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Elsevier

Libros en Ciencias de la Vida

  • Sweetened Concentrated Milk Products

    Science, Technology, and Engineering
    • 1 Edición
    • Juan Sebastián Ramírez-Navas
    • Inglés
    Sweetened Concentrated Milk Products: Science, Technology, and Engineering provides the most updated and comprehensive knowledge on different SCM products, delving into the production processes for each. Written by international experts, this book discusses existing information on concentrated milk and its more commercial forms, including evaporated and condensed milks. Other products detailed in this text include dulce de leches, such as sweetened caramelized goat’s milk, panelitas de leche (milk panels), and various milk-based delicacies. The book presents the definition, main characteristics, common defects, and elaboration process for each commercial form. In addition, the book includes lifetime calculation data and results of the addition of whey into milk candies. Lastly, it provides information on the quality parameters which all SCMs must meet, including experimental design and application examples in SCM research and development. This is a vital resource for researchers and practitioners in dairy science with interests and work in SCM product formulation, technology, and seeking solutions for their defects.

  • Scale-up and Chemical Process for Microbial Production of Plant-Derived Bioactive Compounds

    From Laboratory to Industry
    • 1 Edición
    • Yongjun Wei + 2 más
    • Inglés
    Many plant-derived bioactive compounds are the foundation for drugs or effective drugs to cure diseases. Usually, the bioactive compounds in plant biomass are low, and the extraction of bioactive compounds from plants is not eco-friendly, which limits their application in drugs and other industries. While the biosynthesis of some complex bioactive compounds is possible, the scale-up and chemical process technology still needs further application in commercial production of the plant-derived bioactive compounds.Scale-up and Chemical Process for Microbial Production of Plant-Derived Bioactive Compounds: From Laboratory to Industry summarizes recent commercial microbial production strategies for plant-derived bioactive compounds. This comprehensive summary will be of great interest to scientists and researchers, as well as engineers who work on the microbial production of plant-derived bioactive compounds in the industry.

  • Replacement Therapies in Adrenal Insufficiency

    • 1 Edición
    • Peter C. Hindmarsh + 1 más
    • Inglés
    Replacement Therapies in Adrenal Insufficiency provides a thorough understanding of the conditions which result in adrenal insufficiency. Never before has one source of information combined all updates on current causes and mechanisms of adrenal sufficiency to allow for quick reference and subsequent treatment decisions. Scientific data on this broad condition includes specific disease coverage of Addison’s disease, hypopituitarism, congenital adrenal hypoplasia and adrenalectomy. Practical points in diagnosis, dosing, drug interactions, replacement therapies and emergency situations are also provided as guidance for overall management.

  • Functional Foods and Chronic Disease

    Role of Sensory, Chemistry and Nutrition
    • 1 Edición
    • Michel Aliani + 1 más
    • Inglés
    Functional Foods and Chronic Disease: Role of Sensory, Chemistry and Nutrition explores the range of functional foods that are effective against a wide range of chronic diseases and addresses the impact of functional food bioactive compounds on organoleptic properties. Beginning with an introduction that details the key sensory and advanced instrumental methods essential for addressing the common problems associated with designing functional foods, the book also addresses the impact of aging and chronic diseases on sensory acuity as well as the effectiveness of functional foods in treating a wide range of chronic diseases. Sections highlight the need for acceptable functional foods for individuals suffering from a wide range of chronic diseases and contain practical recommendations for their development. Food scientists, nutritionists, dietitians, food product developers, food supplement producers, food ingredient developers, natural product scientists, herbalists, and pharmacists, as well as students studying related areas, will benefit from this important resource.

  • CRISPRized Horticulture Crops

    Genome Modified Plants and Microbes in Food and Agriculture
    • 1 Edición
    • Kamel A. Abd-Elsalam + 2 más
    • Inglés
    CRISPRized Horticultural Crops: Genome Modified Plants and Microbes in Food and Agriculture summarizes applications of CRISPR/Cas systems and its advanced variants e.g., CRISPR/Cpf1, base editing and prime editing, for precise editing of horticultural crops. The book discusses vector transformations methods, epi-genome, deep learning, synthetic biology, and precision breeding for improving yield and quality related attributes in horticultural crops. With coverage of the relevant technologies and their applications, the book also includes bioinformatics and large-scale databases and their potential application in fruits, vegetables and ornamental plants and sections on regulatory concerns related to CRISPR edited crops. Horticultural crops, including fruit, vegetable and ornamental plants are an important component of agriculture production systems and play an important role in sustaining human life.

  • Myeloid-Derived Suppressor Cells

    • 1 Edición
    • Volumen 184
    • Inglés
    Myeloid-Derived Suppressor Cells, Volume 184 in the Methods in Cell Biology series includes comprehensive protocols to assess the role of myeloid-derived suppressor cells (MDSCs), an immature, heterogenous cell population from the myeloid lineage with a potent immunosuppressive activity in a variety of diseases. This volume includes interesting protocols that address the Detection of myeloid-derived suppressor cells by flow cytometry, Determination of murine myeloid-derived suppressor cells by flow cytometry, Isolation of Myeloid-Derived Suppressor Cells (MDSC) from Endometriotic Mice Model and their Immunomodulatory Functions, Simple protocol for measuring CD11b+ GR-1+ (Ly6C+/Ly6G+) myeloid cells from a minimum volume of mouse peripheral blood, and much more.Additional chapters cover Assessment of myeloid-derived suppressor cell differentiation ex vivo, Single clonal tracking on biomimetic microtextured platforms for real-time guided migration analysis of myeloid-derived suppressor cell dissemination characteristics ex vivo, Isolation and immunosuppressive functions of myeloid-derived suppressor cell-derived exosomes, Characterization of lysosomal acid lipase in Ly6G+ and CD11c+ myeloid-derived suppressor cells, In Vitro Osteoclastogenesis Assessment using Murine Myeloid-derived Suppressor Cells, Estimating Nitric Oxide (NO) from MDSCs by Griess Method, and In vitro generation of myeloid-derived suppressor cells (MDSCs) from hematopoietic progenitor cells (HPCs).

