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Elsevier

Libros en Ciencias de la Vida

  • Topical Dermal Drug Delivery

    Concepts and Advances
    • 1 Edición
    • Jitender Madan + 4 más
    • Inglés
    Topical Dermal Drug Delivery: Concepts and Advances compiles, in a single volume, the most recent advances in topical and dermal formulations for the treatment of skin disorders.The book covers three major concepts. The skin anatomy and physiology part includes chapters focused on relevant information for drug delivery. The second part of the book deals with several recent topical dermal drug delivery systems, including computational methods, permeation enhancers, bio precursors, hydrogels, emugels, exosomes and several nanotechnology enabled systems. The third and final part covers scaling up, toxicity, clinical trials, and regulatory considerations.This is a complete reference for academic and corporate pharma researchers investigating targeted drug delivery to the skin. Medical & Health Sciences researchers would also benefit from understanding the delivery systems covered in this book.

  • RNases in Health and Diseases

    From Housekeeping Enzymes to Moonlight Proteins
    • 1 Edición
    • Ester Boix
    • Inglés
    RNases in Health and Diseases: From Housekeeping Enzymes to Moonlight Proteins provides coverage of the structural and functional properties of RNases, introducing new concepts such as their recently discovered multifaceted properties, their involvement in the generation of non-coding signaling RNAs, and their proposed uses as diagnostic and therapeutic tools. This book's sections cover the structure of RNases, present research methods and tools to study RNases, and delve into RNases and diseases. Users will find a wider perspective on the topics discussed that will serve researchers and students engaged in the study of RNases who are interested in acquiring a better understanding.

  • Advances in Agronomy

    • 1 Edición
    • Volumen 200
    • Inglés
    Advances in Agronomy, Volume 200, the latest release in this leading reference on agronomy, contains a variety of updates and highlights new advances in the field, each written by an international board of authors.

  • Innovative Strategies Against Blood Parasites

    Advancing Control Through Natural Products and Next-Generation Technologies
    • 1 Edición
    • Mohamed Dkhil
    • Inglés
    Innovative Strategies Against Blood Parasites: Advancing Control Through Natural Products and Next-Generation Technologies explores innovative strategies for controlling blood parasitic diseases by combining natural products with next-generation technologies like nanotechnology and AI. The book provides a multidisciplinary approach to developing sustainable, effective, and accessible therapies to combat drug resistance and improve patient outcomes. Bridging traditional pharmacognosy with modern biomedical advances, the volume covers natural antiparasitic compounds, nanomedicine-based delivery systems, and computational tools such as genomics and machine learning.It features case studies, practical applications, and future perspectives, serving as an essential resource for researchers, clinicians, policymakers, and students involved in parasitology, tropical medicine, and drug discovery.

  • Cognitive Remediation in Psychiatric Disorders Part B

    Other Conditions, Contexts and Considerations
    • 1 Edición
    • Volumen 306
    • Inglés

  • Advances in Biomedical Engineering - Part B

    • 1 Edición
    • Volumen 405
    • Inglés
    Advances in Biomedical Engineering – Part B, Volume 405 presents the latest developments, research trends, and methodologies in the evolving field of biomedical engineering. This volume covers a range of topics, including advanced medical devices, biomaterials, biomedical imaging, tissue engineering, biomechanics, and computational modeling. Specific chapters in this new release include Advances in biomedical engineering, Recent advances in nanomedicine as drug delivery system, Advances in Nano biomaterials for Biomedical Engineering, Neurodiagnostic: Advances in diagnostic tools, Advances in Ferroptosis Research and Application, Bioink-based 3D Bioprinting: Paving the Path for Regenerative Medicine, MRI Acute/Sub-Acute Ischemic Stroke Segmentation with Deep Learning: A Comprehensive Review, and more.Contributions from leading experts highlight both theoretical advancements and practical applications designed to improve healthcare diagnostics, treatment, and patient outcomes. This comprehensive resource is ideal for researchers, practitioners, and students seeking to stay informed about cutting-edge technologies and future directions in biomedical engineering.

  • Wearable Smart Sensing Devices for Sustainable Healthcare

    Techniques, Fabrication, Data Collection and Analysis
    • 1 Edición
    • Arpana Parihar + 2 más
    • Inglés
    Wearable Smart Sensing Devices for Sustainable Healthcare: Techniques, Fabrication, Data Collection and Analysis presents a complete overview of the techniques for developing integrated wearable sensors, the systems that power them, and the fabrication issues involved in making them. The book bridges the gap between theory and practice, offering scientific knowledge and practical insights. Written by renowned researchers and industry experts, this book provides valuable understanding and insights into the design, data processing, analysis, and fabrication of wearable sensors that is ideal for academic engineering and scientific researchers, industry engineers, and scientists interested in developing wearable sensor devices.

  • Microbial Fertilizers

    Innovations and Applications for Sustainable Agriculture
    • 1 Edición
    • Laurent Dufossé + 3 más
    • Inglés
    Microbial Fertilizers: Innovations and Applications for Sustainable Agriculture explores the latest developments, applications, and challenges in the formulation and commercialization of novel microbial-based biofertilizers. Covering a wide array of topics, the book begins by covering the selection and diversity of microbial fertilizers. It explores the molecular and biochemical mechanisms of their plant-microbe interactions and how they can enhance nutrient availability and improve environmental stress tolerance. Additionally, the book addresses the commercialization and market trends of microbial fertilizers like the use of formulation technologies to improve microbial viability and stability in various product formats for better practical application.The book also explores cutting-edge omics approaches that facilitate comprehensive profiling of microbial communities and their roles in soil fertility and plant health as well as innovative technologies like the integration of synthetic biology and genetic engineering to tailor microbial strains for specific functions and the use of nanotechnology with microbial fertilizers for targeted nutrient delivery and controlled release systems. With a focus on overcoming the environmental challenges and leveraging opportunities for sustainable application, this book is an essential resource that provides insights into how microbial fertilizers can contribute to sustainable agriculture in the face of climate change.

