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Elsevier

Libros en Ciencias de la Vida

  • Chemical Tools for Imaging, Manipulating, and Tracking Biological Systems: Diverse Chemical, Optical and Bioorthogonal Methods

    • 1 Edición
    • Volumen 641
    • Inglés
    Chemical Tools for Imaging, Manipulating, and Tracking Biological Systems: Diverse Chemical, Optical and Bioorthogonal Methods, Volume 641 in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Chapters in this new release include caged cyclopropanes with improved tetrazine ligation kinetics, an analysis of metabolically labeled inositol phosphate messengers by NMR, cell-permeant caged inositol pyrophosphates for probing β-cells, imaging phospholipase D activity with clickable alcohols via transphosphatidylati... fluorescent biorthogonal labeling of class B GPCRs in live cells, near-infrared photoactivatable nitric oxide donors with integrated photoacoustic monitoring, and much more.

  • Our Wired Nerves

    The Human Nerve Connectome
    • 1 Edición
    • Douglas W Zochodne
    • Inglés
    The nervous system is a complex, sophisticated system that regulates and coordinates body activities. It is made up of two major divisions: the central nervous system consisting of the brain and spinal cord and the peripheral nervous system. This consists of all other neural elements, including the peripheral nerves and the autonomic nerves. Peripheral nerves are the essential connections between the brain and spinal cord and the body. Without nerves there is no movement or sensation. Our Wired Nerves: The Human Nerve Connectome, reviews the essential anatomy and physiology of the peripheral nerve. It introduces the reader to what neuropathies are, how pain arises from damaged nerves and how nerves might be regenerated, including new and exciting ideas over how to coax their regrowth. Written by Dr. Douglas Zochodne leading expert in the field, and first book to focus on the Peripheral nerves it will surely be an essential reference for researchers and clinicians alike.

  • Autism

    • 1 Edición
    • Volumen 173
    • Inglés
    Autism, Volume 173 in the Progress in Molecular Biology and Translational Science series, provides the most topical, informative and exciting monographs available on a wide variety of research topics. Chapters in this new release include updates on atypical brain development in autism spectrum disorder, predicting early diagnosis of autism spectrum disorder using neural and behavioral measures, the roles of the endocannabinoid system in autism spectrum disorder, the neurobiology of sensory processing in autism spectrum disorder, the effects of oxytocin administration on individuals with ASD, resting-state abnormalities of posterior cingulate in autism spectrum disorder, and more.

  • Mechanisms of Action in Disease and Recovery in Integrative Cardiovascular Chinese Medicine

    Volume 6
    • 1 Edición
    • Anika Niambi Al-Shura
    • Inglés
    Mechanisms of Action in Disease and Recovery in Integrative Cardiovascular Chinese Medicine, volume six in the Integrative Cardiovascular Chinese Medicine series, presents the structure, function and pathology of the cardiovascular system from Traditional Chinese and Western Medicine perspectives. Sections discuss cardiac acu-anatomy, including cardiac cells and heart structure, gastrointestinal cells and mouth, esophagus, stomach, small and large intestine structures, and more, while other chapters cover the qi, yin and yang roles in cardiac rhythm and pumping actions and the pathology of the heart and vascular system and the zang and fu relationship with other body organs. This important reference will aid cardiovascular researchers in the study of integrative Chinese and Western medicine with its clear, structured base that will guide clinical practice and encourage collaboration between Chinese and Western medicine practitioners.

  • Fighting the Opioid Epidemic

    The Role of Providers and the Clinical Laboratory in Understanding Who is Vulnerable
    • 1 Edición
    • Amitava Dasgupta
    • Inglés
    Fighting the Opioid Epidemic: The Role of Providers and the Clinical Laboratory in Understanding Who Is Vulnerable covers the important aspects that are essential in fighting the opioid epidemic. This succinct reference highlights how the toxicology laboratory can play a vital role in fighting the opioid epidemic by implementing a robust system for drugs of abuse testing as well as drug testing in pain management patients. It targets health care professionals in a technical manner, discussing polymorphisms of important genes that may be associated with increased vulnerability of alcohol and drug addiction to an individual.

  • Cold Pressed Oils

    Green Technology, Bioactive Compounds, Functionality, and Applications
    • 1 Edición
    • Mohamed Fawzy Ramadan
    • Inglés
    Cold Pressed Oils: Green Technology, Bioactive Compounds, Functionality, and Applications creates a multidisciplinary forum of discussion on recent advances in chemistry and the functionality of bioactive phytochemicals in lipids found in cold pressed oils. Chapters explore different cold pressed oil, focusing on cold press extraction and processing, composition, physicochemical characteristics, organoleptic attributes, nutritional quality, oxidative stability, food applications, and functional and health-promoting traits. Edited by a team of experts, the book brings a diversity of developments in food science to scientists, chemists, nutritionists, and students in nutrition, lipids chemistry and technology, agricultural science, pharmaceuticals, cosmetics, nutraceuticals and many other fields.

