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Elsevier

Libros en Neurociencia

  • Institutional Neurosis

    • 2 Edición
    • Russell Barton
    • Inglés
    Institutional Neurosis is a four-chapter text that systematically presents the dreadful mental changes that may result from institutional life and the steps that can be taken to cure them. The term “institutional neurosis” promotes the syndrome to the category of a disease, rather than a process, thereby encouraging the public to understand, approach, and deal with it in the same way as other diseases. The opening chapter describes the clinical features of the disorder in mental hospitals, its differential diagnosis, etiology, treatment, and prevention. The next chapters consider the etiology or factors associated with institutional neurosis, including apathy, loss of interest, lack of initiative, and sometimes a characteristic posture and gait. The last chapter reviews the various aspects of the treatment of institutional neurosis. This book is of value to neurologists, psychologists, psychiatrists, and researchers in the allied fields.

  • Sport and the Brain: The Science of Preparing, Enduring and Winning, Part A

    • 1 Edición
    • Volumen 232
    • Inglés
    Sport and the Brain: The Science of Preparing, Enduring and Winning, Part A, Volume 231 reflects recent advancements in the understanding of how elite athletes prepare for—and perform at—peak levels during competition. The latest release in this series focuses on a variety of topics, including chapters on Great British medalists: Psychosocial biographies of Super-Elite and Elite athletes from Olympic sports, a chapter on elite and super-elite Great British athletes: Some theoretical implications from Hardy et al.’s (2016) findings, and The psychosocial development of world class athletes: Additional considerations for understanding the whole person and salience of adversity. This series takes a multidisciplinary approach, focusing on aspects of psychology, neuroscience, skill learning, talent development and physiology.

  • The Rewiring Brain

    A Computational Approach to Structural Plasticity in the Adult Brain
    • 1 Edición
    • Arjen van Ooyen + 1 más
    • Inglés
    The adult brain is not as hard-wired as traditionally thought. By modifying their small- or large-scale morphology, neurons can make new synaptic connections or break existing ones (structural plasticity). Structural changes accompany memory formation and learning, and are induced by neurogenesis, neurodegeneration and brain injury such as stroke. Exploring the role of structural plasticity in the brain can be greatly assisted by mathematical and computational models, as they enable us to bridge the gap between system-level dynamics and lower level cellular and molecular processes. However, most traditional neural network models have fixed neuronal morphologies and a static connectivity pattern, with plasticity merely arising from changes in the strength of existing synapses (synaptic plasticity). In The Rewiring Brain, the editors bring together for the first time contemporary modeling studies that investigate the implications of structural plasticity for brain function and pathology. Starting with an experimental background on structural plasticity in the adult brain, the book covers computational studies on homeostatic structural plasticity, the impact of structural plasticity on cognition and cortical connectivity, the interaction between synaptic and structural plasticity, neurogenesis-related structural plasticity, and structural plasticity in neurological disorders. Structural plasticity adds a whole new dimension to brain plasticity, and The Rewiring Brain shows how computational approaches may help to gain a better understanding of the full adaptive potential of the adult brain. The book is written for both computational and experimental neuroscientists.

  • Psychometrics and Psychological Assessment

    Principles and Applications
    • 1 Edición
    • Carina Coulacoglou + 1 más
    • Inglés
    Psychometrics and Psychological Assessment: Principles and Applications reports on contemporary perspectives and models on psychological assessment and their corresponding measures. It highlights topics relevant to clinical and neuropsychological domains, including cognitive abilities, adaptive behavior, temperament, and psychopathology.More... the book examines a series of standard as well as novel methods and instruments, along with their psychometric properties, recent meta-analytic studies, and their cross-cultural applications.

  • Models of Seizures and Epilepsy

    • 2 Edición
    • Asla Pitkänen + 3 más
    • Inglés
    Models of Seizures and Epilepsy, Second Edition, is a valuable, practical reference for investigators who are searching for the most appropriate laboratory models to address key questions in the field. The book also provides an important background for physicians, fellows, and students, offering insight into the potential for advances in epilepsy research as well as R&D drug development. Contents include the current spectrum of models available to model different epilepsy syndromes, epilepsy in transgenic animals, comorbidities in models of epilepsy, and novel technologies to study seizures and epilepsies in animals.

  • Essentials of Noncoding RNA in Neuroscience

    Ontogenetics, Plasticity of the Vertebrate Brain
    • 1 Edición
    • Davide De Pietri Tonelli
    • Inglés
    Essentials of Noncoding RNA in Neuroscience: Ontogenetics, Plasticity of the Vertebrate Brain focuses on the role of miRNAs in neurogenesis, gliogenesis, neuronal network formation, and the cell biology of forebrain development. The important role miRNAs play in neuronal maturation, neocortex function, and in some neurodevelopmental disorders is discussed, as are the computational challenges and methods used in the identification of miRNA targets. This book is a valuable reference for neuroscientists who wish to better understand the role of miRNAs in complex processes. It is of strong interest to those working to develop enabling technologies to detect and monitor miRNA expression and function, and to evaluate its roles in neural progenitor proliferation/differ... neuronal plasticity, and learning and memory.

  • Choroidal Disorders

    • 1 Edición
    • Jay Chhablani + 1 más
    • Inglés
    Choroidal Disorders provides an overview on various chorioretinal disorders with a special emphasis on choroidal imaging. As our understanding of the choroid has significantly improved with the development of advanced optical coherence tomography (OCT) and its role in posterior segment diseases is gaining new significance, this book focuses on the related improvements, diagnostic capabilities, management and prognosis of various chorioretinal disorders. It covers conventional techniques, such as ultrasonography and indocyanine green angiography as well as the most advanced techniques, including enhanced depth imaging OCT, swept source OCT, and OCT angiography.

