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Elsevier

Libros en Ciencias de la Vida

  • International Review of Cell and Molecular Biology

    • 1 Edición
    • Volumen 354
    • Inglés
    International Review of Cell and Molecular Biology, Volume 354 reviews and details current advances in cell and molecular biology. The IRCMB series has a worldwide readership, maintaining a high standard by publishing invited articles on important and timely topics that are authored by prominent cell and molecular biologists. Sections in this new release include P73 in health and disease, The biology of LONP1, Molecular mechanisms of selective autophagy in Drosophila, Metabolic reprogramming and cisplatin resistance, The biology of polycystin 2, Pharmacological methods to transcriptionally modulate double-strand break DNA repair, Evolutionary insights into the aphid genome, Stratifying nutritional interventions in cancer therapy: next stop, personalized medicine, Vascular calcifications in health and disease

  • The Microbiome in Health and Disease

    • 1 Edición
    • Volumen 171
    • Inglés
    The Microbiome in Health and Disease, Volume 171 in the Progress in Molecular Biology and Translational Science series, provides the most topical, informative and exciting monographs available on a wide variety of research topics. The series includes in-depth knowledge on the molecular biological aspects of organismal physiology, with this release including chapters on Microbiome in health and disease, CNS development and microbiome in infants, A gut feeling in ALS, Microbiome (Virome) and virus infection, Bugs and Drugs: microbiome in medicine metabolism, Immunity, T cells, and microbiome, Salmonella (Bacterial) infection and cancer: of mice and men, and many other highly researched topics.

  • Evolutionary Neuroscience

    • 2 Edición
    • Jon H. Kaas
    • Inglés
    Evolutionary Neuroscience, Second Edition, is a collection of chapters on brain evolution that combines selected topics from the recent comprehensive reference, Evolution of Nervous Systems (Elsevier, Academic Press, 2017, 9780128040423). The selected chapters cover a broad range of topics, from historical theory, to the most recent deductions from comparative studies of brains. The articles are organized in sections focused on history, concepts and theory, the evolution of brains from early vertebrates to present-day fishes, amphibians, reptiles and birds, the evolution of mammalian brains, and the evolution of primate brains, including human brains. Each chapter is written by a leader or leaders in the field. Specific topics include brain character reconstruction, principles of brain scaling, basic features of vertebrate brains, the evolution of the major sensory systems, other parts of brains, what we can learn from fossils, the origin of neocortex, and the evolution of specializations of human brains. The collection of articles will be interesting to anyone who is curious about how brains evolved from the simpler nervous systems of the first vertebrates into the many different complex forms now found in present-day vertebrates.

  • Reproductive Technologies in Animals

    • 1 Edición
    • Giorgio Presicce
    • Inglés
    Reproductive Technologies in Animals provides the most updated and comprehensive knowledge on the various aspects and applications of reproductive technologies in production animals as well as companion, wild, exotic, and laboratory animals and birds. The text synthesizes historical information and recent discoveries, while dealing with economical and geographical issues related to the implementation of the same technologies. It also presents the effects of reproductive technology implementation on animal welfare and the possible threat of pathogen transmission.Reprodu... Technologies in Animals is an important resource for academics, researchers, professionals in public and private animal business, and students at the undergraduate and graduate levels, as it gives a full and detailed first-hand analysis of all species subjected to the use of reproductive technologies.

  • Music and the Aging Brain

    • 1 Edición
    • Lola Cuddy + 2 más
    • Inglés
    Music and the Aging Brain describes brain functioning in aging and addresses the power of music to protect the brain from loss of function and how to cope with the ravages of brain diseases that accompany aging. By studying the power of music in aging through the lens of neuroscience, behavioral, and clinical science, the book explains brain organization and function. Written for those researching the brain and aging, the book provides solid examples of research fundamentals, including rigorous standards for sample selection, control groups, description of intervention activities, measures of health outcomes, statistical methods, and logically stated conclusions.

  • Strategies for Curative Fluorescence-Guided Surgery of Cancer

    • 1 Edición
    • Robert Hoffman + 1 más
    • Inglés
    Strategies for Curative Fluorescence-Guided Surgery of Cancer is the first book to discuss how fluorescence-guided surgery can be successfully used during surgeries with several tumor types. FGS is one of the most exciting emerging modalities of surgery, especially cancer surgery, as it potentially allows the surgeon to visualize the actual margin of the tumor, thus greatly increasing the possibility of curative resection. The book discusses the applicability of FGS for several types of cancer, such as pancreatic cancer, liver metastasis, soft-tissue sarcoma, glioma, melanoma, and breast and lung cancer. This book is a valuable resource for cancer surgeons, cancer researchers and members of several other areas in the biomedical field who are interested in understanding this powerful technique.

  • Mechanisms Underlying Microbial Symbiosis

    • 1 Edición
    • Volumen 58
    • Inglés
    Insects engage in intimate associations with microbial symbionts that colonize their digestive systems or internal cells and tissues. The stability and near ubiquity of many of these "symbioses" implies their importance, a prediction supported through experimentation. With the advancing power of experimental methodologies and the growing accessibility of genomic techniques, insect science has reached a powerful new stage enabling the study of previously recalcitrant symbioses, including several with medical and agricultural significance. In this volume we publish a collection of chapters focused on the physiology of insect-microbe symbioses, emphasizing their mechanistic underpinnings, and the ecological and evolutionary causes and consequences of these interactions. Resident microbes modulate insect digestion, nutrition, detoxification, reproduction, interspecies signaling, and host-parasite interactions, and these chapters synthesize impactful, state-of-the art research on insect-microbe symbioses. Through discussions of the mechanisms that both stabilize and regulate these symbioses, these chapters yield further insight into the physiological integration between many insects and their influential microbial partners.

