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Elsevier

Libros en Ciencias de la Vida

  • Pediatric Head and Neck Imaging, An Issue of Neuroimaging Clinics of North America

    • 1 Edición
    • Volumen 33-4
    • William T. O'Brien Sr.
    • Inglés
    In this issue of Neuroimaging Clinics, guest editor Dr. William T. O'Brien, Sr., brings his considerable expertise to the topic of Pediatric Head and Neck Imaging. The differential diagnosis of neck masses in pediatric patients differs compared to masses that arise in adults. In this issue, top experts in the field discuss imaging of hearing loss, sinus infections, neck masses, and congenital lesions, and more.

  • Advances in Stem Cells and their Niches

    • 1 Edición
    • Volumen 7
    • Susie Nilsson
    • Inglés
    Advances in Stem Cells and their Niches, Volume Seven highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.

  • Phage Therapy - Part B

    • 1 Edición
    • Volumen 201
    • Inglés
    Phage Therapy - Part B, Volume 201 covers bacteriophage and their isolation, screening, synthetic phage, diagnostics, directed evolution, host interaction, and more. The book's aim is to highlight a number of aspects of phage in a way that can help students, researchers, clinicians, entrepreneurs and stakeholders perform research. Sections cover Phages for the treatment of Pseudomonas aeruginosa infection, Phage for the treatment of Vibrio cholerae infection, Phages for the treatment of Mycobacterium species, Phage therapy for gut microbiome, Phages as delivery vehicles, Phage display, Unlocking the potential of Phages: Innovative Approaches to harnessing Bacteriophages as Diagnostic Tools for Human Diseases, and more. Other sections explore Phage display and human disease detection, Bacteriophage as Cargo and its application in nanomedicine, Phage for drug delivery vehicles, Genome editing for phage design and uses for therapeutic applications, Phage for cancer therapy, and Phage for regenerative medicine and cosmetics.

  • Chromatin Readers in Health and Disease

    • 1 Edición
    • Volumen 35
    • Olivier Binda
    • Inglés
    Chromatin Readers in Health and Disease, Volume 35, a new release in the Translational Epigenetics series, gathers and makes actionable our current understanding of how chromatin readers regulate access to genetic information, and how their aberrant regulation can contribute to human pathologies. Chromatin readers discussed include 14-3-3 Dinshaw, ADD, Ankyrin, BAH, BET, BIR, BRCT, bromodomains and Kac readers, chromodomains and chromobarrel readers, citrullination readers, macrodomains and poly-ADP-ribose readers, MBT, PHD and double PHD, PWWP, SUMO (H4K12) readers, Tudor and TTD, UDR and ubiquitin, WD40, YEATS (crotonyl reader), MBD, SRA, and Methyl-RNA readers.In the book, more than a dozen leaders in the field examine a range of protein readers, their relationship to human disease, and the early therapeutics that act as chromatin signaling factors to treat cancers and Huntington's disease, among other disorders.

  • Chromatin Remodeling Complexes and Transcriptional Coregulators

    • 1 Edición
    • Volumen 53
    • Inglés
    Chromatin Remodeling Complexes and Transcriptional Coregulators, Volume 53, the latest release in The Enzymes series highlights new advances in the field, with interesting new chapters that cover Perspectives on Chromatin Remodeling, The functions of ISWI-type remodelers in yeast, Conserved mechanisms of NuRD function in hematopoietic gene expression, The SIN3 complex as a metabolic epigenetic regulator, Soft repression and chromatin modification by conserved transcriptional corepressors, The NPAC-LSD2 complex in nucleosome demethylation, Role of intrinsically disordered domains in transcriptional regulation, and Regulation of the Recovery of Cancer from Therapy Exposure by Noncoding RNAs.

  • Medical Image Analysis

    • 1 Edición
    • Alejandro Frangi + 2 más
    • Inglés
    Medical imaging is increasingly at the base of many breakthroughs in biomedical sciences, becoming a fundamental enabling technology of biomedical scientific progress. Medical Image Analysis presents practical knowledge on medical image computing and analysis and is written by top educators and experts in the field. This text is a modern, practical, broad, and self-contained reference that conveys a mix of essential methodological concepts within different medical domains, reflecting the nature of the discipline today, making it suitable as a course text and a self-learning resource.

  • Circulating Tumor Cells, From Biotech Innovation to Clinical Utility Part A

    • 1 Edición
    • Volumen 381
    • Inglés
    "Circulating Tumor Cells, from biotech innovation to clinical utility" provides an overview of the most recent technological and clinical advances with regards to the study of circulating tumor cells (CTCs) in solid tumors. The volumes cover studies on CTCs in breast, prostate, colorectal and lung cancer, with a focus on clinical utility, and also include methodological and biological topics such as CTC culture, multi-omic characterization of CTCs, atypical CTC populations and interaction between CTCs and immunity.