  • Parkinson's Disease

    • 1 Edición
    • Volumen 132
    • Inglés
    Parkinson's Disease, Volume 132 addresses new developments in the F33 study of this disease, highlighting how the lives of people with Parkinson’s have undergone dramatic changes in the last decade. New to this edition are chapters on the Hallmarks of clinical aspects PD throughout centuries, The motor syndrome of Parkinson disease, The non-motor features of Parkinson’s disease, The New Diagnostic Criteria for Parkinson's disease, Advances in the Clinical Differential diagnosis, Clinical assessments in PD : Scales and monitoring, Biomarkers of Parkinson’s disease: an Introduction, and the Genetics of Parkinson’s Disease: Genotype-Phenotype Correlations. The topics discussed in this comprehensive series provide a clearer understanding of the prodromal stage, genetics, strategies, routes of treatment, and development of non-dopaminergic therapies in Parkinson's Disease, both medical and surgical.

  • Functional Neural Transplantation IV

    Translation to Clinical Application, Part B
    • 1 Edición
    • Volumen 231
    • Inglés
    Functional Neural Transplantation IV: Translation to Clinical Application, Part B, Volume 231 provides the current status of cell transplantation in the nervous system, focusing on the conditions for achieving structural repair and functional recovery. New to this edition are chapters on Plasticity and Regeneration in the Injured Spinal Cord After Cell Transplantation Therapy, Transplantation of GABAergic Interneurons for Cell-Based Therapy, Rebuilding CNS Inhibitory Circuits to Control Chronic Neuropathic Pain and Itch, From Transplanting Schwann Cells in Experimental Rat Spinal Cord Injury to their Transplantation into Human Injured Spinal Cord in Clinical Trials, and the Recruitment of Endogenous CNS Stem Cells for Regeneration in Demyelinating Disease. As the fourth in a periodic series of updates at 5-7 year intervals, this volume highlights recent developments in cellular and molecular science, providing the fundamental principles of neuroplasticity and regeneration in the brain and spinal cord, while also addressing the power of pluripotent stem cells to generate new sources of precisely specified neurons for utilization in brain repair.

  • Fragile X Syndrome

    From Genetics to Targeted Treatment
    • 1 Edición
    • Rob Willemsen + 1 más
    • Inglés
    Fragile X Syndrome: From Genetics to Targeted Treatment provides a structured overview of the molecular and clinical background of the disorder as well as treatment options. The book discusses the detailed molecular information on each of the pathways involved with sufficient details for all whose research touches this pathway. It provides a state-of-the-art update on all clinical aspects associated with this syndrome, including phenotype, diagnostics and epidemiology. It also includes an overview of the lessons learned from the preclinical research and pioneering trials on the fragile X syndrome for the investigators involved in clinical trials of neurodevelopmental disorders. This book is written for academic researchers, pharmaceutical investigators, and clinicians in the field who work on the disorder, and for researchers involved in clinical trials of the fragile X syndrome or related disorders. “This fascinating book, edited by Rob Willemsen and Frank Kooy, summarizes the current knowledge of the molecular aspects of fragile X syndrome (FXS), andthe potential for therapies resulting from this knowledge...Particul... interesting is a review “fragile X research from a parental perspective,” which summarizes the results of an international survey of the attitudes of families with FXS relatives towards research…This book is also an essential reference book for genetic counselors...The book provides counselors with the necessary biological background for proper explanations to the relatives of FXS patients. Many parents acquire a substantial knowledge of the conditions afflicting their children. The book will be helpful for both families and counselors to manage the expectations of families participating in clinical trials…In conclusion, this book is essential for everyone who is involved in the diagnosis and treatment of FXS patients.” - European Journal of Human Genetics (September 2018)

  • Neuroscience Basics

    A Guide to the Brain's Involvement in Everyday Activities
    • 1 Edición
    • Jennifer L. Larimore
    • Inglés
    Neuroscience Basics: A Guide to the Brain’s Involvement in Everyday Activities examines how our brain works in everyday activities like sleeping, eating, love, and exercise. Many want to better understand how the brain works, but the terminology and jargon of books can be overwhelming. The book covers the basics taught in an introductory neurobiology course designed for anyone new to the neuroscience field, including non-neuroscientists. While each of the chapters explore the brain in a normal state, Neuroscience Basics also discusses disruptions of the normal state—psychosis, Alzheimer’s, Parkinson’s, autism, learning disorders, etc. This book breaks down the topics into language that is more accessible while making the neuroscience topics fun and relevant.

  • Neurochemical Aspects of Alzheimer's Disease

    Risk Factors, Pathogenesis, Biomarkers, and Potential Treatment Strategies
    • 1 Edición
    • Akhlaq A. Farooqui
    • Inglés
    Neurochemical Aspects of Alzheimer's Disease provides a comprehensive overview of molecular aspects of risk factors, pathogenesis, biomarkers, and therapeutic strategies. The book focuses on molecular mechanisms and signal transduction processes associated with the pathogenesis, biomarkers, and therapeutic strategies of AD. The comprehensive and cutting edge information in this monograph may not only help in early detection of AD, but also promote discovery of new drugs to treat this chronic disease. Chapters discuss involvement of neural membrane phospholipids, sphingolipids, and cholesterol-derived lipid mediators, abnormal APP processing, and nucleic acid damage, risk factors, biomarker, and therapeutic strategies of Alzheimer's disease. This book is written for neurologists, neuroscientists, neurochemists, neuropharmacologists... and clinicianswho are interested in molecular mechanisms associated with the pathogenesis of age-related neurological disorders.

