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Elsevier

Libros en Ciencias de la Vida

  • Neuromuscular Case Studies

    • 2 Edición
    • Tulio E. Bertorini
    • Inglés
    Ideal for neurologists and other health care professionals who treat patients with neuromuscular diseases, Neuromuscular Case Studies, 2nd Edition, presents more than 100 cases of both common and rare neuromuscular disorders. Dr. Tulio E. Bertorini provides the latest tools and strategies for diagnosis and management that minimize disability and maximize quality of life for your patients, including up-to-date coverage of numerous recent advances in the field. Using a multidisciplinary approach, this practical text contains two parts: the first includes basic aspects of anatomy, physiology, diagnostic tests, and therapeutic strategies; the second describes specific cases and their diagnosis and management.

  • Advances in Marine Biology

    • 1 Edición
    • Volumen 95
    • Inglés
    Advances in Marine Biology, Volume 95, the latest release in this serial that highlights new advances in the field, includes comprehensive chapters written by an international board of authors.

  • Revolution in the Seas

    Ending Overfishing and Building Pesco-Ecology, Sustainable Agro-Ecology of Fishing
    • 1 Edición
    • Didier Gascuel
    • Inglés
    Revolution in the Seas: Ending Overfishing and Building Pesco-ecology, Sustainable Agro-Ecology of Fishing provides an in-depth analysis of the dynamics between humans and disrupting marine ecosystems by extracting its wild animals. It highlights practical changes that can be implemented to prevent overfishing and create a new way of fishing, the pescoecology that benefits marine life, coastal communities, and human consumers alike.Written by a leader in fisheries science and conservation, this book begins by diagnosing the issue of overexploitation, showing the dynamics and consequences on living marine resources and ecosystems. It then goes on to demonstrate how recent scientific discoveries, including tropic network functionality, are changing humans’ approach to fishing sustainably. The final sections are devoted to ecological, economic, and social solutions.Revolution in the Seas is a vital resource for fisheries scientists, managers, academics and students in marine biology or fisheries studies. All stakeholders and citizens involved in building a sustainable relationship between humans and the sea will also benefit from this book’s revolutionary content.

  • Starch Industries

    Processes and Innovative Products in Food and Non-Food Uses
    • 1 Edición
    • Marney Pascoli Cereda + 1 más
    • Inglés
    Starch Industries: Processes and Innovative Products in Food and Non-Food Uses is the third volume of the "Underground Starchy Crops of South American Origin" book series. Organized in five volumes, this series brings information on the applied level of producing and using starch from a range of plants grown in tropical and subtropical areas that have South American origin. This book presents starch extraction and its food and non-food uses, using large and small industrial processes. The methods and equipment of these technologies are analyzed in detail, so that it is easy to be understood by a diverse public, increasing the visibility of the great potential of use of starchy tubers, rhizomes and roots, and improving processing options. Specifically in processing cassava, which is the only cultivation done on a commercial scale in South America, it is possible to extract starch in industries equipped with equipment, comparable to that of China, Thailand and Vietnam. This title also explores the extraction of smaller starches, such as canna starch, sweet potato and arrowroot from South China, which does not sell starch but transforms it into food paste in small extruders. Edited by a team of experts with a solid background on starch extraction research, the books are aimed at all those involved in research and development, new technological processes, quality control and legislation in the field of starch.

  • Neurotoxicity of Halogenated Organic Compounds

    • 1 Edición
    • Volumen 10
    • Inglés
    Neurotoxicity of Halogenated Organic Compounds, Volume 10 covers three groups of Halogenated Organic Compounds (Chlorinated, Brominated, and Fluorinated Compounds) that are legacy and emerging contaminants, providing background information, characteristics, physicochemical properties, environmental contamination, and human exposure. Specific chapters covered in this release include Perspective on Halogenated Organic Compounds, The Neurotoxicity of Polychlorinated Biphenyls (PCBs), Neuroendocrine Effects of Polychlorinated Biphenyls (PCBs), Mechanisms of PCB Neurotoxicity: AHR and THR Dogma meet RYR reality, Microbiome and the Neurotoxicity of Brominated Flame Retardants (BFRs), and much more. Other chapters cover Neuroendocrine Effects of Brominated Flame Retardants (BFRs), Focused on Polybrominated Diphenyl Ethers (PBDEs), Neurochemical Effects of Halogenated Organic Compounds: Possible Mode(s) of action and Structure-Activity Relationships, The Neurotoxic Effects of Perfluoroalkyl Substances (PFAS) in Animal Models and Human Cohorts, Neurochemical Mechanisms of Perfluoroalkyl Substances (PFAS) Neurotoxic Action, and Future Directions and Regulatory aspects of Halogenated Organic Compounds.

  • Encyclopedia of Toxicology, 4th edition, 9 volume set

    • 4 Edición
    • Philip Wexler
    • Inglés
    Encyclopedia of Toxicology, Fourth Edition is the most extensive compendium surveying the full scope of toxicology, including its chemical, biological and physical (e.g., radiation) perspectives. Spanning nine volumes, this new edition comprises 1150 thoroughly revised and 70 entirely new entries authored by experts in their respective fields, selected by a globally recognized board who have brought rigorous editorial skills to the project. New areas covered in this release include the bourgeoning field of computational toxicology, research applications of alternatives to animal testing, the rise in development and use of consumer products and their effects on populations, and the increasing introduction and use of pharmaceutical ingredients and their interactions. Other chapters of note cover artificial intelligence models of toxicological exposure and effects, extractables and leachable testing, climate change implications for humans, animals and the environment, screening models, -omics, tools such as sequence alignment to predict across species susceptibility, and much more.

