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Elsevier

Libros en Neurociencia

  • The Rat Brain in Stereotaxic Coordinates

    • 7 Edición
    • George Paxinos + 1 más
    • Inglés
    Since its first edition in 1982, the Paxinos and Watson rat brain atlas has become the most trusted source of accurate coordinates and anatomical information in laboratories throughout the world. It has been cited over 60,000 times, making it the most cited publication in neuroscience. The seventh edition incorporates new findings on developmental gene expression and presents the boundaries of neuromeres in sagittal sections.

  • A Neurological Study of Newborn Infants

    Clinics in Developmental Medicine, No. 28
    • 1 Edición
    • David J. Beintema
    • Inglés
    A Neurological Study of Newborn Infants considers the consistencies and inconsistencies of neonatal neurological signs. The possibility of a relationship between pre- and perinatal complications of pregnancy and later cerebral dysfunction has led to an increasing interest in the early detection of these defects in the newborn infant. This book is divided into nine chapters, and begins with a presentation of standardized procedures to obtain reliable information from the neurological examination. The next chapters deal with the developmental course of neurological signs during the first days of life. The final chapters discuss the potential effects of obstetrical and postnatal conditions on the developmental course and the consistency of neurological signs throughout the neonatal period. This book is an invaluable source for developmental biologists, neurologists, pediatricians, and obstetricians.

  • Cerebral Palsy

    A Clinical and Neuropathological Study
    • 1 Edición
    • Erna Christensen + 1 más
    • Inglés
    Cerebral Palsy: A Clinical and Neuropathological Study is an account of a detailed study in which obstetrical, neonatal and neurological investigations on a large group of patients are presented with full neuropathological data found at subsequent necropsy. The book discusses the general autopsy findings and neuropathological techniques; as well as neuropathological findings in the different clinical entities. The text also describes the neuropathological findings and classification; progressive encephalopathies; and epilepsy. Neurologists will find the book invaluable.

  • Excitation and Inhibition

    Synaptic Morphology
    • 1 Edición
    • Koji Uchizono
    • Inglés
    Excitation and Inhibition: Synaptic Morphology proposes the S-F hypothesis that emphasizes the relationship between structure and function of synapses. This book begins with an introduction to the notion of inhibition in the physiology of the nervous system and history of “synapse”, followed by a discussion on the development of concept and morphological correlates of excitation and inhibition in relation to the S-F hypothesis. The mechanism of synaptic excitation and inhibition, physiological classification of neurons, and release mechanism of transmitters are also elaborated. This text describes the synaptic vesicles as a basis of transmitter, membrane recycle, transmission in the sympathetic ganglion, and transmitter substance. The criticism of S-F hypothesis, which deliberates the skeptical investigations of specialists regarding the simplicity and immaturity of the S-F hypothesis of synaptic morphology are provided at the end. This publication is beneficial to medical students and practitioners aiming to acquire knowledge of the physiology of synapses.

  • The Study of Behavioral Development

    • 1 Edición
    • Joachim F. Wohlwill
    • David S. Palermo
    • Inglés
    The Child Psychology Series: The Study of Behavioral Development concerns the formulation of general laws of development, transcending the realm of the development of the individual from infancy to maturity. This book provides a systematic treatment of problems of research design, strategy, and data analysis that relate specifically to the study of developmental changes in behavior. The topics discussed include developmental psychology in the 1970s, age variable in psychological research, and programmatic view of the task of developmental psychology. The problems of measurement and quantification in developmental psychology, correlational methods in the study of developmental change, and experimental manipulation of developmental change are also elaborated. This publication is recommended for psychologists, specialists, and students learning the nature of behavioral change.

  • Textbook of Neuropathology

    • 2 Edición
    • Arthur Weil
    • Inglés
    Textbook of Neuropathology, Second Edition covers some of the significant advances in understanding the theoretical and experimental aspects of neuropathology. Neuropathology is the study of the nervous tissue in disease and the determination of deviations of its structures from the normal. This edition is composed of 13 chapters, and begins with the description of the chemical changes occurring in the cell through autolysis and fixation. The subsequent chapters are devoted to studies on better understanding of the vitamin deficiencies, the discovery of the sulfonamides and their contribution to the therapy of meningitis, and the different forms of shock treatment applied to selected cases of neurosis and psychosis. The remaining chapters explore the contribution of neuropathological investigation in various medical conditions, including anemic softening, arteriosclerosis, inflammation, infections, intoxications, injuries, degenerative diseases, tumors, and congenital malformations. This book will be of use to neuropathologists and workers and researchers in the allied fields.

  • The Physiology of Synapses

    • 1 Edición
    • John Carew Eccles
    • Inglés
    The Physiology of Synapses covers the considerable advances in understanding the complex physiology of synapses. This book is divided into 16 chapters that emphasize the mechanism of synaptic transmission. The first chapters describe the structural and physiological features of chemically transmitting synapses. The subsequent chapters deal with the excitatory postsynaptic responses to presynaptic impulse and the release of transmitter by presynaptic impulses. These topics are followed by discussions of the impulse generation by the excitatory postsynaptic potential; the postsynaptic electrical events produced by chemically transmitting inhibitory synapses; the ionic mechanism generating the inhibitory postsynaptic potential. The last chapters consider the mechanism of inhibitory transmitter substances, pathways responsible for postsynaptic inhibitory action, and the trophic and plastic properties of synapses. This book will prove useful to physiologists, neurologists, and researchers.