  • Designing EEG Experiments for Studying the Brain

    Design Code and Example Datasets
    • 1 Edición
    • Aamir Saeed Malik + 1 más
    • Inglés
    Designing EEG Experiments for Studying the Brain: Design Code and Example Datasets details the design of various brain experiments using electroencephalogram (EEG). Providing guidelines for designing an EEG experiment, it is primarily for researchers who want to venture into this field by designing their own experiments as well as those who are excited about neuroscience and want to explore various applications related to the brain. The first chapter describes how to design an EEG experiment and details the various parameters that should be considered for success, while remaining chapters provide experiment design for a number of neurological applications, both clinical and behavioral. As each chapter is accompanied with experiment design codes and example datasets, those interested can quickly design their own experiments or use the current design for their own purposes. Helpful appendices provide various forms for one’s experiment including recruitment forms, feedback forms, ethics forms, and recommendations for related hardware equipment and software for data acquisition, processing, and analysis.

  • Functional Neural Transplantation IV

    Translation to Clinical Application, Part A
    • 1 Edición
    • Volumen 230
    • Inglés
    Functional Neural Transplantation IV: Translation to Clinical Application, Volume 230 provides the current status of cell transplantation in the nervous system, with a focus on the conditions for achieving structural repair and functional recovery after brain damage or in neurodegenerative disease. New to this release are chapters that delve into the Mechanisms and Use of Neural Transplants for Brain Repair, Reprogramming of Somatic Cells: iPS and iN Cells, Brain Repair from Intrinsic Cell Sources: Turning Reactive Glia into Neurons, and Ex Vivo Gene Therapy for the Treatment of Neurological Disorders, Preparation, Characterization and Banking of Clinical-grade Cells for Neural Transplantation. As the fourth in a periodic series of updates at 5-7 year intervals, this volume highlights recent developments related to the application of advances in cellular and molecular science, providing an understanding of the fundamental principles of neuroplasticity and regeneration in the brain and spinal cord, and also addressing the topic of the power of pluripotent stem cells to generate new sources of precisely specified neurons for utilization in brain repair.

  • Arteriovenous and Cavernous Malformations

    • 1 Edición
    • Volumen 143
    • Inglés
    Arteriovenous and Cavernous Malformations, Volume 143, is the latest addition in the ongoing HCN series, an evidence-based compendium which addresses both the scientific and clinical aspects of this unique disease process. The volume covers didactic aspects, such as the epidemiology, etiology, and diagnosis of AVMs, while also providing expert clinical information on the management and treatment of these lesions. In addition, it provides coverage of modern-day advances in the genetics of cavernous malformations, as well as discussion regarding future open research questions. Readers from the laboratory bench to the bedside can expect a broad, yet objective, review of this pathology, with updates from the latest scientific literature and data supporting current practices.

  • The Neuroscience of Cocaine

    Mechanisms and Treatment
    • 1 Edición
    • Victor R. Preedy
    • Inglés
    The Neuroscience of Cocaine: Mechanisms and Treatment explores the complex effects of this drug, addressing the neurobiology behind cocaine use and the psychosocial and behavioral factors that impact cocaine use and abuse. This book provides researchers with an up-to-date understanding of the mechanisms behind cocaine use, and aids them in deriving new pharmacological compounds and therapeutic regimens to treat dependency and withdrawal symptoms. Cocaine is one of the most highly abused illicit drugs worldwide and is frequently associated with other forms of drug addiction and misuse, but researchers are still struggling to understand cocaine’s neuropharmacological profile and the mechanisms of its effects and manifestations at the cognitive level. Cessation of cocaine use can lead to numerous adverse withdrawal conditions, from the cellular and molecular level to the behavioral level of the individual user. Written by worldwide experts in cocaine addiction, this book assists neuroscientists and other addiction researchers in unraveling the many complex facets of cocaine use and abuse.

  • The Endocannabinoid System

    Genetics, Biochemistry, Brain Disorders, and Therapy
    • 1 Edición
    • Eric Murillo-Rodriguez
    • Inglés
    The Endocannabinoid System: Genetics, Biochemistry, Brain Disorders, and Therapy examines the cellular, biochemical, genetic, and therapeutic aspects of the endocannabinoid system. The chapters cover significant conceptual advances in the endocannabinoid field and shed light on the many brain disorders in which this biological system is involved. Written by world-leading experts in the field, the topics covered in this book will have a positive impact on the area of molecular biology, including, but not limited to, cell biology, neuroscience, pharmacology, signaling, disease mechanisms, and therapeutics.

  • Biometals in Neurodegenerative Diseases

    Mechanisms and Therapeutics
    • 1 Edición
    • Anthony R. White + 3 más
    • Inglés
    Biometals in Neurodegenerative Diseases: Mechanisms and Therapeutics is an authoritative and timely resource bringing together the major findings in the field for ease of access to those working in the field or with an interest in metals and their role in brain function, disease, and as therapeutic targets. Chapters cover metals in Alzheimer’s Disease, Parkinson’s Disease, Motor Neuron Disease, Autism and lysosomal storage disorders. This book is written for academic researchers, clinicians and advanced graduate students studying or treating patients in neurodegeneration, neurochemistry, neurology and neurotoxicology. The scientific literature in this field is advancing rapidly, with approximately 300 publications per year adding to our knowledge of how biometals contribute to neurodegenerative diseases. Despite this rapid increase in our understanding of biometals in brain disease, the fields of biomedicine and neuroscience have often overlooked this information. The need to bring the research on biometals in neurodegeneration to the forefront of biomedical research is essential in order to understand neurodegenerative disease processes and develop effective therapeutics.

