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Elsevier

Libros en Neurociencia

  • Thermoregulation Part I

    From Basic Neuroscience to Clinical Neurology
    • 1 Edición
    • Volumen 156
    • Inglés
    Thermoregulation, Part I: From Basic Neuroscience to Clinical Neurology, Volume 154, not only reviews how body temperature regulation changes in neurological diseases, but also how this aspect affects the course and outcomes of each disease. Other sections of the volume review three therapeutic approaches that are aimed at manipulating body temperature, including induced hypothermia, induced hyperthermia and antipyretic therapy. The book is comprised of nine sections across two volumes, five dealing with the basic aspects of body temperature regulation and four dealing with the clinical aspects. Basic sections cover the Thermoregulation system, Thermoreceptors, Thermoeffectors, Neural pathways, and Thermoregulation as a homeostatic function. In addition, the book covers the physiology and neuroanatomy of the thermoregulation system and provides descriptions of how the regulation of body temperature intervenes with other physiological functions (such as sleep, osmoregulation, and immunity), stress, exercise and aging. Basic sections serve as an introduction to the four clinical sections: Body Temperature, Clinical Significance, Abnormal Body Temperature, Thermoregulation in Neurological Disease and Therapeutic Interventions.

  • Neurosurgical Neuropsychology

    The Practical Application of Neuropsychology in the Neurosurgical Practice
    • 1 Edición
    • Caleb M. Pearson + 2 más
    • Inglés
    Neurosurgical Neuropsychology: The Practical Application of Neuropsychology in the Neurosurgical Practice comprehensively explains the use of neuropsychology in neurosurgical settings. The book covers various preoperative techniques that may benefit neurosurgeons, such as functional neuroimaging (fMRI, SPECT, MEG) for presurgical cognitive mapping, as well as more traditional methods to predict outcomes after surgery, including neurocognitive testing and the Wada procedure. The book's editors discuss why neuropsychologists add considerable value to the neurosurgical team. A wide range of patient populations are covered, ranging from Deep Brain Stimulation candidates for Parkinson’s disease, to adult and pediatric epilepsy candidates and neuro-oncology cases. This book is ideal for neurosurgeons, neuropsychologists, neuro-oncologists, epileptologists, general neurologists, and others who want to know more about the use of neuropsychology as a tool in the presurgical and postoperative phases of neurosurgery.

  • Genetic Models and Molecular Pathways Underlying Autism Spectrum Disorders

    • 1 Edición
    • Volumen 241
    • Inglés
    Genetic Models and Molecular Pathways Underlying Autism Spectrum Disorders, Volume 241 provides the most recent information on the animal model systems that are available to study different forms of autism spectrum disorders. In addition to genetically engineered animals that uniquely model genetic forms of ASD, this volume also provides detailed chapters on a variety of specific topics, including An overview of genetic models of ASDs, Phenotypic modeling of ASD symptoms, Molecular mechanisms of NF1 model of ASD symptoms, Ube3a gene dosage disorders: molecular and circuit mechanisms of ASD, Circuit dysfunctions in ASD models, ERK signaling in genetic models of ASD, and more.

  • Introduction to Electrophysiological Methods and Instrumentation

    • 2 Edición
    • Franklin Bretschneider + 1 más
    • Inglés
    Introduction to Electrophysiological Methods and Instrumentation, Second Edition covers all topics of interest to electrophysiologists... neuroscientists and neurophysiologists, from the reliable penetration of cells and the behavior and function of the equipment, to the mathematical tools available for analyzing data. It discusses the pros and cons of techniques and methods used in electrophysiology and how to avoid pitfalls. Although the basics of electrophysiological techniques remain the principal purpose of this second edition, it now integrates several current developments, including, amongst others, automated recording for high throughput screening and multimodal recordings to correlate electrical activity with other physiological parameters collected by optical means. This book provides the electrophysiologist with the tools needed to understand his or her equipment and how to acquire and analyze low-voltage biological signals.

  • Imaging in Movement Disorders: Imaging in Atypical Parkinsonism and Familial Movement Disorders

    • 1 Edición
    • Volumen 142
    • Inglés
    Imaging in Movement Disorders: Imaging in Atypical Parkinsonism and Familial Movement Disorders, Volume 142, addresses the use of imaging modalities across the spectrum of movement disorders and dementias. Over the last decades, advances in neuroimaging tools have played a pivotal role in expanding our understanding of disease aetiology and pathophysiology, identifying biomarkers to monitor disease progression, aiding differential diagnosis and in the identification of novel targets for therapeutic intervention. This updated volume covers PET Molecular Imaging in Atypical Parkinsonism, SPECT Molecular Imaging in Atypical Parkinsonism, Structural MRI in Atypical Parkinsonism, Functional MRI in Atypical Parkinsonism, and more.