  • Fungal Secondary Metabolites

    Synthesis and Applications in Agroecosystem
    • 1 Edición
    • Heba I. Mohamed + 1 más
    • Inglés
    Fungal Secondary Metabolites: Synthesis and Applications in Agroecosystem presents the properties and biotechnological applications of fungal metabolites and their industrial, pharmaceutical, antimicrobial, and anticancer applications.Chapter... cover topics including the role of fungal metabolites in the management of biotic or abiotic stress, microbial alkaloids and their pharmaceutical and agricultural applications, and fungal metabolites as novel plant pathogen antagonists. In order to develop novel bioactive compounds, researchers must understand the agricultural applications of fungal metabolites. This book provides expert insights from around the globe highlighting the latest understanding and future prospects for their use.Plant and agri-food environmental scientists, researchers, graduate, and post-graduate students in related fields will find value in this reference book which is published as part of the Nanobiotechnology for Plant Protection series.

  • Adenosine A2A Receptor Antagonists

    • 1 Edición
    • Volumen 170
    • Inglés
    Adenosine A2A Receptor Antagonists, Volume 170 in the International Review of Neurobiology series highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including A2A Adenosine Receptor Agonists, Antagonists, Inverse Agonists and Partial Agonist, Chemistry – agonists, antagonists, partial agonists, inverse agonists, Functional roles of adenosine receptors – biochemistry and neuronal plasticity, A2A and Depression, A2AR and glial function, The adenosine A2A receptor in the basal ganglia: expression in health and disease, heteromerization, functional selectivity and signaling, How and why A2a receptor become to be a therapeutic target in Parkinson’s disease therapy, and much more.

  • Crystallography of Protein Dynamics

    • 1 Edición
    • Volumen 688
    • Inglés
    Crystallography of Protein Dynamics, Volume 688, the latest release in this important series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.

  • Inoculating Cities

    Case Studies of the Urban Response to the COVID-19 Pandemic
    • 1 Edición
    • Rebecca Katz + 1 más
    • Inglés
    Inoculating Cities: Case Studies of the Urban Response of the COVID-19 Pandemic uses detailed case studies to document and describe how cities located in high, middle and low-income countries responded to the COVID-19 pandemic. City governments and municipal authorities exist and operate in extremely varied contexts (i.e., socioeconomic, demographic, legal and governance, etc.) and intentionally documenting the experiences in these different contexts provides guidance to decision-makers for future preparedness and response activities. This volume highlights the innovative solutions throughout the pandemic as described by the people who designed and implemented pandemic response efforts in their cities. In addition, it identifies successful models that can be adopted in the future by city leaders around the world.

  • Phage Therapy - Part A

    • 1 Edición
    • Volumen 200
    • Inglés
    Phage Therapy - Part A, Volume 200 is an informative text on phage and their use for treatment in bacterial infections. The book highlights a number of aspects of the phage in a way that can help students, researchers, clinicians, entrepreneurs and stakeholders perform their research with great interest. Chapters in this new release cover An introduction to bacteriophage and their therapeutic applications, Isolation, screening and characterization of phage, Synthetic phage and their application in phage therapy, Phage engineering for development of diagnostic tools, Phage design and directed evolution to evolve phage for therapy, and more. Additional sections cover Host-phage interactions and modelling for therapy, Phage and phage cocktails formulations, Phage for treatment of Escherichia coli infection, Phage for treatment of Klebsiella pneumoniae infection, Phage for treatment of Salmonella spp infection, Phage for treatment of Staphylococcus aureus infection, and Phages for treatment of Acinetobacter baumannii infection.

  • Hydrogels for Tissue Engineering and Regenerative Medicine

    From Fundamentals to Applications
    • 1 Edición
    • J. Miguel Oliveira + 2 más
    • Inglés
    Hydrogels for Tissue Engineering and Regenerative Medicine: From Fundaments to Applications provides the reader with a comprehensive, concise and thoroughly up-to-date resource on the different types of hydrogels in tissue engineering and regenerative medicine. The book is divided into three main sections that describe biological activities and the structural and physicochemical properties of hydrogels, along with a wide range of applications, including their combination with emerging technologies. Written by a diverse range of international academics for professionals, researchers, undergraduate and graduate students, this groundbreaking publication fills a gap in literature needed in the tissue engineering and regenerative medicine field.

  • Nanotechnology and Nanomaterials in the Agri-Food Industries

    Smart Nanoarchitectures, Technologies, Challenges, and Applications
    • 1 Edición
    • Pardeep Singh + 4 más
    • Inglés
    Nanotechnology and Nanomaterials in the Agri-Food Industries: Smart Nanoarchitectures, Technologies, Challenges, and Applications brings together the latest advances in the utilization of advances nanotechnology, nanoarchitectures, and nanomaterials in the agricultural and food sectors. The book begins by discussing recent trends towards sustainable synthesis and application, covering green nanomaterials and biodegradable nanomaterials and composites. Subsequent chapters focus on key application areas of engineered nanomaterials in both agriculture and food processing, such as crop production and protection, delivery vehicles, detection of contaminants, nanobionic and genetic engineering in plants, active food packaging and preservation, enhanced food formulations and nutrients, nanoscale additives for freshness, and nanosensors. This is followed by a section that addresses key challenges relating to the application of nanostructures and nanodevices in these sectors, including global market considerations, health and environmental concerns, and intellectual property and socio-economic issues. Finally, policy implications and future perspective for the field are reviewed in detail.

