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Elsevier

Libros en Ciencias de la Vida

  • The Microbiome

    • 1 Edición
    • Volumen 176
    • Inglés
    The Microbiome, Volume 176, assembles known facts and provides guidance for their implementation on topics relating to associations between the gut microbiome and personality traits, depression, anxiety, autism, schizophrenia, cognition, dementia and neurodegeneration. Additionally, this volume considers the influence of the maternal microbiome on brain development, with chapters covering Intervention, prevention, and the brain: prebiotics, probiotics, and fecal transplants, The microbiota-gut-brain axis: focus on the fundamental communication pathways, and Microbiome composition and locations.

  • Stress: Genetics, Epigenetics and Genomics

    Volume 4: Handbook of Stress
    • 1 Edición
    • George Fink
    • Inglés
    This fourth volume in the Handbook of Stress series, Stress: Genetics, Epigenetics and Genomics, deals with the influence that genetics, epigenetics, and genomics have on the effects of and responses to stress. Chapters refer to epigenetic mechanisms that involve DNA methylation, histone modification, and/or noncoding RNA-associated gene activation or silencing. There is also coverage of epigenetic mechanisms in stress-related transgenerational transmission of characteristics, and how these may help explain heritability in some complex human diseases.The Handbook of Stress series, comprised of self-contained volumes that each focus on a specific stress area, covers the significant advances made since the publication of Elsevier’s Encyclopedia of Stress (2000 and 2007). Volume 4 is ideal for graduate students, post-doctoral fellows, faculty and clinicians interested in stress genetics, epigenetics and genomics involved in neuroendocrinology, neuroscience, biomedicine, endocrinology, psychology, psychiatry and the social sciences

  • COVID-19

    The Essentials of Prevention and Treatment
    • 1 Edición
    • Jie-Ming Qu + 2 más
    • Inglés
    COVID-19: The Essentials of Prevention and Treatment elaborates on the ethology, pathogenesis, epidemiology, clinical characteristics, treatment principles, rehabilitation and prevention, and prevention and control measures for COVID-19. Aimed at healthcare workers, and written to be a practical guide, six chapters cover the following aspects of COVID-19: respiratory viruses; pathogenesis; case definitions and diagnosis; treatment; prevention and disease control; and prospects for the management and research of respiratory virus infections. This book gives first-hand information on the prevention, control, diagnosis and treatment of COVID-19.COVID-19 was recognized as a pandemic in March 2020 by the World Health Organization. It is a disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Physicians working in China, particularly where the outbreak was first identified in Wuhan, have built up knowledge of prevention and control measures, and diagnosis and treatment of this disease. These insights are now globally relevant. The authors of this book are senior physicians specializing in respiratory diseases, pulmonary diseases and critical care medicine, and are all clinical and scientific research experts working in China, with particular experience in Wuhan.

  • Machine Learning and Other Artificial Intelligence Applications, An Issue of Neuroimaging Clinics of North America

    • 1 Edición
    • Volumen 30-4
    • Reza Forghani
    • Inglés
    This issue of Neuroimaging Clinics of North America focuses on Artificial Intelligence and Machine Learning and is edited by Dr. Reza Forghani. Articles will include: A Brief History of Artificial Intelligence; Evolution of Approaches for Computerized Image Analysis; Overview of Machine Learning Part 1: Classic Approaches; Overview of Machine Learning Part 2: Artificial Neural Networks & Deep Learning; Overview of Natural Language Processing; Artificial Intelligence & Stroke Imaging: An East Coast Perspective; Artificial Intelligence & Stroke Imaging: A West Coast Perspective; Artificial Intelligence Applications for Brain Tumor Imaging; Diverse Applications of Artificial Intelligence in Neuroradiology; Artificial Intelligence Applications for Head and Neck Imaging; Artificial Intelligence Applications for Predictive Analytics and Workflow Optimization; Artificial Intelligence, Advanced Visualization, and 3D Printing; Ethical & Legal Considerations for Artificial Intelligence; Comprehensive (or 360) Artificial Intelligence: Beyond Image Interpretation Alone, and more!

  • Medicinal Plants in Asia and Pacific for Parasitic Infections

    Botany, Ethnopharmacology, Molecular Basis, and Future Prospect
    • 1 Edición
    • Christophe Wiart
    • Inglés
    Medicinal Plants in Asia and Pacific for Parasitic Infections: Botany, Ethnopharmacology, Molecular Basis, and Future Prospect offers an in-depth view into antiprotozoal pharmacology of natural products from medicinal plants in Asia with an emphasis on their molecular basis, cellular pathways, and cellular targets. This book provides scientific names, botanical classifications, botanical description, medicinal uses, chemical constituents and antiprotozoal activity of more than 100 Asian medicinal plants, with high quality original botanical plates, chemical structures, and pharmacological diagrams and lists hundreds of carefully selected references. It also examines the pharmacological and medicinal applications of Asian medicinal plants especially in drug development for protozoan prevention and treatment. Medicinal Plants in Asia and Pacific for Parasitic Infections is a research tool and resource for the discovery of leads for the treatment of protozoal diseases based on interrelated botanical, biochemical, ethnopharmacological... phylogenetic, pharmacological, and chemical information.