  • Simulation in Acute Neurology

    • 1 Edición
    • Sara E. Hocker + 1 más
    • Inglés
    Simulation in Acute Neurology is a textbook on the execution of a simulation-based educational program in the management of acute neurologic emergencies. Simulation in Acute Neurology has practical value because it contains detailed descriptions of our simulation scenarios. The foundation of this book is our experience with neurosimulation―and it has been a very good one. Part I provides an overview of the principles of simulation in medicine and examines the many unique opportunities simulation provides as an educational tool. Barriers to simulating neurologic emergencies are also discussed. Simulation allows a physician-in-trainin... to be observed directly as he or she evaluates and manages acute neurologic disease. Part II is the core of the book. Fifteen acute neurologic emergencies, including complex neuroethical quandaries, are presented in detail, step by step, decision by decision, error after error. Each chapter in this section starts with an explanation of the essence of the discussed neuroemergency (THE PROBLEM BEFORE US), followed by a description of the scenario itself (THE PRESENTING CLINICAL PROBLEM), how scenarios can be adjusted to different types of learners (ADAPTING THE SCENARIO), and ends with a discussion of topics for feedback, which are generally focused around errors and pitfalls (DEBRIEFING). To show the flow of scenarios, we created two additional main headings: (THE IDEAL LEARNER) and (THE NOT-SO IDEAL LEARNER).

  • Imaging in Movement Disorders

    Imaging Methodology and Applications in Parkinson's Disease
    • 1 Edición
    • Volumen 141
    • Inglés
    Imaging Methodology and Applications in Parkinson's Disease, Volume 141, provides an up-to-date and comprehensive textbook on the use of imaging modalities across the spectrum of movement disorders and dementias. Over the last decades, advances in neuroimaging tools has played a pivotal role in expanding our understanding of disease etiology and pathophysiology, identifying biomarkers to monitor disease progression, aiding differential diagnosis, and in the identification of novel targets for therapeutic intervention. This book brings together lessons learned from neuroimaging tools in movement disorders, including chapters on Advances in PET Methodology, Advances in MRI Methodology, Advances in SPECT Methodology, Hybrid PET/MRI Methodology, and more.

  • The Opioid System as the Interface between the Brain’s Cognitive and Motivational Systems

    • 1 Edición
    • Volumen 239
    • Inglés
    The Opioid System as the Brain’s Interface between Cognition and Motivation, Volume 239, focuses on the opioid system as the interface between the brain’s cognitive and motivational systems. As the opioid system is widely distributed through the brain, particularly in areas implicated in cognition (hippocampus, prefrontal cortex, claustrum, thalamus) and motivation (hypothalamus, amygdala, pontine nuclei, periaqueductal gray and medulla), this book provides chapters that address ongoing research on topics such as the Brain’s cognitive system, the Brain’s motivational system, Antidepressant prescription patterns, Antidepressant-like effects of opioid receptor modulators, the Behavioral effects of antidepressant and anxiolytic drugs, and more.

  • ADHD Complex

    Practicing Mental Health in Primary Care
    • 1 Edición
    • Harlan Gephart
    • Inglés
    ADHD Complex: Practicing Mental Health in Primary Care, written by Dr. Harlan Gephart, provides a comprehensive review of key subjects of importance for primary care and family practitioners to help them better assess, diagnose, treat, and manage patient populations with ADHD. Dr. Gephart, Emeritus Clinical Professor of Pediatrics at University of Washington, has used his many years of experience and practice with this patient population to put together this helpful guide.

  • Pain Neuroethics and Bioethics

    • 1 Edición
    • Volumen 1
    • Inglés
    The treatment of pain and scientific pursuits to understand the mechanisms underlying pain raise many ethical, legal, and social issues.　For the first time, this edited volume brings together content experts in the fields of pain, pediatrics, neuroscience, brain imaging, bioethics, health humanities, and the law to provide insight into the timely topic of pain neuroethics. This landmark volume of the state of the art exploration of pain neuroethics will be a must read for those interested in the ethical issues in pain research, treatment, and management.

  • Brain Targeted Drug Delivery Systems

    A Focus on Nanotechnology and Nanoparticulates
    • 1 Edición
    • Huile Gao + 1 más
    • Inglés
    Brain Targeted Drug Delivery Systems: A Focus on Nanotechnology and Nanoparticulates provides a guide on nanoparticulates to both academic and industry researchers. The book discusses key points in the development of brain targeted drug delivery, summarizes available strategies, and considers the main problems and pitfalls evidenced in current studies on brain targeted drug delivery systems. As the brain is the most important organ in the human body, and disorders of the central nervous system (CNS) are the most serious threat to human life, this book highlights advances and new research in drug delivery methods to the brain.

  • Animal Models for Examining Social Influences on Drug Addiction

    • 1 Edición
    • Volumen 140
    • Inglés
    Animal Models for Examining Social Influences on Drug Addiction, Volume 140 in the International Review of Neurobiology series, provides insights on social factors that mediate drug addiction. This book discusses current research and projects, with specific chapters focusing on Social Influences on Nicotine-related Behaviors in Rodents, Models of Alcohol Intake in Social Contexts, Social Factors in Ethanol Sensitization, Social Modulation of Heroin Intake, Amphetamines and Social Aspects of Addiction, Amphetamines and Social Aspects of Addiction, Social Models of Cannabis Use, Oxytocin and Rodent Models of Addiction, Social Place Preference and Reward, Social Defeat Stress, and more.