  • Enhancement of Brain Functions Prompted by Physical Activity Vol 1

    • 1 Edición
    • Volumen 283
    • Inglés
    The goal for this special edition of Progress in Brain Research extends beyond merely probing the yet-to-be-uncovered links between physical exercise and cognitive improvement. We aim to advance our knowledge, pushing the envelope of what is currently understood. We are particularly focused on how purposefully structured physical activities, carefully chosen participant groups, and specific cognitive areas can optimize the cognitive and mental health benefits derived from physical exercise. The inaugural volume of this series introduces 3 review articles and 7 original pieces of research, encompassing both behavioral experiments and neuroimaging studies. Our focus is on experimental research that sheds light on the immediate and long-term impact of physical exercise on cognition as well as expert opinions and systematic reviews that compile current findings and suggest avenues for upcoming research.

  • Encyclopedia of Fish Physiology

    • 2 Edición
    • Sarah L. Alderman + 1 más
    • Inglés
    Encyclopedia of Fish Physiology, Second Edition is a comprehensive, introductory-level reference work that aims to unite readers in the wonders of this discipline. Chapters highlight where physiological systems and processes are conserved across vertebrate groups, which supports the use of fish as a vertebrate model for investigating fundamental problems in physiology and knowledge transfer to the medical field. Other chapters highlight unique specializations and adaptations that allow fish to survive in challenging environments, leading to a deeper appreciation of the natural world. Final sections demonstrate the consequences of perturbing physiological systems and how this knowledge can empower conservation strategies to protect fish. Much has changed in the field of fish physiology since publication of the previous, Prose award winning, edition. For example, we understand better the impacts of global climate change on the physiological systems of fish, and we have gained a deeper mechanistic understanding of physiological processes through technological advancements such as gene editing with CRISPR, whole genome sequencing, and quantitative ‘omic` approaches. The new edition greatly expands the closing thematic section focused on applying fish physiology to real world challenges with topics including ocean acidification, declining habitat quality due to human activities, and the use of zebrafish in biomedical studies on tissue regeneration, neurological disorders and cancer.

  • Polymeric Membrane Formation by Phase Inversion

    • 1 Edición
    • Naser Tavajohi + 1 más
    • Inglés
    Polymeric Membrane Formation by Phase Inversion analyzes the four main phase inversion techniques. Effective parameters in each technique are covered, along with the methodologies needed to prepare advanced membranes for specific separations in both liquid and gas phases. Roll-to-roll casting, spinning hollow fiber, and electrospinning nanofibers are presented, along with an analysis of the impact of solvent toxicity, membrane production, and the source of raw materials on the environment. The book describes a roadmap for designing different morphological characteristics for preparing specific membranes for special applications, along with the merits and disadvantages of each method. This book provides an easy, comprehensive reference for academic and industry professionals working in membrane engineering.

  • Beneficial Microbes for Sustainable Agriculture under Stress Conditions

    Functional Traits and Regulation
    • 1 Edición
    • Tongmin Sa
    • Inglés
    Beneficial Microbes for Sustainable Agriculture under Abiotic Stress: Functional Traits and Regulation highlights the potential for microbe-mediated stress phytotolerance to be improved by presenting multiple scenarios of application and results.In most research and studies, abiotic stress is applied singularly to specific plants inoculated with a bioinoculum or a microbial consortium to isolate specific plant-microbe responses. However, in reality, plants are continually exposed to a multitude of different stresses simultaneously occurring. This book presents microbial functional traits and microbe-mediated plant responses under both specific or combined stress conditions. Collectively, it provides insights into microbial functional traits and microbe-mediated plant responses in a wide range of conditions, providing foundational understanding of their potential benefits, and inspiring further research.The book also centers on specific microbial strains and groups which have been shown to effectively promote stress tolerance, and which could be utilized to boost agricultural production under stress conditions. Their potential utilization in stress affected lands not just improves crop production but could also be in line with sustainable agriculture.With the advancement of tools such as omics related technologies, emerging information on microbial functional traits and regulations on microbe-mediated phytotolerance will also allow us to develop relevant biotechnologies harnessing potentials of plant-microbe interactions under stress conditions. The information in this volume will be of interest to those working toward these next steps.

  • Modern Inference Based on Health-Related Markers

    Biomarkers and Statistical Decision Making
    • 1 Edición
    • Albert Vexler + 2 más
    • Inglés
    Modern Inference Based on Health Related Markers: Biomarkers and Statistical Decision Making provides a compendium of biomarkers based methodologies for respective health related fields and health related marker-specific biostatistical techniques. The book introduces correct and efficient testing mechanisms, including procedures based on bootstrap and permutation methods with the aim of making these techniques assessable to practical researchers. In the biostatistical aspect, it describes how to correctly state testing problems, but it also includes novel results, which have appeared in current statistical publications.In addition, the book discusses also modern applied statistical developments that consider data-driven techniques, including empirical likelihood methods and other simple and efficient methods to derive statistical tools for use in health related studies.