  • Drug Resistance in Colorectal Cancer: Molecular Mechanisms and Therapeutic Strategies

    • 1 Edición
    • Volumen 8
    • Chi Hin Cho + 1 más
    • Inglés
    Drug Resistance in Colorectal Cancer: Molecular Mechanisms and Therapeutic Strategies, Volume Eight, summarizes the molecular mechanisms of drug resistance in colorectal cancer, along with the most up-to-date therapeutic strategies available. The book discusses reasons why colorectal tumors become refractory during the progression of the disease, but also explains how drug resistance occurs during chemotherapy. In addition, users will find the current therapeutic strategies used by clinicians in their practice in treating colorectal cancer. The combination of conventional anticancer drugs with chemotherapy-sensiti... agents plays a pivotal role in improving the outcome of colorectal cancer patients, in particular those with drug-resistant cancer cells. From a clinical point-of-view, the content of this book provides clinicians with updated therapeutic strategies for a better choice of drugs for drug-resistant colorectal cancer patients. It will be a valuable source for cancer researchers, oncologists and several members of biomedical field who are dedicated to better treat patients with colorectal cancer.

  • Neurodevelopmental Disorders

    Comprehensive Developmental Neuroscience
    • 1 Edición
    • Bin Chen + 3 más
    • Inglés
    Neurodevelopmental Disorders, the latest release in the Comprehensive Developmental Neuroscience series, presents the most thorough coverage available, addressing all aspects on how the nervous system and its components develop. This book brings together the latest research in this rapidly evolving field, with section editors discussing the technological advances that are enabling the pursuit of new research on brain development. This volume focuses on neurodevelopmental disorders in humans and experimental organisms. Particular attention is paid to the effects of abnormal development and on new psychiatric/neurolog... treatments being developed based on our increased understanding of developmental mechanisms.

  • Aging

    Oxidative Stress and Dietary Antioxidants
    • 2 Edición
    • Victor R. Preedy + 1 más
    • Inglés
    Aging: Oxidative Stress and Dietary Antioxidants, Second Edition, bridges the trans-disciplinary divide and covers the science of oxidative stress in aging and the therapeutic use of natural antioxidants in the food matrix in a single volume. The second edition covers new trials and investigations used to determine the comprehensive properties of antioxidants, food items and extracts, as well as any adverse properties they may have. It has been updated to include new clinical human trials and a new section dedicated to animal models of aging. Throughtout the book the processes within the science of oxidative stress are described in concert with other processes, such as apoptosis, cell signaling, and receptor mediated responses. This approach recognizes that diseases are often multifactorial, and oxidative stress is a single component of this. Gerontologists, geriatricians, nutritionists, and dieticians are separated by divergent skills and professional disciplines that need to be bridged to advance preventative as well as treatment strategies. While gerontologists and geriatricians may study the underlying processes of aging, they are less likely to be conversant in the science of nutrition and dietetics. On the other hand, nutritionists and dietitians are less conversant with the detailed clinical background and science of gerontology. This book addresses this gap and brings each of these disciplines to bear on the processes inherent in the oxidative stress of aging. This will aid in better research, treatment and outcome for patients.

  • Sharks in Mexico: Research and Conservation Part B

    • 1 Edición
    • Volumen 85
    • Shawn Larson + 1 más
    • Inglés
    Sharks in Mexico: Research and Conservation, Volume 85 in the Advances in Marine Biology series, provides in-depth and up-to-date reviews on all aspects of marine biology that will appeal to postgraduates and researchers in marine biology, fisheries science, ecology, zoology and biological oceanography.

  • The Developing Microbiome

    Lessons from Early Life
    • 1 Edición
    • Erika Chiong Claud
    • Inglés
    The Developing Microbiome: Lessons from Early Life focuses on the establishment of the microbiome in early life, exposing it as a key mediator of diseases and health throughout the lifecycle. The content presents a comprehensive view of the status of the field and draws real-world correlations to health and disease states. It collates the significant research being done in the pediatric microbiome research space and bridges the knowledge gap showing the factors that impact health and disease states throughout the lifecycle. Finally, it offers knowledge on how the microbiome is and can be manipulated to promote change. This is a perfect reference for both researchers and clinical scientists who are interested in the role of the infant microbiome in health and disease, as well as gastroenterologists and pediatricians looking to affect change in their patients.

  • Stiehm's Immune Deficiencies

    Inborn Errors of Immunity
    • 2 Edición
    • Kathleen E. Sullivan + 1 más
    • Inglés
    Stiehm’s Immune Deficiencies: Inborn Errors in Immunity, Second Edition, is ideal for physicians and other caregivers who specialize in immunology, allergies, infectious diseases and pulmonary medicine. It provides a validated source of information for care delivery to patients, covering approaches to diagnosis that use both new genetic information and emphasize screening strategies. Management has changed dramatically over the past five years, so approaches to infection and autoimmunity are emphasized in an effort to improve outcomes and disseminate new information on the uses of targeted therapy.