  • Nutrición comunitaria

    • 4 Edición
    • Javier Aranceta Bartrina
    • Español
    Nutrición comunitaria es el texto en castellano referente en la disciplina con casi 30 años de historia, dirigido por el Dr. Javier Aranceta, un reconocido experto en la aplicación de la nutrición comunitaria tanto a nivel local como en los países latinoamericanos. Está dirigido tanto a estudiantes de Nutrición como Medicina y otros grados de Ciencias de la Salud. La nueva edición sigue la misma filosofía de las anteriores, es decir presentar de forma clara y de fácil comprensión todos los aspectos relevantes en la disciplina. Esta edición incorpora 9 nuevos capítulos. Especial atención merecen los correspondientes al papel de la microbiota y el de las 7 “S” de la Agenda de 2030.

  • Viral Diseases of Field and Horticultural Crops

    • 1 Edición
    • L. P. Awasthi
    • Inglés
    Viral Diseases of Field and Horticultural Crops details the fundamental and applied aspects of the viral diseases of field and horticultural crops. The book opens with a historical introduction to plant virology, important plant virologists, and landmarks. It continues with systematic coverage of viral diseases, their economic significance, disease symptoms, host range, mode of transmission, diagnostic techniques, geographic distribution, epidemiology, yield losses, and control and management of the disease. Contributions from an international group of virologists with a wide range of academic, research, professional, and specialized backgrounds in plant virology makes Viral Diseases of Field and Horticultural Crops a comprehensive and must-have resource for those engaged in the study and research of plant virology, microbiology, and plant pathology particularly viral diseases and their impact on field and horticultural crops.

  • Advances in Food and Nutrition Research

    • 1 Edición
    • Volumen 106
    • Fidel Toldra
    • Inglés
    Advances in Food and Nutrition Research, Volume 107 provides the latest advances on emerging bioactive compounds with putative health benefits and their controlled release and application in foods and nutraceuticals, as well as information on food technologies, including 3D printing, safety of raw materials, and viruses in foods. Chapters in this new release cover Tackling food allergens - the role of food processing on proteins’ allergenicity, Plant bioactive peptides for cardiovascular disease prevention, Caffeine and sport, Nanostructured steady-state nanocarriers for nutrients preservation and delivery, Flavor perception and health benefits of tea, Next Generation Plant-based Meat Alternatives: Sources, manufacturing and consumer acceptance, and more. Other sections cover Bioprotective cultures and bacteriocins as food preservatives and Raman Spectroscopy: principles and recent applications in Food Safety.

  • Polysaccharide Hydrogels for Drug Delivery and Regenerative Medicine

    • 1 Edición
    • Tapan Kumar Giri + 2 más
    • Inglés
    Polysaccharide Hydrogels for Drug Delivery and Regenerative Medicine is an archival reference for researchers, students and scientists working on hydrogels based on microbial and animal sources. The book contains Information regarding their synthesis, characterization, and applications in the field of drug delivery and regenerative medicine. Each chapter addresses a separate polysaccharide hydrogel and its suitability in drug delivery and/or regenerative medicine. This is a novel resource that brings together a panel of highly accomplished experts in the field of natural polysaccharides to discuss basic causes and specific problems related to drug delivery and regenerative medicine.

  • Autophagy Processes and Mechanisms

    • 1 Edición
    • Rohan Dhiman + 1 más
    • Inglés
    Autophagy Processes and Mechanisms details the process of autophagy and its significance in diseases and aging. It provides insights into autophagy mechanisms and processes to broaden our understanding. By collecting recent progress on several aspects of the autophagy process, it provides a more integrative perspective and serves as a resource that can influence future research initiatives in the field. This new book is appropriate for basic and applied researchers in cell biology, biologists and those working in the pharmaceutical sciences.

  • Pharmaceutics

    Basic Principles and Application to Pharmacy Practice
    • 2 Edición
    • Alekha Dash + 1 más
    • Inglés
    Pharmaceutics: Basic Principles and Application to Pharmacy Practice, Second Edition is a valuable textbook covering the role and application of pharmaceutics within pharmacy practice. This updated resource is geared toward meeting and incorporating the current curricular guidelines on pharmaceutics and laboratory skills mandated by the American Council for Pharmacy Education. It includes a number of student-friendly features, including chapter objectives and summaries, practical examples, case studies, numerous images and key-concept text boxes. Two new chapters are included, as well as a new end of chapter section covering "critical reflections and practice applications". Divided into three sections – Physical Principles and Properties of Pharmaceutics; Practical Aspects of Pharmaceutics; and Biological Applications of Pharmaceutics – this new edition covers all aspects of pharmaceutics and providing a single and compelling source for students.

  • Biological Invasions and Global Insect Decline

    • 1 Edición
    • Jonatan Rodríguez + 2 más
    • Inglés
    Biological Invasions and Global Insect Decline offers the most updated knowledge on how invasive alien species affect insect diversity worldwide. The book provides ongoing research and the most relevant information, covering the main aspects of the impact of biological invasions as well as future insights on mitigation and consequences. It discusses how the introduction of all kinds of organisms, from bacteria and plants to vertebrates, affect current declines in insect diversity. The latter portion of the book delves into existent and future monitoring and management programs, including citizen science and regenerative ecology as socio-ecological solutions to combat these threats. Written and edited by international experts on invasion ecology and insect conservation, this book explores the role of global change and the introduction of invasive species in altering the structure of habitats and how this induces a global insect decline. This will be a valuable resource for entomologists, invasion biologists and other researchers in biodiversity conservation, as well as practitioners and stakeholders concerned about problematic invasive alien species and insect population decline.