  • Radiation Oncology and Radiotherapy Part C

    • 1 Edición
    • Volumen 180
    • Inglés
    Radiation Oncology and Radiotherapy Part C, Volume 180 in the Methods in Cell Biology series, highlights advances in the field, with this new volume presenting interesting chapters on timely topics, including Image-guided Radiation Therapy of tumors in preclinical models, Methods to preserve correct dosimetry in small animal irradiators, Monitoring TGFbeta signaling in irradiated tumors, Pipeline to characterize the TCR repertoire of irradiated tumors, Pipeline to identify tumor neoantigens exposed by radiation, Methods to assess abscopal responses in mice, Monitoring the biodistribution of radiolabeled therapeutics in mice, and more. Additional chapters cover Methods to assess radiation-induced fibrosis in mice, Methods to assess radiation-induced cardiotoxicity in mice, Histological assessment of intestinal injury by radiation, Methods to investigate CNS involvement in irradiated mice, Methods to characterize the exosomal output of irradiated cancer cells, and more.

  • Therapy Resistance in Prostate Cancer

    Mechanisms and Insights
    • 1 Edición
    • Volumen 20
    • Hisham Bahmad
    • Inglés
    Therapy Resistance in Prostate Cancer: Mechanisms and Insights, Volume 20 highlights the main mechanisms that are responsible for therapy resistance in PCa allowing researchers and clinicians to have a synopsis of current options and therapies that can be proposed to overcome resistance. Understanding the mechanisms responsible for chemotherapy resistance helps researchers all over the world delve deeper into the pathways behind this resistance and potentially discover new therapeutic targets for PCa. Prostate cancer (PCa) is among the most diagnosed cancers in men worldwide, as well as one of the most common causes of cancer-related deaths.Despite the advances in treatment, the disease remains associated with poor survival and resistance to cytotoxic and targeted therapies.

  • Strategies to Improve the Quality of Foods

    • 1 Edición
    • Volumen 1
    • José Manuel Lorenzo
    • Inglés
    Strategies to Improve the Quality of Foods, Volume One in the Developments in Food Quality and Safety series explores salt, sugar and fat reduction, while also discussing natural alternatives and nitrate and nitrate salts. Enrichment of foods with prebiotics, probiotics and pos-biotics in food development is also explored. This series is the most up-to-date resource covering trend topics such as Advances in the analysis of toxic compounds and control of food poisoning; Food fraud, traceability and authenticity; Revalorization of agrifood industry; Natural antimicrobial compounds and application to improve the preservation of food; Non-thermal processing technologies in the food industry, and more. Edited by Dr. José Manuel Lorenzo and authored by a team of global experts in the fields of Food Quality and Safety, this series provides comprehensive knowledge to food industry personals and scientists.

  • The Foraging Behavior of the Honey Bee (Apis mellifera, L.)

    • 1 Edición
    • John Purdy
    • Inglés
    The Foraging Behavior of the Honeybee (Apis mellifera, L.) provides a scholarly resource for knowledge on the regulation, communication, resource allocation, learning and characteristics of honeybee foraging behavior at the individual and colony level. Foraging, in this context, is the exploration of the environment around a honey bee hive and the collection of resources (pollen, nectar, water, etc.) by bees in the worker caste of a colony. Honeybees have the unique ability to balance conflicting and changing resource needs in rapidly changing environments, thus their characterization as “superorganisms” made up of individuals who act in the interest of the whole. This book explores the fascinating world of honey bees in their struggle to obtain food and resources in the ecosystem and environment around the hive. Written by a team of international experts on honey bee behavior and ecology, this book covers current and historical knowledge, research methods and modeling used in the field of study and includes estimates of key parameters of energy utilization, quantities of materials collected, and identifies inconsistencies or gaps in current knowledge in the field.

  • Handbook on Natural Pigments in Food and Beverages

    Industrial Applications for Improving Food Color
    • 2 Edición
    • Ralf Schweiggert
    • Inglés
    Handbook on Natural Pigments in Food and Beverages: Industrial Applications for Improving Color, Second Edition focuses on a color solution for a specific commodity, providing food scientists with a one-stop, comprehensive reference on how to improve the color of a particular food product. The book includes two new chapters that highlight the physical and biological fundamentals of color, as well as the specific use of curcumin and carthamin. Sections focus on specific industrial applications of natural colorants, with chapters covering the use of natural colorants in a variety of products. Other sections highlight technical formulation and potential health benefits of specific colorants. Various pigments which can be used to effectively color food and beverage commodities are presented with information on safety and testing throughout.

  • Hemodynamics and Immune Defense

    Discoveries in Pharmacology, Volume 3
    • 2 Edición
    • Michael J. Parnham + 2 más
    • Inglés
    Haemodynamics and Immune Defence: Discoveries in Pharmacology, Second Edition, Volume Three presents selected articles from the historic Discoveries in Pharmacology series that are enhanced with commentary from contemporary scholars who discuss the reception and importance of each chapter along with an updated bibliography on the subject and contributions from those involved in Nobel Prize winning discoveries and pioneering advancements in Pharmacology. This volume brings forth discussions on key discoveries in hemodynamics and immune defense, including chapters on penicillin by Dr. Selwyn and asthma by Dr. Brocklehurst. Academic and industry researchers in pharmacology and medicine, as well as advanced students in the area, will find this useful teaching tool and launch to new discoveries. Chapters can also be used to supplement course material in pharmacology and medical courses. It will also be of interest to those who are interested in the history of medicine.