  • Handbook of in Vivo Neural Plasticity Techniques

    A Systems Neuroscience Approach to the Neural Basis of Memory and Cognition
    • 1 Edición
    • Volumen 28
    • Inglés
    Handbook of in Vivo Neural Plasticity Techniques, Volume 28: A Systems Neuroscience Approach to the Neural Basis of Memory and Cognition gives a comprehensive overview of the current methods and approaches that are used to study neural plasticity from a systems neuroscience perspective. In addition, the book offers in-depth methodological advice that provides the necessary foundation for researchers establishing methods and students who need to understand the theoretical and methodological bases of these approaches. This is the ideal resource for anyone new to the study of cognitive and behavioral neuroscience who seeks an introduction to state-of-the-art techniques.

  • Neural Mechanisms of Addiction

    • 1 Edición
    • Mary Torregrossa
    • Inglés
    Neural Mechanisms of Addiction is the only book available that synthesizes the latest research in the field into a single, accessible resource covering all aspects of how addiction develops and persists in the brain. The book summarizes our most recent understanding on the neural mechanisms underlying addiction. It also examines numerous biobehavioral aspects of addiction disorders, such as reinforcement learning, reward, cognitive dysfunction, stress, and sleep and circadian rhythms that are not covered in any other publication. Readers with find the most up-to-date information on which to build a foundation for their future research in this expanding field. Combining chapters from leading researchers and thought leaders, this book is an indispensable guide for students and investigators engaged in addiction research.

  • Neurobiology of the Placebo Effect Part II

    • 1 Edición
    • Volumen 139
    • Inglés
    Neurobiology of the Placebo Effect, Part II, Volume 139, the latest release in the International Review of Neurobiology series, is the second part of a two-volume set that provides the latest placebo studies in clinically relevant models. Specific chapters cover the History of placebo effects in medicine, Lumping or Splitting: Towards a taxonomy of placebo and related effects, Theories and brain mechanisms of placebo analgesia, Pain Modulation: From CPM to placebo and nocebo effects in experimental and clinical pain, Modulation of the motor system by placebo and nocebo effects, and the role of sleep in learning placebo effects, amongst other topics.

  • Goal-Directed Decision Making

    Computations and Neural Circuits
    • 1 Edición
    • Richard W. Morris + 2 más
    • Inglés
    Goal-Directed Decision Making: Computations and Neural Circuits examines the role of goal-directed choice. It begins with an examination of the computations performed by associated circuits, but then moves on to in-depth examinations on how goal-directed learning interacts with other forms of choice and response selection. This is the only book that embraces the multidisciplinary nature of this area of decision-making, integrating our knowledge of goal-directed decision-making from basic, computational, clinical, and ethology research into a single resource that is invaluable for neuroscientists, psychologists and computer scientists alike. The book presents discussions on the broader field of decision-making and how it has expanded to incorporate ideas related to flexible behaviors, such as cognitive control, economic choice, and Bayesian inference, as well as the influences that motivation, context and cues have on behavior and decision-making.

  • Gunner Goggles Neurology

    • 1 Edición
    • Hao-Hua Wu + 1 más
    • Inglés
    The Gunner Goggles Series is the first exam prep resource written by a high-scoring peer group of medical students, ensuring the most practical and efficient study guidance. It organizes topics around the USMLE and NBME content outlines for the required shelf exams and features state-of-the-art Augmented Reality (AR) mobile application to extend learning beyond the book. This innovative series features AR opportunities throughout the text for an integrated print-mobile experience that maximizes learning and test preparation. The Gunner Goggle function allows you to scan pages for integrated AR links, unlocking animations, visuals, and 3D models that clarify complex anatomy, conditions, and concepts in a remarkably effective and unique manner. Gunner Goggles Series: Neurology is one of seven authoritative exam preparation guides that use cutting-edge AR technology to fully prepare you for the NBME clinical shelf exams, the USMLE Step 2 Clinical Knowledge (CK) exam, and successful clinical rotations.

  • Cerebral Lateralization and Cognition: Evolutionary and Developmental Investigations of Behavioral Biases

    • 1 Edición
    • Volumen 238
    • Inglés
    Cerebral Lateralization and Cognition: Evolutionary and Developmental Investigations of Motor Biases, Volume 238, the latest release in the Progress in Brain Research series, discusses interdisciplinary research on the influence of cerebral lateralization on cognition within an evolutionary framework. Chapters of note in this release include Evolutionary Perspectives: Visual/Motor Biases and Cognition, Manual laterality and cognition through evolution: An archeological perspective, Laterality in insects, Motor asymmetries in fish, amphibians and reptiles, Visual biases and social cognition in animals, Mother and offspring lateralized social interaction across animal species, Manual bias, personality and cognition in common marmosets and other primates, and more.