  • YY1 in the Control of the Pathogenesis and Drug Resistance of Cancer

    A Critical Therapeutic Target
    • 1 Edición
    • Benjamin Bonavida
    • Inglés
    YY1 Is Pivotal in the Control of the Pathogenesis and Drug Resistance of Cancer: A Critical Therapeutic Target describes the current state-of-the-art of the transcription factor YY1 that is overexpressed in the majority of cancers and a central factor that regulates all of the major features and characteristics of human cancers. This book emphasizes the biochemical, molecular and genetic underlying mechanisms by which YY1 regulates its pro-cancerous activities. In addition, it also describes the role of YY1 in the regulation of tumor cell resistance to conventional chemo and immunotherapies and the important role of inhibiting YY1 in cancer. This book is a valuable source for cancer researchers, oncologists and several members of medical and biomedical field who are interested in understanding further the role of YY1 in cancer.

  • Environmental Epigenetics in Toxicology and Public Health

    • 1 Edición
    • Volumen 22
    • Rebecca Fry
    • Inglés
    Environmental Epigenetics in Toxicology and Public Health provides in-depth discussions of the suite of complex environmental factors shown to impact epigenetic components within the cell, as well as evidence that these epigenetic modifications are tied to early and later life health effects. This book offers a translational research perspective, highlighting both in vivo and human population-based evidence for ties between the environment, the epigenome, and health outcomes, with an emphasis on evidence for transgenerational effects of exposures, as well as developmental windows of susceptibility to environmentally-link... epigenetic effects. This volume in the Translational Epigenetics series aides in the development of new therapeutic options meant to reverse inappropriate epigenetic alterations, helping researchers in their efforts prevent and treat a variety of chronic diseases tied to environmental exposures.

  • Sensory Evaluation Practices

    • 5 Edición
    • Herbert Stone + 2 más
    • Inglés
    Sensory Evaluation Practices, Fifth Edition, presents the latest developments and methods of sensory evaluation, including those on the front end of innovation, consumer acceptance/preferenc... multivariate statistical analysis, discrimination testing, descriptive analysis, sensory claims substantiation for advertising, and information management. Additionally, related social psychological methods, such as laddering, design thinking, emotional profiling, and applications of qualitative and consumer co-creation and immersive techniques are explored. This book will be an ideal reference for sensory professionals, technical managers, product specialists and research directors in the food, beverage, cosmetics, and other consumer products industries of all sizes.

  • Cosmic Genetic Evolution

    • 1 Edición
    • Volumen 106
    • Inglés
    Cosmic Genetic Evolution, Volume 106 in the Advances in Genetics series, highlights new advances in the field, with this new volume presenting interesting chapters on Panspermia, Cometary Panspermia and Origin of Life, The Efficient Lamarckian Spread of Life in the Cosmos, The Sociology of Science and Generality of the DNA/RNA/Protein Paradigm Throughout the Cosmos, The Mutagenic Source and Power of Our Own Evolution, Origin of New Emergent Coronavirus and Candida Fungal Diseases – Terrestrial or Cosmic?, and Future Prospects for Investigation -The Near-Earth Neighborhood and Beyond.

  • Rethinking Food and Agriculture

    New Ways Forward
    • 1 Edición
    • Amir Kassam + 1 más
    • Inglés
    Given the central role of the food and agriculture system in driving so many of the connected ecological, social and economic threats and challenges we currently face, Rethinking Food and Agriculture reviews, reassesses and reimagines the current food and agriculture system and the narrow paradigm in which it operates. Rethinking Food and Agriculture explores and uncovers some of the key historical, ethical, economic, social, cultural, political, and structural drivers and root causes of unsustainability, degradation of the agricultural environment, destruction of nature, short-comings in science and knowledge systems, inequality, hunger and food insecurity, and disharmony. It reviews efforts towards ‘sustainable development’, and reassesses whether these efforts have been implemented with adequate responsibility, acceptable societal and environmental costs and optimal engagement to secure sustainability, equity and justice. The book highlights the many ways that farmers and their communities, civil society groups, social movements, development experts, scientists and others have been raising awareness of these issues, implementing solutions and forging ‘new ways forward’, for example towards paradigms of agriculture, natural resource management and human nutrition which are more sustainable and just. Rethinking Food and Agriculture proposes ways to move beyond the current limited view of agro-ecological sustainability towards overall sustainability of the food and agriculture system based on the principle of ‘inclusive responsibility’. Inclusive responsibility encourages ecosystem sustainability based on agro-ecological and planetary limits to sustainable resource use for production and livelihoods. Inclusive responsibility also places importance on quality of life, pluralism, equity and justice for all and emphasises the health, well-being, sovereignty, dignity and rights of producers, consumers and other stakeholders, as well as of nonhuman animals and the natural world.　　　　

  • Aquaculture Pharmacology

    • 1 Edición
    • Frederick S.B. Kibenge + 2 más
    • Inglés
    Aquaculture Pharmacology is a reliable, up-to-date, "all inclusive" reference and guide that provides an understanding of practical drug information for the aquaculture industry. This book covers the sources, chemical properties, and mechanisms of action of drugs, and the biological systems upon which they act. It covers various drug interactions, therapeutic uses of drugs, as well as legal considerations within the industry as a whole. It presents the four main groups of drugs used in fish, crustaceans and molluscs and includes disinfectants, antimicrobial drugs, antiparasitic agents, and anesthetics, and identifies areas where more research is needed to generate more knowledge to support a sustainable aquaculture industry. With the burgeoning international aquaculture expansion and expanding global trade in live aquatic animals and their products this book is useful to bacteriologists, mycologists, aquaculturists, clinical practitioners in aquatic animal health and all those in industry, government or academia who are interested in aquaculture, fisheries and comparative biology.