  • Obesity, An Issue of Endocrinology and Metabolism Clinics of North America

    • 1 Edición
    • Volumen 49-2
    • Michael D. Jensen
    • Inglés
    This issue of Endocrinology and Metabolism Clinics will cover Obesity. Curated by Dr. Michael D. Jensen, this issue will explore topics in the field that are relevant for practicing clinicians. This issue is one of four selected each year by the series Consulting Editor, Adriana G. Ioachimescu. The volume will include articles on: The role of the environment in the “obesity epidemic,” Endoscopic treatments for obesity, Visceral fat, Role of commercial weight loss programs in medical management of obesity, Racial differences in metabolic consequences of fat gain, Sex differences in adipose tissue function, Common and rare complications of bariatric surgery, Strategies for physical activity interventions in the treatment of obesity, Effects of pregnancy on childhood overweight and obesity, Iatrogenic Obesity, Growth hormone and obesity, and Barriers and solutions for prescribing obesity pharmacotherapy.

  • Stress and Brain Health: In Clinical Conditions

    • 1 Edición
    • Volumen 152
    • Inglés
    Stress and Brain Health: In Clinical Conditions, Volume 152, examines up-to-date knowledge on how stress effects brain health. The book's wide-ranging topics include the effects of pre-natal and childhood stress on neurodevelopment and aging. Chapters cover Stress and neuropsychiatric disorders, Stress and schizophrenia, Stress and addictive behaviors, Stress and suicide, Stress as a factor in the progression of PD, Social prescribing for stress-related disorder, and more.

  • Gene Regulatory Networks

    • 1 Edición
    • Volumen 139
    • Inglés
    Gene Regulatory Networks, Volume 139 in the Current Topics in Developmental Biology series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Topics in this release include Mouse hindbrain GRN, Xenopus endoderm GRN – organogenesis, Vertebrate limb GRN, The notochord gene regulatory network in chordate evolution: conservation and divergence from Ciona to vertebrates, Ciona early embryo GRNs, Boolean logic models, Modeling GRN response to morphogen gradient, GRN architecture, Theory of GRN evolution, Evolution of fly segmentation GRNs, GRN evolution in echinoderms, Evolution of network specificity, and more.

  • An Evidence-Based Approach to the Management of Nasopharyngeal Cancer

    From Basic Science to Clinical Presentation and Treatment
    • 1 Edición
    • Baharudin Abdullah + 2 más
    • Inglés
    An Evidence-Based Approach to the Management of Nasopharyngeal Cancer: From Basic Science to Clinical Presentation and Treatment provides a comprehensive overview with updated management procedures for nasopharyngeal carcinoma. Written by experts on the subject, it is organized in a simple yet comprehensive manner to aid in the understanding of this complex condition. The book discusses several topics related to NPC, including epidemiology, pathophysiology, risk factors and treatment (surgical and non-surgical). Additionally, it discusses key features of clinical presentation of NPC, recent advances and promising new therapies. This will be a valuable source for clinicians, graduate students, oncologists and several members of the biomedical field who are interested in understanding nasopharyngeal cancer in a practical and applicable way.

  • Antibiotic Materials in Healthcare

    • 1 Edición
    • Varaprasad Kokkarachedu + 2 más
    • Inglés
    Antibiotic Materials in Healthcare provides significant information on antibiotic related issues, accurate solutions, and recent investigative information for health-related applications. In addition, the book addresses the design and development of antibiotics with advanced (physical, chemical and biological) properties, an analysis of materials, in vivo and in vitro applications, and their biomedical applications for healthcare.

  • Advances in Clinical Chemistry

    • 1 Edición
    • Volumen 97
    • Inglés
    Advances in Clinical Chemistry, Volume 97, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. The serial discusses the latest and most up-to-date technologies related to the field of clinical chemistry, with chapters in this new release covering metaproteomic analysis of human gut microbiome in digestive and metabolic diseases, liquid biopsy in ovarian cancer, advances in extracellular vesicles analysis, long non-coding RNA HOTAIR in cervical cancer: molecular marker, mechanistic insight, and therapeutic target, genomics of hypertriglyceridemia... cell free DNA biology and its involvement in breast carcinogenesis, and more.

  • Advances in Applied Microbiology

    • 1 Edición
    • Volumen 111
    • Geoffrey M. Gadd + 1 más
    • Inglés
    Advances in Applied Microbiology, Volume 111, continues the comprehensive reach of this widely read and authoritative review source in microbiology. Users will find invaluable references and information on a variety of areas relating to the topic.

  • Physiologically Based Pharmacokinetic (PBPK) Modeling

    Methods and Applications in Toxicology and Risk Assessment
    • 1 Edición
    • Jeffrey W. Fisher + 2 más
    • Inglés
    Physiologically Based Pharmacokinetic (PBPK) Modeling: Methods and Applications in Toxicology and Risk Assessment presents foundational principles, advanced techniques and applications of PBPK modeling. Contributions from experts in PBPK modeling cover topics such as pharmacokinetic principles, classical physiological models, the application of physiological models for dose-response and risk assessment, the use of in vitro information, and in silico methods. With end-of-chapter exercises that allow readers to practice and learn the skills associated with PBPK modeling, dose-response, and its applications to safety and risk assessments, this book is a foundational resource that provides practical coverage of PBPK modeling for graduate students, academics, researchers, and more.

