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Elsevier

Libros en Ciencias de la Vida

  • Glaucoma: A Neurodegenerative Disease of the Retina and Beyond: Part A

    • 1 Edición
    • Volumen 256
    • Inglés
    Glaucoma: A Pancitopatia of the Retina and Beyond, Volume 257, the latest release in the Progress in Brain Research series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Chapters in this volume include the Genetics of glaucoma, Artificial intelligence and deep learning in glaucoma detection and monitoring, The role of commensal microflora-induced T cells responses in glaucoma neurodegeneration, Retinal cell death in experimental glaucoma, Experimental and clinical evidence on the neuroprotective properties of Citicoline in glaucoma, Glaucoma neurodegeneration and myopia, Neuronal regeneration with pluripotent stem cells in glaucoma, and more.

  • Medicinal Natural Products: A Disease-Focused Approach

    • 1 Edición
    • Volumen 55
    • Inglés
    Medicinal Natural Products: A Disease-Focused Approach, Volume 55 in the Annual Reports in Medicinal Chemistry series, highlights the applications of natural products as medicines or prospective medicinal leads for the treatment of various human ailments. Each chapter covers a particular disease area or medical condition, with chapters in this new release covering Medicinal Natural Products – An Introduction, Anticancer Natural Products, Antimicrobial Natural Products, Antimalarial and Antiparasitic Natural Products, Anti-inflammatory Natural Products, Neuroprotective Natural Products, Hepatoprotective Natural Products, Nephroprotective Natural Products, Cancer Chemopreventive Natural Products, Antipsoriatic Natural Products, Medicinal Natural Products in Osteoporosis, Antidiabetic Natural Products, Anti-obesity Natural Products, and much more.

  • Millets and Pseudo Cereals

    Genetic Resources and Breeding Advancements
    • 1 Edición
    • Mohar Singh + 1 más
    • Inglés
    Millets and Pseudo Cereals is the first comprehensive resource to focus on the potential crop improvements through genetic enhancements. The choice of food crop for a region is primarily determined by the conditions of climate and soil. Once labelled as orphan crops, millets and pseudo-cereals are now known as miracle grains due to their adaptation to harsh conditions and high nutritional quality. Small millets and pseudo-cereals are now seen to occupy special niches through their ability to adapt to challenging conditions. These crops have a comparative advantage in marginal lands where they withstand stress conditions and contribute to sustainable production. They also contribute to the diversity-richness and production stability of agro-ecosystems. Millets include sorghum, pearl millet, finger millet, foxtail millet, proso millet, barnyard millet, little millet and kodo millet while the other group which are not cereals but consumed as cereals and generally referred as pseudo-cereals comprises of grain amaranths, buckwheat and chenopods. Millets and Pseudo Cereals presents current information on the genetic architecture of important economic traits and the genomic resources for gene enabled breeding. This compilation contains information on the global status, available germplasm resources, nutritional value, breeding advancements, genomics applications and sustainability of agriculture through millets and pseudo-cereals cultivation. This book is a valuable resource for those conducting research and exploring new areas for advancing crop genetic understanding.

  • Advances in Clinical Chemistry

    • 1 Edición
    • Volumen 99
    • Gregory S. Makowski
    • Inglés
    Advances in Clinical Chemistry, Volume 99, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. The serial discusses the latest and most up-to-date technologies related to the field of clinical chemistry, with this release including chapters on Extracellular vesicle associated proteins as potential biomarkers, Molecular and non-molecular approaches to etiologic diagnosis of gastroenteritis, Circular RNAs and cancer: Opportunities and challenges, Mass spectrometry-based metabolomics for an in-depth questioning of human health, Application of microfluidic technology in cancer research and therapy, Advances in aptasensor technology, and much more.

  • Prions and Neurodegenerative Diseases

    • 1 Edición
    • Volumen 175
    • Inglés
    Prions and Neurodegenerative Diseases, Volume 172, in the Progress in Molecular Biology and Translational Science series, provides the most topical, informative and exciting monographs available on a wide variety of research topics. The series includes in-depth knowledge on the molecular biological aspects of organismal physiology, with this release including chapters on Cell-free amplification of prions: where do we stand? Transgenic mouse models for the study of prion diseases and much more.

