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Elsevier

Libros en Neurociencia

  • Encyclopedia of Sleep

    • 1 Edición
    • Clete Kushida
    • Inglés
    In a world of 24-hour media saturation, sleep has become an increasingly fraught enterprise. The award-winning four-volume Encyclopedia of Sleep, Four Volume Set is the largest reference, either online or in print, on the subject of sleep. Written to be useful for the novice and the established researcher and clinician, Topic areas will include sleep across the life cycle and in other species, sleep and women, sleep and the elderly, pediatric sleep, sleep deprivation and loss, sleep mechanisms, sleep physiology and pathophysiology, sleep disorders, neurobiology, chronobiology, pharmacology, and impact of other disorders on sleep. Recognizing the many fields that are connected to sleep science, the editorial team has been carefully chosen to do justice to this highly interdisciplinary field of study. The steady growth of researchers and clinicians in the sleep field attests to the continued interest in the scientific study of sleep and the management of patients with sleep disorders, and anyone involved in this exciting field should find this work to be an invaluable reference.

  • Implantable Sensor Systems for Medical Applications

    • 1 Edición
    • Andreas Inmann + 1 más
    • Inglés
    Implantable sensor systems offer great potential for enhanced medical care and improved quality of life, consequently leading to major investment in this exciting field. Implantable sensor systems for medical applications provides a wide-ranging overview of the core technologies, key challenges and main issues related to the development and use of these devices in a diverse range of medical applications.Part one reviews the fundamentals of implantable systems, including materials and material-tissue interfaces, packaging and coatings, microassembly, electrode array design and fabrication, and the use of biofuel cells as sustainable power sources. Part two goes on to consider the challenges associated with implantable systems. Biocompatibility, sterilization considerations and the development of active implantable medical devices in a regulated environment are discussed, along with issues regarding data protection and patient privacy in medical sensor networks. Applications of implantable systems are then discussed in part three, beginning with Microelectromechanic... systems (MEMS) for in-vivo applications before further exploration of tripolar interfaces for neural recording, sensors for motor neuroprostheses, implantable wireless body area networks and retina implants.With its distinguished editors and international team of expert contributors, Implantable sensor systems for medical applications is a comprehensive guide for all those involved in the design, development and application of these life-changing technologies.

  • Epigenetic Regulation in the Nervous System

    Basic Mechanisms and Clinical Impact
    • 1 Edición
    • J. David Sweatt + 3 más
    • Inglés
    Epigenetic Regulation in the Nervous System addresses current understanding of the roles of epigenetic processes at the molecular/cellular level, their impact on neural development and behavior, and the potential roles of these mechanisms in neurological and psychiatric disorders. This award-winning volume spans molecular epigenetics, development, cellular physiology and biochemistry, synaptic and neural plasticity, and behavioral models, and is unique in covering epigenetically based disorders of the central nervous system.Behavioral epigenetics is the study of how environmental factors alter behavior, addressing the fundamental mechanisms that shape development and individual vulnerability/resili... to adverse behavioral outcomes. By understanding the molecular mechanisms involved in epigenetic modulation, researchers may be able to develop targeted therapies for those individuals in whom it malfunctions.Edited by the most highly regarded leaders in the field, this book offers a comprehensive review of behavioral epigenetics and a balanced treatment of the strengths and weaknesses in experimentation in this area. Covering background material as well as topics of current interest, it serves both as a cutting-edge resource and a foundational reference. The book will benefit neuroscience researchers and graduate students with an interest in the links between gene regulation and behavior, as will clinicians dealing with disorders such as addiction, depression, and schizophrenia.

  • Functional Neural Transplantation III

    Primary and Stem Cell Therapies for Brain Repair, Part II
    • 1 Edición
    • Volumen 201
    • Inglés
    This issue of Progress in Brain Research is split over 2 volumes, bringing together cutting-edge research on Functional Neural Transplantation. The 2 volumes review current knowledge and understanding, provide a starting point for researchers and practitioners entering the field, and build a platform for further research and discovery.

  • Axon Growth and Regeneration: Part 2

    • 1 Edición
    • Volumen 106
    • Inglés
    Leading authors review state-of-the-art in their field of investigation and provide their views and perspectives for future research. Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered. All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist

  • Axon Growth and Regeneration: Part 1

    • 1 Edición
    • Volumen 105
    • Inglés
    Published since 1959, International Review of Neurobiology is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research. This volume reviews existing theories and current research surrounding Axon Growth and Regeneration.

  • Emerging Horizons in Neuromodulation

    New Frontiers in Brain and Spine Stimulation
    • 1 Edición
    • Volumen 107
    • Inglés
    This issue of International Review of Neurobiology brings together cutting-edge research on neuromodulation. It reviews current knowledge and understanding, provides a starting point for researchers and practitioners entering the field, and builds a platform for further research and discovery.