  • Receptors

    Model Systems and Specific Receptors
    • 1 Edición
    • P. Michael Conn
    • Inglés
    Methods in Neurosciences, Volume 11: Receptors: Model Systems and Specific Receptors is a compilation of papers that describes techniques and information that are important to the neurosciences. This volume discusses preferred receptor techniques, molecular techniques, and methods to determine receptor subclasses and localization in the ligand design. The first paper discusses the steroid receptor found in the central nervous system for steroid hormones that affects strongly the structure and function of both developed and immature nervous systems. Another paper describes how a glycoprotein of 79.5 kDa (transferrin) carries iron in the blood stream for delivery to different tissues, after the transferrin has bound with a specific receptor on the surface of the cell. This book also explains the binding sites of pituitary adenylate cyclase-activating polypeptide in the human brain, while one paper analyzes the neurotensin receptors during the primary culture of neurons. This volume then also analyzes the structure and function of the fast nerve growth factor receptor, particularly how a signal on the outside of a cell is transmitted to the cell's interior. This collection is helpful for microbiologists, cellular researchers, students, and professors in the discipline of neurosciences.

  • Neuropeptide Technology

    Synthesis, Assay, Purification, and Processing
    • 1 Edición
    • P. Michael Conn
    • Inglés
    Methods in Neurosciences, Volume 6: Neuropeptide Technology: Synthesis, Assay, Purification, and Processing describes procedures and tools of assay useful for the identification, purification, and quantification of neuropeptides and their receptors. This volume is divided into four sections— chemical synthesis and biosynthesis; measurement of neuropeptides; purification and characterization; and neuropeptide degrading and processing enzymes. In these sections, this book specifically discusses the synthesis of peptide substrates for protein kinase C; synthesis of glycosyl neuropeptides; and ultrastructural localization of peptides. The measurement of neurokinin B by radioimmunoassay; purification and characterization of neuroendocrine peptides from rat brain; and preparation of glia maturation factor ß are also elaborated. This text likewise covers the assays for arginine/lysine carboxypeptidases and enzymes that metabolize atrial natriuretic peptide. This publication is beneficial to neuroscientists and students researching on the synthesis, assay, purification, and processing of neuropeptides.

  • Progress in Behavior Modification

    Volume 6
    • 1 Edición
    • Michel Hersen + 2 más
    • Inglés
    Progress in Behavior Modification, Volume 6, is a multidisciplinary serial publication that encompasses the contributions of psychology, psychiatry, social work, speech therapy, education, and rehabilitation. This serial aims to meet the need for a review publication that undertakes to present yearly in-depth evaluations that include a scholarly examination of theoretical underpinnings, a careful survey of research findings, and a comparative analysis of existing techniques and methodologies. The discussions center on a wide spectrum of child and adult disorders. The book opens with a chapter on the various behavioral procedures for treating insomnia. This is followed by separate chapters on behavioral analysis and formulation of the problem of stuttering; the assessment and treatment of enuresis and encopresis in children; and the development of behavior modification in Latin America. Subsequent chapters deal with the analysis of behavior modification from the point of view of its social identity; the conceptual and clinical literature resulting from the broader emphasis in behavior modification; and the relationship between therapist and client.

  • Models of Human Memory

    • 1 Edición
    • Donald A. Norman
    • Inglés
    Models of Human Memory provides an overview of the state of knowledge on human memory models. The book begins with an introductory chapter on the basic stages of the memory system and the historical roots of memory models. The remaining chapters are organized into five parts. Part I on memory systems covers topics such as a system for perception and memory; multi-trace strength theory of memory; and a model for postperceptual verbal memory that postulates a single memory store, with multiple copies, called replicas, created in memory by rehearsal processes. Part II presents studies phoneme storage and word recognition. Part III on memory for associations examines the storage-retrieval theory for the memorizing processes and presents simple model of short-term memory (STM) for paired associates. Part IV on storage and retrieval mechanisms deals with mechanisms of repetition and rehearsal in short-term memory; models of recall and recognition; and memory search models. Part V presents a theory of human long-term associative memory; and examines conceptual and methodological interactions between information-processi... investigations of cognitive activity and attempts to build models of memory.

  • Progress in Behavior Modification

    Volume 4
    • 1 Edición
    • Michel Hersen + 2 más
    • Inglés
    Progress in Behavior Modification, Volume 4, is a multidisciplinary serial publication that encompasses the contributions of psychology, psychiatry, social work, speech therapy, education, and rehabilitation. This serial aims to meet the need for a review publication that undertakes to present yearly in-depth evaluations that include a scholarly examination of theoretical underpinnings, a careful survey of research findings, and a comparative analysis of existing techniques and methodologies. The discussions center on a wide spectrum of child and adult disorders. The present volume opens with a chapter on behavioral treatment for obesity. This is followed by separate chapters on applications of reinforcement techniques in the areas of pollution control and energy conservation, job performance and unemployment, community self-government, racial integration, and others; and behavior modification in community settings. Subsequent chapters deal with demand characteristics in behavior modification; the clinical utility of biofeedback procedures; and the technology of training parents in behavior therapy. The final chapter reviews the rationale and empirical support for the extinction approach of implosive (flooding) therapy.

  • Brain Receptor Methodologies

    Amino Acids. Peptides. Psychoactive Drugs
    • 1 Edición
    • Paul J. Marangos + 2 más
    • Inglés
    Brain Receptor Methodologies: Part B Amino Acids. Peptides. Psychoactive Drugs is the second of the two-part first volume of the Neurobiological Research series, which provides a comprehensive view of various subdisciplines within neurobiology. The first volume (Parts A and B) deals with the area of neurotransmitter and neuromodulator receptors in brain; future volumes will cover the subdisciplines of neuroanatomy, neurophysiology, brain-specific macromolecules, neurochemistry, and behavioral neurobiology. It is hoped that the series will be of equal value for both basic as well as clinical scientists Part B continues from Part A with the remainder of Section II, specific receptor binding methodologies. Subsection II,B deals with receptors for amino acids and neuropeptides and covers areas including GABA, glycine, carnosine, opiates, bombesin, CCK, TRH, and substance P. Amino acids probably represent the majority of brain neurotransmitter substances, at least relative to the amines and acetylcholine, although with the exception of GABA, the amino acids remain relatively uncharacterized in brain. Their further study should receive high priority.

