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Elsevier

Libros en Ciencias de la Vida

  • Protein Design and Structure

    • 1 Edición
    • Volumen 130
    • Rossen Donev
    • Inglés
    Protein Design and Structure, Volume 130 in the Advances in Protein Chemistry and Structural Biology series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Neurosurgery for Neurologists, An Issue of Neurologic Clinics

    • 1 Edición
    • Volumen 40-2
    • Russell R. Lonser + 1 más
    • Inglés
    In this issue of Neurologic Clinics, guest editors Drs. Russell R. Lonser and Daniel K. Resnick bring their considerable expertise to the topic of Neurosurgery for Neurologists. Top experts in the field cover key topics such as indications and advances in surgical epilepsy, critical care management of traumatic brain injury, neurosurgical mimics, surgical neuro-oncology, and more.

  • Bioinformatics in Agriculture

    Next Generation Sequencing Era
    • 1 Edición
    • Pradeep Sharma + 2 más
    • Inglés
    Bioinformatics in Agriculture: Next Generation Sequencing Era is a comprehensive volume presenting an integrated research and development approach to the practical application of genomics to improve agricultural crops. Exploring both the theoretical and applied aspects of computational biology, and focusing on the innovation processes, the book highlights the increased productivity of a translational approach. Presented in four sections and including insights from experts from around the world, the book includes: Section I: Bioinformatics and Next Generation Sequencing Technologies; Section II: Omics Application; Section III: Data mining and Markers Discovery; Section IV: Artificial Intelligence and Agribots. Bioinformatics in Agriculture: Next Generation Sequencing Era explores deep sequencing, NGS, genomic, transcriptome analysis and multiplexing, highlighting practices forreducing time, cost, and effort for the analysis of gene as they are pooled, and sequenced. Readers will gain real-world information on computational biology, genomics, applied data mining, machine learning, and artificial intelligence. This book serves as a complete package for advanced undergraduate students, researchers, and scientists with an interest in bioinformatics.

  • Artificial Intelligence and Machine Learning for EDGE Computing

    • 1 Edición
    • Rajiv Pandey + 3 más
    • Inglés
    Artificial Intelligence and Machine Learning for Predictive and Analytical Rendering in Edge Computing focuses on the role of AI and machine learning as it impacts and works alongside Edge Computing. Sections cover the growing number of devices and applications in diversified domains of industry, including gaming, speech recognition, medical diagnostics, robotics and computer vision and how they are being driven by Big Data, Artificial Intelligence, Machine Learning and distributed computing, may it be Cloud Computing or the evolving Fog and Edge Computing paradigms. Challenges covered include remote storage and computing, bandwidth overload due to transportation of data from End nodes to Cloud leading in latency issues, security issues in transporting sensitive medical and financial information across larger gaps in points of data generation and computing, as well as design features of Edge nodes to store and run AI/ML algorithms for effective rendering.

  • Cholesterol

    From Chemistry and Biophysics to the Clinic
    • 1 Edición
    • Anna N. Bukiya + 1 más
    • Inglés
    With Cholesterol, Drs. Anna Bukiya and Alex Dopico have compiled a comprehensive resource on biological and clinical aspects of cholesterol, spanning biophysics and biochemistry, as well as the latest pharmacological discoveries employed to tackle disorders associated with abnormal cholesterol levels. Early chapters on basic biology offer guidance in cholesterol lab chemistry, cholesterol metabolism and synthesis, molecular evolution of cholesterol and sterols, cholesterol peptides, and cholesterol modulation. Chapters on cellular and organismal development discuss cholesterol transport in blood, lipoproteins, and cholesterol metabolism; cholesterol detection in the blood; cellular cholesterol levels; hypercholesterolemia... and the role of cholesterol in early human development. Pathophysical specialists consider familial hypobetalipoproteine... critical illness and cholesterol levels, coronary artery disease, CESD, cholesterol and viral pathology, cholesterol and neurodegenerative disorders, and cholesterol and substance use disorders. A final section examines pharmacology of drug delivery systems targeting cholesterol related disorders, cholesterol receptors, cholesterol reduction, statins, citrate lyase, cyclodextrins, and clinical management. Cholesterol: From Biophysics and Biochemistry to Pathology and Pharmacology empowers researchers, students, and clinicians across various disciplines to advance new cholesterol-based studies, improve clinical management, and drive drug discovery.

  • Lactic Acid Bacteria in Food Biotechnology

    Innovations and Functional Aspects
    • 1 Edición
    • Spiros Paramithiotis + 2 más
    • Inglés
    Lactic Acid Bacteria in Food Biotechnology: Innovations and Functional Aspects describes the latest advancements in LAB applications in the development of functional foods and fermented foods, biotechnological products using LAB, i.e., bio chemicals (organic acids, bacteriocins, etc.), bioactive and functional biomolecules, comparative genomics of probiotic LAB, and genetically modified LAB in food industry. Bridging the gap between LAB-mediated fermented foods and bioactive compounds, vis-a-vis molecular aspects, this book enables the transition from research to application. The book details applications of LAB in fermented/functional foods including cereals, vegetables, fish, meat cheese, other dairy products, and much more. Other sections cover their biochemistry and biotechnology aspects, bio preservation by bio molecules produced by LAB, bioactive metabolites and biosurfactants, including their value in health and wellness and exploring the genomics of LAB from food to health. Finally, the book addresses genetically modified lactic acid bacteria in food and beverages.