  • Artificial Intelligence in Clinical Practice

    How AI Technologies Impact Medical Research and Clinics
    • 1 Edición
    • Chayakrit Krittanawong
    • Inglés
    Artificial Intelligence in Clinical Practice: How AI Technologies Impact Medical Research and Clinics compiles current research on Artificial Intelligence within medical subspecialties, helping practitioners with diagnosis, clinical decision-making, disease prediction, prevention, and the facilitation of precision medicine. The book defines the basic concepts of big data and AI in medicine and highlights current applications, challenges, ethical issues, and biases. Each chapter discusses AI applied to a specific medical subspecialty, including primary care, preventive medicine, general internal medicine, radiology, pathology, infectious disease, gastroenterology, cardiology, hematology, oncology, dermatology, ophthalmology, mental health, neurology, pulmonary, critical care, rheumatology, surgery, and OB-GYN. This is a valuable resource for clinicians, students, researchers and members of medical and biomedical fields who are interested in learning more about artificial intelligence technologies and their applications in medicine.

  • Neurophysiology of Silence Part B: Theory and Review

    • 1 Edición
    • Volumen 280
    • Inglés
    Progress in Brain Research serial highlights new advances in the field with this new volume presenting interesting chapters. Each chapter is written by an international board of authors

  • Synthesis of 5-Membered Heterocycles

    Role of DMF as Solvent, Reagent, Catalyst, and Stabilizer
    • 1 Edición
    • Navjeet Kaur
    • Inglés
    Synthesis of Five-Membered Heterocycles: Role of DMF as Solvent, Reagent, Catalyst, and Stabilizer helps readers quickly assess possible synthetic approaches. The book's audience, researchers, academic professionals and synthetic chemists both in industry and academia will find detailed information about the synthesis of five-membered heterocyclic compounds using dimethylformamide. Over the years, heterocyclic compounds, especially five-membered, have drawn more attention of pharmaceutical community because of their therapeutic value. The formation of heterocyclic compounds has turned out to be the keystone of synthetic organic chemistry. Dimethylformamide has played an important role in organic synthesis for a long time, and it is frequently utilized as a common solvent for chemical reactions and broadly used in industry as a reagent. It is a unique chemical and can play three other roles in organic chemistry, i.e., as stabilizer, reagent and catalyst. Due to its structure, DMF can participate in several reactions as a versatile building block for several units.

  • Hormone Receptors: Structures and Functions

    • 1 Edición
    • Volumen 123
    • Inglés
    Hormone Receptors: Structures and Functions, Volume 123 in the Vitamins and Hormones series, highlights new advances in the field with this new volume presenting interesting chapters written by an international board of authors.

  • Circadian System

    • 1 Edición
    • Volumen 137
    • Rossen Donev
    • Inglés
    Circadian System, Volume 137 in the Advances in Protein Chemistry and Structural Biology series, highlights new advances in the field, with this new volume presenting interesting chapters that comprehensively cover Circadian Systems Genes and Their Importance for Human Health, Single nucleotide polymorphisms (SNPs) in circadian genes: Impact on Gene Function and Phenotype, Relationship between circadian rhythm and diseases: sex hormones impact, Advances in circadian clock regulation of reproduction, Disruption of the clock gene expression in central and peripheral circadian oscillators by maternal overnutrition in the Oryctolagus cuniculus, COVID-19 disease management in aspect of Circadian system, and more. Other sections cover Molecular Characterization of Circadian Gene Expression and Its Correlation with Survival Percentage in Colorectal Cancer Patients, Identifying circadian gene signature that estimates overall survival from colon adenocarcinoma, The role of environmental signals in the expression of rhythmic cardiac proteins and their influence on cardiac pathologies, and much more.

  • Breeding Disease-Resistant Horticultural Crops

    • 1 Edición
    • Paul W. Bosland + 1 más
    • Inglés
    Breeding Disease-Resistant Horticultural Crops is a complete and comprehensive resource for understanding the concept of breeding disease resistant crops, especially horticultural crops. Breeders of horticultural crops face distinct challenges that are different from agronomy/row crops, and these crops do not benefit from the vast body of literature available for agronomic crops. This book covers the basic theories that underpin breeding for disease resistance and features extensive real-world examples. Both classical and biotechnical breeding methods are covered, with an emphasis on how these methods are adapted for horticultural species. Presented in a logical flow for the reader, this book addresses historical perspectives and context as it relates to breeding for disease resistance. It highlights treatments of resistance in the context of the phenotype, the genotype, the pathogen, the environment interaction, sources of resistance, and the deployment of resistance to obtain a durable resistance.