  • Comparative Neuropathology

    • 1 Edición
    • J. R. M. Innes + 1 más
    • Inglés
    Comparative Neuropathology focuses on documented accounts of neurologic diseases and congenital defects in animals. The book first offers information on neuropathology, neuroanatomy, and cerebrospinal fluid (CSF). The domesticated animals that have CSF include horses, dogs, pigs, cats, rabbits, and cattle. The text then elaborates on neurologic diseases of apes and monkeys. Discussions focus on confluent leucoencephalosis and perivascular myelosis, encephalopathies and dysenteric syndromes, meningitis, epilepsies, tuberculosis, cerebellar atrophy and experimental manganese poisoning, and choreic syndrome in baboons with corticostriate encephalitis. The publication examines the diseases of the skeletal muscle and hypophysis, including general reactions of muscles to injuries, congenital defects, muscular dystrophies, changes in muscle associated with specific diseases, and tumor. The manuscript also takes a look at inherited diseases and congenital anomalies, protozoan and bacterial infections, and demyelinating or myelinoclastic diseases. The text is a dependable reference for readers interested in comparative neuropathology.

  • Progress in Behavior Modification

    Volume 5
    • 1 Edición
    • Michel Hersen + 2 más
    • Inglés
    Progress in Behavior Modification, Volume 5, is a multidisciplinary serial publication that encompasses the contributions of psychology, psychiatry, social work, speech therapy, education, and rehabilitation. This serial aims to meet the need for a review publication that undertakes to present yearly in-depth evaluations that include a scholarly examination of theoretical underpinnings, a careful survey of research findings, and a comparative analysis of existing techniques and methodologies. The discussions center on a wide spectrum of child and adult disorders. The book opens with a chapter on the assessment and treatment of minimal dating behavior in college students. This is followed by separate chapters on methods of behavioral control of excessive drinking; behavioral analysis and treatment of child noncompliance to parental requests; and behavioral group therapy. Subsequent chapters deal with the conceptual underpinnings of research in children's self-management and treatment strategies; the assessment and therapeutic functions of self-monitoring; and behavioral treatment in homosexuality.

  • Methods in Neurosciences

    Electrophysiology and Microinjection
    • 1 Edición
    • P. Michael Conn
    • Inglés
    Methods in Neurosciences, Volume 4: Electrophysiology and Microinjection is a collection of papers that deals with the electrically excitability feature of many cell types. This volume describes the characteristic features of some nervous tissue to conduct signals along cellular paths or ""wires."" The text presents such paths as a way stimuli are transferred in the nervous system. Section I reviews the recording methodologies such as those used in measuring noninactivating calcium current in smooth muscles cells or the two-suction electrode voltage-clamp recording. Section II deals in detail with voltage clamping and voltammetry; the text also explains the practical steps in using the current pump-assisted voltage clamp. One paper examines the X-ray microprobe analysis of voltage clamped single heart ventricular myocytes, while another paper explains in vivo voltammetry. Section III addresses electrophysiology and purification of specific receptors; one paper presents the results of an electrophysiological study of hormone secretion by single adenohypophyseal cells. Section IV describes special electrodes and equipment, while Section V deals with special preparations needed in culture preparation or in the study of pharmacology of excitatory amino acids on neurons found in the central nervous system. Chapter VI addresses data analysis and reduction such as digital filtering of bioelectric potentials in personal computers. This book will prove valuable for microbiologists, cellular scientists, microchemists, and academicians working in the fields of neuroscience.

  • Principles, Practices, and Positions in Neuropsychiatric Research

    Proceedings of a Conference Held in June 1970 at the Walter Reed Army Institute of Research, Washington, D.C., in Tribute to Dr. David Mckenzie Rioch upon His Retirement as Director of the Neuropsychiatry Division of That Institute
    • 1 Edición
    • Joseph V. Brady + 1 más
    • Inglés
    Principles, Practices and Positions in Neuropsychiatric Research contains the proceedings of a conference held in June 1970 at the Walter Reed Army Institute of Research, Washington, D.C., in tribute to Dr. David McKenzie Rioch upon his retirement as Director of the Neuropsychiatry Division of that institute. This book is composed of the original contributions presented at the conference, as well as several invited papers that could not be programmed at the meeting because of certain limitations. Topics covered in some papers focus on anatomy of the thalamus; glia-neuronal interaction; receptor characteristics and conduction velocities in bladder afferents; responses of photoreceptors; and specificity of responses of cells in the visual cortex. This text also discusses the channeling of responses elicited by hypothalamic stimulation; neurochemistry of reward and punishment; behavioral analysis of aphasia; and biology of sleep. The military psychiatry and changing systems of mental health care, as well as psychological issues in training for research in psychiatry are also addressed. The contributions in this book will serve to reflect the remarkable range of bio-social research interest and competence.

  • Neurobiology and Behavior

    • 1 Edición
    • A. O. Dennis Willows
    • Inglés
    The Mollusca, Volume 8: Neurobiology and Behavior, Part 2, provides an overview of the state of knowledge in molluscan neurobiology and behavior. It is part of a multivolume treatise that covers the areas of structure and function, metabolic biochemistry, molecular biomechanics, environmental biochemistry, physiology, ecology, reproduction and development, neurobiology and behavior, and evolution. The Mollusca is intended to serve a range of disciplines—zoology, biochemistry, physiology, and paleontology. It will prove useful to researchers and to all others with interests in mollusks. The book contains four chapters and begins with a discussion of neural control of cephalopod behavior. Subsequent chapters deal with the neuroanatomy of selected gastropod species; molluscan membranes, gates, and channels; and molluscan transmitters and modulators.

