth reviews providing a valuable overview of the current field of virology.

  • Immunopharmacology

    • 1 Edición
    • Volumen 66
    • David J Webb
    • Inglés
    This new volume of Advances in Pharmacology explores the current state of Alzheimer's disease research and therapeutics. Chapters cover such topics as the B cell targeted therapies, Lymphotoxin family receptors in inflammation, and allergic inflammation and thymic stromal lymphopoietin. With a variety of chapters and the best authors in the field, the volume is an essential resource for pharmacologists, immunologists and biochemists alike.

  • Mechanisms of Morphogenesis

    • 2 Edición
    • Jamie A. Davies
    • Inglés
    Morphogenesis is the set of processes that generate shape and form in the embryo--an important area within developmental biology. An exciting and up-to-the-minute account of the very latest research into the factors that create biological form, Mechanisms of Morphogenesis, second edition is a text reference on the mechanisms of cell and tissue morphogenesis in a diverse array of organisms, including prokaryotes, animals, plants and fungi. By combining hard data with computer modeling, Mechanisms of Morphogenesis, second edition equips readers with a much broader understanding of the scope of modern research than is otherwise available. The book focuses on the ways in which the genetic program is translated to generate cell shape, to direct cell migration, and to produce the shape, form and rates of growth of the various tissues. Each topic is illustrated with experimental data from real systems, with particular reference to gaps in current knowledge and pointers to future

  • Advances in Genetics

    • 1 Edición
    • Volumen 81
    • Inglés
    The field of genetics is rapidly evolving, and new medical breakthroughs are occurring as a result of advances in our knowledge of genetics. This series continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines.

  • Methods in Protein Design

    • 1 Edición
    • Volumen 523
    • Inglés
    This new volume of Methods in Enzymology continues the legacy of this premier serial by containing quality chapters authored by leaders in the field. This volume covers methods in protein design and it has chapters on such topics as protein switch engineering by domain insertion, evolution based design of proteins, and computationally designed proteins.

  • Pharmacogenomics

    Challenges and Opportunities in Therapeutic Implementation
    • 1 Edición
    • Yui-Wing Francis Lam + 1 más
    • Inglés
    Pharmacogenomics: Challenges and Opportunities in Therapeutic Implementation includes discussions and viewpoints from the academic, regulatory, pharmaceutical, clinical, socio-ethical and economic perspectives. Each chapter presents an overview of the potential or opportunity within the areas discussed and also outlines foreseeable challenges and limitations in moving pharmacogenomics into drug development and direct therapeutic applications. This edited book contains review questions for a more in-depth analysis of the implications of pharmacogenomics and discussion points to generate ideas on best to move the field forward. Clinical pearls and case studies are used to illustrate real-life experiences and both successful and unsuccessful applications. Tables, figures, and annotations are included throughout the book to facilitate understanding and further reference.

  • In Situ Molecular Pathology and Co-Expression Analyses

    • 1 Edición
    • Gerard J. Nuovo
    • Inglés
    In Situ Molecular Pathology and Co-Expression Analyses explains, in easy-to-understand language, simplified ways of understanding and performing in situ hybridization and immunohistochemistry tests. The book also focuses on straightforward protocols used to simultaneously detect two or more proteins/nucleic acids within intact tissue by doing co-expression analyses. The fields of in situ hybridization and immunohistochemistry have expanded rapidly due to the use of computer-based analysis. To get the most out of these automated platforms, researchers and diagnostic biomedical investigators must have a solid understanding of the basics of in situ-based tests, protocols, and regimens for troubleshooting. Practicing molecular pathologists, clinical chemists, and toxicologists, as well as clinicians and researchers in training, will benefit from this book's clear presentation of protocols and theoretical framework.

  • Nutritional Benefits of Kiwifruit

    • 1 Edición
    • Volumen 68
    • Inglés
    Kiwifruit have long been known as a decorative and exotic fruit that can be used in desserts and fresh fruit collations. What is less well known is that kiwifruit contain a range of constituents with valuable health-beneficial properties. These range from high levels of high-impact vitamin C to enzymes that assist with digestion, and polysaccharides that promote gut health. This volume for the first time brings together all the known health and nutrition benefits of kiwifruit in a series of chapters written by authors who are authorities in their fields.

