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Elsevier

Libros en Ciencias de la Vida

  • Accelerating Strategic Changes for Digital Transformation in the Healthcare Industry

    • 1 Edición
    • Patricia Ordonez de Pablos + 1 más
    • Inglés
    Accelerating Strategic Changes for Digital Transformation in the Healthcare Industry discusses innovative conceptual frameworks, tools and solutions to tackle the challenges of mitigating major disruption caused by COVID-19 in the healthcare sector and society. It emphasizes global case studies and empirical studies, providing a comprehensive view of best lessons on digital tools to manage the health crisis. The book focuses on the role of advances in digital and collaborative technologies to offer rapid and effective tools for better health solutions for new and emerging health problems. Researchers, students, policymakers and members of the biomedical and medical fields will find this information invaluable. Specially, it pays attention to how information technologies help us in the current global health emergency and the coronavirus epidemic response, gaining more understanding of the new coronavirus and helping to contain the outbreak. In addition, it explores how these new tools and digital health solutions can support the economic and social recovery in the post-pandemic world.

  • Aptamers for Food Applications

    Safety, Authenticity, and Integrity
    • 1 Edición
    • Yiyang Dong
    • Inglés
    Aptamers for Food Applications: Safety, Authenticity, and Integrity outlines the main applications of aptamers to ensure food safety, quality and compliance that are crucial for food science, public health and human sustainability. Aptamers or aptamer-based analytical devices are comprehensively summarized to tackle various food contamination or food adulteration problems. Topics covered in this book include aptamers for foodborne microbial pathogens, pesticide or veterinary drug residues, heavy metals, biotoxins, abused food additives, illegal food adulterants, POPs, GMOs, food allergens and food contact material migrants. It is therefore of interest for not only analytical investigators and food safety inspectors, but also regulatory practitioners and risk assessors in various food science and research fields.

  • Stem Cell Laboratory Techniques

    A Guide for Researchers and Students
    • 1 Edición
    • Suresh Kumar Kailasa + 2 más
    • Inglés
    Stem Cell Laboratory Techniques: A Guide for Researchers and Students introduces the reader to stem cell culture, handling techniques and versatile applications used by researchers. Sections introduce stem cells, including definitions, types and basic use of stem cells in biomedical science research. The book explains laboratory procedures and techniques ranging from the extraction of stem cells from animals, cell seeding and culture, harvest and maintenance of stem cells, stem cell characterization, accurate recording, quality control, and more. In addition, it guides researchers on topics such as transcriptome analysis, proliferation study analysis, and microphysiological study. Final sections cover useful and recent applications in stem cells, such as gene editing techniques and the preparation of stem cells for in vitro study, as well as stem cell lab design and equipment used in the lab. Lastly, human and animal research ethics are discussed.

  • The Role of Gasotransmitters In the Amelioration of Arsenic Toxicity in Plants

    Biology and Biotechnology
    • 1 Edición
    • Bruno Lemos Batista + 2 más
    • Inglés
    The Role of Gasotransmitters In the Amelioration of Arsenic Toxicity in Plants: Biology and Biotechnology, in the Plant Gasotransmitter series, provides research on how gasotransmitters can reduce the stress faced by plants through arsenic contamination. With a strong focus on metabolic processes, the book presents the various pathways and mechanisms associated with gasotransmitters as part of arsenic amelioration. Initial chapters discuss the effects of arsenic on the plant genome and metabolome, as well as the mechanisms behind the uptake and translocation of arsenic in plants. The book then takes a deep dive into the role of gasotransmitters, highlighting plant physiological responses. This is an essential resource for students, researchers and agronomists interested in plant physiology, biochemistry and plant hormones.

  • New Experimental Probes for Enzyme Specificity and Mechanism

    • 1 Edición
    • Volumen 685
    • Inglés
    New Experimental Probes for Enzyme Specificity and Mechanism, Volume 685, the latest release in the Methods of Enzymology series, highlights new advances in the field with this new volume presenting interesting chapters on a variety of topics including Subverting Hedgehog Protein Autoprocessing by Chemical Induction of Paracatalysis, New Mechanistic Probes to Identify Novel Substrates for N-Myristoyltransfera... Phosphonate and α Fluorophosphonate Analogues of D Glucose 6 Phosphate as Active-Site Probes of 1L-Myo-Inositol 1 phosphate Synthase, Kinetic Mechanism of Nicotine-Degrading Enzyme Probed by Stopped-Flow Kinetic Analyses, Kinetics and Mechanism for Enzyme-Catalyzed Reactions of Substrate Pieces, and more. Additional chapters cover Kinetics and Mechanism for Reactions of Enzyme Pieces, Evaluation of allostery for the bienzyme assembly of a 3-deoxy-D-arabino heptulosonate-7-phos... synthase and chorismate mutase, Recognition and Catalysis of Reactions of Chiral Substrates by Mandelate Racemase, Innovative and emerging modalities of EGFR kinase inhibitors, Characterization of the Aminoacrylate Intermediate of Tyrosine Phenol-Lyases, and much more.

  • Microbial Inoculants

    Recent Progress and Applications
    • 1 Edición
    • Vijay Kumar Sharma + 4 más
    • Inglés
    In the recent past, beneficial microorganisms have been sustainably used in agriculture as a safe, economic, and effective alternative to chemical fertilizers or pesticides. These beneficial microbes, including bacteria, actinomycetes, and yeast, were efficiently applied in soil, seeds, fruits, or plants as inoculants, to achieve the optimum agricultural yield.An efficient delivery method or enhanced shelf life of microbial inoculants in the soil or seed is still a matter of concern. The response of local genetic or ecological factors, after microbial applications, are also unknown and less studied. Therefore, Microbial Inoculants: Recent Progress and Applications fulfills the need to explore and learn about an efficient delivery mechanism, selection of microbial strain as inoculants, and related technological advances, for the efficient and productive use of microbial inoculants. Moreover, factors like methods of formulation, interaction between host plant and microbe, impact of inoculation on the metabolomics of plants, the effect of microbial inoculants on soil dynamics, proteomics approach of plant-microbe interaction, as well as the registration and regulation process of bio inoculants for commercial production are described in 16 chapters by the leading academicians and researchers from different parts of the world.

