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Elsevier

Libros en Ciencias de la Vida

  • Economic Evaluation in Genomic and Precision Medicine

    • 1 Edición
    • Inglés
    Economic Evaluation in Genomic and Precision Medicine provides an in-depth examination of essential concepts, protocols and applications of economic evaluation in genomic and precision medicine. Contributions from leading international medical geneticists and health economists compile new ways to effectively assess the costs and outcomes of different genomic care pathways, implement cost-effective medical interventions, and enhance the value of genomic and precision healthcare. Foundational chapters and discipline-specific case studies cover topics ranging from the economic analysis of genomic trial design, to health technology assessment of next-generation sequencing, ethical aspects, economic policy in genomic medicine, and pricing and reimbursement in clinical genomics.

  • Agricultural Soil Sustainability and Carbon Management

    • 1 Edición
    • Sunita Kumari Meena + 6 más
    • Inglés
    Agricultural Soil Sustainability and Carbon Management presents long-term research in the field of sustainable soil use and management to guide in the prioritizing the multifunctional value of soil health and addressing interdisciplinary links between major issues such as biodiversity and climate change. As soil is the largest terrestrial carbon pool and a significant contributor of greenhouse gases, much progress can be made toward curtailing the climate crisis by sustainable soil management practices. The book provides valuable insight into the soil and carbon management, research gaps, and the methodological challenges for research into soil carbon management that will be important over the decades.

  • Athymic Nude Rat Brain Atlas

    • 1 Edición
    • Bengt Mattsson + 2 más
    • Inglés
    Athymic Nude Rat Brain Atlas will provide the first stereotaxic brain atlas of the athymic nude rat (Crl:NIH-Foxn1rnu), a T-cell deficient rat model commonly used in experimental studies and pre-clinical safety and efficacy studies. This 2D vector-based atlas contains coronal, sagittal, and horizontal brain sections of an athymic rat brain rendered from a single cleared specimen, placed in a computerized 3D environment. The maps enable readers to better calculate co-ordinates to target specific structures for toxin, virus, or cell delivery using stereotaxic surgery. This atlas will be a valuable resource for any neuroscientist who wishes to work with nude rats in experimental and pre-clinical studies.

  • Atlas of Operative Techniques in Gender Affirmation Surgery

    • 1 Edición
    • Rajveer S. Purohit + 1 más
    • Inglés
    As transgender and gender non-binary individuals are a growing demographic, the number of patients seeking gender confirmation surgery is increasing. Atlas of Operative Techniques in Gender Affirmation Surgery is a highly illustrated and practical guide to the different types of gender affirmation surgery. Top and bottom surgeries are illustrated include facial feminization, mastectomy, techniques in phalloplasty, metoidioplasty, different approaches to vaginoplasty, management of complications of gender affirming surgery, and more.This comprehensive textbook is a must-have guide for individuals interested in gender affirmation surgery to master the complex operative procedures that this field demands and to refine their techniques.

  • Medicines for Cancer

    Mechanism of Action and Clinical Pharmacology of Chemo, Hormonal, Targeted, and Immunotherapies
    • 1 Edición
    • Surya K. De
    • Inglés
    Medicines for Cancer: Mechanism of Action and Clinical Pharmacology of Chemo, Hormonal, Targeted, and Immunotherapies covers most known anti-cancer therapeutics. Cancer is the second leading cause of death worldwide, with its various forms resulting in nearly one out of every six mortalities each year. This book describes all US FDA-approved drugs (up to 2021), such as small molecules, peptides, monoclonal antibodies, whole antibodies, gene therapy, antibody-drug conjugates, cell therapy, and immunotherapies, along with information on their generic and brand names, medical uses, details dosage, mechanisms of actions, pharmacokinetics and side effects. Chemical structures of small molecules, small peptides, antibody-drug conjugates are also provided. This book is ideal for medicinal chemists, oncologists, and pharmacologists, but it will also be indispensable for professional researchers, whether they are working in the clinic or the pharmaceutical industry.

  • New Horizons in Natural Compound Research

    • 1 Edición
    • Surya Nandan Meena + 3 más
    • Inglés
    New Horizons in Natural Compound Research provides the latest updates in natural compound research (plant, microbes, algae, fungi) and their novel applications in health, agriculture and environment. The book gives recent advances in the extraction of natural compounds, cutting-edge approaches for natural compound purifications, and emerging trends in natural compound screening and identification. In addition, it provides a detailed explanation of the databases and libraries of natural compounds, as well as their significance. Sections focus on research and multidisciplinary practical techniques of natural product research, encouraging young scientists to pursue unique research while also generating strong research ideas. From a future perspective, this book acts as a guide to identify potential areas and new research opportunities in the field of natural products and their service towards human beings, animals and the environment.

  • Rang & Dale's Pharmacology

    • 10 Edición
    • James M. Ritter + 6 más
    • Inglés
    **Selected for 2026 Doody's Core Titles in Pharmacology**Rang and Dale’s Pharmacology is internationally acknowledged as the core textbook for students of pharmacology, and has provided accessible, up-to-date information on drugs and their mechanism of action for more than 30 years.Now in its tenth edition, it has been updated to include important new drugs such as gene therapies, personalised medicines and the new wave of RNA drugs. However it has not lost any of the elements that have contributed to its popularity, such as color coding and illustrations, making it reader-friendly while comprehensively covering the depth of detail required.This essential book is recommended as the first-choice undergraduate text for science and medical students and junior doctors and will also be useful for students in other professional disciplines such as pharmacy, veterinary medicine and nursing.