  • Marine Bivalve Mollusks and Emerging Pollutants

    • 1 Edición
    • Guangxu Liu
    • Inglés
    Marine Bivalve Mollusks and Emerging Pollutants: Toxicological Impacts provides the most updated and comprehensive knowledge of the toxicological impacts of a variety of emerging pollutants on marine bivalve mollusk species. In addition to synthesizing recent toxicological findings, the book also discusses toxification mechanisms, current challenges, and future research prospects. Written by international experts, this book assesses new advances in the toxicological impacts of pollutants, including microplastics, bromide flame retardants, nanomaterials, pharmaceutical residues, personal care products, pesticides, and perfluorinated compounds. In addition, it details how these can affect reproduction, embryonic development, metabolism, and immune systems of marine bivalves. Behavioral responses and neuroendocrine regulation is also discussed. Toxification mechanisms are interpreted at both physiological and molecular levels. The book concludes with current research and environmental challenges and potentials for further, future study techniques.

  • Biostimulants in Plant Protection and Performance

    • 1 Edición
    • Azamal Husen
    • Inglés
    Biostimulants in Plant Protection and Performance provides the latest research on biostimulants, a diverse class of compounds that includes substances or microorganisms that are helpful in sustainable plant growth and development. These substances accelerate plant growth, yield, and chemical composition even under unfavorable conditions, and include nitrogen-containing compounds, humic materials, some specific compounds released by microbes, plants, and animals, various seaweed extracts, bio-based nanomaterials, phosphite, silicon, and more. Additionally, the book discusses new generation products and bioproducts that are being developed for sustainable plant growth and protection, including research updates in biotechnology, nanobiotechnology, and the protective role of biostimulants. As the use of new generation biostimulants can enhance plant production systems through a significant reduction of synthetic chemicals, such as pesticides and fertilizers, and even elicit plant tolerance to various climate change-related stresses, this book is a welcomed edition to many fields of study.

  • Diagnosis and Treatment of Osteoporosis

    A Case-Based Approach
    • 1 Edición
    • Ronald C. Hamdy
    • Inglés
    **Selected for 2026 Doody's Core Titles in Endocrinology/Metabo... Disease**Diagnosis and Treatment of Osteoporosis: A Case-Based Approach is a practical guide that will be useful to a wide range of practicing and in-training clinicians, including physicians, nurse practitioners and physician assistants. With its clinical case and scenario-based approach, readers can quickly decide which clinical problem to address such as the management of osteoporosis of a particular clinical problem (Atypical femoral shaft fractures, Glucocorticoids and bone health, etc.). Each chapter is self-contained with a list of objectives at the beginning and a presentation of clinical cases that encourages self-learning to non-specialized clinical staff. This book is easily accessible to non-specialists, allowing any healthcare provider to learn how to diagnose and manage osteoporosis in the context of their practice.

  • Biochemical Immunology of Diabetes and Associated Complications

    • 1 Edición
    • Pratima Tripathi + 2 más
    • Inglés
    Biochemical Immunology of Diabetes and Associated Complications offers in-depth coverage of the association of biochemical and immunological aspects of the human body in diabetes. It discusses the suppression and modulation of the immune system and the impact of immunochemicals on the biochemical pathways in diabetes, along with associated complications. The book enumerates the exigency in knowledge about the immunomodulators as therapeutic targets to cure the syndrome. It will serve as an important reference for medical practitioners, researchers, medical students, masters and doctoral students. In addition, it could also be used as a reference for science graduates, science teachers, and researchers.

  • Diabetes. Secretos

    • 1 Edición
    • Michael T. McDermott + 1 más
    • Español
    Nuevo título enmarcado dentro de la serie “Secretos” que, al igual que otros títulos de la misma serie, presenta el popular formato de preguntas y respuestas, incluyendo también listas, tablas, perlas, ayudas para la memoria y un estilo fácil de leer, lo que hace que la consulta, la referencia y la revisión sean rápidas, fáciles y agradables. Este nuevo título contiene todas las preguntas que el lector podría llegar a plantearse sobre cualquiera de los temas relacionados con la Diabetes. Además, el manejable tamaño y la lista de los 100 Secretos Top en Diabetes ayudan al lector a conocer de primera mano los retos a los que debería afrontarse día a día. Cobertura actualizada de la gama completa de temas relacionados con la diabetes, incluida la diabetes durante el embarazo; control de la diabetes en pacientes con cáncer; control de la diabetes durante el ejercicio, los deportes y la competición; control de la diabetes en pacientes hospitalizados, y más. La obra ofrece acceso al contenido del e-book en inglés a través de la plataforma de e-book+

  • Inmunología básica

    Funciones y trastornos del sistema inmunitario
    • 7 Edición
    • Abul K. Abbas + 2 más
    • Español
    Nueva edición del texto derivado de la obra de referencia en Inmunología, "Abbas, Inmunología molecular y celular" en el que se presenta de una forma concisa y visual el nivel de información adecuado para el estudiante que se enfrenta por primera vez a la asignatura. Destaca su gran riqueza y calidad iconográfica. La inclusión de tablas, esquemas, puntos clave en negrita y preguntas de autoevaluación. En cuanto a las principales novedades cabe destacar la inclusión de contenidos nuevos y ampliados sobre pandemias, COVID-19 e inmunidad de rebaño, resistencia y susceptibilidad a COVID-19, vacunas de ARN y vacunas híbridas, inmunoterapia tumoral, respuestas inmunitarias innatas a los virus, mecanismos de tolerancia inmunológica e inmunoterapia para enfermedades autoinmunes, alérgicas y otras enfermedades inflamatorias y el cáncer. La nueva edición ofrece acceso a material adicional online en inglés a través de e-book+

  • Paraneoplastic Neurologic Disorders

    • 1 Edición
    • Volumen 200
    • Inglés
    Paraneoplastic Neurological Disorders, Volume 200 covers new, recent descriptions of autoantibodies against neuronal cell surface antigens (only partly associated with paraneoplastic disorders) and the introduction of new immuno-oncological drugs that can contribute to diseases that are pathogenetically indistinguishable from paraneoplastic syndromes. Besides investigating the pathogenetic mechanisms of these disorders, this book also explores what the introduction of new drugs used in immune checkpoint inhibitor cancer therapy are teaching us in terms of immunopathogenesis. Following sections present individual syndromes (phenotypical clinical manifestations) of the CNS, PNS, NMJ, and muscle.Finally, the book investigates the role of antibody markers that differentiate by cytoplasmic, nuclear, and neuronal cell surface reactivities. Side effects of the new immuno-oncological drugs increasingly used in cancer therapy are also covered.