  • Hepatic Fibrosis

    Mechanisms and Targets
    • 1 Edición
    • Pablo Muriel
    • Inglés
    Hepatic Fibrosis: Mechanisms and Targets is a complete volume of liver extracellular matrix biology, including molecular signaling pathways, cells and factors that modulate fibrogenesis and fibrosis. The book uses an integrated approach toward the molecular and cellular mechanisms involved in the synthesis and degradation of hepatic fibrotic tissue, emphasizing the possible molecular targets to fight fibrosis. This important reference describes, in detail and didactically, the cellular and molecular events that are conducive to fibrosis that leads to cirrhosis, hepatocellular carcinoma and death. The provided information allows readers to understand the molecular mechanisms of hepatic fibrogenesis to accelerate the development of new therapies.

  • Advances in Immunology

    • 1 Edición
    • Volumen 153
    • Frederick W. Alt + 1 más
    • Inglés
    Advances in Immunology, Volume 153, the latest release in a long-established and highly respected publication, presents current developments and comprehensive reviews in immunology, with this volume covering Regulatory T Cells in Infection and Factor H and Properdin and their regulation.

  • Advances in Biomolecular EPR

    • 1 Edición
    • Volumen 666
    • Inglés
    Advances in Biomolecular EPR, Volume 666 in the Methods of Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters on topics including Magnetic Resonance Characterization of Physiologically Important Metal Ion Binding Sites in the Prion and Related Proteins, The catalytic role of metal-radical/protei... radicals in heme enzymes, Rigid Cu2+-based spin labels for the study of higher-order DNA G-quadruplex structures, Orthogonal spin labeling and membrane proteins: increasing the information content and going towards in cell applications, Spectroscopic investigation of mono- and di-Mn-containing centers in biochemistry with an emphasis on application of paramagnetic resonance techniques, and more. Additional chapters cover In Vivo pO2 Imaging of Tumors: Oxymetry with Very Low-Frequency Electron Paramagnetic Resonance, an Update, EPR contributions to understanding molybdenum-containin... enzymes, EPR spectroscopy of Type I reaction centers, Characterization of a substrate-derived radical in the NosN reaction during the biosynthesis of nosiheptide, and much more.

  • Toxicity of Nanoparticles in Plants

    An Evaluation of Cyto/Morpho-physiological, Biochemical and Molecular Responses
    • 1 Edición
    • Vishnu D. Rajput + 4 más
    • Inglés
    Toxicity of Nanoparticles in Plants: An Evaluation of Cyto/Morpho-physiolo... Biochemical and Molecular Responses, Volume Five in the Nanomaterial-Plant Interactions series, reviews the latest research on toxicological effects of using nanotechnology in plants. Key themes include analyzing plant exposure to nanomaterials, mechanisms of toxicity of nanoparticles to plants, and effects, uptake and translocation of various different nanoparticles. This will be an essential read for any scientist or researcher looking to assess and understand the potential toxicological risks associated with plant nanotechnology. To date, nanotechnology is considered one of the most promising areas of research due to the widespread applications of nanomaterials in plant science and agriculture. However, extensive use of nano-based products raises concerns regarding their toxicity in crop plants, their environmental impact and potential consequences to humans via the food chain.

  • Transcultural Artificial Intelligence and Robotics in Health and Social Care

    • 1 Edición
    • Irena Papadopoulos + 3 más
    • Inglés
    Transcultural Artificial Intelligence and Robotics in Health and Social Care provides healthcare professionals with a deeper understanding of the incredible opportunities brought by the emerging field of AI robotics. In addition, it provides robotic researchers with the point-of-view of healthcare professionals to understand what the healthcare sector – as well as the market – really needs from robotics technology. By doing so, the book fills an important gap between both fields in order to leverage new developments and collaborative work in favor of global patients. The book is aimed at the non-technical reader, especially health and social care professionals, and explains in a simple way the technological principles applied in the development of socially assistive humanoid AI robots (SAHR), the values which guide such developments, the ethics related to them, and research approaches in the field, with a focus on achieving a culturally competent SAHR.

  • Advances in Applied Microbiology

    • 1 Edición
    • Volumen 118
    • Geoffrey M. Gadd + 1 más
    • Inglés
    Advances in Applied Microbiology, Volume 118 continues the comprehensive reach of this widely read and authoritative review source in microbiology. Users will find invaluable references and information on a variety of areas relating to the topics of microbiology.

  • Advances in Microbial Physiology

    • 1 Edición
    • Volumen 80
    • Inglés
    Advances in Microbial Physiology, Volume 150 in this important serial, highlights new advances in the field with this new volume including content by an international board of authors. Chapters in this new release include Organization of respiratory chains in the bacterial cell, Anaerobic methane oxidizing archaea, Dawn of the DedA: the structure and function of the DedA family of integral membrane proteins associated with bacterial viability and antimicrobial resistance, Nickel, an essential virulence determinant of Helicobacter pylori: trafficking pathways and their targeting by bismuth, Dissimilatory sulfur compounds oxidation in thermophilic and chemolithoautotrophi... bacteria belonging to the Aquificales order, and much more.