  • Applied Neurophysiology

    With Particular Reference to Anaesthesia
    • 1 Edición
    • J.A. Simpson + 1 más
    • Inglés
    Applied Neurophysiology is intended to promote understanding of the structure and function of the human nervous system for anesthetists. For that reason this book presented concepts rather than critical discussions of experimental work. This book is organized into five parts. There are chapters intended for specialists such as those on vision, control of gaze, hearing and locomotion that were included in order to introduce concepts on brain stem automatisms and cortical function necessary to understand respiration and conscious awareness. There is also a chapter on autonomic nervous system which provides an account of the regulation of the cerebral circulation. The final sections of this volume also include quantitative data and references to original studies which were not thought necessary in other sections. This book will be of interest to anesthetists, clinicians, psychologists, speech pathologists and even neurologists in training.

  • Neurobiology and Behavior

    • 1 Edición
    • A. O. Dennis Willows
    • Inglés
    The Mollusca, Volume 8: Neurobiology and Behavior, Part 1, provides an overview of the state of knowledge in molluscan neurobiology and behavior. It is part of a multivolume treatise that covers the areas of structure and function, metabolic biochemistry, molecular biomechanics, environmental biochemistry, physiology, ecology, reproduction and development, neurobiology and behavior, and evolution. The Mollusca is intended to serve a range of disciplines—zoology, biochemistry, physiology, and paleontology. It will prove useful to researchers and to all others with interests in molluscs. The book contains four chapters and begins with a chapter on the behavior of gastropod mollusks. Subsequent chapters deal with learning in gastropod mollusks, the neuronal control of behavior in gastropods, and the development and plasticity of molluscan neurons.

  • Biochemical Factors Concerned in the Functional Activity of the Nervous System

    First International Meeting of the International Society for Neurochemistry, Strasbourg, 1967
    • 1 Edición
    • D. Richter
    • Inglés
    Biochemical Factors Concerned in the Functional Activity of the Nervous System presents the biological aspects concerned in the functional activity of the nervous system. This book covers several interesting topics concerning the central nervous system, including phospholipids, RNA synthesis, nerve impulse flow, and nerve growth factor. Comprised of 213 chapters, this book begins with an overview of the electron micrographs of calcium–ATP–phosphol... complexes. This text then examines the biochemical and histochemical studies on sectioned rat spinal cords, which demonstrated two types of monoamine-reducing drugs. Other chapters consider the diversity of antagonistic relations between the thiamine derivatives and vitamin B6, which is manifested by changes in the glutamate–GABA, histidine–histamine, tryptophan–serotonin... and tyrosine–noradrenali... systems. This book discusses as well the influence of a conditioned avoidance training experience on the incorporation of radioactive uridine into the RNA of mouse brain. The final chapter deals with the amino acid-incorporating activity of cerebral polyribosomes. This book is a valuable resource for biochemists, neurologists, pharmacologists, and biophysicists.

  • Agrammatism

    • 1 Edición
    • Mary-Louise Kean
    • Inglés
    Agrammatism provides an overview of the state of knowledge on agrammatism, typically defined as a disorder of sentence production involving the selective omission of function words and some grammatical endings on words. The book opens with discussions of the diversity of the disorder. This is followed by separate chapters that address primarily questions of syntactic structure in agrammatism, from both linguistic and psycholinguistic perspectives. Within these two gross sections there is no consensus among the conclusions reached by the various authors. However, the position is taken that agrammatism is a disorder distinct from other aphasie disorders of sentence structure. This position is reconsidered in the final two chapters. Because of the intrinsically interdisciplinary character of research on agrammatism, it is hoped that the work presented in this volume will be of interest to linguists and psycholinguists working in areas outside the domain of aphasia, as well as to neurolinguists and neuropsychologists who are already involved in the study of language deficits.

  • Neurotrauma

    Treatment, Rehabilitation, and Related Issues
    • 1 Edición
    • Michael E. Miner + 1 más
    • Inglés
    Neurotrauma features the papers presented at the Second Houston Conference on Neurotrauma in Texas held in May 1985. These papers cover discussions on patients who have both brain and spinal cord injuries and acute care treatment and investigations of brain injury, as well as rehabilitation strategies and approaches. This second edition is organized into four parts. The first part deals with the treatment of less-than-severe head injury, barbiturate-induced coma, closed head injuries, and severely brain-injured patients. The second part focuses on the evaluation of physiological and anatomical recovery of brain injury patients, while the third part discusses the management of patients with combined head and spinal cord injury. The final part focuses on rehabilitation issues that include nonpharmacological management, the impact of traumatic brain injury on sexuality, and ethical aspects of lifesaving therapeutic strategies. This book may be of interest to persons dealing with studies on the treatment of brain and spinal cord injuries.

  • Variation in Chemical Composition of the Nervous System

    As Determined by Developmental and Genetic Factors
    • 1 Edición
    • G. B. Ansell
    • Inglés
    Variation in Chemical Composition of the Nervous System: As Determined by Developmental and Genetic Factors documents the proceedings of the International Neurochemical Conference held in Oxford, 1965. The three years since the last neurochemical meeting have witnessed rapid progress in the whole field of biology, including the development of new concepts based on fresh experimental data and new technical tools. A great deal of concentrated effort have led to advances in the molecular aspects of biological processes ,which have perhaps had most to offer to the formation of new concepts of primary cellular events, especially the genetic mechanism, regulatory cell processes, and protein production. This volume contains 100 chapters that provide an overview of the state of knowledge on the genetic and developmental aspects of the central nervous system. Topics covered include the activity of a plasma logenase in the brain of the developing rat; genetic selection of rats differing in brain biochemistry; the effects of thyroid hormones on steroid deposition in developing chick brain; and developmental changes in the gamma globulins of bovine cerebrospinal fluid.