  • Biosensors for Foodborne Pathogen Detection

    A Rapid Detection Approach
    • 1 Edición
    • Manoj Kumar Pal + 2 más
    • Inglés
    Biosensors for Foodborne Pathogens Detection: A Rapid Detection Approach covers rapid and accurate measurement for biosensing analysis. This book is organized in a systematic way, covering basic introduction and advanced approaches in biosensing and their use in the detection of food pathogens. This compilation includes chapters such as Methods, techniques and latest developments in the detection of foodborne pathogens; Basic principles in Biosensors and bioelectronics for the foodborne pathogens; Various bio-recognition receptors used in the biosensors; Nanomaterials and signal amplification in biosensors for foodborne pathogens; electrochemical biosensors for foodborne pathogens; Optical biosensors for foodborne pathogens, and more. This book act as a comprehensive resource for researchers or scientists working in food safety, especially in microbial food spoilage detection using biosensors.

  • Magnetic Tweezers for the Study of Protein Structure and Function

    • 1 Edición
    • Volumen 694
    • Inglés
    Magnetic Tweezers for the Study of Protein Structure and Function, Volume 694 in the Methods in Enzymology serial highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics, including Single membrane protein tethering for magnetic tweezer experiments, Membrane protein folding studies using a robust magnetic tweezer method, Magnetic tweezers in cell mechanics, and more.

  • Artificial Intelligence in Medicine

    From Ethical, Social, and Legal Perspectives
    • 1 Edición
    • Joseph JY Sung + 1 más
    • Inglés
    Artificial Intelligence in Medicine: From Ethical, Social, and Legal Perspectives provides answers on how to improve acceptance and diminish the anxiety of the use of AI-assisted medicine. Through a series of social, ethical, and legal discussions from clinicians, social scientists, ethicists, and legal experts, this important reference has coverage that includes good data custodianship and stewardship, data access, data bias, data & healthcare equity, privacy and confidentiality, algorithmic understanding, and regulatory guidance, accountability, and legal responsibility.This reference will explain to healthcare providers how AI will enhance healthcare, will introduce to scientists and researchers the ethical and social aspect of AI that needs to be addressed, and will urge policymakers and health authorities to consider the legal framework needed to implement AI technology in healthcare.

  • Handbook of Goldenberry (Physalis peruviana)

    Cultivation, Processing, Chemistry, and Functionality
    • 1 Edición
    • Mohamed Fawzy Ramadan
    • Inglés
    Handbook of Goldenberry (Physalis peruviana): Cultivation, Processing, Chemistry, and Functionality presents multidisciplinary coverage of P. peruviana and its role as in food, cosmetic, and pharmaceutical products. Broken into three sections, the book addresses the cultivation, species, and cultivars of Physalis peruviana, along with its chemistry, functionality, health-promoting properties, technologies, processing, and applications. Written for nutrition researchers, food scientists, food chemists, food technologists, nutritionists, and those studying related field, this book is a timely reference for those who wish to learn more about this functional food.

  • Nanotechnology for Abiotic Stress Tolerance and Management in Crop Plants

    • 1 Edición
    • Ramesh Namdeo Pudake + 2 más
    • Inglés
    Nanotechnology for Abiotic Stress Tolerance and Management in Crop Plants reviews the most recent literature on the role of nanomaterials in achieving sustainability in crop production in stressful environments. The book explores the adverse conditions caused by abiotic stress to crop plants and the methods by which these conditions can be potentially overcome through developments in nanoscience and nanotechnology. Abiotic stresses such as drought, salinity, temperature stress, excessive water, heavy metal stress, and UV stress are major factors which may adversely affect the growth, development, and yield of crops.While recent research for ways of overcoming the physiological and biochemical changes brought on by these stresses has focused on genetic engineering of plants, additional research continues into alternative strategies to develop stress tolerant crops, including the use of nanoscience and nanotechnology.

  • Microbes at Bio/Nano Interfaces

    • 1 Edición
    • Volumen 54
    • Inglés
    Microbes at Bio/Nano Interfaces, Volume 54 in the Advances in Virus Research series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of hot topics, including Advanced Hydrogel for Management of Bacterial Wound Infections, Biofilm Characterization: Imaging, analysis and considerations, Parasitic worm interactions with host molecular machinery, Investigation of microbes and surface carbohydrates using Atomic Force Microscopy, Interactions Between Microbial Cells and Titanium Implant Surfaces, Targeting Bacterial Polysaccharides with Antibodies and Vaccines, and much more.Other sections cover Using next generation sequencing to study host-pathogen interactions, Microbial Nano-Biosynthesis: Biomedical, Food and Environmental Applications, and Functional co-expression of LEA peptides: Providing an environment for efficient cellular recombinant protein expression.

  • Recent Developments in Nanomaterial-based Sensing of Human Pathogens

    • 1 Edición
    • Seshadri Reddy Ankireddy + 1 más
    • Inglés
    Recent Developments in Nanomaterial-based Sensing of Human Pathogens is a comprehensive book providing recent insights into nanomaterial-based sensing of human pathogens. The chapters cover diverse topics, including nanosensor analytical properties, the intersection of nanosensors and biological markers in pathogenic diseases, nanodevices in neurological infections, foodborne pathogen detection, viral and bacterial biomarkers, fungal disease diagnostics, mycoplasma-triggered inflammation, protozoan diseases, and mycoplasma clinical detection. This book serves as a valuable resource showcasing cutting-edge advancements in nanotechnology for pathogen detection, contributing to improved diagnosis and disease management across various domains.