  • Sustainable Horticulture

    Microbial Inoculants and Stress Interaction
    • 1 Edición
    • Musa Seymen + 3 más
    • Inglés
    Sustainable Horticulture: Microbial Inoculants and Stress Interaction gives insights into the applications and formulations of microbial inoculants. In recent years, the optimum yields of horticultural plants largely influenced by rising global temperature, biotic stress (attack of pathogens) and abiotic stresses has created extra pressure for the horticulturalist to meet the need of optimum yield production for the burgeoning global population. However, the challenges of biotic and abiotic stress factors mitigated by traditional physical or chemicals methods include high application cost and adverse impact on quality limit the frequent use, hence the solutions in this book create new avenues for progress. This book covers those challenges and how microbial based bio inoculants are broadly used in horticulture to mitigate the challenges of biotic and abiotic stresses. It provides an important contribution on how to apply efficient beneficial microbes (microbial inoculants) for a sustainable society.

  • Pancreas and Beta Cell Replacement

    • 1 Edición
    • Volumen 1
    • Wayne Hawthorne
    • Inglés
    Pancreas and Beta Cell Replacement is the inaugural volume of the Regenerative and Transplant Medicine series. The idea for this new book series spawned from the observation that the regenerative medicine field is progressing at such a fast pace that the way we currently think and practice transplant medicine is rapidly changing, faster than we could ever imagine.　 This series was therefore conceived to bring together experts from both the transplant and regenerative medicine fields, to share knowledge first, but also to introduce the transplant audience to the remarkable progress that has occurred in regenerative medicine over the past few decades. At the same time, we intend to illustrate to researchers and operators in the regenerative medicine field the numerous platforms that transplant medicine offers for the application of their technologies. To the publisher and the editors of this series and volumes there is no doubt that regenerative medicine will shape and define the future of transplant medicine.　 This volume focuses on pancreas and beta cell replacement and illustrates how progress in biomaterial sciences, stem cell biology, gene editing, cell, tissue and organ bioengineering and regeneration, along with advances in xenotransplantation are revolutionizing the field. Written by the world’s experts in the fields of pancreas, islet and xenotransplantation, as well as regenerative medicine, it represents a valuable educational tool for those in the fields of clinical transplantation, researchers in the field of regenerative medicine, transplant medicine, diabetes and immunology, as well as for medical and health science students, those in academia, the biotech industry and regulatory agencies working to advance the field. At the end of the book, it will become clear to the reader that beta cell replacement offers a vast array of platforms for the application of regenerative medicine technologies to transplant medicine. 　

  • Feedback Control for Personalized Medicine

    • 1 Edición
    • Esteban A. Hernandez-Vargas
    • Inglés
    Feedback Control for Personalized Medicine provides ideas on ongoing efforts and obstacles by members of the control engineering community in different biological and medical applications. In addition, the book presents key challenges, insights, tools and theoretical developments that arise from personalized medicine, along with medical concepts that are explained by engineers to help non-experts follow research topics. Several clinical trials have tried to find therapeutic approaches to achieve eradication or at least lifelong, therapy-free, host control of the infection. This has been performed integrating clinical observations, empirical knowledge and information from medical tests to treat patients. As this “trial and error” approach is becoming more challenging and unfeasible by the steep increase in the number of different pieces of information and the complexity of large datasets, a systematic and tractable approach that integrates a variety of biological and medical research data into mathematical models and computational algorithms is crucial to harness knowledge and to develop new therapies towards personalized medicine.

  • Stem Cells and COVID-19

    • 1 Edición
    • Chandra P. Sharma + 2 más
    • Inglés
    Stem Cells and COVID-19 presents up-to-date knowledge on the effect of hematopoietic and mesenchymal stem cells to combat SARS-CoV-2 infection in its diagnosis, treatment and prevention. In addition, the book critically discusses challenges, highlighting outstanding questions and future perspectives. Written by global experts in the field for both pre-clinical and clinical practitioners, this comprehensive book delves into how stem cells have a strong potential in developing better diagnostic, treatment and preventive strategies in SARS-CoV-2 infection. Both hematopoietic and mesenchymal stem cells are critical to better understand the response of immune system to coronavirus infection in both healthy and co-morbid conditions in the development of effective vaccines and immunotherapies.

  • Stromal Signaling in Cancer

    • 1 Edición
    • Volumen 154
    • Inglés
    Stromal Signaling in Cancer, Volume 154 in the Advances in Cancer Research series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics surrounding cancer research. Each chapter is written by an international board of authors.