  • ATP Synthase in Photosynthetic Organisms

    • 1 Edición
    • Volumen 96
    • Inglés
    Advances in Botanical Research, Volume 96, highlights new advances in the field, with this new volume presenting interesting chapters on the Structure and supramolecular architecture of chloroplast ATP synthase, Chloroplast ATP Synthase from Green Microalgae, Subunit movements in H-ATPases from chloroplasts detected by single molecule FRET, Regulation and control of the chloroplast ATP synthase: mechanisms and impact on maintaining efficient photosynthesis and photoprotection, Regulation machineries of ATP synthase from phototroph, How do we understand the formation of delta-pH in photosynthesis?, Regulation of photosynthesis by cyclic electron transport around photosystem, and the Biogenesis regulation of chloroplast ATP synthase.

  • Insect Pheromone Biochemistry and Molecular Biology

    • 2 Edición
    • Gary Blomquist + 1 más
    • Inglés
    Insect Pheromone Biochemistry and Molecular Biology, Second Edition, provides an updated and comprehensive review of the biochemistry and molecular biology of insect pheromone biosynthesis and reception. The book ties together historical information with recent discoveries, provides the reader with the current state of the field, and suggests where future research is headed. Written by international experts, many of whom pioneered studies on insect pheromone production and reception, this release updates the 2003 first edition with an emphasis on recent advances in the field. This book will be an important resource for entomologists and molecular biologists studying all areas of insect communication.

  • Gastronomy and Food Science

    • 1 Edición
    • Charis M. Galanakis
    • Inglés
    Gastronomy and Food Science fills the transfer knowledge gap between academia and industry by covering the interrelation of gastronomy and food and culinary science in one integral reference. Coverage of the holistic cuisine, culinary textures with food ingredients, the application of new technologies and gastronomy in shaping a healthy diet, and the recycling of culinary by-products using new is also covered in this important reference. Written for food scientists and technologists, food chemists, and nutritionists, researchers, academics, and professionals working in culinary science, culinary professionals and other food industry personnel, this book is sure to be a welcomed reference.

  • Advanced Food Analysis Tools

    Biosensors and Nanotechnology
    • 1 Edición
    • Rovina Kobun
    • Inglés
    Advanced Food Analysis Tools: Biosensors and Nanotechnology provides the latest information on innovative biosensors and tools that are used to perform on-site detection tests. Food safety is a global health goal, with the food industry providing testing and guidance to keep the population safe. Food contamination is mainly caused by harmful substances and biological organisms, including bacteria, viruses and parasites, which can all have a major impact on human health. The lack of specific, low-cost, rapid, sensitive and easy detection of harmful compounds has resulted in the development of the electrochemical technologies that are presented in this book.

  • Advances in Agronomy

    • 1 Edición
    • Volumen 164
    • Donald L. Sparks
    • Inglés
    Advances in Agronomy, Volume 164, the latest release in this leading reference on agronomy, contains a variety of updates and highlights new advances in the field. Each chapter is written by an international board of authors.

  • Enzymes – Mechanisms, Dynamics and Inhibition

    • 1 Edición
    • Volumen 122
    • Inglés
    Enzymes – Mechanisms, Dynamics and Inhibition, Volume 122, the latest release in the Advances in Protein Chemistry and Structural Biology series, highlights new advances in the field, with this new volume presenting new and interesting chapters on the topics. Each chapter is written by an international board of authors.

  • The Human Microbiome in Early Life

    Implications to Health and Disease
    • 1 Edición
    • Omry Koren + 1 más
    • Inglés
    The Human Microbiome in Early Life: Implications to Health and Disease presents recent research advances that have highlighted the significance of early life, possibly beginning before birth, in the establishment of both the microbiome and its role in health and disease. The book reviews current knowledge on the origins of the human microbiota in early life, presents exposures which may disturb normal microbial colonization, and covers their implications to the risk of disease. Finally, emerging means to modify the early human microbiome to improve health are discussed.

  • Fisheries and Aquaculture

    The Food Security of the Future
    • 1 Edición
    • Ágúst Einarsson + 1 más
    • Inglés
    Fisheries and Aquaculture: The Food Security of the Future takes a multidisciplinary approach in evaluating the fisheries and aquaculture sectors from the scientific and practical perspectives of industry professionals. The authors recognize the importance of looking at the industry from a value chain viewpoint, not only for food security but also for a blue economy. The book takes a unique and innovative approach to show how fisheries and aquaculture can achieve sustainability and how small fishery communities can become highly successful fishery and aquaculture communities and contribute to overall industry globalization. This is a practical and useful reference for a wide-ranging audience. It is for those who wish to make systematic efforts to develop their fisheries or aquaculture sectors, scientists and researchers, anyone in fisheries management or marine resource management, fish farmers, policy makers, leaders and regulators, operations researchers, as well as faculty and students.