  • Global Perspectives on the Transmission of Zoonotic RNA Viruses from Wild Animal Species to Humans

    Zoonotic, Epizootic, and Anthropogenic Viral Pathogens
    • 1 Edición
    • Jayashree Seema Nandi
    • Inglés
    Global Perspectives of the Transmission of Zoonotic RNA Viruses from Wild Animal Species to Humans: Zoonotic, Epizootic, and Anthropogenic Transmission Viral Pathogens elaborates on the current knowledge surrounding the transmission of zoonotic RNA viruses from different wild animal species to humans, including updates on the reverse transmission of pathogens to humans across the globe, with coverage of rodents, pigs, birds and primates. This reference goes beyond the phenomena occurring in African and American regions to provide further study of zoonotic pathogens from the entire world, including various parts of Asia such as India. The book comprehensively covers new knowledge on many diverse wild primate species for a global perspective on the phenomena of cross-species transmissions of pathogenic RNA viruses. Against the backdrop of the current global Covid-19 pandemic, this reference helps solve the problem of incomplete knowledge on global epidemiology of zoonotic RNA viruses. RNA viruses have pandemic, epidemic and epizootic potentials caused by Influenza viruses, Avian Influenza viruses, and other infectious viruses.

  • Advances in Accelerators and Medical Physics

    • 1 Edición
    • Toshiyuki Shirai + 2 más
    • Inglés
    Radiotherapy is now one of the major cancer treatments. The field of accelerator and medical physics is important and growing to support high precision cancer radiotherapy. Advances in Accelerators and Medical Physics provides in-depth and comprehensive coverage of the basic concepts in x-ray therapy, electron beam therapy, particle therapy, boron neutron capture therapy, and molecular imaging and therapy. Novel technologies such as FLASH therapy and laser ion accelerator are also introduced. Each section of the book presents the current state of accelerators, irradiation methods and therapy technologies, as well as future trends in advanced research. This book will serve as a key resource for researchers and students to find all information on latest cancer radiotherapy technologies and methods.

  • Alternative Methods in Neurotoxicology

    • 1 Edición
    • Volumen 9
    • Inglés
    Alternative Methods in Neurotoxicology, Volume Nine, the latest release in this series, provides an overview of important in vitro and non-vertebrate animal models available to study the neurotoxicity of a range of toxicants of occupational and environmental relevance. Chapters in this new release include Evaluation of mitochondrial function in neurotoxicology using alternative models, Planarians as a model to study neurotoxic agents, Role of Drosophila melanogaster in neurotoxicology studies: Responses to different harmful substances, Neurotoxicology of metals and metallic nanoparticles in Caenorhabditis elegans, Neurotoxicology of environmental toxicants using Caenorhabditis elegans as a model, Nauphoeta cinerea as an emerging model in neurotoxicology, and more. Other chapters cover Human Neural Stem Cells in Developmental Neurotoxicology: Current Scenario and Future Prospects, Use of Drosophila melanogaster for advances in developmental neurotoxicology studies, 3D neurospheres and neurotoxicity of organophosphorus and TCE, Genetic factors in methylmercury-induce... neurotoxicity: what we have learned from Caenorhabditis elegans models, and more.

  • Hygienic Design of Food Factories

    • 2 Edición
    • John Holah + 2 más
    • Inglés
    Advances in food safety knowledge, combined with the continuing rapid development of new food products, have had an impact on the need for improved hygiene in the food manufacturing infrastructure. This has created a need for the second edition of Hygienic Design of Food Factories, which expands all existing chapters and includes new topics, such as cold storage and the control of air in food refrigeration facilities. Additionally, chapters explore the prevention of food contamination when building during production, the risk assessment of which is becoming important globally, and hygienic building design regulations in Russia and Brazil. Divided into 6 parts, the book is now thoroughly updated and expanded. Part one reviews the implications of hygiene and construction regulation in various countries on food factory design, while taking into account retailer requirements as well. Part two describes site selection, factory layout and the associated issue of airflow. Parts three through four and five then address the hygienic design of the essential parts of a food factory. These include walls, ceilings, floors, selected utility and process support systems, entry and exit points, storage areas and changing rooms. Lastly part six covers the management of building work and factory inspection when commissioning the plant. With its distinguished editors and international team of contributors, Hygienic Design of Food Factories, 2nd edition, continues to be an essential reference for managers of food factories, food plant engineers and all those with an academic research interest in the field.

  • Effective Use of Social Media in Public Health

    • 1 Edición
    • Kavita Batra + 1 más
    • Inglés
    Effective use of Social Media in Public Health offers a well-organized and comprehensive review of social media and its impact on people’s lives and the public health sector. Divided into sections, the book addresses the growing use (and importance) of social media in conducting and disseminating research findings and covers an array of issues from cyberbullying to diversity and inclusion. Written by health educators and practitioners for health educators and practitioners, this book is a timely resource on the topics discussed.

  • Advances in Marine Biology

    • 1 Edición
    • Volumen 94
    • Jean-Francois Hamel
    • Inglés
    Advances in Marine Biology, Volume 94, the latest release in this series that highlights new advances in the field, presents interesting content written by an international board of authors. Chapters in this new release include The Falkland Islands marine ecosystem: a review of the seasonal dynamics and trophic interactions across the food web, An impact of non-native species invasions on the Caspian Sea biota, A global synthesis of microplastic contamination in wild fish species: challenges for conservation, implications for sustainability of wild fish stocks and future directions, and Addressing Underwater Noise: Joint Efforts and Progress on Its Global Governance.