  • Advances in Food and Nutrition Research

    • 1 Edición
    • Volumen 93
    • Fidel Toldra
    • Inglés
    Advances in Food and Nutrition Research, Volume 93, provides information on nutrients in foods and how to avoid their deficiency, especially for those essential nutrients that should be present in the diet. Specific topics covered in this new release include drying, a relevant unit operation in the manufacture of foods and nutritional products, polycyclic aromatic hydrocarbons in edible oils and fatty foods, including occurrence, formation, analysis, change, and control, food allergens and their characterization, molecular properties and clinical implications, the design, quality, safety and efficacy of extensively hydrolyzed formula for the management of cow’s milk protein allergy, and much more. The series provides the latest advances on the identification and characterization of emerging bioactive compounds with putative health benefits, as well as up-to-date information on food science, including raw materials, production, processing, distribution and consumption.

  • Obesity Hypoventilation Syndrome

    From Physiologic Principles to Clinical Practice
    • 1 Edición
    • Aiman Tulaimat
    • Inglés
    Obesity Hypoventilation Syndrome: From Physiologic Principles to Clinical Practice summarizes the current state of knowledge regarding the epidemiology, physiology and treatment of obesity hypoventilation syndrome (OHS). Currently, the identification and management of OHS is suboptimal, especially in the acute setting, hence the misdiagnosis or mislabeling of the problem has a significant impact on patient outcomes. This volume brings together all aspects of assessment and management into a main resource for understanding the complex physiological and clinical consequences of this condition.

  • Sperling Pediatric Endocrinology

    • 5 Edición
    • Mark A. Sperling
    • Inglés
    An ideal resource for both pediatricians and endocrinologists, Sperling’s Pediatric Endocrinology, 5th Edition, brings you fully up to date with accelerating research; new discoveries in metabolic, biochemical and molecular mechanisms; and the resulting advances in today’s clinical care. The editorial team of world-renowned pediatric endocrinologists led by Dr. Mark Sperling, as well as expert contributing authors, cover comprehensive and current aspects of both basic science and clinical practice. Whether you’re preparing for certification or have extensive clinical experience, this detailed, authoritative reference helps you increase your knowledge and determine the best possible course for every patient.

  • Neural Regenerative Nanomedicine

    • 1 Edición
    • Mehdi Razavi
    • Inglés
    Neural Regenerative Nanomedicine presents novel, significant, experimental results relating to nanoscience and nanotechnology in neural regeneration. As current research is at the forefront of healing the nervous system, the content in the book focuses on basic, translational and clinical research in neural repair and regeneration. Chapters focus on stem cell biology to advance medical therapies for devastating disorders, the complex, delicate structures that make up the nervous system, and neurodegenerative diseases that cause progressive deterioration, including Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis (ALS), multiple sclerosis and multiple system atrophy.

  • Present Knowledge in Nutrition

    Basic Nutrition and Metabolism
    • 11 Edición
    • Bernadette P. Marriott + 3 más
    • Inglés
    Present Knowledge in Nutrition: Basic Nutrition and Metabolism, Eleventh Edition, provides an accessible, referenced source on the most current information in the broad field of nutrition. Now broken into two volumes and updated to reflect scientific advancements since the publication of the last edition, the book includes expanded coverage on basic nutrition, metabolism and clinical and applied topics. This volume provides coverage of macronutrients, vitamins, minerals and other dietary components and concludes with new approaches in nutrition science that apply to many, if not all, of the nutrients and dietary components presented throughout the reference. Advanced undergraduate, graduate and postgraduate students in nutrition, public health, medicine and related fields will find this resource useful. In addition, professionals in academia and medicine, including clinicians, dietitians, physicians, health professionals, academics and industrial and government researchers will find the content extremely useful. The book was produced in cooperation with the International Life Sciences Institute (https://ilsi.org/).

  • Present Knowledge in Nutrition

    Clinical and Applied Topics in Nutrition
    • 11 Edición
    • Bernadette P. Marriott + 3 más
    • Inglés
    Present Knowledge in Nutrition, Eleventh Edition, provides an accessible, highly readable, referenced, source of the most current, reliable, and comprehensive information in the broad field of nutrition. Now broken into two, separate volumes, and updated to reflect scientific advancements since the publication of its tenth edition, Present Knowledge in Nutrition, Eleventh Edition includes expanded coverage on the topics of basic nutrition and metabolism and clinical and applied topics in nutrition. This volume, Present Knowledge in Nutrition: Clinical and Applied Topics in Nutrition, addresses life stage nutrition and maintaining health, nutrition monitoring, measurement, and regulation, and important topics in clinical nutrition. Authored by an international group of subject-matter experts, with the guidance of four editors with complementary areas of expertise, Present Knowledge in Nutrition, Eleventh Edition will continue to be a go-to resource for advanced undergraduate, graduate and postgraduate students in nutrition, public health, medicine, and related fields; professionals in academia and medicine, including clinicians, dietitians, physicians, and other health professionals; and academic, industrial and government researchers, including those in nutrition and public health. The book was produced in cooperation with the International Life Sciences Institute (https://ilsi.org/).