  • Handbook of Bioremediation

    Physiological, Molecular and Biotechnological Interventions
    • 1 Edición
    • Mirza Hasanuzzaman + 1 más
    • Inglés
    Handbook of Bioremediation: Physiological, Molecular and Biotechnological Interventions discusses the mechanisms of responding to inorganic and organic pollutants in the environment using different approaches of phytoremediation and bioremediation. Part One focuses specifically on inorganic pollutants and the use of techniques such as metallothionein-assi... remediation, phytoextraction and genetic manipulation. Part Two covers organic pollutants and consider topics such as plant enzymes, antioxidant defense systems and the remediation mechanisms of different plant species. This comprehensive volume is a must-read for researchers interested in plant science, agriculture, soil science and environmental science. The techniques covered in this book will ensure scientists have the knowledge to practice effective bioremediation techniques themselves.

  • Human Physiology in Extreme Environments

    • 2 Edición
    • Hanns-Christian Gunga
    • Inglés
    Human Physiology in Extreme Environments, Second Edition, offers evidence on how human biology and physiology is affected by extreme environments, also highlighting technological innovations that allow us to adapt and regulate environments. Covering a broad range of extreme environments, including high altitude, underwater, tropical climates, desert climates, arctic climates and space travel, the book also includes case studies that can be used to illustrate practical application. Graduate students, medical students and researchers will find this to be an interesting, informative and useful resource for human physiology, environmental physiology and medical studies.

  • Manual of Percutaneous Coronary Interventions

    A Step-by-Step Approach
    • 1 Edición
    • Emmanouil Brilakis
    • Inglés
    Manual of Percutaneous Coronary Interventions: A Step by Step Approach is a practical, easy to read reference guide on how to perform percutaneous coronary. Written by recognized experts in the field, this reference compiles the necessary steps, lists pitfalls to watch out for, and provides tactics on troubleshooting percutaneous coronary interventions. Written to bring a practical and easy to read approach, this book is perfect for interventional cardiologists, interventional and general cardiology fellows, cardiology researchers, physicians, cardiac catheterization laboratory personnel, technical staff, industry professionals and anyone interested in understanding the cutting-edge and rapidly evolving field of coronary PCI.

  • Food Security and Nutrition

    • 1 Edición
    • Charis M. Galanakis
    • Inglés
    Food and nutrition security - identified via availability, access, utilization, and stability - and transitions to sustainable food systems are major discourses in the agro-food arena, as many countries today experience different forms of malnutrition simultaneously, such as child undernutrition, anemia among women, and adult obesity. Meanwhile, the triple burden of malnutrition (undernutrition, overnutrition, and micronutrient deficiency) is still widespread. Food Security and Nutrition explores integrated, context-specific approaches to food security challenges, emphasizing nutrition security as an integral component and addressing the implications of food content to food and nutrition security policies. Providing insight into these challenges through agricultural, policy, nutritional, geographic and sustainability lenses, Food Security and Nutrition is a valuable reference for food scientists and nutrition researchers working in food supply, food security, and nutrition security, and policy makers, investors, and other decision-makers seeking to address food insecurity around the world.

  • Application of Nano/Microencapsulated Ingredients in Food Products

    • 1 Edición
    • Volumen 6
    • Inglés
    Application of Nano/Microencapsulat... Ingredients in Food Products, a volume in the Nanoencapsulation in the Food Industry series, presents applications of nano/micro-encapsula... ingredients such as vitamins, minerals, flavors, colorants, enzymes, probiotics antioxidants and many other bioactive components in different groups of food products. Each chapter explores nano/microencapsulat... ingredients in food products, including beverages, cereal flours and bakery products, meat, oils and fats, salt, spices and seasonings, functional supplements, and in chewing gum. In addition, the book explores active food packaging and edible coatings with nano/microencapsulat... ingredients. Authored by a team of global experts in the fields of nano and microencapsulation of food, nutraceutical and pharmaceutical ingredients, this title is of great value to those engaged in the various fields of nanoencapsulation.

  • Data Analytics in Biomedical Engineering and Healthcare

    • 1 Edición
    • Kun Chang Lee + 3 más
    • Inglés
    Data Analytics in Biomedical Engineering and Healthcare explores key applications using data analytics, machine learning, and deep learning in health sciences and biomedical data. The book is useful for those working with big data analytics in biomedical research, medical industries, and medical research scientists. The book covers health analytics, data science, and machine and deep learning applications for biomedical data, covering areas such as predictive health analysis, electronic health records, medical image analysis, computational drug discovery, and genome structure prediction using predictive modeling. Case studies demonstrate big data applications in healthcare using the MapReduce and Hadoop frameworks.

  • Advances in Food Security and Sustainability

    • 1 Edición
    • Volumen 5
    • Marc J. Cohen
    • Inglés
    Advances in Food Security and Sustainability, Volume Five, takes a scientific look at the challenges, constraints and solutions necessary to maintain a healthy and accessible food supply in different communities. This ongoing series addresses a wide range of issues on food sustainability and security, exploring challenges related to protecting environmental resources while also meeting human nutritional requirements.

  • Molecular Nutrition

    Mother and Infant
    • 1 Edición
    • Manlio Vinciguerra + 1 más
    • Inglés
    Molecular Nutrition: Mother and Infant presents the impact of diet in early life stages, from pre-conception, throughout pregnancy, and to the infant. The book covers the molecular biology of the cell, genetic machinery and its function, general coverage on diet and nutrition, pregnancy, placenta, weight gain, breast milk, feeding practices, gestational disease, glucose metabolism, immunity, vitamins and minerals. Other topics discusses include fetal programming, bioactive compounds, amino acids, intrauterine growth, one carbon metabolism, overnutrition, genetic risk factors, polymorphisms, folic acid genes, DNA methylation, genes involved in lipid metabolism, microRNAs, epigenetics, transcriptomics and micro RNA. This book will be a welcomed reference for research scientists and practitioners, including nutritionists and dieticians.