  • Bioactive Lipid Mediators in Cardiopulmonary Pharmacology

    • 1 Edición
    • Volumen 97
    • Inglés
    Bioactive Lipid Mediators in Cardiopulmonary Pharmacology, Volume 97 updates readers on topics surrounding Bioactive lipid mediators. These mediators are involved in a vast array of signaling pathways that regulate both physiological and pathophysiological responses. Chapters in this new release include Cyclooxygenases and Vascular Function, Cyclooxygenases and Platelet Function, Eicosanoids and Cardiomyopathies, Cytochrome P450 Bioactive Lipids in the Heart, Epoxide Hydrolase and Leukotoxin in the Heart and Lung, Role of cytochrome P450-epoxygenase and soluble epoxide hydrolase in the regulation of vascular response, Bioactive Lipids in Hypertension, Cytochrome P450 Metabolites and Angiogenesis, 20-Hydroxyeicosatetr... Acid and Vascular Function, and more. Other critical sections cover Cytochrome P450 Eicosanoids and the Brain, Omega-3 Oxylipids, Resolvins, Lipoxins and Inflammation, Endocannabinoids as Bioactive Metabolites, and Oxylipins and Aspirin Exacerbated Respiratory Disease.

  • Sex, Gender, and Epigenetics

    From Molecule to Bedside
    • 1 Edición
    • Marianne Legato J + 2 más
    • Inglés
    Sex, Gender, and Epigenetics: From Molecule to Bedside explores our expanding knowledge of the science of epigenetics in which gene expression is modified as a consequence of small chemical additions to various components of the genome. The book provides an overview of the field, describing the epigenetic phenomena that unite biological sex and environmental experience to create the unique phenome of each individual. The book also analyzes the impact of ancestors’ environmental experience on subsequent generations through the sex-specific transmission of environmentally induced epigenetic modifications. Here, international leaders in the field discuss both sex-specific normal physiology and the experience of disease, with chapters dedicated to fetal programming, the microbiome, cancer, bipolar disorder and schizophrenia, embryogenesis, and oocyte aging, among other topics.

  • Modifications and Targeting of Protein Termini Part A

    • 1 Edición
    • Volumen 684
    • Inglés
    Modifications and Targeting of Protein Termini, Volume 684 in the Methods in Enzymology series serial highlights new advances in the field, with this new volume presenting interesting chapters pn a variety of timely topics, including Optimizing purification and activity assays of N-terminal methyltransferase complexes, In vitro reconstitution of hierarchical steps of Arg/N-degron pathway, Identification of N-degrons and N-recognins by using peptide-pull-downs combined with quantitative proteomics, A decoupled Virotrap approach to study the interactomes of N-terminal proteoforms, Monitoring ADO-dependent proteolysis in cells using fluorescent reporter proteins, Site-specific α-N-terminal methylation on peptides through chemical and enzymatic methods, and more. Additional sections cover Monitoring the interactions between N-degrons and N-recognins of the Arg/N-degron pathway, Characterization and chemical modulation of p62/SQSTM1 as an autophagic N-recognin of the Arg/N-degron pathway, Analysis of higher plant N-degron pathway components and substrates via expression in S. cerevisiae, and so much more.

  • Epigenetics in Health and Disease part B

    • 1 Edición
    • Volumen 198
    • Inglés
    Epigenetics in Health and Disease, Volume 198 in the Progress in Molecular Biology and Translational Science series, highlights new advances in the field, with this new volume presenting interesting chapters on Computational biology in epigenetics, Artificial intelligence and machine learning in epigenetics, CRISPR-dCas9 Systems for Epigenetic Editing for Therapeutic Applications, Epigenetics in heredity disease, Epigenetics in cancer development, diagnosis and therapy, Microbiota and epigenetics: health impact, Histone deacetylase (HDACs) Inhibitors: Clinical applications, Early epigenetic markers for precision medicine, Epigenetics of neurological diseases, Epigenetic Regulons in Alzheimer’s disease, and Epigenetics in epilepsy.

  • Cheminformatics, QSAR and Machine Learning Applications for Novel Drug Development

    • 1 Edición
    • Kunal Roy
    • Inglés
    Cheminformatics, QSAR and Machine Learning Applications for Novel Drug Development aims at showcasing different structure-based, ligand-based, and machine learning tools currently used in drug design. It also highlights special topics of computational drug design together with the available tools and databases. The integrated presentation of chemometrics, cheminformatics, and machine learning methods under is one of the strengths of the book.The first part of the content is devoted to establishing the foundations of the area. Here recent trends in computational modeling of drugs are presented. Other topics present in this part include QSAR in medicinal chemistry, structure-based methods, chemoinformatics and chemometric approaches, and machine learning methods in drug design. The second part focuses on methods and case studies including molecular descriptors, molecular similarity, structure-based based screening, homology modeling in protein structure predictions, molecular docking, stability of drug receptor interactions, deep learning and support vector machine in drug design. The third part of the book is dedicated to special topics, including dedicated chapters on topics ranging from de design of green pharmaceuticals to computational toxicology. The final part is dedicated to present the available tools and databases, including QSAR databases, free tools and databases in ligand and structure-based drug design, and machine learning resources for drug design. The final chapters discuss different web servers used for identification of various drug candidates.

  • Advances in Food and Nutrition Research

    • 1 Edición
    • Volumen 104
    • Fidel Toldra
    • Inglés
    Advances in Food and Nutrition Research, Volume 104 provides the latest advances on emerging bioactive compounds with putative health benefits and their controlled release and application in foods and nutraceuticals, as well as up-to-date information on food technologies, including 3D printing, safety of raw materials, and viruses in foods. Chapters in this new release cover Development and Application of Lipidomics for Food Research, Multi-omics fingerprints for food geographical origin identification and authentication, and Mass Spectrometry-based Techniques for Identification of Compounds in Milk and Meat Matrix, Micro- and Nanoencapsulation of Natural Phytochemicals: Challenges and Recent Perspectives for the Food and Nutraceuticals Industry Applications. Additional sections delve into the Effect of type and interfacial modification of emulsions on the protection and delivery of nutraceuticals, Nutricosmetics: a new frontier in bioactive peptides’ research towards skin aging, In vitro digestion models in the design of safe and nutritious foods, and Informing consumers optimally about their food: issues with and potential solutions for different types of information, their sources and consumers’ trust.