  • Neuro-Ophthalmology

    • 1 Edición
    • R. Lindsay Rea
    • Inglés
    Neuro-Ophthalmology provides information pertinent to the neuro-ophthalmologic... examination of the eye. This book discusses the anatomy and function of the eye as well as its various diseases. Organized into 17 chapters, this book begins with an overview of the various equipment and methods used in the examination of the eye, including the Snellen's test type, a 13 dioptre lens, and electric ophthalmoscope. This text then discusses the principal reactions of the normal pupil, including the direct light reflex, reflex to accommodation, the spino-pupillary reflex, the psychical reflex, the orbicularis reflex, and the oculo-sensory reflex. Other chapters consider the anatomy of the muscles and nerves of the eye as well as it adnexa. This book discusses as well the condition of optic atrophy and its various types. The final chapter deals with the distinction between headache and neuralgia. This book is a valuable resource for ophthalmic surgeons and ophthalmologists.

  • Aspects of Neural Ontogeny

    • 1 Edición
    • A. F. W. Hughes
    • Inglés
    Aspects of Neural Ontogeny focuses on the interaction between the nervous system and peripheral organs during development, including history and development of neurons and the functions of nerves and muscles. The book first offers information on the development of neurons, including formation and growth of nerve fibers; growth cone and the extension of nerve fibers; history of the neuron theory; and path of nerve fibers. The manuscript then elaborates on the innervation of the tetrapod limb and the center and periphery. Discussions focus on the relationships between the ventral horn and muscles of the limb; experimental studies on limb plexus and limb nerves; and relationships between spinal nerves and limb muscles. The publication takes a look at the ontogeny of behavior, as well as pattern of motility, spontaneous movements, tetrapod limb, and experimental studies. The book is a dependable reference for readers interested in neural ontogeny.

  • The Neostriatum

    Proceedings of a Workshop Sponsored by the European Brain and Behaviour Society, Denmark, 17-19 April 1978
    • 1 Edición
    • Ivan Divac + 1 más
    • Inglés
    The Neostriatum presents the puzzles of the neostriatum from many different angles. This book presents significant findings concerning the structure and neurotransmitters of the neostriatum. Organized into four parts encompassing 20 chapters, this book begins with an overview of the basic organization of the neostriatum. This text then illustrates an impressive complexity of extrinsic and intrinsic neostriatum circuitry. Other chapters consider the view that the nervous system evolved as a hierarchy, so that non-cortical structures such as the corpus striatum retain their structure and function even when the latter is made subservient to more developed mechanisms of the cerebral cortex. This book discusses as well the behavioral roles of the neostriatum and reviews the behavioral data obtained with each of the major treatment and recording techniques. The final chapter deals with the important features of striatal functions. This book is a valuable resource for neuropsychopharmacol... neuropsychologists, neurophysiologists, psychologists, and scientists.

  • Atlas of the Prenatal Mouse Brain

    • 1 Edición
    • Uta B. Schambra + 1 más
    • Inglés
    The Atlas of the Prenatal Mouse Brain is the latest addition to Academic Press' list of atlases for neuroscientists and neuroscience students. It fills an urgent need for a comprehensive atlas of the developing mouse brain for use in studies of both normal and abnormal development. High-quality photomicrographs of brain sections are depicted in sagittal, coronal, and horizontal planes for four gestational age groups. Each photomicrograph is accompanied by a fully labeled, precision-drawn diagram for easy identification of brain structures. Researchers and students using normal, transgenic, or mutant mouse preparations in developmental neurobiology, neurotoxicology, and biotechnology will welcome this meticulously assembled and accessible guide.

  • Providing Pharmacological Access to the Brain

    Alternate Approaches
    • 1 Edición
    • Volumen 21
    • P. Michael Conn + 1 más
    • Inglés
    This volume focuses on contemporary approaches for delivering experimental and therapeutic agents into the brain. The contributions provide methodological details that are typically not available in the literature. Subtleties and shortcuts critical to each procedure are included to facilitate their use by both the experienced researcher and novice.

  • Presynaptic Receptors and Neuronal Transporters

    Official Satellite Symposium to the IUPHAR 1990 Congress Held in Rouen, France, on 26–29 June 1990
    • 1 Edición
    • S.Z. Langer + 2 más
    • Inglés
    Advances in the Biosciences, Volume 82: Presynaptic Receptors and Neuronal Transporters documents the proceedings of the Official Satellite Symposium to the IUPHAR 1990 Congress held in Rouen, France on June 26-29, 1990. The first part of this book deals with the extensive and still increasing list of presynaptic release-modulating auto and heteroreceptors, emphasizing the various subtypes of presynaptic receptors that are characterized by functional studies, both in vitro and in vivo, using a number of experimental approaches. The next chapters are devoted to the molecular pharmacology of presynaptic receptors, of which can interfere with G proteins and modify the activity of adenylate cyclase, guanylate cyclase, or protein kinase C. The purification and molecular biology of transporter systems, including cloning and sequencing of the neuronal sodium-ion coupled GABA transporter are also discussed. This compilation concludes with insights on the function of presynaptic receptors and neuronal transporters both in the periphery and in the CNS, as well as their ubiquitous locations and physiological roles. This publication is a good reference for students and individuals researching on the presynaptic autoreceptors and neurotransmitters.

  • Clinical Methods of Neuro-Ophthalmologic Examination

    • 1 Edición
    • Alfred Kestenbaum
    • Inglés
    Clinical Methods of Neuro-Ophthalmologic Examination presents the clinical methods of ophthalmologic examination that may be helpful in neurologic differential diagnosis. Neuro-ophthalmologic examination has developed in two directions: the more precise methods and the unrefined yet fairly exact methods, such as diagnostic measurement by means of a simple ruler. This book is based on lectures delivered by the author to neurologists and ophthalmologists. This book is composed of 13 chapters and begins with a presentation of anatomic details that are important for the understanding of the various signs and symptoms. The next chapters examine the development of simple perimetry into quantitative perimetry and angio-scotometry, as well as the pathology of the optic nerve. Considerable chapters are devoted to intensive discussions on group of diseases that affect in a parallel way the central nervous system and the eye, such as chiasmal and retrochiasmal lesions, nystagmus, symmetrical eye movement disturbance, palpebral fissure, hemicrania. The final chapter outlines a routine neuro-ophthalmologic... examination. This book is directed toward neurologists and ophthalmologists.