  • Dynamic Aquaria

    Building and Restoring Ecosystems and the Biosphere
    • 4 Edición
    • Walter H. Adey
    • Inglés
    Dynamic Aquaria: Building and Restoring Ecosystems and the Biosphere, Fourth Edition demonstrates how the living systems modeling of aquatic ecosystems for ecological, biological, physiological research, and ecosystem restoration produce answers to very complex ecological questions. The book describes unique characteristics of water that have allowed carbon chemistry to flourish and evolve life over 4 billion years, along with current disruptions such as global warming, overfishing, and chemical pollution. New content in this edition includes the use of LED lighting, DNA sequencing in microcosm construction and analysis, and the expansion of the bioengineered tool Algal Turf Scrubbing (ATS) to combat global pollution problems.The book also features new information on marine calcification, research microcosms, thermogeography, and methods of water movement for minimizing plankton loss. It supports a deeper biological and ecological intelligence among the human population to better understand the processes behind environmental issues.

  • Gallstone Formation, Diagnosis, Treatment and Prevention

    • 1 Edición
    • Rajani Sharma + 2 más
    • Inglés
    Gallstone Formation, Diagnosis, Treatment, and Prevention describes the current scenario of gallstones and adopted treatment methods. It is a complete reference for researchers introducing new techniques to help prevent extreme treatments such as a cholecystectomy. This reference provides current knowledge and basic challenges of understanding gallstone formation, with all variations of composition, including complications of the treatment process. This content directs researchers to focus on gallstone mechanisms to design and develop new treatment methods. The book provides all possible factors for gallstone formation as well as preventative measures.

  • Applications of Artificial Intelligence in Healthcare and Biomedicine

    • 1 Edición
    • Abdulhamit Subasi
    • Inglés
    Applications of Artificial Intelligence in Healthcare and Biomedicine provides ​updated knowledge on the applications of artificial intelligence in medical image analysis. In 16 chapters, it presents artificial applications in Electrocardiogram (ECG), Electroencephalogram (EEG) and Electromyography (EMG), signal analysis, Computed Tomography (CT), Magnetic Resonance Imaging (MR), and Ultrasound image analysis. It equips researchers with tools for early breast cancer detection from mammograms using artificial intelligence (AI), AI models to detect lung cancer using histopathological image, and a deep learning-based approach to get a proper and faster diagnosis of the Optical Coherence Tomography (OCT) images.In addition, it presents 3D medical image analysis using 3D Convolutional Neural Networks (CNNs). Final sections cover an AI-based approach to forecast diabetes patients' hospital re-admissions. This is a valuable resource for clinicians, researchers, and healthcare professionals who are interested in learning more about the applications of Artificial Intelligence and its impact in medical/biomedical image analysis.

  • Pharmacological Advances in Central Nervous System Stimulants

    • 1 Edición
    • Volumen 99
    • Inglés
    Pharmacological Advances in Central Nervous System Stimulants, Volume 99 in the Mechanisms, Therapeutic Uses, and Abuse of Stimulants series, showcases recent pharmacological progress investigating both therapeutic (ADHD, binge-eating and narcolepsy) and abuse aspects of a number of stimulants, some of which are long-standing (amphetamines, cocaine and nicotine) while others are emerging (cathinones). Specific chapters in this new release include Transgenerational Epigenetic Inheritance of Phenotypes Associated with Parental Exposure to Drugs of Abuse, Dysregulation Of Brain Cholesterol Homeostasis by Psychostimulants, Modeling Methamphetamine Use Disorder in Mammals: Sex Differences in Behavioral Consequences and Gene Expression, and much more.Additional sections focus on Second Generation Stimulants – Pharmacological and Clinical Advances in The Treatment of ADHD And Binge-eating disorder, Pharmacology Of Stimulant – Opioid Co-Use, Role Of Age and Sex in Determining the Risk For Adverse Consequences Following Exposure To Amphetamines, Modafinil, An Atypical CNS Stimulant, Modulators Of Nicotine Reward-Related and Reinforcement-Relate... Behaviors, Methamphetamine Effects on Peripheral Immune System, Post-Translational Mechanisms in Neurotransmitter Efflux, The Many Enigmas of Nicotine, Genetic Variation in The Neuregulin-Erbb Signaling Pathway And Substance Use Disorders, Pharmacology And Neurotoxicology of Synthetic Cathinones, and more.

  • Retinal and Choroidal Vascular Diseases of the Eye

    • 1 Edición
    • Jay Chhablani
    • Inglés
    Retinal and Choroidal Vascular Diseases of the Eye explores a variety of retinal and choroidal vascular diseases, covering their pathogenesis, clinical features, and management strategies. The book begins with an outline of the basic features of retinal and choroidal vasculature before moving on to imaging techniques. Chapters then delve into specific diseases and abnormalities, as well as vascular diseases that are associated with systemic inflammatory diseases. The book then moves onto considering vascular diseases associated with system conditions before considering vascular tumors. Recent innovations and upcoming treatment options are also explored for the various diseases throughout the book.This comprehensive reference provides a deep dive into vascular diseases of the eye, and is a must-have reference for ophthalmologists, medical and surgical retina specialists, and researchers in related fields.