  • Soybean Physiology and Genetics

    • 1 Edición
    • Volumen 102
    • Inglés
    Soybean Physiology and Genetics, Volume 102 presents comprehensive reviews on the latest development in soybean research, covering soybean genomics, physiology and genetics under biotic and abiotic stress, growth and development, nitrogen fixation and nutritional values, etc. Chapters in this new release cover Root Physiology and Morphology in Relationship to Stress Tolerance, Soybean Insects, Application of Genomic Studies in Soybean Breeding, Secondary metabolism in soybean, The roles of CLE peptides in nitrogen fixation in soybean, Seed morphology in soybean, Physiology and genetic regulations of oil and protein contents in soybean, Regulation of flowering and maturation in soybean, and much more. As soybeans are a key component in climate-smart agriculture because of their high nutritional value, large cultivation area, and nitrogen-fixing ability, this book fills a gap in information on this growing commodity.

  • One, No one, One Hundred Thousand - The Multifaceted Role of Macrophages in Health and Disease - Part A

    • 1 Edición
    • Volumen 367
    • Inglés
    One, No one, One Hundred Thousand - The Multifaceted Role of Macrophages in Health and Disease - Part A, provides in-depth reviews on the last progresses on the role of macrophages in health and diseases with a special focus on the role of macrophages in SARS-COV2, breast cancer, liver and salivary glands.

  • Immunoinformatics of Cancers

    Practical Machine Learning Approaches Using R
    • 1 Edición
    • Nima Rezaei + 1 más
    • Inglés
    Immunoinformatics of Cancers: Practical Machine Learning Approaches Using R takes a bioinformatics approach to understanding and researching the immunological aspects of malignancies. It details biological and computational principles and the current applications of bioinformatic approaches in the study of human malignancies. Three sections cover the role of immunology in cancers and bioinformatics, including databases and tools, R programming and useful packages, and present the foundations of machine learning. The book then gives practical examples to illuminate the application of immunoinformatics to cancer, along with practical details on how computational and biological approaches can best be integrated.This book provides readers with practical computational knowledge and techniques, including programming, and machine learning, enabling them to understand and pursue the immunological aspects of malignancies.

  • Mouse Models of Development and Disease

    • 1 Edición
    • Volumen 148
    • Inglés
    Mouse Models of Development and Disease, Volume 148 in the Current Topics in Developmental Biology series, highlights new advances in the field, with this volume presenting chapters describing Mouse models of Charcot-Marie-Tooth disease, Mouse models in palate and craniofacial development, Uterine morphogenesis, Improving the translatability of mouse models of Alzheimer's disease, Mouse models for the study of clustered protocadherins, Mechanisms of organ regeneration in the spiny mouse, Comparative studies of organ vascularization, Modeling human urinary tract development and hereditary malformations, Innervation in organogenesis, Between embryo and adult: somatic growth of the kidney, and Mouse models in the study of Notch signaling.

  • Importance of Microbiology Teaching and Microbial Resource Management for Sustainable Futures

    • 1 Edición
    • Ipek Kurtboke
    • Inglés
    Importance of Microbiology Teaching and Microbial Resource Management for Sustainable Futures brings experts together to highlight the importance of microbiology-discipl... teaching with its unique skills-based approaches. The book discusses how microscope microbiology has received significant attention since microorganisms played a significant role in the advancement, as well as destruction of, mankind during incidences such as the black death. With the discovery of penicillin from a fungal culture, the beneficial role of microorganisms has been a major catalyst in the progress of biological sciences.Interesting... there are fundamental aspects of microbiology that did not change since revelations of their identity dating back to the Pasteur era. This book details the progress made and milestones that have been set in the science.

  • Bee Products and Their Applications in the Food and Pharmaceutical Industries

    • 1 Edición
    • Dilek Boyacioglu
    • Inglés
    Bee Products and Their Applications in the Food and Pharmaceutical Industries focuses on the health benefits of selected bee products by looking more closely at their pharmacological potentials and therapeutic applications in coping with various diseases. The book explores some of these products, such as royal jelly, propolis and bee venom, which is highly attractive to the food supplement sector due to the biological actions that are proved by scientific studies. Bee products also attract the cosmetics industry by utilizing those products in various applications such as hair products, toothpaste, sunscreen creams, lip balsams, or facial moisturizing creams. Each chapter focuses on a particular health benefit, providing more compact and detailed information about each activity for a specific interest. The mainframe of the book is based on the medicinal and pharmacological functions of bee products, with the therapeutic applications for each bee product supporting the mechanism of action of their biological functions.

  • Aids to the Examination of the Peripheral Nervous System

    • 6 Edición
    • Michael O'Brien
    • Inglés
    For more than 80 years this unique short atlas has been the go-to guide to the examination of patients with lesions of the peripheral nerves and nerve roots – appreciated by generations of students and experienced practitioners alike.First published in its original form in 1943 and updated in its sixth edition by highly respected author Michael O’Brien, this book is the perfect companion for all those involved or caring for patients with peripheral nerve injuries and other neuromuscular disorders. It covers mononeuropathies, peripheral nerve lesions, examination techniques and anatomy of the peripheral nervous system, all illustrated with excellent diagrams and high-quality photographs.Aids to the Examination of the Peripheral Nervous System now comes with the complete electronic version for the first time, for easy anytime, anywhere access.