  • Plant-Microbe Interaction - Recent Advances in Molecular and Biochemical Approaches

    Volume 1: Overview of Biochemical and Physiological Alteration During Plant-Microbe Interaction
    • 1 Edición
    • Prashant Swapnil + 5 más
    • Inglés
    Plant-Microbe Interaction - Recent Advances in Molecular and Biochemical Approaches: Overview of Biochemical and Physiological Alteration During Plant-Microbe Interaction, Volume One covers the role of these plant microbes and their interaction between plants and microbes. These beneficial microbes, such as bacteria and fungi are also known as plant growth-promoting rhizobacteria (PGPR) through a biochemical reaction that may improve induced systemic resistance in the plant host via indirectly (against phytopathogens) or directly (the solubilization of mineral nutrients) by producing phytohormones and specific enzymes such as 1-aminocyclopropane-... deaminase. The book covers biochemical processes such as physiological, metabolic, etc. of plant and microbe interactions, the biochemistry of biological systems, the interaction of biological systems above-ground or within the rhizosphere, and the history of growth promoting microbiomes, their roles in phytoremediation efficiency, physiological and biochemical studies, chemical communication and signaling mechanisms.

  • Plant-Microbe Interaction - Recent Advances in Molecular and Biochemical Approaches

    Volume 2: Agricultural Aspects of Microbiome Leading to Plant Defence
    • 1 Edición
    • Prashant Swapnil + 5 más
    • Inglés
    Plant-Microbe Interaction - Recent Advances in Molecular and Biochemical Approaches: Agricultural Aspects of Microbiome Leading to Plant Defence, Volume Two continues the work of Volume One, covering the role of these plant microbes and their interaction between plants and microbes. These beneficial microbes, such as bacteria and fungi are also known as plant growth-promoting rhizobacteria (PGPR) through a biochemical reaction that may improve induced systemic resistance in the plant host via indirectly (against phytopathogens) or directly (the solubilization of mineral nutrients) by producing phytohormones and specific enzymes such as 1-aminocyclopropane-... deaminase. The book covers biochemical processes such as physiological, metabolic, etc. of plant and microbe interactions, the biochemistry of biological systems, the interaction of biological systems above-ground or within the rhizosphere, and the history of growth promoting microbiomes, their roles in phytoremediation efficiency, physiological and biochemical studies, chemical communication and signaling mechanisms.

  • COVID-19 in Alzheimer's Disease and Dementia

    • 1 Edición
    • P. Hemachandra Reddy + 1 más
    • Inglés
    COVID-19 in Alzheimer’s Disease and Dementia crucially summarizes the current status of the coronavirus in patients suffering from these conditions, describing why they are a common cause of morbidity among those with COVID-19. The first section includes chapters that provide a general description of COVID-19, including SARS-CoV-2 structure, function, and biology, and its impact on the elderly with chronic conditions include hypertension, diabetes, obesity, kidney disease, respiratory illnesses, and infectious diseases. Also discussed are effects of the virus on the immune system. The second section shifts to the impact of COVID-19 on those with dementia or Alzheimer’s disease, with special emphasis on age, gender, ethnic background, and lifestyle. Bringing this focus on neurodegenerative disease in one comprehensive resource, this volume is an essential reference for neuroscientists, clinicians, biomedical scientists, and all others working or interested in the field.

  • Plant Small RNA in Food Crops

    • 1 Edición
    • Praveen Guleria + 2 más
    • Inglés
    Plant Small RNA for Food Crops provides foundational insights into the role of small RNA in food crops in varying environmental conditions and how it can help in developing molecular frameworks to support agricultural sustainability to feed the world’s population. Small RNA populations have been widely identified in various plants and have been reported to be involved in regulating the molecular functioning of plants and their responses for biotic and abiotic environmental factors. Until now, however, a detailed compilation of role of small RNAs in food crops growth, yield and environmental responses had been unavailable. This book provides a detailed description of role of various small RNAs whose utilization in a range of food crops may serve to improve sustainability, productivity, and maintenance during environmental stress conditions. It brings together the reported small RNAs along with their applications specific to food crops, but also covers recent studies, innovations and future perspectives.

  • Advances in Agronomy

    • 1 Edición
    • Volumen 179
    • Donald L. Sparks
    • Inglés
    Advances in Agronomy, Volume 179, the latest release in this leading reference on agronomy, contains a variety of updates and highlights new advances in the field. Chapters in this new release include Complementing Compost with Biochar for Agriculture, Soil Remediation and Climate Mitigation, Weed Management in Wet Direct-seeded Rice (Oryza sativa L.): Issues and Opportunities, Plant Temperature Response and Heat Tolerance in Rice: A Review, Obstacles in Continuous Cropping: Mechanisms and Control Measures, Agriculture-Related Green House Gas Emissions and Mitigation Measures, and more.

  • Sustainable Agriculture and the Environment

    • 1 Edición
    • Muhammad Farooq + 2 más
    • Inglés
    Sustainable Agriculture and the Environment describes the relationship of agriculture, society, nature and the environment, sustainable agriculture and sustainable development goals, management of biophysical resources for sustainable food and environment, traditional knowledge and innovative options, and social and policy aspects of sustainable agriculture. The book presents both environmental and economic principles, helping readers in the development and application of robust policy and good institutional systems that execute on sustainable agriculture practices for a healthy environment and to combat climate resilience.