  • Vibrational Spectroscopy in Protein Research

    From Purified Proteins to Aggregates and Assemblies
    • 1 Edición
    • Yukihiro Ozaki + 3 más
    • Inglés
    Vibrational Spectroscopy in Protein Research offers a thorough discussion of vibrational spectroscopy in protein research, providing researchers with clear, practical guidance on methods employed, areas of application, and modes of analysis. With chapter contributions from international leaders in the field, the book addresses basic principles of vibrational spectroscopy in protein research, instrumentation and technologies available, sampling methods, quantitative analysis, origin of group frequencies, and qualitative interpretation. In addition to discussing vibrational spectroscopy for the analysis of purified proteins, chapter authors also examine its use in studying complex protein systems, including protein aggregates, fibrous proteins, membrane proteins and protein assemblies. Emphasis throughout the book is placed on applications in human tissue, cell development, and disease analysis, with chapters dedicated to studies of molecular changes that occur during disease progression, as well as identifying changes in tissues and cells in disease studies.

  • The Plasticity of Sex

    The Molecular Biology and Clinical Features of Genomic Sex, Gender Identity and Sexual Behavior
    • 1 Edición
    • Marianne Legato J
    • Inglés
    The Plasticity of Sex: The Molecular Biology and Clinical Features of Genomic Sex, Gender Identity and Sexual Behavior provides a comprehensive view on the development of human sexuality. As there has been a crescendo of interest over the past several decades about the nature and diversity of human sexuality, this reference brings the evidence-based research into one place. The emergence of issues surrounding gender identity, genital ambivalence and the transition from one sex to another is striking, with the public and treating physicians alike clamoring for an evidence-based, comprehensive treatment of human sexuality and all its variations. This is a must-have reference for biomedical researchers in endocrinology, neuroscience, development biology, medical students, residents, and practicing physicians from all medical areas. Winner of the 2021 PROSE Award in Biomedicine from the Association of American Publishers!

  • The Code Stroke Handbook

    Approach to the Acute Stroke Patient
    • 1 Edición
    • Andrew Micieli + 4 más
    • Inglés
    A 65-year-old patient arrives at the Emergency Department with stroke symptoms that began 45 minutes ago. You are called STAT!Acute stroke management has changed dramatically in recent years. Tremendous advances have been made in acute treatments, diagnostic neuroimaging, and organized systems of care, and are enabling better outcomes for patients. Stroke has evolved from a largely untreatable condition in the acute phase to a true medical emergency that is potentially treatable—and sometimes curable. The Code Stroke emergency response refers to a coordinated team-based approach to stroke patient care that requires rapid and accurate assessment, diagnosis, and treatment in an effort to save the brain and minimize permanent damage.The Code Stroke Handbook contains the "essentials" of acute stroke to help clinicians provide best practice patient care. Designed to assist frontline physicians, nurses, paramedics, and medical learners at different levels of training, this book highlights clinical pearls and pitfalls, guideline recommendations, and other high-yield information not readily available in standard textbooks. It is filled with practical tips to prepare you for the next stroke emergency and reduce the anxiety you may feel when the Code Stroke pager rings.

  • Wheat and Barley Grain Biofortification

    • 1 Edición
    • Om Prakash Gupta + 5 más
    • Inglés
    Wheat and Barley Grain Biofortification addresses topics associated with the alleviation of malnutrition in globally diverse populations via wheat and barley biofortification. The book synthesizes the current trends of malnutrition across the globe, the need for wheat and barley nutritional enhancement and how agronomic, microbial and molecular understanding of biofortification can help in devising significant approaches and strategies. In addition, it includes discussions on potential genetic variability available and their efficient utilization in wheat and barley for molecular breeding for nutrients, challenges and opportunities for bioavailability, and technical advancement for analysis of bioavailability.

  • Long-Term Farming Systems Research

    Ensuring Food Security in Changing Scenarios
    • 1 Edición
    • Gurbir Bhullar + 1 más
    • Inglés
    Long-Term Farming Systems Research: Ensuring Food Security in Changing Scenarios presents the legacy and heritage of Long-Term Experiments (LTEs) in Agriculture while also addressing the challenges and potential solutions. The book discusses how LTEs form an important asset in understanding agriculture’s significant influence on life on earth. As global governments and development agencies try to achieve the Global Sustainable Development Goals (SDGs) of the United Nations, this book’s content is of unprecedented importance, providing insights into the interactions of agricultural production with ecological, economic and societal aspects. In this regard, this book offers a thorough resource of information based on experiences from various ongoing LTEs in different parts of the world. The contextual variety and geographic diversity presented in this book makes it useful for agricultural and environmental scientists, as well as students and educators in such fields. --- From the Editors: "Thanks to the excellent panel of our contributing authors, in this book, we have attempted to offer the widest possible thematic and geographical coverage on LTEs. Experts from different institutions leading LTEs across the globe have provided their perspectives on different aspects of LTEs, not only highlighting the unique knowledge contribution of LTEs, but also discussing the unique challenges of effectively managing LTEs and maintaining their relevance to changing scenarios. We hope that this book will offer something for everyone interested in the history, present and future of our agroecosystem."

