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Elsevier

Libros en Ciencias de la Vida

  • The Epidemiology and Prevention of Childhood Injuries

    An Overview
    • 1 Edición
    • Hamid Soori + 1 más
    • Inglés
    The Epidemiology and Prevention of Childhood Injuries: An Overview takes a comprehensive approach to understanding and addressing childhood injuries. Integrating global research and practice, the book aims to significantly advance injury prevention among children. With detailed chapters on epidemiological measures, risk factors, and prevention strategies, it offers a thorough review of childhood injury contexts. The book covers injuries related to transport, home, school, play, sports, workplace, violence, and disasters. It discusses first aid essentials, accountability, and collaboration, concluding with methodologies, data collection techniques, and outcome assessments. This resource is invaluable for researchers, pediatricians, public health experts, and policymakers seeking to protect children.

  • Advances in Agronomy

    • 1 Edición
    • Volumen 192
    • Inglés
    Advances in Agronomy, Volume 192, the latest release in this leading reference on agronomy, contains a variety of updates and highlights new advances in the field, each written by an international board of authors. Chapters in this new release include The USDA Desert Soil-Geomorphology Project (1957-1972), Electrochemical transformations of nutrients in the soils vis-a-vis geochemistry of potentially and readily available nutrients under different soil moisture regimes: a review, Current approaches in the characterization and quantification of soil crusts, Soil fauna impacts on carbon cycling in managed grasslands: a review, Deciphering PGPR Mechanisms in Saline Soils: Enhancing Plant Productivity, and much more. Other chapters cover Interventions of microbial fuel cell technology for management of agricultural residues: Challenges and future perspectives.

  • Enzymes of Polyamine Metabolism

    • 1 Edición
    • Volumen 715
    • Inglés
    Enzymes of Polyamine Metabolism, Volume 715 highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Convergence of MYC and the hypusine circuits in the control of metabolism, HDAC10 structure and enzymology, TR-FRET Assay for Profiling HDAC10 Inhibitors and PROTACs, Polyamine Transport Inhibitors: Methods and caveats associated with measuring polyamine uptake in mammalian cells, Evaluation of platinum drug toxicity resulting from polyamine catabolism, Measurements of acrolein adducts resulting from polyamine catabolism, Alterations in polyamine metabolism induced by the pathogen Helicobacter pylori: implications for gastric inflammation and carcinogenesis, and much more.Other sections delve into Molecular and biochemical analysis of eIF5A, Analysis of in vivo SMOX activity, Structure and role of ATP13A2 in polyamine transport, Analysis of Translational Regulation Using Polysome Profiling and Puromycin Incorporation, Targeting polyamine metabolism in an ex vivo prostatectomy model, Development and characterization of a Drosophila model of SRS, Monitoring ODC activity and polyamines in Bachmann-Bupp syndrome patient biological samples, Gene replacement therapy to restore polyamine metabolism, Investigation of polyamine metabolism in bone homeostasis, Collection, preparation, and biobanking of clinical specimens for polyamine analysis, and many other topics.

  • Biosafety Level 4 (BSL4) – Virus Research at the Highest Level of Biosafety and Biosecurity

    • 1 Edición
    • Volumen 121
    • Inglés
    Biosafety Level 4 (BSL4) – Virus Research at the Highest Level of Biosafety and Biosecurity, Volume 121 highlights new advances, with this new volume presenting interesting chapters on highly important topics such as Molecular virulence determinants of human-pathogenic filoviruses, Mucosal Sudan virus infection results in a lethal disease in ferrets with previous Lloviu virus infection not providing cross-protection, Transcriptional signatures of Ebola and Marburg virus infection in a Bat-Immune-System (BIS) mouse model, Divergences in the microbial inactivation pattern between vaporized hydrogen peroxide and aerosolized peracetic acid by dry fogging, and much more.Other chapters cover Molecular expressions in tissues and blood following Reston and Bundibugyo virus infection in swine, De novo rescue of new BSL4 henipaviruses - from sequence to pathogen, Semi-automated diagnostic RT-PCR as a screening assay for antiviral compounds in a 96-well format against highly pathogenic RNA viruses, and Relevance of studying virus – natural reservoir interactions: SNV in deer mice and LASV in Mastomys natalensis.

  • Biochemical Aspects of Metabolic Disorders

    • 1 Edición
    • Muhammad Sajid Hamid Akash + 1 más
    • Inglés
    Biochemical Aspects of Metabolic Disorders offers a comprehensive exploration of the intricate biochemical mechanisms and/or pathways underlying a wide array of metabolic disorders. From the genetic basis of inherited metabolic conditions to the environmental factors impacting metabolic dysregulation, each chapter investigates the molecular insights essential for understanding and managing these complex diseases. Covering topics such as carbohydrate and lipid metabolism disorders, amino acid catabolism, hepatic and renal metabolism, mitochondrial dysfunction, pediatric obesity, and diagnostic approaches, this book will serve as a requisite resource for researchers, clinicians, and students alike looking for unravel the biochemical intricacies of metabolic disorders.

  • Culinary Nutrition

    The Science and Practice of Healthy Cooking
    • 2 Edición
    • Jacqueline B. Marcus
    • Inglés
    Culinary Nutrition: The Science and Practice of Healthy Cooking, Second Edition is one of the first textbooks specifically written to bridge the relationship between food science, nutrition, and culinology as well as consumer choices for diet, health, and enjoyment. The book uses a comprehensive format with real-life applications, recipes, and color photographs of finished dishes to emphasize the necessity of sustainably deliverable, health-beneficial, and taste-desirable products.The book includes pedagogical elements to enhance and reinforce learning opportunities; explores which foods and beverages involve the optimum nutritional values for dietary and health needs; includes specific dietary requirements throughout the lifecycle; and examines how foods and beverages are produced. The fully revised second edition includes updated dietary and health guidelines and recommendations; more vegan, vegetarian, and plant-based meals; updated protein, carbohydrate, fat, vitamin and mineral recommendations; environmental and sustainability considerations; and much more.