  • Extrusion Cooking

    Cereal Grains Processing
    • 2 Edición
    • Girish M. Ganjyal
    • Inglés
    Extrusion Cooking provides a detailed description of extrusion processing with an in-depth exploration of cereal grains processing. In particular, the book addresses the basic principles of extrusion processing, various extruder parts and their design principles, food ingredients and their characteristics as they relate to extrusion. It also discusses physicochemical changes in the different ingredient components as they are processed in an extruder, modeling and control of extrusion process, scale-up aspects, extrusion plant design, food safety in extrusion, new advancements in extrusion, and a look into the future of extrusion. This valuable text serves as a one-volume reference on extrusion processing for food industry professionals and students.

  • Recent Advances in iPSC Disease Modeling

    • 1 Edición
    • Alexander Birbrair
    • Inglés
    Recent Advances in iPSC Disease Modeling, Volume One addresses how induced pluripotent stem cells can be used to model various diseases. This new volume teaches readers about current advances in the field, describing the use of induced pluripotent stem cells to model several diseases in vitro, and thus enabling us to study the cellular and molecular mechanisms involved in different pathologies. Further insights into these mechanisms will have important implications for our understanding of disease appearance, development and progression. The volume is written for researchers and scientists in stem cell therapy, cell biology, regenerative medicine and organ transplantation specialists. In recent years, remarkable progress has been made in the obtention of induced pluripotent stem cells and their differentiation into several cell types, tissues and organs using state-of-art techniques. Hence, these advantages have facilitated the identification of key targets and further defining on the molecular basis of several disorders.

  • Kidney Biomarkers

    Clinical Aspects and Laboratory Determination
    • 1 Edición
    • Seema S. Ahuja + 1 más
    • Inglés
    Since laboratory testing and biomarkers are an integral part in the diagnosis and treatment of kidney disease, Kidney Biomarkers: Clinical Aspects and Laboratory Determination covers currently used biomarkers as well as markers that are in development. Laboratories are increasingly more involved in the follow-up confirmatory laboratory testing and this unique volume showcases the collaboration needed to solve diagnostic clinical puzzles between the laboratory and clinician. This volume provides guidance on laboratory test selection and results interpretation in patients. Sources of inaccurate results in the measurement of kidney biomarkers are discussed along with possibility of eliminating such interferences. Each chapter is organized with a uniform easy-to-follow format with insightful case examples highlighting the collaboration between clinical laboratorians and clinicians.

  • A Comprehensive Overview of Irritable Bowel Syndrome

    Clinical and Basic Science Aspects
    • 1 Edición
    • Jakub Fichna
    • Inglés
    A Comprehensive Overview of Irritable Bowel Syndrome: Clinical and Basic Science Aspects presents up-to-date knowledge in the field and provides a comprehensive summary of this area of study, including an overview on IBS, starting from its pathogenesis, including genetic, microbial and physiological background, through symptom recognition, diagnosis and IBS treatment, both non-pharmacological and pharmacological.

  • Obesity

    Global Impact and Epidemiology
    • 1 Edición
    • Raman Mehrzad
    • Inglés
    Obesity continues to accelerate resulting in an unprecedented epidemic that shows no significant signs of slowing down any time soon. The World Health Organization reports that in 2016, nearly 2 billion adults were overweight and that worldwide obesity has nearly tripled since 1975. Obesity: Global Impact and Epidemiology is an important tool in proving a link to new knowledge, serving researchers and clinicians. The field of obesity is evolving very quickly and there is an abundance of scientific data that has emerged and is emerging constantly. Researchers and physicians need new updated information about the epidemiology and global impact of obesity that come from authors that have a wide perspective in the field. For health professionals and researchers, there is a need to understand how obesity begins. While a simple question, the answer is very complex.

  • Biodiversity and Biomedicine

    Our Future
    • 1 Edición
    • Munir Ozturk + 2 más
    • Inglés
    Biodiversity and Biomedicine: Our Future provides a new outlook on Earth’s animal, plant, and fungi species as vital sources for human health treatments. While there are over 10 million various species on the planet, only 2 million have been discovered and named. This book identifies modern ways to incorporate Earth’s species into biomedical practices and emphasizes the need for biodiversity conservation. Written by leading biodiversity and biomedical experts, the book begins with new insights on the benefits of biologically active compounds found in fungi and plants, including a chapter on the use of wild fruits as a treatment option. The book goes on to discuss the roles of animals, such as amphibians and reptiles, and how the threatened presence of these species must be reversed to conserve biodiversity. It also discusses marine organisms, including plants, animals, and microbes, as essential in contributing to human health. Biodiversity and Biomedicine: Our Future is a vital source for researchers and practitioners specializing in biodiversity and conservation studies. Students in natural medicine and biological conservation will also find this useful to learn of the world’s most bio-rich communities and the molecular diversity of various species.

  • Weed Science

    Cannabis Controversies and Challenges
    • 1 Edición
    • Godfrey Pearlson
    • Inglés
    WHAT DO WE KNOW ABOUT MARIJUANA AND HOW DO WE KNOW IT? Marijuana is the most frequently consumed illicit drug worldwide, with over 158.8 million users, according to the UN. Responding to public pressure, the US federal government is likely to legalize recreational marijuana within the next few years. With increasing numbers of people using cannabis both medically and recreationally there are many looming questions that only science can answer. These include: What's likely to happen, both good and bad, if the US legalizes marijuana? What are some simple, science-based rules to separate fact from fiction and to help guide policy in the highly contentious marijuana debate? Exactly what is cannabis doing in the brain that gets us high? A journey through THC neuroscience Does cannabis really have medical benefits - what's the evidence? To what extent does cannabis impair driving? Can smoking marijuana in adolescence affect IQ or risk for developing schizophrenia? Is marijuana safe to use during pregnancy?