  • Microbial Biofilms and Cancer

    • 1 Edición
    • Volumen 224
    • Inglés
    Microbial Biofilms and Cancer series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Artificial Intelligence and the Water-Energy-Food Nexus

    Innovations for Sustainable Resource Management
    • 1 Edición
    • Ali Fares
    • Inglés
    Artificial Intelligence and the Water-Energy-Food Nexus: Innovations for Sustainable Resource Management is a groundbreaking exploration on how AI transforms the management of our planet's most vital resources. Specific topics include enhancing poultry production and the predictions of crop yields and post-harvest processing, while also dealing with FEW security in sub-Saharan Africa. Additionally, the book covers various topics that showcase AI's potential to boost agricultural productivity, mitigate climate change, and promote food security. This book's content covers ethical considerations, interdisciplinary collaboration, and the integration of AI into real-world practices.Readers will find an in-depth analysis of the intersections of AI and the FEW Nexus, including the critical need for sustainable farming practices, water conservation, and energy efficiency. Contributing authors are experts from around the globe who offer practical solutions, case studies, and cutting-edge technologies like digital twins, machine learning, and hyperspectral imaging to optimize resource management.

  • Chia Seeds

    Applications in the Agri-food Industry
    • 1 Edición
    • Shivani Pathania + 2 más
    • Inglés
    Chia Seeds: Applications in the Agri-food Industry is a comprehensive guide to the properties of chia biomass (seeds, leaves, and ingredients/products thereof) and their utilization in the agri-food industry and beyond. The book is based on the analysis of chia value chain and summarizes the scientific, technical, and health aspects of chia (Salvia hispanica L.). Divided into 3 sections, it fills a critical gap in the literature by providing a comprehensive overview of chia biomass available to address key global bioeconomy and United Nation Sustainable Development Goals (SDGs) challenges.User will find advanced information for the utilization of chia-based biomass based on their specific properties, application of eco-efficient technologies for their processing and conversion into a variety of products for different groups of consumers, including those with special needs (e.g. celiac patients, vegans and vegetarians). In addition, the book offers practical guidance on the development of new value chains and their integration within the existing agri-food systems.

  • Nutritional and Health Aspects of Food in Oceania

    • 1 Edición
    • Diana Bogueva + 1 más
    • Inglés
    Nutritional and Health Aspects of Food in Oceania provides an analysis of traditional and ethnic foods from Australia, New Zealand, Fiji, Papua New Guinea, Tonga, Hawaii, Samoa, Tuvalu, Solomon Islands, and New Caledonia. The book addresses the history of use, origin, composition, preparation, ingredient origin, nutritional aspects, and effects on health for various foods and food products in each of these countries. In addition, it presents both local and international regulations while also providing suggestions on how to harmonize these regulations to promote global availability of these foods.

  • Advances in Food Security & Sustainability

    • 1 Edición
    • Volumen 11
    • Inglés
    Advances in Food Security and Sustainability, Volume 11, highlights recent developments and emerging perspectives in addressing global food security challenges. This volume brings together a diverse collection of chapters written by international experts, examining the complex interactions between food systems, health, environmental sustainability, and technological innovation. Chapters in this release explore topics such as the role of artificial intelligence and machine learning in food safety, the One Health approach to food security, regional perspectives on food security in the Americas, and the relationships between diet, health, and medical outcomes, and much more.Further chapters discuss policy environments influencing food security, the application of decision analysis methods for food safety, and strategies to address micronutrient deficiencies through biofortification. The volume also addresses global and regional issues including meat consumption trends in Africa, protein security in Central Asia, the legacy of the Green Revolution, and the role of biodiversity and marine ecosystems in sustaining resilient food systems. ]

  • miRNA in Human Disease

    From Biomarkers to Therapeutics
    • 1 Edición
    • Parul Gupta + 6 más
    • Inglés
    miRNA in Human Disease: From Biomarkers to Therapeutics explores the critical role of microRNAs (miRNAs) in the development and progression of various diseases, emphasizing their significance as biomarkers and therapeutic targets. Sections provide a comprehensive overview of the biogenesis, function, and regulation of miRNAs, offering insights into how these small noncoding RNA molecules influence gene expression and contribute to disease development and progression. The book covers traditional and advanced methods for miRNA extraction, the role of miRNAs in infectious diseases, cancer, neurological disorders, cardiovascular disease, hemoglobinopathies, pregnancy complications, and metabolic disorders.Sections also discuss the latest research on miRNA-based therapies, including the design and delivery of miRNA mimics and inhibitors and their potential applications in personalized medicine. With a strong focus on practical implementation, the book includes detailed case studies and real-world examples that demonstrate the clinical relevance of miRNA research. It addresses the challenges and future directions in the field, providing a roadmap for researchers, clinicians, and industry professionals to harness the potential of miRNAs for disease diagnosis, treatment, and prevention.

  • Sustainable Agriculture

    Technologies, Application, and Practices
    • 1 Edición
    • Wasswa Shafik
    • Inglés
    Sustainable Agriculture: Technologies, Application, and Practices provides readers with a foundational understanding of sustainable agriculture principles alongside the cutting-edge capabilities of artificial intelligence. Structured into six well-organized sections, the book begins with foundational concepts of sustainability and the enabling technologies that support them. This includes in-depth discussions on the principles of sustainability, the role of technology in enhancing agricultural practices, and the socioeconomic impacts of sustainable farming. Subsequent chapters look into practical applications, showcasing how smart irrigation, crop monitoring, and supply chain optimization can significantly bolster sustainable operations.Each chapter provides case studies and practical strategies to ensure a thorough understanding of how artificial intelligence can revolutionize sustainable agriculture. This book serves as an essential resource for upper-level undergraduate and graduate students studying sustainable agriculture, agricultural technology, and environmental science.