  • Disparities in Pediatric Endocrine Disorders, An Issue of Endocrinology and Metabolism Clinics of North America

    • 1 Edición
    • Volumen 54-2
    • Terri H. Lipman + 1 más
    • Inglés
    In this issue of Endocrinology and Metabolism Clinics, guest editors Drs. Terri Lipman and Ingrid Libman bring their considerable expertise to the topic of Disparities in Pediatric Endocrine Disorders. Top pediatric endocrine experts discuss health disparities present in pediatric endocrinology and metabolism care, with the goal of achieving more equitable patient care in the areas of diabetes, bone disease, puberty, and thyroid disease, and more.

  • Molecular Medicine and Biomedical Research in the Era of Precision Medicine

    New Technologies and Personalized Drug Therapies for Patient Care
    • 1 Edición
    • Ranbir Chander Sobti + 4 más
    • Inglés
    Molecular Medicine and Biomedical Research in the Era of Precision Medicine: New Technologies and Personalized Drug Therapies for Patient Care provides researchers with an extensive overview of recent advances in molecular biology impacting the development of targeted therapies. The book delivers insights into the pathobiological and pathogenetic mechanisms of various diseases, providing a detailed study of the latest personalized interventions to be implemented across such conditions. It covers a range of technologies, including RNA-sequencing, AI, Machine Learning, gene therapy, omics and nanotechnology, delving into their clinical applications across various diseases.The book also tackles targeted treatments of different disease types, including acute, chronic, infectious and noncommunicable diseases. Future perspectives are also covered, providing an in-depth study across molecular medicine, drug discovery and delivery, disease diagnosis and prevention, and therapeutic interventions, and acting as an invaluable interdisciplinary reference for researchers across the biomedical sciences.

  • Patient Safety and Health Care Quality in Vulnerable Hospitalised Populations

    • 1 Edición
    • Theresa A. Mikhailov
    • Inglés
    Patient Safety and Health Care Quality in Vulnerable Hospitalised Populations consolidates existing knowledge and research on patient safety and healthcare quality within vulnerable populations. It provides a comprehensive reference work, offering invaluable insights into this critical area. While information on related topics is scattered across various medical journals, this book bridges the accessibility gap by bringing this knowledge together in one authoritative volume. With a specific focus on hospitalized children and elderly adults, the book tackles a global issue that is particularly relevant in low-resource settings.In addition, it endeavors to address the unique challenges confronted by these populations, equipping stakeholders with vital information and strategies to better serve them. By exploring patient safety and healthcare quality, users will find this to be an invaluable resource that will shape the future of care provision for vulnerable populations.

  • Handbook of Milk Production, Quality and Nutrition

    • 1 Edición
    • Tanmoy Rana
    • Inglés
    Handbook of Milk Production, Quality and Nutrition emphasizes new applications to promote healthy milk production, processing, and product development in the milk industry, highlighting the role clean milk has in the prevention of health and disease. Sections cover the general aspects of milk production and its environmental impact on animal health, explain milk’s global nutritional appeal and its role as a source of both macro and micronutrients for human health, address issues of lactose intolerance and how this ailment is perceived globally, and discuss milk’s relevance on bone, ocular, and gut health.Finally, the book brings awareness to milk’s microbial pathogens, toxins, and heavy metals, and health concerns, while also updating on regulatory health and nutrition claims and recent legislative developments.

  • Roles of Osmolytes in Changing Environment

    • 1 Edición
    • Azamal Husen
    • Inglés
    Roles of Osmolytes in Changing Environment is the only available comprehensive coverage of the recent advances in our understanding on how plants coordinate with different osmolytes, and their role in improving the tolerance of plants under stress conditions. Including insights of their effect against cold, heat, UV, submergence, wounding, extremes of temperature, drought, salinity, high metal concentrations, water logging, pollution, and nutrient deficiency stress, the book also explains the role of various osmolytes against phytopathogenic viruses, bacteria, fungi, algae, nematodes, and insects. Understanding the significance of different osmolytes for sustainable plant growth and production under diverse stress situations is increasingly important for both crop and non-crop plants. This volume presents the latest research and inspires further research toward osmolyte use in developing stress tolerance in plants. Roles of Osmolytes in Changing Environment is a valuable resource for scientists, researchers and advanced level students working in plant biology, plant physiology, plant stress physiology, plant biochemistry, botanical or crop sciences, environmental sciences, and ecological sciences.

  • Ultra Widefield Imaging of the Retina

    • 1 Edición
    • Maria Vittoria Cicinelli + 1 más
    • Inglés
    Ultra Widefield Imaging of the Retina covers basic anatomy and physiology of the retina, providing the technical aspects of ultra widefield retinal imaging that give readers a strong grounding in the discipline’s central tenets. The book provides a comprehensive view of the peripheral retina, enabling better detection of pathology and more accurate assessment of disease progression. It fills the knowledge gap among healthcare professionals with regard to principles, procedural aspects, and clinical applications of these innovations. In essence, anyone seeking in-depth information on imaging and the treatment of vascular chorioretinal disorders, inflammatory disorders, and chorioretinal tumors will find it here.New imaging modalities, improved image quality, and enhanced analysis techniques have proven valuable tools in the diagnosis and management of retinal diseases, hence this book will serve as a resource for clinicians and researchers to stay up-to-date in this rapidly evolving field.

  • Veterinary Toxicology

    Basic and Clinical Principles
    • 4 Edición
    • Ramesh C. Gupta
    • Inglés
    Veterinary Toxicology: Basic and Clinical Principles, Fourth Edition is a unique single reference that provides a comprehensive overview on the basic principles of veterinary toxicology to any student at the DVM, MS, or PhD level while also continuing to serve as a clinical reference for practitioners. The book thoroughly updates toxicologists and advanced students on the newest approaches for diagnosing poisoning cases in all animals from chemicals, plants, and accidental or malicious intents. Many chapters are provided on topics not covered in any previous books, such as target organ toxicity, radiation and radioactive materials, FDA regulatory issues, and ethics in veterinary toxicology.Completel... revised and updated to include the most recent developments in the field animal toxins, toxicokinetics mechanism of action, toxicity, and treatment, this book is an essential resource for researchers, practicing veterinary toxicologists, advanced students in toxicology, poison control centers, as well as environmentalists, marine biologists, and animal scientists.