  • Blanco's Overview of Alpha-1 Antitrypsin Deficiency

    History, Biology, Pathophysiology, Related Diseases, Diagnosis and Treatment
    • 1 Edición
    • Ignacio Blanco
    • Inglés
    Blanco’s Overview of Alpha-1 Antitrypsin Deficiency: History, Biology, Pathophysiology, Related Diseases, Diagnosis, and Treatment is a robust introduction to topics associated with Alpha-1 Antitrypsin Deficiency (AATD). Included are topics ranging from the history of the disease, biology, pathophysiology, related diseases, including the two major manifestations of the disease (liver disease and lung disease), and diagnosis and treatment. The book addresses the need for the amalgamation of current and novel concepts and practices in the field of AATD. AATD is under-recognized in the medical community and, as a result, it is underdiagnosed. The book provides increased awareness and understanding of the condition to improve diagnosis rates and enhance patient care. This book is an essential tool and reference, beneficial to clinicians who screen and treat AATD patients, as well as research scientists working in the AATD field at junior and senior levels.

  • A Roadmap for Curing Cancer, Alzheimer's, and Cardiovascular Disease

    • 1 Edición
    • Paul J. Marangos
    • Inglés
    Cancer, dementia, and cardiovascular disease are responsible for almost two million deaths each year in the United States alone and represent the largest immediate threat to humanity. Over the last century, we have made spectacular advances that have transformed our society – splitting the atom, space travel, telecommunications, and the Internet – but with medical research focused mostly on science for the sake of science, it has yielded precious few cures. A Roadmap for Curing Cancer, Alzheimer’s, and Cardiovascular Disease represents a "first of its kind" effort to address both the reasons for this and to posit solutions to fix our broken system, in an effort to finally end this cure crisis. Dr. Marangos draws on 45 years of experience in every aspect of the biomedical R&D field, from basic drug discovery research at the NIH to the co-founding of five drug companies. He has published 252 research papers and edited four books on drug discovery, is co-inventor on 14 patents, and founded "The Journal of Molecular Neuroscience". He argues that from a development perspective, the regulatory, patent, and legal hurdles that force industry to pursue so-called "me-too" drugs rather than cures for terminal diseases must be re-thought. Leadership accountability, strategy, focus, and urgency need to be re-evaluated, and major reforms to the NIH, FDA, and patent codes are proposed.to remedy these impediments to cures. Written for anyone frustrated with the seemingly endless threat of terminal disease, this book seeks to inform, energize, and provide the rationale for the public and industry stakeholders, as well as clinicians and researchers, to resurrect the physician-patient relationship and demand that we get serious about ridding society of this scourge on humanity. This work contains the views and opinions of the author and are in no way intended to harm the reputation of any person, agency, organization, or commercial entity discussed herein. www.cureterminaldise...

  • Brain-Based Learning and Education

    Principles and Practice
    • 1 Edición
    • Yi-Yuan Tang
    • Inglés
    Brain-Based Learning and Education presents a new type of education that uses brain-based and self-control theory-driven training. Leaving aside the current focus in education on content knowledge, it examines essential character strengths such as selfcontrol, persistence, creativity, attention, memory, and social learning, and relates their relevance to learning. By bridging the research and application gap in education, this text not only covers the latest findings related to learning and teaching but also provides insights for application and practice for brain-based methods in health and education. This integration of neuroscience and education takes us from a deep understanding of brain function to the frontline of the classroom.

  • Dementia, An Issue of Neurologic Clinics

    • 1 Edición
    • Volumen 35-2
    • John M. Ringman
    • Inglés
    This issue of Neurologic Clinics, edited by Dr. John Ringman, will cover a wider variety of topics and the latest updated on Demantia. Topics covered in this issue include, but are not limited to Updates on the basic science of AD; The role of neuropsychology in the assessment of the cognitively impaired elderly; Assessment of the Spanish-speaking cognitively impaired elderly; Early-Onset Alzheimer’s disease; Vascular dementia and vascular contributions to Alzheimer’s disease; Frontotemporal Degenerations; and Current and Experimental Treatments, among others.

  • Wilson Disease

    • 1 Edición
    • Volumen 142
    • Anna Czlonkowska + 1 más
    • Inglés
    Wilson Disease provides a comprehensive guide on this inherited genetic disorder that has devastating consequences for both the liver and neurologic/psychiatr... health. This disease is of increasing interest to neurologists, hepatologists, and geneticists, but when the disease is diagnosed early, it is treatable, with patients living normal lives. This volume describes the molecular pathophysiology of WD and the clinical and pathological effects of copper. Separate sections address both diagnosis and medical and surgical approaches to treatment. Both adult and pediatric perspectives on diagnosis and treatment are addressed, and a section on genetics highlights advances in molecular diagnostics. Patient support groups that can aid in coping with this disease are also discussed, as are animal models for those interested in basic research on cell biology, pathophysiology, and treatment.