  • Advances in Applied Microbiology

    • 1 Edición
    • Volumen 113
    • Geoffrey M. Gadd + 1 más
    • Inglés
    Advances in Applied Microbiology, Volume 113, continues the comprehensive reach of this widely read and authoritative review source in microbiology. Users will find invaluable references and information on a variety of areas relating to the topic, with this release focusing on Gaps in the Assortment of Rapid Assays for Microorganisms of Interest to the Dairy Industry, Metal reduction and corrosion by bacterial biofilms, The microbiology of red brines, Clostridium thermocellum: a microbial platform for high-value chemical production from lignocellulose, and The zincophore system in pathogenic yeasts.

  • Ketamine for Treatment-Resistant Depression

    Neurobiology and Applications
    • 1 Edición
    • Gustavo H. Vazquez + 2 más
    • Inglés
    Ketamine for Treatment-Resistant Depression: Neurobiology and Applications provides a simple, evidence-based overview for neuropsychiatrists and translational researchers on this medication, its mechanisms of actions, eligibility of patients for treatment, and the preparation and implementation of ketamine clinics.

  • Decision-Making in Adult Neurology

    • 1 Edición
    • Brett L. Cucchiara + 1 más
    • Inglés
    Written by neurologists for neurologists, Decision-Making in Adult Neurology provides practical guidance when encountering patients whose clinical presentation is unfamiliar or complex, or whose treatment path is not completely certain. This useful handbook is filled with diagnostic and treatment algorithms that encourage you to think systematically and follow a logical sequence through the steps necessary for efficient and effective decision-making.

  • Computational Modeling in Biomedical Engineering and Medical Physics

    • 1 Edición
    • Alexandru Morega + 2 más
    • Inglés
    Mathematical and numerical modelling of engineering problems in medicine is aimed at unveiling and understanding multidisciplinary interactions and processes and providing insights useful to clinical care and technology advances for better medical equipment and systems. When modelling medical problems, the engineer is confronted with multidisciplinary problems of electromagnetism, heat and mass transfer, and structural mechanics with, possibly, different time and space scales, which may raise concerns in formulating consistent, solvable mathematical models. Computational Medical Engineering presents a number of engineering for medicine problems that may be encountered in medical physics, procedures, diagnosis and monitoring techniques, including electrical activity of the heart, hemodynamic activity monitoring, magnetic drug targeting, bioheat models and thermography, RF and microwave hyperthermia, ablation, EMF dosimetry, and bioimpedance methods. The authors discuss the core approach methodology to pose and solve different problems of medical engineering, including essentials of mathematical modelling (e.g., criteria for well-posed problems); physics scaling (homogenization techniques); Constructal Law criteria in morphing shape and structure of systems with internal flows; computational domain construction (CAD and, or reconstruction techniques based on medical images); numerical modelling issues, and validation techniques used to ascertain numerical simulation results. In addition, new ideas and venues to investigate and understand finer scale models and merge them into continuous media medical physics are provided as case studies.

  • Enzyme Engineering and Evolution: Specific Enzyme Applications

    • 1 Edición
    • Volumen 644
    • Inglés
    Methods in Enzymology, Volume 644, the latest release in this ongoing serial, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Chapters in this new release include Site-directed recombination (SDR) in vivo: a fast and reliable tool to unveil beneficial epistasis, Creation and application of amine oxidase with expanded substrate specificities from porcine kidney D-amino acid oxidase, Methods to assess correlation networks for engineering transketolase, Exploration of Enzyme Diversity by Integrating Bioinformatics with Microfluidics, Engineering lytic polysaccharide monooxygenases (LPMOs), Emulsion-based directed evolution of enzymes in yeast, and much more.

  • Diabetología

    • 3 Edición
    • Louis Monnier + 1 más
    • Español
    La obra insiste en los aspectos prácticos del abordaje y en los nuevos métodos de exploración, se­guimiento y tratamiento. Las estrategias diagnósticas y terapéuticas novedosas se han desarrollado siguiendo los avances científicos más recientes. Se han incluido cinco capítulos nuevos, sobre los efectos de los tratamientos an­tihiperglucemiant... en las complicaciones cardiovasculares y renales del paciente diabético de tipo 2; la monitorización glucémica continua en las diabetes de tipos 1 y 2; la disbiosis intestinal y las enfermedades metabólicas; las complicaciones he­páticas, y Ramadán y diabetes. Asimismo, se ha profundizado en las nuevas recomendaciones diagnósticas y te­rapéuticas. A ellas se les han dedicado dos capítulos totalmente actualizados: «Ár­boles terapéuticos y de decisión en la diabetes de tipo 2» e «Insulinoterapia en la diabetes de tipos 1 y 2». Práctica y didáctica, esta obra está dirigida al conjunto de los profesionales sanita­rios que tienen que tratar con pacientes diabéticos.