  • Biocatalysis

    • 1 Edición
    • Volumen 714
    • Inglés
    Biocatalysis, Volume 714 provides a wide range of themes dealing with the identification and application of biocatalysts. This includes various formats such as whole-cell or cell-free biocatalysis as well as immobilized variants. Specific chapters in this new release include Biocatalysis: How to select the proper mode of application, Documentation in biocatalysis and data handling, Mining metagenomes from extremophiles as resource for novel glycoside hydrolases for industrial applications, Functional Metaproteomics, Sequence-function relation for the prediction of enzyme properties: A case study on flavin-dependent oxidases, P450 monooxygenase in whole-cell format, and more.Additional sections cover Regio- and Stereospecific oxidation based on di-iron monooxygenases producing whole cells, Recombinant enzyme expression and targeted mutagenesis in Aromatoleum species, C.necator as a model organism for CO2-based biotechnology, Cupriavidus in whole-cell biocatalysis, Whole-cell biocatalysis with Myxobacteria, Streptomyces for natural product formation: Targeted mutagenesis in PKS, Reductive Amination: Methods for cell-free and whole-cell biocatalysis, Challenges and good practices on transaminase-catalys... synthesis of optically pure amines, W-enzymes in biocatalysis: Chances and difficulties for the user, Atroposelective biocatalysis employing ADHs, Applications of alcohol oxidases, and much more.

  • Clinical Pathophysiology of Hypertension, Diabetes, and Other Stress and Lifestyle Associated Diseases

    • 1 Edición
    • Tetsuya Watanabe
    • Inglés
    Clinical Pathophysiology of Hypertension, Diabetes, and Other Stress and Lifestyle Associated Diseases presents mathematical and physical basis to apply in practice for a better understanding of some common and not so common diseases brough on by stress and lifestyle. Chapters cover new findings in hypertension, arrhythmias, diabetes, nephropathy, and periodontal disease. Written by Dr. Tetsuya Watanabe, President of Watanabe Institute of Mathematical Biology and Watanabe Clinic of Oral Surgery in Hamamatsu, Japan, for clinical doctors, medical research doctors, pathophysiological scientists, pharmaceutical scientists, and biologists and physicists in bioengineering.

  • Nutrición y dietética clínica

    • 5 Edición
    • Jordi Salas-Salvadó + 1 más
    • Español
    Nutrición y dietética clínica se consolida en esta quinta edición como una obra esencial para los profesionales de la salud por su enfoque riguroso y multidisciplinar sobre el tratamiento dietético de las enfermedades relacionadas con la alimentación. Destaca el carácter colaborativo de la obra y su alcance global, ya que cuenta con la experiencia de más de 100 autores españoles e hispanoamericanos, todos ellos médicos, dietistas-nutricioni... o profesionales de otras especialidades relacionadas con la alimentación y la nutrición. Una importante novedad en esta edición es la introducción de un capítulo sobre trastornos de la conducta alimentaria, así como un anexo titulado «Nombres de alimentos en países de habla hispana» que, sin duda, apoya la consolidación de la proyección internacional de este texto, especialmente en países de América Latina, respetando la diversidad cultural y lingüística utilizando los términos propios de cada región para facilitar la compren­sión global. Los directores de la obra, el Prof. Jordi Salas-Salvadó y la Dra. Nancy Babio, junto con las Dras. Anna Bonada, M. Engràcia Saló y Rosa Burgos, y el Dr. Guillermo Cárdenas, han liderado este proyecto con dedicación y compromiso, asegurando la calidad y el rigor científico que han caracterizado Nutrición y dietética clínica desde la primera edición. La nueva edición ofrece acceso al e-book en el que se incluyen preguntas de autoevaluación con respuestas razonadas para fomentar la reflexión y evaluar la comprensión de los contenidos.

  • Sustainable Goat Production in the Changing Climate

    • 1 Edición
    • Veerasamy Sejian + 2 más
    • Inglés
    Sustainable Goat Production in the Changing Climate aims to make the global scientific and academic communities aware of the potential of goats as a livestock of the future. When compared to more popular meat sources like cattle and swine, goats have a lower carbon footprint and can aid in mitigating the effects of climate change, as well as improving food production, poverty and equity issues. This book will discuss the implications of climate change on goat production systems and emphasize the physiological potential of goats to adapt to erratically changing climatic conditions. Furthermore, the book includes chapters on strategies to mitigate the effects of climate change on goat production and highlights novel technologies used to assess the impact of heat stress in goats. Technology transfer strategies and policy-related issues will also be covered.Written and edited by an international team of experts on goats, livestock, animal agriculture, and climate-smart food systems, Sustainable Goat Production in the Changing Climate will appeal to a broad audience, from researchers to livestock specialists, veterinarians, and policymakers in food and sustainability.

  • Small Ruminant Welfare, Production and Sustainability

    • 1 Edición
    • Govind Kannan
    • Inglés
    Small ruminant production, particularly that of sheep and goats, has steadily increased over the years, with goat production alone doubling during the past three decades. Increased public attention to the impact of livestock management methods on animal well-being warrants rigorous research and dissemination of findings to address this issue. Small Ruminant Welfare, Production, and Sustainability focuses on advances in assessing and improving small ruminant well-being and the implications for the sheep and goat sectors worldwide. A variety of assessment systems for small-ruminant wellbeing are considered, including behavior, health, physiology, immunology, productivity, product quality, neural networks, thermal imaging, facial recognition, and artificial intelligence. Current methods and novel management practices are examined as they relate to both animal welfare and improvement of production systems.Small Ruminant Welfare, Production, and Sustainability is a welcome addition to the current body of work the current body of work on small ruminant management systems and welfare. Researchers in the fields of animal science, agricultural science, neuroscience, ethics and veterinary medicine, as well as stakeholders in the small ruminant industry and policymakers will benefit from this multidisciplinary resource.