  • RNA Therapeutics

    The Evolving Landscape of RNA Therapeutics
    • 1 Edición
    • Paloma H. Giangrande + 2 más
    • Inglés
    RNA Therapeutics: The Evolving Landscape of RNA Therapeutics provides a comprehensive overview of RNA therapeutic modalities, from bench-to-bedside, with an emphasis on the increasingly impactful areas of gene therapy, oligonucleotide therapeutics, gene editing and delivery. International leaders in the field examine RNA-based therapeutics tools that have been developed to-date to modulate cellular processes such as transcription, translation and protein function. Approved RNA-based therapies and lessons learned from failed therapies are discussed in-depth, as are evolving advances in RNA biochemical analysis, and similar advances that are enabling clinical application of RNA-based therapies. Later sections discuss delivery technologies, remaining hurdles in research and translation, the therapy development process from the lab to the clinic, and novel RNA-based therapies currently in development.

  • Cancer

    How Lifestyles May Impact Disease Development, Progression, and Treatment
    • 1 Edición
    • Hymie Anisman + 1 más
    • Inglés
    Cancer: How Lifestyles May Impact Disease Development, Progression, and Treatment explores different processes that influence the efficacy of treatments and what lifestyle and behavioral modification options are available to patients to improve therapy responses, with a focus on addressing their strengths and weaknesses. The book discusses mechanisms by which particular lifestyles may affect cancer processes, including various aspects of immune functioning, inflammatory and energy-related processes, reactive oxygen species, hormonal and neurotransmitter mechanisms, the role of neurotrophins, and microbial effects. Considerable attention is devoted to the impact of psychosocial processes that indirectly affect disease occurrence, and to behavioral change methods.

  • Genomic and Precision Medicine

    Oncology
    • 3 Edición
    • Geoffrey S. Ginsburg + 3 más
    • Inglés
    Genomic and Precision Medicine: Oncology, Third Edition focuses on the applications of genome discovery as research points to personalized cancer therapies. Each chapter is organized to cover the application of genomics and personalized medicine tools and technologies to a) Risk Assessment and Susceptibility, b) Diagnosis and Prognosis, c) Pharmacogenomics and Precision Therapeutics, and d) Emerging and Future Opportunities in the field.

  • Encyclopedia of Infection and Immunity

    • 1 Edición
    • Nima Rezaei
    • Inglés
    Encyclopedia of Infection and Immunity, Four Volume Set provides new insights into the interactions between bacteria, fungi, parasites and their hosts. Specific areas of interest include host cellular and immune response to microbes, molecular mechanisms of action of beneficial microbes or host-associated microbial communities, microbial pathogenesis, virulence factors, experimental models of infection, host resistance or susceptibility, and the generation of innate and adaptive immune responses. Comprised of over 200 chapters written and edited by leading experts in the field, this book will serve as a key resource for students, researchers, academics and industry practitioners in the fields of microbiology, immunology, and infectious diseases. More than 100 years after Robert Koch and Louis Pasteur established the microbial etiology of communicable diseases, the field of microbiology is experiencing a second period of rapid growth and expansion, driven by the realization that changes in host-associated microbial communities might be at the root of a broad spectrum of noncommunicable human diseases. These advances follow on the heels of recent progress in high-throughput sequencing technology, which has provided a wealth of information on the human microbiome and its physiological potential.

  • Silicon and Nano-silicon in Environmental Stress Management and Crop Quality Improvement

    Progress and Prospects
    • 1 Edición
    • Hassan Etesami + 5 más
    • Inglés
    Silicon and Nano-silicon in Environmental Stress Management and Crop Quality Improvement: Progress and Prospects provides a comprehensive overview of the latest understanding of the physiological, biochemical and molecular basis of silicon- and nano-silicon-mediate... environmental stress tolerance and crop quality improvements in plants. The book not only covers silicon-induced biotic and abiotic stress tolerance in crops but is also the first to include nano-silicon-mediate... approaches to environmental stress tolerance in crops. As nanotechnology has emerged as a prominent tool for enhancing agricultural productivity, and with the production and applications of nanoparticles (NPs) greatly increasing in many industries, this book is a welcomed resource.

  • Brenner and Stevens’ Pharmacology

    • 6 Edición
    • Craig W. Stevens
    • Inglés
    More detailed than an outlined review but less overwhelming than an encyclopedic reference, Brenner and Stevens’ Pharmacology, 6th Edition, focuses on the essential principles you need to know in a concise, easy-to-understand manner. Authored by Craig W. Stevens, PhD, this highly illustrated introductory text helps you learn and retain key information in pharmacology—taking you from course exams and the USMLE Step 1 right through to clinical practice. New and extensively revised content keeps you up to date with the latest pharmacologic mechanisms and applications.