  • Computer-Aided Applications in Pharmaceutical Technology

    Delivery Systems, Dosage Forms, and Pharmaceutical Unit Operations
    • 2 Edición
    • Jelena Duris
    • Inglés
    Computer-Aided Applications in Pharmaceutical Technology: Delivery Systems, Dosage Forms, and Pharmaceutical Unit Operations, Second Edition covers the fundamentals of experimental design application and interpretation in pharmaceutical technology, chemometric methods with an emphasis on their applications in process control, neural computing, data science, computer-aided biopharmaceutical characterization, as well as the application of computational fluid dynamics in pharmaceutical technology. Completely updated, the book introduces the theory and practice of computational tools through new case studies. Chapters cover Quality by Design in pharmaceutical development, overview data mining methodologies, present computer-aided formulation development, cover experimental design applications, and much more.

  • Resident Stem Cells and Regenerative Therapy

    Sources and Clinical Applications
    • 2 Edición
    • Regina Coeli dos Santos Goldenberg + 1 más
    • Inglés
    Resident Stem Cells and Regenerative Therapy: Sources and Clinical Applications, Second Edition presents the main findings to date and the important factors to be considered when contemplating resident stem cells in regenerative therapies. Chapters on cardiac, brain, neural, liver, kidney, skeletal muscle, bone, pancreatic, skin and lung resident stem cells will assist in defining the level of success that has been achieved and the direction for the road ahead. With contributions from leading laboratories, open questions related to resident stem cells and regenerative therapies will also be presented for debate. In the last several decades, stem cells have greatly impacted the scientific and lay communities, providing huge advances in the treatment of devastating human diseases, including myocardial infarction, diabetes, muscular dystrophy, cystic fibrosis, cirrhosis, and osteoporosis. Alongside debates of induced pluripotent stem cells and embryonic stem cells has been the discovery of adult stem cells in many different tissues. While these organ resident or progenitor stem cells offer prospects to contribute to tissue regeneration, they also present challenges because of the complexity of organ structures.

  • Applications of Seaweeds in Food and Nutrition

    • 1 Edición
    • Daniel Ingo Hefft + 1 más
    • Inglés
    Applications of Seaweeds in Food and Nutrition provides an overview on the cultural, biological and engineering dimensions relating to seaweed as a food. With the need for sustainable and healthy foods growing, this comprehensive resource explores how seaweeds can deliver not only nutritional benefits, but also antiviral and antibacterial properties as a food additive and within food processing and manufacturing. Recent developments show that the use of seaweed extracts as a compound can prevent browning. It use in other areas such as a thickening and gelling agents in foods and cosmetics is also encouraging. There are hundreds of different varieties of seaweed known to mankind, yet very little literature is available on the processing of these "crops." This book provides these valuable and practical insights.

  • Handbook of Current and Novel Protocols for the Treatment of Infertility

    • 1 Edición
    • Michael H. Dahan + 3 más
    • Inglés
    The field of Assisted Reproductive Technology (ART) is rapidly evolving and stimulation protocols, fertility strategies and aspects of infertility treatments are constantly being updated as advances and new discoveries are made.Handbook of Current and Novel Protocols for the Treatment of Infertility is a valuable resource of well-organized, comprehensive scientific data with practical guides and step-by-step protocols for infertility management. Written by world-wide experts, this book discusses different practice patterns and approaches used internationally and presents innovative topics including preimplantation genetic testing, time lapse imaging and the role of artificial intelligence in ART.This book provides up-to-date, evidence-based guidance on daily practice and is an important resource for infertility providers, including trainees or experienced clinicians, embryologist, and is geared for both specialist in reproductive medicine and gynecologists interested in increasing their knowledge in the field of reproductive endocrinology and intertility.

  • Active Learning for Digital Transformation in Healthcare Education, Training and Research

    • 1 Edición
    • Miltiadis Lytras + 1 más
    • Inglés
    Active Learning for Digital Transformation in Healthcare Education, Training and Research discusses the potential of advanced training of health professionals as a contributing factor to improve treatment outcomes. By reading this book, professionals who deal with patients with low health literacy will be prepared to promote better access to digital tools, understand the habits of users of health services, and empower engagement. The book contains a set of techniques and instruments associated with health literacy, communication skills and personal development that will enable their application in good daily practices and assist healthcare professionals to promote digital transformation to patients. This is a valuable resource for researchers, graduate students and healthcare professionals who are interested in learning more about how they can be an effective agent of change in healthcare.

  • Intelligence-Based Cardiology and Cardiac Surgery

    Artificial Intelligence and Human Cognition in Cardiovascular Medicine
    • 1 Edición
    • Anthony C. Chang + 4 más
    • Inglés
    Intelligence-Based Cardiology and Cardiac Surgery: Artificial Intelligence and Human Cognition in Cardiovascular Medicine provides an especially timely multidisciplinary and comprehensive survey of artificial intelligence concepts and methodologies. It includes real-life applications in adult and pediatric cardiovascular medicine, spanning the life span from fetus to adult. Led by a senior cardiologist–data scientist and supported by renowned data scientists and cardiac clinicians with an ardent passion for artificial intelligence in cardiovascular medicine, the book provides a clinical interface between the medical and data science domains that is symmetric and realistic.The content consists of basic concepts and applications of artificial intelligence and human cognition in cardiology and cardiac surgery. This portfolio ranges from big data to machine and deep learning, as well as cognitive computing and natural language processing in cardiac disease states such as heart failure, hypertension, and pediatric cardiac care. Artificial intelligence tools are described from the intensive care unit setting to other venues, such as the outpatient clinic, catheterization laboratory, and operating room. Future applications in related areas, such as large language models, extended reality, and digital twins, are also discussed. The book encompasses more than 50 chapters written by cardiologists or cardiac surgeons. Each chapter provides sections on the current state of the art and future directions and concludes with major takeaways. A robust compendium of practical resources, such as a comprehensive glossary, best references, and other resources, is also included.The book narrows the knowledge and expertise chasm between data scientists, cardiologists, and cardiac surgeons, inspires these clinicians to embrace artificial intelligence methodologies, and educates data scientists about the cardiac ecosystem to create a transformational paradigm for cardiovascular healthcare that improves patient outcomes.