  • Advances in Yeast Biotechnology for Biofuels and Sustainability

    Value-Added Products and Environmental Remediation Applications
    • 1 Edición
    • Achlesh Daverey + 3 más
    • Inglés
    Advances in Yeast Biotechnology for Biofuels and Sustainability: Value-Added Products and Environmental Remediation Applications showcases the uses for engineered yeast in environmental applications, especially as an innovative source of biofuels. Beginning with a thorough review of recent advances and future potential for yeast biotechnology, the book proceeds to outline several options for biofuels, including lignocellulosic biofuels and alternative feedstock production through hydrolysis and alternative value-added products, including industrial acids and bioplastics and applications in agriculture and environmental remediation. Placing case studies at the center of each chapter, this book presents a future-focused perspective on the potential of yeast biotechnologies to support sustainability.

  • Artificial Intelligence in Healthcare and COVID-19

    • 1 Edición
    • Parag Chatterjee + 1 más
    • Inglés
    Artificial Intelligence in Healthcare and COVID-19 showcases theoretical concepts and implementational and research perspectives surrounding AI. The book addresses both medical and technological visions, making it even more applied. With the advent of COVID-19, it is obvious that leading universities and medical schools must include these topics and case studies in their usual courses of health informatics to keep up with the pace of technological and medical advancements. This book will also serve professors teaching courses and industry practitioners and professionals working in the R&D team of leading medical and informatics companies who want to embrace AI and eHealth to fight COVID-19. Since AI in healthcare is a comparatively new field, there exists a vacuum of literature in this field, especially when applied to COVID-19. With the area of AI in COVID-19 being quite young, students and researchers usually face a struggle to rely on the few published papers (which are obviously too specific) or whitepapers by tech-giants (which are too wide).

  • Yasargil Microneurosurgery Study Guide

    Books I, II, IIIA, IIIB, IVA, and IVB
    • 1 Edición
    • Leonard Kranzler + 1 más
    • Inglés
    Yaşargil Microneurosurgery Study Guide is designed for effective learning and study of the neurosurgical principles contained in seminal microneurosurgery textbooks. From normal microsurgical anatomy to aneurysms, arteriovenous malformations, and CNS tumor microsurgery, this study guide provides a question-and-answer format to knowledge of the background, anatomy, and techniques of microneurosurgery. This work is a practical guide to the application of microneurosurgery to a variety of brain conditions, including intracranial aneurysms, extrinsic and intrinsic tumors, while providing guidance on instrumentation and equipment, neuroanesthesia, complications, and more. This practical book is ideal for neurosurgeons, neurologists, neuroanatomists, and other technical experts with a clinical interest in brain microsurgery.

  • Formulation of Monoclonal Antibody Therapies

    From Lab to Market
    • 1 Edición
    • Amal Ali Elkordy
    • Inglés
    Formulation of Monoclonal Antibody Therapies: From Lab to Market covers a wide range of topics about therapeutic monoclonal antibodies (mAbs) with a focus on formulation aspects. Therapeutic monoclonal antibodies are used for treatment of chronic diseases. It brings together a comprehensive knowledge in one accessible volume. Starting with foundational information on monoclonal antibodies, the book then discusses the importance of biopharmaceutical products, monoclonal antibodies, and biosimilars in treatment of chronic diseases, pharmaceutical aspects of mAbs, and how it can be administered. It also covers the industrial point of view and the clinical application of mAbs including in oncology, general medicine, rheumatology, hematology, dermatology, gastrointestinal tract, metabolic diseases, and dentistry. Formulation of Monoclonal Antibody Therapies: From Lab to Market is essential reading for researchers in biotechnology and biopharmaceutical fields, academics and pharmaceutical industrial scientists, and university students in pharmaceutical and biopharmaceutical sciences.

  • Colorectal Disorders and Diseases

    An Infographic Guide
    • 1 Edición
    • Constantine P. Spanos
    • Inglés
    Colorectal Disorders and Diseases: An Infographic Guide provides a comprehensive and up-to-date overview of the most relevant diagnostic modalities, staging, classification systems and current therapeutic modalities for colorectal disorders and diseases. With coverage from incontinence, prolapse, anal fissures, and cancer, this reference offers a wide-ranging guide to colorectal disorders and diseases. The use of engaging infographics throughout provides an inviting “at-a-glace” perspective of the subject, allowing users to retain a large amount of information without the need to scroll through large text or complex algorithms. This is an important reference for clinicians, surgeons and medical students rotating in colorectal surgery as well as scientists that need a quick reference for research of colorectal issues including epidemiology, diagnosis and therapy.

  • Precision Agriculture

    Evolution, Insights and Emerging Trends
    • 1 Edición
    • Qamar Zaman
    • Inglés
    Precision Agriculture: Evolution, Insights and Emerging Trends presents a complete guide from foundational concepts to the economic, commercial and environmental implications of the approach. Showcasing recent research improvements, future trends, and highlighting innovative use of machine vision, artificial intelligence, UAVs, drones, IoT and data analytics to promote sustainable agriculture, the book brings the reader up-to-date with understanding and implementing this targeted practice. From the basic elements of agronomy to insights on reflectance and remote sensing indices, chapters use summary abstracts, case studies and real-world examples of implementing the tools of precision agriculture (PA) to demonstrate the latest advances. It includes explanations on the origin of the intra-plot variability of a culture (spatial and temporal), different types of existing sensors, controllers and site-specific management. The book further explores yield monitoring, weed, disease and pest control, automated irrigation systems, PA tools for variable rate application of inputs within the field, and data processing methods. By also exploring the economic profitability of precision farming approaches, and its utility for sustainable agriculture, Precision Agriculture: Evolution, Insights and Emerging Trends is a truly comprehensive view of this important approach to improving global agriculture production. Scientists, researchers, policymakers, graduate and postgraduate students, and engineers in the related fields of agriculture, computer science and engineering will benefit from this book.