  • Head and Neck Cancer, An Issue of Neuroimaging Clinics

    • 1 Edición
    • Volumen 23-1
    • Patricia A. Hudgins + 1 más
    • Inglés
    This issue reviews the state of the art in imaging head and neck cancer. Articles cover topics on Rationale for Staging by Imaging; Oral Cavity Cancer; Oropharynx; Nasopharyngeal Carcinoma; Pitfalls in Staging Squamous Cell Carcinoma of the Hypopharynx; Larynx; Major Salivary Glands; Thyroid Cancer; Lymph Nodes; Image-Guided Tissue Sampling; and Surgical Perspective.

  • Functional Neural Transplantation III

    Primary and Stem Cell Therapies for Brain Repair, Part I
    • 1 Edición
    • Volumen 200
    • Inglés
    This issue of Progress in Brain Research is split over 2 volumes, bringing together cutting-edge research on functional neural transplantation. The 2 volumes review current knowledge and understanding, provide a starting point for researchers and practitioners entering the field, and build a platform for further research and discovery.

  • Neurological Rehabilitation

    • 1 Edición
    • Volumen 110
    • Michael P. Barnes + 1 más
    • Inglés
    Neurological Rehabilitation is the latest volume in the definitive Handbook of Clinical Neurology series. It is the first time that this increasing important subject has been included in the series and this reflects the growing interest and quality of scientific data on topics around neural recovery and the practical applications of new research. The volume will appeal to clinicians from both neurological and rehabilitation backgrounds and contains topics of interest to all members of the multidisciplinary clinical team as well as the neuroscience community. The volume is divided into five key sections. The first is a summary of current research on neural repair, recovery and plasticity. The authors have kept the topics readable for a non-scientific audience and focused on the aspects of basic neuroscience that should be most relevant to clinical practice. The next section covers the basic principles of neurorehabilitation, including excellent chapters on learning and skill acquisition, outcome measurement and functional neuroimaging. The key clinical section comes next and includes updates and reviews on the management of the main neurological disabling physical problems, such as spasticity, pain, sexual functioning and dysphagia. Cognitive, emotional and behavioural problems are just as important and are covered in the next section, with excellent chapters, for example, on memory and management of executive dysfunction. The final part draws the sections on symptom management together by discussing the individual diseases that are most commonly seen in neurorehabilitation and providing an overview of the management of the disability associated with those disorders. The volume is a definitive review of current neurorehabilitation practice and will be valuable to a wide range of clinicians and scientists working in this rapidly developing field.

  • Bioinformatics of Behavior: Part 2

    • 1 Edición
    • Volumen 104
    • Inglés
    This issue of International Review of Neurobiology is split over 2 volumes, bringing together cutting-edge research on Bioinformatics of Behavior. The 2 volumes review current knowledge and understanding, provide a starting point for researchers and practitioners entering the field, and build a platform for further research and discovery.

  • Bioinformatics of Behavior: Part 1

    • 1 Edición
    • Volumen 103
    • Inglés
    This issue of International Review of Neurobiology is split over 2 volumes, bringing together cutting-edge research on Bioinformatics of Behavior. The 2 volumes review current knowledge and understanding, provide a starting point for researchers and practitioners entering the field, and build a platform for further research and discovery.

  • Cellular and Molecular Neurobiology

    • 2 Edición
    • Constance Hammond
    • Inglés
    This Second Edition, is the new, thoroughly revised edition of the established and well-respected authoritative text in the field. Cellular and Molecular Neurobiology is hypothesis driven and firmly based on numerous experiments performed by experts in the field. Seven new chapters (five new and two totally rewritten) complement and expand on the first edition and are written in a way that encourages students to ask questions. Additionally, new, groundbreaking research data on dendritic processing is presented in a very easy-to-understand format.

  • Mass Action in the Nervous System

    • 1 Edición
    • Bozzano G Luisa
    • Inglés
    Mass Action in the Nervous System: Examination of the Neurophysiological Basis of Adaptive Behavior through the EEG focuses on the neural mechanisms and the behavioral significance of the electroencephalogram... with emphasis on observations made on the mammalian olfactory system. Organized into seven chapters, this book begins with a brief nonmathematical review of the concept of the neuron and the interrelations among neurons that lead to the formation of interactive masses. Some chapters follow on the linear properties of neurons and their parts; the ionic hypothesis; the nonlinear input-output relations of neurons in masses expressed in terms of amplitude-dependent coefficients in linear differential equations; and the relations between the states of activity of neurons. Subsequent chapters describe the properties resulting from feedback within neural masses; the effects of the nonlinearities in the input-output relations of neurons on the behavior of masses; and some inferences concerning the mechanisms of neural signal processing at the level of neural masses. The book is a model for an advanced text in neurophysiology, and some understanding is assumed of the elements of the fields of linear analysis, probability, statistics, theory of potential, neuroanatomy, electrophysiology, neuropharmacology, and experimental psychology.