  • Neurología elemental

    • 3 Edición
    • Fernando Barinagarrementeria Aldatz + 3 más
    • Español
    · Auspiciada por la Academia Mexicana de Neurología, la obra va dirigida a estudiantes de pregrado; también puede ser útil para médicos residentes de la especialidad y para médicos no neurólogos que deseen repasar conceptos básicos sobre enfermedades neurológicas comunes. Asimismo, se ha renovado el panel de autores, manteniendo la pluralidad de universidades de origen. · En esta tercera edición se actualizado toda la información necesaria para que el estudiante domine la exploración, el diagnóstico y el tratamiento de las enfermedades neurológicas más habituales. Asimismo, incorpora contenido online que consiste en casos clínicos que han sido completamente renovados y presentaciones que han sido actualizadas. · Además, ofrece nuevos contenidos sobre neurología autoinmune en patologías como la demencia, la epilepsia, las infecciones de sistema nervioso central, y las enfermedades neurovasculares, neuromusculares y desmielinizantes. · En la sección de enfermedades neurológicas, incorpora algunos capítulos nuevos («Enfermedad de Parkin­son y trastornos de los movimientos comunes» y «Traumatismo craneoencefálico y raquimedular»). · Incluye un nuevo capítulo «Manifestaciones neurológicas agudas, crónicas y posvacunales en el contexto de la COVID-19», ofrece información actualizada sobre el tratamiento de patologías como las cefaleas, la epilepsia y la esclerosis múltiple, e incorpora por primera vez información sobre los estados epilépticos NORSE y FIRES y, en el capítulo sobre enfermedades desmielinizantes, acerca de la enfermedad por anticuerpos anti-MOG.

  • Pulmonary Assessment and Management of Patients with Pediatric Neuromuscular Disease

    • 1 Edición
    • Oscar Henry Mayer
    • Inglés
    Pulmonary Assessment and Management of Patients with Pediatric Neuromuscular Disease covers the broad medical problems and specific pulmonary conditions in patients with pediatric neuromuscular disease, ranging from the different types of neuromuscular disease, their pathophysiology, and assessment and management, including both novel disease modifying pharmacotherapies and state-of-the-art clinical management. This book provides evidence-based guidance for pediatric patients with neuromuscular disease, and is a valuable resource to pediatric pulmonologists, critical care physicians, and respiratory therapists who want an update and understanding on the cutting-edge therapies and standards of care for managing this population.

  • Electromagnetic Waves-Based Cancer Diagnosis and Therapy

    Principles and Applications of Nanomaterials
    • 1 Edición
    • Mona Khafaji + 1 más
    • Inglés
    Electromagnetic Waves-Based Cancer Diagnosis and Therapy: Principles and Applications of Nanomaterials is a reference solution for radiation-based methods in cancer therapy that benefit from nanosystems. The book gives foundational knowledge and the latest techniques across the electromagnetic wave spectrum. It assesses the advantages and limitations of nanosystems in therapy, providing researchers and specialists with the insight to leverage novel nanostructures for therapy and to improve the efficacy of existing methods. It presents a comprehensive reference on the use of nanosystems in radiation-based cancer therapy. What makes this book unique is its coverage of the electromagnetic wave spectrum. Six chapters cover radio-wave-involved cancer therapy and imaging; cancer therapy by microwaves hypothermia; infra-red waves in cancer theranostics; the use of visible light in diagnosis; X-ray based treatments; and gamma ray-involved therapy and imaging. This book offers researchers and specialists a comprehensive overview of radiation-based methods using nanosystems. It will be of great use to researchers and specialists in cancer diagnosis who want to take advantage of novel nanostructures and to improve the performance of conventional methods in radiation-based cancer diagnosis and therapy.

  • Berry Bioactive Compound By-Products

    • 1 Edición
    • Ibrahim Khalifa + 1 más
    • Inglés
    Berry Bioactive Compound By-Products explores the phytochemistry, functional properties, health-promoting effects, and food and non-food applications of bioactive compounds in berry processing by-products. The book covers a range of berry processing by-products, including mulberry, raspberry, blueberry, and many more. The book examines the chemical composition, bioactive compounds, green methods for extraction, metabolism and bioactivity of bioactive components, biorefinery, bioenergy, and zero waste processing, and economic values for each berry's by-products. Edited by world experts, this book is a valuable resource for food scientists, researchers, and students in the fields of functional foods and food science, technology, and bioprocess engineering.

  • Neurological Disorders in Women: From Epidemiology to Outcome, An Issue of Neurologic Clinics

    • 1 Edición
    • Volumen 41-2
    • Rima M. Dafer
    • Inglés
    In this issue of Neurologic Clinics, guest editor Dr. Rima M. Dafer brings her considerable expertise to the topic of Neurological Disorders in Women: From Epidemiology to Outcome. Top experts in the field discuss the most common neurological conditions affecting women, including stroke, migraine, multiple sclerosis, and dementia, among others, with special consideration for the management of these conditions during reproductive years of age.

  • Computational Intelligence in Cancer Diagnosis

    Progress and Challenges
    • 1 Edición
    • Janmenjoy Nayak + 5 más
    • Inglés
    Computational Intelligence in Cancer Diagnosis: Progress and Challenges provides insights into the current strength and weaknesses of different applications and research findings on computational intelligence in cancer research. The book improves the exchange of ideas and coherence among various computational intelligence methods and enhances the relevance and exploitation of application areas for both experienced and novice end-users. Topics discussed include neural networks, fuzzy logic, connectionist systems, genetic algorithms, evolutionary computation, cellular automata, self-organizing systems, soft computing, fuzzy systems, and hybrid intelligent systems. The book's chapters are written by international experts from both cancer research, oncology and computational sides to cover different aspects and make it comprehensible for readers with no background on informatics.