  • Machine Dreaming and Consciousness

    • 1 Edición
    • J. F. Pagel + 1 más
    • Inglés
    Machine Dreaming and Consciousness is the first book to discuss the questions raised by the advent of machine dreaming. Artificial intelligence (AI) systems meeting criteria of primary and self-reflexive consciousness are often utilized to extend the human interface, creating waking experiences that resemble the human dream. Surprisingly, AI systems also easily meet all human-based operational criteria for dreaming. These “dreams” are far different from anthropomorphic dreaming, including such processes as fuzzy logic, liquid illogic, and integration instability, all processes that may be necessary in both biologic and artificial systems to extend creative capacity. Today, multi-linear AI systems are being built to resemble the structural framework of the human central nervous system. The creation of the biologic framework of dreaming (emotions, associative memories, and visual imagery) is well within our technical capacity. AI dreams potentially portend the further development of consciousness in these systems. This focus on AI dreaming raises even larger questions. In many ways, dreaming defines our humanity. What is humanly special about the states of dreaming? And what are we losing when we limit our focus to its technical and biologic structure, and extend the capacity for dreaming into our artificial creations? Machine Dreaming and Consciousness provides thorough discussion of these issues for neuroscientists and other researchers investigating consciousness and cognition.

  • Advances in Imaging of Multiple Sclerosis, An Issue of Neuroimaging Clinics of North America

    • 1 Edición
    • Volumen 27-2
    • Alex Rovira
    • Inglés
    This issue of Neuroimaging Clinics of North America focuses on Imaging of Multiple Sclerosis: Diagnosis and Management, and is edited by Dr. Àlex Rovira Cañellas. Articles will include: Multiple Sclerosis: Epidemiological, Clinical and Therapeutic Aspects; Brain and Spinal Cord MR Imaging Features in Multiple Sclerosis and Variants; Neuromyelitis Optica Spectrum Disorders; Radiologically Isolated Syndrome; MRI in Monitoring and Predicting Treatment Response in Multiple Sclerosis; Cortical Grey Matter MR Imaging in Multiple Sclerosis; Brain Atrophy in Multiple Sclerosis: Technical Aspects and Clinical Relevance; Iron Mapping in Multiple Sclerosis; Microstructural MR Techniques in Multiple Sclerosis; Molecular and Metabolic Imaging in Multiple Sclerosis; Insights from Ultra-high Field Imaging in Multiple Sclerosis; Pediatric Multiple Sclerosis: Distinguishing Clinical and MRI Features, and more!

  • Network Functions and Plasticity

    Perspectives from Studying Neuronal Electrical Coupling in Microcircuits
    • 1 Edición
    • Jian Jing
    • Inglés
    Network Functions and Plasticity: Perspectives from Studying Neuronal Electrical Coupling in Microcircuits focuses on the specific roles of electrical coupling in tractable, well-defined circuits, highlighting current research that offers novel insights for electrical coupling‘s roles in sensory and motor functions, neural computations, decision-making, regulation of network activity, circuit development, and learning and memory. Bringing together a diverse group of international experts and their contributions using a variety of approaches to study different invertebrate and vertebrate model systems with a focus on the role of electrical coupling/gap junctions in microcircuits, this book presents a timely contribution for students and researchers alike.

  • Systems Factorial Technology

    A Theory Driven Methodology for the Identification of Perceptual and Cognitive Mechanisms
    • 1 Edición
    • Daniel Little + 3 más
    • Inglés
    Systems Factorial Technology: A Theory Driven Methodology for the Identification of Perceptual and Cognitive Mechanisms explores the theoretical and methodological tools used to investigate fundamental questions central to basic psychological and perceptual processes. Such processes include detection, identification, classification, recognition, and decision-making. This book collects the tools that allow researchers to deal with the pervasive model mimicry problems which exist in standard experimental and theoretical paradigms and includes novel applications to not only basic psychological questions, but also clinical diagnosis and links to neuroscience. Researchers can use this book to begin using the methodology behind SFT and to get an overview of current uses and future directions. The collected developments and applications of SFT allow us to peer inside the human mind and provide strong constraints on psychological theory.

  • Disease-Modifying Targets in Neurodegenerative Disorders

    Paving the Way for Disease-Modifying Therapies
    • 1 Edición
    • Veerle Baekelandt + 1 más
    • Inglés
    Disease-Modifying Targets in Neurodegenerative Disorders: Paving the Way for Disease-Modifying Therapies examines specific neurodegenerative disorders in comprehensive chapters written by experts in the respective fields. Each chapter contains a summary of the disease management field, subsequently elaborating on the molecular mechanisms and promising new targets for disease-modifying therapies. This overview is ideal for neuroscientists, biomedical researchers, medical doctors, and caregivers, not only providing readers with a summary of the way patients are treated today, but also offering a glance at the future of neurodegenerative disorder treatment.

  • Essentials of Neuroanesthesia

    • 1 Edición
    • Hemanshu Prabhakar
    • Inglés
    Essentials of Neuroanesthesia offers useful insights on the anesthetic management of neurosurgical and neurologic patients. This book covers all topics related to neuroanesthesia, providing essential knowledge on the brain and spinal cord. Sections include chapters on anatomy, physiology, and pharmacology, along with specific chapters related to various neurosurgical and neurological problems and their anesthetic management. This book provides an understanding of related issues, such as palliative care, evidence based practice of neuroanesthesia, sterilization techniques, biostatistics, and ethical issues, and is useful for trainees, clinicians, and researchers in the fields of neurosurgery, neurocritical care, neuroanesthesia, and neurology.