  • Analytics and Laboratory Testing Protocols for Halal Food and Non-Food Products

    • 1 Edición
    • Syed Ghulam Musharraf
    • Inglés
    Analytics and Laboratory Testing Protocols for Halal Food and Non-Food Products is a comprehensive exploration of the diverse field of Halal research and laboratory testing that dives into the scientific advancements necessary for ensuring compliance with Halal standards. The book introduces readers to methodologies and technologies used in laboratory testing, equipping them with the knowledge needed to adopt best practices and ensure compliance with Halal standards. It offers guidance on quality assurance measures and testing protocols, enabling readers to uphold the highest standards of Halal authenticity and enhance consumer confidence and brand reputation.This is an essential resource for graduate students and researchers in food sciences, analytical chemistry, and pharmaceutical sciences who want to check non-Halal ingredients and stay up-to-date with the latest developments in Halal assurance and quality control.

  • Patient Treatment and Management Following an Osteoporotic Vertebral Compression Fracture

    • 1 Edición
    • Douglas P. Beall
    • Inglés
    Worldwide, vertebral compression fractures (VCFs) continue to be the most common major fragility fracture, affecting patients over the age of 50, and osteoporosis is the most prevalent condition associated with VCFs. Patient Treatment and Management Following an Osteoporotic Vertebral Compression Fracture provides treatment and management guidance of the osteoporosis disease process in patients who have had a VCF. This book opens with a foundation of osteoporosis and VCF and then reviews clinical and radiological assessment approaches, evaluation, treatment, and ongoing management options. Subsequent chapters cover the efficacy of the different vertebral augmentation types on patient outcomes, optimization methods, decisions for osteoporosis treatment in these patients, and recommendations to improve patient outcomes. Special attention is paid to the treatment sequence and objectives following an osteoporotic VCF. This book concludes with coverage of insightful developments in clinical management and current research and features targeted case studies representing common patient characteristics that showcase varying aspects of different VCFs and the underlying osteoporosis that gives rise to these fractures. This title serves as an invaluable resource for any practitioner managing fragility fractures in older patients as well as treating their underlying osteoporosis.

  • Therapeutic Potentials of Tenofovir Alafenamide in Hepatitis B

    • 1 Edición
    • Lung-Yi Loey Mak + 1 más
    • Inglés
    Therapeutic Potentials of Tenofovir Alafenamide in Hepatitis B offers a comprehensive examination of the therapeutic potentials of Tenofovir Alafenamide (TAF) in hepatitis B, providing a succinct and up-to-date summary of all relevant evidence for this first-line oral antiviral agent. The text delves into key topics such as the pharmacological profile of TAF, its comparative efficacy against traditional antiviral agents, safety and tolerability, and the impact of TAF on drug resistance. Additionally, it explores the use of TAF in special populations, including pediatrics, the elderly, and individuals with renal impairment, as well as future directions in hepatitis B treatment strategies.Readers will discover the diverse potential applications of TAF in chronic hepatitis B, informed by valuable lessons learned from HIV treatment while also gaining insights into future therapeutic possibilities. Authored by leading experts in the field, each chapter presents focused and insightful perspectives, making this book an indispensable resource for practitioners and researchers alike. Serving as a critical resource for physicians, researchers, pharmacologists, and biomedical scientists, this book highlights the core knowledge necessary for understanding TAF and its clinical applications.

  • Advances in Marine Biology

    • 1 Edición
    • Volumen 104
    • Inglés
    Advances in Marine Biology, Volume 104, the latest release in this serial that highlights new advances in the field, includes comprehensive chapters written by an international board of authors. Chapters in this new release explore Integrative Fish Biomechanics and Advancing marine invertebrate biodiversity in South Africa: Addressing gaps in taxonomy and genetic knowledge.

  • Foundation of Microfluidics Device Technology

    • 1 Edición
    • Volumen 225
    • Inglés
    Foundation of Microfluidics Device Technology, Volume 225 presents the fundamentals of microfluidics and microfluidics devices, including computational design and fabrication, artificial intelligence and internet of things for microfluidics devices, materials, surface modifications and functionalization of microfluidics, fabrication of paper based microfluidics. Additional topics include microfluidics for generation of biomaterials, microfluidics for multi-omics analysis, lab-on-the-chip, microfluidics for 2D and 3D cell culture systems, microfluidics for drug and gene delivery, biomimetic models, and the economic considerations associated with microfluidics devices development.Specific chapters in this new release include An introduction to microfluidics and devices, Computational design and modeling of microfluidics devices, Artificial intelligence and IoT for microfluidics devices, Fabrication techniques for design of microfluidics devices, Materials, surface modification and functionalization of microfluidic devices, Fabrication of paper based microfluidics, Microfluidics in biomaterials generation and formulation, Microfluidics for chemical and biological analysis, and more.

  • Enzyme Microfluidics

    • 1 Edición
    • Volumen 737
    • Inglés
    Enzyme Microfluidics, Volume 737 in the Methods in Enzymology series, presents detailed methodological descriptions and protocols that cover a wide range of microfluidics-based approaches for mechanistic enzymology, high-throughput screening, and enzyme engineering campaigns. The volume includes both established methods as well as advances in the field. Sections in this new release cover four unique sections, including Chips and Reagents, Enzyme Characterization, Enzyme Engineering, and Moving Beyond Microfluidics (from micro to nanoscale). Specific chapters delve into Joint Methods for Fabricating Microfluidic Chips, A liquid handling robotic workflow for quantifying the activity of antibiotic resistance genes (ARGs) in cell-free protein synthesis, and much more.Additional chapters cover Preparation of uniform microcrystals by droplet microfluidics for time-resolved serial crystallography, Droplet microfluidic HDX for investigating highly dynamic proteins, An Accessible, Low-Cost Platform for High-Throughput Microfluidic Enzyme Kinetics, High-Throughput Data Processing, DA-MEK, Mass Spectrometry of Droplets, Digital Bioassay Using a Femtoliter Reactor Array Device, Confocal absorbance droplet sorting, Sequence-Function Data Analysis from Microfluidics Screening, and much more.