  • Encyclopedia of Meat Sciences

    • 3 Edición
    • M. Dikeman
    • Inglés
    Encyclopedia of Meat Sciences, Third Edition, Three Volume Set is the most up-to-date reference work on topics central to agricultural and food science researchers at all levels. With over 250 outstanding articles written by world leading experts, the book offers unparalleled coverage of the science and technology of producing and harvesting animals for meat, along with tactics for preservation and processing. Clearly divided into 12 distinct sections, topics covered include all aspects of the production of animals, poultry, fish and other species commonly ‘farmed’ and/or ‘harvested’, as well as the science of meat preservation and processing and consumer issues. New to this third edition are chapters covering the core scientific advancements of recent years, including gene editing of animals, sustainability and zoonotic diseases. In addition, the book introduces a templatized chapter approach, thus providing consistency to the entire work and maximizing the clarity and accessibility of its content for the reader. Chapters, once again, include a variety of images, charts, graphs, and/or diagrams to enhance the text.

  • Atmospheric Nitrogen Deposition to Global Forests

    Spatial Variation, Impacts, and Management Implications
    • 1 Edición
    • Enzai Du + 1 más
    • Inglés
    Atmospheric Nitrogen Deposition in Global Forests: Spatial Variation, Impacts, and Management Implications provides the most comprehensive knowledge on spatial variation and ecological impacts of reactive nitrogen deposition in global forests, as well as forest management options to mitigate the negative impacts. Written and edited by international experts in the field, this book synthesizes recent research developments and insights in monitoring and modeling nitrogen deposition in global forests. The book also assesses ecological impacts of enhanced nitrogen deposition on forest structure and function and responses of forest ecosystems to decreasing nitrogen deposition in regions such as the European Union and North America. Finally, the book reviews indicators and thresholds for nitrogen saturation in global forests and analyzes remediation options to reduce impacts of excess nitrogen deposition. This is an important resource for researchers in forestry and biodiversity conservation, as well as graduate students, policymakers and others who want to understand environmental issues of reactive nitrogen deposition in global forests.

  • Plant Endophytes and Secondary Metabolites

    • 1 Edición
    • Dilfuza Egamberdieva + 2 más
    • Inglés
    Plant Endophytes and Secondary Metabolites provides the latest insights into the essential roles of these beneficial elements in plant growth, development, stress tolerance, and plant protection from soil-borne disease. The book provides a comprehensive guide, addressing the usefulness and utility of endophytes towards enhancing plant tolerance to abiotic or biotic stress. It identifies biomolecules with unique molecular architectures, novel enzymes of industrial importance, and explores the ecology and community structure of endophytes associated with host plants and their potential. In addition, the book addresses the needs of researchers and advanced level students in agriculture, plant sciences, and biochemistry, seeking to elucidate on plant and soil microbiome sustainable ecosystem services.

  • H2S in Plants

    Past, Present and Beyond
    • 1 Edición
    • Luzia Valentina Modolo + 1 más
    • Inglés
    H2S in Plants: Past, Present and Beyond presents translational insights from animal to plant application. The recent discovery of several aspects of the function of H2S and its homeostasis in plant cells was propelled by discoveries in mammalian models. Based on the practical application of those analytical methods to plant science, this book will guide readers in the identification and qualification of this gasotransmitter in plant cell function. In addition, it explores important roles in complex signaling networks together with calcium cations, nitric oxide, hydrogen peroxide and plant hormones.Presenting detailed descriptions of analytical methodologies, this book will enable the reader to determine H2S presence and understand it’s potential in improving stress resistance and crop productivity.

  • Precision Nutrition

    The Science and Promise of Personalized Nutrition and Health
    • 1 Edición
    • David Heber + 2 más
    • Inglés
    Precision Nutrition: The Science and Promise of Personalized Nutrition and Health organizes and integrates information on the diverse special areas of scientific expertise involved in Precision Nutrition in order to inform health professionals and inspire researchers to advance this field while applying the general principles into health care and medical research now. Broken into three sections, this book addresses the fundamentals of precision nutrition, applications of precision nutrition in health and disease, and the future directions of precision nutrition. Nutrition scientists, geneticists, physicians, dietitians, postdoctoral fellows, and epidemiologists seeking to understand Precision Nutrition will benefit from this timely reference..

  • Health Equity in Endocrinology, An Issue of Endocrinology and Metabolism Clinics of North America

    • 1 Edición
    • Volumen 52-4
    • Sherita Hill Golden + 1 más
    • Inglés
    In this issue of Endocrinology and Metabolism Clinics of North America, guest editors Drs. Sherita Hill Golden and Rana Malek bring their considerable expertise to the topic of Health Equity in Endocrinology. Top experts discuss health disparities present in endocrinology and metabolism care, with the goal of achieving more equitable patient care in the areas of diabetes, women’s reproduction, obesity, and more.

  • Remote Sensing in Precision Agriculture

    Transforming Scientific Advancement into Innovation
    • 1 Edición
    • Salim Lamine + 4 más
    • Inglés
    Remote Sensing in Precision Agriculture: Transforming Scientific Advancement into Innovation compiles the latest applications of remote sensing in agriculture using spaceborne, airborne and drones’ geospatial data. The book presents case studies, new algorithms and the latest methods surrounding crop sown area estimation, determining crop health status, assessment of vegetation dynamics, crop diseases identification, crop yield estimation, soil properties, drone image analysis for crop damage assessment, and other issues in precision agriculture. This book is ideal for those seeking to explore and implement remote sensing in an effective and efficient manner with its compendium of scientifically and technologically sound information.