  • Cholinergic Involvement in Neurodegenerative Diseases

    • 1 Edición
    • Volumen 211
    • A. Claudio Cuello
    • Inglés
    Cholinergic Involvement in Neurodegenerative Diseases, Volume 211 reviews cholinergic function in the brain as it relates to Neurodegenerative disorders. Coverage includes Alzheimer’s, dementia, Down Syndrome, Parkinson’s, Huntington’s, ALS, and more. In addition, the anatomy of the cholinergic system is described as well as the distribution and function of receptors.

  • Protien Aggregation - Part A

    • 1 Edición
    • Volumen 145
    • Inglés
    Protein Aggregation, book provides valuable insights into the factors driving protein aggregation, the impact on cellular function, and the role in various diseases, offering a comprehensive overview for researchers and professionals in the field of biomedicine and biochemistry.

  • Craft Beer

    New Frontiers in Brewing Science
    • 1 Edición
    • Patrizia Romano + 2 más
    • Inglés
    Recently, both researchers and consumers have shown strong and growing interest in craft beer, which is characterized by its small batches, local breweries, and unique varieties. Craft Beer: New Frontiers in Brewing Science provides a comprehensive picture of the craft beer market, history and legal definition, brewing processes, and the qualities and styles of the end product. It emphasizes traditional and innovative microbial resources involved in the fermentation process, as well as safety, nutrition, and emerging problems, such as the sustainability of the production process.Craft Beer: New Frontiers in Brewing Science is the first and only scientific text to comprehensively summarize this exciting field. Researchers and students in interested brewing science, as well as industry specialists from beer companies will all benefit from this unique resource.

  • Emerging Trends and Applications of Deep Learning for Biomedical Data Analysis

    • 1 Edición
    • Smita Sharma + 3 más
    • Inglés
    Emerging Trends and Applications of Deep Learning for Biomedical Data Analysis introduces the latest emerging trends and applications of deep learning in biomedical data analysis. This book delves into various use cases where deep learning is applied in industrial, social, and personal contexts within the biomedical domain. By gaining a comprehensive understanding of deep learning in biomedical data analysis, readers will develop the skills to critically evaluate research papers, methodologies, and emerging trends. In 11 chapters, this book provides insights into the fundamentals of the latest research trends in the applications of deep learning in biosciences. With several case studies and use cases, it familiarizes the reader with a comprehensive understanding of deep learning algorithms, architectures, and methodologies speci cally applicable to biomedical data analysis. This title is an ideal reference for researchers across the biomedical sciences.

  • Handbook of Translational Transcriptomics

    Research, Protocols and Applications
    • 1 Edición
    • Anton Buzdin
    • Inglés
    Handbook of Translational Transcriptomics: Research, Protocols and Applications provides a comprehensive overview of the field of transcriptomics. With an emphasis on the various protocols and techniques available for investigation, it acts as a practical guide to researchers for implementing their own investigations in the field.This book begins with an overview of the past, present, and potential approaches in the field of transcriptomics, with discussions of choosing the correct approach based on the research needed. It also highlights the pros and cons of each approach. Following this, it explores techniques and protocols for investigating specific approaches focusing on RNA sequencing, expression arrays, and gene expression. It then delves into data analysis and offers recommendations, guidelines, and approaches related to data interpretation. This book also considers the translation of transcriptomics to clinical use and applications in molecular diagnostics, biomarkers in medicine, and personalized medicine specific to oncology, as well as biotechnology for pharmaceutical research.Handbook of Translational Transcriptomics: Research, Protocols and Applications is a detailed reference that provides a complete view of transcriptomics, ranging from methods to handling data and medical applications. This book is an invaluable guide for researchers working across molecular biology, genetics, bioinformatics and related fields, as well as graduate and PhD students in these areas.

  • Great American Diseases

    Their Effects on the Course of North American History
    • 2 Edición
    • Ian R. Tizard + 1 más
    • Inglés
    Great American Diseases: Their Effects on the Course of North American History, Second Edition covers significant disease epidemics that have shaped North American history, from the arrival of Smallpox with the first Europeans to the COVID-19 pandemic. It includes an introduction to the basic science of diseases, the history of vaccination in the Americas, and discussions on various diseases and their pathogens. The text concludes with a chapter on notable animal disease outbreaks. Delving deeper, the book provides engaging chapters on the societal impacts of epidemics and the evolution of medical responses.It presents a fascinating intersection of microbiology, immunology, and epidemiology enriched with contemporary outbreak examples and educational resources for biomedical students.

  • Human-Centric Integration of 6G-Enabled Technologies for Modern Society

    Fundamentals, Applications, Analysis and Challenges
    • 1 Edición
    • Amit Kumar Tyagi + 1 más
    • Inglés
    Human-Centric Integration of 6G-Enabled Technologies for Modern Society: Fundamentals, Applications, Analysis and Challenges serves as a comprehensive reference, addressing the information needs of professionals by providing deep information about the fundamentals and applications of 6G, enabling them to make informed decisions in the dynamic landscape of advanced communication technologies. In the 23 chapters, this book introduces the reader to the 6G technology, the evolution of wireless communication, and the integration of artificial intelligence; provides the use cases and applications of 6G technology and the insights into the challenges, future trends, and emerging technologies; and includes the applications of 6G technology in remote healthcare services, patient monitoring, and medical diagnostics.Human-Ce... Integration of 6G-Enabled Technologies for Modern Society: Fundamentals, Applications, Analysis and Challenges redefines the way we connect, communicate, and collaborate with emerging technologies in this smart era of 6G technology. The title benefits from a collective wealth of knowledge and perspectives. This diversity enriches the content, providing readers with insights from various angles, setting it apart from publications authored or edited by a limited number of individuals.