  • Glycobiology of the Immune System and Disease

    • 1 Edición
    • Shyamasree Ghosh + 1 más
    • Inglés
    Glycobiology of the Immune System and Disease explores the integration of state-of-the-art glycobiology and immunology to raise awareness of the multifaceted roles of glycans and lectins in the immune system. Glycobiology is a rapidly growing field in biology, with relevance to biomedicine, biotechnology and basic research. Considering the central role that glycans play in immune interactions, glycoproteins and carbohydrates are becoming the targets of next-generation therapeutics, vaccines and diagnostics. Programmed remodeling of host glycans can modulate infection, autoimmunity, and cancer, while microbial glycoconjugates can serve as canonical innate receptor agonists that induce B cell and T cell activation. This important reference investigates microbial and mammalian glycans and their protein-binding partners (lectins) and shows the role they play in all innate and adaptive immune responses. With its comprehensive overview of the field, it is an important resource for academicians, graduate and post graduate students as well as professors and faculty in the field of research in glycobiology and immunology.

  • Intelligent Semantic Analysis for Healthcare

    • 1 Edición
    • Sonali Vyas + 3 más
    • Inglés
    Intelligent Semantic Analysis for Healthcare explores the latest trends, developments, and future directions of intelligent semantic analysis techniques on retrieving and managing meaningful medical information for healthcare information systems. The book explores different computational methods, ideas, strategies, and techniques to analyze relevant healthcare information in an innovative and efficient way, thus bridging the gap between gathering and comprehending data with healthcare and biological applications. It offers a comprehensive view of intelligent semantic analysis in healthcare, bridging the gap between data collection and healthcare applications, and providing innovative computational methods for data analysis.Sections focus on intelligent semantic analysis rather than broader topics of big data and healthcare analytics. Additionally, the book is geared towards practical approaches and innovative techniques for state-of-the-art and current challenges in healthcare data management.

  • Advances in Biosensor Technology for Mycobacterium Tuberculosis Detection

    • 1 Edición
    • Mansi Chaturvedi + 3 más
    • Inglés
    Advances in Biosensor Technology for Mycobacterium Tuberculosis Detection provides an interdisciplinary overview of Mycobacterium tuberculosis (MTb) and various biosensing techniques for the Mycobacterium tuberculosis (MTb) detection and diagnosis. The book covers detailed information about the Mycobacterium tuberculosis bacteria, its pathogenesis, and the global health challenges caused by tuberculosis. It explores potential materials for biosensor development, the various types of biosensors integrated with electrochemical and fluorescence for the detection of Mtb and TB biomarkers, and their application in disease diagnosis.In addition, the book discusses the potential of advanced technologies, including AI, IoT, and POC devices for TB diagnosis. With contributions from experts in the field, this book is an informative resource for those interested in enhancing point-of-care diagnostics and accurate TB detection for the timely treatment of the disease.

  • Nitric Oxide in Plant Resilience to Abiotic Stress

    • 1 Edición
    • Ravi Gupta + 2 más
    • Inglés
    Nitric Oxide in Plant Resilience to Abiotic Stress offers a detailed examination of this essential gasotransmitter’s pivotal role in bolstering plant defenses against environmental stressors. Part of the Plant Gasotransmitters and Molecules with Hormonal Activity series, the volume investigates the molecular mechanisms of nitric oxide (NO) biosynthesis and signaling, emphasizing how post-translational modifications like S-nitrosylation and tyrosine nitration govern key targets to activate adaptive stress responses. It systematically examines NO’s properties, detection techniques, and its regulation under both optimal and adverse conditions, providing a comprehensive understanding of how it modulates plant functions.Expanding beyond fundamental processes, the volume highlights NO’s crucial involvement across a spectrum of abiotic stresses—drought, salinity, temperature extremes, heavy metals, and UV radiation—unveiling its capacity to mitigate damage and strengthen plant resilience. It also discusses the crosstalk between NO and other signaling molecules, such as phytohormones and emerging growth regulators, revealing synergistic pathways that underpin sustainable agriculture.Designed for researchers, advanced students, and plant scientists worldwide, this work illuminates the potential of NO to drive innovations in breeding strategies, enabling crop improvement to overcome the challenges posed by a changing climate and expanding environmental pressures.

  • Gene Therapy in Neurodegenerative Disorders

    From Bench to Bedside
    • 1 Edición
    • Vahid Mansouri + 1 más
    • Inglés
    Gene Therapy in Neurodegenerative Disorders: From Bench to Bedside offers a comprehensive review of gene therapy modalities and their applications in treating neurodegenerative disorders. Initial chapters focus on the fundamentals of gene therapy strategies, including gene delivery methods and CNS-targeted gene delivery. Subsequent chapters delve into specific neurodegenerative disorders such as Spinal Muscular Atrophy (SMA), Amyotrophic Lateral Sclerosis (ALS), Duchenne Muscular Dystrophy (DMD), and Alzheimer's Disease (AD), highlighting the latest gene therapy approaches for each condition. Each chapter provides a detailed introduction to the relevant field before exploring specific tools and applications.With contributions from leading experts, the book addresses current and ongoing clinical trials, potential challenges, and promising advances in gene therapy for neurodegenerative disorders. It also discusses regulatory and ethical considerations in translating research from bench to bedside. This book is an essential resource for basic science researchers in gene therapy, geneticists, biotechnologists, and clinical researchers seeking new and effective treatments for neurodegenerative diseases. It equips readers with the knowledge and tools needed to advance their work and drive innovation in gene therapy.