  • Processing of Food Products and Wastes with High Voltage Electrical Discharges

    • 1 Edición
    • Eugene Vorobiev + 2 más
    • Inglés
    Processing of Food Products and Wastes with High Voltage Electrical Discharges presents basic knowledge on HVED technology, focusing on the mechanisms, related phenomena and effects, equipment design, methods and examples of application. Divided in three parts, the book covers the advantages and restrictions of HVED technology for the treatment of numerous specific food products, by-products and wastes, such as grape, oilseed, citrus by-products and wastes, lignocellulosic and algal biomass, meat and bacterias. This book act as a comprehensive resource for researchers to be able to use the data for the dimensioning of HVED and processing equipment and finding the optimal treatment parameters.

  • Nutrition Science, Marketing Nutrition, Health Claims, and Public Policy

    • 1 Edición
    • Dilip Ghosh + 2 más
    • Inglés
    **Association of American Publishers (AAP) PROSE Award Finalist in Nursing and Allied Health Services, 2024**Nutrition Science, Marketing Nutrition, Health Claims, and Public Policy explains strategies to guide consumers toward making informed food purchases. The book begins with coverage of nutrition science before moving into nutrition marketing, social marketing and responsibility, consumer perception and insight, public health policy and regulation, case studies, and coverage on how to integrate holistic health into mainstream brand marketing. Intended for food and nutrition scientists who work in marketing, manufacturing, packaging, as well as clinical nutritionists, health care policymakers, and graduate and post graduate students in nutrition and business-related studies, this book will be a welcomed resource.

  • Control of Cell Cycle and Cell Proliferation

    • 1 Edición
    • Volumen 135
    • Rossen Donev
    • Inglés
    Control of Cell Cycle and Cell Proliferation, Volume 135 in the Advances in Protein Chemistry and Structural Biology series, presents chapters on a variety topics, including Exploiting pivotal mechanisms behind the senescence-like cell cycle arrest, Viral infection on through Cell Cycle Regulation, Analyzing drug resistant mutation in CDK4 gene and identification of potential inhibitors through structure based virtual screening approach, Controlling cell proliferation by targeting CDK6 using drug repurposing approach, The role of the nucleolus in regulating cell cycle, Chromatin regulators in DNA replication and genome stability maintenance during S-phase, Role of macrophage in cancer cell progression and targeted immunotherapies, and much more.

  • Advances in Immunology

    • 1 Edición
    • Volumen 157
    • Frederick W. Alt + 1 más
    • Inglés
    Advances in Immunology, Volume 157, the latest release in a long-established and highly respected publication, presents current developments and comprehensive reviews in immunology. Chapters in this new release include Antigen receptor structure and signaling, T cells in the brain inflammation, The molecular mechanism of RIG-I/MDA5 activation and signaling, GSDMD biology, cGAS-STING pathway, The CARD8 inflammasome in HIV infection, and much more.

  • The Cardiovascular Glycocalyx in Health and Disease

    • 1 Edición
    • Volumen 91
    • Inglés
    The Cardiovascular Glycocalyx in Health and Disease, Volume 91 gives updates on the glycocalyx function through the cardiovascular system and its integration in whole system physiology. Chapters address Endothelial surface layers in the kidney, Pharmacological targeting of the glycocalyx -- current status and prospects, The endothelial glycocalyx and the subtleties of female microcirculation, and much more targeted content.

  • Neurostimulation for Epilepsy

    Advances, Applications and Opportunities
    • 1 Edición
    • Vikram R. Rao
    • Inglés
    **Association of American Publishers (AAP) PROSE Award Finalist in Biomedicine and Neuroscience, 2024**Neurostimulati... for Epilepsy: Advances, Applications, and Opportunities comprehensively reviews the diverse array of neurostimulation technologies currently in use and in development for the treatment of epilepsy. The book covers basic mechanisms of neurostimulation, technical characteristics of approved and investigational neurostimulation devices, clinical applications and programming considerations of these devices, and progress toward next-generation device technology. Leading experts in the field provide a contemporary appraisal of neurostimulation in epilepsy, one that highlights recent advances, outlines unanswered questions, and proposes future directions.Neurostim... for Epilepsy: Advances, Applications, and Opportunities will be of high interest to clinical, basic, and translational researchers seeking to understand leading-edge applications of neurostimulation in epilepsy and to clinicians managing patients with epilepsy who are treated with implanted and external neurostimulation devices. This book will also be of interest to trainees, to physicians in other areas of neurology where neurostimulation is employed, such as Pain and Movement Disorders, and to general medical practitioners, neurobiologists, and engineers.

  • Phytoplasma Diseases of Major Crops, Trees, and Weeds

    • 1 Edición
    • A.K. Tiwari + 5 más
    • Inglés
    Phytoplasma Diseases of Major Crops, Trees, and Weeds is the second volume in a three-volume series dedicated to the analysis of plant pathogenic phytoplasmas across Asia. With a close look into the different types of plants affected by phytoplasma, the book offers management strategies to develop resistant plant strains. Phytoplasma diseases pose serious economic losses in many Asian countries, for which there is very little awareness within society. The chapters in Volume 2 comprehensively review predominant plant species and how they are impacted by phytoplasma diseases, providing information on host-pathogen interaction, characterization, and genetic diversity. The Phytoplasma Diseases in Asian Countries series will be an essential read for students, researchers and agriculturalists interested in plant pathology. Volume 2 will be of particular interest to those needing to access the latest information on plant management and successful plant breeding strategies.

  • Characterization, Epidemiology, and Management

    • 1 Edición
    • A.K. Tiwari + 5 más
    • Inglés
    Characterization, Epidemiology and Management is the third volume in the Phytoplasma Diseases in Asian Countries series dedicated to the analysis of plant pathogens across Asia. Highlighting genomic studies and molecular approaches for rapid detection of phytoplasma diseases, the book discusses effective control measures for insect vectors across Asia. The chapters in this book discuss the latest biological controls and how best to manage and even eliminate phytoplasma diseases. This is an essential read for students, researchers and agriculturalists interested in plant pathology. Phytoplasma are microorganisms that are transmitted by insect vectors, infecting various different types of annuals and perennials and causing serious damage to crops across Asia.