  • Our Genes, Our Choices

    How Genotype and Gene Interactions Affect Behavior
    • 2 Edición
    • David Goldman
    • Inglés
    Our Genes, Our Choices: How Genotype and Gene Interactions Affect Behavior, Second Edition explains how the complexity of human behavior, including concepts of free will, derives from a relatively small number of genes which direct neurodevelopmental sequences. Are people free to make choices or do genes determine behavior? Paradoxically, the answer to both questions is "yes," because of neurogenetic individuality, a new theory with profound implications. Here, author David Goldman uses judicial, political, medical, and ethical examples to illustrate that this lifelong process is guided by individual genotype, molecular and physiologic principles, as well as by randomness and environmental exposures.Written in an authoritative yet accessible style, the book includes practical descriptions of the function of DNA, discusses the scientific and historical bases of genethics, and introduces the topics of epigenetics and the predictive power of behavioral genetics.

  • Ethics for Health Promotion and Health Education

    • 1 Edición
    • Jody Vogelzang
    • Inglés
    Ethics for Health Promotion and Health Education discusses ethical principles and interpretations by classical ethicists as they apply to health promotion and health education. The book unpacks ethical expectations in promoting and teaching health in both the classroom and as a researcher or practitioner and then applies the code of ethics using case study methods throughout. This informative text was written by health educators and practitioners to assist health educator and practitioner communities.

  • Nanostructured Materials

    Physicochemical Fundamentals for Energy and Environmental Applications
    • 1 Edición
    • Zesheng Li + 1 más
    • Inglés
    Nanostructured Materials: Physicochemical Chemistry Fundamentals for Energy and Environmental Applications summarizes research knowledge and helps advanced students, researchers and industrial technicians understand specific applications of nanomaterials in energy and the environment. Sections bring a strong foundational focus on the physicochemical basis of nanomaterials for these applications, the basic theory and physicochemical basis of nanomaterials, an energy and environment applications examination of typical cases, and progress. This book will appeal to researchers in the chemical sciences (inorganic and physical chemistry, coordination chemistry, molecular dynamics, electrochemistry, photocatalysis, thermocatalysis, thermodynamics, etc.), nanoscience (graphene, carbon nanotubes, nanocrystals, nano catalysis, energy, and environment-nano science), and more. Efficient use of energy, eco-friendly environmental systems, and technologies play an important role in global sustainable development. Multifunctional nanocomposites have excellent properties and can meet the practical needs of energy development and environmental treatment. They have been gradually applied in chemical materials, energy preparation, pollution control and other fields and have achieved impressive development.

  • Acrylamide in Food

    • 2 Edición
    • Vural Gokmen + 1 más
    • Inglés
    Acrylamide in Food, Second Edition, is fully updated with four new chapters that incorporate current literature on acrylamide, including analysis, formation mechanisms, levels in foods, reduction strategies, and new regulations, such as the one made by the European Union in 2017 regarding the presence of acrylamide in processed foods. The book comprises of four parts: part one introduces acrylamide and the food chain in the context of harm and health. Part two focusses on acrylamide in various types of foods, such as bakery products, fried potato products, coffee, battered products, water, table olives, etc. Part three highlights its interaction mechanisms and health effects. Part four discusses methods of analysis. Acrylamide in Food, Second Edition is edited by a team of international experts in the field and is a quality reference in the developing field of acrylamide in food. It is valuable to researchers in the food industry or working on evaluating the factors affecting the formation of acrylamide in different heat-treated foods and the possibilities of reducing acrylamide formation accordingly.

  • Advances in Parasitology

    • 1 Edición
    • Volumen 122
    • David Rollinson + 1 más
    • Inglés
    Advances in Parasitology, Volume 122, the latest release in this ongoing series, includes medical studies of parasites of major influence, along with reviews of more traditional areas, such as zoology, taxonomy and life history.

  • Advances in Cancer Research

    • 1 Edición
    • Volumen 160
    • Inglés
    Advances in Cancer Research, Volume 160, the latest release in this ongoing, well-regarded serial, provides invaluable information on the exciting and fast-moving field of cancer research, with this updated edition covering PFKP: More Than Phosphofructokinase, Setting sail: maneuvering SHP2 activity and its effects in cancer, Mechanical factors driving cancer progression, Microsomal Glutathione Transferase 1 in Cancer and the Regulation of Ferroptosis, Lnc-ing epigenetic mechanisms with autophagy and cancer drug resistance, Head and Neck Cancer Treatment in the Era of Molecular Medicine, Applications of Tissue-Specific and Cancer-Selective Gene Promoters for Cancer Diagnosis and Therapy, and more.