  • Human Brainstem

    Cytoarchitecture, Chemoarchitecture, Myeloarchitecture
    • 1 Edición
    • George Paxinos + 2 más
    • Inglés
    Human Brainstem: Cytoarchitecture, Chemoarchitecture, Myeloarchitecture explores how the human brainstem has been impeded by the unavailability of an up-to-date, comprehensive, diagrammatic and photographic atlas. Now, with the first detailed atlas on the human brainstem in more than twenty years, this book presents an accurate, comprehensive and convenient reference for students, researchers and pathologists.

  • Systems and Synthetic Metabolic Engineering

    • 1 Edición
    • Yanfeng Liu + 2 más
    • Inglés
    Systems and Synthetic Metabolic Engineering provides an overview of the development of metabolic engineering within medicine that is fueled by systems and synthetic biology. These newly developed, successful strategies of metabolic engineering guide the audience on how to propose and test proper strategies for metabolic engineering research. In addition to introductory, regulatory and challenges in the field, the book also covers dynamic control and autonomous regulation to control cell metabolism, along with computational modeling and industrial applications. The book is written by leaders in the field, making it ideal for synthetic biologists, researchers, students and anyone working in this area.

  • Biomarkers for Traumatic Brain Injury

    • 1 Edición
    • Alan H.B. Wu + 1 más
    • Inglés
    Biomarkers for Traumatic Brain Injury provides a comprehensive overview on the selection and implementation of serum-based and saliva-based biomarkers for traumatic brain injury. The book presents an economic analysis for implementing TBI biomarkers into clinical practice. In addition, it discusses the analytical tools needed to implement TBI biomarkers, including specifications for testing instruments and interpretative software. Neurologists, emergency department physicians, intensivists, and clinical laboratorians will find this book a great resource from which to familiarize themselves with the issues and processes regarding TBI biomarkers. Approximately 2 million people in the U.S. sustain a traumatic brain injury (TBI) each year with over 250,000 hospitalizations and 50,000 deaths. There has been a significant rise in interest in diagnosing mild concussions, particularly in the sports world. While imaging has been the gold standard, these procedures are costly and not always available. There is great potential in using serum-based biomarkers, hence the book seeks to enlighten readers on new possibilities.

  • Sex and Cardiac Electrophysiology

    Differences in Cardiac Electrical Disorders Between Men and Women
    • 1 Edición
    • Marek Malik
    • Inglés
    Sex and Cardiac Electrophysiology: Differences in Cardiac Electrical Disorders Between Men and Women is a comprehensive investigation into all aspects of sex differences in cardiac electrophysiology. As there are substantial differences between female and male patients in physiology, pathology triggering factors, disease progression, clinical approaches and treatment outcome, this book provides a comprehensive examination. In cardiology, the differences between women and men are more recognized, hence this title summarizes these important differences, providing the essential information needed for clinical specialists and researchers involved in the design and implementation of clinical studies.

  • Biometals in Autism Spectrum Disorders

    • 1 Edición
    • Andreas Grabrucker
    • Inglés
    Biometals in Autism Spectrum Disorders focuses on trace metals and autism. Compared to other references examining ASDs or metallomics, this book presents findings of abnormal metal homeostasis in ASD, providing an overview of current findings on trace metal biology, its role in ASD etiology, and how abnormal trace metal biology may be a common factor of several genetic and non-genetic causes of ASDs that were once considered unrelated. This comprehensive resource opens new vistas for the development of new therapies based on the targeted manipulation of trace metal homeostasis that will generate new awareness surrounding trace metal levels during pregnancy.

  • Logic and Critical Thinking in the Biomedical Sciences

    Volume 2: Deductions Based Upon Quantitative Data
    • 1 Edición
    • Jules J. Berman
    • Inglés
    All too often, individuals engaged in the biomedical sciences assume that numeric data must be left to the proper authorities (e.g., statisticians and data analysts) who are trained to apply sophisticated mathematical algorithms to sets of data. This is a terrible mistake. Individuals with keen observational skills, regardless of their mathematical training, are in the best position to draw correct inferences from their own data and to guide the subsequent implementation of robust, mathematical analyses. Volume 2 of Logic and Critical Thinking in the Biomedical Sciences provides readers with a repertoire of deductive non-mathematical methods that will help them draw useful inferences from their own data.Volumes 1 and 2 of Logic and Critical Thinking in the Biomedical Sciences are written for biomedical scientists and college-level students engaged in any of the life sciences, including bioinformatics and related data sciences.