  • Microbial and Natural Macromolecules

    Synthesis and Applications
    • 1 Edición
    • Surajit Das + 1 más
    • Inglés
    Microbial and Natural Macromolecules: Synthesis and Applications brings together active scientists and academicians in the field who share updated information and research outcomes from global experts. Microbial macromolecular diversity, molecular composure, genetics, usability of advanced molecular tools and techniques for their study as well as their applicability are discussed with detailed research perspectives.

  • Microbial Biotechnology in Food and Health

    • 1 Edición
    • Ramesh C. Ray
    • Inglés
    Microbial Biotechnology in Food and Health Science, volume one in the Applied Biotechnology Reviews series, offers two unique sections within the theme of genomics and bioprocessing and the bioengineering of microorganisms in the role of food science and human health. This volume provides review articles as the basis supporting biotechnological research useful to a wide scope of research initiatives. Important relevant information on genomics, proteomics and metabolomics are included as well as the emerging interdisciplinary area of synthetic biology which enables the metabolic engineering of microorganisms to produce pharmaceuticals. Applied Biotechnology Reviews is a series aimed at bringing all aspects of biotechnology as it is applied to food science – from agriculture through product processing into focus through topical volumes. Each volume will cover a relevant application approach in industrial biotechnology.

  • Epigenetics and Reproductive Health

    • 1 Edición
    • Volumen 21
    • Inglés
    Epigenetics and Reproductive Health, a new volume in the Translational Epigenetics series, provides a thorough overview and discussion of epigenetics in reproduction and implications for reproductive medicine. Twenty international researchers discuss epigenetic mechanisms operating during the formation of male and female gametes, fertilization and subsequent embryo and placental development, particularly in mammals and transgenerational epigenetic inheritance. This volume also addresses aberrant epigenetic changes influencing male and female infertility, pregnancy related disorders, and those potentially linked to therapeutic manipulations and assisted reproductive technologies. Emphasis is placed on identifying biomarkers for early detection of aberrant epigenetic mechanisms. Later chapters examine the possibility of correcting these epigenetic dysfunctions, as well as current challenges and next steps in research, enabling new translational discoveries and efforts towards developing therapeutics.

  • Microbial Pesticides

    Biological Resources, Production and Application
    • 1 Edición
    • Vladimir V. Gouli + 2 más
    • Inglés
    Microbial Pesticides: Biological Resources, Production and Application provides a concise and accessible introduction on the history of microbial pesticides, their impact on global ecology, human society and economies, as well as a thorough and tangible description of the state-of-the-art technologies available for the production, application, limitations and long–term viability of these bio-products. Information is listed per biological group (i.e., virus, bacteria, fungi, protozoa, microsporidia and microbial metabolites), and is supported by sound scientific data. The book is copiously illustrated, with original pictures clarifying the most common techniques and protocols utilized in microbiological biocontrol technology. Finally, images of all biological active ingredients currently used in commercially produced formulations, as well as laboratory developed formulations, are illustrated and listed in detailed tables for prompt access.

  • Integrative Pancreatic Intervention Therapy

    A Holistic Approach
    • 1 Edición
    • Maoquan Li + 4 más
    • Inglés
    Integrative Pancreatic Intervention Therapy: A Holistic Approach summarizes, in a systematic manner, the diagnosis and treatment of late, critical pancreatic diseases. The book gives insights into each interventional technique, with an ultimate goal of improving survival rates for late stage pancreatic cancer patients. Six sections cover basic and transformation research on pancreatic diseases, interventional therapy for benign pancreatic disease, interventional therapy for malignant pancreatic diseases, interventional therapy for pancreative cancer-related lesions, stem cell and targeted molecular therapy for pancreative carcinoma, and combined interventional therapy for pancreative carcinoma. This book will be useful for those looking to understand how best to apply interventional therapy for the improvement of late state pancreatic cancer treatment.