  • Epigenetic Regulation of Cancer - Part A

    • 1 Edición
    • Volumen 380
    • Inglés
    Epigenetic Regulation of Cancer - Part A, Volume 380 in the International Review of Cell and Molecular Biology series, presents content from various experts in epigenetics who cover multiple facets of cancer-associated epigenetic alterations, including the impact of epigenetic deregulation in all steps of oncogenesis as well as promising strategies to therapeutically target cancer-associated epigenetic deregulation. Specific chapters cover Epigenetic regulation of epithelial-mesenchym... transition during cancer development, Novel insights into DNA methylation-based epigenetic regulation of breast tumor angiogenesis, Super-enhancer landscape rewiring in cancer: The epigenetic control at distal sites, Non-coding RNAs in the epigenetic landscape of Cutaneous T-cell lymphoma, and much more.

  • ZIP Metal Ion Transporters

    • 1 Edición
    • Volumen 687
    • Inglés
    ZIP Metal Ion Transporters, Volume 684 in the Methods in Enzymology series, highlights new advances in the field with this new volume presenting interesting chapters on a variety of topics, including Biochemistry, Biophysics and Structural Biology, Structure determination of a bacterial ZIP in lipidic cubic phase, Cell-based metal transport assay for animal and plant ZIPs, Measurement of metal binding affinity and transport activity in ZIP transporters using spectroscopic methods, Considerations in production of the (prokaryotic) ZIP family transporters for structural and functional studies, Metal-protein interactions investigated using model systems: thermodynamic, spectroscopic and computational methods, and more. Additional chapters cover Getting Zinc Into and Out of Cells, In-silico modeling of ZIP9 (TBD), Cellular Function and Regulation, Methods to visualize zinc transporter proteins of the SLC39A family in cells, Assessing metal ion transporting activity of ZIPs: intracellular zinc and iron detection, In vitro studies for studying manganese transport and homeostasis, and much more.

  • Stem Cell in Medicine

    • 1 Edición
    • Volumen 199
    • Inglés
    **Association of American Publishers (AAP) PROSE Award Finalist in Biomedicine and Neuroscience, 2024**Stem Cells in Medicine, Volume 199 in the Progress in Molecular Biology and Translational Science series, provides the most topical and informative research in the field of stem cells. Sections in this new release update on an Introduction to stem cells, Stem cell engineering, Xeno-free culture and proliferation of hPSCs on 2D biomaterials, 3D scaffold preparation for stem cell culture and differentiation, GMP grade production of hPSCs, Human hepatic stem cell assay, Cardiomyocyte cell sheets derived from hPSCs and muscle cells for myocardial infarction treatment, Stem cell therapy for osteoarthritis, hPSC-derived RPE transplantation for the treatment of macular degeneration, and much more.The book provides not only fundamental aspects and cultural and production methods of stem cells, but also the critical engineering aspects of stem cells such as drug screening using hepatocytes and disease treatment by transplantation of retinal pigment epithelium and cardiomyocytes which are derived from human pluripotent stem cells.

  • Metalloenzymes

    From Bench to Bedside
    • 1 Edición
    • Claudiu T. Supuran + 1 más
    • Inglés
    Metalloenzymes: From Bench to Bedside offers a thorough overview of metalloenzymes, spanning biochemical and structural features, pharmacology, and biotechnological applications. After a brief overview, international experts in the field discuss a wide range of magnesium, calcium, zinc, manganese, nickel, iron, copper, cadmium, molybdenum, and tungsten enzymes, along with catalytic roles within their active sites. With a uniform approach throughout, each chapter includes the structure and function of the enzyme, physiologic and pathologic roles, inhibitors and activators of the enzyme (and their design), and clinical agents or compounds applied in medicine and drug discovery. This book enables scientists across academia and industry to adopt ongoing metalloenzyme research, and continuous discovery of novel metalloenzymes, in new life science studies and clinical applications.

  • Bone Cell Biomechanics, Mechanobiology and Bone Diseases

    • 1 Edición
    • Ai-Rong Qian + 1 más
    • Inglés
    Bone Cell Biomechanics, Mechanobiology and Bone Diseases provides a comprehensive overview of recent knowledge and advances of bone cell biomechanics and related bone diseases, highlighting the cellular basis for bone responding to mechanical stimuli. The book not only provides a general overview of bone cell biology, but also the most recent advances of bone cell biomechanics, mechanobiology, the relationship between bone cell biomechanics and bone diseases, as well as the underlying mechanism. This will be useful in understanding the role of mechanobiology in bone health and bone diseases, as well for investigating novel strategies for diagnosis and therapy of bone diseases. Cells covered in the book include osteocyte, BM-MSC, osteoblast, osteoclast and chondrocyte. Cone diseases covered are osteoporosis, scoliosis and osteoarthritis. This comprehensive reference is written for researchers, scientists, clinicians and students.