  • The Biology and Management of Lobsters

    Physiology and Behavior
    • 1 Edición
    • Inglés
    This two-volume work presents a summary and review of the current state of lobster biology, ecology, physiology, behavior, and management. It emphasizes the biology of clawed lobsters (Nephropidae) and spiny lobsters (Palinuridae), with attention also given to slipper lobsters (Scyllaridae) and coral lobsters (Synaxidae).The first chapter of Volume 1 provides an overview of the general aspects of lobster biology that serves as an introduction for readers of both volumes. Subsequent chapters examine the topics of growth, neurobiology, reproduction, nutrition, pathology, social behavior, and migration patterns.The chapters in Volume II consider the ecology, population dynamics, fishery biology, and aquaculture of spiny and clawed lobsters. The topics selected in both volumes represent areas of current research whose findings have not been previously synthesized into a coherent form.An important feature of these volumes is the emphasis on the interaction between biology and management and culture. Many of the contributors have done research in both applied and basic biology and can articulate both points of view. The interaction between basic and applied research is of fundamental importance in these volumes in which management aspects of the research have been integrated with the basic biology of lobsters.The Biology and Management of Lobsterswill be of interest to crustacean biologists, marine biologists and ecologists, zoologists, physiologists, animal behavior researchers, aquaculturalists, fisheries biologists and managers of fisheries, neurobiologists, pathologists, and food scientists.

  • Adenosine in the Nervous System

    • 1 Edición
    • Richard E. Stone
    • Inglés
    This volume in a series on neuroscience provides an overview of the last 20 years of research into the biochemistry, physiology,pharmacol... and clinical therapeutic potential of adenosine and its analogues in the nervous system. Among the topics covered are adenosine transport in nervous systemtissues, adenosine production and metabolism and the electropharmacology of adenosine.

  • Foundations of Modern Auditory Theory

    • 1 Edición
    • Jerry Tobias
    • Inglés
    Foundations of Modern Auditory Theory, Volume I is an 11-chapter text that covers the basic auditory processes. This volume deals first with the electrophysiological and conditioning data that reflect periodicity perception, the analysis of high-frequency tones, and the mechanisms and effects of auditory masking. These topics are followed by discussions on the poststimulatory auditory fatigue and adaptation; the theoretical bases necessary for an understanding of the critical band’s ubiquity; and the mechanical events in transformation process occurring in cochlea. This volume describes the anatomical structure and electrophysiological action of the cochlea and further explores ear models to study the mechanical properties of the auditory system and the basic neural transmission processes and their properties. The concluding chapters look into the distinct patterns of disorder in psychoacoustic function and the perception of musical stimuli. This book is an ideal source for teachers and students who wish to understand the mechanisms of the auditory system.

  • Learning and Memory

    A Biological View
    • 2 Edición
    • Bozzano G Luisa
    • Inglés
    Learning and Memory: A Biological View is a comprehensive textbook about the neurobiology of learning and memory. Topics covered range from anatomical correlates of neuronal plasticity to drugs that modulate learning and memory, along with biochemical correlates of learning and memory. The effect of aging on memory and electrophysiological analogs of memory are also discussed. Comprised of 12 chapters, this book begins with a review of historical traditions that influenced research on the biological basis of learning and memory. Experimental results indicating that the engram for a simple classically conditioned skeletal response may be in the cerebellum are also summarized. The next chapter stresses the importance of anatomical mechanisms that could mediate learning, plasticity, and memory storage in young and adult animals. Subsequent chapters focus on the influence of peripheral hormones, including opioid peptides, on learning and memory; the contribution of individual neurotransmitter systems to learning; the psychopathology of aging; and long-term potentiation. Learning in complex vertebrate systems and direct stimulation of various brain nuclei are also considered. The final chapter presents a neurobehavioral analysis of the structure of memory formation that utilizes lesions and explores human memory pathology. This monograph is intended for advanced undergraduate students, graduate students, and research workers in the field of memory.

  • Differences in Visual Perception

    The Individual Eye
    • 1 Edición
    • Jules Davidoff
    • Inglés
    Differences in Visual Perception: The Individual Eye examines the differences in visual perception that can occur in various circumstances when observers perceive the “same” event. More specifically, the book considers the distinction between “what happens when a person looks at the world directly and when he sits with his eyes closed and thinks.” This book is organized into five chapters and begins with an overview of differences in perception that are in operation for only a short time, emphasizing the distinction between short and long-term effects and at what point “short” becomes “long.” The reader is then introduced to the development of perception, touching on topics such as the nature-nurture issue, visual acuity and visual discrimination, color-vision, space perception, and attentional processes. The ambiguity of the stimulus is also discussed, along with the perceptual theory known as “transactionalism,” how the visual world is interpreted, and the nature of the input to the visual system. The theme that runs throughout this work is the fact that the same external input does not necessarily bring about in all of us the same perception. This book will prove useful to students as well as established researchers interested in visual perception and cognition.

  • Hormones, Brain Function And Behavior

    Proceedings of a Conference on Neuroendocrinology Held at Arden House, Harriman, New York, 1956
    • 1 Edición
    • Hudson Hoagland
    • Inglés
    Hormones, Brain Function, and Behavior brings together the proceedings of a conference on neuroendocrinology held in May 1956 in New York. The papers explore selected aspects of hormone actions in relation to brain function and behavior and cover topics ranging from the effects of steroid hormones on the nervous system to the behavioral consequences of sex hormones and thyroid hormones. Serotonin, epinephrine, and their metabolites are also discussed in relation to experimental psychiatry. This monograph is comprised of 12 chapters and begins with an assessment of steroid hormones in relation to neuropsychiatric disorders, as well as the influence of adrenocortical steroids on brain function and metabolism. Subsequent chapters focus on the genetic and psychological determinants of sexual behavior patterns; the role of serotonin in mental disorders; the effect of thyroid hormones on appetite for alcohol and alcoholic beverages in rats; and the link between thyroid hormones and mental health. The biochemistry of serotonin and its physiological implications are also examined. This text will appeal to biologists, neuropharmacologists... neuropsychiatrists, and psychologists.