  • Adenosine Receptors in Neurodegenerative Diseases

    • 1 Edición
    • David Blum + 1 más
    • Inglés
    Adenosine Receptors in Neurodegenerative Diseases covers the role of adenosine receptors in brain function, also focusing on related methodologies and perspectives in therapeutics. The book provides an up-to-date overview by the best specialists in the field, helping readers consider the importance of adenosine and expand the global impact and visibility of adenosine research in the CNS field. Chapters include adenosine biology and signaling, gene regulation, control of motor function, and novel adenosine-based therapies in the CNS. It is an ideal resource for researchers, advanced graduate students, clinicians, and industry scientists working in the fields of clinical neuroscience and molecular and cellular neuroscience.

  • Music, Passion, and Cognitive Function

    • 1 Edición
    • Leonid Perlovsky
    • Inglés
    Music, Passion, and Cognitive Function examines contemporary cognitive theories of music, why they cannot explain music’s power over us, and the origin and evolution of music. The book presents experimental confirmations of the theory in psychological and neuroimaging research, discussing the parallel evolution of consciousness, musical styles, and cultures since Homer and King David. In addition, it explains that 'in much wisdom is much grief' due to cognitive dissonances created by language that splits the inner world. Music enables us to survive in this sea of grief, overcomes discomforts and stresses of acquiring new knowledge, and unifies the soul, hence the power of music.

  • Neural Data Science

    A Primer with MATLAB® and Python™
    • 1 Edición
    • Erik Lee Nylen + 1 más
    • Inglés
    A Primer with MATLAB® and Python™ present important information on the emergence of the use of Python, a more general purpose option to MATLAB, the preferred computation language for scientific computing and analysis in neuroscience. This book addresses the snake in the room by providing a beginner’s introduction to the principles of computation and data analysis in neuroscience, using both Python and MATLAB, giving readers the ability to transcend platform tribalism and enable coding versatility.

  • Hearing Loss

    Causes, Prevention, and Treatment
    • 1 Edición
    • Jos J. Eggermont
    • Inglés
    Hearing Loss: Causes, Prevention, and Treatment covers hearing loss, causes and prevention, treatments, and future directions in the field, also looking at the cognitive problems that can develop. To avoid the “silent epidemic” of hearing loss, it is necessary to promote early screening, use hearing protection, and change public attitudes toward noise. Successful treatments of hearing loss deal with restoring hearing sensitivity via hearing aids, including cochlear, brainstem, or midbrain implants. Both the technical aspects and effects on the quality of life of these devices are discussed. The integration of all aspects of hearing, hearing loss, prevention, and treatment make this a perfect one-volume course in audiology at the graduate student level. However, it is also a great reference for established audiologists, ear surgeons, neurologists, and pediatric and geriatric professionals.

  • Addictive Substances and Neurological Disease

    Alcohol, Tobacco, Caffeine, and Drugs of Abuse in Everyday Lifestyles
    • 1 Edición
    • Ronald Ross Watson + 1 más
    • Inglés
    Addictive Substances and Neurological Disease: Alcohol, Tobacco, Caffeine, and Drugs of Abuse in Everyday Lifestyles is a complete guide to the manifold effects of addictive substances on the brain, providing readers with the latest developing research on how these substances are implicated in neurological development and dysfunction. Cannabis, cocaine, and other illicit drugs can have substantial negative effects on the structure and functioning of the brain. However, other common habituating and addictive substances often used as part of an individual’s lifestyle, i.e., alcohol, tobacco, caffeine, painkillers can also compromise brain health and effect or accentuate neurological disease. This book provides broad coverage of the effects of addictive substances on the brain, beginning with an overview of how the substances lead to dysfunction before examining each substance in depth. It discusses the pathology of addiction, the structural damage resulting from abuse of various substances, and covers the neurobiological, neurodegenerative, behavioral, and cognitive implications of use across the lifespan, from prenatal exposure, to adolescence and old age. This book aids researchers seeking an understanding of the neurological changes that these substances induce, and is also extremely useful for those seeking potential treatments and therapies for individuals suffering from chronic abuse of these substances.

  • Stress and Epigenetics in Suicide

    • 1 Edición
    • Vsevolod Rozanov
    • Inglés
    Stress and Epigenetics in Suicidediscusses the central role of epigenetic modifications in suicidal behavior. As early-life stress and an individual's ability to cope with such stressors, combined with psychological factors, social factors, and existential and cognitive factors can predispose young people to suicidal behavior and put them at added risk of suicidal behavior later in life, this book provides readers with an overview of the neurobiology of stress, an introduction to the epigenetic changes induced by stress, and an understanding of how vulnerability and resilience to stress are built. It integrates these mechanisms into a biobehavioral model of suicide based on epigenetic marks, gene-environment interactions, and other stressors. More importantly, it provides future direction for research and discusses potential interventions. This book is an ideal and trusted resource for researchers and clinicians who are interested in learning how the environment can affect behavior through genetics, and for those seeking the development of new methods for suicide prevention.

  • Primer on Cerebrovascular Diseases

    • 2 Edición
    • Louis R. Caplan + 6 más
    • Inglés
    Primer on Cerebrovascular Diseases, Second Edition, is a handy reference source for scientists, students, and physicians needing reliable, up-to-date information on basic mechanisms, physiology, pathophysiology, and medical issues related to brain vasculature. The book consists of short, specific chapters written by international experts on cerebral vasculature, presenting the information in a comprehensive and easily accessible manner. Numerous changes have occurred in the field since the publication of the first edition in 1997, particularly our understanding of the genetic aspects of cerebrovascular disease. This updated edition reflects the advances made over the last two decades, not only demonstrating the promise for therapy, but also for a molecular understanding of cerebrovascular diseases. The new edition includes new and expanded topics, including carotid stenting, Iatrogenic causes of stroke, axonal transport and injury, RNAIs, proteomics, and more. 2018 BMA Medical Book Awards Highly Commended in Neurology.