  • Advances in Transfusion Medicine

    A Practical Handbook
    • 1 Edición
    • Parmatma Prasad Tripathi
    • Inglés
    Advances in Transfusion Medicine: A Practical Handbook presents a detailed overview of transfusion medicine, beginning with blood components and derivatives therapy, including RBC, platelet, and plasma transfusions, as well as hematopoietic stem cell therapy. The book addresses patient blood management, focusing on practical applications and specific considerations in various populations. Safety practices in transfusion, including blood donation strategies and reactions are also covered. In addition, emerging therapies and technologies, such as artificial red blood cells and gene therapy are explored alongside global health challenges related to blood safety and shortages.The role of immunohematology and genomics is highlighted, along with cellular therapy applications, ethical considerations, and a discussion on pediatric transfusions and guidelines for managing transfusions in children. Miscellaneous topics like emerging infections and pathogen reduction technologies complete the overview, emphasizing current practices and future directions in the field.

  • Marine Mercury Bioaccumulation

    • 1 Edición
    • Luiz Drude de Lacerda
    • Inglés
    Marine Mercury Bioaccumulation presents state-of-the-art research on mercury bioaccumulation in marine life. Written by leading experts in marine toxicology, this book delivers the latest information on monitoring and modeling mercury biomagnification in key marine taxa. Early chapters introduce the basic biology and ecology of how mercury travels through marine organisms and accumulates within marine food webs. Central chapters discuss the current status and exposure risks of key taxa, including marine vegetation, invertebrates, fishes, mammals, and birds. The book concludes with an assessment of human exposure to mercury through seafood products and novel modeling tools to assess environmental exposure risks and bioaccumulation.User... will find this to be a great resource for a global assessment of mercury contamination in the ocean, including biological resources, monitoring and modeling, current tools, existing research gaps, and suggestions on how to improve our monitoring and policy tools for improved safety of marine life and human consumption. This is an indispensable tool for researchers, resource managers, fisheries stakeholders, and students alike.

  • Molecular Insights into Proteinopathies

    Increased Scope from Neurodegeneration to other Pathologies of the Brain
    • 1 Edición
    • Eva Žerovnik + 1 más
    • Inglés
    Molecular Insights into Proteinopathies: Increased Scope from Neurodegeneration to other Pathologies of the Brain investigates the molecular events that lead to various diseases. The book is divided into four parts, the first of which delves into protein aggregation across a range of diseases, including Alzheimer’s disease, Parkinson’s disease, schizophrenia, and neuropsychiatric diseases. It then moves on to discuss signaling pathways and biomarkers of disease, including oxidative stress, mitochondrial decline, and dysregulated molecular pathways. The third part explores small molecules as modulators of key processes in the pathogenesis of proteinopathies, including antioxidants, polyphenol compounds, metal chelators, and repurposed drugs that modulate proteinopathies.The final section considers biophysical methods, molecular dynamics, and machine learning approaches in the study of these aspects. The book provides a detailed overview of protein dysfunction and its implications for health and disease, aiding understanding of protein condensates and aggregates, protein misfolding, co-chaperoning and toxicity of pre-amyloid aggregates. By understanding the fundamental properties underlying these, the book paves the way for investigating how proteinopathies could be treated.

  • Evolutionary Adaptations and Mosquito-Borne Viruses

    • 1 Edición
    • Volumen 70
    • Inglés
    Evolutionary Adaptations and Mosquito-Borne Viruses comprises comprehensive reviews of various topics in mosquito adaptations and mosquito-virus interactions, with insights into future research prospects. The topics covered in this volume include mechanisms of insecticide resistance, thermal and desiccation tolerance, insect-specific viruses and their interactions with pathogenic viruses, mosquito viral immunity, factors affecting vector competence, host preference, saliva and viral pathogenesis, microbiota and symbionts, gene drives and genetic modification of mosquitoes, and microRNA roles in mosquito-virus interactions.

  • Intelligence-Based Healthcare

    Artificial Intelligence Concepts with Real‑World Applications for Healthcare Leaders and Providers
    • 1 Edición
    • Anthony Chang + 2 más
    • Inglés
    Intelligence-Based Healthcare: An Essential Guide with Case Studies of Artificial Intelligence for the Healthcare Leader and Provider is an essential guide with an introduction to data science and artificial intelligence to provide the reader with a quick orientation and education on AI in healthcare. This book also offers a framework for success in planning, deployment, implementation, and evaluation of AI models in healthcare. In 25 chapters, Intelligence-Based Healthcare: An Essential Guide with Case Studies of Artificial Intelligence for the Healthcare Leader and Provider both introduces the reader to artificial in medicine and healthcare, and AI concepts. To render AI more understandable and relatable to the reader, case studies are used as a learning strategy to illustrate the aforementioned AI concepts. The cases implement AI in solving a very specific problem, clinical or operational, in clinical medicine or healthcare. Both cases that illustrate successful implementation of AI as unsuccessful application cases with important lessons learned are included. Each chapter can be read independently and therefore the book is a valuable resource for researchers, health professionals, postgraduate students, post doc researchers and faculty members in the fields of artificial intelligence in medicine and healthcare, and all those who wish to broaden their knowledge in the allied field.

  • Beer and Brewing

    Current Advances and Future Outlook
    • 1 Edición
    • Charles W. Bamforth
    • Inglés
    Beer and Brewing: Current Advances and Future Outlook addresses key changes and challenges facing breweries today, and with an eye to the future. The book offers the latest in scientific research and technology for novel methods and ingredients, such as genetically modified yeasts. In response to the climate crisis and consumer demand for sustainable products, information on brewing process changes for lower waste and reduced impact will also be covered. Due to shifting consumer preferences, new product types such as spiked cider, low-alcohol, and alcohol-free beers will be discussed in addition to traditional beer.Edited by a true pillar of the field, the book approaches brewing on the basis of driving forces that are impacting the industry now and into the future. Researchers interested in applied brewing science, skilled small-scale brewers and other industry stakeholders will gain invaluable insight from Dr. Bamforth's latest work.