  • Recent Developments in Applied Microbiology and Biochemistry

    Volume 2
    • 1 Edición
    • Viswanath Buddolla
    • Inglés
    Recent Developments in Applied Microbiology and Biochemistry, Vol. 2, provides a comprehensive treatment and understanding on application oriented microbial concepts, giving readers insights into recent developments in microbial biotechnology and medical, agricultural and environmental microbiology.

  • Clinical Perspectives and Targeted Therapies in Apoptosis

    Drug Discovery, Drug Delivery, and Disease Prevention
    • 1 Edición
    • Rupinder K. Sodhi + 1 más
    • Inglés
    Clinical Perspectives and Targeted Therapies in Apoptosis: Drug Discovery, Drug Delivery, and Disease Prevention provides comprehensive coverage, from basic cell biology, to modern assessment techniques for apoptosis in all major disease areas. Chapters provide an introduction to the fundamentals of cell biology, biochemical mechanisms, and the pathophysiological consequences of apoptosis. In addition, the book covers the tools and techniques used to quantify apoptosis and the significance of apoptosis in drug discovery, drug delivery, and its applications in disease prevention. Finally, the book provides a comprehensive compilation of the apoptosis targeting drugs that recently underwent clinical trials. This combination of fundamentals, along with applications in drug discovery, drug delivery, and clinical research make this book a useful resource for those in both academia and industry who are engaged in pharmaceutical, biomedical and biotechnology research.

  • Controlled Release Fertilizers for Sustainable Agriculture

    • 1 Edición
    • F.B Lewu + 3 más
    • Inglés
    Controlled Release Fertilizers for Sustainable Agriculture provides a comprehensive examination of precision fertilizer applications using the 4-R approach—the right amount of fertilizer at the right time to the right plant at the correct stage of plant growth. This volume consolidates detailed information on each aspect of controlled release fertilizers, including up-to-date literature citations, the current market for controlled release fertilizers and patents. Presenting the tremendous advances in experimental and theoretical studies on sustainable agriculture and related areas, this book provides in-depth insight into state-of-the-art controlled release mechanisms of fertilizers, techniques, and their use in sustainable agriculture. Conventional release mechanisms have historically meant waste of fertilizers and the adverse effects of that waste on the environment. Controlled release delivery makes significant strides in enhancing fertilizer benefit to the target plant, while protecting the surrounding environment and increasing sustainability.

  • Microbe Mediated Remediation of Environmental Contaminants

    • 1 Edición
    • Ajay Kumar + 3 más
    • Inglés
    Microbe Mediated Remediation of Environmental Contaminants presents recent scientific progress in applying microbes for environmental management. The book explores the current existing practical applications and provides information to help readers develop new practices and applications. Edited by recognized leaders in the field, this penetrating assessment of our progress to date in deploying microorganisms to the advantage of environmental management and biotechnology will be widely welcomed by those working in soil contamination management, agriculture, environment management, soil microbiology, and waste management. The polluting effects on the world around us of soil erosion, the unwanted migration of sediments, chemical fertilizers and pesticides, and the improper treatment of human and animal wastes have resulted in serious environmental and social problems around the world, problems which require us to look for solutions elsewhere than established physical and chemical technologies. Often the answer lies in hybrid applications in which microbial methods are combined with physical and chemical ones. When we remember that these highly effective microorganisms, cultured for a variety of applications, are but a tiny fraction of those to be found in the world around us, we realize the vastness of the untapped and beneficial potential of microorganisms.

  • Actin Cytoskeleton in Cancer Progression and Metastasis - Part B

    • 1 Edición
    • Volumen 356
    • Inglés
    Actin Cytoskeleton in Cancer Progression and Metastasis (Part B), Volume 356 in the International Review of Cell and Molecular Biology series, provides an overview on the roles of the actin cytoskeleton and its key structural regulators, including WASp, Paxillin, Myosin, Testin, L-Plastin and profilin, and in central processes underlying cancer progression and metastasis, such as changes in cell morphology and gene expression, acquisition of migratory and invasive capabilities, and evasion from the immune response. Specific chapters in this release cover Actin dynamics during tumor cell dissemination, Actin cytoskeleton remodeling during cancer cell migration, Cytoskeletal Mechanics Drives Heterogeneity in Epithelial Ovarian Cancer, and much more.

  • Vertebrate Endocrinology

    • 6 Edición
    • David O. Norris + 1 más
    • Inglés
    Vertebrate Endocrinology, Sixth Edition, provides a comprehensive, up-to-date treatment of the endocrine system for college and university students as well as researchers. This book is logically arranged, easily comprehended, and well-illustrated. It covers traditional hormone-based systems and introduces all forms of chemical communication, their implications for the health of humans, domesticated, and wild vertebrates. Written by two experts who have completed extensive research in comparative vertebrate endocrinology with an emphasis on natural and anthropogenic environmental factors influencing endocrine systems. Collectively, the authors have taught courses in endocrinology at the undergraduate and graduate level for more than 60 years. After first publishing in 1985, Vertebrate Endocrinology, Sixth Edition, continues to serve as an important resource for graduate students and advanced undergraduates in the biological sciences, animal sciences, and veterinary sciences. Endocrine researchers will also benefit from the book’s relevance in the areas of comparative, veterinary, and mammalian endocrinology.