  • Hormonally Induced Changes to the Mind and Brain

    • 1 Edición
    • Bozzano G Luisa
    • Inglés
    Describing the latest findings in both clinical and laboratory research, this volume investigates the behavioral and neural affects of endocrine activity in animals and humans. Each chapter discusses the relationship between normal endocrine control of behavior and the pathological consequences that result from endocrine abnormalities. The relevance to mental health, and basic regulatory homeostatic events are balanced with a basic understanding of how hormones affect behavior and the brain. The book is written to appeal to a wide audience of readers, from the educated lay person to the seasoned M.D. and research scientist. Chapter topics include the effects of endocrine activity on homeostasis, sexual behavior, aggression, circadian rhythms, and affective disorders, in addition to discussing steroid abuse, adrenal steroid effects on the brain, and a detailed investigation on the effects of cholecystokinin and oxytocin.

  • Intracellular Messengers

    • 1 Edición
    • C.M. Taylor
    • Inglés
    This important new reference work offers an outstanding collection of articles devoted to the discussion of "intracellular messengers". Extracellular stimuli ("first messengers") bind to receptors on the plasma membrane of cells to trigger changes in the concentration of intracellular messengers ("second messengers") which leads, in turn, to changes in cellular activity. However, the intracellular activities of so called "third messengers" may also be involved complicating the concept of a rigid sequence of events between receptor and response. The preference for the term "intracellular messengers", and, hence, the title of this volume, recognizes that a complex web of interactions between intercellular messengers determines the concentrations and ultimate effects of each.

  • Neuroepidemiology

    Theory and Method
    • 1 Edición
    • Bozzano G Luisa
    • Inglés
    As a collection of neuroepidemiology papers, this book captures the range and excitement of the discipline. Researchers in the field have been at the forefront in the study of slow viruses, retroviral epidemiology, chronic neuroloical diseases, as well as injuries and other disabilities of the neurological system. The intersection of epidemiology, neurology, and behavioral/social science is a unique feature of this book. Furthermore, Molgaard's collection differs from similar titles in that it focuses on minorities and international work in neuroepidemiology.

  • Biology of Conidial Fungi, Volume 1

    • 1 Edición
    • Garry T. Cole
    • Inglés
    Biology of Conidial Fungi, Volume I covers the history, classification, distribution, and ecology of conidial fungi. Conidial fungi are anamorphic (asexual) fungi of presumed ascomycetous or basidiomycetous origin. Organized into three parts encompassing 14 chapters, the book begins with a brief introduction to the history of conidial fungi. It then describes the systematics, classification, and taxonomy of a particular group of fungi, such as Hyphomycetes, Celomycete, conidial yeasts, and conidial lichen-forming fungi. The dimorphism and pleomorphism properties of these fungi are also examined. Significant topics on the general aspects of the soil, freshwater, marine, and aerial ecology of conidial fungi are considered in other chapters. This volume is of value to researchers and advanced students who are interested in the basic aspects of conidial fungi.

  • Visual Perception

    The Neurophysiological Foundations
    • 1 Edición
    • Lothar Spillmann + 1 más
    • Inglés
    This book presents an interdisciplinary overview of the main facts and theories that guide contemporary research on visual perception. While the chapters cover virtually all areas of visual science, from philosophical foundations to computational algorithms, and from photoreceptor processes to neuronal networks, no attempt has been made to provide an exhaustive treatment of these topics. Rather, researchers from such diverse disciplines as psychology, neurophysiology, anatomy, and clinical vision sciences have worked together to review some of the most important correlations between perceptual phenomena and the underlying neurophysiological processes and mechanisms. The book is thus intended to serve as an advanced text for graduate students and as a guide for all vision researchers to understanding current progress outside their specialized fields of interest.

  • Thirst and Sodium Appetite

    Physiological Basis
    • 1 Edición
    • Sebastian Grossman
    • Inglés
    Thirst and Sodium Appetite: Physiological Basis describes the phenomenon of thirst and the mechanisms that define the need for water. Thirst and appetite has generated much study and research about the physiological, endocrinological, and pharmacological mechanisms that influence water intake. However, in this book, other concerns have been emphasized, such as the significance of brain mechanisms in the subject matter. This book, consisting of 11 chapters, starts with a basic description of thirst then to an analysis of basic physiological mechanisms that determine water intake. Another topic also discussed in this book is various experimental paradigms that resulted to the dual-depletion theory of thirst. The neuroanatomical, neuroendocrinologica... and neuropharmacological brain mechanisms are covered in three chapters of this book. These brain mechanisms respond to different peripheral signals that stimulate the thirst. The final chapters are dedicated to sodium appetite. Although it has lesser literature than thirst has, there have been significant developments in the understanding of the role of sodium appetite in extracellular thirst. The last chapter reviews the questions that has kept investigators at bay and recommends direction of where future research may go.