  • Distributed Computing to Blockchain

    Architecture, Technology, and Applications
    • 1 Edición
    • Rajiv Pandey + 2 más
    • Inglés
    Distributed Computing to Blockchain: Architecture, Technology, and Applications provides researchers, computer scientists, and data scientists with a comprehensive and applied reference covering the evolution of distributed systems computing into blockchain and associated systems. Divided into three major sections, the book explores the basic topics in the blockchain space extending from distributed systems architecture, distributed ledger, decentralized web to introductory aspects of cryptoeconomics (cryptography and economics) of decentralized applications. The book further explores advanced concepts such as smart contracts; distributed token mining, initial coin offerings; proof of work; public, private, and other blockchains; cryptography; security; and blockchains. The book goes on to review byzantine fault tolerance, distributed ledgers versus blockchains, and blockchain protocols. The final section covers multiple use cases and applications of distributed computing and the future directions for blockchains.

  • Biocompatibility Protocols for Medical Devices and Materials

    • 1 Edición
    • Prakash Srinivasan Timiri Shanmugam + 2 más
    • Inglés
    Biocompatibility Protocols for Medical Devices and Materials provides comprehensive coverage of the basic science and toxicological testing protocols necessary for the risk assessment and safety analysis of medical devices and materials which are based on the ISO guidelines for body contact and duration of contact. The book begins with device/component selection for toxicological experiments and provides an introduction to topics such as sensitization, irritation tests, material-mediated pyrogenicity, and bacterial-mediated pyrogenicity. Toxicology-related chapters explain the protocols for cytotoxicity, acute systemic toxicity, repeated-exposure systemic toxicity, genotoxicity, carcinogenicity, and reproductive toxicity testing. Biocompatibility Protocols for Medical Devices and Materials is a practical guide that provides step-by-step toxicological protocols ranging from materials selection to data interpretation for toxicologists, biomedical researchers, healthcare professionals, product developers, and others working in risk assessment and safety analysis of medical devices.

  • Game-Based Learning in Education and Health - Part A

    • 1 Edición
    • Volumen 276
    • Inglés
    Game-Based Learning in Education and Health, Volume 276 in the Progress in Brain Research series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Math computerized games in the classroom: a Number Line Training in Primary School Children, Digital games for learning basic arithmetic at home, Game-Based Assessment of Cognitive Function among Children and Adolescents: A Systematic Review and Meta-Analysis, Different aspects of fraction understanding are associated selectively with performance on a fraction learning game, and more.

  • All About Bioinformatics

    From Beginner to Expert
    • 1 Edición
    • Yasha Hasija
    • Inglés
    All About Bioinformatics: From Beginner to Expert provides readers with an overview of the fundamentals and advances in the _x001F_field of bioinformatics, as well as some future directions. Each chapter is didactically organized and includes introduction, applications, tools, and future directions to cover the topics thoroughly. The book covers both traditional topics such as biological databases, algorithms, genetic variations, static methods, and structural bioinformatics, as well as contemporary advanced topics such as high-throughput technologies, drug informatics, system and network biology, and machine learning. It is a valuable resource for researchers and graduate students who are interested to learn more about bioinformatics to apply in their research work.

  • Translational Interventional Radiology

    • 1 Edición
    • Adam E.M. Eltorai + 3 más
    • Inglés
    Translational Interventional Radiology, a volume in the Handbook for Designing and Conducting Clinical and Translational Research series, covers the principles of evidence-based medicine and applies these principles to the design of translational investigations in Interventional Radiology. The reader will come to fully understand important concepts including case-control study, prospective cohort study, randomized trial, and reliability study. Medical researchers will benefit from greater confidence in their ability to initiate and execute their own investigations, avoid common pitfalls in Interventional Radiology, and know what is needed for successful collaboration. Further, this reference is an indispensable tool in grant writing and funding efforts. The practical, straightforward approach helps aspiring investigators navigate challenging considerations in study design and implementation. This book provides valuable discussions of the critical appraisal of published studies in Interventional Radiology, elucidating the evaluation of the quality with respect to measuring outcomes and making effective use of all types of evidence in patient care. In short, this practical guide will be of interest to every medical researcher and interventional radiologist who has ever had a good clinical idea but not the knowledge of how to test it.

  • Atlas of Hybrid Imaging Sectional Anatomy for PET/CT, PET/MRI and SPECT/CT Vol. 3: Heart, Lymph Node and Musculoskeletal System

    Sectional Anatomy for PET/CT, PET/MRI and SPECT/CT
    • 1 Edición
    • Mario Leporace + 5 más
    • Inglés
    Atlas of Hybrid Imaging of the Heart, Lymph Nodes and Musculoskeletal System, Volume Three: Sectional Anatomy for PET/CT, PET/MRI and SPECT/CT provides a guide for interpreting PET and SPECT in relation to co-registered CT and/or MRI. In this atlas, exclusively dedicated to heart, lymph nodes and musculoskeletal system, nuclear physicians and radiologists cover hybrid nuclear medicine based on their own case studies. The practical structure in two-page unit offers readers a navigational tool based on anatomical districts, with labeled and explained low-dose multiplanar CT or MRI views merged with PET fusion imaging on one side and enhanced CT or MRI on the other. This new format enables the rapid identification of hybrid nuclear medicine findings which are now routine at leading medical centers. Each chapter begins with three-dimensional CT and/or MRI views of the evaluated anatomical region, bringing forward sectional tables. Clinical cases, tricks and pitfalls linked to several PET or SPECT radiopharmaceuticals help introduce the reader to peculiar molecular pathways and improve confidence in cross-sectional imaging that is vital for accurate diagnosis and treatments.