  • Advances in 3D and 4D Printing of Medical Robots and Devices

    • 1 Edición
    • Ankit Sharma + 1 más
    • Inglés
    Advances in 3D and 4D Printing of Medical Robots and Devices presents the most recent innovative breakthroughs in smart manufacturing and biomedical engineering to help enhance knowledge and expertise in 3D/4D printing technologies and advancements in biomedical applications through robotics and medical devices. This book highlights the usage and importance of 3D/4D printing-based prototyping as well as the manufacturing of robotic elements such as energy generators, morphology control, and novel design strategies. This book will help readers to pursue contemporary insights into currently ongoing practices in biomedical and mechatronic engineering including the fabrication of actuators manufacturing; muscles, vibration dampers, bio-inspired structures, pre-surgical and post-surgical tooling, medical assistance robots, drug delivery, microfluidic, and wearable electronics. Academic scholars, manufacturing scientists, and commercial manufacturers of bio-devices and medical robotics will find this book to be useful in adopting competent biomaterials as well as innovative techniques for applications in biomedical engineering.

  • The Use of Radioautography in Investigating Protein Synthesis

    • 1 Edición
    • C. P. Leblond + 1 más
    • Inglés
    The Use of Radioautography in Investigating Protein Synthesis is a collection of papers that discusses the tracing of labeled proteins through photographic emulsion, particularly radioautography or autoradiography. The papers discuss proteins at the site of their synthesis, their subsequent migration through the cell, their secretions, and the formation of the basement lamella in salamanders. One paper outlines the primary aims in specimen preparation for electron microscope autoradiographic techniques and the procedures to achieve them. Another paper reports on migrating proteins (CNP) and nonmigrating proteins of the Amoeba proteus nucleus in which nonmigrating proteins are sedimentable by centrifugation in situ in the nucleus. One paper investigates the extent of protein synthesis for cell renewal in thoracic duct lymphocytes (TDL) or that for export or intracellular turnover. The protein synthesized by the large cell population in TDL is associated with mitosis and cell renewal. A major portion of that synthesized by the medium cells (80 per cent) and practically all of that produced by small cells are for purposes other than cell renewal. The collection can prove beneficial to biochemists, micro-biologists, bio-physicists, cytologists, histologists, pathologists, cellular researchers, and academicians involved in the study of cellular biology.

  • Protides of the BIological Fluids

    Proceedings of the Thirty-Sixth Colloquium, 1989
    • 1 Edición
    • H. Peeters + 1 más
    • Inglés
    An International Review Series Devoted to Proteins and Related Studies, Volume 36: Protides of the Biological Fluids documents the proceedings of the 36th Colloquium held in 1989. This book discusses the structure of the human IgA subclasses and allotypes; comparison of normal values of IgG subclasses; and structural genetic alterations in Ig subclass deficiencies. The interleukin cascade for the regulation of IgA synthesis and immune responses; phenotypic and functional changes during T cell activation; and flow cytometric analysis of sequential tumor biopsies during therapy are also elaborated. This text likewise covers the serum and fecal proteins during Crohn's disease and isolation and properties of apolipoprotein A for therapeutic use. This publication is recommended for students and specialists conducting work on the study of proteins and techniques of their isolation, purification, and immunological quantitation.

  • Circulating Tumor Cells, From Biotech Innovation to Clinical Utility Part B

    • 1 Edición
    • Volumen 392
    • Inglés
    Circulating Tumor Cells, From Biotech Innovation to Clinical Utility Part B, Volume 392 in the International Review of Cell and Molecular Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Circulating Tumor Cells in Lung Cancer: integrating stemness and heterogeneity to improve clinical utility, Multi-omic Features and Clustering Phenotypes of Circulating Tumor Cells Associated with Metastasis and Clinical Outcomes, CTCs in CRC: updates, Proteomics and post-translational modification analysis in CTCs, Latest advances of CTC studies in prostate cancer, and Epigenetics and CTCs: new biomarkers and impact on tumor biology.

  • Smart Organ-on-Chip Devices

    Dynamic Microfluidic Systems for Cell Culture
    • 1 Edición
    • Tiago Albertini Balbino + 2 más
    • Inglés
    Smart Organ-on-Chip Devices: Dynamic Microfluidic Systems for Cell Culture discusses the concepts to engineer functional stimuli responsive organotypic-on-chip devices and its application in several fields, including drug development, disease modeling, personalized medicine, and tissue engineering. Groundbreaking studies are presented throughout the book sections to reinforce the importance of adding more reliable and robust in vitro platforms able to closely emulate the dynamism of human physiology.The authors present new information regarding in silico studies of cell spheroids within microfluidic devices, as well as step-by-step guidance on key procedures. Written for researchers, practitioners and students using microfluidic devices as platforms, by well-respected scientists from both academia and industry.

  • The Origins of Life

    From Abiotic Chemistry to the First Cells
    • 1 Edición
    • Karl Niklas + 2 más
    • Inglés
    The Origins of Life: From Abiotic Chemistry to the First Cells is an essential textbook that tackles one of the greatest mysteries in science, how inanimate matter evolved into the first living things. The book takes an interdisciplinary approach, delving into the basic principles of the earth’s chemistry, the formation of pre-cellular entities, and the acquisition of chemical complexity. It explains the creation of chromosomes, metabolic pathways, and the features of the earliest prokaryotes. Users will find a detailed exposition of the World RNA Hypothesis in an accessible and easy-to-read style which is comprehensible for both science and non-science majors.This textbook is a critical resource for upper-level undergraduate students in Cellular Biology, specifically those studying or researching evolution, cellular chemistry, and pre-biotic chemistry, as well as non-science majors in courses on the philosophy of science or related topics. It is also useful for professionals in biochemistry, evolutionary biology, and astrobiology who wish to understand the origins of life and first cells. Science communicators could use this interdisciplinary textbook for teaching and dissemination to broader audiences as well.