  • The Human Nervous System

    • 1 Edición
    • George Paxinos
    • Inglés
    The Human Nervous System is a definitive account of human neuroanatomy, with a comprehensive coverage of the brain, spinal cord, and peripheral nervous system. The cytoarchitecture, chemoarchitecture, connectivity, and major functions of neuronal structures are examined by acknowledged authorities in the field, such as: Alheid, Amaral, Armstrong, Beitz, Burke, de Olmos, Difiglia, Garey, Gerrits, Gibbins, Holstege, Kaas, Martin, McKinley, Norgren, Ohye, Paxinos, Pearson, Pioro, Price, Saper, Sasaki, Schoenen, Tadork, Voogd, Webster, Zilles, and their associates.

  • Principles of Neurobiological Signal Analysis

    • 1 Edición
    • Edmund Glaser
    • Inglés
    Principles of Neurobiological Signal Analysis deals with the principles of signal analysis as applied to the electrical activity of the nervous system. Topics covered include biological signals, the basics of signal processing, and power spectra and covariance functions. Evoked potentials, spontaneous and driven single unit activity, and multiunit activity are also considered, along with the relations between slow wave and unit activity. This book consists of eight chapters and begins by establishing the theoretical groundwork of signal analysis, with emphasis on the properties of signal and noise; sampling and conversion of biological signals into sequences of digital numbers readily digestible by a computer; and the concepts of power spectrum and covariance analysis. The following chapters explore techniques for extracting evoked responses from background noise; multivariate statistical procedures for treating evoked response waveshapes as variables dependent upon the experimental manipulations performed upon a subject; and spike (action potential) activity generated by neurons. The final chapter describes methods for studying how such spike activity may be related to the concurrently observed slow wave (EEG-like) activity of the nervous system. This monograph will be of interest to physiologists and neurobiologists.

  • Spinal Cord Injury

    • 1 Edición
    • Volumen 109
    • Joost Verhaagen + 1 más
    • Inglés
    Handbook of Clinical Neurology: Spinal Cord Injury summarizes advances in the clinical diagnosis, monitoring, prognostication, treatment, and management of spinal cord injuries. More specifically, it looks at new and important developments in areas such as high-resolution noninvasive neuroimaging, surgery, and electrical stimulation of motor, respiratory, bladder, bowel, and sexual functions. It also reviews the latest insights into spontaneous regeneration and recovery of function following rehabilitation, with emphasis on novel therapeutic strategies, such as gene therapy, transcranial stimulation, brain-machine interfaces, pharmacological approaches, molecular target discovery, and the use of olfactory ensheathing cells, stem cells, and precursor cells. Organized in five sections, the book begins with an overview of the development, maturation, biomechanics, and anatomy of the spinal cord before proceeding with a discussion of clinical diagnosis and prognosis as well as natural recovery, ambulation, and function following spinal cord injury. It then examines clinical neurophysiology in the prognosis and monitoring of traumatic spinal cord injury; medical, surgical and rehabilitative management of spinal cord trauma; and some new approaches for improving recovery in patients, including restoration of function by electrical stimulation, locomotor training, and the use of robotics. Other chapters cover cell transplantation, artificial scaffolds, experimental pharmacological interventions, and molecular and combinatorial strategies for repairing the injured spinal cord. This volume should be of interest to neuroscience and clinical neurology research specialists and practicing neurologists.

  • Fundamental Neuroscience

    • 4 Edición
    • Larry Squire + 5 más
    • Inglés
    The fourth edition of Fundamental Neuroscience reinvents itself as an engrossing and comprehensive presentation of the discipline of neuroscience, from molecules to cognition. Thorough but succinct, and lavishly illustrated, the book builds from an introductory section that includes fundamental neuroanatomy and goes on to cover cellular and molecular neuroscience, development, sensory systems, motor systems, regulatory systems, and behavioral and cognitive neuroscience. The book has been retooled to better serve its audience in the neuroscience and medical communities. The chapters include more than 100 boxes describing clinical conditions, techniques, and other special topics. Each chapter went through a thorough review process, giving the book an evenness of tone. The chapters are authored by outstanding working scientists who are experts on the topics they cover.

  • Sleep Disorders, An Issue of Neurologic Clinics

    • 1 Edición
    • Volumen 30-4
    • Bradley Vaughn
    • Inglés
    Sleep disorders are a widely recognized consequence of many neurological pathologies. This issue of Neurologic Clinics features the following articles: Sleep Physiology; Sleep Assessment Tools for the Neurologist; Fitting Sleep into Neurological Practice; Insomnia; Parasomnias and look-alikes; Sleep Apnea: Obstructive and central; Restless Legs syndrome; Circadian Rhythm; Pediatric Sleep Disorders; Dementia; Stroke; Epilepsy; CNS Immunological and Infectious; Movement Disorders; Neuromuscular ; Headache; Traumatic Brain Injury; and Psychiatry in Sleep.