  • Atlas of Hybrid Imaging Sectional Anatomy for PET/CT, PET/MRI and SPECT/CT Vol. 2: Thorax Abdomen and Pelvis

    Sectional Anatomy for PET/CT, PET/MRI and SPECT/CT
    • 1 Edición
    • Mario Leporace + 5 más
    • Inglés
    Atlas of Hybrid Imaging of the Thorax, Abdomen and Pelvis, Volume Two: Sectional Anatomy for PET/CT, PET/MRI and SPECT/CT provides a guide for interpreting PET and SPECT in relation to co-registered CT and/or MRI. In this atlas, exclusively dedicated to thorax, abdomen and pelvis, nuclear physicians and radiologists cover hybrid nuclear medicine based on their own case studies. The practical structure in two-page unit offers readers a navigational tool based on anatomical districts, with labeled and explained low-dose multiplanar CT or MRI views merged with PET fusion imaging on one side and enhanced CT or MRI on the other. This new format enables the rapid identification of hybrid nuclear medicine findings which are now routine at leading medical centers. Each chapter begins with three-dimensional CT and/or MRI views of the evaluated anatomical region, bringing forward sectional tables. Clinical cases, tricks and pitfalls linked to several PET or SPECT radiopharmaceuticals help introduce the reader to peculiar molecular pathways and improve confidence in cross-sectional imaging that is vital for accurate diagnosis and treatments.

  • Atlas of Hybrid Imaging Sectional Anatomy for PET/CT, PET/MRI and SPECT/CT Vol. 1: Brain and Neck

    Sectional Anatomy for PET/CT, PET/MRI and SPECT/CT
    • 1 Edición
    • Mario Leporace + 5 más
    • Inglés
    For the first time, in this atlas nuclear physicians and radiologists cover the entire hybrid nuclear medicine (PET/CT, SPECT/CT and PET/MRI), based on their own case studies. The structure in three volumes represents an user friendly guide for interpreting PET and SPECT in relation to co-registered CT and/or MRI. Three companion volumes with a practical structure in two-page unit offer to the reader a navigational tool, based on anatomical districts, with labeled and explained low-dose multiplanar CT or MRI views merged with PET fusion imaging on the right hand and contrast enhanced CT or MRI on the other side. This new format enables rapid identification of hybrid nuclear medicine findings which are now routine at leading medical centers. Volume 1 is focused on brain and neck PET imaging, with emphasis on PET/MRI; Volume 2 concerns thorax, abdomen and pelvis, with particular attention on lung and liver segmental anatomy and evaluation of peritoneum. Special chapters on heart, lymph nodes and musculoskeletal system, are collected in the Volume 3. Each chapter begins with three-dimensional CT and/or MRI views of the evaluated anatomical region, bringing forward sectional tables. Clinical cases, tricks and pitfalls linked to several PET or SPECT radiopharmaceuticals help to introduce the reader to peculiar molecular pathways and to improve confidence in cross-sectional imaging, that is vital for the accurate diagnosis and treatment of diseases.

  • Profiles of Drug Substances, Excipients, and Related Methodology

    • 1 Edición
    • Volumen 48
    • Abdulrahman Al-Majed
    • Inglés
    Profiles of Drug Substances, Excipients, and Related Methodology, Volume 48 encompasses review articles and database compilations that fall within one or more of the following five broad categories: Physical Profiles of Drug Substances and Excipients; Analytical Profiles of Drug Substances and Excipients; ADME Profiles of Drug Substances and Excipients; Methodology Related to the Characterization of Drug Substances and Excipients; Methods of Chemical Synthesis. There is no comparable book series that gives this crucial information in such a timely and relevant manner. The volume offers in-depth profiles of Brimonidine, Cristine, Remdesivir, Vandetanib, and Lapatinib. It also includes an additional chapter on Pharmaceutical-Based Cosmetic Serums.

  • Principles of Gender-Specific Medicine

    Sex and Gender-Specific Biology in the Postgenomic Era
    • 4 Edición
    • Marianne Legato J
    • Inglés
    Awarded with the 2018 Prose Award in Clinical Medicine, the third edition of Principles of Gender-Specific Medicine explored and described exciting new areas in biomedicine that integrated technology into the treatment of disease and the augmentation of human function. Novel topics such as the sex-specific aspects of space medicine, the development and the use of genderized robots and a discussion of cyborgs were included in the third edition, providing a preview of the expanding world of sex-specific physiology and therapeutics. This Fourth Edition is a continuation of the mission to trace the relevance of biological sex to normal function and to the experience of disease in humans.We are now twenty years into the postgenomic era. The investigation of how the genome produces the phenome has led to fascinating insights as well as yet unanswered questions. Principles of Gender-Specific Medicine, Fourth Edition, has a central theme: discuss advances in understanding the role of epigenetics in regulating gene expression in a dynamic, sex-specific way during human life. It explores the protean role of epigenetics in human physiology, the relevance of environmental experience to human function, the therapeutic promise of cutting-edge methodologies like gene manipulation, the preparation of humans for space travel, the use of artificial intelligence in detection and therapeutic decisions concerning disease states, the possibilities for technological support of not only compromised individuals but of the augmentation of human function, and an analysis of the benefits, limitations and issues that surround our current expectations of personalized medicine.