  • Overcoming Obstacles in Drug Discovery and Development

    Surmounting the Insurmountable—Case Studies for Critical Thinking
    • 1 Edición
    • Kan He + 2 más
    • Inglés
    Overcoming Obstacles in Drug Discovery and Development uses real-world case studies to illustrate how critical thinking and problem solving skills are applied in the discovery and development of drugs. It also shows how developing critical thinking to overcome issues plays an essential role in the process. Modern drug discovery and development is a highly complex undertaking that requires scientific and professional expertise to be successful. After the identification of a molecular entity for treating a medical condition, challenges inevitably arise during the subsequent development to understand and characterize the biological profile; feedback from scientists is used to fine-tune the molecular entity to obtain an effective and safe product. In this process, the discovery team may identify unexpected safety issues and new medical disorders for treatment by the molecular entity. Invariably inherent in this complex undertaking are miscues, mistakes, and unexpected problems that can derail development and throw timetables into disarray, potentially leading to failure in the development of a medically useful drug. Addressing critical unexpected problems during development often requires scientists to utilize critical thinking and imaginative problem-solving skills. Overcoming Obstacles in Drug Discovery and Development will be essential to young scientists to help learn the skills to successfully face challenges, learn from mistakes, and further develop critical thinking skills. It will also be beneficial to experienced researchers who can learn from the case studies of successful and unsuccessful drug development.

  • The Science of Glaucoma Management

    From Translational Research to Next-Generation Clinical Practice
    • 1 Edición
    • Kevin Gillmann + 1 más
    • Inglés
    The Science of Glaucoma Management: From Translational Research to Next-Generation Clinical Practice bridges the gap between laboratory research and clinicians by bringing the latest promising research directly from researchers to clinicians long before they translate into clinical advances, and often before they are presented at conferences. Organized as a series of clinically relevant topics written by world-leading experts, this book summarizes the current state of laboratory and translational research and draws on the potential implications for day-to-day clinical practice. It offers new insights and mind-opening statements through contributions from some of the most respected glaucoma research groups. The book allows glaucoma specialists to explore novel ways to refine and rethink their practice based on the latest discoveries in basic sciences and breakthrough technologies, and to gain a better understanding on how their specialty is evolving and how research may shape tomorrow’s practice.

  • Advanced Microbial Technology for Sustainable Agriculture and Environment

    • 1 Edición
    • Saurabh Gangola + 3 más
    • Inglés
    Advanced Microbial Technology for Sustainable Agriculture and Environment focuses on plant-microbe interactions in respect to bioremediation and plant growth promotion, providing insights on diverse approaches such as genomics, metagenomics, proteomics, bioinformatics and other high-throughput analyses of environmentally relevant microorganisms. The impact of frequent applications of potentially toxic chemicals (pesticides and fertilizers) and increased industrialization processes on microbial diversity emphasizes the potential threat to microbial biodiversity in ecosystems. This is an ideal resource on current trends and the future of PGPR developments with bioremediation potential.Moreover, it gives a deep understanding of the genetics of microbial biodegradation and different remediation mechanisms that help to re-establish the natural environment.

  • Food, Gastronomy, Sustainability, and Social and Cultural Development

    Cross-Disciplinary Perspectives
    • 1 Edición
    • F. Xavier Medina + 2 más
    • Inglés
    Food, Gastronomy, Sustainability, and Social and Cultural Development analyzes the relationship between gastronomy and sustainability from a sociocultural perspective. It uses practical case studies to reveal the connection between food, society, culture, and the impact they have with each other. Beginning with the introduction of the relationship among gastronomy, sustainability, culture, and contemporary controversies, this book expands topics from binomial gastronomy at local level, impact of sustainability on gastronomic experiences, an evaluation of production systems to the role of gastronomy, and sustainability in tourism. The role of technology in food and sustainability, health, ideologies, and social movements surrounding gastronomy are also widely discussed. This book is a valuable reference for food scientists, undergraduate and graduate students, and industrial professionals working in the food processing field.

  • New Insights into Glioblastoma

    Diagnosis, Therapeutics and Theranostics
    • 1 Edición
    • Carla Vitorino + 2 más
    • Inglés
    New Insights into Glioblastoma: Diagnosis, Therapeutics and Theranostics provides a compendium of recent diagnostic and therapeutic advances in GBM, encompassing a pipeline of compounds and (bio) nanotechnology strategies that have stood out with potential increased antitumoral activity and capability to cross the blood-brain barrier. Issues and challenges related to their translation into the clinical practice and their contribution to the increase in survival rates and well-being of patients are addressed. This is a valuable resource for graduate students, oncologists, cancer researchers and members of the biomedical field who need to learn more on recent developments on the management of glioblastoma. The book is split in three parts: Diagnosis, focusing on biomarkers and techniques such PET/MRI, infrared thermography, and deep neural networks; Therapeutics, discussing new chemical entities, as natural products and repurposed drugs, and new formulation approaches, as nanotechnology-based and microRNA approaches; and Theranostics, explaining the role of omics, system-based approaches, and glioblastoma microenvironment.

  • Anesthesia and Analgesia in Laboratory Animals

    • 3 Edición
    • Melissa Dyson + 4 más
    • Inglés
    Anesthesia and Analgesia in Laboratory Animals focuses on the special anesthetic, analgesic and postoperative care requirements associated with experimental interventions. Fully revised and updated, this new edition provides the reader with agents, methods and techniques for anesthesia and analgesia that ensure humane, reproducible, and successful procedural outcomes. Sections cover ethical, regulatory and scientific considerations, principles of anesthesia and analgesia, anesthetic equipment and monitoring, periprocedural care, including dedicated chapters to the assessment and management of pain in laboratory species, and practical considerations by species, including relevant anatomy, physiology, and behavior of a broad range of lab animal species. This will be a complete reference for veterinarians involved in lab animal research as well as senior graduate, graduate students, post-docs and researchers who utilize animals in biomedical research.

  • Microbiome Therapeutics

    Personalized Therapy Beyond Conventional Approaches
    • 1 Edición
    • Nar Singh Chauhan + 1 más
    • Inglés
    Microbiome Therapeutics: Personalized Therapy Beyond Conventional Approaches addresses the current knowledge and landscape of microbiome therapeutics, providing an overview of existing applications in health and disease as well as potential future directions of microbiome modulations and subsequent translation to the global industry and market. This important reference provides the most current status of microbiome therapeutics as well as possible future perspectives through coverage of topics including the application of microbiome therapeutics; various additive, subtractive and modulatory approaches; microbiome composition of health and diseases, insights into live bio-therapeutics and the clinical data supporting their efficacy. Case studies are provided throughout the book to further define, describe and evaluate microbiome therapeutics success and failure.