  • Novel AI and Data Science Advancements for Sustainability in the Era of COVID-19

    • 1 Edición
    • Victor Chang + 4 más
    • Inglés
    Novel AI and Data Science Advancements for Sustainability in the Era of COVID-19 discusses how the role of recent technologies applied to health settings can help fight virus outbreaks. Moreover, it provides guidelines on how governments and institutions should prepare and quickly respond to drastic situations using technology to support their communities in order to maintain life and functional as efficiently as possible. The book discusses topics such as AI-driven histopathology analysis for COVID-19 diagnosis, bioinformatics for subtype rational drug design, deep learning-based treatment evaluation and outcome prediction, sensor informatics for monitoring infected patients, and machine learning for tracking and prediction models. In addition, the book presents AI solutions for hospital management during an epidemic or pandemic, along with real-world solutions and case studies of successful measures to support different types of communities. This is a valuable source for medical informaticians, bioinformaticians, clinicians and other healthcare workers and researchers who are interested in learning more on how recently developed technologies can help us fight and minimize the effects of global pandemics.

  • Sexual Dysfunction in Parkinson's Disease

    • 1 Edición
    • Volumen 162
    • Inglés
    Sexual Dysfunction in Parkinson's Disease, Volume 182, the latest release in the International Review of Neurobiology series, highlights new advances in the field with this new volume presenting interesting chapters on a variety of trending and important topics, including Prevalence, clinical presentations and impact on relationship, Pathophysiology, Scales for assessing sexual dysfunction in Parkinson’s disease, Diagnostic work up: Laboratory and biomarkers, Management strategies, ICD DDS and sex dysfunction, Non-motor fluctuations and sex dysfunction, Exploring Sexual Dysfunction in Care Homes, and The impact of non-motor symptoms burden on sexual functions.

  • Chemical Microbiology Part B

    • 1 Edición
    • Volumen 665
    • Inglés
    Chemical Microbiology, Part B, Volume 665, the latest release in the Methods of Enzymology series, highlights new advances in the field, including comprehensive chapters on the Application of Antibiotic-derived Fluorescent Probes to Bacterial Studies, Metabolomic approaches for enzyme function and pathway discovery in bacteria, Adding a diazo-transfer reagent to culture to generate secondary metabolite probes for click chemistry, Customized Peptidoglycan Surfaces to Investigate Innate Immune Recognition via Surface Plasmon Resonance, Development and application of highly sensitive labeling reagents for amino acids, Bacterial Cell Wall Modification with a Glycolipid Substrate, and much more.

  • Translational Autoimmunity, Volume 3

    Autoimmune Disease Associated with Different Clinical Features
    • 1 Edición
    • Nima Rezaei
    • Inglés
    Translational Autoimmunity: Autoimmune Diseases in Different Clinical Settings addresses autoimmunity and associated conditions, such as aging, infectious diseases, cancer, neurodegeneration, psychological disorders, fertility, inflammatory vascular diseases, and interstitial lung diseases. The book addresses sufficiently basic questions on how the immune system is designed to distinguish self from no self and behave such that it's able to maintain self-tolerance, how does it work in infections, and how it elicits an auto-reactive state and develops self-antigens seen in autoimmune conditions. This is followed by an overview on the genetic and clinical aspects of the spectrum of autoimmune diseases which are broadly categorized into two types of organ specific autoimmune diseases and non-organ specific autoimmune diseases (also known as systemic autoimmune diseases).

  • Medicinal Plants as Anti-infectives

    Current Knowledge and New Perspectives
    • 1 Edición
    • Francois Chassagne
    • Inglés
    Medicinal Plants as Anti-infectives: Current Knowledge and New Perspectives provides comprehensive and updated data on medicinal plants and plant-derived compounds used as antimicrobials in a range of locations (such as the Balkans, Colombia, India, Lebanon, Mali, Pakistan, Southeast Asia, South Africa, and West Africa). It also provides an overview on the most recent innovations and regulations in the field of drug discovery from ethnobotanical sources. This book will help readers to better appreciate the role of plants and phytomedicines as anti-infectives, to better assess the health benefits of plant-derived products, to help implement new methodologies for studying medicinal plants, and to guide future researchers in the field. Medicinal Plants as Anti-infectives: Current Knowledge and New Perspectives is a valuable resource for students, academic scientists, and researchers from the fields of ethnobotany, pharmacy, medicinal chemistry, and microbiology, as well as for professionals working in national or international health agencies, or in pharmaceutical industries.

  • Scientific Advances in Reconstructive Urology and Tissue Engineering

    • 1 Edición
    • Matthias D. Hofer
    • Inglés
    Scientific Advances in Reconstructive Urology and Tissue Engineering is a comprehensive overview of reconstructive urology that spans male and female, pediatric, neuro-urology and trauma. Traditionally, this field has been focused solely on surgical principles with little attention to basic and translational research. However, recent advances in acellular matrices, scaffolds, stem cells and tissue engineering have changed this focus. This publication is the perfect bridge and definitive tome of the advances that will move the translational and basic science of reconstructive urology forward and allow readers to implement the findings in clinical practice. Through the use of both current case studies and future implications, the content bridges the gap from bench to bedside making it the perfect reference for translational benign urology researchers who wish to move the field of reconstructive surgery forward.