  • Food Industry Wastes

    Assessment and Recuperation of Commodities
    • 1 Edición
    • Maria R. Kosseva + 1 más
    • Inglés
    Food Industry Wastes: Assessment and Recuperation of Commodities presents emerging techniques and opportunities for the treatment of food wastes, the reduction of water footprint, and creating sustainable food systems. Written by a team of experts from around the world, this book provides a guide for implementing bioprocessing techniques. It also helps researchers develop new options for the recuperation of these wastes for community benefit. More than 34 million tons of food waste was generated in the United States in 2009, at a cost of approximately $43 billion. And while less than three percent of that waste was recovered and recycled, there is growing interest and development in recovering and recycling food waste. These processes have the potential not only to reduce greenhouse gases, but to provide energy and resources for other purposes. This book examines these topics in detail, starting with sources, characterization and composition of food wastes, and development of green production strategies. The book then turns to treatment techniques such as solid-state fermentation and anaerobic digestion of solid food waste for biogas and fertilizer. A deep section on innovative biocatalysts and bioreactors follows, encompassing hydrogen generation and thermophilic aerobic bioprocessing technologies. Rounding out the volume are extensive sections on water footprints, including electricity generation from microbial fuel cells (MFCs), and life cycle assessments.

  • The Epidemiology of Plasmodium vivax: History, Hiatus and Hubris, Part B

    • 1 Edición
    • Volumen 81
    • Inglés
    First published in 1963, Advances in Parasitology contains comprehensive and up-to-date reviews in all areas of interest in contemporary parasitology. Advances in Parasitology includes medical studies on parasites of major influence, such as Plasmodium falciparum and trypanosomes. The series also contains reviews of more traditional areas, such as zoology, taxonomy, and life history, which shape current thinking and applications. Eclectic volumes are supplemented by thematic volumes on various topics, including control of human parasitic diseases and global mapping of infectious diseases.

  • Drug Stability for Pharmaceutical Scientists

    • 1 Edición
    • Thorsteinn Loftsson
    • Inglés
    Drug Stability for Pharmaceutical Scientists is a clear and easy-to-follow guide on drug degradation in pharmaceutical formulation. This book features valuable content on both aqueous and solid drug solutions, the stability of proteins and peptides, acid-base catalyzed and solvent catalyzed reactions, how drug formulation can influence drug stability, the influence of external factors on reaction rates and much more. Full of examples of real-life formulation problems and step-by-step calculations, this book is the ideal resource for graduate students, as well as scientists in the pharmaceutical and related industries.

  • Obesity

    • 1 Edición
    • Volumen 91
    • Inglés
    First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. The Editorial Board now reflects expertise in the field of hormone action, vitamin action, X-ray crystal structure, physiology and enzyme mechanisms. Under the capable and qualified editorial leadership of Dr. Gerald Litwack, Vitamins and Hormones continues to publish cutting-edge reviews of interest to endocrinologists, biochemists, nutritionists, pharmacologists, cell biologists and molecular biologists. Others interested in the structure and function of biologically active molecules like hormones and vitamins will, as always, turn to this series for comprehensive reviews by leading contributors to this and related disciplines. This volume focuses on obesity.

  • G Protein Coupled Receptors

    Modeling, Activation, Interactions and Virtual Screening
    • 1 Edición
    • Volumen 522
    • Inglés
    This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers G protein coupled receptors, and includes chapters on such topics as GPCR modelling, interactions with other molecules, virtual screening and GPCR activation.

  • Handbook of Biologically Active Peptides

    • 2 Edición
    • Abba Kastin
    • Inglés
    Handbook of Biologically Active Peptides, Second Edition, is the definitive, indispensable reference for peptide researchers, biochemists, cell and molecular biologists, neuroscientists, pharmacologists, and endocrinologists. Its chapters are designed to be a source for workers in the field and enable researchers working in a specific area to examine related areas outside their expertise. Peptides play a crucial role in many physiological processes, including actions as neurotransmitters, hormones, and antibiotics. Research has shown their importance in such fields as neuroscience, immunology, pharmacology, and cell biology. The second edition of Handbook of Biologically Active Peptides presents this tremendous body of knowledge in the field of biologically active peptides in one single reference. The section editors and contributors represent some of the most sophisticated and distinguished scientists working in basic sciences and clinical medicine.

  • G Protein Coupled Receptors

    Trafficking and Oligomerization
    • 1 Edición
    • Volumen 521
    • Inglés
    This new volume of Methods in Enzymology continues the legacy of this premier serial by containing quality chapters authored by leaders in the field. This volume covers G protein coupled receptors and includes chapters on such topics as G protein-coupled receptor trafficking motifs, structure-based virtual screening, and automation-friendly high throughput assays for identification of pharmacoperone drugs.