  • Ion Channels of Excitable Cells

    • 1 Edición
    • Volumen 19
    • Toshio Narahashi + 1 más
    • Inglés
    Because of the highly significant and widely recognized roles of ion channels in physiology, pathophysiology, pharmacology, and toxicology, the term ion channel has now become a household word in the biomedical sciences. This volume covers preparations and techniques for the study of various ion channels. Both voltage-gated and ligand-gated ion channels of neurons, axons, and cardiac and smooth muscles are covered. It includes not only patch clamp techniques but molecular biology and imaging techniques as well.

  • Computers and Computations in the Neurosciences

    • 1 Edición
    • P. Michael Conn
    • Inglés
    Methods in Neurosciences, Volume 10: Computers and Computations in the Neurosciences discusses the use of computers in the neurosciences. The book deals with data collection, analysis, and modeling, with emphasis on the use of computers. Section I involves data collection using a personal microcomputer system. One paper presents a tutorial on using a PC-based motor control composed of an electronic circuit to adjust the motion of a light microscope stage through a software program. Other papers discuss computer methods in nuclei cartography and a computer-assisted quantitative receptor autoradiography in studying receptor density distribution. Section II deals with data analysis and some computer programs for kinetic modeling of gene expression in neurons. The book also discusses a computerized analysis of opioid receptor heterogeneity by ligand binding in test animals using computerized programs instead of employing manual or graphical methods. Computerized curve-fitting allows the researcher to utilize a more precise mathematical model to describe the binding of one ligand to one class of sites. Section III evaluates data modeling and simulations and describes the practicality of using computers to design model ion channels. Another paper discusses a graphical interaction program called MEMPOT to simulate an electrophysiological investigation of the properties of the membrane potential in stimulated cells. The book also presents a quantitative data gathered from computer simulation of the factors that affect neuronal density per measured sections. The book is suitable for microbiologists, biochemists, neuroscientists, and researchers in the field of medical research, as well as for advanced computer programmers in medical research work.

  • Developmental Neuropsychobiology

    • 1 Edición
    • William T Greenough + 1 más
    • Inglés
    Developmental Neuropsychobiology is a compendium of papers that deals with developmental neuroscience and developmental psychology, as well as the broad range of approaches toward brain-behavior development. One paper reviews the embryonic mechanisms including the pattern formation that develops in a single fertilized egg, particularly focusing on limb innervation as a special case of pattern formation. Another paper discusses the regulation of nerve fiber elongation during embryogenesis. One author analyzes the pathways and changing connections in the nervous system of the insect: he shows that manipulating neural organization by grafting results in the ability of the transplanted sensory cells to find the proper central connections. Another paper reviews the sex differences in developmental plasticity of behavior and the brain. These differences point to the vulnerability of males during development to incidences of autism, dyslexia, or cerebral palsy compared to females. One paper also examines alternative perceptions of parent- offspring relationships. This collection can prove helpful for researchers, students, and academicians involved in the disciplines of biological or psychological sciences.

  • Progress in Behavior Modification

    Volume 3
    • 1 Edición
    • Michel Hersen + 2 más
    • Inglés
    Progress in Behavior Modification, Volume 3, is a multidisciplinary serial publication that encompasses the contributions of psychology, psychiatry, social work, speech therapy, education, and rehabilitation. This serial aims to meet the need for a review publication that undertakes to present yearly in-depth evaluations that include a scholarly examination of theoretical underpinnings, a careful survey of research findings, and a comparative analysis of existing techniques and methodologies. The discussions center on a wide spectrum of child and adult disorders. The present volume opens with a chapter on behavior modification and hypnosis. This is followed by separate chapters on applications of behavior modification procedures in classroom settings; smoking behavior modification; and psychotherapy outcome research. Subsequent chapters deal with the behavioral approach to teaching learning disabled children; evaluation of animal analogues of behavioral treatment; therapy for sexual dysfunction; and research in the area of transfer of training of operant treatment effects with children.

  • Methods in Neurotransmitter and Neuropeptide Research

    • 1 Edición
    • Volumen 11
    • S.H. Parvez + 2 más
    • Inglés
    This two-part book provides the most advanced biochemical and histochemical analytical methods on neurotransmitters, neuromodulators, and neuropeptides described by international specialists. The biochemical methods include liquid chromatography/elect... liquid chromatography/fluor... and chemiluminescence detection, gas chromatography or liquid chromatography with mass spectrometry, and immunoassays.Morphol... and physiological methods are also described, including immunohistochemistry... in situ hybridization, in vivo microdialysis, electrophysiological analysis, microwave irradiation, electrophysiological analysis, micro-anatomical dissection, peptide sequence analysis, quantitative autoradiographic analysis, and isolated CNS preparations. The neurotransmitters and neuropeptides include catecholamines, indoleamines, histamine, polyamines, and various neuropeptides, and their related enzymes. The book is the most comprehensive, advanced and versatile volume on the biochemical, morphological and physiological analysis of neurotransmitters and neuropeptides.

  • Dale's Principle and Communication between Neurones

    Based on a Colloquium of the Neurochemical Group of the Biochemical Society, Held at Oxford University, July 1982
    • 1 Edición
    • Neville N. Osborne
    • Inglés
    Dale's Principle and Communication Between Neurones is based on a colloquium of the Neurochemical Group of the Biochemical Society, held at Oxford University, July 1982. This book focuses on communication between neurones by means of chemical signals. The book contains an introductory chapter by V. P. Whittaker and nine further chapters on various aspects of the chemical communication processes between neurones. Topics covered include chemical communication between excitable cells; the neuroendocrine division of the nervous system; evidence for a neurone having the capacity to use two chemicals in the same process; and non-synaptic interneuronal communication. Each article is based on the excellent lectures given by the main authors and the discussion which ensued in the one-day colloquium held in Oxford. The final chapter is a specially invited contribution by Drs. Polak and Varndell, who agreed to produce an article on their new method of localising transmitter-like molecules at the electron-microscopic level.