  • Hemostasis Management of the Pediatric Surgical Patient

    • 1 Edición
    • Nina A. Guzzetta + 2 más
    • Inglés
    Hemostasis Management of the Pediatric Surgical Patient provides knowledge on the emerging area of pediatric hemostasis and its management. It discusses aspects of perioperative blood management in the pediatric population, including how to accurately estimate and monitor bleeding and determine optimal treatment regimens for bleeding in pediatric surgical patients. It also provides information on the implementation of intraoperative blood conservation strategies, goal-directed transfusion therapy, and postoperative estimation of bleeding and thrombotic risks. This book is a valuable resource to pediatric practitioners and researchers who need comprehensive information on pediatric hematology, from basic physiology to pre-, intra- and postoperative care of pediatric patients. The coagulation system of children evolves with age as evidenced by marked physiological differences in the concentration of hemostatic proteins between children of different age groups and adults. Consequently, there are distinct differences in hemostatic management between adult and pediatric patients.

  • Extraction Processes in the Food Industry

    Unit Operations and Processing Equipment in the Food Industry
    • 1 Edición
    • Seid Mahdi Jafari + 1 más
    • Inglés
    Extraction Processes in the Food Industry, a volume in the Unit Operations and Processing Equipment in the Food Industry series, explains the processing operations and equipment necessary for extraction of different food ingredients and nutraceuticals, including conventional and modern extraction techniques. These processes and unit operations are very important in the manufacture of products such as edible oils, sugars, coffee, tea, essential oils, and other products.Divided in three sections, "Different extraction equipment and technologies," "Application of extraction in the food industry," and "Design, control and efficiency of extraction systems," all chapters emphasize basic texts relating to experimental, theoretical, computational, and/or applications of food engineering principles and the relevant processing equipment for extraction unit operations.Written by food engineering experts, Extraction Processes in the Food Industry is a useful resource for industrial engineers working in the field of food processing and within food factories, providing information on particular food processing operations and equipment.

  • Modernizing Global Health Security to Prevent, Detect, and Respond

    • 1 Edición
    • Scott J.N. McNabb + 2 más
    • Inglés
    Modernizing Global Health Security to Prevent, Detect, and Respond explores—through thoughtful, thorough, and diverse scientific review and analyses—factors that have led to recent public health emergencies and offers a vision for a better protected global environment. The authors consider the history of global health security, governance, and legal structures with an eye toward novel approaches for the present and future. The book presents a vision for a more protected and safer global public health future (with the actions needed to achieve it) to prevent, detect, and respond to (re)emerging threats. Its aim is to chart a way forward with the understanding that future pandemics must and can be prevented. Major topics examined from a public health perspective include global health security; the growing concept of One Health; epidemic and pandemic prevention, detection, and response; reviews of past (e.g., Ebola, MERS-CoV, Zika, and COVID-19) public health emergencies of international concern; roles of information and communication technology; humanmade public health threats; and legal and ethical issues (e.g., viral sovereignty, trust, and transparency). Modernizing Global Health Security to Prevent, Detect, and Respond provides the academic substance and quality for researchers and practitioners to deeply understand the why of health emergencies, and most importantly—what we can and should do now to prepare.

  • Diagnostic Molecular Pathology

    A Guide to Applied Molecular Testing
    • 2 Edición
    • William B. Coleman + 1 más
    • Inglés
    Diagnostic Molecular Pathology: A Guide to Applied Molecular Testing, Second Edition assembles a group of experts to discuss the molecular basis and mechanisms of major human diseases and disease processes and how the molecular features of disease can be harnessed to develop practical molecular tests for disease detection, diagnosis and prognosis. The book explains how molecular tests are utilized in the treatment of patients in personalized medicine, highlights new technologies and approaches of applied molecular pathology, and discusses how this discovery-based research yields new and useful biomarkers and tests. As it is essential to stay up-to-date on new molecular diagnostics in this changing field, this book covers critically important areas in the practice of personalized medicine and reflects our understanding of the pathology, pathogenesis and pathophysiology of human disease.

  • Modern Methods of Drug Design and Development

    • 1 Edición
    • Volumen 690
    • Inglés
    Modern Methods of Drug Design and Development, a volume in the Methods in Enzymology series highlights new advances in the field with this new volume presenting interesting chapters on a variety of topics, including Recombinant protein purification for structural and kinetic studies, Steady-state kinetic analysis of reversible enzyme inhibitors, Steady-State Enzyme Kinetics, Analysis of enzyme kinetic data using ICEKAT, NMR techniques in drug discovery, Dynamic simulations and pre-steady state kinetics to guide drug discovery, Design and assay of substrate-product analogues for racemases and epimerases, Sensitive high throughput methods to screen for P450 inhibition: A- MI complex forming drugs, and more. Other chapters cover Sensitive high throughput methods to screen for P450 inhibition: B-Heme loss causing drugs, Discovery and development of inhibitors of acetyltransferase Eis to combat Mycobacterium tuberculosis, Crystallographic fragment screening in academic cancer drug discovery, Fast fragment- and compound-screening pipeline at the Swiss Light Source, Chemical biology, enzymology and drug discovery, PROTACs, Proximity-Induced Pharmacology (PROTACs), and much more.