  • Cryptic Enzymes and Moonlighting Proteins

    • 1 Edición
    • Helen Irving + 2 más
    • Inglés
    Cryptic Enzymes and Moonlighting Proteins, a new volume in the Foundations and Frontiers in Enzymology series, offers a thorough overview of cryptic enzymes and moonlighting proteins in signaling cascades. In early chapters, leading international contributors discuss evolutionary considerations for moonlighting proteins, moonlighting interactions in the extracellular matrix, eukaryotic moonlighting proteins, modulating, moonlighting kinases, moonlighting proteins in neurobiology signaling, metabolic enzymes moonlighting as RNA binding and regulatory proteins. Later, methods-driven chapters discuss practical aspects of identifying hidden moonlighting domains in proteins, computational approaches and bioinformatic tools for the identification of cryptic enzymes, establishing cryptic enzyme interactomes, and assessing contributions of moonlighting proteins to signal cascades.The book also explores recent advances in research and brings together an array of information across different fields to enable better targeting of these exciting proteins and their interactomes. With a clear focus on the role of moonlighting and cryptic enzymes in signal transduction, users will find examples of cryptic enzymes across species, as well as those in human healthy biology and pathogenesis.

  • Mechanical Separation Processes in the Food Industry

    Unit Operations and Processing Equipment in the Food Industry
    • 1 Edición
    • Seid Mahdi Jafari + 1 más
    • Inglés
    Mechanical Separation Processes in the Food Industry, a volume in the Unit Operations and Processing Equipment in the Food Industry series, explains the processing operations and equipment necessary for mechanical separation unit operations, including filtration, centrifugation, sieving, metal detection, sedimentation, etc. These processes and unit operations are very important in the manufacture of products such as cream, fruit juices, beverages, refining of edible oils and sugar. The book's chapters emphasize basic texts relating to experimental, theoretical, computational, and/or applications of food engineering principles and the relevant processing equipment for mechanical separation unit operations.Written by experts in the field of food engineering, and in a simple and dynamic way, this book targets industrial engineers working in the field of food processing and within food factories to make them more familiar with the particular food processing operations and equipment.

  • Kidney Development and Regeneration

    • 1 Edición
    • Volumen 163
    • Inglés
    Kidney Development and Regeneration, Volume 163 provides an up-to-date account of kidney development, congenital disease and regeneration. It has an emphasis on areas of the field that have been moving most quickly over the last few years, and that show potential for further rapid discovery. Each chapter is written by leading researchers, and their approaches range from genetics to cell biology to pharmacology to physiology to pathology to mathematical modeling. The volume is essential reading for those working on renal development, regeneration or pathology, and also those researching related aspects in similar organs.

  • Emerging Paradigms in Delivery Systems for Antitubercular Therapy

    • 1 Edición
    • Rajeev Sharma + 3 más
    • Inglés
    Emerging Paradigms in Delivery Systems for Antitubercular Therapy provides an up-to-date and thorough overview of the state-of-the-art of concepts, design, and recent advances in nanomedicines and nanobiotechnology-ba... strategies for the treatment of tuberculosis. The book enables researchers to prepare a variety of nanotechnology-based strategies, investigate their properties, and discover their uses and applications in antitubercular therapy, focusing on advanced nanomaterials that are utilized for encapsulation of nucleic acid, mRNA, DNA, and tuberculosis vaccination.This book covers all major topics that have shaped the development of nanomedicine and propelled it to its current place at the forefront of Nanotechnology based treatment innovation. It will be a welcomed resource for researchers and readers with more and more challenging therapy and biologicals with their possible modifications to be used for the effective therapy of tuberculosis.

  • Epidemiology of Cannabis

    Genotoxicity, Neurotoxicity, Epigenomics and Aging
    • 1 Edición
    • Albert Stuart Reece + 1 más
    • Inglés
    Epidemiology of Cannabis: Genotoxicity, Neurotoxicity, Epigenomics and Aging provides a novel and comprehensive exploration of five areas that have previously been associated with cannabis use, namely mental health in adults and young adults, pediatric autism, congenital anomalies, cancers, and aging. The book also explores the possibility of how these associations might be reflected in overall disease trends at the population health level. This book surveys these five areas in detail and applies cutting-edge analytical software and geospatial space–time analytical techniques to these questions. With all this information gathered into one book in an easily readable form, this book is a reference for clinicians, health science and allied health practitioners, public health and basic science researchers and drug and health regulators interested in these topics. It is also suitable for inclusion in course work and study preparation courses at both the undergraduate and postgraduate levels.

  • Advances in Agronomy

    • 1 Edición
    • Volumen 191
    • Inglés
    Advances in Agronomy, Volume 191, the latest release in this leading reference on agronomy, contains a variety of updates and highlights new advances in the field, with this volume presenting chapters on Climate-smart water technologies and strategies for a resilient forage production system, Principles and Application of Nitrogen Management in Precision Agriculture: A Review, No-Till System: a genuine Brazilian technology that meets current global demands, Nutrient management in crop production and dynamics of soil organic carbon in the Indo-Gangetic plains of South Asia, A Global Review of the Impacts of Saltwater Intrusion on Soils and Ecosystems, and more.Other chapters cover Optimizing nitrogen use efficiency in European livestock systems: From feed to plant growth, and Impact of Soil Erosion on Soil Organic Carbon Loss and Its Implications for Carbon Neutrality

  • Apobec Enzymes

    • 1 Edición
    • Volumen 713
    • Inglés
    Apobec Enzymes, Volume 713 in this series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Chapters in this new release include Fluorescent shift assay for APOBECs RNA editing, Low Error Sequencing Methods to Detect APOBEC-mediated RNA editing: Circular RNAseq and Safe-Sequencing System, "Safe-Barcode" RNAseq assay for APOBECs RNA editing, DT40 cell system to characterize somatic hypermutation, CH12 cell system to assay AID activity on class switch recombination, Purification of Enzymatically Active APOBEC Proteins from an Insect Cell Expression System, and more.Additional chapters cover Defining genome-wide mutagenic impact of APOBEC3 enzymes, APOBEC-induced mutational assay in yeast, Assays for APOBEC drug discovery, Biochemical assay for the identification of APOBECs inhibitors, An In Vitro Cytidine Deaminase Assay to Monitor APOBEC activity on DNA, Profiling rare C-to-U editing events via direct RNA sequencing, Global quantification of off-target activity by base editors, and so much more.