  • Advances in Genomics and Neurosciences for Neurologic and Behavioral Disorders

    • 1 Edición
    • Moyra Smith
    • Inglés
    Advances in Genomics and Neurosciences for Neurologic and Behavioral Disorders explores the latest breakthroughs in genomics and neurosciences, providing essential insights for understanding, diagnosing, and managing neurodevelopmental, psychiatric, and neurodegenerative disorders. The book highlights the intersection of genetic and genomic diagnostic techniques with brain function and structure analysis to enhance therapeutic strategies. Sections cover a wide range of topics, including the analysis of brain circuits, synapses, and neural activity, as well as the role of ion channels and neurotrophins in brain function. It examines advanced genetic and genomic diagnostic methods such as chromosome studies, gene sequencing, RNA analysis, and metabolite profiling.The book also addresses neurodevelopmental disorders like cerebral palsy, epilepsy, and autism, psychiatric disorders such as schizophrenia and thought disorders, and the molecular biology of memory and age-related cognitive decline. Organized into five sections, the book includes chapters on the latest techniques for brain analysis, genetic diagnostics, neurodevelopmental and psychiatric disorders, aging-related impairments, and new therapeutic approaches. Key topics include brain regions and circuits, new methods for studying these areas, and the relevance of this information for accurate diagnosis and patient care.

  • Advanced Technologies for Disease Intervention

    Innovations Across Precision Medicine, Nutrition and Holistic Therapies
    • 1 Edición
    • Ranbir Chander Sobti + 3 más
    • Inglés
    Advanced Technologies for Disease Intervention: Innovations Across Precision Medicine, Nutrition and Holistic Therapies, Two Volume Set investigates current and emerging advances in disease detection, diagnosis, treatment and prevention, and how molecular medicine and biotechnology have contributed to this changing landscape. Volume One focuses on sustainable health practices through biotechnology, exploring traditional health systems, diagnostic innovations, and integrative therapies. Key topics include: the role of traditional medicine and practices in sustainable health; contemporary and emerging technologies such as aptamer diagnostics, telemedicine, nanomaterials and AI in healthcare, and much more.Volume Two then delves deeper into emerging technologies for disease intervention, focusing on drug development, delivery systems, nutrition, and natural products for health. Themes explored here include: developments and trends in drug discovery; drug repurposing; contemporary drug delivery systems; phototherapeutics; personalized drug delivery; innovations in vaccine development; the role of nutraceuticals in disease prevention; and the use of natural products and herbal interventions for sustainable health.

  • Signaling Pathways in Breast Cancer

    Molecular Mechanisms, Therapeutic Strategies, and Multidrug Resistance
    • 1 Edición
    • Sumel Ashique + 3 más
    • Inglés
    Signaling Pathways in Breast Cancer: Molecular Mechanisms, Therapeutic Strategies, and Multidrug Resistance provides an in-depth exploration of the complex molecular mechanisms that drive breast cancer progression. The book focuses on critical signaling pathways, including PI3K/Akt/mTOR, MAPK/ERK, JAK/STAT, Wnt/β-catenin, and Notch, elucidating their roles in tumor development, survival, and therapeutic resistance. The content offers a comprehensive overview of these pathways, detailing their dysregulation in breast cancer and implications for targeted therapeutic strategies. It discusses FDA-approved treatments, emerging therapies, and the mechanisms behind drug resistance, integrating recent research findings to highlight novel molecular targets and biomarker discovery. This book serves as a valuable resource for researchers, clinicians, and students, bridging the gap between basic molecular biology and clinical applications. By providing structured insights into complex signaling networks and therapeutic interventions, it equips readers with essential knowledge for developing innovative approaches to breast cancer management and improving patient outcomes.

  • Navigating Health Research

    From Fundamentals to Advanced Practices in Biostatistics and Study Design
    • 1 Edición
    • Aliaa Rehan Youssef + 3 más
    • Inglés
    Navigating Health Research: From Fundamentals to Advanced Practices in Biostatistics is an essential resource for students, scientists, and clinicians embarking on their research journeys. This book clarifies research methodology and regulation while providing foundational knowledge in biostatistics through clear explanations and illustrative examples. Covering both classical and modern advancements in health research, it addresses topics such as health economics, artificial intelligence, and bioinformatics. The book offers a step-by-step guide through the research lifecycle, tackling challenges like study design flaws and ethical compliance. Emphasizing open-source software and freely available resources, it ensures accessibility for researchers from diverse socioeconomic backgrounds. With a multi-generational and multicultural perspective, this book enhances its relevance for a broad audience. By simplifying complex topics and promoting best practices, it empowers early-career researchers and clinicians to improve their skills, elevate the quality of their work, and contribute meaningfully to evidence-based practice in health research.

  • Advances in Parasitology

    • 1 Edición
    • Volumen 133
    • Inglés
    Advances in Parasitology series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Advances in Cancer Research

    • 1 Edición
    • Volumen 172
    • Inglés
    Advances in Cancer Research, Volume 172 in this ongoing series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Memantine and its Analogs: Potential Applications in Cancer Therapy, The role of epigenetic modifications in mediating cancer health disparities, Tumor Associated Macrophages: Ontogeny, Plasticity, Spatial Ecosystems, and Therapeutic Targeting, Recognizing the significance of cancer-nerve crosstalk in advanced prostate cancer, and much more.