  • Biotechnology Entrepreneurship

    Leading, Managing and Commercializing Innovative Technologies
    • 2 Edición
    • Craig Shimasaki
    • Inglés
    This second edition of Biotechnology Entrepreneurship: Leading, Managing, and Commercializing Innovative Technologies is an authoritative, easy-to-read guide covering biotechnology entrepreneurship and the process of commercializing innovative biotechnology products. This best practice resource is for professional training programs, individuals starting a biotech venture, and for managers and experienced practitioners leading biotech enterprises. It is a valuable resource for those working at any level in the biotech industry, and for professionals who support and provide essential resources and services to the biotech industry. This practical, “how-to” book is written by seasoned veterans experienced in each of the operational functions essential for starting, managing, and leading a successful biotech company.Biotechnolog... Entrepreneurship explains the biotech business components and underlying strategies, interspersed with practical lessons from successful biotech entrepreneurs, educators, and experienced practitioners. These veteran contributors share their insights on how to be successful in this challenging but exciting industry. Subjects range from technology licensing and translating an idea into a viable business, forming your legal company entity, securing angel and venture capital, navigating product development, FDA regulatory approval, and biomanufacturing.Thi... book is a user-friendly guide to decision-making and overall strategy written as a hands-on management tool for leaders and managers of these dynamic biotechnology ventures. If you are contemplating starting a biotech company, are a manager at any level, a seasoned veteran, or service provider in the biotech industry, this book is a “must read.”

  • Developmental and Fetal Origins of Differences in Monozygotic Twins

    From Genetics to Environmental Factors
    • 1 Edición
    • Alexandra Matias + 1 más
    • Inglés
    Developmental and Fetal Origins of Differences in Monozygotic Twins: From Genetics to Environmental Factors examines the major causes of discordance in monozygotic twins, from genetic, to environmental influences, including discussions on the genetic, epigenetic, fetal and environmental factors. Twin differences discussed include malformations, deformations and disruptions secondary to inequitable division of the early embryo, chromosome and single gene mosaicism, Nonrandom X chromosome inactivation, mitochondrial heteroplasmy, epigenetic variation, and variable and inequitable blood supply, among other influences. Differences in hemoglobin levels, placentation and amniotic fluid are also examined, while full color images illustrate discordant anomalies and twin differences throughout.

  • Histología y biología celular

    Introducción a la anatomía patológica
    • 5 Edición
    • Abraham L. Kierszenbaum + 1 más
    • Español
    Se trata del texto más innovador y aclamado en el contexto de la Histología, explicada desde el enfoque de la Biología Celular y la Anatomía Patológica. La obra presenta un abordaje básicamente visual de la disciplina, a todo color, el que página a página ofrece al estudiante un método de enseñanza integrada que conlleva una perfecta comprensión de los diferentes trastornos patológicos que se presentan en el cuerpo humano. La iconografía la convierte en una obra única en su campo, contabilizando más de 1.000 ilustraciones.Presen... nuevo contenido sobre la inmunoterapia antineoplásica, las células satélite y la reparación muscular, la vasculogénesis y la angiogénesis en relación con el tratamiento del cáncer, así como las terapias de reemplazo mitocondrial. A destacar que en esta edición el propio autor, el Dr. Kierszenbaum ha sido el revisor científico de la traducción al español. A través de E-book+(contenido en inglés), puede accederse aun conjunto de "mapas conceptuales animados" para cada uno de los capítulos, explicados paso a paso por el propio autor.

  • Advances in Agronomy

    • 1 Edición
    • Volumen 162
    • Inglés
    Advances in Agronomy, Volume 162, continues to be recognized as a leading reference and first-rate source for the latest research in agronomy. Each volume contains an eclectic group of reviews by leading scientists throughout the world. As always, the subjects covered are rich, varied and exemplary of the abundant subject matter addressed by this long-running serial.

  • Electrophysiology Measurements for Studying Neural Interfaces

    • 1 Edición
    • Mohammad M. Aria
    • Inglés
    Electrophysiology Measurements for Studying Neural Interfaces helps readers to choose a proper cell line and set-up for studying different bio-electronic interfaces before delving into the electrophysiology techniques available. Therefore, this book details the materials and devices needed for different types of neural stimulation such as photoelectrical and photothermal stimulations. Also, modern techniques like optical electrophysiology and calcium imaging in this book provides readers with more available approaches to monitor neural activities in addition to whole-cell patch-clamp technology.　

  • Methods in Cell Biology

    • 1 Edición
    • Volumen 158
    • Inglés
    Methods in Cell Biology, Volume 158, the latest release in this series, highlights new advances in the field, with this release covering How to orient cells in micro-cavities for high resolution imaging of cytokinesis and lumen formation, A body-on-a-chip (BOC) system for studying gut-liver interaction, Manipulating cultured mammalian cells for mitosis research, Live-cell FLIM-FRET using a commercially available system, A comparative analysis of methods to measure kinetochore-microtub... attachment stability, A workflow for visualizing human cancer biopsies using large-format electron microscopy, Isolation of stage-specific germ cells using facs in drosophila germarium, Computational analysis of filament polymerization dynamics in cytoskeletal networks, and more.

  • Drug Discovery Targeting Drug-Resistant Bacteria

    • 1 Edición
    • Prashant Kesharwani + 2 más
    • Inglés
    Drug Discovery Targeting Drug-Resistant Bacteria explores the status and possible future of developments in fighting drug-resistant bacteria. The book covers the majority of microbial diseases and the drugs targeting them. In addition, it discusses the potential targeting strategies and innovative approaches to address drug resistance. It brings together academic and industrial experts working on discovering and developing drugs targeting drug-resistant (DR) bacterial pathogens. New drugs active against drug-resistant pathogens are discussed, along with new strategies being used to discover molecules acting via new modes of action. In addition, alternative therapies such as peptides and phages are included. Pharmaceutical scientists, microbiologists, medical professionals, pathologists, researchers in the field of drug discovery, infectious diseases and microbial drug discovery both in academia and in industrial settings will find this book helpful.