  • Microbial Essentialism

    An Industrial Prospective
    • 1 Edición
    • Raghvendra Pratap Singh + 4 más
    • Inglés
    Microbial Essentialism: An Industrial Prospective refers to properties specifically possessed by microbes, including the secretion of metabolites which make them unique. These microorganisms can be commercially exploited for beneficial purposes such as the production of whole microbial cells, for products for direct use, or as starting raw materials in the manufacture of other commercial products. The book reviews the newest techniques, approaches, and options in the use of microorganisms for the manufacture of industrially important products such as pharmaceuticals, industrial enzymes, chemicals, proteins, foods and beverages, and fuels. Additional sections cover fundamental principles of established and innovative industrial microbiology and biotechnology processes and products while also discussing industrial microorganisms and the technology required for large-scale cultivation and isolation of fermentation products.

  • Microbial Biotechnology for Bioenergy

    • 1 Edición
    • Naga Raju Maddela + 5 más
    • Inglés
    Microbial Biotechnology for Bioenergy presents emerging biotechnological and microbiological approaches in bioenergy and their economic, social, and environmental implications.Section 1 of this book includes an overview of bioenergy, global statistics and projections for future bioenergy development, the role of biotechnology and bioprocesses in bioenergy, feedstock sources, challenges, decarbonisation, and emerging innovations and technologies. Section 2 examines biotechnology and microbiology for bioenergy, including chapters on bioconversion of biomass energy and biological residues, utilizing organic waste, the biotechnology of biofuels including bioethanol, biodiesel, and biohydrogen, the sustainability of cellulosic ethanol energy and artificial photosynthesis, Power-to-X and integrating energy storage innovation, and microbial fuel cell sustainability. Finally, Section 3 explores policy and environmental aspects, providing a global perspective and impact projections based on present-day global statistics.Combining fundamentals and cutting-edge data, Microbial Biotechnology for Bioenergy is a valuable reference for biotechnologists, environmental engineers, and microbiologists working in bioenergy.Also included are ideas for new product development and possible improvement of existing products, as are insights into the unique nature of graphene and its types, including morphology and thickness, mechanical properties, electrical conductivity, elastic properties of 2D and 3D structures, and more.

  • Advances in Virus Research

    • 1 Edición
    • Volumen 118
    • Inglés
    Advances in Virus Research, Volume 118 highlights new advances in the field, with this new volume presenting interesting chapters on topics such as HCMV-encoded GPCRs in infection, disease, and pathogenesis, Defense signaling pathways in resistance to plant viruses: crosstalk and finger pointing, and Pathogenesis of neuroinvasive flaviviruses.

  • Advances in Food and Nutrition Research

    • 1 Edición
    • Volumen 108
    • Inglés
    Advances in Food and Nutrition Research, Volume 108 provides the latest advances on the impact of thermal processing on food flavonoids, the application of bioinformatics for studying food bioactive peptides, novel strategies for mitigating off-flavor perception, innovations in sustainable food packaging, the nutritional and safety aspects of edible insects in foods, the effect of novel food processing technologies on Bacillus cereus spores, and control of Salmonella in poultry production.

  • Translational Bioinformatics

    • 1 Edición
    • Volumen 139
    • Inglés
    Translational Bioinformatics is an emerging field in the direction of biomedical research. High throughput technologies can be applied to the generated biological data to develop the vaccine and personalized medicine. This volume consists of the chapters from different stalwart of the field covering the topics such as drug development, vector engineering, vaccine development and translational genomics. Chapters covered in this volume discuss the translational research related with cancer, Alzheimer disease and cardiovascular diseases. This volume includes the chapter describing the importance of computational resources and chemoinformatics for the translational health research. How Omics studies are helping to translate the laboratory data into the development of tools which are beneficial in the clinics have been described. How translational bioinformatics helpful in plant genomics to improve the crops have also been included in this volume. This volume has a chapter which describes the secrets of resistance development and further how these resistance are associated with human infectious diseases. This volume will be useful to the early career researcher in the development of research idea and develop their methodologies in the direction of bioinformatics and it will also give the insight to translate their findings.

  • RNA Therapeutics Part B

    • 1 Edición
    • Volumen 204
    • Inglés
    RNA Therapeutics, Part B, Volume 204 updates on a new class of medication based on RNA molecules, with chapters on a variety of topics, including RNA therapeutics for cardiovascular disorders, RNA therapeutics for kidney injury, RNA therapeutics for beta-thalassemia, RNA therapeutics for infectious diseases, RNA therapeutics for reproductive diseases, Potential of RNA and transcriptomic data to drive drug repurposing for various diseases, RNA therapeutics for glioma/glioblastoma, RNA therapeutics for regenerative medicine, Advances in the liposome-based delivery systems for RNA therapeutics in cancer, Advances in the polymeric nanoparticulate delivery systems for RNA therapeutics in cancer, and more.

  • Chitosan-Based Hybrid Nanomaterials

    • 1 Edición
    • Nisar Ali + 3 más
    • Inglés
    Chitosan-Based Hybrid Nanomaterials focuses on chitosan, an abundantly occurring biopolymer, to present possibilities for the removal of contaminants and a greener approach towards a cleaner environment – combining nanotechnology with the deployment of naturally occurring materials to remedy environmental challenges. This book fills research gaps and what is known about chitosan-based nanomaterials. Considering the importance of naturally occurring materials with the applied knowledge of nanotechnology in the field of environmental restoration, this book is an ideal resource for interested parties and career professionals.

  • Advances in Parasitology

    • 1 Edición
    • Volumen 123
    • Inglés
    Advances in Parasitology, Volume 123, the latest release in this ongoing series, includes medical studies of parasites of major influence, along with reviews of more traditional areas, such as zoology, taxonomy, and life history.