  • Nanoparticles and Plant-Microbe Interactions

    An Environmental Perspective
    • 1 Edición
    • Sahadevan Seena + 2 más
    • Inglés
    Nanoparticles and Plant-Microbe Interactions: An Environmental Perspective, Volume Seven in the Nanomaterial-Plant Interactions series, provides comprehensive coverage on how nanoparticles can impact plant-microbe interactions. Key themes include nanoparticle synthesis, nano-phytoremediatio... nano-farming, the negative impacts of nanoparticles, and nanomaterials in mitigating stress. This will be an essential read for any scientist or researcher looking to assess and understand the potential toxicological risks associated with plant nanotechnology, with particular focus on plant-microbe interactions. Nanotechnology is an emerging field with a vast range of nano-based products for commercial exploitation. The interactions of nanoparticles, plants and microbes can be harnessed in several applications, including alleviating environmental pollution. In addition to the aforementioned content, the book also explores concerns surrounding the toxicity of nanoparticles themselves, an important aspect to be aware, along with potential negative effects.

  • Epigenetics in Health and Disease

    • 1 Edición
    • Volumen 197
    • Inglés
    Epigenetics in Health and Disease, Volume 197 in the Progress in Molecular Biology and Translational Science series, highlights new advances in the field, with this new volume presenting interesting chapters on An Introduction to epigenetics in health and disease, State-of-the-art techniques for epigenetics study, Computational biology in epigenetics, Artificial intelligence and machine learning in epigenetics, CRISPR-Cas systems in epigenetics modification for health, Mechanisms of DNA methylation and histone modifications, Non-coding RNA in epigenetics, Role of DNA Methylation in cardiovascular diseases, Role of epigenetics in renal diseases, and much more. Additional chapters update on Histone modifications in fat metabolism and obesity, Role of DNA methylation in diabetes and obesity, Epigenetic regulons in Alzheimer’s disease, Epigenetics in heredity disease, Epigenetics of aging, Epigenetics in cancer development, diagnosis and therapy, Microbiota and epigenetics: health impact, Epigenetics in Fetal Alcohol Spectrum disorder, and much more.

  • Innovation of Food Products in Halal Supply Chain Worldwide

    • 1 Edición
    • Aishah Bujang + 2 más
    • Inglés
    Innovation of Food Products in the Halal Supply Chain Worldwide covers the fundamentals and food guidelines of halal food production. Unlike other texts on the halal food market and halal certification, this book promotes halal product innovation by presenting exciting newly developed ingredients that are substitutions of non-halal ingredients with halal alternatives, such as lard substituted with modified vegetable fats, pig with halal goat/beef/camel/fish gelatin/collagen, alternative meat substitute or even additives. Innovations in halal processing technologies cover the latest techniques in halal production and authentication, halal tracking/traceabilit... in halal transport and logistics, a vast area at the end of a supply chain. All chapters are written by acknowledged experts in their field, thus the book brings together the top researchers in this essential topic of importance to a huge percentage of the world’s population.

  • Diversity, Distribution, and Current Status

    • 1 Edición
    • A.K. Tiwari + 4 más
    • Inglés
    Diversity, Distribution, and Current Status is the first volume in a three-volume series dedicated to the analysis of this important group of plant pathogens across Asia with a particular focus on geographic distribution. This book offers updated data on the most prevalent phytoplasma diseases specific to each region. Phytoplasmas are emerging plant pathogens all around the world, causing significant economic losses to crops, as well as affecting international trade. The chapters in Volume 1 look closely at different countries and regions across Asia, providing data on country-wide distribution, phytoplasma groups, insect vectors and transmission. The Phytoplama Diseases in Asian Countries series will be an essential read for university students, researchers and agriculturalists interested in Plant Pathology. Volume 1 will be of particular interest to those needing the latest data on the distribution and transmission rates specific to the various regions of Asia.

  • Pulping and Papermaking of Nonwood Plant Fibers

    • 1 Edición
    • Z.M.A. Ainun + 2 más
    • Inglés
    Pulping and Papermaking of Non-wood Plant Fibres presents the latest technologies associated with the papermaking process. With chapters specific to each non-wood species, the book provides step-by-step guidance on processes such as pulping, bleaching, blending and beating. Non-wood fibers are practical for pulp and paper production due to their chemical content of cellulose, hemicellulose and lignin percentages. Beginning with a general overview of non-wood fibers in the papermaking process, chapters then take a deep dive into different raw materials and their processes, including bamboo, corn stalk, pineapple leaves and sugarcane. This book is an essential resource for researchers, scientists and industry specialists.

  • The Eye

    • 1 Edición
    • Volumen 4
    • Eman E. Taher + 1 más
    • Inglés
    The Eye, Volume Four, the latest release in the Stem Cell Innovation in Health and Disease series, addresses the recent data accumulated on the potential applications of stem cells to treat eye diseases. This volume highlights the recent development of cutting-edge in vitro and in vivo research tools and approaches, including human and murine organoid cultures, genetic editing in vitro and in vivo, human iPSC models of disease, haploid cells for genetic as well as compound screening paradigms, genetically engineered mice, and stem cell transplantation to cure eye diseases. The volume is written for researchers and scientists in stem cell therapy, cell biology, regenerative medicine and organ transplantation, and is contributed by world-renowned authors in the field. This is a timely and fascinating collection of information and new discoveries that provides a contemporary snapshot album on the fast-moving field of regenerative medicine and stem cell therapeutics.