  • Williams' Essentials of Nutrition and Diet Therapy

    • 13 Edición
    • Joyce Ann Gilbert + 1 más
    • Inglés
    **American Journal of Nursing (AJN) Book of the Year Awards, 3rd Place in Adult Primary Care, 2024****Selected for Doody’s Core Titles® 2024 with "Essential Purchase" designation in Nutrition**Master the essentials of nutrition science and patient care with this concise text! Williams’ Essentials of Nutrition and Diet Therapy, 13th Edition helps you understand and apply nutrition concepts in the treatment of disease, disease prevention, and life enhancement. The text is broken out into three parts: the basics of nutrients and the body, the life cycle and community nutrition, and clinical nutrition. Case studies help you determine nutritional interventions in treating both acute and chronic conditions. Written by nutrition specialists Joyce Gilbert and Eleanor D. Schlenker, this book includes the latest advances in research and evidence-based practice.

  • Biomedical Engineering of Pancreatic, Pulmonary, and Renal Systems, and Applications to Medicine

    • 1 Edición
    • Dhanjoo N. Ghista
    • Inglés
    Biomedical Engineering Modeling of Pancreatic, Respiratory, and Renal Regulatory Systems, and their Medical Assessments addresses the need for biomedical engineering to provide physiological analysis of organ systems and their medical applications to help enable quantitative formulation of physiological systems and defining their functions and dysfunctions, leading to precision diagnostics of diabetes, lung diseases, and kidney failure, often in the form of non-dimensional indices. The book chapters also deal with treatment systems, namely automated insulin infusion systems, hemodialysis, and peritoneal dialysis. The book is formulated to solve many physiological, bioengineering, and medical problems.

  • Biología celular biomédica

    • 2 Edición
    • Alfonso Calvo González
    • Español
    Nueva edición del texto magníficamente dirigido por el Dr. Alfonso Calvo en el que se aborda la temática de la biología celular biomédica haciendo especial énfasis en las patologías causadas por alteraciones celulares. En la obra ha participado un nutrido grupo de colaboradores tanto españoles como mexicanos y argentinos. Cada uno de ellos expertos en diferentes campos, desde la Biología celular, la Patología , Oncología y otras especialidades clínicas que aportan sus conocimientos y perspectivas para poder tener como resultado un texto integrado y actualizado. Se recogen los aspectos más novedosos de las temáticas más punteras en el campo de labiología celular, tales como las células madre, la terapia celular, la regeneración y la bioingeniería de tejidos, así como el posible desarrollo de órganos en el laboratorio La obra cuenta con un extenso material complementario disponible online a través de la plataforma de SC.es en la que se encuentra casos clínicos, presentaciones ppt, problemas y actividades practicas, preguntas de autoevaluación y videos.

  • Sustainable Food Science

    A Comprehensive Approach
    • 1 Edición
    • Pasquale Ferranti
    • Inglés
    Sustainable Food Science: A Comprehensive Approach provides a timely resource on new materials and ingredients currently available in the food industry, along with cutting-edge research on how to develop and secure sustainable food for a growing world population. With contributions from international experts and an outstanding editing team, the book covers sustainable sources of ingredients for the food industry, i.e., pulses, soybeans, peanuts, along with prospective and emerging sources such as industrial hemp, insects, algae, etc. In addition, other sections cover sustainable processes for new food sources and new food design, such as microbiological and biotechnological processes and dairy and meat substitutes. Users will value the clear-cut, in-depth and expert assessment of each topic and appreciate its sensible and logical hierarchical structure. This reference work will provide expert guidance for food scientists of all levels – both in academia or industry.

  • Clinical Neuroepidemiology of Acute and Chronic Disorders

    • 1 Edición
    • Jahangir Moini + 2 más
    • Inglés
    Clinical Neuroepidemiology of Acute and Chronic Disorders explores the epidemiology of disorders that affect the nervous system, providing comprehensive discussions on incidence, prevalence, and more. With thorough coverage of a variety of disorders, chapters detail etiology, risk factors, pathophysiology, clinical manifestations, diagnosis, global incidence and prevalence, age-specific incidence, global mortality, prevention, treatment and prognosis for each disorder. Chapters uniquely discuss the effects of the COVID-19 coronavirus upon the nervous system and in relation to several diseases, including new discoveries and treatments for Alzheimer’s disease and migraine headaches. Real-world case studies with critical thinking questions and "Focus On" boxes highlight important information.

  • Digital Transformation in Healthcare in Post-COVID-19 Times

    • 1 Edición
    • Miltiadis Lytras + 2 más
    • Inglés
    Digital Transformation in Healthcare in Post-Covid19 Times discusses recent advances in patient care and offers critical comparative insights into their application across multiple domains in healthcare. By showcasing key problems, best practices and emerging challenges, the book offers a state-of-art review of opportunities and prospects in the process of delivering smart sustainable healthcare services. Topics discussed include healthcare challenges in the post-COVID-19 era, enabling technologies for digital transformation, value driven approaches to the delivery of patient centric top-quality health services, and analytics and enhanced decision making. In addition, the book updates knowledge on best practices for training towards digital transformation and sustainable health. This is a valuable resource for healthcare professionals, medical doctors, researchers, graduate students and members of the biomedical field who are interested in learning more about the use of emerging technologies in healthcare.

  • Environmental Threats to Pollinator Health and Fitness

    • 1 Edición
    • Volumen 64
    • Jon Harrison
    • Inglés
    Environmental Threats to Pollinator Health and Fitness, Volume 64 in the Advances in Insect Physiology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics, including The threat of higher temperatures to pollinating insects, The challenge of balancing fungicide use and pollinator health, Insecticide effects on pollinating insects, Effects of invasive pathogens and parasites on pollinating insects, Heavy metal pollutants: the hidden pervasive threat to honey bees and other pollinators, Honey bee nutritional ecology: from physiology to landscapes, and more.