  • An Introduction to the Study of the Nervous System

    • 2 Edición
    • E. E. Hewer + 1 más
    • Inglés
    An Introduction to the Study of the Nervous System covers topics about the minute structure and functions of the nervous system. The book discusses the minute and gross anatomy of the various parts of the nervous system; the degenerative and regenerative changes following section of the nerves; and the descending and ascending tracts of the spinal cord. The text then describes the cerebellar connections; the deep connections of the cranial nerves; and the microscopic structure of the cortex of the cerebellum and of the cerebrum. The distribution, source, circulation and absorption, pressure, and normal composition of the cerebrospinal fluid and the parts and functions of the autonomic nervous system are also considered. The book further tackles the normal physiology of the sensory and motor paths; the results of interference with the general sensory path at various levels; and the visual path and interference therewith. The text also discusses the cochlear and olfactory paths and the interference therewith and the levels of integration and mechanism of coordinated muscular movement. Students taking courses related to neurology will find the book useful.

  • Neurobiology of Cytokines, Part B

    • 1 Edición
    • Volumen 17
    • P. Michael Conn + 1 más
    • Inglés
    Recent data suggest a critical role for cytokines in the regulation of brain and endocrine function under normal physiological conditions. The aim of this volume and its companion Volume 16 is to provide an overview of the effects of cytokines in the brain and in the endocrine system.

  • Neurotrauma

    Treatment, Rehabilitation, and Related Issues
    • 1 Edición
    • Michael E. Miner + 1 más
    • Inglés
    Neurotrauma: Treatment, Rehabilitation, and Related Issues discusses the issues pertinent to central nervous system trauma. This book is organized into three parts encompassing 17 chapters that tackle the study and management of head injury, including the range of treatment, rehabilitation, and reintegration into the community. Some of the topics covered in the book are the demography of head injury in the United States; cardiopulmonary changes after head injury; management of intracranial hypertension; mechanisms and management of posttraumatic epilepsy; metabolic responses to severe head damage; and evoked responses monitoring in the intensive care unit. Other chapters deal with the auditory assessment of neural trauma, the issues in the evaluation of rehabilitation effects, and the sociological parameters affecting comparisons of long-term outcome. A chapter is devoted to the sensory evoked responses in the diagnosis of brain death. The final chapter focuses on the outcome and recovery of children after experiencing head injury. The book can provide useful information to doctors, neurologists, students, and researchers.

  • Selected Topics from Neurochemistry

    • 1 Edición
    • Neville N. Osborne
    • Inglés
    This book contains up-dated versions of articles which proved very popular when first published in Neurochemistry International. The articles draw attention to developments in a specific field perhaps unfamiliar to the reader, collating observations from a wide area which seem to point in a new direction, giving the author's personal view on a controversial topic, or directing soundly based criticism at some widely held dogma or widely used technique in the neurosciences.

  • Neural Modeling and Neural Networks

    • 1 Edición
    • F. Ventriglia
    • Inglés
    Research in neural modeling and neural networks has escalated dramatically in the last decade, acquiring along the way terms and concepts, such as learning, memory, perception, recognition, which are the basis of neuropsychology. Nevertheless, for many, neural modeling remains controversial in its purported ability to describe brain activity. The difficulties in "modeling" are various, but arise principally in identifying those elements that are fundamental for the expression (and description) of superior neural activity. This is complicated by our incomplete knowledge of neural structures and functions, at the cellular and population levels. The first step towards enhanced appreciation of the value of neural modeling and neural networks is to be aware of what has been achieved in this multidisciplinary field of research. This book sets out to create such awareness. Leading experts develop in twelve chapters the key topics of neural structures and functions, dynamics of single neurons, oscillations in groups of neurons, randomness and chaos in neural activity, (statistical) dynamics of neural networks, learning, memory and pattern recognition.

  • Methods in Neuropsychology

    • 1 Edición
    • M. A. Jeeves + 1 más
    • Inglés
    Efforts to relate neuroscience and anatomy with ethology and psychology have involved an ever widening group of scientists from diverse backgrounds and it has become increasingly evident that interaction is harder to arrange. This book is offered as a first attempt to address some of these interdisciplinary problems. First, it aims to provide a critical evaluation of some of the principal methods used by neuropsychologists in research and assessment. Second, it provides short evaluations of the methods which they use to shed further light on brain dysfunction. In this way it is hoped that it offers a further insight into this multidisciplinary field.

  • Pain Syndromes in Neurology

    Butterworths International Medical Reviews
    • 1 Edición
    • Howard L. Fields
    • Inglés
    Pain Syndromes in Neurology deals with the diagnosis and treatment of painful conditions associated with dysfunction of the peripheral or central nervous system. It discusses advances in three areas: first, the normal anatomy and physiology of pain; second, the pathophysiology of damaged sensory neurons; and third, the diagnosis and treatment of patients with neuropathic pain. The book begins with a discussion of neural mechanisms relevant to pain perception along with a brief review of neuropathic pain. This is followed by separate chapters on hyperalgesia following cutaneous injury; the importance of peripheral processes in the etiology of neuropathic and radiculopathic pain; and mechanisms by which sympathetic efferent fibers contribute to the occurrence of pain. Subsequent chapters cover the diagnosis and treatment of reflex sympathetic dystrophy; pain in generalized neuropathies; surgical treatment of pain; clinical features and management of postherpetic neuralgia; diagnosis of cancer pain syndromes; and drugs in the management of chronic pain.