  • An Industrial IoT Approach for Pharmaceutical Industry Growth

    Volume 2
    • 1 Edición
    • Valentina Emilia Balas + 2 más
    • Inglés
    An Industrial IoT Approach for Pharmaceutical Industry Growth, Volume Two uses an innovative approach to explore how the Internet of Things (IoT) and big data can improve approaches and make discoveries. Rapid growth of the IoT has encouraged many companies in the manufacturing sector to make use of this technology to unlock its potential. Using clear language and real-world case studies, this book discusses systems level from both a human-factors point-of-view and the perspective of networking, databases, privacy and anti-spoofing. The wide variety in topics presented offers multiple perspectives on how to integrate the Internet of Things into pharmaceutical manufacturing.This book represents a useful resource for researchers in pharmaceutical sciences, information and communication technologies, and those who specialize in healthcare and pharmacovigilance.

  • Atlas of Endoscopy Imaging in Inflammatory Bowel Disease

    • 1 Edición
    • Bo Shen
    • Inglés
    Atlas of Endoscopy Imaging in Inflammatory Bowel Disease is a complete reference providing all aspects of endoscopy imaging in inflammatory bowel disease (IBD). Building on the etiology and pathogenesis of IBD and taking into account the wide range of clinical presentations and phenotypes that reflect a long list of endoscopic features, this book systematically and exclusively presents all IBD-related endoscopy imaging for optimal understanding, diagnosis and management.

  • Chemical Tools for Imaging, Manipulating, and Tracking Biological Systems: Diverse Methods for Prokaryotic and Eukaryotic Systems

    • 1 Edición
    • Volumen 638
    • Inglés
    Chemical Tools for Imaging, Manipulating, and Tracking Biological Systems: Diverse Methods for Prokaryotic and Eukaryotic Systems, Volume 638, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Sample chapters from this new release include In vitro characterization of the colibactin-activatin... peptidase ClbP enables development of a fluorogenic activity probe, Using FDAA probes to study cell division in Bacillus subtilis, Chemoenzymatic synthesis of UDP-sugars, Chemical tools for selective activity profiling of bacterial penicillin-binding proteins, Chemical Probes Reveal and Extraseptal Mode of Cross-linking in Staphylococcus Aureus, and much more.

  • Applied Plant Virology

    Advances, Detection, and Antiviral Strategies
    • 1 Edición
    • L. P. Awasthi
    • Inglés
    Applied Plant Virology: Advances, Detection, and Antiviral Strategies provides an overview on recent developments and applications in the field of plant virology. The book begins with an introduction to important advances in plant virology, but then covers topics including techniques for assay detection and the diagnosis of plant viruses, the purification, isolation and characterization of plant viruses, the architecture of plant viruses, the replication of plant viruses, the physiology of virus-infected hosts, vectors of plant viruses, and the nomenclature and classification of plants. The book also discusses defense strategies by utilizing antiviral agents and management strategies of virus and viroid diseases. With contributions from an international collection of experts, this book presents a practical resource for plant virologists, plant pathologists, horticulturalists, agronomists, biotechnologists, academics and researchers interested in up-to-date technologies and information that advance the field of plant virology.

  • Information Resources in Toxicology, Volume 1: Background, Resources, and Tools

    • 5 Edición
    • Philip Wexler
    • Inglés
    This new fifth edition of Information Resources in Toxicology offers a consolidated entry portal for the study, research, and practice of toxicology. Both volumes represents a unique, wide-ranging, curated, international, annotated bibliography, and directory of major resources in toxicology and allied fields such as environmental and occupational health, chemical safety, and risk assessment. The editors and authors are among the leaders of the profession sharing their cumulative wisdom in toxicology’s subdisciplines. This edition keeps pace with the digital world in directing and linking readers to relevant websites and other online tools.Due to the increasing size of the hardcopy publication, the current edition has been divided into two volumes to make it easier to handle and consult. Volume 1: Background, Resources, and Tools, arranged in 5 parts, begins with chapters on the science of toxicology, its history, and informatics framework in Part 1. Part 2 continues with chapters organized by more specific subject such as cancer, clinical toxicology, genetic toxicology, etc. The categorization of chapters by resource format, for example, journals and newsletters, technical reports, organizations constitutes Part 3. Part 4 further considers toxicology’s presence via the Internet, databases, and software tools. Among the miscellaneous topics in the concluding Part 5 are laws and regulations, professional education, grants and funding, and patents. Volume 2: The Global Arena offers contributed chapters focusing on the toxicology contributions of over 40 countries, followed by a glossary of toxicological terms and an appendix of popular quotations related to the field.The book, offered in both print and electronic formats, is carefully structured, indexed, and cross-referenced to enable users to easily find answers to their questions or serendipitously locate useful knowledge they were not originally aware they needed. Among the many timely topics receiving increased emphasis are disaster preparedness, nanotechnology, -omics, risk assessment, societal implications such as ethics and the precautionary principle, climate change, and children’s environmental health.