  • Theory and Applications of Nonparenteral Nanomedicines

    • 1 Edición
    • Prashant Kesharwani + 2 más
    • Inglés
    Theory and Applications of Nonparenteral Nanomedicines presents thoroughly analysed data and results regarding the potential of nanomedicines conceived by diverse non-parenteral routes. In the context of nanotechnology-based approaches, various routes such as oral, pulmonary, transdermal, delivery and local administration of nanomedicine have been utilized for the delivery of nanomedicine. This book discusses the non-parenteral application of nanomedicine, its regulatory implications, application of mucus penetrating nanocarrier, and detailed chapters on development of nanomedicines developed for drug delivery by various route. Beginning with a brief introduction to the non-parenteral delivery of nanomedicine and the safety and regulatory implications of the nanoformulations, further chapters discuss the physiology of the biological barriers, the specificity of the nanocarriers as well as their multiple applications. Theory and Applications of Nonparenteral Nanomedicines helps clinical researchers, researchers working in pharmaceutical industries, graduate students, and anyone working in the development of non-parenteral nanomedicines to understand the recent progress in the design and development of nanoformulations compatible with non-parenteral applications.

  • The Bowhead Whale

    Balaena Mysticetus: Biology and Human Interactions
    • 1 Edición
    • J.C. George + 1 más
    • Inglés
    The Bowhead Whale: Balaena mysticetus: Biology and Human Interactions covers bowhead biology from their anatomy and behavior, to conservation, distribution, ecology and evolution. The book also discusses the biological and physical aspects of the Arctic ecosystem in which these whales live, with careful attention paid to the dramatic changes taking place. A special section of the book describes the interactions of humans with bowheads in past and present, focusing on their importance to Indigenous communities and the challenges regarding entanglement in fishing gear, industrial noise and ship strikes. This volume brings together the knowledge of bowheads in one place for easy reference for scientists that study the species, marine mammal biologists, but, equally important, for everyone who is interested in the Arctic.

  • Human Milk Biochemistry and Infant Formula Manufacturing Technology

    • 2 Edición
    • Mingruo Guo
    • Inglés
    Human Milk Biochemistry and Infant Formula Manufacturing Technology, Second Edition covers the history of bottle feeding, its advantages and disadvantages when compared with breast-feeding, human milk biochemistry, trends and new developments in infant formula formulation and manufacturing, and best practices in infant formula processing technology and quality control. The book also covers human milk proteomics as a new, separate chapter and provides additional information on infant formula clinical trial guidelines. In addition, the book includes information about the formulation and processing of premature and low birth weight infant formula. This book is sure to be a welcome resource for professionals in the food and infant formula industry, academics and graduate students in fields like nutrition, food sciences, or nursing, nutritionists and health professionals, government officials working in relevant departments, and finally, anyone interested in human milk and infant formula.

  • Nature-Inspired Optimization Algorithms

    • 2 Edición
    • Xin-She Yang
    • Inglés
    Nature-Inspired Optimization Algorithms, Second Edition provides an introduction to all major nature-inspired algorithms for optimization. The book's unified approach, balancing algorithm introduction, theoretical background and practical implementation, complements extensive literature with case studies to illustrate how these algorithms work. Topics include particle swarm optimization, ant and bee algorithms, simulated annealing, cuckoo search, firefly algorithm, bat algorithm, flower algorithm, harmony search, algorithm analysis, constraint handling, hybrid methods, parameter tuning and control, and multi-objective optimization. This book can serve as an introductory book for graduates, for lecturers in computer science, engineering and natural sciences, and as a source of inspiration for new applications.

  • Introduction to the Constraints-Led Approach

    Application in Football
    • 1 Edición
    • Ben Bell
    • Inglés
    Introduction to the Constraints-Led Approach: Application in Football is a coaching resource football coaches can use to understand key theoretical components of the constraints-led approach. Sections discuss ecological dynamics, perception-action, degrees of freedom and complexity theory. Examples are provided within theoretical chapters to assist readers in their practical application. Over 30 designed practices using the constraints-led approach show readers how the theory translates into practice. These are ordered by the aim of the practice, from in possession, to defensive transition, to out of possession and attacking transition. Currently, there are no books on the market covering the constraints-led approach specific to football. The aim is to make this book accessible to football coaches without the necessity to focus solely on academic theory.

  • Digital Innovations in Healthcare Education and Training

    • 1 Edición
    • Stathis Th Konstantinidis + 2 más
    • Inglés
    Digital Innovations in Healthcare Education and Training discusses and debates the contemporary knowledge on the evolution of digital education, learning and the web and its integration and role within modern healthcare education and training. The book encompasses topics such as healthcare and medical education theories and methodologies, social learning as a formal and informal digital innovation, and the role of semantics in digital education. In addition, it examines how simulation, serious games, and virtual patients change learnings in healthcare, and how learning analytics and big data in healthcare education leads to personalized learning. Online pedagogy principles and applications, participatory educational design and educational technology as health intervention are bridged together to complement this collaborative effort. This book is a valuable resource for a broad audience, both technical and non-technical, including healthcare and medical tutors, health professionals, clinicians, web scientists, engineers, computer scientists and any other relevant professional interested in using and creating digital innovations for healthcare education and training.