  • Marcus and Feldman's Osteoporosis

    • 5 Edición
    • David W. Dempster + 3 más
    • Inglés
    Marcus and Feldman's Osteoporosis, Fifth Edition, is the most comprehensive, authoritative reference on this disease. Led by a new editorial team, this fifth edition offers critical information on reproductive and hormonal risk factors, new therapeutics, ethnicity, nutrition, therapeutics, management and economics, comprising a tremendous wealth of knowledge in a single source not found elsewhere. Written by renowned experts in the field, this two-volume reference is a must-have for biomedical researchers, research clinicians, fellows, academic and medical libraries, and any company involved in osteoporosis drug research and development.

  • Protein Biosynthesis Interference in Disease

    • 1 Edición
    • Elena L. Paley
    • Inglés
    Protein Biosynthesis Interference in Disease offers a thorough discussion and overview of protein biosynthesis interference, its mechanisms of action, and influence over disease processes. This book examines the role of protein biosynthesis interference in Alzheimer’s and other neurodegenerative conditions, cancer and inflammatory disorders, with specific attention paid to the biochemical dynamics of tryptamine, biogenic amines and aminoacyl-tRNA synthetases in these pathologies. Methods of regulating protein translation and interference mechanisms, including gene therapy, are presented, empowering biochemists, molecular biologists, disease researchers, and health professionals to understand the underlying factors of protein disease and improve patient outcomes.

  • Natural Bioactive Compounds

    Technological Advancements
    • 1 Edición
    • Rajeshwar P. Sinha + 1 más
    • Inglés
    Natural Bioactive Compounds: Technological Advancements deals with the latest breakthroughs in the field of screening, characterization and novel applications of natural bioactive compounds from diverse group of organisms ranging from bacteria, viruses, cyanobacteria, algae, fungi, bryophytes, higher plants, sponges, corals and fishes. Written by some of the most reputed scientists in the field, this book introduces the reader to strategies and methods in the search for bioactive natural products. It is an essential read for researchers and students interested in bioactive natural products, their biological and pharmacological properties, their possible use as chemopreventive or chemotherapeutic agents, and other future potential applications.

  • Microalgae

    Cultivation, Recovery of Compounds and Applications
    • 1 Edición
    • Charis M. Galanakis
    • Inglés
    Microalgae: Cultivation, Recovery of Compounds and Applications supports the scientific community, professionals and enterprises that aspire to develop industrial and commercialized applications of microalgae cultivation. Topics covered include conventional and emerging cultivation and harvesting techniques of microalgae, design, transport phenomena models of microalgae growth in photobioreactors, and the catalytic conversion of microalgae. A significant focus of the book illustrates how marine algae can increase sustainability in industries like food, agriculture, biofuel and bioprocessing, among others. This book is a complete reference for food scientists, technologists and engineers working in the bioresource technology field. It will be of particular interest to academics and professionals working in the food industry, food processing, chemical engineering and biotechnology.

  • Handbook of Diagnostic Endocrinology

    • 3 Edición
    • William E. Winter + 3 más
    • Inglés
    The clinical laboratory plays a critical role in the diagnosis and management of endocrine and related metabolic disorders, which are leading causes of morbidity and mortality in children and adults. The Handbook of Diagnostic Endocrinology, Third Edition, provides a ready reference for the evaluation, diagnosis, and monitoring of such disorders. This revision incorporates translational medicine, connecting what clinicians need to know with those in research providing a clinical context to which they can relate their molecular findings. This book solves the needs of clinicians and researchers by bringing together in one book endocrinology at the molecular and clinical levels. As the intricacies of intracellular signaling have become better understood, states of hormone resistance are now increasingly recognized. The most common endocrinopathy in westernized countries, the metabolic syndrome, results, to a large extent, from insulin resistance. The complexity of the circulating forms of various hormones are acknowledged in this revision.

  • Waterborne Pathogens

    Detection Methods and Applications
    • 2 Edición
    • Helen Bridle
    • Inglés
    Waterborne Pathogens: Detection Methods and Applications, Second Edition, gives an overview of advanced and emerging technologies in the detection of a range of waterborne pathogens. In addition, the book presents existing methodologies, highlights where improvements can be made, includes applications, and touches on the ways in which new technologies can be applied in water management. Finally, the book addresses issues of sample preparation (from sampling, to concentration and enrichment), a key stage in any detection protocol.

  • Fungi Bio-prospects in Sustainable Agriculture, Environment and Nano-technology

    Volume 1: Fungal Diversity of Sustainable Agriculture
    • 1 Edición
    • Vijay Kumar Sharma + 3 más
    • Inglés
    Fungi bio-prospects in sustainable agriculture, environment and nanotechnology　is a three-volume series that has been designed to explore the huge potential of the many diverse applications of fungi to human life. The series unveils the latest developments and scientific advances in the study of the biodiversity of fungi, extremophilic fungi, and fungal secondary metabolites and enzymes, while also presenting cutting-edge molecular tools used to study fungi. Readers will learn all about the recent progress and future potential applications of fungi in agriculture, environmental remediation, industry, food safety, medicine, and nanotechnology. Volume 1 will cover the biodiversity of fungi and the associated biopotential applications. This volume offers insights into both basic and advanced biotechnological applications in human welfare and sustainable agriculture. The chapters shed light on the different roles of fungi as a bio-fertilizer, a bio-control agent, and a component of microbial inoculants. They also focus on the various applications of fungi in bio-fuel production, nano-technology, and in the management of abiotic stresses such as drought, salinity, and metal toxicity.　