  • PAKs, RAC/CDC42 (p21)-activated Kinases

    Towards the Cure of Cancer and Other PAK-dependent Diseases
    • 1 Edición
    • Hiroshi Maruta
    • Inglés
    This book covers a variety of cutting-edge basic and clinical PAK research ranging from laboratory benches to hospital beds. The goal of this book is to inspire not only biomedical research scientists and university students, but also a variety of patients who suffer from PAK-dependent diseases and clinical doctors who try to cure or delay these PAK-dependent diseases.This book consists of 9 chapters which deal with different aspects of this kinase. These chapters are written by more than two dozen world-leading PAK experts. Each of these will provide updated biomedical information as well as future insight to a wide range of readers who are interested in this unique kinase and both its pathological and physiological roles as well as its functional evolution from its ancestral origins.

  • Open Innovation in the Food and Beverage Industry

    • 1 Edición
    • Marian Garcia Martinez
    • Inglés
    Food and beverage companies are increasingly choosing to enhance internal idea development by pursuing an ‘open innovation’ approach, allowing the additional exploitation of external ideas and paths to market. Drawing on a range of important case studies, Open innovation in the food and beverage industry investigates the challenges and opportunities afforded by the incorporation of open innovation into the food industry.Part one provides a comprehensive overview of the changing nature of innovation in the food and drink industry, acknowledging trends and considering the implications and impact of open innovation. Part two then reviews the role of partners and networks in open innovation, with collaboration, co-creation of value with consumers, the effectiveness of cluster organizations and the importance of network knowledge all discussed, before part three goes on to explore the establishment and varied management aspects of open innovation partnerships and networks. Finally, open-innovation tools, processes and managerial frameworks are the focus of part four, with discussion of the development, application and psychology of a range of initiatives.With its distinguished editor and international team of expert contributors, Open innovation in the food and beverage industry is a unique guide to the implementation and management of open innovation for all food industry professionals involved in management, research and product development, as well as academics with an interest in open innovation across all industries.

  • Ligand Efficiency Indices for Drug Discovery

    Towards an Atlas-Guided Paradigm
    • 1 Edición
    • Celerino Abad-Zapatero
    • Inglés
    The purpose of Ligand Efficiency Indices for Drug Discovery: Towards an Atlas-Guided Paradigm is to introduce in a concise and self-contained form the concepts, ideas, applications and examples of efficiency-driven drug discovery to the biomedical community at large. The book emphasizes the use of 'new variables' and more objective numerical methods to drive drug discovery in an encompassing way. These 'new variables' are based on Ligand Efficiency Indices (LEIs) formulated in a way that permits mapping Chemico-Biological Space (CBS) in an Atlas-like representation. It provides a practical and timely discussion of the concepts, ideas, applications and examples of efficiency-driven drug discovery. This book emphasizes the use of a graphical representation and objective numerical methods to drive drug discovery more effectively. It presents the definition of LEIs and the corresponding efficiency planes within an atlas-like environment to provide a robust graphical and numerical framework for medicinal chemists and drug-discoverers.

  • Accurate Results in the Clinical Laboratory

    A Guide to Error Detection and Correction
    • 1 Edición
    • Amitava Dasgupta + 1 más
    • Inglés
    This practical, easy-to-use guide, named to Doody’s Core Titles 2013, addresses interference issues in all laboratory tests, including patient epigenetics, process of specimen collection, enzymes, biomarkers. Clinicians and laboratory scientists can therefore rely on one reference which speaks to both their needs of accurate specimen analysis and optimal patient care. Erroneous hospital and pathology laboratory results can be confusing and problematic, especially in acute care situations. While some factors creating interference, can be identified in the laboratory, detecting many others is often dependent on clinical details unavailable to the laboratory scientists or pathologists. Therefore, clinicians must become proficient in identifying such erroneous reports, and working with pathologists and laboratory scientists so that they can understand the source of such interferences, correct the results, and then decide what course of action must be followed for proper patient management.

  • The Psychology of Learning and Motivation

    • 1 Edición
    • Volumen 58
    • Inglés
    The Psychology of Learning and Motivation series publishes empirical and theoretical contributions in cognitive and experimental psychology, ranging from classical and instrumental conditioning to complex learning and problem solving.