  • Case Studies in the Beer Sector

    • 1 Edición
    • Roberta Capitello + 1 más
    • Inglés
    Case Studies in the Beer Sector investigates managerial and marketing dynamics in the beer sector. It explores the relevance of consumer science and its use as a tool for marketing strategies, putting special focus on small craft breweries. The book provides a variety of case studies from several countries to outline the global context within which the beer industry is developing. Real-life examples on how innovation and differentiation strategies affect consumer perceptions of beer are included, along with the relationship among breweries throughout the supply chain. Sections cover business strategy, sustainability, and how breweries are meeting the increasing demand for sustainable production processes. While this book provides a thorough reference for scholars and practitioners who work in the beer sector, it is also ideal for those studying business, agriculture, food engineering, technology, applied marketing and business strategy.

  • The Senses: A Comprehensive Reference

    • 2 Edición
    • Bernd Fritzsch
    • Inglés
    The Senses: A Comprehensive Reference, Second Edition, Seven Volume Set is a comprehensive reference work covering the range of topics that constitute current knowledge of the neural mechanisms underlying the different senses. This important work provides the most up-to-date, cutting-edge, comprehensive reference combining volumes on all major sensory modalities in one set. Offering 264 chapters from a distinguished team of international experts, The Senses lays out current knowledge on the anatomy, physiology, and molecular biology of sensory organs, in a collection of comprehensive chapters spanning 4 volumes. Topics covered include the perception, psychophysics, and higher order processing of sensory information, as well as disorders and new diagnostic and treatment methods. Written for a wide audience, this reference work provides students, scholars, medical doctors, as well as anyone interested in neuroscience, a comprehensive overview of the knowledge accumulated on the function of sense organs, sensory systems, and how the brain processes sensory input. As with the first edition, contributions from leading scholars from around the world will ensure The Senses offers a truly international portrait of sensory physiology. The set is the definitive reference on sensory neuroscience and provides the ultimate entry point into the review and original literature in Sensory Neuroscience enabling students and scientists to delve into the subject and deepen their knowledge.

  • Molecular Aspects of Neurodegeneration, Neuroprotection, and Regeneration in Neurological Disorders

    • 1 Edición
    • Akhlaq A. Farooqui
    • Inglés
    Molecular Aspects of Neurodegeneration, Neuroprotection, and Regeneration in Neurological Disorders presents readers with comprehensive and cutting-edge information on the neurochemical mechanisms of various types of neurological disorders. The book covers information on signal transduction processes associated with neurochemistry of neurological disorders, including neurodegenerative, neurotraumatic, and neuropsychiatric disorders. The book also discusses risk factors, symptoms, pathogenesis, biomarkers, and the potential treatments of neurological disorders. The comprehensive information in this monograph may not only help in early detection of various neurological disorders, but will also promote the discovery of new drugs.

  • Probiotic and Prebiotics in Foods: Challenges, Innovations and Advances

    • 1 Edición
    • Volumen 94
    • Inglés
    The Advances in Food and Nutrition Research series highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • pH-Interfering Agents as Chemosensitizers in Cancer Therapy

    • 1 Edición
    • Volumen 10
    • Claudiu T. Supuran + 1 más
    • Inglés
    pH Interfering Agents as Chemosensitizers In Cancer Therapy, Volume Thirteen, provides a detailed overview of the chemosensitizers for the treatment of cancer spanning from biochemical and structural features to pharmacology and drug-design, including technological applications. The book is structured with innovative outlines and a distinction between experimental and clinical results. The continuous discovery and assessment of the role played by old/new synthetic drugs, natural compounds and technological applications has led to the urgent need of classification in terms of biological activity, mechanism of action, clinical outcomes, cancer cell lines sensible to the treatment, and potentialities to better orient research in this field. Moreover, all the aspects relevant for medicinal chemistry (drug design, structure-activity relationships, permeability data, cytotoxicity, appropriate statistical procedures, and molecular modeling studies) are strictly considered.

  • Enzyme Engineering and Evolution: General Methods

    • 1 Edición
    • Volumen 643
    • Inglés
    This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field.