  • Experimental Models of Infection, Inflammation and Injury

    • 1 Edición
    • Volumen 168
    • Inglés
    Experimental Models of Infection, Inflammation and Injury, Volume 168 provides step-by-step protocols for scientific researchers to effectively utilize experimental model systems. Chapters in this new release include Induction and Evaluation of Murine T Cell Transfer Colitis, Modelling acute graft-versus-host disease (aGVHD) in murine bone marrow transplantation (BMT) models with MHC disparity, Mouse models of Graft-Versus-Host Disease, Preclinical Model of Multiple Sclerosis: Methods in Autoimmune Demyelination, Preclinical model of Multiple Sclerosis: focal, chemical or demyelination, Investigating demyelination, efficient remyelination and remyelination failure in organotypic cerebellar slice cultures: workflow and practical tips, and more. Other notable sections cover Rheumatoid Arthritis: Methods for Two Murine Models, Induction of Pancreatitis in Mice with Susceptibility to Pancreatic Cancer, Small Animal Models of Thermal Injury, Large Animal Models of Thermal Injury, Small animal models of localized heart irradiation, Methods for Induction and Assessment of Intestinal Permeability in Rodent Models of Radiation Injury, and more.

  • Managing Treatment-Resistant Depression

    Road to Novel Therapeutics
    • 1 Edición
    • Joao L. de Quevedo + 2 más
    • Inglés
    Managing Treatment-Resistant Depression: Road to Novel Therapeutics defines TRD for readers, discussing the clinical and epidemiological predictors, economic burden and neurobiological factors. In addition, staging methods for treatment resistance are fully covered in this book, including serotonin specific reuptake inhibitors, serotonin norepinephrine reuptake inhibitors, other classes of antidepressants, including tricyclic antidepressants and monoamine oxidase inhibitors, augmentation strategies, and newer antidepressant treatments like ketamine and esketamine. In addition, evidence supporting the use of psychotherapies and neuromodulation strategies are also reviewed. Written by top experts in the field, this book is the first of its kind to review all methods of treatment for TRD.

  • Cell Movement in Health and Disease

    • 1 Edición
    • Michael Schnoor + 2 más
    • Inglés
    Cell Movement in Health and Disease brings the several scientific domains related to the phenomena together, establishing a consistent foundation for researchers in this exciting field. The content is presented in four main section. The first explores the foundations of Cell Movement, including overviews of cellular structure, signaling, physiology, motion-related proteins, and the interface with the cellular membrane. The second part covers the biological aspects of cellular movement, starting with chemical and mechanical sensing, describing the types of cell movement, mechanics at cell level, cell physiology, collective behavior, and the connections with the extracellular matrix. The following chapters provide an overview of the molecular machinery involved and cell-type specific movement. The third part of the book is dedicated to the translational aspects of cell movement, highlighting the key conditions associated with cell movement dysfunction, like cell invasion in cancer, wound healing, developmental issues, neurological dysfunctions, and immune response. The final part of the book covers key methods and modeling tools for cell movement research, including predictive mathematical models, in vitro and in vivo methods, biophysical and bioinformatics tools. Cell Movement in Health and Disease is the ideal reference for scientists from different backgrounds converging to expand the understanding of this key cellular process. Cellular and molecular biologists will gain a better understanding of the physical principals operating at cellular level while biophysicist and biomedical engineers will benefit from the solid biology foundation provided by the book.

  • Healthcare Strategies and Planning for Social Inclusion and Development

    Volume 2: Social, Economic, and Health Disparities of Rural Women
    • 1 Edición
    • Basanta Kumara Behera + 2 más
    • Inglés
    Healthcare Strategies and Planning for Social Inclusion and Development: Volume Two: Social, Economic, and Health Disparities of Rural Women examines rural women, particularly in developing countries, and how social and economic constraints they experience impact their ability to advocate for their own health and impede their access to healthcare. This volume discusses the economic and social barriers rural women confront in exercising their right to health care. It explains how geographical isolation, economic instability, healthcare provider shortages, lack of appropriate funding, resource limitations, and lack of health education are just few factors that make rural health care difficult. The book also covers the impact of social isolation on the health needs of rural women which include chronic diseases, mental health, and OB/GYN services as well as how the lack of opportunities for formal education restrict rural women from working outside the household. This volume will be a useful resource to graduate students in public and global health, public health professionals, health and social work researchers, and health policymakers interested in women’s health, especially in developing countries.

  • Biotechnology in Healthcare, Volume 1

    Technologies and Innovations
    • 1 Edición
    • Debmalya Barh
    • Inglés
    Biotechnology in Healthcare, Technologies and Innovations, Volume One presents up-to-date knowledge on the emerging field of biotechnology as applied to the healthcare industry. Sections cover 3D printing, tissue engineering, synthetic biology, nano-biotechnology, omics, precision medicine, gene therapy, vaccine development, predictive healthcare, entrepreneurship, financing, business models, product development and marketing in the sector. This is a valuable source for biotechnologists, bioinformaticians, clinicians and members of biomedical and healthcare fields who need to understand more about the promising developments of the emerging field of biotechnology in healthcare.