  • Neuro-oncology, An Issue of Neurologic Clinics

    • 1 Edición
    • Volumen 36-3
    • Patrick Y Wen + 1 más
    • Inglés
    This issue of Neurologic Clinics, edited by Drs. Patrick Y. Wen and Eudocia Quant Lee, will focus on Neuro-oncology. Topiocs include, but are not limited to, Epidemiology of brain tumors, Molecular pathogenesis of brain tumors, Changes in WHO classification of brain tumors, Neurologic and medical management of brain tumors, Grade 2 and 3 Gliomas, Glioblastoma, Benign brain tumors, Primary CNS lymphoma and neurologic complications of systemic lymphoma, Pediatric brain tumors, Brain metastases, Metastatic complications of cancer, Neurologic complications of radiation therapy, Neurologic complications of systemic anticancer therapies, Neurocognitive complaints in cancer patients, and Paraneoplastic syndromes.

  • Neuroinflammation

    • 2 Edición
    • Alireza Minagar
    • Inglés
    Neuroinflammation, Second Edition, discusses the role inflammation plays in neuro-inflammatory diseases. As research in neuroinflammation has dramatically increased in recent years, this new edition covers all of the new developments and findings since the first publication nearly a decade ago. Comprehensive coverage of topics includes chapters on multiple sclerosis, optic neuritis and Susac syndrome. New chapters cover the latest research in Epilepsy and Neuroinflammation, Pediatric MS, Pediatric Lupus and Traumatic Brain Injury, amongst other topics. Inflammation is a central mechanism in many neurological diseases, including stroke, multiple sclerosis, brain trauma and meningitis, and it contributes to the generation of pain. Researchers are now beginning to understand the impact of the immune system on different nervous system functions and diseases, ranging from damage, through tolerance, and to modulation and repair.

  • Emergent Neuroimaging: A Patient Focused Approach, An Issue of Neuroimaging Clinics of North America

    • 1 Edición
    • Volumen 28-3
    • Diego B. Nunez
    • Inglés
    This issue of Neuroimaging Clinics of North America focuses on Emergent Neuroimaging: A Patient Focused Approach, and is edited by Dr. Diego B. Nunez. Articles will include: The adult patient with acute neurologic deficit: an update on imaging trends; The patient with thunderclap headache; Imaging considerations in the patient with intracerebral hemorrhage; Emergent neuroimaging in the oncologic and immunosuppressed patient; Emergent neuroimaging during pregnancy and puerperium; Imaging the unconscious “found down” patient in the ED; Neurological emergencies in the pediatric patient including accidental and non-accidental trauma; Head and neck injuries: special considerations in the elderly patient; Current challenges in the use of CT and MRI in suspected cervical spine trauma; Radiation considerations in emergent neuroimaging; Blunt cranio-cervical trauma: Does the patient have a cerebral vascular injury?; New and emerging patient-centered CT imaging and image-guided treatment paradigms for maxillofacial trauma; Acute neurological syndromes beyond stroke: The role of emergent MRI; and more!

  • The Immune System and Mental Health

    • 1 Edición
    • Hymie Anisman + 2 más
    • Inglés
    The Immune System and Mental Health fully investigates how immune-related cellular, molecular and anatomical changes impact mental functioning. The book combines human and animal studies to reveal immunological changes related to mental-health problems. In addition, users will find comprehensive information on new research related to the microbial composition of the gut, aka, the microbiome, and how it influences brain function and mental health. Common comorbidities with mental illness and their inherent immunological or inflammatory components are also covered. Written by leaders in the field, the book synthesizes basic and clinical research to provide a thorough understanding on the role of immunity in neuropsychiatry. Sociology, psychology, psychiatry, neuroscience and genetics have provided considerable explanations and solutions to some of the most intractable mental-health problems. But researchers are increasingly relying on investigations of the immune system to identify factors that can undermine and impair mental health. This book covers devastating mental-health conditions, such as depression, anxiety, schizophrenia, and autism-like spectrum disorders. In addition, degenerative disorders of the brain, such as Parkinson’s and Alzheimer’s-like dementia are explored.

  • Objective Biometric Methods for the Diagnosis and Treatment of Nervous System Disorders

    • 1 Edición
    • Elizabeth B. Torres
    • Inglés
    Objective Biometric Methods for the Diagnosis and Treatment of Nervous System Disorders provides a new and unifying methodological framework, introducing new objective biometrics to characterize patterns of sensory motor control underlying symptoms. Its goal is to radically transform the ways in which disorders of the nervous system are currently diagnosed, tracked, researched and treated. This book introduces new ways to bring the laboratory to the clinical setting, to schools and to settings of occupational and physical therapy. Ready-to-use, graphic user interfaces are introduced to provide outcome measures from wearable sensors that automatically assess in near real time the effectiveness of interventions. Lastly, examples of how the new framework has been effectively utilized in the context of clinical trials are provided.

  • The Neuroscience of Empathy, Compassion, and Self-Compassion

    • 1 Edición
    • Larry Charles Stevens + 1 más
    • Inglés
    The Neuroscience of Empathy, Compassion, and Self-Compassion provides contemporary perspectives on the three related domains of empathy, compassion and self-compassion (ECS). It informs current research, stimulates further research endeavors, and encourages continued and creative philosophical and scientific inquiry into the critical societal constructs of ECS. Examining the growing number of electrocortical (EEG Power Spectral, Coherence, Evoked Potential, etc.) studies and the sizeable body of exciting neuroendocrine research (e.g., oxytocin, dopamine, etc.) that have accumulated over decades, this reference is a unique and comprehensive approach to empathy, compassion and self-compassion.