  • The Neuroscience of Autism Spectrum Disorders

    • 1 Edición
    • Joseph D. Buxbaum + 1 más
    • Inglés
    Autism is no longer considered a rare disease, and the Center for Disease Control now estimates that upwards of 730,000 children in the US struggle with this isolating brain disorder. New research is leading to greater understanding of and ability to treat the disorder at an earlier age. It is hoped that further genetic and imaging studies will lead to biologically based diagnostic techniques that could help speed detection and allow early, more effective intervention. Edited by two leaders in the field, this volume offers a current survey and synthesis of the most important findings of the neuroscience behind autism of the past 20 years. With chapters authored by experts in each topic, the volume explores etiology, neuropathology, imaging, and pathways/models. Offering a broad background of ASDs with a unique focus on neurobiology, the volume offers more than the others on the market with a strictly clinical focus or a single authored perspective that fails to offer expert, comprehensive coverage. Researchers and graduate students alike with an interest in developmental disorders and autism will benefit, as will autism specialists across psychology and medicine looking to expand their expertise.

  • Rational Constructivism in Cognitive Development

    • 1 Edición
    • Volumen 43
    • Inglés
    Volume 43 of Advances in Child Development and Behavior includes chapters that highlight some of the most recent research in the area of Rational Constructivism. Each chapter provides in-depth discussions, and this volume serves as an invaluable resource for Developmental or educational psychology researchers, scholars, and students.

  • Epilepsy, Part I: Basic Principles and Diagnosis

    • 1 Edición
    • Volumen 107
    • Hermann Stefan + 1 más
    • Inglés
    Epilepsy, Part I, Basic Principles and Diagnosis, Volume 107, in the Handbook of Clinical Neurology series offers a comprehensive review of our knowledge of the field today, including epidemiology, basic mechanisms, animal models, and topics of increasing interest such as the role of inflammation in epilepsy. It provides a comprehensive approach to description of the clinical, electrographic and imaging aspects of the epilepsies, with a clear outline of contemporary classification and the role of modern diagnostic techniques, as well as neuropsychological and psychiatric aspects of epilepsy. Chapters are authored by internationally respected neurologists with varied perspectives insuring depth to the content. Epilepsy, Part II, Treatment, Volume 108, continues coverage of epilepsy with a focus on treatment. The volumes will be a very important resource for basic scientists, clinical investigators, and all health professionals treating patients with epilepsy.

  • Management of Pituitary Tumors, An Issue of Neurosurgery Clinics

    • 1 Edición
    • Volumen 23-4
    • Manish K. Aghi + 1 más
    • Inglés
    This issue of the Neurosurgery Clinics of North America, Guest Edited by Drs. Manish Aghi and Lewis Blevins, is devoted to Management of Pituitary Tumors. Experts in the field have assembled to provide articles on Imaging of the pituitary and parasellar region; Management of Incidentally Found Nonfunctional Pituitary Tumors; Endoscopic Surgery for Pituitary Tumors; Prolactinomas – Medical versus Surgical Management; Neurosurgery for Cushing’s Disease; Postoperative radiotherapy and stereotactic radiosurgery for pituitary tumors; Management options for persistent postoperative acromegaly; Medical management of persistent and recurrent Cushing’s disease; Management of Large Aggressive Nonfunctional Pituitary Tumors – Experimental Medical Options when Surgery and Radiation Fail; Pituitary Carcinoma; Visual Outcomes after Surgery For Nonfunctional Adenomas Causing Visual Compromise; and Hypopituitarism and Central Diabetes Insipidus: Peri-Operative Diagnosis and Management.

  • Epilepsy, Part II: Treatment

    • 1 Edición
    • Volumen 108
    • Hermann Stefan + 1 más
    • Inglés
    Epilepsy, Part II, Treatment, Volume 108, provides a full description of epilepsy pathology and etiology, antiepileptic drug treatment, the approach to surgical evaluation and alternative procedures to be considered, in both children and adults, as well as brain stimulation and diet treatment. Economic and psychosocial issues such as stigma are fully covered. The special problems of epilepsy treatment in the developing world are described. Chapters are authored by internationally respected neurologists with varied perspectives insuring depth to the content. Epilepsy, Part I, Basic Principles and Diagnosis, Volume 107, establishes the scientific and practical diagnosis of epilepsy. The volumes will be a very important resource for basic scientists, clinical investigators, and all health professionals treating patients with epilepsy.

  • Translational Neuroimaging

    Tools for CNS Drug Discovery, Development and Treatment
    • 1 Edición
    • Robert A. McArthur
    • Inglés
    Translational Neuroimaging: Tools for CNS Drug Discovery, Development and Treatment combines the experience of academic, clinical and industrial neuroimagers in a unique collaborative approach to provide an integrated perspective of the use of small animal and human brain imaging in developing and validating translational models and biomarkers for the study and treatment of neuropsychiatric disorders. Translational Neuroimaging: Tools for CNS Drug Discovery, Development and Treatment examines the translational role of neuroimaging in model development from preclinical animal models, to human experimental medicine, and finally to clinical studies. The focus of this book is to identify and provide common endpoints between species that can serve to inform both the clinic and the bench with the information needed to accelerate clinically-effective CNS drug discovery. This book covers methodical issues in human and animal neuroimaging translational research as well as detailed applied examples of the use of neuroimaging in neuropsychiatric disorders and the development of drugs for their treatment. Translational Neuroimaging: Tools for CNS Drug Discovery, Development and Treatment appeals to non-clinical and clinical neuroscientists working in and studying neuropsychiatric disorders and their treatment as well as providing the novice researcher or researcher outside of his/her expertise the opportunity to understand the background of translational research and the use of imaging in this field.