  • Navigating the Complexities of SARS-CoV-2 Immunobiology

    The Science Behind the COVID-19 Pandemic
    • 1 Edición
    • Volumen 213
    • Inglés
    Navigating Complexities of the SARS-CoV-2 Immunobiology: The Science behind the COVID-19 Pandemic offers a comprehensive exploration of the immune response to COVID-19. This volume brings together research and insights from leading experts to address key aspects of COVID-19 immunology, including T cell responses, cytokine storms, immune evasion strategies, and the impact on preexisting conditions. It also examines the long-term implications of the disease, such as long COVID and its intersection with autoimmunity, as well as the role of the microbiome. This compilation provides a deep understanding of the durability of immune responses post-infection and vaccination, presenting novel perspectives on therapeutic approaches and the path forward in combating this global pandemic.

  • Translational Gastroenterology

    • 1 Edición
    • Adam E.M. Eltorai + 3 más
    • Inglés
    Translational Gastroenterology covers the principles of evidence-based medicine and applies these principles to the design of translational investigations. Readers will learn important concepts, including case-control study, prospective cohort study, randomized trials, and reliability study. Medical researchers will benefit from greater confidence in their ability to initiate and execute their own investigations, avoid common pitfalls in gastroenterology, and know what is needed in collaboration. Further, this title is an indispensable tool in grant writing and funding efforts. The practical, straightforward approach helps the aspiring investigator navigate challenging considerations in study design and implementation.The book provides valuable discussions of the critical appraisal of published studies in gastroenterology, allowing the reader to learn how to evaluate the quality of such studies with respect to measuring outcomes and to make effective use of all types of evidence in patient care. In short, this practical guidebook will be of interest to every medical researcher or gastroenterologist who has ever had a good clinical idea but not the knowledge of how to test it.

  • Current Topics in Developmental Biology

    Fertilization and Activation of Development
    • 1 Edición
    • Volumen 162
    • Inglés
    Fertilization and Activation of Development, Volume 162 in the Current Topics in Developmental Biology series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.Chapters in this new release include Fertilization and the fast block to polyspermy in the African Clawed Frog, Xenopus laevis: A historical perspective, The Mammalian Egg's Zona Pellucida, Fertilization, and Fertility, Function, structure, and regulation of the broadly conserved gamete membrane fusion protein, HAP2, Gamete activation for fertilization and seed development in flowering plants, Paternal contributions to mammalian zygote, and much more.Additional sections cover Ovarian follicle formation and activation, Cytoskeletal dynamics in gamete (pro)nuclear migration across flowering plants, animals, and yeast, and Luteinizing hormone-induced changes in the structure of mammalian preovulatory follicles.

  • Atlas of Marine Invertebrate Larvae

    • 2 Edición
    • Michael J. Boyle + 2 más
    • Inglés
    Atlas of Marine Invertebrate Larvae, Second Edition covers the origins and history of marine larval science, contemporary state-of-the-art approaches to larval development and biology, and the highest-quality images and schematics showing the broadest diversity of marine larvae in the animal tree of life. This book illustrates larval body plans, the anatomy of their organ systems (muscular, sensory, digestive), including distinct ciliation patterns that facilitate swimming, and the complex metamorphic changes they undergo between different larval and growth stages. Each chapter contains in-text references that direct readers to both historical and contemporary research on the forms, functions, behaviors and biogeographical distributions of marine larvae.This book is a valuable and foundational resource for biologists across various disciplines, including biodiversity, biogeography, and developmental biology. Ecologists, taxonomists, oceanographers, and environmental scientists also benefit from the complete coverage of marine larval forms offered by this book. Additionally, the broad scope and phyletic coverage of marine biodiversity presented in this atlas is ideal for students in oceanography and marine biology, animal development, biological oceanography and invertebrate zoology.

  • Chest Blunt Trauma

    A Modern Approach to a Multidisciplinary Disease
    • 1 Edición
    • Piergiorgio Solli + 1 más
    • Inglés
    Chest Blunt Trauma: A Modern Approach to a Multidisciplinary Disease provides novel treatment ideas for cardiothoracic injuries. The book interweaves knowledge of new surgical techniques, better understanding of patho-physiologic effects of injuries, and enhanced intensive care methods to create a holistic strategy of patient support. This text is a welcome addition for any clinician or researcher seeking refreshed information on the management of trauma to the chest wall.While non-operative treatment has long been the standard of care, the book discusses the vast improvements in understanding how to treat cardiothoracic injuries. Innovative surgical techniques, instruments, post-operative care, and the multisystemic nature of this illness.

  • Gender Affirming Vaginoplasty

    • 1 Edición
    • Gennaro Selvaggi + 1 más
    • Inglés
    Gender Affirming Vaginoplasty is a novel reference of the latest research on those who present with Gender Dysphoria and desire surgery. The book describes the history of Gender Affirming Vaginoplasty (GAV), including social, legal, and ethical aspects of GAV, and explains updated Standards of Care. Users will find sections on preparation for surgery, different surgical techniques available (inclusive with the most recent developments), surgical results and complications, ways to solve complications, and finally, surgical procedures for persons who are requesting nonbinary genital surgery, and for those who are requesting reversal surgery.This is an unprecedented resource for all surgeons from various specialties already involved in gender-affirmative surgery and colleagues interested to gain state-of-the-art knowledge and experience in this field included plastic surgeons, urologists and gynecologists. Gender centers and trainees, scientists, researchers in transgender health, and organizations involved in trans health.