  • Molecular Pharmaceutics and Nano Drug Delivery

    Fundamentals and Challenges
    • 1 Edición
    • Umesh Gupta + 1 más
    • Inglés
    Molecular Pharmaceutics and Nano Drug Delivery: Fundamentals and Challenges provides a thorough resource for both beginners and established scientists, bringing fundamental knowledge about key challenges of these carriers down to the molecular level. The book satisfies the need of availability of literature at single platform with the detailed knowledge to understand crucial aspects, such as regulatory, clinical, toxicological and the formulation requirements of these carriers. This is a valuable resource for graduates, pharmaceutical researchers and anyone working on aspects of pharmaceutics, molecular pharmaceutics and nano-drug/gene delivery. So called ‘novel drug delivery systems’ are numerous, with each having different approaches to their production, characterization and evaluation. The proper understanding of these dosage forms, as well as their critical attributes such as toxicity and regulatory requirements are aspects which researchers should know before they begin working on these carriers. This book provides this critical information.

  • Advances in Physical Organic Chemistry

    • 1 Edición
    • Volumen 57
    • Inglés
    Advances in Physical Organic Chemistry, Volume 57 presents the latest reviews of recent work in physical organic chemistry, providing a valuable source of information that is ideal not only for physical organic chemists applying their expertise to both novel and traditional problems, but also for non-specialists across diverse areas who identify a physical organic component in their approach to research. The book's hallmark is its quantitative, molecular level understanding of phenomena across a diverse range of disciplines.

  • Pharmacognosy

    Fundamentals, Applications, and Strategies
    • 2 Edición
    • Simone Badal McCreath + 1 más
    • Inglés
    Pharmacognosy: Fundamentals, Applications and Strategies, Second Edition represents a comprehensive compilation of the philosophical, scientific and technological aspects of contemporary pharmacognosy. The book examines the impact of the advanced techniques of pharmacognosy on improving the quality, safety and effectiveness of traditional medicines, and how pharmacokinetics and pharmacodynamics have a crucial role to play in discerning the relationships of active metabolites to bioavailability and function at the active sites, as well as the metabolism of plant constituents. Structured in seven parts, the book covers the foundational aspects of Pharmacognosy, the chemistry of plant metabolites, their effects, other sources of metabolites, crude drugs from animals, basic animal anatomy and physiology, technological applications and biotechnology, and the current trends in research. New to this edition is a chapter on plant metabolites and SARS-Cov-2, extensive updates on existing chapters and the development of a Laboratory Guide to support instructors execute practical activities on the laboratory setting.

  • Glycolysis

    Tissue-Specific Metabolic Regulation in Physio-pathological Conditions
    • 1 Edición
    • Rita Ferreira + 2 más
    • Inglés
    Glycolysis: Tissue-Specific Metabolic Regulation in Physio-Pathological Conditions provides an integrated overview of glycolysis, spanning basic biochemistry, patho-physiology and therapeutic applications. The book also instructs in methods available to study the involvement of the glycolytic events in healthy biology and disease pathology. It begins with an overview of fundamental glycobiology followed by chapters dedicated to glycolysis physiology in organs and systems, pathologic conditions related to glycolytic alterations, glycolysis as a therapeutic target and in drug discovery efforts, and methodological approaches to advance new glycolysis research. Disease areas considered range from cancer to heart failure, diabetes, inborn glycolytic pathway defects, hematologic malignancies, osteoporosis, neurodegenerative diseases and viral Infections. Omics and computational modeling, interactive study methods, and glycolysis flux measurement are described in detail, with step-by-step descriptions of experimental protocols, set-up and analysis.

  • Advances in Clinical Chemistry

    • 1 Edición
    • Volumen 116
    • Gregory S. Makowski
    • Inglés
    Advances in Clinical Chemistry, Volume 116, the latest release in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists.

  • Microbiome Drivers of Ecosystem Function

    • 1 Edición
    • Javid A. Parray + 2 más
    • Inglés
    Microbiome Drivers of Ecosystem Function, the latest release in the Microbiome Research in Plants and Soil series, focuses on advancements in microbial technologies towards harnessing the microbiome for improved crop productivity and health. The book provides insights into the diversity of endophytic microbiomes and their potential utility in agricultural production. As increased crop yield through chemical interventions have limit thresholds and alternative, natural, and/or integrated approaches are increasingly needed, this book serves as an ideal reference for researchers and students in the fields of agricultural biotechnology, biochemistry, environmental science, plant biology, agricultural sciences, and agricultural engineering.Microbia... inoculants provide ways in which food production efficiency can be improved. Plant growth-promoting soil organisms increase net crop uptake of soil nutrients, resulting in larger crops and higher yields of harvested food. These and other symbiotic associations between plants and microbes can ultimately be exploited for the increased food production necessary to feed the world, in addition to creating safer farming techniques that minimize ecological disruption.

  • The Biology of Ageing: From Hallmarks to Drugs

    • 1 Edición
    • Volumen 1
    • Richard Faragher
    • Inglés
    The Biology of Ageing: From Hallmarks to Drugs provides a series of reviews covering multiple aspects of the translational pipeline as interventions in the biology of ageing itself become a clinical reality. New chapters cover Cellular senescence and NAD+: what are the links?, Biomarker for ageing: potential and pitfalls, What chemists offer to ageing research, You are what you eat – or are you? Exploring dietary versus topical anti-oxidants in skin ageing, Clinical trials: A simple guide for gerontologists, Towards an ethical framework for geroscience, and more. The book explores links between known ageing mechanisms and new interventions, agents and actions at the nutraceutical-drug divide, the challenges and opportunities provided by biomarkers and chemistry- biology interface and lastly the ethical and operational challenges of clinical trials in the age of translational geroscience.