  • The Mediterranean Diet

    An Evidence-Based Approach
    • 2 Edición
    • Victor R. Preedy + 1 más
    • Inglés
    The Mediterranean Diet: An Evidence-Based Approach, Second Edition provides authoritative material on the many facets surrounding the complex interrelationships between diet, nutrition, health and well-being. The book discusses historical, cultural and scientific foundations, with chapters delving into nutritional adequacy, agricultural practices, food culture, mortality, quality of life, children and adolescents, behavior, cardiovascular diseases, diet quality, nutritional knowledge, nuts, minerals, olive oil, hydroxytyrosol, water, antioxidant nutritional status, ketogenics, adiposity, metabolic syndrome, type 2 diabetes, cardiovascular risk, nutrigenetics, epigenetics, the link between epigenetics and pregnancy, gene polymorphisms bone health, insulin signaling inflammatory gene expression, and more.

  • Visually Memorable Neuroanatomy for Beginners

    • 1 Edición
    • Min Suk Chung + 1 más
    • Inglés
    Visually Memorable Neuroanatomy for Beginners takes a close look at the anatomy of the human brain and teaches readers to identify and examine its structures in a relatable way. Unlike large textbooks that deliver a superficial overview of the subject, this book explores the anatomy and physiology of the brain using mnemonic techniques and informative comic figures that present brain regions at an introductory level, allowing readers to easily identify different parts of the brain. This volume is appropriate for undergraduate and graduate students, postdoctoral fellows, and researchers in the medicine, health sciences, and biological sciences. Beginning with the morphology of the brain and spinal cord, this book then explores the somatic nerve and autonomic nerve, the cranial nerve and spinal nerve, the function of the brain, and concludes with the development of the nervous system.

  • Statistics in Medicine

    • 4 Edición
    • Robert H. Riffenburgh + 1 más
    • Inglés
    Statistics in Medicine, Fourth Edition, helps medical and biomedical investigators design and answer questions about analyzing and interpreting data and predicting the sample size required to achieve useful results. It makes medical statistics easy for the non-biostatistician by outlining common methods used in 90% of medical research. The text covers how to plan studies from conception to publication, what to do with data, and follows with step-by-step instructions for biostatistical methods from the simplest levels, to more sophisticated methods now used in medical articles. Examples from almost every medical specialty, and from dentistry, nursing, pharmacy and health care management are provided. This book does not require background knowledge of statistics or mathematics beyond high school algebra and provides abundant clinical examples and exercises to reinforce concepts. It is a valuable source for biomedical researchers, healthcare providers and anyone who conducts research or quality improvement projects.

  • Logic and Critical Thinking in the Biomedical Sciences

    Volume I: Deductions Based Upon Simple Observations
    • 1 Edición
    • Jules J. Berman
    • Inglés
    Science is not a collection of facts. Science is the process by which we draw inferences from facts. Volume I of Logic and Critical Thinking in the Biomedical Sciences invites readers to linger over a collection of common observations to see what inferences can be drawn, when one applies a bit of deductive logic. If we just think about what we observe, it is often possible to discover profound biomedical insights.Volumes 1 and 2 of Logic and Critical Thinking in the Biomedical Sciences are written for biomedical scientists and college-level students engaged in any of the life sciences, including bioinformatics and related data sciences.

  • Epigenetics Methods

    • 1 Edición
    • Volumen 18
    • Trygve O. Tollefsbol
    • Inglés
    In recent years, the field of epigenetics has grown significantly, driving new understanding of human developmental processes and disease expression, as well as advances in diagnostics and therapeutics. As the field of epigenetics continues to grow, methods and technologies have multiplied, resulting in a wide range of approaches and tools researchers might employ. Epigenetics Methods offers comprehensive instruction in methods, protocols, and experimental approaches applied in field of epigenetics. Here, across thirty-five chapters, specialists offer step-by-step overviews of methods used to study various epigenetic mechanisms, as employed in basic and translational research. Leading the reader from fundamental to more advanced methods, the book begins with thorough instruction in DNA methylation techniques and gene or locus-specific methylation analyses, followed by histone modification methods, chromatin evaluation, enzyme analyses of histone methylation, and studies of non-coding RNAs as epigenetic modulators. Recently developed techniques and technologies discussed include single-cell epigenomics, epigenetic editing, computational epigenetics, systems biology epigenetic methods, and forensic epigenetic approaches. Epigenetics methods currently in-development, and their implication for future research, are also considered in-depth. In addition, as with the wider life sciences, reproducibility across experiments, labs, and subdisciplines is a growing issue for epigenetics researchers. This volume provides consensus-driven methods instruction and overviews. Tollefsbol and contributing authors survey the range of existing methods; identify best practices, common themes, and challenges; and bring unity of approach to a diverse and ever-evolving field.

  • State of the Art Evaluation of the Head and Neck, An Issue of Neuroimaging Clinics of North America

    • 1 Edición
    • Volumen 30-3
    • Ashok Srinivasan
    • Inglés
    This issue of Neuroimaging Clinics of North America focuses on State of the Art Evaluation of the Head and Neck and is edited by Dr. Ashok Srinivasan. Articles will include: Diffusion MR in the head and neck: Principles and applications; Perfusion imaging in the head and neck: Go with the flow; MR spectroscopy of the head and neck: Principles, applications and challenges; Technological improvements in head and neck MR: At the cutting edge; Dual Energy CT in head and neck imaging: Pushing the envelope; Role of Ultrasound in head and neck evaluation; PET imaging in the head and neck: Current state and future directions; Patient centric head and neck cancer radiation therapy: Role of advanced imaging; AI in head and neck imaging: Glimpse into the future; NIRADS: Principles and implementation; Common data elements in head and neck reporting; and more!