  • The Human Sciences after the Decade of the Brain

    • 1 Edición
    • Jon Leefmann + 1 más
    • Inglés
    The Human Sciences after the Decade of the Brain brings together exciting new works that address today’s key challenges for a mutual interaction between cognitive neuroscience and the social sciences and humanities. Taking up the methodological and conceptual problems of choosing a neuroscience approach to disciplines such as philosophy, history, ethics and education, the book deepens discussions on a range of epistemological, historical, and sociological questions about the "neuro-turn" in the new millennium. The book’s three sections focus on (i) epistemological questions posed by neurobiologically informed approaches to philosophy and history, (ii) neuroscience’s influence on explanations for social and moral behavior, and (iii) the consequences of the neuro-turn in diverse sectors of social life such as science, education, film, and human self-understanding. This book is an important resource both for students and scholars of cognitive neuroscience and biological psychology interested in the philosophical, ethical, and societal influences of—and on—their work as well as for students and scholars from the social sciences and humanities interested in neuroscience.

  • Translational Immunotherapy of Brain Tumors

    • 1 Edición
    • John H. Sampson
    • Inglés
    Translational Immunotherapy of Brain Tumors gives researchers and practitioners an up-to-date and comprehensive overview of the field. Chapters include adoptive immunotherapy, immunosuppression, CAR therapy of brain tumors, and dendritic cell therapy for brain tumors. Very few agents have been shown to be efficacious in the treatment of malignant gliomas. Recently, there have been a number of studies demonstrating the potential success of immunotherapy for brain tumors. Immunotherapeutics are becoming the most frequent drugs to be used in cancer therapy. These new breakthroughs, now approved by the FDA, are a part of multiple phase III international trials and ongoing research in malignant glioma, meaning that the information in this cutting-edge book will be of great importance to practitioners and researchers alike. 2018 BMA Medical Book Awards Highly Commended in Oncology

  • Mathematics for Neuroscientists

    • 2 Edición
    • Fabrizio Gabbiani + 1 más
    • Inglés
    Mathematics for Neuroscientists, Second Edition, presents a comprehensive introduction to mathematical and computational methods used in neuroscience to describe and model neural components of the brain from ion channels to single neurons, neural networks and their relation to behavior. The book contains more than 200 figures generated using Matlab code available to the student and scholar. Mathematical concepts are introduced hand in hand with neuroscience, emphasizing the connection between experimental results and theory.

  • Critical Care Neurology Part I

    Neurocritical Care
    • 1 Edición
    • Volumen 140
    • Inglés
    Critical Care Neurology, Part I: Neurocritical Care focuses on the care specialists and general neurologists that consult in the ICU and their work with patients in acute, life-threatening situations who are dealing with neurologic or neurosurgical crises emanating from either a preexisting neurologic syndrome or from a new neurologic complication appearing as a result of another medical or surgical critical illness. These two separate clinical situations form the pillars of neurocritical care, hence these practices are addressed via two separate, but closely related, HCN volumes. Chapters in both focus on pathophysiology and management, and are tailored for both general neurologists and active neurocritical specialists, with a specific focus on management over diagnostics. Part I addresses the principles of neurocritical care and the management of various neurologic diseases. Part II addresses the interplay between neurologic complications and the surgical, medical, cardiac, and trauma of critical illnesses that most typically present in the ICU.

  • Critical Care Neurology Part II

    Neurology of Critical Illness
    • 1 Edición
    • Volumen 141
    • Inglés
    Critical Care Neurology, Part II: Neurology of Critical Illness focuses on the care specialists and general neurologists that consult in the ICU and their work with patients in acute, life-threatening situations who are dealing with neurologic or neurosurgical crises emanating from either a preexisting neurologic syndrome or from a new neurologic complication appearing as a result of another medical or surgical critical illness. These two separate clinical situations form the pillars of neurocritical care, hence these practices are addressed via two separate, but closely related, HCN volumes. Chapters in both focus on pathophysiology and management, and are tailored for both general neurologists and active neurocritical specialists, with a specific focus on management over diagnostics. Part I addresses the principles of neurocritical care and the management of various neurologic diseases. Part II addresses the interplay between neurologic complications and the surgical, medical, cardiac, and trauma of critical illnesses that most typically present in the ICU.

  • Sleep and Neurologic Disease

    • 1 Edición
    • Mitchell G. Miglis
    • Inglés
    Sleep and Neurologic Disease reviews how common neurologic illnesses, such as Parkinson’s Disease and Alzheimer’s dementia impact sleep. In addition, the book discusses how common primary sleep disorders influence neurologic diseases, such as the relationship between obstructive sleep apnea and stroke, as well as their association with various primary headache disorders and epilepsy syndromes. The utilization of sleep technology, such as polysomnography, multiple sleep latency testing, actigraphy, laboratory and CSF testing is also covered. The book is written for the practicing neurologist, sleep physician, neuroscientist, and epidemiologist studying sleep.

  • Innovative Neuromodulation

    • 1 Edición
    • Jeffrey Arle + 1 más
    • Inglés
    Innovative Neuromodulation serves as an extensive reference that includes a basic introduction to the relevant aspects of clinical neuromodulation that is followed by an in-depth discussion of the innovative surgical and therapeutic applications that currently exist or are in development. This information is critical for neurosurgeons, neurophysiologists, bioengineers, and other proceduralists, providing a clear presentation of the frontiers of this exciting and medically important area of physiology. As neuromodulation remains an exciting and rapidly advancing field—appealing to many disciplines—the editors’ initial work (Essential Neuromodulation, 2011) is well complemented by this companion volume.