  • Bipolar Disorder Vulnerability

    Perspectives from Pediatric and High-Risk Populations
    • 1 Edición
    • Jair Soares + 2 más
    • Inglés
    Bipolar Disorder Vulnerability: Perspectives from Pediatric and High-Risk Populations synthesizes our current understanding of high-risk and pediatric populations to aid readers in identifying markers of vulnerability for the development of bipolar disorder, with an ultimate goal of the development of drug targets and other therapies for early diagnosis and treatment. The book provides readers with an understanding of biological and environmental factors influencing disease manifestation that will aid them in defining discrete clinical stages and, importantly, establish an empirical basis for the application of novel therapeutics in a phase of illness during which specific treatments could more effectively alter disease course. Whereas most of the literature available on the pathophysiological mechanisms of bipolar disorder focuses on chronically ill adult individuals, this represents the only book that specifically examines pediatric and high-risk populations. An estimated 30 to 60 percent of adult bipolar disorder patients have their disease onset during childhood, with early-onset cases representing a particularly severe and genetically loaded form of the illness.

  • The Cerebellum: Disorders and Treatment

    Handbook of Clinical Neurology Series
    • 1 Edición
    • Volumen 155
    • Inglés
    The Cerebellum: Disorders and Treatment, Volume 155 updates readers on the latest and clinically relevant advances in the study of cerebellar diseases in children and adults. It is organized into sections detailing: (1) Disorders (starting from the fetal cerebellum, to adult cerebellum) encountered during daily practice, and (2) Therapy (including insights into innovative drug and rehabilitative approaches). The book's innovative structure discusses cerebellar disorders in children and adults as a continuum, with its companion volume, The Cerebellum: From Embryology to Diagnostic Investigations detailing embryology, anatomy, function and diagnostic investigations and neuroimaging, including conventional sequences, diffusion tensor imaging, functional MRI, and connectivity studies.

  • The Cerebellum: From Embryology to Diagnostic Investigations

    Handbook of Clinical Neurology Series
    • 1 Edición
    • Volumen 154
    • Inglés
    The Cerebellum: From Embryology to Diagnostic Investigations, Volume 154 is designed to update the reader on the latest and clinically relevant advances in the study of cerebellar diseases in children and adults. It is organized into sections detailing: (1) Embryology, Anatomy and Function, and (2) Diagnostic investigations: Neuroimaging, and includes content on conventional sequences, diffusion tensor imaging, functional MRI, and connectivity studies. Its companion volume, The Cerebellum: Disorders and Treatment, describes disorders (starting from the fetal cerebellum, to adult cerebellum) encountered during daily practice and therapy (including insights into innovative drug and rehabilitative approaches to treat children and adults with cerebellar disorders).

  • Human Prion Diseases

    • 1 Edición
    • Volumen 153
    • Inglés
    Human Prion Diseases, Volume 153 is designed to update the reader on the latest advances and clinical aspects of prion diseases. The book is organized into five sections, including the pathophysiology of prions and a description of animal and human diseases. This is followed by detailed reports on recent advances in diagnosis strategies for the development of novel anti-prion molecules and possible designs of clinical trials in such a rare disease. An introductory chapter gives an extensive historical background of prion research, with a final chapter highlighting recent progress, and more importantly, unsolved problems.

  • Gene Therapy in Neurological Disorders

    • 1 Edición
    • Mingjie Li + 1 más
    • Inglés
    Gene therapy has tremendous potential for the treatment of neurological disorders. There has been substantial progress in the development of gene therapy strategies for neurological disorders over the last two decades. Gene Therapy in Neurological Disorders thoroughly reviews currently available gene therapy tools and presents examples of their application in a variety of neurological diseases. The book begins with general reviews of gene therapy strategies with a focus on neurological disorders. The remainder of the chapters present approaches to specific neurological disorders. Each chapter gives an in-depth introduction to the relevant field before diving into the specific tool or application. The book aims to help investigators, students and research staff better understand the principles of gene therapy and its application in the nervous system.

  • Linking Environmental Exposure to Neurodevelopmental Disorders

    • 1 Edición
    • Volumen 2
    • Inglés
    Advances in Neurotoxicology, Volume Two, addresses contemporary advances in neurotoxicology, with thematic volumes providing authoritative review articles on key issues in the field. Updates in this new volume include chapters on Air pollution and neurodegenerative diseases, Mercury and Parkinson’s disease, Pesticides and PD: current evidence, Aluminum and neurodegeneration, Microglia and neurodegeneration, Dietary factors, Mitochondria in neurodegeneration, and Manganese and neurodegeneration. Edited by leading experts, volumes are designed as in-depth overviews of the latest topic developments that analyze the effect of varied chemical agents on the nervous system. It is an essential resource for researchers and graduate students alike.