  • Neurocutaneous Diseases

    A Practical Approach
    • 1 Edición
    • Manuel Rodriguez Gomez
    • Inglés
    Neurocutaneous Diseases is a systematic presentation limited to diseases that affect both of the nervous system and skin of humans. Neurologists and dermatologist will find knowledge of these diseases of real clinical value. Many of the diseases described in these pages do not affect the skin and nervous system simultaneously. Many of these diseases, mostly not well understood, may stimulate new lines of scientific inquiry, for understanding of a pathologic change in easily accessible dermal cells that promises to clarify a more recondite brain disease. This book is organized into five main parts. The chapters describe different types of diseases including those with autosomal dominant inheritance, those with autosomal recessive inheritance, those with x-linked inheritance, those with unknown or multiple inheritance and congenital and vascular anomalies. These diseases include neurofibromatosis, Cockayne's Syndrome, adrenoleukodystrophy... albinism and neurocutaneous melanosis. This book will be of interest to dermatologists and neurologists.

  • Microsurgery

    Applied to Neurosurgery
    • 1 Edición
    • M. G. Yaşargil
    • Inglés
    Microsurgery Applied to Neurosurgery focuses on microsurgical approaches to cerebrospinal lesions, including plastic surgery, suturing techniques, instruments for microsurgery, and microsurgical operations. The manuscript first offers information on the history of microsurgery and the operating microscope. Discussions focus on bipolar electric coagulation, plastic surgery, peripheral nerves, clinical application, binocular diploscope, automatic microscope stand, sterile covering of the microscope, and magnification. The text also elaborates on the instruments for microsurgery and suturing techniques. The publication takes a look at experimental microsurgical operations in animals and reconstructive and constructive surgery of the cerebral arteries in man. The manuscript also ponders on intracranial tumors and transnasal-transsphe... approach to the pituitary gland. Topics include transsphenoidal approach, suboccipital transmeatal approach, spinal tumors, and preoperative radiological study. The manuscript is a dependable reference for health professionals and readers interested in microsurgery.

  • Quantitative and Qualitative Microscopy

    • 1 Edición
    • P. Michael Conn
    • Inglés
    Methods in Neurosciences, Volume 3: Quantitative and Qualitative Microscopy is a collection of papers that deals with microscopic techniques in statistical measures. This volume describes microscopy using sophisticated stains and dyes to advance observation of tests and experiments. Section I describes autoradiography including micro chemical methods, high-resolution autoradiography, and single- or double-label quantitative autoradiography for use in imaging of brain activity patterns or determining cerebral physiology. Section II discusses the quantification of structures through statistical and computational methods including dynamic video imaging technology. Section III explains the use of tracers, toxins, or dyes in tracing neuronal connections. One paper addresses the use of small injections of axonally transported fluorescent tracers. Section IV explains staining technology such as using the silver impregnation method for frozen sections of human nervous tissue that are gathered from tissues preserved in formalin. Section V addresses freezing techniques and those using freeze-fracture methods in neurobiology. The text also discusses cryoprotection and other freezing methods to control ice crystals found in fixed or unfixed brain tissues. Section VI presents the combined and high-resolution methods in polarization microscopy and microscopic investigations. Cellular biologists, micro-chemists, and scientific researchers in the field of micro- and cellular biology will appreciate this book.

  • Minireviews of the Neurosciences from Life Sciences

    • 1 Edición
    • Bernard B. Brodie + 1 más
    • Inglés
    Minireviews of the Neurosciences from Life Sciences is a collection of minireviews of research in the neurosciences and originally published by the Journal of Life Sciences. These minireviews cover a wide range of topics such as the function and organization of the chromaffin vesicle; taste receptor proteins; the role of cyclic nucleotides in visual excitation; and regulation of tryptophan and tyrosine hydroxylase. Comprised of 34 chapters, this volume begins with a discussion on Na,K-ATPase, followed by an analysis of the function and organization of the chromaffin vesicles of the adrenal medulla. Subsequent chapters focus on the nerve growth factor and the acetylcholine receptor; sympathetic regulation of thyroid hormone secretion; the role of cyclic AMP in the action of antidiuretic hormone on the kidney; and neurochemical correlates of synaptically active amino acids. The role of calcium in the central effects of biogenic amines is also examined, along with the brain mechanisms underlying motor control, molecular coding of memory, and opiate receptors. This book should be of value to teachers, researchers, and students.

  • Peripheral Neuropathies

    Proceedings of the International Symposium on Peripheral Neuropathies Held in Milan, Italy, on June 26–28, 1978
    • 1 Edición
    • N. Canal + 1 más
    • Inglés
    Peripheral Neuropathies compiles lectures presented at the Symposium on Peripheral Neuropathies held in Milan, Italy on June 26-28, 1978. This book covers the basic problems in peripheral nerve pathology; axonal transport; neuropathies in chronic renal failure; peripheral neuropathies in diabetes; compression neuropathies; and metabolic, genetic, and inflammatory neuropathies. This text also discusses topics such as filamentous inclusions in Schwann cell nuclei; autonomie dysfunction and myokymia in gold neuropathy; study of the effect of gangliosides on experimental carbon disulfide neuropathy; and peripheral nerve changes in Refsum's disease before and after treatment. This compilation is a useful source of information for students and researchers conducting investigative work on peripheral neuropathy.

  • Contemporary Neurology

    • 1 Edición
    • M.J.G. Harrison
    • Inglés
    Contemporary Neurology compiles a large series of papers on the commonest neurological problems. This book discusses the management of epilepsy, involuntary movements, nerve and muscle diseases, and multiple sclerosis. The areas on infections, cerebrovascular disease, trauma, intracranial pressure, and vertebral column are also elaborated. This text likewise describes medical procedures on how to do a lumbar and cisternal puncture. Other topics include headache in children, hyperventilation, dizziness, funny turns—neurological, dysarthria, facial pain, and nystagmus. The weakness of the legs, loss of memory, coma, brain death, complications of alcoholism, and stupor and akinetic mutism are also covered. This publication is valuable to clinicians and examination candidates preparing for the DPM, MRCP (UK) and Neurology/Psychiatry “Boards”.

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