  • Whole Cell Biocatalysis

    Fundamentals and Applications
    • 1 Edición
    • Sergio Huerta-Ochoa + 2 más
    • Inglés
    Whole Cell Biocatalysis, a volume in the Foundations and Frontiers of Enzymology series, offers a detailed overview of the process of biocatalysis using whole cells as an alternative to enzyme biocatalysis. The book examines the potential applications and advantages of whole cell biocatalysis, including its use in the production of fine chemicals, renewable energy, and drug discovery and development. Whole cell biocatalysis for large scale production and non-conventional media are also covered. In addition, the latest methods and techniques are investigated, including cell immobilization, permeabilization, synthetic biology, computational metabolic engineering, and molecular genetics.This book provides a comprehensive summary on whole cell biocatalysis and the latest developments in this emerging field. It is an invaluable reference for researchers working across biochemistry, enzymology, biotechnology, and related fields.

  • Medicinal Plant Research in Africa

    Advances in Pharmacology and Chemistry
    • 2 Edición
    • Victor Kuete
    • Inglés
    Medicinal Plant Research in Africa, second edition is an updated and complete reference on the pharmacology of most relevant African species and their phytochemical properties. Although pharmacopoeias of most African countries are available and contain an impressive number of medicinal plants used for various therapeutic purposes, however there was no global standard book on the nature and specificity of chemicals isolated in African medicinal plants. This book has set the standard when it first published in 2013 and now is updated with novel phytochemicals belonging to diverse classes of terpenoids, phenolics, and alkaloids. The first chapter cover monoterpenes and related phytochemicals and is followed by sesquiterpenes on chapter two. Chapter tri reviews diterpenoids and chapter four provides an overview of triterpenes and steroids. Essential oils, simple phenols, phenolic acids and related esters come next in chapters five and six, respectively. The following chapters cover coumarins, flavonoids, quinones, xanthones, lignans and stilbenes. Tannins, alkaloids, and ceramides. Chapters 15 to 20 focus on specific health conditions starting with antibiotic infection, antimalarial and other antiprotozoal diseases, cytotoxic and anticancer activity, anti-inflammatory and analgesic action, antidiabetic botanicals and the applications of African plant phytochemicals on reproductive, cardiovascular, and central nervous systems conditions. The final chapter covers the market and industry updates since the first edition published. "Medicinal Plant Research in Africa, 2 Ed." provides a complete overview of the main phytochemical principles present in the African flora and their pharmaceutical use. Pharmaceutical scientists, Ethnopharmacists, botanists, and medicinal chemists will benefit from the content organization and the inclusion of the most recent methods for structural identification of phytochemicals, pharmacological techniques, and data interpretation.

  • Stress and The Brain: Evidence from Molecular Mechanisms to Interventions and Therapies

    • 1 Edición
    • Volumen 291
    • Inglés
    Stress and The Brain: Evidence from Molecular Mechanisms to Interventions and Therapies is a comprehensive exploration of how stress affects the brain at a molecular level and its broader implications for mental and neurological health. The book delves into the mechanisms by which stress triggers changes in brain function, including the activation of the hypothalamic-pituita... (HPA) axis, synaptic plasticity alterations, oxidative stress, neuroinflammation, and mitochondrial dysfunction. It examines how these molecular processes contribute to conditions such as neurodegeneration, anxiety, depression, and other stress-related disorders. Furthermore, the book provides an in-depth analysis of current therapeutic interventions, both pharmacological and behavioral, as well as natural antidotes that aim to mitigate the adverse effects of stress on the brain. By synthesizing evidence from cutting-edge research, this book offers valuable insights for scientists, clinicians, and mental health professionals seeking to understand and address the complex interplay between stress and brain health.

  • Tumor-Targeting with Stimuli-Responsive Vesicular Nanocarriers

    Basics to Emerging Applications
    • 1 Edición
    • Ankit Jain + 2 más
    • Inglés
    Tumour-Targeting with Stimuli Responsive Vesicular Nanocarriers: Basics to Emerging Applications not only acquaints scientists and science interns with the fundamental knowledge of the experimental aspects and state-of-the-art technology for vesicular carriers to equip their rational application in tumor targeting, but also provides a holistic understanding of regulatory concerns, patents, and clinical trials. In 15 chapters. this book provides basics and advances in stimuli-responsive vesicular carriers for tumor targeting based on findings outlined in highly organized tables, illustrative figures, and flow charts.With a focus on the extrapolation of bioengineering tools in the domain of vesicular carriers, stimuli-responsive features concerning tumors, drug delivery approaches, and associated challenges, it helps readers to define the major gaps in knowledge that can lead to significant scientific discoveries in therapy, diagnosis, and theragnosis of cancer.

  • The Potential of Cancer Biomarkers

    From Discovery to Clinical Application
    • 1 Edición
    • Pranav Kumar Prabhakar
    • Inglés
    The Potential of Biomarkers: From Discovery to Clinical Application addresses the challenges related to knowledge dissemination, interdisciplinary understanding, diagnostic complexity, quality assurance, patient care, research advancement, education, and professional development within the field of clinical biochemistry. The book provides a holistic solution by offering comprehensive insights and practical guidance to a diverse audience, contributing to the enhancement of healthcare and biomedical research. Each chapter explores the multifaceted landscape of biomarker research, offering a wealth of insights and expertise in genomics, proteomics, metabolomics, and more.Cancer biomarkers, the molecular signatures of cancer, hold immense promise in revolutionizing how we diagnose, treat, and personalize therapies for cancer patients. In this curated reference, esteemed contributors explore the multifaceted landscape of biomarker research, offering a wealth of insights and expertise in genomics, proteomics, metabolomics, and more.

  • Terrestrial Biomes

    Global Biome Conservation and Global Warming Impacts on Ecology and Biodiversity
    • 1 Edición
    • Germano Leão Demolin-Leite
    • Inglés
    Terrestrial Biomes: Global Biome Conservation and Global Warming Impacts on Ecology and Biodiversity explores the effects of anthropogenic activities on Earth’s terrestrial biomes, species, and climate. The book summarizes operational and potential monitoring tools to conserve or recover terrestrial biomes at a global scale. Written by international experts in ecology and biodiversity conservation, this book identifies the challenges and threats to terrestrial organisms and connects them to real cases of conservation.This is an important resource for students, professors, researchers, and governmental and non-governmental organizations active in biodiversity conservation and climate change mitigation.

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