  • Inflammation and Immunity in Depression

    Basic Science and Clinical Applications
    • 1 Edición
    • Bernhard Baune
    • Inglés
    Inflammation and Immunity in Depression: Basic Science and Clinical Applications is the first book to move beyond the established theory of cytokine-induced depression and explore the broader role the immune system plays in this devastating mood disorder. The book fully explores the most recent lines of research into this rapidly advancing field, including alterations of T-cells, the neurobiological implications of neuroinflammation and immune alterations for brain development and function, and the genetic components of neuroinflammation in depression, including the relationships between stress and inflammation that are revealing gene-environment interactions in the disorder. Combining contributions from researchers worldwide, this book provides the most comprehensive discussion available today on the involvement of the innate immune and adaptive immune systems in depressive disorder. Chapters span neuroscience, psychology, clinical applications and future directions, making this book an invaluable resource for advanced students, researchers and practitioners who need to understand the complex and varied role of inflammation and immune responses in depression.

  • Signal Processing in Auditory Neuroscience

    Temporal and Spatial Features of Sound and Speech
    • 1 Edición
    • Yoichi Ando
    • Inglés
    Signal Processing in Auditory Neuroscience: Temporal and Spatial Features of Sound and Speech discusses how the physical attributes of different sounds manifest in neural signals and how to tease-apart their different influences. It includes EEG/MEG as additional variables to be considered when studying neural mechanisms of auditory processing in general, specifically in speech.

  • Intracranial Aneurysms

    • 1 Edición
    • Andrew J. Ringer
    • Inglés
    Intracranial aneurysm result from complex interactions between cerebrovascular anatomy, vascular injury, and adaptive remodeling of the arterial wall and represent a cerebrovascular disorder with the potential for substantial morbidity and mortality. Most intracranial aneurysms occur in the larger arteries near the skull base, in or around the circle of Willis, but variants may appear virtually anywhere in the cerebral vasculature. The aneurysm can leak or rupture, causing life-threatening bleeding, and is the most common cause of spontaneous subarachnoid hemorrhage, the third most common form of stroke. Intracranial aneurysms affect about 1 in 10,000 people per year in the United States (approximately 27,000). Intracranial Aneurysms will address the natural history, biology, and basic management principles and treatment of aneurysms. The chapters also explore the unique features of each type or location of aneurysm while considering the medical, surgical, and endovascular options. Contributions are by members of the Endovascular Neurosurgery Research Group, a group of recognized expert neurosurgeons who specialize in cerebrovascular and endovascular management of aneurysms.

  • Heterogeneity of Function in Numerical Cognition

    • 1 Edición
    • Avishai Henik + 1 más
    • Inglés
    Heterogeneity of Function in Numerical Cognition presents the latest updates on ongoing research and discussions regarding numerical cognition. With great individual differences in the development or function of numerical cognition at neuroanatomical, neuropsychological, behavioral, and interactional levels, these issues are important for the achievement of a comprehensive understanding of numerical cognition, hence its brain basis, development, breakdown in brain-injured individuals, and failures to master mathematical skills. These functions are essential for the proper development of numerical cognition.

  • The Arts and The Brain

    Psychology and Physiology Beyond Pleasure
    • 1 Edición
    • Volumen 237
    • Inglés
    The Arts and the Brain: Psychology and Physiology beyond Pleasure, Volume 237, combines the work of an excellent group of experts who explain evidence on the neural and biobehavioral science of the arts. Topics covered include the emergence of early art and the evolution of human culture, the interaction between cultural and biological evolutionary processes in generating artistic creation, the nature of the aesthetic experience of art, the arts as a multisensory experience, new insights from the neuroscience of dance, a systematic review of the biological impact of music, and more.

  • Neurobiology of Abnormal Emotion and Motivated Behaviors

    Integrating Animal and Human Research
    • 1 Edición
    • Susan Sangha + 1 más
    • Inglés
    Neurobiology of Abnormal Emotion and Motivated Behaviors: Integrating Animal and Human Research pulls together world-renowned leaders from both animal and human research, providing a conceptual framework on how neuroscience can inform our understanding of emotion and motivation, while also outlining methodological commonalities between animal and human neuroscience research, with an emphasis on experimental design, physiological recording techniques and outcome measures. Typically, researchers investigating the neurobiology of emotions focus on either animal models or humans. This book brings the two disciplines together to share information and collaborate on future experimental techniques, physiological measures and clinical outcomes.

  • The Auditory System in Sleep

    • 2 Edición
    • Ricardo Velluti
    • Inglés
    The Auditory System in Sleep, Second Edition presents a view of a sensory system working in a different state, that of the sleeping brain. This updated edition contains new chapters on topics such as implanted deaf patients and sleep and tinnitus treatments. It is written for basic auditory system and sleep researchers, as well as practitioners and clinicians in the Auditory/Sensory Neurosciences and Sleep Medicine. As the auditory system is always “open”, thus receiving information from the environment and the body itself (conscious and unconscious data), the incoming sensory information may alter sleep and waking physiology, and conversely, the sleeping brain. This book draws information from evoked potentials, fMRI, PET, SPECT, lesions, and more.