  • Recent Advances in Molecular Docking

    Methods, Tools, and Applications
    • 1 Edición
    • Khalid Raza
    • Inglés
    Recent Advances in Molecular Docking: Methods, Tools, and Applications offers an authoritative guide to modern molecular docking techniques, emphasizing the integration of artificial intelligence and machine learning. The volume covers foundational principles, computational workflows, and advanced scoring functions, providing researchers and practitioners with practical tools to improve drug-target interaction predictions. It highlights applications across pharmaceuticals, including cancer, neurological disorders, and infectious diseases, which are all supported by real-world case studies. Challenges in docking accuracy, reproducibility, validation, and ethical and regulatory considerations are also covered.Authored by international experts, it bridges theoretical knowledge with practical applications, making it an essential resource for computational biologists, pharmacologists, and drug developers aiming to leverage AI-driven docking in precision medicine.

  • Metabolomic Phenotyping for the Future of Personalized Medicine

    Beyond the Biomarkers
    • 1 Edición
    • Jacopo Troisi + 1 más
    • Inglés
    Metabolomic Phenotyping for the Future of Personalized Medicine: Beyond the Biomarkers takes a critical look at the advancements in the field. It begins by explaining the essential steps of metabolomics analysis—from sample collection to data interpretation—while exploring how these workflows pave the way for targeted medical applications. With a focus on precision, it shows how metabolomics provides key insights into the mechanisms behind diverse phenotypes, making it an indispensable asset for biomedical research. The second section dives into the transformative results achieved in major medical domains through metabolomics, detailing how this emerging science contributes to understanding complex disease mechanisms.The book also outlines the international regulatory framework essential for conducting research within this field, ensuring compliance and ethical standards. By combining practical guidelines with visionary insights, this text serves as a cornerstone for future strides in personalized medicine and highlights the growing influence of metabolomics in shaping tomorrow’s healthcare systems.

  • Smart Biosensing Technologies for Early Detection of Metabolic Disorders

    • 1 Edición
    • Kanwal Rehman + 1 más
    • Inglés
    Smart Biosensing Technologies for Early Detection of Metabolic Disorders gives a clear overview of the latest biosensor tools that help detect and monitor metabolic diseases like diabetes, obesity, and insulin resistance early. It explains how these sensors work using basic science and shows new wearable, non-invasive, and easy-to-use devices. This book is useful for researchers, doctors, and professionals working in healthcare technology. This book connects research from different fields to help solve real problems in making and using biosensors. It includes examples of how these sensors are used, new markers for disease detection, and how AI and digital health can improve care. Readers will learn how to develop better diagnostic tools and improve treatment for metabolic diseases.

  • The Inflammatory Ecosystem and Inflammazones

    Mapping the Complex Terrain of Inflammatory Diseases
    • 1 Edición
    • Erwei Song + 1 más
    • Inglés
    The Inflammatory Ecosystem and Inflammazones: Mapping the Complex Terrain of Inflammatory Diseases offers a groundbreaking framework for understanding inflammation across multiple spatial and molecular levels. The book introduces the concept of distinct inflammazones—local, regional, distal, and systemic—and explores how their interactions influence disease development, progression, and resolution. This holistic approach integrates cellular, molecular, microbiome, and systemic responses, addressing a critical gap in current knowledge and advancing diagnostics and therapies for diseases like autoimmunity and cancer. The book is organized into six sections, starting with foundational principles and progressing through mechanisms of local, regional, and systemic inflammazones.It covers key components such as cytokines, chemokines, immune cells, and the roles of non-immune cells like fibroblasts and epithelial cells. The final sections focus on systems-level insights, including inflammaging, metabolism, and multi-omics technologies, culminating in strategies for personalized medicine and clinical translation. Each chapter combines cutting-edge research with clinical relevance, making complex concepts accessible and actionable.

  • Surgical and Non-Surgical Advances in Stroke Management and Therapeutics

    • 1 Edición
    • Creed M. Stary + 2 más
    • Inglés
    Surgical and Non-Surgical Advances in Stroke Management and Therapeutics offers a comprehensive exploration of contemporary stroke care. This essential resource synthesizes the latest research and clinical innovations, providing in-depth insights into advanced surgical techniques, emerging therapies, and interdisciplinary approaches to stroke treatment. Readers will gain a thorough understanding of both acute and chronic stroke management, enriched by expert commentary from leading clinicians and researchers. Covering everything from pioneering non-invasive interventions to state-of-the-art surgical strategies, this book delivers a critical framework for healthcare professionals dedicated to optimizing patient outcomes and rehabilitation.

  • Geriatric Neurosurgery in Clinical Practice

    • 1 Edición
    • Joe M. Das
    • Inglés
    Geriatric Neurosurgery in Clinical Practice is an essential resource that provides a thorough and modern overview of geriatric neurosurgery. This volume compiles the latest research and clinical practice guidelines, offering practical advice for clinicians caring for elderly patients. It delves into a range of topics, including the management of common neurosurgical conditions in elderly patients, surgical techniques, postoperative care, and the integration of multidisciplinary approaches to enhance patient outcomes. Users will find this to be an invaluable reference for practicing neurosurgeons, neurosurgery residents, neurologists, geriatric physicians, and researchers seeking clear and concise information on current treatments and procedures for geriatric neurosurgery.

  • Encyclopedia of Psychotherapy

    • 2 Edición
    • David Reitman + 1 más
    • Inglés
    Traditional encyclopaedias present information in alphabetical order and are somewhat held hostage to a static structure. A digital reference can be sorted and organised more dynamically. We take advantage of this more flexible structure by cross-referencing contributions so that readers can create their own structure, one that suits their learning needs and those of their students and trainees. For example, a reader could select “child and adolescent” entries and directly cross-reference with “behavioural or cognitive/behavioura... In this edition all content is updated, and most content areas will be retained, focusing on major modes of psychotherapy practice and core psychotherapy processes. Outdated entries have been culled or combined with other entries in a manner that better communicates the content to present-day readers (e.g., “water-misting therapy” can be addressed in a more cohesive entry covering the use of punishment techniques more generally).