  • Brain and Crime

    • 1 Edición
    • Volumen 197
    • Hanna Swaab + 1 más
    • Inglés
    Brain and Crime, Volume 197 reviews the relation between brain function and aggressive and rule-breaking (criminal) behavior. The book's focus is on the violation of social rules and not on violation of regulations that are different in different counties. It discusses the development of this behavior from childhood into adulthood, along with the mechanisms associated with the risk for aggression and rule-breaking behavior. In addition, it explores from a behavioral level concepts like psychopathology, syndrome and concepts from law, such as crime, defendant and offender. Finally, sections explore brain function, including emotion, cognitive processes, and decision-making. From the perspective of brain structure, the book covers brain networks and brain disorders. In genetics, the book includes the influence of genes and the mechanisms of epigenetics. All chapters are intended to provide information for use in the diagnosis and treatment of disorders, and in assessment and prevention.

  • Nutrition and Neurological Disorders

    • 1 Edición
    • Colin R. Martin + 2 más
    • Inglés
    Nutrition and Neurological Disorders offers readers a comprehensive reference on the effect of dietary regimes in a wide variety of neurological diseases. With its broad coverage of different types of diets, including the Mediterranean diet, this book allows readers to learn about the results of diets and their correlation with specific disorders. This includes diseases such as Alzheimer’s, Parkinson’s, ALS, and MS and severe neurological conditions such as brain injury, stroke, headache and migraine. Examining various compounds, the book's broad coverage allows readers to learn more about the role nutrient deficiency plays in the pathology of many conditions, along with treatment potential. This volume provides a platform for research on vitamins and minerals and on future investigations of these compounds.

  • History of Food and Nutrition Toxicology

    • 1 Edición
    • Esther Haugabrooks + 1 más
    • Inglés
    **Selected for Doody’s Core Titles® 2024 in Nutrition**History of Food and Nutrition Toxicology, part of the History of Toxicology and Environmental Health series, provides an overview of history in the field to help readers better understand future applications for evaluating newer and valuable approaches and their impacts on human health. The book explores issues associated with chemical contaminants, toxicants, the use of dietary supplements and pharmaceuticals, and increasing concerns surrounding food toxicity and safety. The addition of historical case studies and end-of chapter questions make the book ideal for toxicologists, food scientists, pharmaceutical scientists, and other researchers who want to understand current state and future challenges in the field.

  • Neuroethics and Neurodevelopment

    • 1 Edición
    • Volumen 6
    • Inglés
    This volume focuses on topics at the intersection between neuroethics and neurodevelopment, and brings together the perspectives of experts in both clinical assessment and intervention, and researchers in child psychology, neurosciences, medicine, health policy, law, and social work. The goal is to review emerging issues related to the ethical ramifications of how variation in human neurodevelopment is described, and the effects of these descriptions on those with lived experience, clinical and intervention services, and health and social policy. Related topics are also explored including the effect of the Covid-19 pandemic, the ethics of invasive neurotechnology interventions, biomarkers, machine learning, precision medicine.

  • Foundations of the Mind, Brain, and Behavioral Relationships

    Understanding Physiological Psychology
    • 1 Edición
    • Jahangir Moini + 2 más
    • Inglés
    Foundations of the Mind, Brain, and Behavioral Relationships: Understanding Physiological Psychology is an engaging introduction into neuroscience, and the portions of the nervous system, perception, and the clinical considerations in physiological psychology. "Clinical Applications" appear throughout the chapters and provide real-world examples of brain–behavior relationships, and how the nervous system interacts with other body systems to create a specific behavior. Creating an interactive experience for learners, this volume connects the study of neuroanatomy and neurophysiology with clinically relevant topics, ranging from stress and eating disorders to substance abuse, major affective disorders, and schizophrenia. Integrating the foundations of neuroscience with disorders encountered in clinical practice serves as a foundation to better understand the clinical bases of these conditions. Coauthored by clinical neuropsychologists, this book is for those interested in learning about the underpinnings of the mind, brain, and human behaviors in normal and divergent functioning.

  • Modeling of Post-Myocardial Infarction

    ODE/PDE Analysis with R
    • 1 Edición
    • William E. Schiesser
    • Inglés
    Modeling of Post-Myocardial Infarction: ODE/PDE Analysis with R presents mathematical models for the dynamics of a post-myocardial (post-MI), aka, a heart attack. The mathematical models discussed consist of six ordinary differential equations (ODEs) with dependent variables Mun; M1; M2; IL10; Tα; IL1. The system variables are explained as follows: dependent variable Mun = cell density of unactivated macrophage; dependent variable M1 = cell density of M1 macrophage; dependent variable M2 = cell density of M2 macrophage; dependent variable IL10 = concentration of IL10, (interleuken-10); dependent variable Tα = concentration of TNF-α (tumor necrosis factor-α); dependent variable IL1 = concentration of IL1 (interleuken-1). The system of six ODEs does not include a spatial aspect of an MI in the cardiac tissue. Therefore, the ODE model is extended to include a spatial effect by the addition of diffusion terms. The resulting system of six diffusion PDEs, with x (space) and t (time) as independent variables, is integrated (solved) by the numerical method of lines (MOL), a general numerical algorithm for PDEs.

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