  • Bacterial Secondary Metabolites

    Synthesis and Applications in Agroecosystem
    • 1 Edición
    • Kamel A. Abd-Elsalam + 1 más
    • Inglés
    Bacterial Secondary Metabolites: Synthesis and Applications in Agroecosystem presents the structure, properties, and biotechnological applications of bacterial metabolites and their upcoming industrial, pharmaceutical, antimicrobial, and anticancer applications. Chapters cover topics such as the use of lactic acid bacteria as an antifungal and antibacterial agent, bacterial siderophores structure and potential applications, and the role of cyanobacteria metabolites in disease management, amongst others. Plant and agri-food environmental scientists and researchers, graduate, and post-graduate students in related fields will benefit from this reference book which is published as part of the Nanobiotechnology for Plant Protection series.

  • Snow Leopards

    • 2 Edición
    • Inglés
    Snow Leopards, Second Edition provides a foundational, comprehensive overview of the biology, ecology and conservation of this iconic species. This updated edition incorporates all the recent information from range-wide surveys and conservation projects, the results of technical and advances particularly in genetics, camera trapping and satellite tracking, and evaluates emerging threats. New chapters synthesize the novel scientific methods and statistical analyses used to develop density and population estimates and how they inform conservation and management estimates. Sections cover historical information, the main biogeographic patterns, evolutionary trends, conservational efforts, and cultural significance. Status and distribution are fully updated for all 12 countries where snow leopards occur. Other sections describe established and emerging threats, including human-wildlife conflict, illegal trade, infrastructure development, and climate change along with conservation solutions used to address these threats. The book concludes with a final section on global snow leopard initiatives and future potentials.

  • Advances in Virus Research

    • 1 Edición
    • Volumen 117
    • Inglés
    Advances in Virus Research, Volume 117, the latest release in a series that highlights new advances in the field, includes invaluable updates written by an international board of authors. Chapters in this new release include Pathogenesis of neuroinvasive flaviviruses, Cellular entry and egress of astroviruses, Rift Valley Fever virus entry and infection, and more.

  • Nanowired Delivery of Drugs and Antibodies for Neuroprotection in Brain Diseases with Co-Morbidity Factors Part B

    • 1 Edición
    • Volumen 172
    • Inglés
    Nanowired Delivery of Drugs and Antibodies for Neuroprotection in Brain Diseases with Co-morbidity Factors, Part B, Volume 172 in the International Review of Neurobiology series, includes chapters on Spinal cord injury induced exacerbation of Alzheimer's disease pathophysiology in the cord is reduced by topical application of nanowired cerebrolysin and antibodies to tumor necrosis factor alpha, Nanodelivery of histamine H3 receptor inverse agonist BF-2549 with clobenpropit a H3 receptor antagonist and H4 receptor agonist induced neuroprotection in spinal cord injury is potentiated by antioxidant compound H-290/51, and Neuromodulation and quality of life for patient with spasticity after spinal cord injury, and more.Other sections cover Efficacy of invasive and non-invasive methods for the treatment of Parkinson´s disease: nanodelivery and enriched environment, Co-administration of DL-3-n-butylphthalid... and neprilysin is neuroprotective in Alzheimer disease associated with brain injury, Nicotine Neurotoxicity Exacerbation following Engineered Ag and Cu (50-60 nm) nanoparticles intoxication, and Neuroprotection with nanowired delivery of antioxidant compound H-290/51 together with serotonin 5-HT3 receptor antagonist ondansetron.

  • Encyclopedia of Food Safety

    • 2 Edición
    • Geoffrey W Smithers
    • Inglés
    Encyclopedia of Food Safety, Second Edition, Four Volume Set provides an authoritative one-stop reference work covering all aspects of the field. Specific focus lies in the book's coverage of key industry developments over the last ten years, including: (i) detailed understanding of infectious agents and toxins and their route into the food chain; (ii) sophisticated detection and identification methods; (iii) effective control mechanisms, like heat treatment, refrigeration and sanitizers; (iv) education of food processors, handlers and consumers about safe food handling practices; (v) sanctioned food production, processing, storage and transport control protocols, like HACCP; and (vi) a strong policy and regulatory environment. With approximately 270 outstandingly written chapters from the world’s leading experts in food science, the book covers all aspects of food safety along the entire food chain and in one complete work, thus providing the ideal reference tool for professionals working across the multiple scientific disciplines and technologies that constitute modern food safety.

  • Tutorials in Clinical Chemistry

    • 1 Edición
    • Ibrahim A. Hashim
    • Inglés
    Tutorials in Clinical Chemistry is designed for trainee pathology residents, clinical chemists, medical students, and clinical laboratory scientists, in addition to those preparing for board and postgraduate examination. It is helpful to those in training as well as a teaching aid for mentors, faculty, and directors. The book is organized into 17 system-based chapters covering essential pathophysiology, biochemical investigation, and technical aspects of relevance to results interpretation. Tutorials in Clinical Chemistry is a must-have, didactic and essential knowledge as well as practical resource for learning and review.