  • Update on Emerging Treatments for Migraine

    • 1 Edición
    • Volumen 255
    • Inglés
    Update on Emerging Treatments for Migraine, Volume 255, the latest release in the Progress in Brain Research series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • In Situ Molecular Pathology and Co-expression Analyses

    • 2 Edición
    • Gerard J. Nuovo
    • Inglés
    Major advancements in the field of in situ molecular pathology have occurred since publication of the first edition. In Situ Molecular Pathology and Co-expression Analyses, Second Edition, continues to teach both the molecular basis for the improvements and the actual protocols. This is the unique feature that separates it from the pack of other "cook-book" type approaches. The fields of in situ hybridization and immunohistochemistry have expanded rapidly where computer-based analyses systems have greatly expanded the power of these methods. Further, knowledge of the marked improvements in the reagents themselves since the first edition can make the difference of excellent versus misleading data. The automated platforms require that researchers and diagnostic biomedical investigators have a good understanding of the basics of in situ based tests, protocols, and biochemistry for troubleshooting in order to maximize the use of these platforms. This second edition focuses attention on straightforward protocols used to simultaneously detect two or more proteins/nucleic acids within intact tissue by doing co-expression analyses. Practicing molecular pathologists, diagnostic pathologists, laboratory directors, and toxicologists, as well as clinicians and researchers in training, will benefit from this clear presentation of protocols and theoretical framework. Data derived from in situ hybridization and immunohistochemistry...

  • Artificial Intelligence in Medicine

    Technical Basis and Clinical Applications
    • 1 Edición
    • Lei Xing + 2 más
    • Inglés
    Artificial Intelligence Medicine: Technical Basis and Clinical Applications presents a comprehensive overview of the field, ranging from its history and technical foundations, to specific clinical applications and finally to prospects. Artificial Intelligence (AI) is expanding across all domains at a breakneck speed. Medicine, with the availability of large multidimensional datasets, lends itself to strong potential advancement with the appropriate harnessing of AI. The integration of AI can occur throughout the continuum of medicine: from basic laboratory discovery to clinical application and healthcare delivery. Integrating AI within medicine has been met with both excitement and scepticism. By understanding how AI works, and developing an appreciation for both limitations and strengths, clinicians can harness its computational power to streamline workflow and improve patient care. It also provides the opportunity to improve upon research methodologies beyond what is currently available using traditional statistical approaches. On the other hand, computers scientists and data analysts can provide solutions, but often lack easy access to clinical insight that may help focus their efforts. This book provides vital background knowledge to help bring these two groups together, and to engage in more streamlined dialogue to yield productive collaborative solutions in the field of medicine.

  • Nano Drug Delivery Strategies for the Treatment of Cancers

    • 1 Edición
    • Awesh K. Yadav + 2 más
    • Inglés
    Nano Drug Delivery Strategies for the Treatment of Cancers discusses several current and promising approaches for the diagnosis and treatment of cancer by using the most recent developments in nanomedical technologies. The book presents introductory information about the biology of different types of cancer in order to provide the reader with knowledge on their specificities. In addition, it discusses various novel drug delivery systems, detailing their functionalities, expected outcomes and future developments in the field, focusing on brain, mouth and throat, breast, lung, liver, pancreas, stomach, colon, bool, skin and prostate cancers. The book is a valuable source for cancer researchers, oncologists, pharmacologists and nanotechnologists who are interested in novel drug delivery systems and devices for treatment of various types of cancer that take advantage of recent advances in this exciting field.

  • Plant Cell Biology

    • 1 Edición
    • Volumen 160
    • Inglés
    Plant Cell Biology, volume 160 in "Methods in Cell Biology", includes chapters on modern experimental procedures and applications developed for research in the broad area of plant cell biology. Topics covered in this volume include techniques for imaging and analyzing membrane dynamics and movement across membranes; cell wall composition, structure and mechanics; cytoskeleton dynamics and organization; cell development; ion channel physiology; cell mechanics; and methods related to quantifying cell morphogenesis.

  • Microbiomes and Plant Health

    Panoply and Their Applications
    • 1 Edición
    • Manoj Kumar Solanki + 3 más
    • Inglés
    Microbiomes and Plant Health: Panoply and Their Applications includes the most recent advances in phytobiome research. The book emphasizes the use of modern molecular tools such as smart delivery systems for microbiol inoculation, next-generation sequencing, and genome mapping. Chapters discuss a variety of applications and examples, including the sugarcane microbiome, rhizoengineering, nutrient recycling, sustainable agricultural practices and bio-potential of herbal medicinal plants. Written by a range of experts with real-world practical insights, this title is sure to be an essential read for plant and soil microbiologists, phytopathologists, agronomists, and researchers interested in sustainable forestry and agriculture practices.