  • Haschek and Rousseaux's Handbook of Toxicologic Pathology, Volume 4: Toxicologic Pathology of Organ Systems

    • 4 Edición
    • Wanda M. Haschek + 3 más
    • Inglés
    Haschek and Rousseaux's Handbook of Toxicologic Pathology, Volume Four: Toxicologic Pathology of Organ Systems is a key reference on the integration of structure and functional changes in tissues associated with the response to pharmaceuticals, chemicals and biologics. Organ systems covered include cardiac, vascular and skeletal muscle systems and the endocrine, respiratory, reproductive, digestive and nervous systems. Completely revised with a new olfactory chapter, this new release is an essential part of the most authoritative reference on toxicologic pathology for pathologists, toxicologists, research scientists and regulators studying and making decisions on drugs, biologics, medical devices, and other chemicals, including agrochemicals and environmental contaminants.

  • Cell-based Cancer Immunotherapy

    • 1 Edición
    • Volumen 183
    • Inglés
    Cell-based Cancer Immunotherapy, Volume 183 provides the latest progress concerning research on anticancer cellular immunotherapies and their immunological, translation, or clinical aspects. Topics covered in this volume include Methods behind clinical DC vaccine products against glioblastoma, Fully closed and automated isolation of natural blood dendritic cells for cancer immunotherapy, Methods behind Oncolytic virus-based DC vaccines in cancer: towards a multiphase combined treatment strategy for Glioblastoma (GBM) patients, Identification of TCR repertoire patterns linked with anti-cancer immunotherapy, Training of epitope-TCR prediction models with healthy donor-derived cancer-specific T cells, Methods behind neoantigen predictions for anticancer vaccines, Methods behind CD137L-DC-EBV-VAX anticancer vaccine, and much more. Additional sections cover Gold Standard Assessment of Immunogenic Cell Death Induced by Photodynamic Therapy: From In Vitro to Tumor Mouse Models and Anti-Cancer Vaccination Strategies, Methods behind TCR analyses for colorectal cancer-associated TILs, The use of xCELLigence, Incucyte, and/or Cr/LDH/maker-release assays, Humanized mouse models for anti-cancer therapy, In vitro re-challenge of CAR T cells, Methods behind adoptively transferred tumor draining lymphocytes​ for anticancer immunotherapy, and A murine glioblastoma platform to test cellular therapies with the standard of care.

  • The Lentil Genome

    Genetics, Genomics and Breeding
    • 1 Edición
    • Jitendra Kumar + 2 más
    • Inglés
    The Lentil Genome: Genetics, Genomics and Breeding is a comprehensive volume on this important legume, from its economic importance to the latest in sequencing. The book includes botanical descriptions, discussion of lentil genetics, cytogenetics and breeding, molecular mapping genes and QTLs, as well as structural and functional genomics, genome sequencing, assembly, repetitive genome, gene annotation and synteny. Lentil [Lens culinaris ssp. culinaris Medikus] is among the earliest domesticates from the Near-East Fertile Crescent and plays a vital role in nutritional wellbeing and livelihood for the small-scale farmers in the dryland agricultural ecosystems of South Asia, Sub-Saharan Africa, West Asia, and North Africa. The classical plant breeding approach of selection-recombinat... has been used successfully for genetic improvement in lentil. However further genetic improvement for developing the high yielding cultivars is required knowledge of gene network underlying the complex traits. Realizing the importance of genomics enabled improvement in crop plants, the scientific community has recently placed major emphasis on whole genome sequencing in many major crops including lentil. This compilation of the latest lentil genome research serves the immediate needs of students, scientists and is needed to strengthen conventional crop improvement strategies of lentil.

  • Engineering Biology for Microbial Biosynthesis of Plant-Derived Bioactive Compounds

    • 1 Edición
    • Yongjun Wei + 2 más
    • Inglés
    Engineering Biology for Microbial Biosynthesis of Plant-Derived Bioactive Compounds will be of great interest to undergraduate and graduate students, scientists, researchers, and engineers who work on the microbial production of plant-derived bioactive compounds. As many plant-derived bioactive compounds are the foundation of effective drugs to cure diseases, it's important to understand the limits of their applications in drugs and other industries. With the development of synthetic biology and green biomanufacturing, the biosynthesis of complex bioactive compounds is possible. However, the engineering fundamentals for microbial biosynthetic of plant-derived bioactive compounds is vast.This book summarizes the engineering fundamental biotechnologies for microbial production of plant-derived bioactive compounds, allowing the content to be easily accessed. Coverage includes summaries of key achievements, identification of challenges, current approaches, tips and tricks, and helpful insights into critical bottlenecks.

  • Secondary Metabolites and Biotherapeutics

    • 1 Edición
    • Awanish Kumar + 1 más
    • Inglés
    Secondary Metabolites and Biotherapeutics presents the latest biotechnological advancements in the production of target secondary metabolites for medicinal use, including topics such as transcriptomics, nanotechnology, gene editing tools like CRISPR/CAS, secondary metabolites source and production.  Secondary metabolites derived from plants as a response to stress have always played a vital role in the pharmaceutical industry to produce medicines. However, their limited production in plants have always raised concerns for large-scale production. With the advancement of modern biotechnology, researchers around the globe are now able to engineer plants with specific chemical compositions.This book is a valuable resource to researchers in biotechnology, medical sciences, pharmaceutical biotechnology, pharmacology and plant biology.

  • Evaporation Technology in Food Processing

    Unit Operations and Processing Equipment in the Food Industry
    • 1 Edición
    • Seid Mahdi Jafari + 2 más
    • Inglés
    Evaporation Technology in Food Processing, in the Unit Operations and Processing Equipment in the Food Industry series, explains the processing operations and equipment necessary for recent invented non-thermal processing of different food products, including ozonation, plasma processing, pulsed electric fields, high pressure processing, irradiation and high frequency processing. These processes and unit operations are very important in terms of achieving favorable sensory properties and energy usage. Written by experts in the field of food engineering, this book targets industrial engineers working in the field of food processing and within food factories. The book is divided into four sections: “Evaporation basics," “Different types of evaporators,” “Application of evaporators in the food industry”, and “Design, control and efficiency of evaporators”. All chapters emphasize basic texts relating to experimental, theoretical, computational, and/or applications of food engineering principles and the relevant processing equipment to evaporation unit operations.