  • Methods in Systems Bioinorganic Chemistry

    • 1 Edición
    • Volumen 741
    • Inglés
    Methods in Systems Bioinorganic Chemistry, Volume 741 provides understanding of high-level properties involving metals in biology that are founded on molecular or mechanistic level interactions. Currently, there is no established “tool kit” for studying bioinorganic systems, so the methods included in the book span a diverse range of topics and approaches, from imaging to proteomics, from metals-in-mice to mathematical modeling. Specific chapters cover Inductively Coupled Plasma Mass Spectrometry (ICP-MS)-based methods to quantify transition metals in cells and vertebrate models, ICP-MS elemental analysis in tissue samples, and much more.Additional chapters delve into An inductively-coupled-... triple quadrupole method with oxygen for the determination of essential elements and protein concentration, Calculating metal speciation of proteins inside cells, Probing biological copper in the subfemtomolar regime, Using LC-ICP-MS chromatography to detect and characterize Labile Metal Pools, Linking dynamic bioinorganic chemistry processes of toxic metals in the bloodstream to establish their exposure-response relationship in humans, Contextualizing X-ray fluorescent microscopy – high resolution X-rays meet subcellular morphology, Chemoproteomic profiling of transition metal binding sites in bacterial proteomes, Heme Labeling by Proximity (HeLP) to Identify Hemoproteins, and much more.

  • Advancing Sustainable Agriculture Through Arbuscular Mycorrhizal Fungi

    • 1 Edición
    • Allah Ditta + 2 más
    • Inglés
    Advancing Sustainable Agriculture Through Arbuscular Mycorrhizal Fungi provides a comprehensive view of AMF-focused approaches that support biodiversity, ecosystem services, and soil health. The book addresses the topic from the basis of symbiosis to the latest research and future directions of AMF use in agriculture. It provides a thorough overview of the role that AM fungi play in promoting agricultural sustainability and synthesizes current knowledge on the biology, ecology, and applications of AM fungi in sustainable agriculture, highlighting best practices for promoting AM fungi in agricultural ecosystems, such as crop selection, soil management, and fertilizer use. In addition, the book identifies research gaps and priorities for the advancement of the understanding of AM fungi in sustainable agriculture. Among the major issues confronting agriculture are soil erosion, water shortages, climate change, and dwindling biodiversity. In response to these issues, the need for sustainable farming methods that support ecosystem services, biodiversity, and soil health is rising. As the soil microbiome is largely composed of arbuscular mycorrhizal (AM) fungi, which are essential for preserving soil health and encouraging plant development, this book is a welcomed resource.

  • Recent Advances in Targeting Inflammation

    Ion channels, GPCR Signaling Tools, Therapies, and Beyond
    • 1 Edición
    • Senthilkumar Rajagopal + 3 más
    • Inglés
    Recent Advances in Targeting Inflammation: Ion Channels, GPCR Signaling Tools, Therapies, and Beyond delves into the multifaceted occurrences of inflammation across different systems, such as neuroinflammation and gastric inflammation. The book's main goal is to present the latest highlights, covering advancements in inflammation, investigational therapies, animal models, and biomarkers. These insights are crucial for better diagnosis, monitoring, and potential therapeutic options for patients suffering from both acute and chronic inflammation. This comprehensive work explores various topics, including ion channel regulation in inflammation, GPCR regulation, signaling pathways, and therapeutic approaches.It emphasizes the importance of understanding the role of ion channels, GPCR, and nutrition in managing inflammation effectively. Additionally, the book discusses the global impact of chronic inflammation on health outcomes, stressing the need for improved healthcare planning and strategies.

  • Basic Principles of Drug Discovery and Development

    • 3 Edición
    • Benjamin E. Blass
    • Inglés
    **Selected for 2026 Doody's Core Titles in Pharmacy**Basic Principles of Drug Discovery and Development, Third Edition presents a unique overview of the drug discovery and development program not available elsewhere. Each chapter provides sufficient technical details on the topics covered so that non-experts will have the tools and information necessary to interact and exchange information with colleagues across the entire spectrum of the drug discovery and development process. The drug discovery and development process involves individuals and teams with a wide array of expertise ranging from basic sciences (medicinal chemistry, biology) to applied science (pharmacology, pharmacokinetics, clinical sciences) to business driven fields (regulatory affairs, intellectual property experts, marketing specialists).The success or failure of a program focused on bringing a new medication to market often depends on clear communication between individuals and teams with vastly different expertise. As a result, it is critical that experts in one aspect of drug discovery and development (e.g., medicinal chemists) have a working understanding of the wide range of disciplines that take part in the overall process.

  • Engelking's Textbook of Veterinary Physiological Chemistry

    • 4 Edición
    • Kevin Connolly
    • Inglés
    Bridging the gap between basic and clinical science concepts, Engelking's Textbook of Veterinary Physiological Chemistry, Fourth Edition offers broad coverage of biochemical principles for students and practitioners of veterinary medicine. The only recent biochemistry book written specifically for the veterinary field, this updated text covers cellular-level concepts related to whole-body physiologic processes in a reader-friendly, approachable manner. Each chapter is written in a succinct and concise style that includes an overview summary section, numerous illustrations for best comprehension of the subject matter, targeted learning objectives, and end of the chapter study questions to assess understanding.With numerous illustrations and both instructor and student companion websites with updated PowerPoint images, lecture slides, and Snapcasts, Engelking's Textbook of Veterinary Physiological Chemistry, Fourth Edition, proves useful to students and lecturers from diverse educational backgrounds. Sectional exams and updated case studies extend the breadth and depth of learning resources.

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