  • Quadruplex Nucleic Acids As Targets For Medicinal Chemistry

    • 1 Edición
    • Volumen 54
    • Inglés
    The realisation that human, animal, viral and bacterial genomes all contain over-representation of higher-order quadruplex structures in regulatory and other pharmacologically-us... regions, has led to a large number of studies aimed at exploiting this findings for therapeutic and diagnostic purposes. Quadruplex-binding small molecules are starting to be evaluated in human clinical trials.

  • New Perspectives on Early Social-Cognitive Development

    • 1 Edición
    • Volumen 254
    • Inglés
    New Perspectives on Early Social-Cognitive Development, Volume 258 in the Progress in Brain Research series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Dynamics of Coordinated Attention, Investigating the Role of Neural Body Maps in Early Social-Cognitive Development: New Insights from Infant MEG and EEG, Motion tracking in developmental research: Methodological considerations and social-cognitive developmental applications, Early maturation of the social brain: How brain development provides a platform for the acquisition of social-cognitive competence, Getting a grip on early intention understanding: The role of motor, cognitive, and social factors, and much more.

  • Actin Cytoskeleton in Cancer Progression and Metastasis - Part A

    • 1 Edición
    • Volumen 355
    • Inglés
    Actin Cytoskeleton in Cancer Progression and Metastasis - Part A, Volume 355 in the International Review of Cell and Molecular Biology series, provides an overview of the roles of the actin cytoskeleton and some of its key structural regulators, including WASp, Paxillin, Myosin, Testin, L-Plastin and profilin, in central processes underlying cancer progression and metastasis, such as changes in cell morphology and gene expression, acquisition of migratory and invasive capabilities, and evasion from the immune response.

  • Metabolic and Bioenergetic Drivers of Neurodegenerative Disease: Treating Neurodegenerative Diseases as Metabolic Diseases

    • 1 Edición
    • Volumen 155
    • Inglés
    Metabolic Drivers and Bioenergetic Components of Neurodegenerative Disease reviews how the different aspects of metabolic dysfunction and consequent pathology associated with neurodegenerative diseases, including Alzheimer’s and Parkinson’s, can be targeted by novel treatment approaches. Topics covered include Cellular Senescence in Aging and Age-Related Disorders: Implications for Neurodegenerative Diseases; Repurposing GLP1 agonists for Neurodegenerative Diseases; Ketotherapeutics for Neurodegenerative Diseases; Enhancing Mitophagy as a Therapeutic Approach for Neurodegenerative Diseases; Harnessing Neurogenesis in the Adult Brain – A Role in Type 2 Diabetes Mellitus and Alzheimer’s disease; and much more.

  • Self-assessment Q&A in Clinical Laboratory Science, III

    • 1 Edición
    • Alan H.B. Wu
    • Inglés
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  • Systems Medicine

    Integrative, Qualitative and Computational Approaches
    • 1 Edición
    • Olaf Wolkenhauer
    • Inglés
    Technological advances in generated molecular and cell biological data are transforming biomedical research. Sequencing, multi-omics and imaging technologies are likely to have deep impact on the future of medical practice. In parallel to technological developments, methodologies to gather, integrate, visualize and analyze heterogeneous and large-scale data sets are needed to develop new approaches for diagnosis, prognosis and therapy. Systems Medicine: Integrative, Qualitative and Computational Approaches is an innovative, interdisciplinary and integrative approach that extends the concept of systems biology and the unprecedented insights that computational methods and mathematical modeling offer of the interactions and network behavior of complex biological systems, to novel clinically relevant applications for the design of more successful prognostic, diagnostic and therapeutic approaches. This 3 volume work features 132 entries from renowned experts in the fields and covers the tools, methods, algorithms and data analysis workflows used for integrating and analyzing multi-dimensional data routinely generated in clinical settings with the aim of providing medical practitioners with robust clinical decision support systems. Importantly the work delves into the applications of systems medicine in areas such as tumor systems biology, metabolic and cardiovascular diseases as well as immunology and infectious diseases amongst others. This is a fundamental resource for biomedical students and researchers as well as medical practitioners who need to need to adopt advances in computational tools and methods into the clinical practice.

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    • 1 Edición
    • Volumen 4
    • Susie Nilsson
    • Inglés
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    • 1 Edición
    • Susanne Doppler + 1 más
    • Inglés
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