  • Neuropsychological Rehabilitation

    Principles and Applications
    • 1 Edición
    • Jamuna Rajeswaran
    • Inglés
    Traumatic Brain Injury (TBI) can occur through road traffic incidents, falls, or violence, and is therefore an extremely prevalent type of injury, constituting a significant burden on health care around the world. As more people are able to recover physically from TBI, it is important to consider how to help repair the cognitive functions of the brain. The cognitive functions could be greatly maximized by appropriate Neuropsychological rehabilitation, which occurs within months of the damage. This book discusses both the theoretical and practical applications of Neuropsychological rehabilitation techniques, offering a comprehensive overview of the process. Using several case studies from India, gained over years of clinical practice, research and academic teaching, this book offers an excellent guide to the procedures and tasks needed to respond effectively to patients with TBI. Although focused on the Indian context, this book will appeal to students and practitioners around the world as a useful resource on Neuropsychological rehabilitation techniques in India.

  • Gap Junctions in the Brain

    Physiological and Pathological Roles
    • 1 Edición
    • Ekrem Dere
    • Inglés
    Gap junctions between glial cells or neurons are ubiquitously expressed in the mammalian brain and play a role in brain development including cell differentiation, cell migration and survival, and tissue homeostasis, as well as in human diseases including hearing loss, neuropathies, epilepsy, brain trauma, and cardiovascular disease. This volume provides neuroscience researchers and students with a single source for information covering the physiological, behavioral and pathophysiological roles of gap junctions in the brain. In addition, the book also discusses human disease conditions associated with mutations in single gap junction connexion genes, making it applicable to clinicians doing translational research. Finally, it includes reviews of pharmacological studies with gap junction blockers and openers, summarizing information obtained from phenotyping gap junctions mouse mutants.

  • The Neurobiology of Circadian Timing

    • 1 Edición
    • Volumen 199
    • Inglés
    Approx.498 pages

  • Pregnancy and Neurologic Illness, An Issue of Neurologic Clinics

    • 1 Edición
    • Volumen 30-3
    • Autumn Klein
    • Inglés
    Neurologic illness in pregnant women requires special consideration on the part of the neurologist. These disorders can impact pregnancy in distinct ways, and their therapies must often be modified to protect the health of the mother and fetus. This issue of Neurologic Clinics features 11 articles on the interaction of the main neurologic disorders and pregnancy.

  • Cellular Imaging Techniques for Neuroscience and Beyond

    • 1 Edición
    • Floris G. Wouterlood
    • Inglés
    The imaging of small cellular components requires powerful instruments, and an entire family of equipment and techniques based on the confocal principle has been developed over the past 30 years. Such methods are commonly used by neuroscience researchers, but the majority of these users do not have a microscopy or a cell biology backgrounds and do can encounter difficulties in obtaining and interpreting results. This volume brings experts in high-resolution optical microscopy applications in neuroscience and cell biology together to document the state of the art. Outlining what is currently possible, the volume also discusses promising developments for the future and aids readers in selecting the most scientifically meaningful approach to solve their questions. Each chapter discusses instrumentation and technology in relationship to application in research. All of the common and cutting edge trends are covered - fluorescence / laser electron / nonlinear microscopy, infrared fluorescence, multiphoton imaging, tomography, FRAP, live imaging, STED, PALM/STORM, etc.

  • Inflammation in Neuropsychiatric Disorders

    • 1 Edición
    • Volumen 88
    • Inglés
    Published continuously since 1944, the Advances in Protein Chemistry and Structural Biology serial has been a continuous, essential resource for protein chemists. Covering reviews of methodology and research in all aspects of protein chemistry, including purification/express... proteomics, modeling and structural determination and design, each volume brings forth new information about protocols and analysis of proteins while presenting the most recent findings from leading experts in a broad range of protein-related topics.

  • Orexin/Hypocretin System

    • 1 Edición
    • Volumen 198
    • Inglés
    Leading authors review the state-of-the-art in their field of investigation, and provide their views and perspectives for future research. Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered. All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist.

  • Sleep and Brain Activity

    • 1 Edición
    • Marcos G. Frank
    • Inglés
    In the last few decades, scientists have discovered that far from being a time of neural silence, sleep is characterized by complex patterns of electrical, neurochemical, and metabolic activity in the brain. Sleep and the Brain presents some of the more dramatic developments in our understanding of brain activity in sleep. The book discusses what parts of the brain are active in sleep and how, and presents research on the function of sleep in memory, learning, and further brain development. Coverage encompasses the network and membrane mechanisms responsible for waking and sleeping brain activity, the roles of glial cells in the sleeping brain, the molecular basis of sleep EEG rhythms, and research on songbirds, rodents, and humans indicating the function of sleep.