  • Immunotherapy in Resistant Cancer: From the Lab Bench Work to Its Clinical Perspectives

    • 1 Edición
    • Jorge Morales-Montor + 1 más
    • Inglés
    Immunotherapy in Resistant Cancer: From the Lab Bench Work to Its Clinical Perspectives provides high level knowledge on detailed mechanisms of actions and biological interactions of different immune drugs, with an aim of offering researchers and clinicians cutting-edge therapies to overcome drug resistance. The book explains the latest immunotherapies for different types of cancer, helping users carry out research projects or create alternatives for drug development in the pharmaceutical industry. Topics discussed include the relationship between immunotherapy and macrophages, immune checkpoints in different types of cancer, immune cocktails in solid tumors, and immune-phenotyping. Additionally, the book presents basic and clinical data on immunoresistance and glycosylation. This book is a valuable source for cancer researchers, medical doctors, clinicians and members of the biomedical field who must understand certain mechanisms to fight cancer that is resistant to immunotherapy.

  • Emery and Rimoin’s Principles and Practice of Medical Genetics and Genomics

    Metabolic Disorders
    • 7 Edición
    • Reed E. Pyeritz + 2 más
    • Inglés
    For decades, Emery and Rimoin’s Principles and Practice of Medical Genetics and Genomics has served as the ultimate resource for clinicians integrating genetics into medical practice. With nearly 5,000 pages of detailed coverage, contributions from over 250 of the world’s most trusted authorities in medical genetics, and a series of 11 volumes available for individual sale, the Seventh Edition of this classic reference includes the latest information on seminal topics such as prenatal diagnosis, genome and exome sequencing, public health genetics, genetic counseling, and management and treatment strategies to complete its coverage of this growing field for medical students, residents, physicians, and researchers involved in the care of patients with genetic conditions. This comprehensive yet practical resource emphasizes theory and research fundamentals related to applications of medical genetics across the full spectrum of inherited disorders and applications to medicine more broadly. In Metabolic Disorders, leading physicians and researchers thoroughly examine medical genetics as applied to a range of metabolic disorders, with emphasis on understanding the genetic mechanisms underlying these disorders, diagnostic approaches, and therapeutics that make use of current genomic technologies and translational studies. Here genetic researchers, students, and health professionals will find new and fully revised chapters on the genetic basis of body mass, amino acid, carbohydrate, iron, copper, lipo protein, and lipid metabolic disorders, as well as organic acidemias, fatty acid oxidation, and peroxisome disorders among others. With regular advances in genomic technologies propelling precision medicine into the clinic, Emery and Rimoin’s Principles and Practice of Medical Genetics and Genomics: Seventh Edition bridges the gap between high-level molecular genetics and practical application and serves as an invaluable clinical tool for health professionals and researchers.

  • Sex Differences in Neurology and Psychiatry

    • 1 Edición
    • Volumen 175
    • Inglés
    Sex Differences in Neurology and Psychiatry, Volume 175, addresses this important issue by viewing major neurological and psychiatric conditions through the lens of sexual dimorphism, providing an entirely novel approach to understanding vulnerability factors, as well as potential new treatment strategies in several common neuropsychiatric disorders. The handbook comprises four major sections: (1) Introduction to sex differences in neuroanatomy and neurophysiology, (2) Description of the impact of genetic, epigenetic, sex hormonal and other environmental effects on cerebral sex dimorphism, (3) Review of sex differences in neurologic disorders, and (4) Review of sex differences in psychiatric disorders.

  • Gastroparesis

    Pathophysiology, Clinical Presentation, Diagnosis and Treatment
    • 1 Edición
    • Richard Mccallum + 3 más
    • Inglés
    Gastroparesis: Pathophysiology, Clinical Presentation, Diagnosis and Treatment is a reference book providing a centralized source of data on gastroparesis collected over the last decade. Contents include the pathophysiology, clinical presentation, diagnostic recommendations and treatment options for gastroparesis. The reference is split into broad subsections, with the strategy of first focusing on the key features of the disease and then turning to controversies, recent developments, patient support resources, the spectrum of treatment – including medical and surgical - and future directions. Chapters will include coverage of important topics like autonomic neuropathy, the brain-gut axis, potential pathophysiological advances at the cellular level, diagnostic and therapeutic options specifically targeted at the pylorus, and the evaluation of the female predominance in gastroparesis. This is a must-have resource for scientists looking to find the next step in their research as well as healthcare professionals ranging from Gastroenterologists to Internists, Surgeons, Nutritionists, Psychiatrists, and Psychologists, Residents and Medical Students who struggle with how to optimally take care of their gastroparetic patients.

  • Mosby's Advanced Pharmacy Technician

    • 1 Edición
    • Karen Davis
    • Inglés
    Take your career to the next level with Mosby’s Advanced Pharmacy Technician: Principles and Practice! Beginning with an exploration of expanding roles for the pharmacy technician, this resource includes coverage of leadership, management, and technical skills to support career progression and preparation for the new Advanced Pharmacy Technician certification credential. Case studies, critical thinking exercises, chapter quizzes, and a sample exam provide ample opportunities for skills assessment. A perfect companion to Mosby’s Pharmacy Technician, this text provides you with the knowledge and tools needed to take charge of your career in the fast-paced and exciting field of pharmacy technology! (Mosby’s Pharmacy Technician sold seperately.)