  • Information Resources in Toxicology, Volume 2: The Global Arena

    • 5 Edición
    • Philip Wexler
    • Inglés
    This new fifth edition of Information Resources in Toxicology offers a consolidated entry portal for the study, research, and practice of toxicology. Both volumes represents a unique, wide-ranging, curated, international, annotated bibliography, and directory of major resources in toxicology and allied fields such as environmental and occupational health, chemical safety, and risk assessment. The editors and authors are among the leaders of the profession sharing their cumulative wisdom in toxicology’s subdisciplines. This edition keeps pace with the digital world in directing and linking readers to relevant websites and other online tools.Due to the increasing size of the hardcopy publication, the current edition has been divided into two volumes to make it easier to handle and consult. Volume 1: Background, Resources, and Tools, arranged in 5 parts, begins with chapters on the science of toxicology, its history, and informatics framework in Part 1. Part 2 continues with chapters organized by more specific subject such as cancer, clinical toxicology, genetic toxicology, etc. The categorization of chapters by resource format, for example, journals and newsletters, technical reports, organizations constitutes Part 3. Part 4 further considers toxicology’s presence via the Internet, databases, and software tools. Among the miscellaneous topics in the concluding Part 5 are laws and regulations, professional education, grants and funding, and patents. Volume 2: The Global Arena offers contributed chapters focusing on the toxicology contributions of over 40 countries, followed by a glossary of toxicological terms and an appendix of popular quotations related to the field.The book, offered in both print and electronic formats, is carefully structured, indexed, and cross-referenced to enable users to easily find answers to their questions or serendipitously locate useful knowledge they were not originally aware they needed. Among the many timely topics receiving increased emphasis are disaster preparedness, nanotechnology, -omics, risk assessment, societal implications such as ethics and the precautionary principle, climate change, and children’s environmental health.

  • Beneficial Microbes in Agro-Ecology

    Bacteria and Fungi
    • 1 Edición
    • N. Amaresan + 4 más
    • Inglés
    Beneficial Microbes in Agro-Ecology: Bacteria and Fungi is a complete resource on the agriculturally important beneficial microflora used in agricultural production technologies. Included are 30 different bacterial genera relevant in the sustainability, mechanisms, and beneficial natural processes that enhance soil fertility and plant growth. The second part of the book discusses 23 fungal genera used in agriculture for the management of plant diseases and plant growth promotion. Covering a wide range of bacteria and fungi on biocontrol and plant growth promoting properties, the book will help researchers, academics and advanced students in agro-ecology, plant microbiology, pathology, entomology, and nematology.

  • Peyronie's Disease: Pathophysiology and Treatment

    • 1 Edición
    • Giorgio Ivan Russo + 1 más
    • Inglés
    Peyronie's Disease: Pathophysiology and Treatment combines the basic research of Peyronie’s Disease with an overview of the clinical and practical management of the disease, providing the most comprehensive approach. Coverage includes etiology and psychological aspects of the disease, management according to European and US guidelines for both surgical and non-surgical treatments, and oral therapies and on-going research including stem cells. This book is perfect for urologists—particula... those who specialize in sexual medicine and/or infertility—and for Andrologists and Endocrinologists.

  • Medicinal and Aromatic Plants

    Expanding their Horizons through Omics
    • 1 Edición
    • Tariq Aftab + 1 más
    • Inglés
    Growing consumer interest in organic and herbal-based products has led to great demand in the botanicals industry in the past few years. However, the growing number of products utilizing medicinal and aromatic plants (MAPs) has threatened an estimated 9,000 medicinal plant species worldwide, making it critical to reevaluate their research and development, production, and utilization. Continuing advances in Omics methodologies and instrumentation are essential to understanding how plants cope with the dynamic nature of their growing environment, how yields and characteristics can be improved, and how to most effectively direct conservation efforts. With a focus on metabolomics, genomics, proteomics, transcriptomics, and more, Medicinal and Aromatic Plants: Expanding Their Horizons through Omics illustrates the genetic mechanisms of MAPs, providing a better understanding of MAPs conservation and methods to improve characteristics for medical applications. With an introduction on the role of MAPs in human health, subsequent chapters discuss using proteomics to increase MAP yields and plant quality, genome editing, and CRISPR/Cas9. A valuable resource for farmers, scientists, chemists, biochemists, pharmacists, and students interested in medicinal and aromatic plants and plant biology, Medicinal and Aromatic Plants: Expanding Their Horizons through Omics ensures readers have the background knowledge to put the necessary methodologies into practice themselves.

  • Molecular Advancements in Tropical Diseases Drug Discovery

    • 1 Edición
    • Gauri Misra + 1 más
    • Inglés
    Molecular Advancements in Tropical Diseases Drug Discovery presents in-depth knowledge relating to the detection of infection, epidemiology, drugs against various tropical diseases, new target sites for drug discovery and multidrug resistance issues using bioinformatics tools and approaches. The book's chapters are written by experts in their respective fields so that each disease is covered in a rational manner and with a solid foundation on existing facts and prospective research ideas.

  • Diabetes and Retinopathy

    • 1 Edición
    • Ayman S. El-Baz + 1 más
    • Inglés
    Diabetes and Retinopathy brings together the multifaceted information about the research and clinical application from academic, clinical, bioengineering and bioinformatics perspectives. The editors bring together a stellar cast of authors to pull together this diverse and interesting field. Academic researchers, bioengineers, new investigators and students interested in diabetes and retinopathy need an authoritative reference to bring this multidisciplinary field together to reduce the amount of time spent on source-searching and more time on actual research and the clinical application. This reference depicts the current clinical understanding of DR as well as the many scientific advances in understanding this condition.