  • The Immunoassay Handbook

    Theory and Applications of Ligand Binding, ELISA and Related Techniques
    • 4 Edición
    • David Wild
    • Inglés
    The fourth edition of The Immunoassay Handbook provides an excellent, thoroughly updated guide to the science, technology and applications of ELISA and other immunoassays, including a wealth of practical advice. It encompasses a wide range of methods and gives an insight into the latest developments and applications in clinical and veterinary practice and in pharmaceutical and life science research. Highly illustrated and clearly written, this award-winning reference work provides an excellent guide to this fast-growing field. Revised and extensively updated, with over 30% new material and 77 chapters, it reveals the underlying common principles and simplifies an abundance of innovation. The Immunoassay Handbook reviews a wide range of topics, now including lateral flow, microsphere multiplex assays, immunohistochemistry... practical ELISA development, assay interferences, pharmaceutical applications, qualitative immunoassays, antibody detection and lab-on-a-chip. This handbook is a must-read for all who use immunoassay as a tool, including clinicians, clinical and veterinary chemists, biochemists, food technologists, environmental scientists, and students and researchers in medicine, immunology and proteomics. It is an essential reference for the immunoassay industry. Provides an excellent revised guide to this commercially highly successful technology in diagnostics and research, from consumer home pregnancy kits to AIDS testing.www.immunoas... is a great resource that we put a lot of effort into. The content is designed to encourage purchases of single chapters or the entire book. David Wild is a healthcare industry veteran, with experience in biotechnology, pharmaceuticals, medical devices and immunodiagnostics, which remains his passion. He worked for Amersham, Eastman-Kodak, Johnson & Johnson, and Bristol-Myers Squibb, and consulted for diagnostics and biotechnology companies. He led research and development programs, design and construction of chemical and biotechnology plants, and integration of acquired companies. Director-level positions included Research and Development, Design Engineering, Operations and Strategy, for billion dollar businesses. He retired from full-time work in 2012 to focus on his role as Editor of The Immunoassay Handbook, and advises on product development, manufacturing and marketing.

  • Animal Metamorphosis

    • 1 Edición
    • Volumen 103
    • Inglés
    This new volume of Current Topics in Developmental Biology covers recent progresses in our understanding of animal metamorphosis. Over a dozen of leading experts reviews studies ranging from morphological, molecular to genetic analyses of metamorphosis in a broad spectrum of animals, including insects, fish. Topics include molecular evolution in metamorphosis, the synthesis and function of hormones in regulating metamorphic timing and rate, regulation and function of nuclear hormone receptors, neuroendocrine control of metamorphosis, tissue specific metamorphic events such as autophagy and stem cell development, and applications of genome-wide analysis technologies for studying metamorphosis.

  • G Protein Coupled Receptors

    Structure
    • 1 Edición
    • Volumen 520
    • Inglés
    This new volume of Methods in Enzymology continues the legacy of this premier serial by containing quality chapters authored by leaders in the field. This volume covers G protein coupled receptors and includes chapters on such topics as post-translation modification of GPCR in relationship to biased agonism, structure-based virtual screening, and GPCR oligomerization in the brain.

  • Fish Physiology: Euryhaline Fishes

    • 1 Edición
    • Volumen 32
    • Stephen D. McCormick + 2 más
    • Inglés
    The need for ion and water homeostasis is common to all life. For fish, ion and water homeostasis is an especially important challenge because they live in direct contact with water and because of the large variation in the salt content of natural waters (varying by over 5 orders of magnitude). Most fish are stenohaline and are unable to move between freshwater and seawater. Remarkably, some fishes are capable of life in both freshwater and seawater. These euryhaline fishes constitute an estimated 3 to 5% of all fish species. Euryhaline fishes represent some of the most iconic and interesting of all fish species, from salmon and sturgeon that make epic migrations to intertidal mudskippers that contend with daily salinity changes. With the advent of global climate change and increasing sea levels, understanding the environmental physiology of euryhaline species is critical for environmental management and any mitigative measures. This volume will provide the first integrative review of euryhalinity in fish. There is no other book that focuses on fish that have the capacity to move between freshwater and seawater. The different challenges of salt and water balance in different habitats have led to different physiological controls and regulation, which heretofore has not been reviewed in a single volume.

  • Decision Making: Neural and Behavioural Approaches

    • 1 Edición
    • Volumen 202
    • Inglés
    This well-established international series examines major areas of basic and clinical research within neuroscience, as well as emerging and promising subfields.This volume explores interdisciplinary research on decision making taking a neural and behavioural approach

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