  • Novel Therapies in Head and Neck Cancer: Beyond the Horizon

    • 1 Edición
    • Volumen 9
    • Maie A. St. John + 1 más
    • Inglés
    Novel Therapies in Head and Neck Cancer: Beyond the Horizon, Volume Twelve, provides a high-level synthesis of the latest treatments and outcomes relating to head and neck cancer. Chemotherapy and immunotherapy for those cancer types are rapidly evolving, and an updated source based on the expertise of internationally renowned researchers is necessary. This book discusses the outcome of recent trials using chemotherapy, novel approaches for HPV+ SCCA, cases in which immunotherapy is more likely to be successful, and precision medicine based on target therapies. Additionally, new approaches for rare diseases in head and neck and novel drug delivery platforms are presented. This book will be a very useful source so that students, scientists and clinicians who can be facile with the data, build on what is known, and continue to offer cutting-edge, validated therapies to all patients.

  • Managing Health in the Genomic Era

    A Guide to Family Health History and Disease Risk
    • 1 Edición
    • Vincent Henrich + 2 más
    • Inglés
    In Managing Health in the Genomic Era: A Guide to Family Health History and Disease Risk, Drs. Vincent C. Henrich, Lori A. Orlando, and Brian H. Shirts discuss the practical considerations surrounding the use of genomic and genetic tests to manage patient health, to provide adult disease risk assessment, to improve diagnosis, and to support effective interventions and treatment. In 10 chapters, evidence-based information and case studies are described and examine the central place of family health history (FHH) in genomic medicine, tools and strategies for compiling and analyzing family health history, how to identify existing and novel genetic markers, how to identify lineage specific (or rare) variants within families, and how to find effective interventions based on genetic testing results and FHH. Factors that influence clinical practice, including gene-environment interactions, FHH social networking, direct to consumer (DTC) genetic testing and data sharing, algorithms for analyzing genetic data, and patient counseling are discussed from the standpoint of clinical practice. Here, frontline healthcare providers will discover succinct commentary and key examples to assist with their local needs. Relevant principles of genetic biology and inheritance are explored and guidance on available support networks and online resources is also provided.

  • Intelligence-Based Medicine

    Artificial Intelligence and Human Cognition in Clinical Medicine and Healthcare
    • 1 Edición
    • Anthony C. Chang
    • Inglés
    Intelligence-Based Medicine: Data Science, Artificial Intelligence, and Human Cognition in Clinical Medicine and Healthcare provides a multidisciplinary and comprehensive survey of artificial intelligence concepts and methodologies with real life applications in healthcare and medicine. Authored by a senior physician-data scientist, the book presents an intellectual and academic interface between the medical and the data science domains that is symmetric and balanced.The content consists of basic concepts of artificial intelligence and its real-life applications in a myriad of medical areas as well as medical and surgical subspecialties. It brings section summaries to emphasize key concepts delineated in each section; mini-topics authored by world-renowned experts in the respective key areas for their personal perspective; and a compendium of practical resources, such as glossary, references, best articles, and top companies.The goal of the book is to inspire clinicians to embrace the artificial intelligence methodologies as well as to educate data scientists about the medical ecosystem, in order to create a transformational paradigm for healthcare and medicine by using this emerging new technology.

  • Rapid Acting Antidepressants

    • 1 Edición
    • Volumen 89
    • Inglés
    The Advances in Pharmacology series presents a variety of chapters from the best authors in the field.

  • Reactive Oxygen Species (ROS), Nanoparticles, and Endoplasmic Reticulum (ER) Stress-Induced Cell Death Mechanisms

    • 1 Edición
    • Loutfy H. Madkour
    • Inglés
    Reactive Oxygen Species (ROS), Nanoparticles, and Endoplasmic Reticulum (ER) Stress-Induced Cell Death Mechanisms presents the role of ROS‒mediated pathways cellular signaling stress, endoplasmic reticulum (ER) stress, oxidative stress, oxidative damage, nanomaterials, and the mechanisms by which metalloids and nanoparticles induce their toxic effects. The book covers the ecotoxicology of environmental heavy metal ions and free radicals on macromolecules cells organisms, heavy metals‒induced cell responses, oxidative stress, the source of oxidants, and the roles of ROS, oxidative stress and oxidative damage mechanisms. It also examines the nanotoxicity, cytotoxicity and genotoxicity mechanisms of nanomaterials and the effects of nanoparticle interactions. Antioxidant defense therapy and strategies for treatment round out the book, making it an ideal resource for researchers and professional scientists in toxicology, environmental chemistry, environmental science, nanomaterials and the pharmaceutical sciences.

  • Advances in Marine Biology

    • 1 Edición
    • Volumen 86
    • Inglés
    Advances in Marine Biology, Volume 86, the latest release in a series that has been providing in-depth and up-to-date reviews on all aspects of marine biology since 1963, updates on many topics that will appeal to postgraduates and researchers in marine biology, fisheries science, ecology, zoology and biological oceanography. Chapters in this new release include Marine Environmental DNA: Approaches, Applications, and Opportunities, and The Biology and Ecology of the Banana Prawns.