  • Neurobiology of the Placebo Effect, Part I

    • 1 Edición
    • Volumen 138
    • Inglés
    Neurobiology of the Placebo Effect, Part I, Volume 138 in the International Review of Neurobiology series, is the first of two volumes that provide the latest placebo studies in clinically relevant models. Placebo responses effects are not merely a psychological, but a complex psycho-neuro-biologi... process that requires activation of distinct brain areas. This book discusses current research and projects on the involved brain circuitry and neurotransmitter systems. Specific chapters cover such topics as pharmacological conditioning of the endocrine and immune system, expectancy modulation of opioid neurotransmission, nocebo effects in visceral pain, and conditioning as a higher-order cognitive phenomenon, amongst other topics.

  • Signal Processing for Neuroscientists

    • 2 Edición
    • Wim van Drongelen
    • Inglés
    Signal Processing for Neuroscientists, Second Edition provides an introduction to signal processing and modeling for those with a modest understanding of algebra, trigonometry and calculus. With a robust modeling component, this book describes modeling from the fundamental level of differential equations all the way up to practical applications in neuronal modeling. It features nine new chapters and an exercise section developed by the author. Since the modeling of systems and signal analysis are closely related, integrated presentation of these topics using identical or similar mathematics presents a didactic advantage and a significant resource for neuroscientists with quantitative interest. Although each of the topics introduced could fill several volumes, this book provides a fundamental and uncluttered background for the non-specialist scientist or engineer to not only get applications started, but also evaluate more advanced literature on signal processing and modeling.

  • Neuromuscular Junction Disorders, An Issue of Neurologic Clinics

    • 1 Edición
    • Volumen 36-2
    • Mazen M. Dimachkie + 1 más
    • Inglés
    This issue of Neurologic Clinics, edited by Dr. Mazen M. Dimachkie and Dr. Richard J. Barohn, focuses on Neuromuscular Junction Disorders. Topics include--but are not limited to--History of myasthenia gravis and neuromuscular junction disorders; Practical immunology of the neuromuscular junction; Practical anatomy of the neuromuscular junction in health and disease; Generalized myasthenia gravis; Ocular myasthenia gravis; Diagnosis of myasthenia gravis; MuSK and myasthenia gravis due to other autoantibodies; Treatment of myasthenia gravis; Evidenced-based approach of thymectomy for myasthenia gravis; Myasthenia gravis and pregnancy; Congenital myasthenic syndromes; Botulism; Lambert-Eaton myasthenic syndrome; and Measuring clinical treatment response in myasthenia gravis.

  • Imaging of Salivary Glands, An Issue of Neuroimaging Clinics of North America

    • 1 Edición
    • Volumen 28-2
    • Ahmed Abdel Khalek Abdel Razek
    • Inglés
    This issue of Neuroimaging Clinics of North America focuses on Imaging of Salivary Glands, and is edited by Dr. Ahmed Abdel Khalek Abdel Razek. Articles will include: Cross sectional imaging techniques and normal anatomy of the salivary glands; Imaging of benign salivary gland tumors; Imaging of cancer salivary glands; Imaging of Sjögren's syndrome and immunoglobulin g4-related disorder of salivary glands; Imaging of post treatment of salivary glands; Imaging of pediatric salivary glands; Imaging of submandibular and sublingual salivary glands; Scintigraphy and PET of salivary glands; Imaging of inflammatory disorders of salivary glands; Routine and advanced ultrasound of salivary glands; and more!

  • The Neurology of HIV Infection

    • 1 Edición
    • Volumen 152
    • Inglés
    The Neurology of HIV Infection covers all aspects of nervous system involvement and pathology in HIV-infected individuals. Specialists in this field cover epidemiology, global aspects, pathology and pathogenesis of nervous system disease in HIV-infection. All complications, including the pathology caused by HIV itself and all opportunistic infections of the nervous system are reviewed in detail. Both central nervous and peripheral nervous system complications, including neuropathies and myopathies, are discussed. Key chapters on global developments, HIV-associated neurocognitive disorders, IRIS, stroke and neuro-aids in children complete this volume.

  • The Molecular and Cellular Basis of Neurodegenerative Diseases

    Underlying Mechanisms
    • 1 Edición
    • Michael S. Wolfe
    • Inglés
    The Molecular and Cellular Basis of Neurodegenerative Diseases: Underlying Mechanisms presents the pathology, genetics, biochemistry and cell biology of the major human neurodegenerative diseases, including Alzheimer’s, Parkinson’s, frontotemporal dementia, ALS, Huntington’s, and prion diseases. Edited and authored by internationally recognized leaders in the field, the book's chapters explore their pathogenic commonalities and differences, also including discussions of animal models and prospects for therapeutics. Diseases are presented first, with common mechanisms later. Individual chapters discuss each major neurodegenerative disease, integrating this information to offer multiple molecular and cellular mechanisms that diseases may have in common. This book provides readers with a timely update on this rapidly advancing area of investigation, presenting an invaluable resource for researchers in the field.