  • Neuroglia: Function and Pathology

    • 1 Edición
    • Alexei Verkhratsky + 1 más
    • Inglés
    Diverse specialised neuroglial cells guarantee the development, preservation, and health of the central nervous system, the peripheral nervous system, the enteric nervous system, and the special senses. In the central nervous system, it is the astrocytes, oligodendrocytes, and microglia that safeguard nerve cell function and integrity that controls all behaviours and encompasses the cerebral cortex of the brain which is the root of humanity. In the peripheral nervous system, Schwann cells play the leading role, together with satellite glial cells of the sensory and autonomic ganglia, ensuring correct communication between the organs and tissues with the brain and the spinal cord. In the enteric nervous system, specialised enteric glial cells maintain all aspects of gastrointestinal function. Then there are distinctive glial cells of the special senses that ensure how the body perceives and reacts to its environment. In pathology, neuroglia strive to protect the diverse cellular components of the nervous system and are responsible for a proactive programme of posttraumatic restructuring that is aimed at recovery of life-sustaining function. Neuroglia: Function and Pathology provides a highly original and comprehensive account of the physiology and pathophysiology of glial cells in the central and peripheral nervous systems. The first part of the book provides a far-reaching description of glial cell form and function, from their evolution in invertebrates to their complexity in humans, encompassing the developmental origin of the varied glial cell types and their diversity of morphology, molecular biology and cellular physiology. The second part of the book is devoted to an all-embracing evaluation of glial cell pathophysiology, commencing with definitive explanations of the fundamental pathologies of the main glial cell types, and ending in a systematic examination of glial contributions to specific neurological diseases. This book emphasises the central roles played by the different classes of neuroglial cells in the progression and outcome of neurological disorders of the central and peripheral nervous systems and highlights potential of glial cells as therapeutic targets. The book contains more than 2500 key references from over 150 years of glial research and is superbly illustrated with over 350 original and explanatory full colour figures that describe the diverse characteristics and properties of glial cells in health and disease. Under the same cover, this book combines an authoritative reference book for research and clinical neuroscientists and at the same time serves as an instructive textbook for students of neuroscience, from undergraduates to postgraduates.

  • Mesenchymal Stem Cells

    Biological Concepts, Current Advances, Opportunities and Challenges
    • 1 Edición
    • Leisheng Zhang + 4 más
    • Inglés
    Mesenchymal Stem Cells: Biological Concepts, Current Advances, Opportunities and Challenges systematically summarizes and discusses the basic concepts and latest updates of mesenchymal stem cells (MSCs) in the past 60 years, as well as the latest progress of clinical translational research and regulatory policy at home and abroad, which will be of great practical significance for promoting and guiding the future development of stem cell production and regenerative medicine.

  • The Impact of Nanoparticles on Agriculture and Soil

    • 1 Edición
    • Nar Singh Chauhan + 1 más
    • Inglés
    The Impact of Nanoparticles on Agriculture and Soil, part of the Nanomaterials-Plant Interaction series, contributes the most recent insights into understanding the cellular interactions of nanoparticles in an agricultural setting, focusing on current applications and means of evaluating future prospects. In order to ensure and improve the biosafety of nanoparticles, it is a primary concern to understand cellular bioprocess like nanomaterial’s cellular uptake and their influence on cellular structural, functional and genetic components. This book addresses these and other important aspects in detail along with showcasing their applications in the area of agriculture. With an international team of authors, and experienced editors, this book will be valuable to those working to understand and advance nanoscience to benefit agricultural production and human and environmental welfare. In-depth knowledge of these bioprocess will enable researchers to engineer nanomaterials for enhanced biosafety.

  • Advances in Virus Research

    • 1 Edición
    • Volumen 115
    • Margaret Kielian + 1 más
    • Inglés
    Advances in Virus Research, Volume 115, the latest release in this comprehensive serial that highlights new advances in the field, includes updates on a variety of timely topics, including Plant viral nanotools, Mycoviruses, Rift Valley Fever virus entry and infection, and more.

  • Neuropsychopharmacology

    • 1 Edición
    • Jahangir Moini + 2 más
    • Inglés
    Neuropsychopharmacol... reviews the principles of pharmacology with a focus on the central nervous system and autonomic nervous system. Beyond autonomic and central nervous system pharmacology, this volume uniquely discusses psychiatric disorders and the pharmacological interventions that are available for conditions including depression, schizophrenia and anxiety disorders. With a focus on these specific body systems, readers will see end-of-chapter questions that offer real-world case studies, as well as multiple-choice questions for further learning. Beneficial features and content also include two extensive examination tests, which each contain 100 questions for better learning or to be used in teaching, and a glossary. Helpful appendices cover high-alert medications and toxicology effects on the nervous system. Each chapter will contain classifications of medications, pharmacokinetics, mechanism of action, clinical indications and toxicities.

  • MicroRNA in Regenerative Medicine

    • 2 Edición
    • Chandan K. Sen
    • Inglés
    Regulating virtually all biological processes, the genome’s 2,654 newly discovered variants of mature microRNAs – short ribonucleic acid molecules found in eukaryotic cells – hold a key role in the body’s toolkit of regenerative and reparative capacities. Identifying how to activate and deliver these specialist molecules may aid in the repair and regeneration of major tissue and organ damage in future therapies. In MicroRNA and Regenerative Medicine, Second Edition, over 50 leading experts address foundational and emerging topics in the field. Concisely summarizing and evaluating key findings from new research and their translational application, contributors examine current and future significance of clinical research in the miRNA area. Coverage encompasses all major aspects of fundamental stem cell and developmental biology, including the uses of miRNA in cell and tissue plasticity, developmental biology, tissue repair, and regeneration. In particular, contributors provide focused coverage of methodologies for regenerative intervention and tissue engineering. Topics new to this edition include proteomic changes during tissue repair and regeneration, horizontal transfer of miRNAs in tissue regeneration, tissue stemness, peripheral nerve regeneration, miRNA as biomarkers, microRNA in pregnancy and embryo development, exogenous and diet derived microRNA in tissue development, ocular microRNA, mitochondrial microRNA, sensory hair cell death and regeneration, and microRNA in senescence.