  • Receptor Tyrosine Kinases

    • 1 Edición
    • Volumen 147
    • Inglés
    Receptor Tyrosine Kinases, Volume 147 in the Advances in Cancer Research series, provides invaluable information on the exciting and fast-moving field of cancer research in the area of Receptor Tyrosine Kinases (RTKs) in the context of major basic science and translational advances, their importance in the development of a large number of anti-cancer drugs over the decades, and a peek into postulated advances in the coming decades for a number of RTK. Chapters in this new release are contributed by a group of International leading scientists who have a rich history in this field.

  • Rosenberg's Molecular and Genetic Basis of Neurological and Psychiatric Disease

    Volume 1
    • 6 Edición
    • Roger N. Rosenberg + 1 más
    • Inglés
    Rosenberg’s Molecular and Genetic Basis of Neurologic and Psychiatric Disease, Sixth Edition: Volume One, provides a comprehensive introduction and reference to the foundations and key practical aspects relevant to neurologic and psychiatric disease. A favorite of over three generations of students, clinicians and scholars, this new edition retains and expands the informative, concise and critical tone of the first edition. This is an essential reference for general medical practitioners, neurologists, psychiatrists, geneticists, and related professionals, and for the neuroscience and neurology research community. The content covers all aspects essential to the practice of neurogenetics to inform clinical diagnosis, treatment and genetic counseling. Every chapter has been thoroughly revised or newly commissioned to reflect the latest scientific and medical advances by an international team of leading scientists and clinicians. The contents have been expanded to include disorders for which a genetic basis has been recently identified, together with abundant original illustrations that convey and clarify the key points of the text in an attractive, didactic format.

  • Meningiomas, Part II

    • 1 Edición
    • Volumen 170
    • Michael W. McDermott
    • Inglés
    Meningiomas, Volume 170, Part Two, discusses tumors that arise from the coverings of the brain and spinal cord. In this updated volume of the Handbook of Clinical Neurology, experts in the field - from basic scientists to skilled neurosurgeons, provide up-to-date synopses of each topic as it relates directly to this class of tumor. Surgical and radiation therapy, which remain the mainstays of treatment, are a major focus, but coverage also includes potential molecular avenues for the development of effective medical treatments. This book serves as a comprehensive review of the neurosurgical issues surrounding this extremely common brain tumor. Few procedures in surgery are more immediately formidable than an attack upon a large tumor of this type, hence the greatest challenge of treatment is the need to complete tumor removal without creating new neurologic deficit.

  • Maternal Effect Genes in Development

    • 1 Edición
    • Volumen 140
    • Inglés
    Current Topics in Developmental Biology series highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by one or more members of an international board of authors.

  • Rosenberg's Molecular and Genetic Basis of Neurological and Psychiatric Disease

    Volume 2
    • 6 Edición
    • Roger N. Rosenberg + 1 más
    • Inglés
    Rosenberg’s Molecular and Genetic Basis of Neurologic and Psychiatric Disease, Sixth Edition: Volume Two provides a comprehensive introduction and reference to the foundations and practical aspects relevant to the majority of neurologic and psychiatric disease. This updated volume focuses on degenerative disorders, movement disorders, neuro-oncology, neurocutaneous disorders, epilepsy, white matter diseases, neuropathies and neuronopathies, muscle and neuromuscular junction disorders, stroke, psychiatric disease, and a neurologic gene map. A favorite of over three generations of students, clinicians and scholars, this new edition retains and expands on the informative, concise and critical tone of the first edition. This is an essential reference for general medical practitioners, neurologists, psychiatrists, geneticists, related professionals, and for the neuroscience and neurology research community at large. The content covers all aspects essential to the practice of neurogenetics to inform clinical diagnosis, treatment and genetic counseling.

  • Toxicology Cases for the Clinical and Forensic Laboratory

    • 1 Edición
    • Hema Ketha + 1 más
    • Inglés
    Toxicology Cases for the Clinical and Forensic Laboratory brings together carefully selected case studies to teach important principles relating to drug and toxin exposures. Each case study includes contemporary clinical and forensic toxicologist studies that include a comprehensive analytical and clinical approach to patient management and address overdoses from designer drugs, to NSAIDS, to opioids, to stimulants. These cases present a comprehensive, analytical and clinical approach to managing a drug overdose. This is a must-have reference for clinical and forensic laboratory scientists, along with toxicology and pathology residents who need to know aspects of both.

  • Neuronal Chloride Transporters in Health and Disease

    • 1 Edición
    • Xin Tang
    • Inglés
    In the past several years, there has been an exciting body of new research that links impairments in the expression or function of neuronal chloride transporters to a growing number of diseases spanning from autism to brain aging. This book introduces the core concepts and highlights the recent advances in understanding the physiology and pathophysiology of the KCC and NKCC families of neuronal chloride transporters. Neuronal chloride transporter biology is reviewed, including roles in setting the transmembrane chloride gradient and the chloride transport-independen... functions, such as regulating excitatory neurotransmission. Chapters are also dedicated to addressing the structure, post-translational modification, membrane trafficking, and protein interaction partners of neuronal chloride transporters, as well as the genetic and environmental factors that regulate their expression in neurons and the novel therapeutic approaches that target neuronal chloride transporters to treat neurological diseases. This new volume will provide readers with an up-to-date summary of the recent advances in neuronal chloride transporter research, with particular emphasis on some of the key emerging topics in the field.