  • New Perspectives of Central Nervous System Injury and Neuroprotection

    • 1 Edición
    • Volumen 102
    • Inglés
    Central nervous system (CNS) diseases such as Alzheimer’s disease, Parkinson’s disease, and amyotrophic lateral sclerosis affect a large number of populations worldwide for which no suitable cure is currently available. In addition, stroke, nanoparticle intoxication, diabetes, hypertension, and psychostimulant abuse either alone or in combination are capable of inducing potential brain damage. Thus, there is an urgent need to expand our knowledge to find suitable therapeutic strategies to enhance neurorepair processes in such diseases.This volume presents neuroprotection and novel therapeutic strategies developed in the last 5 years by 12 world leaders in the field. The term neuroprotection means rescuing neuronal and non-neuronal cells together. The cerebral endothelium that constitutes the anatomical and physiological site of the blood-brain barrier (BBB) is one of the most important non-neural cells in the CNS. Any distortion of the BBB leads to brain diseases and restoration of the barrier results in neuroprotection. Thus, the BBB appears to be the "gateway" for neurological diseases and neurorepair. However, to treat brain tumors or infarcts, new therapeutic strategies are needed to enhance brain drug delivery using nanotechnology. In addition, apart from conventional drugs, restoration of BBB function could also be achieved by means of antibodies directed against specific proteins, neurotransmitters or exogenous supplement of neurotrophic factors. Since co-morbidity factors e.g., hypertension, diabetes, and exposure of nanoparticles could complicate the pathogenesis of neurological disorders either an enhanced dose of the drug or nanodelivery of a combination of several drugs is needed to achieve neuroprotection.This volume of International Review of Neurobiology is the first to discuss novel therapeutic strategies in situations of neurological disorders in combination with different co-morbidity factors.

  • Modern Management of High Grade Glioma, Part II, An Issue of Neurosurgery Clinics

    • 1 Edición
    • Volumen 23-3
    • Isaac Yang + 1 más
    • Inglés
    Standard therapy for high grade glioma is a topic that is evolving, timely, and relevant. Guest Editors Isaac Yang, MD and Seunggu Han, MD have assembled a group of experts on management of high grade glioma. Some of the articles in this issue include: Use of language mapping to aid resection of eloquent gliomas; Clinical trials with immunotherapy; Clinical trials for small molecule inhibitors; Nanotechnology potential applications for GBM therapy; High Grade Gliomas in children; Modern Advances in Brain Tumor Treatments; Molecular pathways of Avastin interactions for the treatment of glioblastoma; and Quality of Life and Outcomes in Glioblastoma management.

  • Fundamentals of Motor Control

    • 1 Edición
    • Mark L. Latash
    • Inglés
    Motor control is a relatively young field of research exploring how the nervous system produces purposeful, coordinated movements in its interaction with the body and the environment through conscious and unsconscious thought. Many books purporting to cover motor control have veered off course to examine biomechanics and physiology rather than actual control, leaving a gap in the literature. This book covers all the major perspectives in motor control, with a balanced approach. There are chapters explicitly dedicated to control theory, to dynamical systems, to biomechanics, to different behaviors, and to motor learning, including case studies.

  • Neurobiology of Psychiatric Disorders

    • 1 Edición
    • Volumen 106
    • Thomas E Schlaepfer + 1 más
    • Inglés
    This new volume in the Handbook of Clinical Neurology presents a comprehensive review of the fundamental science and clinical treatment of psychiatric disorders. Advances in neuroscience have allowed for dramatic advances in the understanding of psychiatric disorders and treatment. Brain disorders, such as depression and schizophrenia, are the leading cause of disability worldwide. It is estimated that over 25% of the adult population in North America are diagnosed yearly with at least one mental disorder and similar results hold for Europe. Now that neurology and psychiatry agree that all mental disorders are in fact, "brain diseases," this volume provides a foundational introduction to the science defining these disorders and details best practices for psychiatric treatment.

  • Down Syndrome: From Understanding the Neurobiology to Therapy

    • 1 Edición
    • Volumen 197
    • Inglés
    Down syndrome (DS) is the most common example of neurogenetic aneuploid disorder leading to mental retardation. In most cases, DS results from an extra copy of chromosome 21 (HSA21) producing deregulated gene expression in brain that gives raise to subnormal intellectual functioning. The topic of this volume is of broad interest for the neuroscience community, because it tackles the concept of neurogenomics, that is, how the genome as a whole contributes to a neurodevelopmental cognitive disorders, such as DS, and thus to the development, structure and function of the nervous system. This volume of Progress in Brain Research discusses comparative genomics, gene expression atlases of the brain, network genetics, engineered mouse models and applications to human and mouse behavioral and cognitive phenotypes. It brings together scientists of diverse backgrounds, by facilitating the integration of research directed at different levels of biological organization, and by highlighting translational research and the application of the existing scientific knowledge to develop improved DS treatments and cures.

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