  • Neuro-Urology Research

    A Comprehensive Overview
    • 1 Edición
    • Anne M.J. Verstegen
    • Inglés
    **Selected for Doody’s Core Titles® 2024 in Urology**Neuro-Urolo... Research: A Comprehensive Overview describes the current status of the neuro-urology field including the latest discoveries, explains in detail some of the neuroscience tools that can be used when studying the neural control of the lower urinary tract, and discusses potential future directions for research. The first section, Neuroscience in Urology Research, reviews neuro-regulators and the important anatomical brain sites. It also provides an overview of voluntary versus reflex micturition control and describes how bladder physiology readout is a useful tool in research. The second section, Fundamental and Translational Neuro-Urology Research, discusses the translational potential of basic research for patients and the impact of neuro-urology research on clinical practice. Chapters in this section provide more insight into pathologies endemic to specific patient populations and areas for treatment development opportunities. The third section, Neurobiological Tools Applied to Neuro-Urology Research, supplements the ‘A Quick Guide to the "Neuroscience Toolbox"’ and introduces research techniques such as RNA sequencing and calcium imaging of neural activity. The fourth and final section, aptly titled Research Directions and Research Opportunities, covers research directions that remain underexplored or have high therapeutic potential. Research in neuro-urology presents a route to understanding how bladder function is controlled and how urinary continence is maintained. This book provides a platform for researchers to initiate collaborations on the many underexplored research topics and to consolidate knowledge, ultimately lending itself to a coordinated and multi-center research approach that will benefit the field.

  • Drying Technology in Food Processing

    Unit Operations and Processing Equipment in the Food Industry
    • 1 Edición
    • Seid Mahdi Jafari + 1 más
    • Inglés
    Drying Technology in Food Processing, in the Unit Operations and Processing Equipment in the Food Industry series, explains the processing operations and equipment necessary for drying of different food products. These processes and unit operations are very important in terms of qualitative properties and energy usage. Divided into four sections, "Drying basics", "Different dryers in the food industry", "Application of drying in the food industry", and "Design, control, and efficiency of dryers", all chapters emphasize experimental, theoretical, computational and/or applications of food engineering principles and the relevant processing equipment. Written by experts in the field of food engineering, in a simple and dynamic way, this book targets industrial engineers working in the field of food processing and within food factories to make them more familiar with drying unit operations.

  • Varieties and Landraces

    Cultural Practices and Traditional Uses
    • 1 Edición
    • Marney Pascoli Cereda + 1 más
    • Inglés
    Varieties and Landraces: Cultural Practices and Traditional Uses, Volume Two in the Underground Starchy Crops of South American Origin series, brings information on the applied level of producing and using starch from a range of plants grown in tropical and subtropical areas of South American origin. The book presents the economic and social importance of these crops that store starch in underground organs. The title also explores bioactive compounds as a way for the valorization of these crops, along with commercial and traditional cultivation in South America (Colombia/Venezuela/... highlands, Mexico, Brazilian savannah and Pantanal, besides the Amazon forest), bringing botanical information, too. Edited by a team of experts with a solid background in starch extraction research, this book is ideal for anyone involved in research and development, as well as anyone in cultivation, quality control and legislation in the field of starch.

  • Glycoside Hydrolases

    Biochemistry, Biophysics, and Biotechnology
    • 1 Edición
    • Arun Goyal + 1 más
    • Inglés
    Glycoside Hydrolases provides a detailed overview of the biochemical, biophysical, and protein engineering properties of glycoside hydrolases, a class of enzymes in growing use across various applications. Here, more than a dozen global experts discuss the structural and catalytic mechanisms of specific glycoside hydrolases, followed by their implications in biotechnological applications of different industrial sectors such as the food and feed industry, paper and pulp industry, the bioenergy sector and the pharmaceutical industry. Authors consider how the application of glycoside hydrolases may boost industrial production of valued products, and the broader environmental and sustainability goals of converting agrowaste into valued products. This book helps researchers and students across industry and academia gain deep knowledge of glycoside hydrolases, to advance new experimental research and applications from biofuel to drug discovery.

  • Epigenetic Cancer Therapy

    • 2 Edición
    • Steven Gray
    • Inglés
    Epigenetic Cancer Therapy, Second Edition provides a comprehensive discussion of healthy and aberrant epigenetic biology, along with new discoveries to improve our understanding of cancer epigenetics and therapeutics. The book encompasses large-scale intergovernmental initiatives, as well as recent findings across cancer stem cells, rational drug design, clinical trials, and chemopreventative strategies. As a whole, the work articulates and raises the profile of epigenetics as a therapeutic option in the future management of cancer. Since the publication of the first edition of this book, the field of epigenetics has undergone significant change. New epigenetic therapies have been designed and approved for clinical use. Our knowledge of the plasticity of the epigenome in cancer and disease has expanded dramatically, with increasing evidence linking pollution to epigenetic changes in cancer development. This second edition has been fully updated to address these changes, along with promising therapeutic programs such as CRISPR/Cas9 mediated approaches, CAR-T based therapies, epigenetic priming, histone modifications, and similar, transformative advances across synthetic biology and cellular engineering.

  • The Role of Growth Regulators and Phytohormones in Overcoming Environmental Stress

    • 1 Edición
    • Anket Sharma + 4 más
    • Inglés
    The Role of Growth Regulators and Phytohormones in Overcoming Environmental Stress is a comprehensive resource on all major PGRs. These include auxins, cytokinins, jasmonates, polyammines, plant growth promoting rhizobacteria (PGPR), and more. In the last two decades, researchers have explored a lot about the roles of plant growth regulators (PGRs) in boosting the resistance of plants under stress conditions. These PGRs acts as stimulators for various physiological processes by regulating key cell signaling pathways. This title is an essential read for any scientist wanting to understand the latest advances in combatting abiotic stresses using plant growth regulators.In the present era, plants are facing a lot of challenges during their lifecycle, including growth declines due to abiotic stress. The main abiotic stresses threatening plants are water scarcity, salinity, extreme temperatures, heavy metals and pesticides. These stresses directly or indirectly cause toxicity to plants, causing hindrance to their growth and development, and ultimately reduce plant productivity.

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