  • Early Vascular Aging (EVA)

    New Directions in Cardiovascular Protection
    • 2 Edición
    • Pedro Guimarães Cunha + 4 más
    • Inglés
    Early Vascular Aging (EVA): New Directions in Cardiovascular Protection, Second Edition continues to be the most comprehensive and authoritative resource on premature alterations in artery structure and function. The book presents a novel approach to the problem of cardiovascular disease, showing it in relation to great vessels disease and revealing a comprehensive approach to the problem of increased rigidity of the great vessels, its causes, and further consequences. This second edition contains completely updated content with expanded coverage of basic and translational research, systematic reviews of the most prominent literature, discussion of applicability of new evidence and more. Written by an international team of clinicians and researchers, this is a valuable resource to basic and translational scientists, clinical researchers and clinicians in the cardiovascular field interested in prevention, diagnosis and treatment of EVA.

  • A Biologist’s Guide to Artificial Intelligence

    Building the foundations of Artificial Intelligence and Machine Learning for Achieving Advancements in Life Sciences
    • 1 Edición
    • Ambreen Hamadani + 3 más
    • Inglés
    A Biologist’s Guide to Artificial Intelligence: Building the Foundations of Artificial Intelligence and Machine Learning for Achieving Advancements in Life Sciences provides an overview of the basics of Artificial Intelligence for life science biologists. In 14 chapters/sections, readers will find an introduction to Artificial Intelligence from a biologist’s perspective, including coverage of AI in precision medicine, disease detection, and drug development. The book also gives insights into the AI techniques used in biology and the applications of AI in food, and in environmental, evolutionary, agricultural, and bioinformatic sciences. Final chapters cover ethical issues surrounding AI and the impact of AI on the future.This book covers an interdisciplinary area and is therefore is an important subject matter resource and reference for researchers in biology and students pursuing their degrees in all areas of Life Sciences. It is also a useful title for the industry sector and computer scientists who would gain a better understanding of the needs and requirements of biological sciences and thus better tune the algorithms.

  • Aging

    How Aging Works, How We Reverse Aging, and Prospects for Curing Aging Diseases
    • 1 Edición
    • Michael Fossel
    • Inglés
    Aging: How Aging Works, How We Reverse Aging, and Prospects for Curing Aging Diseases explains the process of aging beyond mere entropy, exposing it as a complicated and dynamic process that undercuts maintenance and permits age-related disease. With a deeper understanding of the aging process, intervention becomes both easy to understand and clinically feasible.With a solid academic approach, this proposed book builds upon the substantial work published over the past 20 years, citing the newest data, up-to-date models based upon that data, and the implications for improved clinical intervention, including recent developments in gene and cell therapy. Coverage of age-related diseases includes neurodegenerative, cardiovascular, bone and joint, immune system, renal, pulmonary, and skin aging. Future directions of the field focus on interventions, including a summary of previous attempts to intervene in aging and age-related disease, the status of current research, and proposed biotech interventions, as well as their potential obstacles, risks, and benefits. This is the perfect reference for scientists, clinicians, and researchers interested in the translational research opportunities such as drug discovery, pharmacogenetics, and experimental therapeutics, not only summarizing where the field stands, but giving a clear and cogent view of where clinical medicine is going in the next decade.

  • Profiles of Drug Substances, Excipients, and Related Methodology

    • 1 Edición
    • Volumen 49
    • Inglés
    Profiles of Drug Substances, Excipients, and Related Methodology, Volume 49 provides timely and pertinent information on a variety of timely topics, including Physical Profiles of Drug Substances and Excipients; Analytical Profiles of Drug Substances and Excipients; ADME Profiles of Drug Substances and Excipients; Methodology Related to the Characterization of Drug Substances and Excipients; and Methods of Chemical Synthesis. In addition, it includes comprehensive profiles of five drug compounds: Deferasirox, Duvelisib, Regorafenib, Ponatinib and Avanafil. Finally, the book contains a chapter on Regulation and Standardization of Herbal Drugs: Current status, Limitation, Challenge’s, and Future Prospectives.

  • Strigolactones

    Synthesis, Application and Role in Plants
    • 1 Edición
    • Gausiya Bashri + 2 más
    • Inglés
    Strigolactones: Synthesis, Application and Role in Plants presents the current state of the science for this recently discovered class of plant hormones, offering foundational insights. The book covers the structure of natural and synthetic SLs, synthesis, transport, signaling, and their application, role in the growth and development of plants like seed germination, root growth, and stem branching plant architecture. Further, the crosstalk of SLs with other plant hormones and signaling molecules are discussed. Finally, the role of SLs in plant defense systems, particularly in biotic and abiotic stresses, heavy metals, salt, temperature, radiation, pesticide drought, and flood stress on plants.Concluding with the latest discoveries, future perspectives, and challenges in plant biology, this book will be a valuable reference for those in plant and agricultural sciences.

  • Pediatric and Adult Celiac Disease

    A Clinically Oriented Perspective
    • 1 Edición
    • Gino Roberto Corazza + 3 más
    • Inglés
    Pediatric and Adult Coeliac Disease: A Clinically Oriented Perspective provides an up-to-date, comprehensive, and critical overview of coeliac disease, its complications, and related disorders. The book covers epidemiological, pathogenetic, diagnostic, and treatment issues, including pediatric and adult cases, with a broad and international view. This is the perfect reference for researchers dedicated to advancing the field of translational coeliac disease research as well as clinicians who are diagnosing and managing coeliac disease throughout all of its various stages.

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