  • Defence from Invertebrates to Mammals: Focus on Tonic Immobility

    • 1 Edición
    • Volumen 271
    • Inglés
    Defence from Invertebrates to Mammals: Focus on Tonic Immobility, Volume 273 in the Progress in Brain Research series, highlights new advances in the field. Chapters in this new release include Defensive responses in invertebrates, Introduction to defensive behavior in vertebrates, Neural circuits of fear and defensive behavior, Fear-associated factors modulating TI, Environmental, ecological and methodological factors of TI Modulation, The neuroethological approach to defense in rabbits, Neurophysiological mechanisms of TI, Neuromediators, brain areas and circuits involved in defense responses, Autonomic correlates of defense responses, Neuroendocrine correlates of stress and TI, Pain control during TI and other immobility models, and more.

  • How to Design and Implement Powder-to-Tablet Continuous Manufacturing Systems

    • 1 Edición
    • Fernando Muzzio + 1 más
    • Inglés
    How to Design and Implement Powder-to-Tablet Continuous Manufacturing Systems provides a comprehensive overview on the considerations necessary for the design of continuous pharmaceutical manufacturing processes. The book covers both the theory and design of continuous processing of associated unit operations, along with their characterization and control. In addition, it discusses practical insights and strategies that the editor and chapter authors have learned. Chapters cover Process Analytical Technology (PAT) tools and the application of PAT data to enable distributed process control. With numerous case studies throughout, this valuable guide is ideal for those engaged in, or learning about, continuous processing in pharmaceutical manufacturing.

  • Profiles of Drug Substances, Excipients, and Related Methodology

    • 1 Edición
    • Volumen 47
    • Abdulrahman Al-Majed
    • Inglés
    Profiles of Drug Substances, Excipients, and Related Methodology, Volume 47 covers all aspects of drug development and formulation of drugs, meeting the information needs of the drug development community that are essential to all phases of pharmaceutical development. This updated release includes comprehensive profiles of five drug compounds: Vinpocetine; Loratadine; Ticagrelor; Lodenafil; Danazol. The volume also contains a chapter reviewing “Application of Chemometrics using direct Spectroscopic methods as a QC tool in Pharmaceutical Industry and their Validation.”

  • Textbook of Arterial Stiffness and Pulsatile Hemodynamics in Health and Disease

    • 1 Edición
    • Julio A. Chirinos
    • Inglés
    Textbook of Arterial Stiffness and Pulsatile Hemodynamics in Health and Disease, Two Volume Set covers the principles, physiology, biologic pathways, clinical implications and therapeutics surrounding arterial stiffness and pulsatile hemodynamics, along with a thorough overview of the field. The book presents complex engineering concepts in a way that those in science and medicine can more easily understand. It includes detailed illustrations. Additionally, it presents advanced bioengineering concepts in boxes for readers who wants more in-depth biophysical knowledge. This is a must-have reference for students, researchers and clinicians interested in learning more about this field.

  • Combination Drug Delivery Approach as an Effective Therapy for Various Diseases

    • 1 Edición
    • Prashant Kesharwani
    • Inglés
    Combination Drug Delivery Approach as an Effective Therapy for Various Diseases explores the use of bioengineering tools in combination drug delivery approaches to control various diseases at different clinical stages of synergistic action, varying mechanisms of action, and during the suppression of drug resistance. The book presents fundamental knowledge on the experiential and experimental aspects of drug combination approaches in order to equip rational applications in preventing the emergence of resistance during the treatment of various diseases. It provides a holistic understanding of the principles behind formation, characterization, applications, regulations, toxicity, challenges and future perspectives of combination drug delivery approaches. It will be of interest to researchers and advanced graduate students in pharmaceutical science, chemistry, biology and medicine, as well as pharmaceutical companies and scientific organizations.

  • Guide to Research Techniques in Neuroscience

    • 3 Edición
    • Matt Carter + 3 más
    • Inglés
    Modern neuroscience research is inherently multidisciplinary, with a wide variety of cutting edge new techniques to explore multiple levels of investigation. This Third Edition of Guide to Research Techniques in Neuroscience provides a comprehensive overview of classical and cutting edge methods including their utility, limitations, and how data are presented in the literature. This book can be used as an introduction to neuroscience techniques for anyone new to the field or as a reference for any neuroscientist while reading papers or attending talks.

  • Advances in Agronomy

    • 1 Edición
    • Volumen 173
    • Donald L. Sparks
    • Inglés
    Advances in Agronomy, Volume 173, the latest release in this leading reference on agronomy, contains a variety of updates and highlights new advances in the field, with each chapter written by an international board of authors.

  • Bacterial Fish Diseases

    • 1 Edición
    • Gowhar Hamid Dar + 4 más
    • Inglés
    Bacterial Fish Diseases: Environmental and Economic Constraints will be useful for researchers and academics who need to understand the nature and consequences of bacteria-related disease in fishes. It has in-depth information on the complete genome of various bacterial species and identifies an essential number of virulence genes that affect the pathogenic potential of the bacteria in fish. Users will find the most relevant information derived from the available bacterial genomes concerning virulence and the diverse virulence factors that actively participate in host adherence, colonization and infection, including structural components, extracellular factors, secretion systems, iron acquisition and quorum sensing mechanisms. This reference is beneficial for understanding economic losses due to bacterial pathogens in fish fauna and its impact on the economy. It addition, it provides information on good aquaculture practices and how to scientifically manage aquaculture and fishery sectors.

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