  • Handbook of Brain Tumor Chemotherapy, Molecular Therapeutics, and Immunotherapy

    • 2 Edición
    • Herbert B. Newton
    • Inglés
    Handbook of Brain Tumor Chemotherapy, Molecular Therapeutics, and Immunotherapy, Second Edition, provides a comprehensive overview of the molecular methodologies in the neuro-oncology field. There have been profound changes in the landscape of approaches to brain tumor therapy since the first edition—mainly in the areas of molecular biology and molecular therapeutics, as well as in the maturation of immunotherapy approaches (e.g., vaccines). This updated edition has a new, primary focus on multidisciplinary molecular methods, and is broadened to include the latest cutting-edge molecular biology, therapeutics, immunobiology and immunotherapy approaches. As the first comprehensive book to address the molecular research into these concepts, users will find it to be an invaluable resource on the topics discussed.

  • Ischemic and Traumatic Brain and Spinal Cord Injuries

    Mechanisms and Potential Therapies
    • 1 Edición
    • Akhlaq A. Farooqui
    • Inglés
    Ischemic and Traumatic Brain and Spinal Cord Injuries: Mechanisms and Potential Therapies presents readers with comprehensive and cutting-edge information on molecular mechanisms, including the signal transduction processes associated with neurodegeneration and neuroprotection in ischemic, spinal cord, severe and mild brain injuries. The book also covers the molecular mechanisms of drugs used for the treatment of neurotraumatic disease. Chapters are organized by molecular aspects and neuroprotective strategies by disease, including ischemic injury, spinal cord injury, traumatic brain injury, and chronic traumatic encephalopathy. The book integrates and consolidates knowledge on neurotraumatic diseases, with the hope of bringing forth more dramatic advances and developments, not only on molecular mechanisms, but also on the causes of, and treatments for, neurotraumatic diseases.

  • Neuronal Correlates of Empathy

    From Rodent to Human
    • 1 Edición
    • Ksenia Z. Meyza + 1 más
    • Inglés
    Neuronal Correlates of Empathy: From Rodent to Human explores the neurobiology behind emotional contagion, compassionate behaviors and the similarities in rodents and human and non-human primates. The book provides clear and accessible information that avoids anthropomorphisms, reviews the latest research from the literature, and is essential reading for neuroscientists and others studying behavior, emotion and empathy impairments, both in basic research and preclinical studies. Though empathy is still considered by many to be a uniquely human trait, growing evidence suggests that it is present in other species, and that rodents, non-human primates, and humans share similarities.

  • Fundamentals of Cognitive Neuroscience

    A Beginner's Guide
    • 2 Edición
    • Nicole M. Gage + 1 más
    • Inglés
    Fundamentals of Cognitive Neuroscience: A Beginner's Guide, Second Edition, is a comprehensive, yet accessible, beginner’s guide on cognitive neuroscience. This text takes a distinctive, commonsense approach to help newcomers easily learn the basics of how the brain functions when we learn, act, feel, speak and socialize. This updated edition includes contents and features that are both academically rigorous and engaging, including a step-by-step introduction to the visible brain, colorful brain illustrations, and new chapters on emerging topics in cognition research, including emotion, sleep and disorders of consciousness, and discussions of novel findings that highlight cognitive neuroscience’s practical applications. Written by two leading experts in the field and thoroughly updated, this book remains an indispensable introduction to the study of cognition.

  • The Parietal Lobe

    • 1 Edición
    • Volumen 151
    • Inglés
    The Parietal Lobe, Volume 151, the latest release from the Handbook of Clinical Neurology series, provides a foundation on the neuroanatomy, neurophysiology and clinical neurology/neuropsych... of the parietal lobe that is not only applicable to both basic researchers and clinicians, but also to students and specialists who are interested in learning more about disorders brought on by damage or dysfunction. Topics encompass the evolution, anatomy, connections, and neurophysiology, the major neurological and neuropsychological deficits and syndromes caused by damage, the potential for improvement via transcranial stimulation, and the role of the parietal in the cerebral networks for perception and action.

  • Brain Banking

    • 1 Edición
    • Volumen 150
    • Inglés
    Brain Banking, Volume 150, serves as the only book on the market offering comprehensive coverage of the functional realities of brain banking. It focuses on brain donor recruitment strategies, brain bank networks, ethical issues, brain dissection/tissue processing/tissue dissemination, neuropathological diagnosis, brain donor data, and techniques in brain tissue analysis. In accordance with massive initiatives, such as BRAIN and the EU Human Brain Project, abnormalities and potential therapeutic targets of neurological and psychiatric disorders need to be validated in human brain tissue, thus requiring substantial numbers of well characterized human brains of high tissue quality with neurological and psychiatric diseases.

  • Quality and Safety in Neurosurgery

    • 1 Edición
    • Daniel J. Guillaume + 1 más
    • Inglés
    Quality and Safety in Neurosurgery covers recent improvements and presents solutions for problems that impact patient care. This book is written for anyone who works at the intersection of quality, safety and neurosurgery, including neurosurgeons, neurologists, clinical researchers looking to improve outcomes in neurosurgery, hospital quality and safety officers, department leaders, fellows and residents. Edited by neurosurgeons who helped build the culture of quality and safety in the Department of Neurosurgery at UMN, this work emphasizes quality and safety, whether through ‘value based purchasing’, finding specialty specific quality and safety metrics, or just the professional desire to provide quality care.

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