  • Human Pluripotent Stem Cell Derived Organoid Models

    • 1 Edición
    • Volumen 159
    • Inglés
    Human Pluripotent Stem Cell Derived Organoid Models, Volume 159 highlights recent and emerging advances that describe organoid differentiation protocols for the different organ systems that implement organoids as tools to understand complexity and maturation, high content drug screening, disease modeling, development and evolution. Specific chapters in this new release include Pluripotent stem cell derived gastric organoids, Pluripotent stem cell derived esophageal organoids, Pluripotent stem cell derived small intestinal organoids, Pluripotent stem cell derived colonic organoids, Pluripotent stem cell intestinal organoids with an Enteric Nervous System, Pluripotent stem cell derived airway organoids, Pluripotent stem cell derived alveolar organoids, and much more.

  • Wheat - An Exceptional Crop

    Botanical Features, Chemistry, Utilization, Nutritional and Health Aspects
    • 1 Edición
    • Herbert Wieser + 2 más
    • Inglés
    Wheat - An Exceptional Crop: Botanical Features, Chemistry, Utilization, Nutritional and Health Aspects presents the exceptional position of wheat among food crops. The book demonstrates the benefits and drawbacks of wheat from a wheat science, nutrition and technology perspective. Organized into 13 chapters, chapters 1 - 3 present a basic overview of wheat; chapters 4 - 6 explore the overall benefits of wheat for the general population, and chapters 7 - 13 assess wheat-related disorders that affect a small portion of the population. Wheat - An Exceptional Crop: Botanical Features, Chemistry, Utilization, Nutritional and Health Aspects is an exceptional reference for those working in and researching the fields of agronomy, food chemistry, food technology, nutrition, allergology and gastroenterology.

  • Transgenic Technology Based Value Addition in Plant Biotechnology

    • 1 Edición
    • Usha Kiran + 2 más
    • Inglés
    Transgenic Technology Based Value Addition in Plant Biotechnology discusses the principles, methodology and applications of transgenic technologies. With step-by-step methods on genome editing techniques and a range of potential applications, from improving crop yield to increasing therapeutic efficacy, this book is a one-stop reference for plant gene editing technologies. It will be of particular interest to researchers interested in plant biotechnology and plant genetics, as well as agricultural scientists and those concerned with medicinal plants.

  • Artificial Intelligence in Cancer

    Diagnostic to Tailored Treatment
    • 1 Edición
    • Smaranda Belciug
    • Inglés
    Artificial Intelligence in Cancer: Diagnostic to Tailored Treatment provides theoretical concepts and practical techniques of AI and its applications in cancer management, building a roadmap on how to use AI in cancer at different stages of healthcare. It discusses topics such as the impactful role of AI during diagnosis and how it can support clinicians to make better decisions, AI tools to help pathologists identify exact types of cancer, how AI supports tumor profiling and can assist surgeons, and the gains in precision for oncologists using AI tools. Additionally, it provides information on AI used for survival and remission/recurrence analysis. The book is a valuable source for bioinformaticians, cancer researchers, oncologists, clinicians and members of the biomedical field who want to understand the promising field of AI applications in cancer management.

  • Camptothecin and Camptothecin Producing Plants

    Botany, Chemistry, Anticancer Activity and Biotechnology
    • 1 Edición
    • T. Pullaiah + 4 más
    • Inglés
    Camptothecin and Camptothecin Producing Plants: Botany, Chemistry, Anticancer Activity and Biotechnology provides updated information on camptothecin yielding plants, chemical diversity of camptothecin, extraction and exploitation methods, biosynthesis, biotechnological production and enhancement for drug delivery, and the pharmacological properties of the drugs. The book focuses on camptothecin anticancer properties based on recent developments of biotechnology. Topics emphasize anticancer activities, biosynthesis, potent derivatives currently undergoing experimental phases, and biotechnological methods to enhance the production. This book is a valuable source for cancer researchers, oncologists, biotechnologists, pharmacologists and members of the biomedical field who are interested in camptothecin and its applicability in cancer treatment.

  • Autophagy in Health and Disease

    • 1 Edición
    • Volumen 172
    • Inglés
    Autophagy in Health and Disease, Volume 175, presents the latest insights from renowned experts in the field who discuss the key role of autophagic responses in the preservation of cellular and organismal homeostasis and how defects in the molecular apparatus for autophagy drive or accompany disease. Specific chapters in this new release include Crosstalk between autophagy and cell death signaling: mechanisms and therapeutic relevance, C. elegans to model autophagy-related human disorders, Autophagy in Kidney Disease: advances and therapeutic potential, Autophagy in Chronic Lung Disease, Autophagy in motoneuronal disorders, Strategies employed by viruses to manipulate autophagy, and much more.

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