  • Computational Modelling of Biomechanics and Biotribology in the Musculoskeletal System

    Biomaterials and Tissues
    • 2 Edición
    • Z Jin + 2 más
    • Inglés
    Computational Modelling of Biomechanics and Biotribology in the Musculoskeletal System: Biomaterials and Tissues, Second Edition reviews how a wide range of materials are modeled and applied. Chapters cover basic concepts for modeling of biomechanics and biotribology, the fundamentals of computational modeling of biomechanics in the musculoskeletal system, finite element modeling in the musculoskeletal system, computational modeling from a cells and tissues perspective, and computational modeling of the biomechanics and biotribology interactions, looking at complex joint structures. This book is a comprehensive resource for professionals in the biomedical market, materials scientists and biomechanical engineers, and academics in related fields. This important new edition provides an up-to-date overview of the most recent research and developments involving hydroxyapatite as a key material in medicine and its application, including new content on novel technologies, biomorphic hydroxyapatite and more.

  • iPSCs from Diverse Species

    • 1 Edición
    • Alexander Birbrair
    • Inglés
    The series Advances in Stem Cell Biology is a timely and expansive collection of comprehensive information and new discoveries in the field of stem cell biology. iPSCs from Diverse Species, Volume 2 addresses how induced pluripotent stem cells (iPSCs) can be derived from different species. The volume teaches the reader about modern state-of-the-art methodologies to derive iPSCs from distinct species. This volume will cover how to derive iPSCs from species like nonhuman primates, horses, dogs, pigs, rats, rabbits, and others. It also discusses the importance of iPSCs in species conservation. Detailed description on methods used to obtain iPSCs from humans and other species expands the knowledge and understanding of stem cell biology and provides a potent tool to model diseases. The volume is written for researchers and scientists in stem cell biology, and regenerative medicine and is contributed by world-renowned authors in the field.

  • Elephants Under Human Care

    The Behaviour, Ecology, and Welfare of Elephants in Captivity
    • 1 Edición
    • Paul A. Rees
    • Inglés
    This book draws together, for the first time, the published research on the behaviour, ecology and welfare of elephants living in zoos, circuses, logging camps and other captive environments in a single comprehensive volume. It takes a multi-disciplinary approach, considering the work of zoo biologists, animal behaviour and welfare scientists, veterinarians, philosophers, zoo educators, tourism specialists, conservation biologists, lawyers and others with a professional interest in elephants. Elephants under Human Care: The Behaviour, Ecology, and Welfare of Elephants in Captivity is a valuable resource for zoo biology and animal welfare researchers. It is also useful for students and zoo professionals and managers looking for a comprehensive guide to current research on captive elephants. Although not intended as a husbandry manual, the book discusses some of the elephant welfare standards developed by the Association of Zoos and Aquariums (AZA) and the British and Irish Association of Zoos and Aquariums (BIAZA) and their relationship to current knowledge of captive elephants.

  • Glaucoma: A Neurodegenerative Disease of the Retina and Beyond Part B

    • 1 Edición
    • Volumen 257
    • Giacinto Bagetta + 1 más
    • Inglés
    Glaucoma: A Neurodegenerative Disease of the Retina and Beyond Part B, Volume 257, the latest release in the Progress in Brain Research series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Topics covered in this new release include Glaucoma neurodegeneration and myopia, Links between obstructive sleep apnea and glaucoma neurodegeneration, Artificial intelligence and deep learning in glaucoma: Current state and future prospects, Brain networks reorganization and functional disability in glaucoma, Advanced vascular examinations of the retina and optic nerve head in glaucoma, and much more.

  • Advances in Immunology

    • 1 Edición
    • Volumen 147
    • Inglés
    Advances in Immunology, Volume 147, the latest release in a long-established and highly respected publication, presents current developments and comprehensive reviews in immunology. Chapters in this new release include Histone deacetylases as targets in autoimmune and autoinflammatory diseases, The advancing area of the mechanisms involved in the evolution of HIV-1 neutralizing antibodies, T cells in latent viral infections, Communications of dendritic cells with T cells and NK cells in cancerous tissues, Mechanism and Regulation of Class Switch Recombination by IgH transcriptional Control Elements, IL-2 partial agonist, Preserving Immune Homeostasis with A20, The design of vaccine strategies to elicit HIV-1 broadly neutralizing antibodies.

  • Neurocognitive Development: Disorders and Disabilities

    • 1 Edición
    • Volumen 174
    • Inglés
    This is one volume of a two-volume work on neurocognitive development, focusing separately on normative and non-normative development. The disorders and disabilities volume focuses on disorders of intellectual abilities, language, learning memory as well as psychiatric developmental disorders. The developmental aspects of neurological diseases in children is also covered. Chapters discuss when and how these disorders develop, the genetics and neurophysiology of their operation, and their evaluation and assessment in clinical practice. Assessment, treatment, and long-term outcome are provided as well as advances in methods and tools for assessment. This book will serve as a comprehensive reference to researchers in cognitive development in neuroscience, psychology, and medicine, as well as to clinicians and allied health professionals focused on developmental disabilities (child neurologists, pediatric neuropsychologists, child psychiatrists, speech and language therapists, and occupational therapists.)

  • The Neuroscience of Parkinson's Disease

    • 1 Edición
    • Colin R. Martin + 1 más
    • Inglés
    The Neuroscience of Parkinson’s Disease (two volume set) provides a single source of material covering different scientific domains of neuropathology underlying this condition. The book covers a wide range of subjects and unravels the complex relationships between genetics, molecular biology, pharmaceutical chemistry, neurobiology, imaging, assessments, and treatment regimens. The book also fills a much-needed gap as a "one-stop" synopsis of everything to do with the neurology and neuroscience related to Parkinson’s disease—from chemicals and cells to individuals. It is an invaluable resource for neuroscientists, neurologists, and anyone in the field.