  • Molecular and Cellular Therapies for Motor Neuron Diseases

    • 1 Edición
    • Nicholas M Boulis + 2 más
    • Inglés
    Molecular and Cellular Therapies for Motor Neuron Diseases discusses the basics of the diseases, also covering advances in research and clinical trials. The book provides a resource for students that will help them learn the basics in a detailed manner that is required for scientists and clinicians. Users will find a comprehensive overview of the background of Amyotrophic Lateral Sclerosis (ALS/Lou Gehrig’s Disease) and Spinal Muscular Atrophy (SMA), along with the current understanding of their genetics and mechanisms. In addition, the book details gene and cell therapies that have been developed and their translation to clinical trials.

  • Neurocritical Care Management of the Neurosurgical Patient

    • 1 Edición
    • Monisha Kumar + 3 más
    • Inglés
    Kumar and colleagues’ Neurocritical Care Management of the Neurosurgical Patient provides the reader with thorough coverage of neuroanatomical structures, operative surgical approaches, anesthetic considerations, as well as the full range of known complications relating to elective and non-elective neurosurgical procedures. Drawing upon the expertise of an interdisciplinary team of physicians from neurosurgery, neurology, anesthesiology, critical care, and nursing backgrounds, the text covers all aspects intensivists need to be aware of in order to provide optimal patient care.

  • The Pituitary

    • 4 Edición
    • Shlomo Melmed
    • Inglés
    The Pituitary, Fourth Edition, continues the tradition of a cogent blend of basic science and clinical medicine which has been the successful hallmark of prior editions. This comprehensive text is devoted to the pathogenesis, diagnosis, and treatment of pituitary disorders. The new edition has been extensively revised to reflect new knowledge derived from advances in molecular and cell biology, biochemistry, diagnostics, and therapeutics as they apply to the pituitary gland. The wide spectrum of clinical disorders emanating from dysfunction of the master gland is described in detail by experts in the field. Fundamental mechanisms underlying disease pathogenesis are presented to provide the reader with an in-depth understanding of mechanisms subserving both normal and disordered pituitary hormone secretion and action. This extensive body of knowledge is useful for students, trainees, physicians, and scientists who need to understand critical pituitary functions and how to care for patients with pituitary disorders. Chapters provide medical students, clinical and basic endocrinology trainees, endocrinologists, internists, pediatricians, gynecologists, and neurosurgeons with a comprehensive, yet integrated, text devoted to the science and art of pituitary medicine.

  • DNA Modifications in the Brain

    Neuroepigenetic Regulation of Gene Expression
    • 1 Edición
    • Timothy W Bredy
    • Inglés
    DNA Modifications in the Brain: Neuroepigenetic Regulation of Gene Expression begins with an historical overview of the early discoveries surrounding DNA methylation in the mammalian brain and then explores the evidence supporting a role for this epigenetic mechanism in controlling gene expression programs across the lifespan in both normal and diseased states. Chapters describe new directions and technological advances, and provide an overview of what the future holds for this exciting new field. This book is ideal for medical, graduate and advanced undergraduate students, but is also a great resource for researchers who need a broad introduction to the dynamic nature of DNA that sheds light on evolving concepts of gene-environment interaction and their effects on adaptation and neuropsychiatric disease.

  • Nutrition and Lifestyle in Neurological Autoimmune Diseases

    Multiple Sclerosis
    • 1 Edición
    • Ronald Ross Watson + 1 más
    • Inglés
    Nutrition and Lifestyle in Neurological Autoimmune Diseases: Multiple Sclerosis discusses important discoveries relating to the types of, and efficacy of, nutritional and lifestyle responses to symptoms and reoccurrence of MS. Each chapter defines a new approach to use in foods, dietary supplements, exercise, behavior, and/or lifestyle in health promotion and symptoms management for MS. This book presents the role of non-pharmaceutical approaches and is essential reading for neurologists, physicians, nurses, nutritionists, dietitians, healthcare professionals, research scientists, biochemists, and general practitioners.

  • Pediatric Brain Tumors Update, An Issue of Neuroimaging Clinics of North America

    • 1 Edición
    • Volumen 27-1
    • Lara A. Brandão
    • Inglés
    This issue of Neuroimaging Clinics of North America focuses on Pediatric Brain Tumors, and is edited by Dr. Lara A. Brandão. Articles will include: Posterior fossa tumors in pediatric patients; Supratentorial tumors in pediatric patients; Brain tumors in the neonate; Pineal region masses in pediatric patients; Sellar and suprasellar tumors in pediatric patients; Extraparenchymal lesions in pediatric patients; Tumor and tumor-like masses in pediatric patients that involve multiple spaces; Neuroimaging of innovative peptide base vaccine therapy in pediatric brain tumors; Advanced MRI in pediatric brain tumors: clinical applications; and much more!

  • Neuro-Ophthalmology, An Issue of Neurologic Clinics

    • 1 Edición
    • Volumen 35-1
    • Andrew G. Lee
    • Inglés
    This issue of Neurologic Clinics, edited by Dr. Andrew Lee, will focus on Neuro-Ophthalmology. The topics covered in the issue include, but are not limited to new treatments for nonarteritic anterior ischemic optic neuropathy; idiopathic intracranial hypertension; neuroimaging for the Horner Syndrome; OCT; erectile dysfunction agents and NAION; NMO; ocular myasthenia gravis; imaging for third nerve palsy; treatment of central retinal artery occlusion; and orbital disease, among others.

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