  • Autophagy in Immune Response: Impact on Cancer Immunotherapy

    • 1 Edición
    • Volumen 1
    • Salem Chouaib
    • Inglés
    Autophagy in Immune Response: Impact on Cancer Immunotherapy focuses on the status and future directions of autophagy with respect to different aspects of its interaction with the immune system and immunotherapy. The book takes scientific research in autophagy a step further by presenting reputable information on the topic and offering integrated content with advancements in autophagy, from cell biology and biochemical research, to clinical treatments. This book is a valuable source for cancer researchers, oncologists, graduate students and several members of biomedical field who are interested in learning more on the relationship between autophagy and immunotherapies.

  • Biological Network Analysis

    Trends, Approaches, Graph Theory, and Algorithms
    • 1 Edición
    • Pietro Hiram Guzzi + 1 más
    • Inglés
    Biological Network Analysis: Trends, Approaches, Graph Theory, and Algorithms considers three major biological networks, including Gene Regulatory Networks (GRN), Protein-Protein Interaction Networks (PPIN), and Human Brain Connectomes. The book's authors discuss various graph theoretic and data analytics approaches used to analyze these networks with respect to available tools, technologies, standards, algorithms and databases for generating, representing and analyzing graphical data. As a wide variety of algorithms have been developed to analyze and compare networks, this book is a timely resource.

  • From Structure to Clinical Development: Allosteric Modulation of G Protein-Coupled Receptors

    • 1 Edición
    • Volumen 88
    • Inglés
    From Structure to Clinical Development: Allosteric Modulation of G Protein-Coupled Receptors, Volume 88, the latest release in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this updated edition include Targeting muscarinic M1 receptor in neurodegeneration, Photo‐switchable allosteric ligands, Computational approaches for the design of mGlu receptor allosteric modulators, Allosteric modulation of GLP‐1 receptor in metabolic disorders, Group II mGluR roles in the nervous system and their roles in addiction, RAMPs as allosteric modulators of Class B GPCRs, Structure‐based discovery and development of mGlu5 NAMs, and much more.

  • Ion Channels and Calcium Signaling in the Microcirculation

    • 1 Edición
    • Volumen 85
    • Inglés
    Ion Channels and Calcium Signaling in the Microcirculation, Volume 85, the latest release in the Current Topics in Membranes series, highlights the latest advances in the expression and function of ion channels and calcium signaling in vascular smooth muscle and endothelial cells in resistance arteries, arterioles and capillaries, critical components of microcirculation, the business end of the cardiovascular system. Leading experts have contributed chapters, including Smooth muscle ion channels and calcium signaling in the regulation of striated muscle arteriolar tone; Endothelial KIR channels as a key component of shear stress-induced mechanotransduction; Endothelial TRPV4 channels and vasodilator reactivity, and much more. Additional sections cover cerebral capillary endothelial TRPA channels and the regulation of blood flow; Endothelial mineralocorticoid receptors and the regulation of TRPV4 function in cerebral parenchymal arterioles in hypertension; Subcellular calcium signaling and myogenic tone development in the retinal microcirculation; Microvascular KIR channels: Basis, properties and regulation by lipid and hemodynamic forces, Ion channels and calcium signaling in capillary endothelial cells; Ion channels and calcium signaling in bladder arterioles and resistance arteries, and Myoendothelial feedback and endothelial IKCa and sKCa channels.

  • Nanoengineering in Musculoskeletal Regeneration

    • 1 Edición
    • Mehdi Razavi
    • Inglés
    Nanoengineering in Musculoskeletal Regeneration provides the reader an updated summary of the therapeutic pipeline—from biomedical discovery to clinical implementation—aimed at improving treatments for patients with conditions of the muscles, tendons, cartilage, meniscus, and bone. Regenerative medicine focuses on using stem cell biology to advance medical therapies for devastating disorders. This text presents novel, significant, and interdisciplinary theoretical and experimental results related to nanoscience and nanotechnology in musculoskeletal regeneration. Content includes basic, translational, and clinical research addressing musculoskeletal repair and regeneration for the treatment of diseases and injuries of the skeleton and its associated tissues.Musculoskele... degeneration and complications from injuries have become more prevalent as people live longer and increasingly participate in rigorous athletic and recreational activities. Additionally, defects in skeletal tissues may immobilize people and cause inflammation and pain. Musculoskeletal regeneration research provides solutions to repair, restore, or replace skeletal elements and associated tissues that are affected by acute injury, chronic degeneration, genetic dysfunction, and cancer-related defects. The goal of musculoskeletal regeneration medicine research is to improve quality of life and outcomes for people with musculoskeletal injury or degradation.

  • Aquaculture and By-Products: Challenges and Opportunities in the Use of Alternative Protein Sources and Bioactive Compounds

    • 1 Edición
    • Volumen 92
    • Inglés
    Aquaculture and By-products: Challenges and Opportunities, Volume 92 in the Advances in Food and Nutrition Research series, explores the potential use of aquaculture and by-products as sources of proteins and bioactive compounds. Alternative extraction techniques to obtain, isolate and purify proteins and bioactive from aquaculture and by-products are thoroughly discussed. Chapters in this new volume include Alternative extraction techniques to obtain, isolate and purify proteins and bioactive from aquaculture and by-products, Development of new food and pharmaceutical products: Nutraceuticals and food additives, Evaluation of the protein and bioactive compound bioaccessibility/bio... and citotoxicity of the extracts obtained from aquaculture and by-products, and more.

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