  • The Neuroscience of Dementia

    • 1 Edición
    • Colin R. Martin + 1 más
    • Inglés
    The Neuroscience of Dementia brings together different fields of dementia research into a single book, covering a wide range of subjects, including Alzheimer’s disease, Lewy body dementia, mixed dementia, vascular dementia, physical activity, risk factors, mortality, biomarkers, SPECT, CT, MRI, questionnaires, nutrition, sleep, delirium, hearing loss, agitation, aggression, delusions, anxiety, depression, hallucinations, psychosis, senile plaques, tau and amyloid-beta, neuroinflammation, molecular biology, and more. This foundational, comprehensive book compiles the latest understanding on all forms of dementia and their common features in a single source. It is an invaluable resource for neuroscientists, neurologists, and anyone in the field.

  • The Ethics of Everyday Medicine

    Explorations of Justice
    • 1 Edición
    • Erwin B. Montgomery Jr.
    • Inglés
    Ethics of Everyday Medicine: Explorations of Justice examines and analyses the relatively unexplored domain of ethics involved in the everyday practice of medicine. From the author’s clinical experience, virtually every decision made in the day-to-day practice of medicine is fundamentally an ethical question, as virtually every decision hinge on some value judgment that goes beyond the medical facts of the matter. The first part of the book is devoted to medical decision cases in several areas of medicine. These cases highlight elements of the current healthcare ecosystem, involving players other than the physician and patient. Insurers (private, commercial, and governmental), administrators, and regulators’ perspectives are surfaced in point of care case analysis. Part two contributes to the development of actionable tools to develop better ethical systems for the everyday practice of medicine by providing a critical analysis of Reflective Equilibrium and ethical induction from the perspective of logic and statistics. The chapter on Justice discusses the neurophysiological representations of just and unjust behaviours. The chapter on Ethical Theories follows, describing the epistemic conundrum, principlism, reproducibility, abstraction, chaos and complexity. The following chapter approaches ethical decisions from the logic and statistic perspectives. The following chapter, The Patient as Parenthetical, the author discusses patient-centric ethics, and the rise of business- and government-cetric ethics. The final chapter, A Framework to Frame the Questions for Explore Further, proposes a working framework to deal with current ethical issues. Ethics of everyday Medicine: Explorations of Justice acknowledges that there are no answers yet to the ethical dilemmas that confront the everyday practice of medicine, but proposes a framework for deeper analysis and action. This reading would be useful to all healthcare professionals. Regulators and policy makers could also benefit from understanding how the complex healthcare environment influences medical decisions at point of care.

  • Endocrinology of Aging

    Clinical Aspects in Diagrams and Images
    • 1 Edición
    • Emiliano Corpas + 4 más
    • Inglés
    According to the United Nations, the number of people aged 60 years or over in the world is projected to be 1.4 billion in 2030 and 2.1 billion in 2050. Endocrinologists and other clinicians face the challenge of caring for the elderly. To do so, they need to incorporate geriatric principles into their clinical practice. Endocrinology of Aging: Clinical Aspects in Diagrams and Images presents chapters in a way that allows the reader to incorporate concepts and main facts of complex subjects in a visual way. As the global population becomes older, the need for a deeper understanding of geriatric pathology increases, and with it, the access to educational resources for the endocrinology and metabolism of aging.

  • Genetically Modified Plants

    Assessing Safety and Managing Risk
    • 2 Edición
    • Roger Hull + 2 más
    • Inglés
    Genetically Modified Plants, Second Edition, provides an updated roadmap and science-based methodology for assessing the safety of genetic modification technologies, as well as risk assessment approaches from regulators across different agroecosystems. This new edition also includes expanded coverage of technologies used in plant improvement, such as RNA-dependent DNA methylation, reverse breeding, agroinfiltration, and gene-editing technologies such as CRISPR and TALENS. This book is an essential resource for anyone interested in crop improvement, including students and researchers, practitioners in regulatory agencies, and policymakers involved in plant biotechnology risk assessment.

  • Flavin-Dependent Enzymes: Mechanisms, Structures and Applications

    • 1 Edición
    • Volumen 47
    • Inglés
    The Enzymes, Volume 47, highlights new advances in the field, with this new volume presenting interesting chapters on The Multipurpose Family of Oxidases, Vanillyl alcohol oxidase, Choline oxidases, Aryl alcohol oxidase, D- and L-amino acid oxidases, Sugar oxidases, Phenolic Compounds hydroxylases, Baeyer-Villiger Monooxygenases, Flavin-dependent halogenases, Flavin-dependent dehalogenases, Styrene Monooxygenases, Bacterial luciferases, Cellobiose Dehydrogenases, Prenylated flavoenzymes, Ene-reductases, Flavoenzymes in Biocatalysis.

  • Evolutionary Diversity as a Source for Anticancer Molecules

    • 1 Edición
    • Akhileshwar Kumar Srivastava + 3 más
    • Inglés
    Evolutionary Diversity as a Source for Anticancer Molecules discusses evolutionary diversity as source for anticancer agents derived from bacteria, algae, bryophytes, pteridophytes, and gymnosperms. The book goes over the isolation of anticancer agents and the technologyenabled screening process used to develop anticancer drugs. The book also includes discussion of the nutraceuticals and natural productsderived from invertebrates that can be used as part of cancer treatment. Evolutionary Diversity as a Source for Anticancer Molecules also deals with some of the current challenges in the prevention of cancer as well as the side effects of conventional drugs used for cancer patients.This book is a valuable resource for cancer researchers, oncologists, biotechnologists, pharmacologists, and any member of the biomedicalfield interested in understanding more about natural products with anticancer potential.

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