  • Epigenetics in Human Disease

    • 3 Edición
    • Trygve O. Tollefsbol
    • Inglés
    Epigenetics in Human Disease, Third Edition examines the diseases and conditions on which we have advanced knowledge of epigenetic mechanisms, such as cancer, autoimmune disorders, aging, metabolic disorders, neurobiological disorders and cardiovascular disease. From molecular mechanisms and epigenetic technology to clinical translation of recent research, the nature and applications of the science is presented for those with interests ranging from the fundamental basis of epigenetics to therapeutic interventions for epigenetic-based disorders, with an emphasis throughout on understanding and application of key concepts in new research and clinical practice. Fully revised and up-to-date, this Third Edition discusses topics of current interest in epigenetic disease research, including stem cell epigenetic therapy, bioinformatic analysis of NGS data, epigenetic mechanisms of imprinting disorders, microRNA in cancer, epigenetic approaches to control obesity, epigenetics and airway disease, and epigenetics in cardiovascular disease. Further sections explore online epigenetic tools and datasets; early-life programming of epigenetics in age-related diseases; the epigenetics of addiction and suicide, and epigenetic approaches to regulating and preventing diabetes, cardiac disease, allergic disorders, Alzheimer’s disease, respiratory diseases, and many other human maladies. In addition, each chapter now includes chapter summaries, definitions, and vibrant imagery and figures to reinforce understanding, as well as step-by-step methods and disease research case studies.

  • Biophysics at the Nanoscale

    Applications of Functional Materials
    • 1 Edición
    • Adil Denizli
    • Inglés
    Biophysics at the Nanoscale: Applications of Functional Materials explores how nanomaterials and nanotechnology can be used effectively in biophysics. The book introduces the structures and functions of nanoscale-based materials from a biophysical perspective while also discussing nanotechnology opportunities for their purposeful manipulation and the integration of nanoscale-based materials with current top-notch tools and platforms to ultimately facilitate their potential applications in the areas like biomedicine and the pharmaceutical sciences. The book provides the most impactful research and current techniques and strategies. With contributions from an international group of experts in the field, the book is highly informative and is a reference point for learning key knowledge and information.

  • Peptide and Protein Drug Delivery Using Polysaccharides

    • 1 Edición
    • Aakanchha Jain + 1 más
    • Inglés
    Peptide and Protein Drug Delivery Using Polysaccharides offers an interdisciplinary discussion of polysaccharides applied in peptide and protein drug delivery. Chapters consider basic biology of different polysaccharides of current interest and their production at pilot and large-scale stages by various techniques including, but not limited to, cell and hairy root cultures. Other sections examine factors affecting polysaccharide absorption, metabolism, and excretion in nascent, encapsulated, or conjugated forms, with unique coverage of vaccine absorption, metabolism, and drug delivery. A final section considers analytical methods for detection in tissue fluids and homogenates. Accessible figures, tables, and graphical abstracts are included throughout to support understanding. Specific polysaccharides discussed for therapeutic purposes include cellulose, hyaluronic acid, heparin, carageenan, alginic acid, agar and myrrh, acacia, tragacanth, ghatti gum, chitin, chitosan, starch, glycogen and dextran.

  • Advances in Pig Welfare

    • 2 Edición
    • Irene Camerlink + 1 más
    • Inglés
    Advances in Pig Welfare, Second Edition continues its complete coverage of the field with fully updated information and analysis of current issues in the key areas of pig welfare. It is a comprehensive review covering both recent developments and persistent welfare issues. The book has been expanded with 10 new chapters addressing the most relevant and significant issues in industry with a more global perspective.The book is divided into four sections, starting with an introduction (Part 1) to major topics in pig welfare, such as pigs’ needs, including affective states and positive animal welfare. Part two provides an overview of production systems and reviews welfare hotspots and mitigation. Part three covers pig welfare management topics, such as pig-human interactions and precision livestock farming. Global perspectives on pig welfare, including economics, legislation, farmers attitudes and climate change, are covered in Part 4.Written by an international team of renowned researchers in the field, the book continues to be a useful resource for practicing vets involved in welfare assessment, welfare research scientists and students, and indeed, anyone with a professional interest in the welfare of pigs.

  • Functional Neurological Disorder, An Issue of Neurologic Clinics

    • 1 Edición
    • Volumen 41-4
    • David Perez + 1 más
    • Inglés
    In this issue of Neurologic Clinics, guest editosr Drs. David L. Perez and Sara A. Finkelstein bring their considerable expertise to the topic of Functional Neurologic Disorders. Top experts in the field cover issues such as functional movement disorder: assessment and treatment; functional cognitive disorder: diagnosis, treatment, and differentiation from secondary causes of cognitive dysfunction; functional speech and voice disorders: diagnosis and treatment; personalizing clinical care in functional neurological disorder: a biopsychosocial-info... perspective; and more.

  • Steroid Biochemistry

    • 1 Edición
    • Volumen 689
    • Inglés
    Steroid Biochemistry, Volume 688 in the Methods of Enzymology series, highlights new advances in the field, containing chapters on a variety of timely topics, including Cytochrome P450 Enzyme, Steroidogenic P450s (CYP11A1, 17A1, 21A2, 11B1, and 11B5), Steroid 17 alpha-hydroxylase/17... (Cytochrome P450 17A1), Enzymes of Estrogen Biosynthesis, Aromatase and Steroid Sulfatase, Estrogenic 17b-Hydroxysteroid Dehydrogenase, Hydroxysteroid Dehydrogenases (HSD), 3a-Hydroxyssteroid Dehydrogenase, Approaches to Measuring 3b-Hydroxysteroid Dehydrogenase Type 1, 3b-Hydroxysteroid Dehydrogenase Type 2, and much more.

  • Nanotechnological Aspects for Next-Generation Wound Management

    • 1 Edición
    • Pratima R. Solanki + 4 más
    • Inglés
    Nanotechnological Aspects for Next-generation Wound Management provides detailed, up-to-date literature on nanotechnology's role in wound management and its applications using nanoparticles, nanocomposites, carbon-based nanostructures and nanomaterials. Scaffolds, three-dimensional approaches, skin tissue engineering, and polymer-based films are discussed to treat wounds. This one-of-a-kind reference is ideal for health practitioners, clinicians and researchers who will find the book to be excellent reference material for updates on recent trends in nanotechnology for wound management.