  • Nutraceuticals

    Sources, Processing Methods, Properties, and Applications
    • 1 Edición
    • Tariq Altalhi + 2 más
    • Inglés
    Nutraceuticals: Sources, Processing Methods, Properties, and Applications explores the impact of nutraceutical compounds on human health and their main pharmacological contributions. Organized into three parts, this book addresses nutraceutical production, applications for disease prevention and treatment, and current trends, especially the role of nutraceuticals in cosmeceutical. Nutraceuticals are a class of products that can help people improve their health, reduce the risk of disease, extend their lives, and control the structure and functioning of their bodies. However, due to multiple hurdles that prevent nutraceuticals from circulating in an active form in the body, their use is associated with diminished therapeutic efficacy. Recognizing this problem, the book explores the root of the nutraceutical delivery system and its codelivery methods with a focus on medicines. With contributions from experienced nutraceutical experts, this book serves as a valuable reference for nutrition researchers, food scientists, pharmacologists, and those who are researching and studying in related areas.

  • PACE Yourself

    Alcohol, Addiction and Exercise
    • 1 Edición
    • Megan Johnson Mccullough
    • Inglés
    PACE Yourself: Alcohol, Addiction and Exercise provides qualitative research about the influence of exercise on alcohol use disorder (AUD) recovery. In addition, the author explains how someone can benefit from exercise and explores how the PACE method could help keep new addictions at bay. PACE is an acronym for Proactive Awareness Controlling Excess. The author has developed an app of the same name which is available in the Apple store. Exercise is medicine when it comes to the recovering body and mind of an alcoholic. Physiological and psychological changes as a result of moving the body contribute to prolonged sobriety and deter the cyclical threat the nature of alcohol abuse can pose upon person in recovery. The struggle to never become powerless to alcohol again can be kept at bay when the benefits of exercise over power the benefits alcohol used to have. However, the addictive mind can find a new habit to replace the old one. The PACE method proposes steps to become aware of replacement type behaviors with the understanding that anyone can become addicted to anything.

  • MRI and Traumatic Brain Injury, An Issue of Neuroimaging Clinics of North America

    • 1 Edición
    • Volumen 33-2
    • Pejman Jabehdar Maralani + 1 más
    • Inglés
    In this issue of Neuroimaging Clinics, guest editors Drs. Pejman Jabehdar Maralani and Sean Symons bring their considerable expertise to the topic of Neurotrauma. Top experts in the field cover key topics such as conventional MRI in trauma management in adults and children; imaging approach to concussion; clinical updates on concussion; the current state of DWI/DTI for trauma prognostication; the current state of fMRI/rs-fMRI for trauma prognostication; and more.

  • Ionizing Radiation and the Immune Response - Part A

    • 1 Edición
    • Volumen 376
    • Inglés
    Ionizing Radiation and the Immune Response, Volume 376, Part A reviews the latest updates on the immune response induced by ionizing radiations. Sections discuss NK functions in radio-induced immune response, TRT and immune response, Radio-induced immune response and lipid metabolism, Effect of protons and heavy ions on immune response, Effect of flashtherapy and mini beam on immune response, Radio-induced lymphopenia, CT to potentiate radio-induced immune response, Impact of RT on healthy tissues (inflammation), Radio-induced macrophagic response, To use nanoparticles and ionizing radiations to modulate immune response: opinion of the chemist, biologist and clinician, and more. Additional sections touch on the Effect of low dose radiation on radio-induced immune response, Role of Dendritic cells in radiation-induced immune response, Relationship between the tumor microenvironment and the efficacy of the radiotherapy/immunot... combination+A23, and Biomarkers of radiation induced response to optimize radio-immunotherapy combination.

  • Food Safety Management

    A Practical Guide for the Food Industry
    • 2 Edición
    • Veslemøy Andersen + 2 más
    • Inglés
    Food Safety Management: A Practical Guide for the Food Industry, Second Edition continues to present a comprehensive, integrated and practical approach to the management of food safety throughout the production chain. While many books address specific aspects of food safety, no other book guides you through the various risks associated with each sector of the production process or alerts you to the measures needed to mitigate those risks. This new edition provides practical examples of incidents and their root causes, highlighting pitfalls in food safety management and providing key insights into different means for avoiding them. Each section addresses its subject in terms of relevance and application to food safety and, where applicable, spoilage. The book covers all types of risks (e.g., microbial, chemical, physical) associated with each step of the food chain, making it an ideal resource.

  • Ophthalmic Pathology

    The Evolution of Modern Concepts
    • 1 Edición
    • Curtis E. Margo
    • Inglés
    Ophthalmic Pathology: The Evolution of Current Concepts examines how our current understanding of morphologic disease, nomenclature and classification over the last century came about. The book explores the historical context and the modern trends of ocular nosology, emphasizing the science of disease classification. Chapters highlight major studies and developments surrounding approximately 50 disorders whose diagnoses are established by pathology, corresponding to a historical road map of current nomenclature, methods of disease classification, and the role of diagnostic morphology. Using a streamlined, highly illustrated format, this book provides a unique historic and evolutionary perspective into current views on the morphology of eye disease.

  • Organ-Specific Parasitic Diseases of Dogs and Cats

    • 1 Edición
    • Tanmoy Rana
    • Inglés
    Organ-Specific Parasitic Diseases of Dogs and Cats takes an organ-specific approach to the impact of parasitic diseases in dogs and cats. This book provides a detailed description of the key role that parasites play in the pathogenesis of diseases, explores the manifestation of symptoms and diagnosis, and offers prevention and treatment strategies to counteract parasitic infections. An introduction by the editor is followed by chapters from various authors covering parasitic diseases in specific organs and organ systems. The book also provides an overview on the diagnostic evaluation of parasitic diseases. Parasite control, travel management, therapeutic measures, and disease control strategies round out the discussion. With contributions from experts in the field, this book serves as a useful resource to researchers, academics, and postgraduates who wish to expand their knowledge on parasitic diseases, diagnosis, and treatment, and as a reference for scientists looking to develop new antiparasitic drugs.

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