  • Biodiversity and Bioeconomy

    Status Quo, Challenges, and Opportunities
    • 1 Edición
    • Kripal Singh + 2 más
    • Inglés
    Biodiversity and Bioeconomy: Status Quo, Challenges, and Opportuniti es comprehensively delivers the latest developments in theories of biodiversity and ecosystem functi oning and their major implicati ons for biodiversity conservati on through diversifying agriculture, forestry, and biomass producti on systems and linking these developments with sustainability of bioeconomy.This book provides basic understanding of biodiversity and bioeconomy, diff erent views of their interrelati onship, and their links with sustainable development goals. It also examines the research and practi ce of biodiversity and ecosystem functi oning in agriculture, forestry,and biomass producti on systems to achieve sustainable bioeconomy. Finally, this book examines status, challenges, and opportuniti es for biodiversity-centere... bioeconomy providing a way forward.

  • Antidiabetic Medicinal Plants

    Applications and Opportunities
    • 1 Edición
    • M. Naeem + 1 más
    • Inglés
    Antidiabetic Medicinal Plants: Applications and Opportunities presents new developments that are impacting the use of plants to address diabetic conditions. Presenting multiple perspectives on these plants, their identification, cultivation and application, this book presents the state-of-the-art with an eye toward the future. Presented in five parts, the book first provides an overview of plants with antidiabetic properties, then moves to the agricultural practices for the cultivation and production of those plants. Part Three focuses on the chemical composition and phytochemicals of the plants before then moving into a study of the physiological, biotechnological, and molecular approaches to optimizing these plants.The book concludes with insights into current and potential future medical and clinical applications, making it ideal for those seeking to understand the biology and chemistry of plants with anti-diabetic properties and their effective development and application.

  • Functional Dietary Lipids

    Food Formulation, Consumer Issues, and Innovation for Health
    • 2 Edición
    • Thomas A. B. Sanders
    • Inglés
    Functional Dietary Lipids: Food Formulation, Consumer Issues and Innovation for Health, Second Edition discusses this important component of the human diet and the ways it plays an essential functional role. As with the previous edition, this book covers the functionality and nutritional benefits of dietary fat in food in terms of formulation, manufacturing and innovation for health. It contains approximately 35% new content, including 5 new chapters as well as updated content in previous chapters. New content covers the health effects of fat-soluble compounds, the sustainability aspects of vegetable oil production; process engineering of fats to improve functionality and quality, and more. This second edition also includes updated data on regulations, including nutritional profiling, signposting, taxation and advertising restrictions, and the regulatory approval of novel sources of lipids. This book will be a useful reference for those wanting to explore human nutrition and dietary lipids as well as those involved in decision-making surrounding food formulation and manufacturing.

  • Stem Cells and Signaling Pathways

    • 1 Edición
    • Surajit Pathak + 1 más
    • Inglés
    Stem Cells and Signaling Pathways brings together chapters exploring the mechanism of stem cells and the signaling pathways. This book is a very concise and easy-to-use book. It serves as an ideal reference to guide investigators towards further valuable answers on the role of stem cells and will aid basic researchers and scientists in biomedical sciences and tissue engineering and regenerative medicine with a wide variety of interests in stem cell biology linking basic signal transduction for possible future therapies directed to treatments and different diseases.Significant information on signaling has been presented here. Sufficient knowledge has been provided on therapeutic approaches for the treatment of different degenerative disorders.

  • Neuropsychiatric Disorders and Epigenetics

    • 2 Edición
    • Jacob Peedicayil + 1 más
    • Inglés
    Neuropsychiatric Disorders and Epigenetics, Second Edition is a comprehensive reference on the epigenetic basis of common neuropsychiatric disorders. The volume is organized into chapters covering individual neuropsychiatric disorders, from addiction to anxiety and autism spectrum disorders, and is contributed by leading experts in their respective fields. The epigenetic aspects of each disorder are discussed in the context of the full range of associated epigenetic mechanisms, including DNA modification, histone post-translational modification, chromatin organization, and non-coding RNA. A particular emphasis is placed on potential epigenetic interventions when the effects of environmental stimuli on epigenetic states is particularly relevant to disease. This new edition has been fully updated to reflect recent research advances enabled by genomic technologies, as well as therapeutic interventions for previously unmanageable disorders. Several new chapters have been added on disorders or approaches not considered in the earlier edition, including epigenetics and anxiety disorders, epigenetics and neuroimaging in neuropsychiatric disorders, genome-wide approaches to epigenetic research, and the epigenetics of spinal muscular atrophy.

  • Treatment-Resistant Depression Part B

    • 1 Edición
    • Volumen 281
    • Inglés
    Treatment-Resistant Depression, Part B, Volume 281 in the Progress in Brain Research series, highlights new advances in the field, with this new volume presenting interesting chapters on highly relevant topics such as Treatment Resistant Depression in Children and Adolescents, Treatment Resistant Depression in Elderly, Brain Stimulation for Treatment Resistant Depression, Electroconvulsive Therapy for Treatment Resistant Depression, Psychological aspects and Psychotherapy for Treatment Resistant Depression, Psychiatric Rehabilitation and Cognitive Deficit for Treatment-Resistant Depression, Insomnia and Treatment Resistant Depression, and Tinnitus and Treatment Resistant Depression.

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